uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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|---|---|---|---|---|---|---|---|---|
Q67.506 | Q67 | What is the top-associated SNP of the gene NFYA in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for NFYA in Whole Blood eQTL eQTLgen omic data for AD is rs11964892, which has a multi-SNP SMR p-value of 4.00e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NFYA" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1494866', 'topRSID': 'rs11964892', 'Disease': 'AD', 'Gene': 'NFYA', 'p_SMR_multi': 4.000049e-09, 'p_HEIDI': 5.671352e-10, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1670 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for PSP is rs8070723, which has a multi-SNP SMR p-value of 7.66e-18 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560864', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'MAPT', 'p_SMR_multi': 2.100115e-44, 'p_HEIDI': 0.01425494, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_56... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.182 | Q67 | What is the top-associated SNP of the gene APOC2 in Prefrontal Cortex eQTL omic data for AD and is it functionally significant? | The top-associated SNP for APOC2 in Prefrontal Cortex eQTL omic data for AD is rs9304644, which has a multi-SNP SMR p-value of 2.58e-08 and a HEIDI of 0.13, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APOC2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1203800', 'topRSID': 'rs9304644', 'Disease': 'AD', 'Gene': 'APOC2', 'p_SMR_multi': 2.581525e-08, 'p_HEIDI': 0.1269466, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1419 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Cortex eQTL metaBrain omic data for AD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Cortex eQTL metaBrain omic data for AD is rs2696466, which has a multi-SNP SMR p-value of 3.80e-08 and a HEIDI of 0.9, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1106833', 'topRSID': 'rs2696466', 'Disease': 'AD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 3.800326e-08, 'p_HEIDI': 0.8992636, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1014 | Q67 | What is the top-associated SNP of the gene MSI2 in Whole Blood mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene MSI2 in Whole Blood mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MSI2" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_833820', 'topRSID': 'rs72833094', 'Disease': 'FTD', 'Gene': 'MSI2', 'p_SMR_multi': 0.1134534, 'p_HEIDI': 0.9586158, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_833817', 'topRS... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1978 | Q67 | What is the top-associated SNP of the gene NDUFAF6 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for NDUFAF6 in Whole Brain meta-analysis mQTL omic data for AD is rs10097617, which has a multi-SNP SMR p-value of 2.46e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NDUFAF6" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_79381', 'topRSID': 'rs10097617', 'Disease': 'AD', 'Gene': 'NDUFAF6', 'p_SMR_multi': 2.455946e-08, 'p_HEIDI': 0.001210675, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.864 | Q67 | What is the top-associated SNP of the gene GLTSCR2 in Prefrontal Cortex eQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene GLTSCR2 in Prefrontal Cortex eQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GLTSCR2" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1213817', 'topRSID': 'rs3181870', 'Disease': 'ALS', 'Gene': 'GLTSCR2', 'p_SMR_multi': 0.5623373, 'p_HEIDI': 0.07453255, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1620 | Q67 | What is the top-associated SNP of the gene POLR2E in Whole Brain eQTL omic data for AD and is it functionally significant? | The top-associated SNP for POLR2E in Whole Brain eQTL omic data for AD is rs3787016, which has a multi-SNP SMR p-value of 1.23e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "POLR2E" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1611203', 'topRSID': 'rs3787016', 'Disease': 'AD', 'Gene': 'POLR2E', 'p_SMR_multi': 1.227713e-07, 'p_HEIDI': 0.004171978, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.534 | Q67 | What is the top-associated SNP of the gene NDUFAF6 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for NDUFAF6 in Whole Brain meta-analysis mQTL omic data for AD is rs896853, which has a multi-SNP SMR p-value of 3.41e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NDUFAF6" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_79381', 'topRSID': 'rs10097617', 'Disease': 'AD', 'Gene': 'NDUFAF6', 'p_SMR_multi': 2.455946e-08, 'p_HEIDI': 0.001210675, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.350 | Q67 | What is the top-associated SNP of the gene ACSS2 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene ACSS2 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ACSS2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1398020', 'topRSID': 'rs6087646', 'Disease': 'AD', 'Gene': 'ACSS2', 'p_SMR_multi': 0.002095111, 'p_HEIDI': 0.001714403, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1389 | Q67 | What is the top-associated SNP of the gene SFTA2 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for SFTA2 in Whole Blood mQTL omic data for AD is rs3132556, which has a multi-SNP SMR p-value of 1.03e-07 and a HEIDI of 0.13, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SFTA2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_620616', 'topRSID': 'rs2233980', 'Disease': 'AD', 'Gene': 'SFTA2', 'p_SMR_multi': 4.13716e-08, 'p_HEIDI': 0.02253225, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_620617', 'topRSID... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1961 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for PSP is rs6503455, which has a multi-SNP SMR p-value of 9.94e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560864', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'MAPT', 'p_SMR_multi': 2.100115e-44, 'p_HEIDI': 0.01425494, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_56... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1301 | Q67 | What is the top-associated SNP of the gene TMEM175 in Cerebellum eQTL omic data for PD and is it functionally significant? | The top-associated SNP for TMEM175 in Cerebellum eQTL omic data for PD is rs73211813, which has a multi-SNP SMR p-value of 7.71e-07 and a HEIDI of 0.33, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TMEM175" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1707342', 'topRSID': 'rs73211813', 'Disease': 'PD', 'Gene': 'TMEM175', 'p_SMR_multi': 7.710669e-07, 'p_HEIDI': 0.3303648, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_19049', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1973 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 1.21e-31 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041740', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'MAPT', 'p_SMR_multi': 3.1929999999999995e-44, 'p_HEIDI': 3.11336e-12, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1980 | Q67 | What is the top-associated SNP of the gene PILRB in Prefrontal Cortex eQTL omic data for AD and is it functionally significant? | The top-associated SNP for PILRB in Prefrontal Cortex eQTL omic data for AD is rs6975660, which has a multi-SNP SMR p-value of 1.82e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PILRB" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1198853', 'topRSID': 'rs6975660', 'Disease': 'AD', 'Gene': 'PILRB', 'p_SMR_multi': 1.815993e-07, 'p_HEIDI': 9.662354e-05, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.608 | Q67 | What is the top-associated SNP of the gene HSD3B7 in Skeletal Muscle eQTL omic data for AD and is it functionally significant? | The top-associated SNP for HSD3B7 in Skeletal Muscle eQTL omic data for AD is rs13708, which has a multi-SNP SMR p-value of 2.87e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "HSD3B7" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1342788', 'topRSID': 'rs13708', 'Disease': 'AD', 'Gene': 'HSD3B7', 'p_SMR_multi': 2.873879e-06, 'p_HEIDI': 0.001643226, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1050 | Q67 | What is the top-associated SNP of the gene LRRC37A4P in Skeletal Muscle eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A4P in Skeletal Muscle eQTL omic data for PD is rs757055, which has a multi-SNP SMR p-value of 1.18e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A4P" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1370537', 'topRSID': 'rs757055', 'Disease': 'PD', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 1.183314e-13, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.246 | Q67 | What is the top-associated SNP of the gene LRRC37A in Prefrontal Cortex eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A in Prefrontal Cortex eQTL omic data for PD is rs566238830, which has a multi-SNP SMR p-value of 1.88e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1242281', 'topRSID': 'rs566238830', 'Disease': 'PD', 'Gene': 'LRRC37A', 'p_SMR_multi': 1.879442e-15, 'p_HEIDI': 0.005536709, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1681 | Q67 | What is the top-associated SNP of the gene LARS2 in Frontal Cortex BA9 eQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene LARS2 in Frontal Cortex BA9 eQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LARS2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%frontal cortex ba9 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1155321', 'topRSID': 'rs3821895', 'Disease': 'AD', 'Gene': 'LARS2', 'p_SMR_multi': 0.04695836, 'p_HEIDI': 0.3003719, 'Omic_tissue': 'Frontal Cortex', 'Omic_type': 'Frontal Cortex BA9 eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1799 | Q67 | What is the top-associated SNP of the gene C1orf21 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene C1orf21 in Whole Brain meta-analysis mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C1orf21" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_40628', 'topRSID': 'rs61502552', 'Disease': 'AD', 'Gene': 'C1orf21', 'p_SMR_multi': 0.1908536, 'p_HEIDI': 0.6101899, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1717 | Q67 | What is the top-associated SNP of the gene LRRC37A4P in Hypothalamus eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A4P in Hypothalamus eQTL omic data for PD is rs112155389, which has a multi-SNP SMR p-value of 5.02e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A4P" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%hypothalamus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1462889', 'topRSID': 'rs112155389', 'Disease': 'PD', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 5.015928e-12, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Hypothalamus', 'Omic_type': 'Hypothalamus eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage D... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.316 | Q67 | What is the top-associated SNP of the gene RP11-259G18.3 in Tibial Nerve eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.3 in Tibial Nerve eQTL omic data for PD is rs199456, which has a multi-SNP SMR p-value of 4.23e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.3" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1328936', 'topRSID': 'rs199456', 'Disease': 'PD', 'Gene': 'RP11-259G18.3', 'p_SMR_multi': 4.22626e-14, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage D... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.441 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Skeletal Muscle eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A2 in Skeletal Muscle eQTL omic data for PSP is rs7225002, which has a multi-SNP SMR p-value of 3.00e-25 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1375936', 'topRSID': 'rs7225002', 'Disease': 'PSP', 'Gene': 'LRRC37A2', 'p_SMR_multi': 2.998771e-25, 'p_HEIDI': 3.760397e-19, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1899 | Q67 | What is the top-associated SNP of the gene GAK in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for GAK in Whole Blood mQTL omic data for PD is rs10029038, which has a multi-SNP SMR p-value of 1.06e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GAK" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996273', 'topRSID': 'rs12651271', 'Disease': 'PD', 'Gene': 'GAK', 'p_SMR_multi': 6.180527e-09, 'p_HEIDI': 3.619298e-07, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1637 | Q67 | What is the top-associated SNP of the gene PRR14 in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for PRR14 in Whole Blood eQTL eQTLgen omic data for PD is rs4616297, which has a multi-SNP SMR p-value of 1.76e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PRR14" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1563800', 'topRSID': 'rs4616297', 'Disease': 'PD', 'Gene': 'PRR14', 'p_SMR_multi': 1.759651e-07, 'p_HEIDI': 0.002092658, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.312 | Q67 | What is the top-associated SNP of the gene RP11-259G18.1 in Cerebellum eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.1 in Cerebellum eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 6.40e-23 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1714159', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'RP11-259G18.1', 'p_SMR_multi': 6.403575000000001e-23, 'p_HEIDI': 3.5744260000000003e-25, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows sign... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.436 | Q67 | What is the top-associated SNP of the gene RBFOX3 in Whole Blood mQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene RBFOX3 in Whole Blood mQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RBFOX3" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1043153', 'topRSID': 'rs6501286', 'Disease': 'PSP', 'Gene': 'RBFOX3', 'p_SMR_multi': 0.0968993, 'p_HEIDI': 0.124753, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1043144', 'top... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.667 | Q67 | What is the top-associated SNP of the gene ARL17A in Tibial Nerve eQTL omic data for AD and is it functionally significant? | The top-associated SNP for ARL17A in Tibial Nerve eQTL omic data for AD is rs62074125, which has a multi-SNP SMR p-value of 2.55e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1291769', 'topRSID': 'rs62074125', 'Disease': 'AD', 'Gene': 'ARL17A', 'p_SMR_multi': 2.553728e-06, 'p_HEIDI': 3.862198e-07, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.376 | Q67 | What is the top-associated SNP of the gene PLEKHM1 in Nucleus Accumbens Basal Ganglia omic data for PSP and is it functionally significant? | The top-associated SNP for PLEKHM1 in Nucleus Accumbens Basal Ganglia omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 8.48e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PLEKHM1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1732389', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'PLEKHM1', 'p_SMR_multi': 8.479211e-12, 'p_HEIDI': 1.057079e-05, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'association meets significance threshold but shows si... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.572 | Q67 | What is the top-associated SNP of the gene PERP in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | There are no SNPs within the gene PERP in Whole Blood eQTL eQTLgen omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PERP" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1557514', 'topRSID': 'rs75604586', 'Disease': 'PD', 'Gene': 'PERP', 'p_SMR_multi': 0.1261666, 'p_HEIDI': 0.1537251, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1226 | Q67 | What is the top-associated SNP of the gene MAPT-AS1 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT-AS1 in Whole Brain meta-analysis mQTL omic data for PD is rs56280951, which has a multi-SNP SMR p-value of 3.97e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491096', 'topRSID': 'rs56280951', 'Disease': 'PD', 'Gene': 'MAPT-AS1', 'p_SMR_multi': 3.97087e-15, 'p_HEIDI': 0.001150121, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.184 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain eQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain eQTL omic data for PD is rs62641967, which has a multi-SNP SMR p-value of 6.98e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1640220', 'topRSID': 'rs62641967', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 6.975485e-12, 'p_HEIDI': 0.000110669, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1115 | Q67 | What is the top-associated SNP of the gene DND1P1 in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for DND1P1 in Whole Blood mQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 9.42e-44 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DND1P1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041717', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'DND1P1', 'p_SMR_multi': 9.423973e-44, 'p_HEIDI': 8.563959e-12, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.628 | Q67 | What is the top-associated SNP of the gene RP11-707O23.5 in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for RP11-707O23.5 in Whole Blood eQTL eQTLgen omic data for PD is rs2532233, which has a multi-SNP SMR p-value of 3.99e-09 and a HEIDI of 0.03, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-707O23.5" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1564781', 'topRSID': 'rs2532233', 'Disease': 'PD', 'Gene': 'RP11-707O23.5', 'p_SMR_multi': 3.988953e-09, 'p_HEIDI': 0.02790569, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1910 | Q67 | What is the top-associated SNP of the gene RIMBP2 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene RIMBP2 in Whole Brain meta-analysis mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RIMBP2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_98291', 'topRSID': 'rs61935898', 'Disease': 'AD', 'Gene': 'RIMBP2', 'p_SMR_multi': 0.07337848, 'p_HEIDI': 0.6847391, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1192 | Q67 | What is the top-associated SNP of the gene ABCA7 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for ABCA7 in Whole Blood mQTL omic data for AD is rs4147922, which has a multi-SNP SMR p-value of 5.90e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ABCA7" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_634279', 'topRSID': 'rs3764642', 'Disease': 'AD', 'Gene': 'ABCA7', 'p_SMR_multi': 2.490416e-10, 'p_HEIDI': 0.0002263415, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.940 | Q67 | What is the top-associated SNP of the gene RMI2 in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene RMI2 in Whole Brain meta-analysis mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RMI2" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_389735', 'topRSID': 'rs6498179', 'Disease': 'LBD', 'Gene': 'RMI2', 'p_SMR_multi': 0.2551737, 'p_HEIDI': 0.6404786, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_38... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1774 | Q67 | What is the top-associated SNP of the gene HCG17 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for HCG17 in Whole Blood mQTL omic data for AD is rs139747027, which has a multi-SNP SMR p-value of 2.55e-06 and a HEIDI of 0.26, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "HCG17" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_620392', 'topRSID': 'rs139747027', 'Disease': 'AD', 'Gene': 'HCG17', 'p_SMR_multi': 2.546484e-06, 'p_HEIDI': 0.2610588, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_620391', 'topRS... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1842 | Q67 | What is the top-associated SNP of the gene EPHA1 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for EPHA1 in Whole Blood eQTL eQTLgen omic data for AD is rs7794735, which has a multi-SNP SMR p-value of 4.98e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "EPHA1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1496071', 'topRSID': 'rs7794735', 'Disease': 'AD', 'Gene': 'EPHA1', 'p_SMR_multi': 4.978741e-12, 'p_HEIDI': 8.813917e-10, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1331 | Q67 | What is the top-associated SNP of the gene NDUFAF6 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for NDUFAF6 in Whole Blood mQTL omic data for AD is rs6987752, which has a multi-SNP SMR p-value of 2.36e-06 and a HEIDI of 0.23, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NDUFAF6" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_616798', 'topRSID': 'rs1320164', 'Disease': 'AD', 'Gene': 'NDUFAF6', 'p_SMR_multi': 1.716817e-06, 'p_HEIDI': 0.2600196, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_616796', 'topRS... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.300 | Q67 | What is the top-associated SNP of the gene ANKRD11 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene ANKRD11 in Whole Brain meta-analysis mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ANKRD11" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_112005', 'topRSID': 'rs3102357', 'Disease': 'AD', 'Gene': 'ANKRD11', 'p_SMR_multi': 0.1148581, 'p_HEIDI': 0.2007293, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1619 | Q67 | What is the top-associated SNP of the gene TSPAN14 in Prefrontal Cortex eQTL omic data for AD and is it functionally significant? | The top-associated SNP for TSPAN14 in Prefrontal Cortex eQTL omic data for AD is rs10749609, which has a multi-SNP SMR p-value of 2.37e-07 and a HEIDI of 0.15, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TSPAN14" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1200108', 'topRSID': 'rs10749609', 'Disease': 'AD', 'Gene': 'TSPAN14', 'p_SMR_multi': 2.370245e-07, 'p_HEIDI': 0.1507844, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.467 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for PD is rs2435204, which has a multi-SNP SMR p-value of 3.40e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491114', 'topRSID': 'rs17652121', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 4.729064e-14, 'p_HEIDI': 0.04416005, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_49... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1302 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for PD is rs62063859, which has a multi-SNP SMR p-value of 1.72e-09 and a HEIDI of 0.16, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491114', 'topRSID': 'rs17652121', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 4.729064e-14, 'p_HEIDI': 0.04416005, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_49... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1250 | Q67 | What is the top-associated SNP of the gene AC006033.22 in Whole Blood mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene AC006033.22 in Whole Blood mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AC006033.22" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_808180', 'topRSID': 'rs2286693', 'Disease': 'FTD', 'Gene': 'AC006033.22', 'p_SMR_multi': 0.3620872, 'p_HEIDI': 0.3139577, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_808181', ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.383 | Q67 | What is the top-associated SNP of the gene PLEKHM1 in Cerebellum eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for PLEKHM1 in Cerebellum eQTL omic data for PSP is rs393152, which has a multi-SNP SMR p-value of 8.31e-25 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PLEKHM1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_22215', 'topRSID': 'rs393152', 'Disease': 'PSP', 'Gene': 'PLEKHM1', 'p_SMR_multi': 8.306359e-25, 'p_HEIDI': 1.696664e-21, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1768 | Q67 | What is the top-associated SNP of the gene SLX1B in Cortex eQTL metaBrain omic data for AD and is it functionally significant? | The top-associated SNP for SLX1B in Cortex eQTL metaBrain omic data for AD is rs2083237, which has a multi-SNP SMR p-value of 1.92e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SLX1B" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1111642', 'topRSID': 'rs2083237', 'Disease': 'AD', 'Gene': 'SLX1B', 'p_SMR_multi': 1.921527e-08, 'p_HEIDI': 4.376231e-05, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.108 | Q67 | What is the top-associated SNP of the gene CNN2 in Cortex eQTL metaBrain omic data for AD and is it functionally significant? | The top-associated SNP for CNN2 in Cortex eQTL metaBrain omic data for AD is rs4807440, which has a multi-SNP SMR p-value of 4.32e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CNN2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1107631', 'topRSID': 'rs4807440', 'Disease': 'AD', 'Gene': 'CNN2', 'p_SMR_multi': 4.321563e-07, 'p_HEIDI': 3.694892e-08, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.129 | Q67 | What is the top-associated SNP of the gene GAK in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for GAK in Whole Brain meta-analysis mQTL omic data for PD is rs11248057, which has a multi-SNP SMR p-value of 1.49e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GAK" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_429832', 'topRSID': 'rs11248057', 'Disease': 'PD', 'Gene': 'GAK', 'p_SMR_multi': 1.488653e-10, 'p_HEIDI': 1.165356e-06, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1131 | Q67 | What is the top-associated SNP of the gene KAT8 in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for KAT8 in Whole Blood eQTL eQTLgen omic data for PD is rs1060506, which has a multi-SNP SMR p-value of 2.91e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KAT8" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1563818', 'topRSID': 'rs1060506', 'Disease': 'PD', 'Gene': 'KAT8', 'p_SMR_multi': 2.914295e-09, 'p_HEIDI': 9.02986e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.872 | Q67 | What is the top-associated SNP of the gene C3orf62 in Whole Blood mQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene C3orf62 in Whole Blood mQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C3orf62" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1033180', 'topRSID': 'rs11715581', 'Disease': 'PSP', 'Gene': 'C3orf62', 'p_SMR_multi': 0.165836, 'p_HEIDI': 0.6452529, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1033181', 't... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.360 | Q67 | What is the top-associated SNP of the gene RP11-259G18.3 in Hypothalamus eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.3 in Hypothalamus eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 5.77e-17 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.3" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%hypothalamus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1464420', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'RP11-259G18.3', 'p_SMR_multi': 5.766183e-17, 'p_HEIDI': 2.799671e-13, 'Omic_tissue': 'Hypothalamus', 'Omic_type': 'Hypothalamus eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1617 | Q67 | What is the top-associated SNP of the gene RP11-834C11.3 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene RP11-834C11.3 in Whole Brain meta-analysis mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-834C11.3" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_472081', 'topRSID': 'rs11612490', 'Disease': 'PD', 'Gene': 'RP11-834C11.3', 'p_SMR_multi': 0.1162996, 'p_HEIDI': 0.3321315, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_updat... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.689 | Q67 | What is the top-associated SNP of the gene ATF6B in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for ATF6B in Whole Blood mQTL omic data for AD is rs41316748, which has a multi-SNP SMR p-value of 1.18e-07 and a HEIDI of 0.15, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ATF6B" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_621490', 'topRSID': 'rs41316748', 'Disease': 'AD', 'Gene': 'ATF6B', 'p_SMR_multi': 1.175583e-07, 'p_HEIDI': 0.1501221, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_621492', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1787 | Q67 | What is the top-associated SNP of the gene CASS4 in Whole Blood eQTL GTEx omic data for AD and is it functionally significant? | The top-associated SNP for CASS4 in Whole Blood eQTL GTEx omic data for AD is rs6014722, which has a multi-SNP SMR p-value of 2.49e-07 and a HEIDI of 0.2, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CASS4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1653496', 'topRSID': 'rs6014722', 'Disease': 'AD', 'Gene': 'CASS4', 'p_SMR_multi': 2.493025e-07, 'p_HEIDI': 0.2014311, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1467 | Q67 | What is the top-associated SNP of the gene TCN1 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for TCN1 in Whole Blood eQTL eQTLgen omic data for AD is rs12419784, which has a multi-SNP SMR p-value of 6.99e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TCN1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1498258', 'topRSID': 'rs12419784', 'Disease': 'AD', 'Gene': 'TCN1', 'p_SMR_multi': 6.992786e-13, 'p_HEIDI': 4.993905e-07, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.212 | Q67 | What is the top-associated SNP of the gene TMA7 in Frontal Cortex BA9 eQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene TMA7 in Frontal Cortex BA9 eQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TMA7" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%frontal cortex ba9 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1166962', 'topRSID': 'rs9826247', 'Disease': 'PD', 'Gene': 'TMA7', 'p_SMR_multi': 0.06712888, 'p_HEIDI': 0.5053571, 'Omic_tissue': 'Frontal Cortex', 'Omic_type': 'Frontal Cortex BA9 eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.880 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PD is rs56212100, which has a multi-SNP SMR p-value of 2.23e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491057', 'topRSID': 'rs62065376', 'Disease': 'PD', 'Gene': 'ARHGAP27', 'p_SMR_multi': 1.134698e-11, 'p_HEIDI': 0.3072466, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.143 | Q67 | What is the top-associated SNP of the gene STAG3 in Tibial Nerve eQTL omic data for AD and is it functionally significant? | The top-associated SNP for STAG3 in Tibial Nerve eQTL omic data for AD is rs13230744, which has a multi-SNP SMR p-value of 2.22e-06 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "STAG3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1287871', 'topRSID': 'rs13230744', 'Disease': 'AD', 'Gene': 'STAG3', 'p_SMR_multi': 2.223335e-06, 'p_HEIDI': 0.01948462, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1439 | Q67 | What is the top-associated SNP of the gene NR5A2 in Cortex eQTL metaBrain omic data for FTD and is it functionally significant? | There are no SNPs within the gene NR5A2 in Cortex eQTL metaBrain omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NR5A2" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1123588', 'topRSID': 'rs2737655', 'Disease': 'FTD', 'Gene': 'NR5A2', 'p_SMR_multi': 0.7310794, 'p_HEIDI': 0.6018039, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1341 | Q67 | What is the top-associated SNP of the gene DOC2A in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for DOC2A in Whole Brain meta-analysis mQTL omic data for AD is rs10871451, which has a multi-SNP SMR p-value of 7.53e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DOC2A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_109454', 'topRSID': 'rs10871451', 'Disease': 'AD', 'Gene': 'DOC2A', 'p_SMR_multi': 7.531563e-08, 'p_HEIDI': 0.000390338, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1786 | Q67 | What is the top-associated SNP of the gene KAT8 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for KAT8 in Whole Blood mQTL omic data for AD is rs1978485, which has a multi-SNP SMR p-value of 6.79e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KAT8" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_577507', 'topRSID': 'rs1978487', 'Disease': 'AD', 'Gene': 'KAT8', 'p_SMR_multi': 2.552341e-07, 'p_HEIDI': 0.06856892, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_577509', 'topRSID... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1575 | Q67 | What is the top-associated SNP of the gene VAV2 in Whole Brain meta-analysis mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene VAV2 in Whole Brain meta-analysis mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "VAV2" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_271783', 'topRSID': 'rs654182', 'Disease': 'FTD', 'Gene': 'VAV2', 'p_SMR_multi': 0.07519397, 'p_HEIDI': 0.8319776, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_27... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1865 | Q67 | What is the top-associated SNP of the gene TRIM40 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for TRIM40 in Whole Blood mQTL omic data for AD is rs114882073, which has a multi-SNP SMR p-value of 1.52e-06 and a HEIDI of 0.73, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TRIM40" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_620281', 'topRSID': 'rs115938232', 'Disease': 'AD', 'Gene': 'TRIM40', 'p_SMR_multi': 3.571278e-07, 'p_HEIDI': 0.7820669, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_620283', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1749 | Q67 | What is the top-associated SNP of the gene RP11-259G18.2 in Caudate Basal Ganglia eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.2 in Caudate Basal Ganglia eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 4.03e-18 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1283704', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'RP11-259G18.2', 'p_SMR_multi': 4.029124e-18, 'p_HEIDI': 1.80629e-11, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows sig... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.718 | Q67 | What is the top-associated SNP of the gene RP11-430C7.4 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | There are no SNPs within the gene RP11-430C7.4 in Whole Blood eQTL eQTLgen omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-430C7.4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1491118', 'topRSID': 'rs12027855', 'Disease': 'AD', 'Gene': 'RP11-430C7.4', 'p_SMR_multi': 0.7956367, 'p_HEIDI': 0.9812983, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1936 | Q67 | What is the top-associated SNP of the gene CELF1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CELF1 in Whole Blood mQTL omic data for AD is rs7124681, which has a multi-SNP SMR p-value of 1.97e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CELF1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_608497', 'topRSID': 'rs11039409', 'Disease': 'AD', 'Gene': 'CELF1', 'p_SMR_multi': 1.22676e-06, 'p_HEIDI': 0.3753996, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_608498', 'topRSID... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.852 | Q67 | What is the top-associated SNP of the gene MMRN1 in Tibial Nerve eQTL omic data for PD and is it functionally significant? | The top-associated SNP for MMRN1 in Tibial Nerve eQTL omic data for PD is rs76644078, which has a multi-SNP SMR p-value of 9.67e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MMRN1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1323565', 'topRSID': 'rs76644078', 'Disease': 'PD', 'Gene': 'MMRN1', 'p_SMR_multi': 9.670789e-11, 'p_HEIDI': 0.0001763519, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage D... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1938 | Q67 | What is the top-associated SNP of the gene PLEKHM1 in Cerebellum eQTL omic data for PD and is it functionally significant? | The top-associated SNP for PLEKHM1 in Cerebellum eQTL omic data for PD is rs1991556, which has a multi-SNP SMR p-value of 3.70e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PLEKHM1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_19645', 'topRSID': 'rs62065453', 'Disease': 'PD', 'Gene': 'PLEKHM1', 'p_SMR_multi': 8.047881e-13, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequilib... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.11 | Q67 | What is the top-associated SNP of the gene SNCA in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for SNCA in Whole Brain meta-analysis mQTL omic data for PD is rs1372518, which has a multi-SNP SMR p-value of 1.42e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SNCA" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_432414', 'topRSID': 'rs3756059', 'Disease': 'PD', 'Gene': 'SNCA', 'p_SMR_multi': 2.653319e-12, 'p_HEIDI': 9.429443e-19, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1695 | Q67 | What is the top-associated SNP of the gene DYDC2 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for DYDC2 in Whole Blood mQTL omic data for AD is rs2185425, which has a multi-SNP SMR p-value of 2.18e-07 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DYDC2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_572628', 'topRSID': 'rs2185425', 'Disease': 'AD', 'Gene': 'DYDC2', 'p_SMR_multi': 2.180106e-07, 'p_HEIDI': 0.01238286, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_572629', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1124 | Q67 | What is the top-associated SNP of the gene C7orf59 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for C7orf59 in Whole Brain meta-analysis mQTL omic data for AD is rs60458236, which has a multi-SNP SMR p-value of 3.31e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C7orf59" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_74040', 'topRSID': 'rs60458236', 'Disease': 'AD', 'Gene': 'C7orf59', 'p_SMR_multi': 3.313887e-09, 'p_HEIDI': 7.857328e-06, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.286 | Q67 | What is the top-associated SNP of the gene DGKQ in Cerebellum eQTL omic data for PD and is it functionally significant? | The top-associated SNP for DGKQ in Cerebellum eQTL omic data for PD is rs3733345, which has a multi-SNP SMR p-value of 1.62e-08 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DGKQ" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_19050', 'topRSID': 'rs3733345', 'Disease': 'PD', 'Gene': 'DGKQ', 'p_SMR_multi': 1.624405e-08, 'p_HEIDI': 0.02208212, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.817 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Whole Blood eQTL GTEx omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Whole Blood eQTL GTEx omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 2.14e-35 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1684935', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 2.140282e-35, 'p_HEIDI': 1.982077e-10, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1092 | Q67 | What is the top-associated SNP of the gene WDR27 in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene WDR27 in Whole Brain meta-analysis mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "WDR27" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_351764', 'topRSID': 'rs9396946', 'Disease': 'LBD', 'Gene': 'WDR27', 'p_SMR_multi': 0.07838911, 'p_HEIDI': 0.6048127, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.295 | Q67 | What is the top-associated SNP of the gene LRRC37A in Hippocampus eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A in Hippocampus eQTL omic data for PSP is rs7225002, which has a multi-SNP SMR p-value of 6.31e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%hippocampus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_33472', 'topRSID': 'rs7225002', 'Disease': 'PSP', 'Gene': 'LRRC37A', 'p_SMR_multi': 6.312069e-11, 'p_HEIDI': 2.169444e-07, 'Omic_tissue': 'Hippocampus', 'Omic_type': 'Hippocampus eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.761 | Q67 | What is the top-associated SNP of the gene RP11-521O16.2 in Prefrontal Cortex eQTL omic data for AD and is it functionally significant? | The top-associated SNP for RP11-521O16.2 in Prefrontal Cortex eQTL omic data for AD is rs77279236, which has a multi-SNP SMR p-value of 7.65e-07 and a HEIDI of 0.24, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-521O16.2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1196032', 'topRSID': 'rs77279236', 'Disease': 'AD', 'Gene': 'RP11-521O16.2', 'p_SMR_multi': 7.651473e-07, 'p_HEIDI': 0.2359738, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.633 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PD is rs62056790, which has a multi-SNP SMR p-value of 1.86e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948891', 'topRSID': 'rs62063271', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 6.382411e-15, 'p_HEIDI': 2.368028e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.930 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Tibial Nerve eQTL omic data for AD and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Tibial Nerve eQTL omic data for AD is rs199456, which has a multi-SNP SMR p-value of 2.02e-06 and a HEIDI of 0.35, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1291761', 'topRSID': 'rs199456', 'Disease': 'AD', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 2.024902e-06, 'p_HEIDI': 0.3465603, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1019 | Q67 | What is the top-associated SNP of the gene ACE in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for ACE in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs6504163, which has a multi-SNP SMR p-value of 9.73e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ACE" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1396839', 'topRSID': 'rs6504163', 'Disease': 'AD', 'Gene': 'ACE', 'p_SMR_multi': 9.73321e-09, 'p_HEIDI': 4.822616e-08, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance threshold... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.132 | Q67 | What is the top-associated SNP of the gene PSORS1C1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for PSORS1C1 in Whole Blood mQTL omic data for AD is rs3094197, which has a multi-SNP SMR p-value of 2.26e-06 and a HEIDI of 0.04, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PSORS1C1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_620729', 'topRSID': 'rs9501055', 'Disease': 'AD', 'Gene': 'PSORS1C1', 'p_SMR_multi': 5.485384e-08, 'p_HEIDI': 0.004858996, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1175 | Q67 | What is the top-associated SNP of the gene ANXA5 in Nucleus Accumbens Basal Ganglia omic data for PSP and is it functionally significant? | There are no SNPs within the gene ANXA5 in Nucleus Accumbens Basal Ganglia omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ANXA5" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1731208', 'topRSID': 'rs2306420', 'Disease': 'PSP', 'Gene': 'ANXA5', 'p_SMR_multi': 0.7775019, 'p_HEIDI': 0.1052537, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.327 | Q67 | What is the top-associated SNP of the gene RP11-259G18.3 in Cortex eQTL GTEx omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.3 in Cortex eQTL GTEx omic data for PD is rs199533, which has a multi-SNP SMR p-value of 1.46e-12 and a HEIDI of 0.05, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.3" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1262227', 'topRSID': 'rs199533', 'Disease': 'PD', 'Gene': 'RP11-259G18.3', 'p_SMR_multi': 1.45849e-12, 'p_HEIDI': 0.05243878, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL GTEx', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1279 | Q67 | What is the top-associated SNP of the gene CR1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for CR1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs679515, which has a multi-SNP SMR p-value of 2.09e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CR1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1389608', 'topRSID': 'rs679515', 'Disease': 'AD', 'Gene': 'CR1', 'p_SMR_multi': 2.085436e-15, 'p_HEIDI': 9.09245e-08, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance threshold ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1385 | Q67 | What is the top-associated SNP of the gene LCN12 in Amygdala eQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene LCN12 in Amygdala eQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LCN12" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%amygdala eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1601950', 'topRSID': 'rs10781527', 'Disease': 'LBD', 'Gene': 'LCN12', 'p_SMR_multi': 0.6332893, 'p_HEIDI': 0.3169066, 'Omic_tissue': 'Amygdala', 'Omic_type': 'Amygdala eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.951 | Q67 | What is the top-associated SNP of the gene PRSS36 in Cortex eQTL metaBrain omic data for PD and is it functionally significant? | The top-associated SNP for PRSS36 in Cortex eQTL metaBrain omic data for PD is rs55667375, which has a multi-SNP SMR p-value of 3.01e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PRSS36" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1140855', 'topRSID': 'rs55667375', 'Disease': 'PD', 'Gene': 'PRSS36', 'p_SMR_multi': 3.010464e-08, 'p_HEIDI': 2.584743e-05, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1867 | Q67 | What is the top-associated SNP of the gene TMEM259 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for TMEM259 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs2240160, which has a multi-SNP SMR p-value of 4.82e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TMEM259" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 10... | [{'UUID': 'NDD_SMR_genes_all_update_text_1397179', 'topRSID': 'rs2240160', 'Disease': 'AD', 'Gene': 'TMEM259', 'p_SMR_multi': 4.824267e-08, 'p_HEIDI': 1.681359e-05, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thre... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1372 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Hypothalamus eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Hypothalamus eQTL omic data for PD is rs199533, which has a multi-SNP SMR p-value of 3.33e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%hypothalamus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1462895', 'topRSID': 'rs199533', 'Disease': 'PD', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 3.33133e-11, 'p_HEIDI': 0.003829891, 'Omic_tissue': 'Hypothalamus', 'Omic_type': 'Hypothalamus eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1520 | Q67 | What is the top-associated SNP of the gene MAPK3 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for MAPK3 in Whole Blood mQTL omic data for AD is rs8061772, which has a multi-SNP SMR p-value of 1.58e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPK3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_577443', 'topRSID': 'rs8061772', 'Disease': 'AD', 'Gene': 'MAPK3', 'p_SMR_multi': 1.583699e-06, 'p_HEIDI': 0.0006288385, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.702 | Q67 | What is the top-associated SNP of the gene PILRA in Skeletal Muscle eQTL omic data for AD and is it functionally significant? | The top-associated SNP for PILRA in Skeletal Muscle eQTL omic data for AD is rs61735533, which has a multi-SNP SMR p-value of 9.11e-07 and a HEIDI of 0.18, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PILRA" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1340322', 'topRSID': 'rs61735533', 'Disease': 'AD', 'Gene': 'PILRA', 'p_SMR_multi': 9.106531e-07, 'p_HEIDI': 0.1786957, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.218 | Q67 | What is the top-associated SNP of the gene C6orf10 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for C6orf10 in Whole Blood mQTL omic data for AD is rs35265698, which has a multi-SNP SMR p-value of 1.11e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C6orf10" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_621662', 'topRSID': 'rs35265698', 'Disease': 'AD', 'Gene': 'C6orf10', 'p_SMR_multi': 2.929935e-08, 'p_HEIDI': 2.344082e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1043 | Q67 | What is the top-associated SNP of the gene FAM47E in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for FAM47E in Whole Brain meta-analysis mQTL omic data for PD is rs62303000, which has a multi-SNP SMR p-value of 2.36e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FAM47E" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_432138', 'topRSID': 'rs62303000', 'Disease': 'PD', 'Gene': 'FAM47E', 'p_SMR_multi': 2.362795e-06, 'p_HEIDI': 0.002473996, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1815 | Q67 | What is the top-associated SNP of the gene NOTCH4 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for NOTCH4 in Whole Blood mQTL omic data for AD is rs9271663, which has a multi-SNP SMR p-value of 2.19e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NOTCH4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_621620', 'topRSID': 'rs34562262', 'Disease': 'AD', 'Gene': 'NOTCH4', 'p_SMR_multi': 1.292283e-07, 'p_HEIDI': 0.003108897, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.161 | Q67 | What is the top-associated SNP of the gene GTSF1 in Prefrontal Cortex eQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene GTSF1 in Prefrontal Cortex eQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GTSF1" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1211082', 'topRSID': 'rs79783475', 'Disease': 'ALS', 'Gene': 'GTSF1', 'p_SMR_multi': 0.4585378, 'p_HEIDI': 0.2456064, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1059 | Q67 | What is the top-associated SNP of the gene APOE in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for APOE in Whole Brain meta-analysis mQTL omic data for AD is rs73050293, which has a multi-SNP SMR p-value of 3.93e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APOE" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_122464', 'topRSID': 'rs73050293', 'Disease': 'AD', 'Gene': 'APOE', 'p_SMR_multi': 3.931424e-14, 'p_HEIDI': 1.590816e-11, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1243 | Q67 | What is the top-associated SNP of the gene NFYA in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for NFYA in Whole Blood mQTL omic data for AD is rs62396353, which has a multi-SNP SMR p-value of 7.08e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NFYA" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_622639', 'topRSID': 'rs72856298', 'Disease': 'AD', 'Gene': 'NFYA', 'p_SMR_multi': 3.336665e-10, 'p_HEIDI': 1.123977e-10, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.641 | Q67 | What is the top-associated SNP of the gene PPP4C in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for PPP4C in Whole Blood eQTL eQTLgen omic data for AD is rs12596543, which has a multi-SNP SMR p-value of 1.45e-08 and a HEIDI of 0.22, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PPP4C" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1501442', 'topRSID': 'rs12596543', 'Disease': 'AD', 'Gene': 'PPP4C', 'p_SMR_multi': 1.445689e-08, 'p_HEIDI': 0.2202619, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.522 | Q67 | What is the top-associated SNP of the gene DCAKD in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene DCAKD in Whole Brain meta-analysis mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DCAKD" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_395726', 'topRSID': 'rs55897749', 'Disease': 'LBD', 'Gene': 'DCAKD', 'p_SMR_multi': 0.4177582, 'p_HEIDI': 0.5597701, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1624 | Q67 | What is the top-associated SNP of the gene NECAP1 in Whole Blood mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene NECAP1 in Whole Blood mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NECAP1" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_921148', 'topRSID': 'rs2231750', 'Disease': 'LBD', 'Gene': 'NECAP1', 'p_SMR_multi': 0.385215, 'p_HEIDI': 0.2677722, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1522 | Q67 | What is the top-associated SNP of the gene TRIM40 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for TRIM40 in Whole Blood mQTL omic data for AD is rs17184549, which has a multi-SNP SMR p-value of 1.44e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TRIM40" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_620281', 'topRSID': 'rs115938232', 'Disease': 'AD', 'Gene': 'TRIM40', 'p_SMR_multi': 3.571278e-07, 'p_HEIDI': 0.7820669, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_620283', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
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