uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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|---|---|---|---|---|---|---|---|---|
Q67.604 | Q67 | What is the top-associated SNP of the gene FAM47E in Cortex eQTL metaBrain omic data for PD and is it functionally significant? | The top-associated SNP for FAM47E in Cortex eQTL metaBrain omic data for PD is rs4859657, which has a multi-SNP SMR p-value of 4.94e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FAM47E" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1140433', 'topRSID': 'rs4859657', 'Disease': 'PD', 'Gene': 'FAM47E', 'p_SMR_multi': 4.944625e-07, 'p_HEIDI': 5.755268e-06, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.198 | Q67 | What is the top-associated SNP of the gene LINC01117 in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene LINC01117 in Whole Brain meta-analysis mQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LINC01117" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_514513', 'topRSID': 'rs11679256', 'Disease': 'PSP', 'Gene': 'LINC01117', 'p_SMR_multi': 0.1967511, 'p_HEIDI': 0.2009348, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_t... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1644 | Q67 | What is the top-associated SNP of the gene RP11-259G18.2 in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.2 in Whole Blood eQTL eQTLgen omic data for PD is rs2532233, which has a multi-SNP SMR p-value of 7.07e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1564786', 'topRSID': 'rs2532233', 'Disease': 'PD', 'Gene': 'RP11-259G18.2', 'p_SMR_multi': 7.067652e-15, 'p_HEIDI': 7.348686e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.961 | Q67 | What is the top-associated SNP of the gene ZSWIM7 in Cortex eQTL metaBrain omic data for PD and is it functionally significant? | The top-associated SNP for ZSWIM7 in Cortex eQTL metaBrain omic data for PD is rs2535614, which has a multi-SNP SMR p-value of 2.31e-06 and a HEIDI of 0.18, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZSWIM7" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1147084', 'topRSID': 'rs2535614', 'Disease': 'PD', 'Gene': 'ZSWIM7', 'p_SMR_multi': 2.313541e-06, 'p_HEIDI': 0.1814649, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.416 | Q67 | What is the top-associated SNP of the gene SNCA in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for SNCA in Whole Blood mQTL omic data for PD is rs2301134, which has a multi-SNP SMR p-value of 1.48e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SNCA" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_998609', 'topRSID': 'rs2301134', 'Disease': 'PD', 'Gene': 'SNCA', 'p_SMR_multi': 1.478211e-12, 'p_HEIDI': 1.830236e-18, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.99 | Q67 | What is the top-associated SNP of the gene RP11-259G18.3 in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.3 in Whole Blood eQTL eQTLgen omic data for PD is rs199439, which has a multi-SNP SMR p-value of 5.19e-16 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.3" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1564787', 'topRSID': 'rs199439', 'Disease': 'PD', 'Gene': 'RP11-259G18.3', 'p_SMR_multi': 5.193095e-16, 'p_HEIDI': 4.675871e-07, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.988 | Q67 | What is the top-associated SNP of the gene APOC2 in Nucleus Accumbens Basal Ganglia omic data for AD and is it functionally significant? | The top-associated SNP for APOC2 in Nucleus Accumbens Basal Ganglia omic data for AD is rs11669173, which has a multi-SNP SMR p-value of 1.21e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APOC2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1717664', 'topRSID': 'rs11669173', 'Disease': 'AD', 'Gene': 'APOC2', 'p_SMR_multi': 1.212744e-10, 'p_HEIDI': 2.940443e-06, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'association meets significance threshold but shows si... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.933 | Q67 | What is the top-associated SNP of the gene LRRC37A4P in Liver eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A4P in Liver eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 2.72e-18 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A4P" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%liver eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1478182', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 2.715656e-18, 'p_HEIDI': 3.611203e-19, 'Omic_tissue': 'Liver', 'Omic_type': 'Liver eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequilibr... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.159 | Q67 | What is the top-associated SNP of the gene NSFP1 in Skeletal Muscle eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for NSFP1 in Skeletal Muscle eQTL omic data for PSP is rs4792831, which has a multi-SNP SMR p-value of 1.68e-16 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NSFP1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1375935', 'topRSID': 'rs4792831', 'Disease': 'PSP', 'Gene': 'NSFP1', 'p_SMR_multi': 1.681578e-16, 'p_HEIDI': 7.767569999999999e-27, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs of lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.425 | Q67 | What is the top-associated SNP of the gene TMCC2 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | There are no SNPs within the gene TMCC2 in Whole Blood eQTL eQTLgen omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TMCC2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1491123', 'topRSID': 'rs1668871', 'Disease': 'AD', 'Gene': 'TMCC2', 'p_SMR_multi': 0.01282296, 'p_HEIDI': 0.01582791, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1804 | Q67 | What is the top-associated SNP of the gene WBP1L in Whole Blood mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene WBP1L in Whole Blood mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "WBP1L" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_909756', 'topRSID': 'rs2244524', 'Disease': 'LBD', 'Gene': 'WBP1L', 'p_SMR_multi': 0.133632, 'p_HEIDI': 0.9163058, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_909757', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.483 | Q67 | What is the top-associated SNP of the gene ZNF232 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for ZNF232 in Whole Blood eQTL eQTLgen omic data for AD is rs55922100, which has a multi-SNP SMR p-value of 1.46e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZNF232" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1501927', 'topRSID': 'rs55922100', 'Disease': 'AD', 'Gene': 'ZNF232', 'p_SMR_multi': 1.45896e-07, 'p_HEIDI': 0.0001551816, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1512 | Q67 | What is the top-associated SNP of the gene ARFIP1 in Whole Brain eQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene ARFIP1 in Whole Brain eQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARFIP1" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1628783', 'topRSID': 'rs4504228', 'Disease': 'LBD', 'Gene': 'ARFIP1', 'p_SMR_multi': 0.9022221, 'p_HEIDI': 0.9818683, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.675 | Q67 | What is the top-associated SNP of the gene FAM155A in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene FAM155A in Whole Brain meta-analysis mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FAM155A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_100602', 'topRSID': 'rs2274040', 'Disease': 'AD', 'Gene': 'FAM155A', 'p_SMR_multi': 0.3848738, 'p_HEIDI': 0.2173588, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1238 | Q67 | What is the top-associated SNP of the gene TP73 in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene TP73 in Whole Brain meta-analysis mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TP73" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_317280', 'topRSID': 'rs12038064', 'Disease': 'LBD', 'Gene': 'TP73', 'p_SMR_multi': 0.1418711, 'p_HEIDI': 0.6021957, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_3... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1873 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for PD is rs17650872, which has a multi-SNP SMR p-value of 1.72e-13 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491114', 'topRSID': 'rs17652121', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 4.729064e-14, 'p_HEIDI': 0.04416005, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_49... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1299 | Q67 | What is the top-associated SNP of the gene NDUFAF6 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for NDUFAF6 in Whole Blood mQTL omic data for AD is rs6987752, which has a multi-SNP SMR p-value of 2.23e-06 and a HEIDI of 0.24, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NDUFAF6" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_616798', 'topRSID': 'rs1320164', 'Disease': 'AD', 'Gene': 'NDUFAF6', 'p_SMR_multi': 1.716817e-06, 'p_HEIDI': 0.2600196, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_616796', 'topRS... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.453 | Q67 | What is the top-associated SNP of the gene C6orf150 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene C6orf150 in Whole Brain meta-analysis mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C6orf150" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_67694', 'topRSID': 'rs9293930', 'Disease': 'AD', 'Gene': 'C6orf150', 'p_SMR_multi': 0.5308183, 'p_HEIDI': 0.8589091, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.559 | Q67 | What is the top-associated SNP of the gene CRHR1-IT1 in Nucleus Accumbens Basal Ganglia omic data for PSP and is it functionally significant? | The top-associated SNP for CRHR1-IT1 in Nucleus Accumbens Basal Ganglia omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 3.08e-18 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1-IT1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1732393', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'CRHR1-IT1', 'p_SMR_multi': 3.0832270000000002e-18, 'p_HEIDI': 7.416239e-21, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'association meets significance threshol... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.181 | Q67 | What is the top-associated SNP of the gene ZNF668 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for ZNF668 in Whole Blood eQTL eQTLgen omic data for AD is rs2303222, which has a multi-SNP SMR p-value of 8.05e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZNF668" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1501476', 'topRSID': 'rs2303222', 'Disease': 'AD', 'Gene': 'ZNF668', 'p_SMR_multi': 8.050569e-08, 'p_HEIDI': 0.002467109, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.396 | Q67 | What is the top-associated SNP of the gene TAP2 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for TAP2 in Whole Blood mQTL omic data for AD is rs241437, which has a multi-SNP SMR p-value of 8.32e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TAP2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_621739', 'topRSID': 'rs241437', 'Disease': 'AD', 'Gene': 'TAP2', 'p_SMR_multi': 8.321216e-09, 'p_HEIDI': 0.003695236, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequil... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.584 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Tibial Nerve eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Tibial Nerve eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 3.87e-32 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1336291', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 3.868354e-32, 'p_HEIDI': 5.934329e-11, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.995 | Q67 | What is the top-associated SNP of the gene FAM215B in Cerebellum eQTL omic data for PD and is it functionally significant? | The top-associated SNP for FAM215B in Cerebellum eQTL omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 1.45e-10 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FAM215B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1710359', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'FAM215B', 'p_SMR_multi': 1.449976e-10, 'p_HEIDI': 0.01393696, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1707 | Q67 | What is the top-associated SNP of the gene BTNL2 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for BTNL2 in Whole Blood mQTL omic data for AD is rs115625939, which has a multi-SNP SMR p-value of 3.11e-07 and a HEIDI of 0.15, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "BTNL2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_621688', 'topRSID': 'rs116522341', 'Disease': 'AD', 'Gene': 'BTNL2', 'p_SMR_multi': 2.681311e-09, 'p_HEIDI': 2.28461e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1285 | Q67 | What is the top-associated SNP of the gene CLU in Skeletal Muscle eQTL omic data for AD and is it functionally significant? | The top-associated SNP for CLU in Skeletal Muscle eQTL omic data for AD is rs2070926, which has a multi-SNP SMR p-value of 4.31e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CLU" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1340523', 'topRSID': 'rs2070926', 'Disease': 'AD', 'Gene': 'CLU', 'p_SMR_multi': 4.31469e-08, 'p_HEIDI': 0.0007744253, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1645 | Q67 | What is the top-associated SNP of the gene AC074212.5 in Whole Brain meta-analysis mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene AC074212.5 in Whole Brain meta-analysis mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AC074212.5" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_218490', 'topRSID': 'rs635299', 'Disease': 'ALS', 'Gene': 'AC074212.5', 'p_SMR_multi': 0.2846865, 'p_HEIDI': 0.6878237, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_te... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.886 | Q67 | What is the top-associated SNP of the gene ADCY10P1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for ADCY10P1 in Whole Blood mQTL omic data for AD is rs78609059, which has a multi-SNP SMR p-value of 3.61e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ADCY10P1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_622643', 'topRSID': 'rs78609059', 'Disease': 'AD', 'Gene': 'ADCY10P1', 'p_SMR_multi': 3.61254e-08, 'p_HEIDI': 8.750358e-10, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.827 | Q67 | What is the top-associated SNP of the gene IGSF9B in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for IGSF9B in Whole Brain meta-analysis mQTL omic data for PD is rs11223627, which has a multi-SNP SMR p-value of 9.43e-07 and a HEIDI of 0.05, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IGSF9B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_470339', 'topRSID': 'rs1793680', 'Disease': 'PD', 'Gene': 'IGSF9B', 'p_SMR_multi': 2.071103e-10, 'p_HEIDI': 0.006061729, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1660 | Q67 | What is the top-associated SNP of the gene BTNL2 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for BTNL2 in Whole Blood mQTL omic data for AD is rs17191234, which has a multi-SNP SMR p-value of 1.57e-07 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "BTNL2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_621688', 'topRSID': 'rs116522341', 'Disease': 'AD', 'Gene': 'BTNL2', 'p_SMR_multi': 2.681311e-09, 'p_HEIDI': 2.28461e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.972 | Q67 | What is the top-associated SNP of the gene GAL3ST4 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for GAL3ST4 in Whole Blood eQTL eQTLgen omic data for AD is rs11764176, which has a multi-SNP SMR p-value of 4.26e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GAL3ST4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1495798', 'topRSID': 'rs11764176', 'Disease': 'AD', 'Gene': 'GAL3ST4', 'p_SMR_multi': 4.262207e-11, 'p_HEIDI': 1.707258e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ L... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1049 | Q67 | What is the top-associated SNP of the gene MAPK3 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for MAPK3 in Whole Blood eQTL eQTLgen omic data for AD is rs55732507, which has a multi-SNP SMR p-value of 2.60e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPK3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1501448', 'topRSID': 'rs55732507', 'Disease': 'AD', 'Gene': 'MAPK3', 'p_SMR_multi': 2.599191e-11, 'p_HEIDI': 6.350792e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.671 | Q67 | What is the top-associated SNP of the gene FOXRED1 in Whole Blood eQTL GTEx omic data for PSP and is it functionally significant? | There are no SNPs within the gene FOXRED1 in Whole Blood eQTL GTEx omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FOXRED1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1683814', 'topRSID': 'rs478309', 'Disease': 'PSP', 'Gene': 'FOXRED1', 'p_SMR_multi': 0.655197, 'p_HEIDI': 0.5331422, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.145 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 7.36e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041740', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'MAPT', 'p_SMR_multi': 3.1929999999999995e-44, 'p_HEIDI': 3.11336e-12, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1518 | Q67 | What is the top-associated SNP of the gene CD38 in Nucleus Accumbens Basal Ganglia omic data for PD and is it functionally significant? | The top-associated SNP for CD38 in Nucleus Accumbens Basal Ganglia omic data for PD is rs4698413, which has a multi-SNP SMR p-value of 4.31e-07 and a HEIDI of 0.45, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CD38" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1728225', 'topRSID': 'rs4698413', 'Disease': 'PD', 'Gene': 'CD38', 'p_SMR_multi': 4.311773e-07, 'p_HEIDI': 0.4461342, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1999 | Q67 | What is the top-associated SNP of the gene EPT1 in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene EPT1 in Whole Brain meta-analysis mQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "EPT1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_512177', 'topRSID': 'rs7565734', 'Disease': 'PSP', 'Gene': 'EPT1', 'p_SMR_multi': 0.2603071, 'p_HEIDI': 0.05782274, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_5... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.871 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Hypothalamus eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Hypothalamus eQTL omic data for PD is rs8073146, which has a multi-SNP SMR p-value of 6.70e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%hypothalamus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1462902', 'topRSID': 'rs8073146', 'Disease': 'PD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 6.70296e-12, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Hypothalamus', 'Omic_type': 'Hypothalamus eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.427 | Q67 | What is the top-associated SNP of the gene CRHR1-IT1 in Cerebellar Hemisphere eQTL omic data for PD and is it functionally significant? | The top-associated SNP for CRHR1-IT1 in Cerebellar Hemisphere eQTL omic data for PD is rs17652520, which has a multi-SNP SMR p-value of 1.47e-07 and a HEIDI of 0.15, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1-IT1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1191169', 'topRSID': 'rs17652520', 'Disease': 'PD', 'Gene': 'CRHR1-IT1', 'p_SMR_multi': 1.471046e-07, 'p_HEIDI': 0.1452017, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.643 | Q67 | What is the top-associated SNP of the gene PSMC3 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for PSMC3 in Whole Brain meta-analysis mQTL omic data for AD is rs7104036, which has a multi-SNP SMR p-value of 7.70e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PSMC3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_91158', 'topRSID': 'rs7104036', 'Disease': 'AD', 'Gene': 'PSMC3', 'p_SMR_multi': 7.701278e-08, 'p_HEIDI': 0.0005235828, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1408 | Q67 | What is the top-associated SNP of the gene RP11-707O23.5 in Tibial Nerve eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-707O23.5 in Tibial Nerve eQTL omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 6.86e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-707O23.5" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1328928', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'RP11-707O23.5', 'p_SMR_multi': 6.856036e-15, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.806 | Q67 | What is the top-associated SNP of the gene C7orf43 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for C7orf43 in Whole Blood eQTL eQTLgen omic data for AD is rs6975031, which has a multi-SNP SMR p-value of 1.99e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C7orf43" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1495797', 'topRSID': 'rs6975031', 'Disease': 'AD', 'Gene': 'C7orf43', 'p_SMR_multi': 1.991609e-09, 'p_HEIDI': 4.003791e-07, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1067 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Blood eQTL eQTLgen omic data for AD is rs12951057, which has a multi-SNP SMR p-value of 2.40e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1502448', 'topRSID': 'rs12951057', 'Disease': 'AD', 'Gene': 'KANSL1', 'p_SMR_multi': 2.401427e-06, 'p_HEIDI': 2.044173e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.622 | Q67 | What is the top-associated SNP of the gene MMRN1 in Hippocampus eQTL omic data for PD and is it functionally significant? | The top-associated SNP for MMRN1 in Hippocampus eQTL omic data for PD is rs79994234, which has a multi-SNP SMR p-value of 9.05e-08 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MMRN1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%hippocampus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1385772', 'topRSID': 'rs79994234', 'Disease': 'PD', 'Gene': 'MMRN1', 'p_SMR_multi': 9.052398e-08, 'p_HEIDI': 0.01362235, 'Omic_tissue': 'Hippocampus', 'Omic_type': 'Hippocampus eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.298 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Blood mQTL omic data for PD is rs2959950, which has a multi-SNP SMR p-value of 2.50e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948846', 'topRSID': 'rs35489312', 'Disease': 'PD', 'Gene': 'ARHGAP27', 'p_SMR_multi': 3.386602e-15, 'p_HEIDI': 0.001263654, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.912 | Q67 | What is the top-associated SNP of the gene SNCA in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | The top-associated SNP for SNCA in Whole Brain meta-analysis mQTL omic data for LBD is rs6817026, which has a multi-SNP SMR p-value of 2.74e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SNCA" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_338827', 'topRSID': 'rs3756059', 'Disease': 'LBD', 'Gene': 'SNCA', 'p_SMR_multi': 4.824404e-10, 'p_HEIDI': 0.0002321407, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.917 | Q67 | What is the top-associated SNP of the gene LRRC37A in Hippocampus eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A in Hippocampus eQTL omic data for PD is rs2696466, which has a multi-SNP SMR p-value of 1.75e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%hippocampus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_33015', 'topRSID': 'rs2696466', 'Disease': 'PD', 'Gene': 'LRRC37A', 'p_SMR_multi': 1.74889e-08, 'p_HEIDI': 7.12884e-05, 'Omic_tissue': 'Hippocampus', 'Omic_type': 'Hippocampus eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1903 | Q67 | What is the top-associated SNP of the gene ZNF713 in Skeletal Muscle eQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene ZNF713 in Skeletal Muscle eQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZNF713" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1340200', 'topRSID': 'rs73132888', 'Disease': 'AD', 'Gene': 'ZNF713', 'p_SMR_multi': 0.4091976, 'p_HEIDI': 0.1982762, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.91 | Q67 | What is the top-associated SNP of the gene TNPO1 in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | There are no SNPs within the gene TNPO1 in Whole Blood eQTL eQTLgen omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TNPO1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1556390', 'topRSID': 'rs1364076', 'Disease': 'PD', 'Gene': 'TNPO1', 'p_SMR_multi': 0.3798398, 'p_HEIDI': 0.8890479, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.42 | Q67 | What is the top-associated SNP of the gene Y_RNA in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for Y_RNA in Whole Blood eQTL eQTLgen omic data for AD is rs114202986, which has a multi-SNP SMR p-value of 2.22e-06 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "Y_RNA" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1494722', 'topRSID': 'rs114202986', 'Disease': 'AD', 'Gene': 'Y_RNA', 'p_SMR_multi': 2.22355e-06, 'p_HEIDI': 0.01721355, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_150129... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1803 | Q67 | What is the top-associated SNP of the gene UCP1 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene UCP1 in Whole Brain meta-analysis mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "UCP1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_57094', 'topRSID': 'rs59036305', 'Disease': 'AD', 'Gene': 'UCP1', 'p_SMR_multi': 0.5156742, 'p_HEIDI': 0.749074, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_5709... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1934 | Q67 | What is the top-associated SNP of the gene RP5-1142A6.2 in Whole Brain eQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene RP5-1142A6.2 in Whole Brain eQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP5-1142A6.2" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1618029', 'topRSID': 'rs8050504', 'Disease': 'ALS', 'Gene': 'RP5-1142A6.2', 'p_SMR_multi': 0.04763002, 'p_HEIDI': 0.2068054, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.134 | Q67 | What is the top-associated SNP of the gene MMRN1 in Amygdala eQTL omic data for PD and is it functionally significant? | The top-associated SNP for MMRN1 in Amygdala eQTL omic data for PD is rs116370523, which has a multi-SNP SMR p-value of 4.47e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MMRN1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%amygdala eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1602983', 'topRSID': 'rs116370523', 'Disease': 'PD', 'Gene': 'MMRN1', 'p_SMR_multi': 4.468223e-07, 'p_HEIDI': 0.0007666944, 'Omic_tissue': 'Amygdala', 'Omic_type': 'Amygdala eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequil... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1566 | Q67 | What is the top-associated SNP of the gene SRCAP in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for SRCAP in Whole Blood mQTL omic data for PD is rs3747481, which has a multi-SNP SMR p-value of 1.15e-06 and a HEIDI of 0.03, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SRCAP" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_974653', 'topRSID': 'rs3747481', 'Disease': 'PD', 'Gene': 'SRCAP', 'p_SMR_multi': 1.154869e-06, 'p_HEIDI': 0.02508775, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_974652', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.977 | Q67 | What is the top-associated SNP of the gene ARL17A in Amygdala eQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARL17A in Amygdala eQTL omic data for PD is rs8073146, which has a multi-SNP SMR p-value of 3.10e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%amygdala eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1603783', 'topRSID': 'rs8073146', 'Disease': 'PD', 'Gene': 'ARL17A', 'p_SMR_multi': 3.096916e-07, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Amygdala', 'Omic_type': 'Amygdala eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1070 | Q67 | What is the top-associated SNP of the gene DISP2 in Cortex eQTL GTEx omic data for FTD and is it functionally significant? | There are no SNPs within the gene DISP2 in Cortex eQTL GTEx omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DISP2" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%cortex eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1254226', 'topRSID': 'rs71472433', 'Disease': 'FTD', 'Gene': 'DISP2', 'p_SMR_multi': 0.1112224, 'p_HEIDI': 0.6083161, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL GTEx', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1856 | Q67 | What is the top-associated SNP of the gene FAM57B in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for FAM57B in Whole Brain meta-analysis mQTL omic data for AD is rs4788213, which has a multi-SNP SMR p-value of 5.65e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FAM57B" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_109463', 'topRSID': 'rs4788213', 'Disease': 'AD', 'Gene': 'FAM57B', 'p_SMR_multi': 5.648017e-07, 'p_HEIDI': 0.004797759, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1346 | Q67 | What is the top-associated SNP of the gene VKORC1 in Whole Brain meta-analysis mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene VKORC1 in Whole Brain meta-analysis mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "VKORC1" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_297612', 'topRSID': 'rs2884737', 'Disease': 'FTD', 'Gene': 'VKORC1', 'p_SMR_multi': 0.1367858, 'p_HEIDI': 0.5341676, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1831 | Q67 | What is the top-associated SNP of the gene KLHL7-AS1 in Cortex eQTL GTEx omic data for PD and is it functionally significant? | The top-associated SNP for KLHL7-AS1 in Cortex eQTL GTEx omic data for PD is rs4409314, which has a multi-SNP SMR p-value of 2.02e-07 and a HEIDI of 0.08, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KLHL7-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1260545', 'topRSID': 'rs4409314', 'Disease': 'PD', 'Gene': 'KLHL7-AS1', 'p_SMR_multi': 2.024731e-07, 'p_HEIDI': 0.07704355, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL GTEx', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.167 | Q67 | What is the top-associated SNP of the gene DND1P1 in Hypothalamus eQTL omic data for PD and is it functionally significant? | The top-associated SNP for DND1P1 in Hypothalamus eQTL omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 1.98e-10 and a HEIDI of 0.85, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DND1P1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%hypothalamus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1462890', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'DND1P1', 'p_SMR_multi': 1.9788e-10, 'p_HEIDI': 0.852796, 'Omic_tissue': 'Hypothalamus', 'Omic_type': 'Hypothalamus eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.731 | Q67 | What is the top-associated SNP of the gene DPCR1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for DPCR1 in Whole Blood mQTL omic data for AD is rs2233980, which has a multi-SNP SMR p-value of 5.38e-08 and a HEIDI of 0.04, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DPCR1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_620628', 'topRSID': 'rs2233980', 'Disease': 'AD', 'Gene': 'DPCR1', 'p_SMR_multi': 5.375279e-08, 'p_HEIDI': 0.03561558, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_620629', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.294 | Q67 | What is the top-associated SNP of the gene FMNL1 in Cerebellum eQTL omic data for PD and is it functionally significant? | The top-associated SNP for FMNL1 in Cerebellum eQTL omic data for PD is rs12150464, which has a multi-SNP SMR p-value of 2.16e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FMNL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1710337', 'topRSID': 'rs62063276', 'Disease': 'PD', 'Gene': 'FMNL1', 'p_SMR_multi': 1.14186e-10, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequilibr... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1142 | Q67 | What is the top-associated SNP of the gene RP11-259G18.1 in Amygdala eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.1 in Amygdala eQTL omic data for PD is rs112411928, which has a multi-SNP SMR p-value of 3.79e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%amygdala eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1603779', 'topRSID': 'rs112411928', 'Disease': 'PD', 'Gene': 'RP11-259G18.1', 'p_SMR_multi': 3.789212e-08, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Amygdala', 'Omic_type': 'Amygdala eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1536 | Q67 | What is the top-associated SNP of the gene DIEXF in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene DIEXF in Whole Brain meta-analysis mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DIEXF" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_417220', 'topRSID': 'rs960339', 'Disease': 'PD', 'Gene': 'DIEXF', 'p_SMR_multi': 0.4513241, 'p_HEIDI': 0.2815422, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_417... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1897 | Q67 | What is the top-associated SNP of the gene C9orf72 in Putamen Basal Ganglia eQTL omic data for ALS and is it functionally significant? | The top-associated SNP for C9orf72 in Putamen Basal Ganglia eQTL omic data for ALS is rs774358, which has a multi-SNP SMR p-value of 9.77e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C9orf72" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1586101', 'topRSID': 'rs774358', 'Disease': 'ALS', 'Gene': 'C9orf72', 'p_SMR_multi': 9.771533e-07, 'p_HEIDI': 0.001766621, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs of ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1006 | Q67 | What is the top-associated SNP of the gene RP11-798G7.8 in Liver eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-798G7.8 in Liver eQTL omic data for PSP is rs11869096, which has a multi-SNP SMR p-value of 3.85e-07 and a HEIDI of 0.03, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-798G7.8" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%liver eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1478183', 'topRSID': 'rs11869096', 'Disease': 'PSP', 'Gene': 'RP11-798G7.8', 'p_SMR_multi': 3.852944e-07, 'p_HEIDI': 0.02869639, 'Omic_tissue': 'Liver', 'Omic_type': 'Liver eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1421 | Q67 | What is the top-associated SNP of the gene RP11-259G18.1 in Caudate Basal Ganglia eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.1 in Caudate Basal Ganglia eQTL omic data for PSP is rs1635291, which has a multi-SNP SMR p-value of 1.11e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1283706', 'topRSID': 'rs1635291', 'Disease': 'PSP', 'Gene': 'RP11-259G18.1', 'p_SMR_multi': 1.111834e-13, 'p_HEIDI': 2.538554e-07, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows s... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.785 | Q67 | What is the top-associated SNP of the gene MMRN1 in Cortex eQTL metaBrain omic data for PD and is it functionally significant? | The top-associated SNP for MMRN1 in Cortex eQTL metaBrain omic data for PD is rs112334424, which has a multi-SNP SMR p-value of 4.10e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MMRN1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1140477', 'topRSID': 'rs112334424', 'Disease': 'PD', 'Gene': 'MMRN1', 'p_SMR_multi': 4.097178e-14, 'p_HEIDI': 2.698835e-06, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.846 | Q67 | What is the top-associated SNP of the gene RP11-259G18.3 in Anterior Cingulate Cortex BA24 eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.3 in Anterior Cingulate Cortex BA24 eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 4.72e-17 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.3" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%anterior cingulate cortex ba24 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1489540', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'RP11-259G18.3', 'p_SMR_multi': 4.7246440000000004e-17, 'p_HEIDI': 2.441354e-10, 'Omic_tissue': 'Anterior Cingulate Cortex BA24', 'Omic_type': 'Anterior Cingulate Cortex BA24 eQTL', 'func_sig': 'association meets signifi... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.352 | Q67 | What is the top-associated SNP of the gene FCER1G in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for FCER1G in Whole Blood eQTL eQTLgen omic data for AD is rs2070901, which has a multi-SNP SMR p-value of 2.26e-09 and a HEIDI of 0.03, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FCER1G" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1490908', 'topRSID': 'rs2070901', 'Disease': 'AD', 'Gene': 'FCER1G', 'p_SMR_multi': 2.258228e-09, 'p_HEIDI': 0.02754168, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1945 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for PD is rs17574361, which has a multi-SNP SMR p-value of 2.72e-13 and a HEIDI of 0.06, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491114', 'topRSID': 'rs17652121', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 4.729064e-14, 'p_HEIDI': 0.04416005, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_49... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.577 | Q67 | What is the top-associated SNP of the gene NSFP1 in Putamen Basal Ganglia eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for NSFP1 in Putamen Basal Ganglia eQTL omic data for PSP is rs17692129, which has a multi-SNP SMR p-value of 1.45e-11 and a HEIDI of 0.4, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NSFP1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1596828', 'topRSID': 'rs17692129', 'Disease': 'PSP', 'Gene': 'NSFP1', 'p_SMR_multi': 1.446027e-11, 'p_HEIDI': 0.3950962, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1923 | Q67 | What is the top-associated SNP of the gene RP11-798G7.6 in Whole Blood eQTL GTEx omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-798G7.6 in Whole Blood eQTL GTEx omic data for PSP is rs7220988, which has a multi-SNP SMR p-value of 8.96e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-798G7.6" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1684930', 'topRSID': 'rs7220988', 'Disease': 'PSP', 'Gene': 'RP11-798G7.6', 'p_SMR_multi': 8.960125e-07, 'p_HEIDI': 0.0001082747, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1888 | Q67 | What is the top-associated SNP of the gene PSMC3 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for PSMC3 in Whole Blood mQTL omic data for AD is rs12292911, which has a multi-SNP SMR p-value of 2.56e-07 and a HEIDI of 0.46, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PSMC3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_608490', 'topRSID': 'rs12292911', 'Disease': 'AD', 'Gene': 'PSMC3', 'p_SMR_multi': 2.558536e-07, 'p_HEIDI': 0.463588, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_608492', 'topRSID... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1470 | Q67 | What is the top-associated SNP of the gene DOC2A in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for DOC2A in Whole Blood mQTL omic data for AD is rs12596543, which has a multi-SNP SMR p-value of 2.06e-08 and a HEIDI of 0.27, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DOC2A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_577418', 'topRSID': 'rs12921753', 'Disease': 'AD', 'Gene': 'DOC2A', 'p_SMR_multi': 5.575261e-12, 'p_HEIDI': 0.3441697, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_577427', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1818 | Q67 | What is the top-associated SNP of the gene CRHR1 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for CRHR1 in Whole Blood mQTL omic data for PD is rs112746008, which has a multi-SNP SMR p-value of 2.74e-13 and a HEIDI of 0.06, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948861', 'topRSID': 'rs17689882', 'Disease': 'PD', 'Gene': 'CRHR1', 'p_SMR_multi': 8.633399e-15, 'p_HEIDI': 7.397796e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1317 | Q67 | What is the top-associated SNP of the gene RP11-259G18.1 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.1 in Whole Brain meta-analysis mQTL omic data for PD is rs554899842, which has a multi-SNP SMR p-value of 5.60e-13 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491164', 'topRSID': 'rs554899842', 'Disease': 'PD', 'Gene': 'RP11-259G18.1', 'p_SMR_multi': 5.604857e-13, 'p_HEIDI': 0.01086052, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_upda... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1501 | Q67 | What is the top-associated SNP of the gene GRIN3B in Tibial Nerve eQTL omic data for AD and is it functionally significant? | The top-associated SNP for GRIN3B in Tibial Nerve eQTL omic data for AD is rs10401454, which has a multi-SNP SMR p-value of 4.16e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GRIN3B" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1292157', 'topRSID': 'rs10401454', 'Disease': 'AD', 'Gene': 'GRIN3B', 'p_SMR_multi': 4.157801e-07, 'p_HEIDI': 0.0001457089, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.464 | Q67 | What is the top-associated SNP of the gene BTBD9 in Whole Blood mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene BTBD9 in Whole Blood mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "BTBD9" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_622545', 'topRSID': 'rs9349063', 'Disease': 'AD', 'Gene': 'BTBD9', 'p_SMR_multi': 0.1993461, 'p_HEIDI': 0.1731884, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_622546', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.381 | Q67 | What is the top-associated SNP of the gene SNCA in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for SNCA in Whole Blood mQTL omic data for PD is rs1372520, which has a multi-SNP SMR p-value of 6.05e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SNCA" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_998609', 'topRSID': 'rs2301134', 'Disease': 'PD', 'Gene': 'SNCA', 'p_SMR_multi': 1.478211e-12, 'p_HEIDI': 1.830236e-18, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1344 | Q67 | What is the top-associated SNP of the gene ARL17B in Cerebellum eQTL omic data for AD and is it functionally significant? | The top-associated SNP for ARL17B in Cerebellum eQTL omic data for AD is rs7225002, which has a multi-SNP SMR p-value of 4.20e-07 and a HEIDI of 0.59, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17B" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_2659', 'topRSID': 'rs7225002', 'Disease': 'AD', 'Gene': 'ARL17B', 'p_SMR_multi': 4.203789e-07, 'p_HEIDI': 0.5937533, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1690050', 'topRSID':... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.337 | Q67 | What is the top-associated SNP of the gene CRHR1 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for CRHR1 in Whole Blood mQTL omic data for PD is rs113790915, which has a multi-SNP SMR p-value of 1.26e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948861', 'topRSID': 'rs17689882', 'Disease': 'PD', 'Gene': 'CRHR1', 'p_SMR_multi': 8.633399e-15, 'p_HEIDI': 7.397796e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1284 | Q67 | What is the top-associated SNP of the gene DND1P1 in Hippocampus eQTL omic data for PD and is it functionally significant? | The top-associated SNP for DND1P1 in Hippocampus eQTL omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 2.16e-10 and a HEIDI of 0.87, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DND1P1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%hippocampus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1386988', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'DND1P1', 'p_SMR_multi': 2.161785e-10, 'p_HEIDI': 0.8692197, 'Omic_tissue': 'Hippocampus', 'Omic_type': 'Hippocampus eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1762 | Q67 | What is the top-associated SNP of the gene CEACAM19 in Hippocampus eQTL omic data for AD and is it functionally significant? | The top-associated SNP for CEACAM19 in Hippocampus eQTL omic data for AD is rs56261258, which has a multi-SNP SMR p-value of 2.37e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CEACAM19" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%hippocampus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1378751', 'topRSID': 'rs56261258', 'Disease': 'AD', 'Gene': 'CEACAM19', 'p_SMR_multi': 2.368238e-07, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Hippocampus', 'Omic_type': 'Hippocampus eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1459 | Q67 | What is the top-associated SNP of the gene WNT3 in Skeletal Muscle eQTL omic data for PD and is it functionally significant? | The top-associated SNP for WNT3 in Skeletal Muscle eQTL omic data for PD is rs199523, which has a multi-SNP SMR p-value of 8.52e-07 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "WNT3" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1370555', 'topRSID': 'rs199523', 'Disease': 'PD', 'Gene': 'WNT3', 'p_SMR_multi': 8.522662e-07, 'p_HEIDI': 0.01487822, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.823 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Blood mQTL omic data for PD is rs199525, which has a multi-SNP SMR p-value of 1.58e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948907', 'topRSID': 'rs2532233', 'Disease': 'PD', 'Gene': 'KANSL1', 'p_SMR_multi': 1.024112e-14, 'p_HEIDI': 2.989456e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1114 | Q67 | What is the top-associated SNP of the gene RP11-78B10.2 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for RP11-78B10.2 in Whole Blood eQTL eQTLgen omic data for AD is rs6672474, which has a multi-SNP SMR p-value of 1.99e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-78B10.2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1491153', 'topRSID': 'rs6672474', 'Disease': 'AD', 'Gene': 'RP11-78B10.2', 'p_SMR_multi': 1.988645e-07, 'p_HEIDI': 1.068048e-15, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1524 | Q67 | What is the top-associated SNP of the gene PTPRN2 in Whole Blood mQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene PTPRN2 in Whole Blood mQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PTPRN2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1050805', 'topRSID': 'rs6961856', 'Disease': 'PSP', 'Gene': 'PTPRN2', 'p_SMR_multi': 0.01752929, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1050808', 'top... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1941 | Q67 | What is the top-associated SNP of the gene OARD1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for OARD1 in Whole Blood mQTL omic data for AD is rs9394755, which has a multi-SNP SMR p-value of 4.27e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "OARD1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_622631', 'topRSID': 'rs4714423', 'Disease': 'AD', 'Gene': 'OARD1', 'p_SMR_multi': 7.881563e-08, 'p_HEIDI': 0.0007337849, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1616 | Q67 | What is the top-associated SNP of the gene ITGAX in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for ITGAX in Whole Blood eQTL eQTLgen omic data for AD is rs11574631, which has a multi-SNP SMR p-value of 3.17e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ITGAX" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1501486', 'topRSID': 'rs11574631', 'Disease': 'AD', 'Gene': 'ITGAX', 'p_SMR_multi': 3.173201e-08, 'p_HEIDI': 0.0003262819, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1898 | Q67 | What is the top-associated SNP of the gene LRRC37A4P in Hypothalamus eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A4P in Hypothalamus eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 1.46e-18 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A4P" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%hypothalamus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1464413', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 1.457153e-18, 'p_HEIDI': 5.3666859999999995e-20, 'Omic_tissue': 'Hypothalamus', 'Omic_type': 'Hypothalamus eQTL', 'func_sig': 'association meets significance threshold but shows signs of link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.918 | Q67 | What is the top-associated SNP of the gene CD2AP in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CD2AP in Whole Blood mQTL omic data for AD is rs13212790, which has a multi-SNP SMR p-value of 1.45e-07 and a HEIDI of 0.09, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CD2AP" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_622985', 'topRSID': 'rs13193054', 'Disease': 'AD', 'Gene': 'CD2AP', 'p_SMR_multi': 2.598285e-09, 'p_HEIDI': 0.05195758, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_622988', 'topRS... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1930 | Q67 | What is the top-associated SNP of the gene LAMTOR4 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for LAMTOR4 in Whole Brain meta-analysis mQTL omic data for AD is rs12878, which has a multi-SNP SMR p-value of 1.45e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LAMTOR4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_74041', 'topRSID': 'rs12878', 'Disease': 'AD', 'Gene': 'LAMTOR4', 'p_SMR_multi': 1.445543e-06, 'p_HEIDI': 0.0002676306, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1126 | Q67 | What is the top-associated SNP of the gene CRHR1 in Prefrontal Cortex eQTL omic data for PD and is it functionally significant? | The top-associated SNP for CRHR1 in Prefrontal Cortex eQTL omic data for PD is rs567299266, which has a multi-SNP SMR p-value of 1.59e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1242271', 'topRSID': 'rs567299266', 'Disease': 'PD', 'Gene': 'CRHR1', 'p_SMR_multi': 1.592654e-12, 'p_HEIDI': 0.003493543, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.332 | Q67 | What is the top-associated SNP of the gene KAT8 in Whole Brain eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KAT8 in Whole Brain eQTL omic data for PD is rs12597511, which has a multi-SNP SMR p-value of 1.84e-07 and a HEIDI of 0.05, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KAT8" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1639764', 'topRSID': 'rs12597511', 'Disease': 'PD', 'Gene': 'KAT8', 'p_SMR_multi': 1.841304e-07, 'p_HEIDI': 0.04586272, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1036 | Q67 | What is the top-associated SNP of the gene RP11-259G18.2 in Frontal Cortex BA9 eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.2 in Frontal Cortex BA9 eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 9.06e-16 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%frontal cortex ba9 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1170874', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'RP11-259G18.2', 'p_SMR_multi': 9.064537e-16, 'p_HEIDI': 1.617579e-12, 'Omic_tissue': 'Frontal Cortex', 'Omic_type': 'Frontal Cortex BA9 eQTL', 'func_sig': 'association meets significance threshold but shows signs of lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.322 | Q67 | What is the top-associated SNP of the gene RP11-707O23.5 in Cerebellar Hemisphere eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-707O23.5 in Cerebellar Hemisphere eQTL omic data for PD is rs8073146, which has a multi-SNP SMR p-value of 4.06e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-707O23.5" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1191168', 'topRSID': 'rs8073146', 'Disease': 'PD', 'Gene': 'RP11-707O23.5', 'p_SMR_multi': 4.057024e-11, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'association meets significance threshold but shows signs o... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1531 | Q67 | What is the top-associated SNP of the gene POMZP3 in Putamen Basal Ganglia eQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene POMZP3 in Putamen Basal Ganglia eQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "POMZP3" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1585908', 'topRSID': 'rs41278779', 'Disease': 'ALS', 'Gene': 'POMZP3', 'p_SMR_multi': 0.07495616, 'p_HEIDI': 0.5676206, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1360 | Q67 | What is the top-associated SNP of the gene ARL17A in Cortex eQTL GTEx omic data for PD and is it functionally significant? | The top-associated SNP for ARL17A in Cortex eQTL GTEx omic data for PD is rs58879558, which has a multi-SNP SMR p-value of 2.27e-11 and a HEIDI of 0.27, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1262233', 'topRSID': 'rs58879558', 'Disease': 'PD', 'Gene': 'ARL17A', 'p_SMR_multi': 2.266335e-11, 'p_HEIDI': 0.2674944, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL GTEx', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1734 | Q67 | What is the top-associated SNP of the gene MMRN1 in Anterior Cingulate Cortex BA24 eQTL omic data for PD and is it functionally significant? | The top-associated SNP for MMRN1 in Anterior Cingulate Cortex BA24 eQTL omic data for PD is rs75943295, which has a multi-SNP SMR p-value of 5.52e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MMRN1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%anterior cingulate cortex ba24 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1486995', 'topRSID': 'rs75943295', 'Disease': 'PD', 'Gene': 'MMRN1', 'p_SMR_multi': 5.521379e-07, 'p_HEIDI': 0.002344929, 'Omic_tissue': 'Anterior Cingulate Cortex BA24', 'Omic_type': 'Anterior Cingulate Cortex BA24 eQTL', 'func_sig': 'association meets significance threshold bu... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.170 | Q67 | What is the top-associated SNP of the gene PVRIG in Caudate Basal Ganglia eQTL omic data for AD and is it functionally significant? | The top-associated SNP for PVRIG in Caudate Basal Ganglia eQTL omic data for AD is rs1628077, which has a multi-SNP SMR p-value of 2.97e-08 and a HEIDI of 0.11, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PVRIG" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1266779', 'topRSID': 'rs1628077', 'Disease': 'AD', 'Gene': 'PVRIG', 'p_SMR_multi': 2.967177e-08, 'p_HEIDI': 0.1085551, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.13 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 3.27e-23 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041740', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'MAPT', 'p_SMR_multi': 3.1929999999999995e-44, 'p_HEIDI': 3.11336e-12, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
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