uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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|---|---|---|---|---|---|---|---|---|
Q67.1927 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Brain meta-analysis mQTL omic data for PD is rs1966345, which has a multi-SNP SMR p-value of 4.68e-19 and a HEIDI of 0.1, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491139', 'topRSID': 'rs12150087', 'Disease': 'PD', 'Gene': 'KANSL1', 'p_SMR_multi': 8.107128999999999e-20, 'p_HEIDI': 0.009069932, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs o... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.174 | Q67 | What is the top-associated SNP of the gene CCS in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene CCS in Multi Ancestry Whole Brain Meta-analysis eQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CCS" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1394353', 'topRSID': 'rs519380', 'Disease': 'AD', 'Gene': 'CCS', 'p_SMR_multi': 0.6739971, 'p_HEIDI': 0.7441003, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.656 | Q67 | What is the top-associated SNP of the gene BTNL2 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for BTNL2 in Whole Blood mQTL omic data for AD is rs115303880, which has a multi-SNP SMR p-value of 2.71e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "BTNL2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_621688', 'topRSID': 'rs116522341', 'Disease': 'AD', 'Gene': 'BTNL2', 'p_SMR_multi': 2.681311e-09, 'p_HEIDI': 2.28461e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1062 | Q67 | What is the top-associated SNP of the gene MAD1L1 in Whole Blood mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene MAD1L1 in Whole Blood mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAD1L1" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_724935', 'topRSID': 'rs35622755', 'Disease': 'ALS', 'Gene': 'MAD1L1', 'p_SMR_multi': 0.1039968, 'p_HEIDI': 0.9334496, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_725006', 'top... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.263 | Q67 | What is the top-associated SNP of the gene ARL17B in Basal Ganglia eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARL17B in Basal Ganglia eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 2.06e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17B" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_27914', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'ARL17B', 'p_SMR_multi': 2.063039e-13, 'p_HEIDI': 2.583683e-12, 'Omic_tissue': 'Basal Ganglia', 'Omic_type': 'Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage D... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1427 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Tibial Nerve eQTL omic data for AD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Tibial Nerve eQTL omic data for AD is rs62062768, which has a multi-SNP SMR p-value of 1.40e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1291768', 'topRSID': 'rs62062768', 'Disease': 'AD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 1.402024e-06, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1582 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 6.22e-11 and a HEIDI of 0.14, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041740', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'MAPT', 'p_SMR_multi': 3.1929999999999995e-44, 'p_HEIDI': 3.11336e-12, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.909 | Q67 | What is the top-associated SNP of the gene PMS2P1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for PMS2P1 in Whole Blood mQTL omic data for AD is rs2405442, which has a multi-SNP SMR p-value of 2.21e-13 and a HEIDI of 0.63, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PMS2P1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_585989', 'topRSID': 'rs2405442', 'Disease': 'AD', 'Gene': 'PMS2P1', 'p_SMR_multi': 2.205734e-13, 'p_HEIDI': 0.6327656, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.679 | Q67 | What is the top-associated SNP of the gene LRRC37A in Hippocampus eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A in Hippocampus eQTL omic data for PSP is rs7225002, which has a multi-SNP SMR p-value of 4.24e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%hippocampus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_33472', 'topRSID': 'rs7225002', 'Disease': 'PSP', 'Gene': 'LRRC37A', 'p_SMR_multi': 6.312069e-11, 'p_HEIDI': 2.169444e-07, 'Omic_tissue': 'Hippocampus', 'Omic_type': 'Hippocampus eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.261 | Q67 | What is the top-associated SNP of the gene PRICKLE2 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene PRICKLE2 in Whole Brain meta-analysis mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PRICKLE2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_51200', 'topRSID': 'rs696024', 'Disease': 'AD', 'Gene': 'PRICKLE2', 'p_SMR_multi': 0.1224807, 'p_HEIDI': 0.05421155, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.851 | Q67 | What is the top-associated SNP of the gene SRPRB in Whole Blood mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene SRPRB in Whole Blood mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SRPRB" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_680351', 'topRSID': 'rs9813689', 'Disease': 'ALS', 'Gene': 'SRPRB', 'p_SMR_multi': 0.239659, 'p_HEIDI': 0.9031124, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_680354', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.874 | Q67 | What is the top-associated SNP of the gene AC005082.12 in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for AC005082.12 in Whole Blood eQTL eQTLgen omic data for PD is rs858300, which has a multi-SNP SMR p-value of 8.99e-09 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AC005082.12" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1557763', 'topRSID': 'rs858300', 'Disease': 'PD', 'Gene': 'AC005082.12', 'p_SMR_multi': 8.993726e-09, 'p_HEIDI': 0.02304777, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1564 | Q67 | What is the top-associated SNP of the gene LRRC37A4P in Whole Brain eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A4P in Whole Brain eQTL omic data for PD is rs112746008, which has a multi-SNP SMR p-value of 5.39e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A4P" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1640214', 'topRSID': 'rs112746008', 'Disease': 'PD', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 5.393237e-15, 'p_HEIDI': 0.0005447143, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.141 | Q67 | What is the top-associated SNP of the gene RN7SL32P in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for RN7SL32P in Whole Blood eQTL eQTLgen omic data for AD is rs28505715, which has a multi-SNP SMR p-value of 7.86e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RN7SL32P" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1492360', 'topRSID': 'rs28505715', 'Disease': 'AD', 'Gene': 'RN7SL32P', 'p_SMR_multi': 7.859496e-07, 'p_HEIDI': 0.0006553243, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.900 | Q67 | What is the top-associated SNP of the gene STAG3 in Frontal Cortex BA9 eQTL omic data for AD and is it functionally significant? | The top-associated SNP for STAG3 in Frontal Cortex BA9 eQTL omic data for AD is rs2950520, which has a multi-SNP SMR p-value of 2.89e-06 and a HEIDI of 0.17, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "STAG3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%frontal cortex ba9 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1156007', 'topRSID': 'rs2950520', 'Disease': 'AD', 'Gene': 'STAG3', 'p_SMR_multi': 2.892444e-06, 'p_HEIDI': 0.1697678, 'Omic_tissue': 'Frontal Cortex', 'Omic_type': 'Frontal Cortex BA9 eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1839 | Q67 | What is the top-associated SNP of the gene TTC19 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD and is it functionally significant? | The top-associated SNP for TTC19 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD is rs11078331, which has a multi-SNP SMR p-value of 2.07e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TTC19" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1435717', 'topRSID': 'rs11078331', 'Disease': 'PD', 'Gene': 'TTC19', 'p_SMR_multi': 2.065432e-06, 'p_HEIDI': 6.367344e-05, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thres... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.555 | Q67 | What is the top-associated SNP of the gene CHRNE in Tibial Nerve eQTL omic data for AD and is it functionally significant? | The top-associated SNP for CHRNE in Tibial Nerve eQTL omic data for AD is rs72835059, which has a multi-SNP SMR p-value of 2.26e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CHRNE" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1291498', 'topRSID': 'rs72835059', 'Disease': 'AD', 'Gene': 'CHRNE', 'p_SMR_multi': 2.261932e-06, 'p_HEIDI': 0.003486666, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.323 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Blood mQTL omic data for PD is rs34465449, which has a multi-SNP SMR p-value of 1.55e-08 and a HEIDI of 0.03, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948846', 'topRSID': 'rs35489312', 'Disease': 'PD', 'Gene': 'ARHGAP27', 'p_SMR_multi': 3.386602e-15, 'p_HEIDI': 0.001263654, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1854 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Tibial Nerve eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A2 in Tibial Nerve eQTL omic data for PSP is rs12373139, which has a multi-SNP SMR p-value of 8.61e-30 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1336298', 'topRSID': 'rs12373139', 'Disease': 'PSP', 'Gene': 'LRRC37A2', 'p_SMR_multi': 8.612767e-30, 'p_HEIDI': 6.468901e-15, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1235 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Blood mQTL omic data for PSP is rs17692129, which has a multi-SNP SMR p-value of 7.93e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041761', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'KANSL1', 'p_SMR_multi': 3.489683e-40, 'p_HEIDI': 3.497522e-13, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1726 | Q67 | What is the top-associated SNP of the gene ZNF232 in Cortex eQTL metaBrain omic data for AD and is it functionally significant? | The top-associated SNP for ZNF232 in Cortex eQTL metaBrain omic data for AD is rs143649705, which has a multi-SNP SMR p-value of 1.93e-06 and a HEIDI of 0.15, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZNF232" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1106586', 'topRSID': 'rs143649705', 'Disease': 'AD', 'Gene': 'ZNF232', 'p_SMR_multi': 1.932692e-06, 'p_HEIDI': 0.1532913, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.564 | Q67 | What is the top-associated SNP of the gene C9orf72 in Cerebellum eQTL omic data for ALS and is it functionally significant? | The top-associated SNP for C9orf72 in Cerebellum eQTL omic data for ALS is rs774358, which has a multi-SNP SMR p-value of 1.42e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C9orf72" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_4374', 'topRSID': 'rs13691', 'Disease': 'ALS', 'Gene': 'C9orf72', 'p_SMR_multi': 5.567312e-12, 'p_HEIDI': 0.0001376868, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequil... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.142 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PD is rs113575082, which has a multi-SNP SMR p-value of 8.05e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491057', 'topRSID': 'rs62065376', 'Disease': 'PD', 'Gene': 'ARHGAP27', 'p_SMR_multi': 1.134698e-11, 'p_HEIDI': 0.3072466, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1736 | Q67 | What is the top-associated SNP of the gene CD2AP in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for CD2AP in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs12200115, which has a multi-SNP SMR p-value of 6.09e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CD2AP" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1392018', 'topRSID': 'rs12200115', 'Disease': 'AD', 'Gene': 'CD2AP', 'p_SMR_multi': 6.092703e-07, 'p_HEIDI': 3.494603e-08, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thres... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.537 | Q67 | What is the top-associated SNP of the gene WNT3 in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for WNT3 in Whole Blood mQTL omic data for PSP is rs8074816, which has a multi-SNP SMR p-value of 2.63e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "WNT3" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041775', 'topRSID': 'rs8074816', 'Disease': 'PSP', 'Gene': 'WNT3', 'p_SMR_multi': 2.627101e-06, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequili... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.227 | Q67 | What is the top-associated SNP of the gene AC007879.5 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene AC007879.5 in Whole Brain meta-analysis mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AC007879.5" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_47669', 'topRSID': 'rs60267371', 'Disease': 'AD', 'Gene': 'AC007879.5', 'p_SMR_multi': 0.07754257, 'p_HEIDI': 0.413305, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_te... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.730 | Q67 | What is the top-associated SNP of the gene CRHR1-IT1 in Anterior Cingulate Cortex BA24 eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for CRHR1-IT1 in Anterior Cingulate Cortex BA24 eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 7.92e-16 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1-IT1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%anterior cingulate cortex ba24 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1489536', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'CRHR1-IT1', 'p_SMR_multi': 7.915804e-16, 'p_HEIDI': 7.923941e-18, 'Omic_tissue': 'Anterior Cingulate Cortex BA24', 'Omic_type': 'Anterior Cingulate Cortex BA24 eQTL', 'func_sig': 'association meets significance thresho... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.793 | Q67 | What is the top-associated SNP of the gene ACMSD in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for ACMSD in Whole Blood mQTL omic data for PD is rs4953936, which has a multi-SNP SMR p-value of 2.78e-06 and a HEIDI of 0.1, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ACMSD" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1019156', 'topRSID': 'rs4953936', 'Disease': 'PD', 'Gene': 'ACMSD', 'p_SMR_multi': 2.77516e-06, 'p_HEIDI': 0.09989063, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1019157', 'topRS... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1718 | Q67 | What is the top-associated SNP of the gene RP11-259G18.2 in Whole Blood eQTL eQTLgen omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.2 in Whole Blood eQTL eQTLgen omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 2.48e-35 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1579423', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'RP11-259G18.2', 'p_SMR_multi': 2.477035e-35, 'p_HEIDI': 7.022902e-07, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.994 | Q67 | What is the top-associated SNP of the gene ZNF668 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD and is it functionally significant? | The top-associated SNP for ZNF668 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD is rs4889530, which has a multi-SNP SMR p-value of 1.47e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZNF668" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1435345', 'topRSID': 'rs4889530', 'Disease': 'PD', 'Gene': 'ZNF668', 'p_SMR_multi': 1.474019e-07, 'p_HEIDI': 2.338424e-09, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thres... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.415 | Q67 | What is the top-associated SNP of the gene RP11-385F7.1 in Cerebellum eQTL omic data for AD and is it functionally significant? | The top-associated SNP for RP11-385F7.1 in Cerebellum eQTL omic data for AD is rs9381564, which has a multi-SNP SMR p-value of 9.62e-08 and a HEIDI of 0.4, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-385F7.1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1687622', 'topRSID': 'rs9381564', 'Disease': 'AD', 'Gene': 'RP11-385F7.1', 'p_SMR_multi': 9.617745e-08, 'p_HEIDI': 0.3965234, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.329 | Q67 | What is the top-associated SNP of the gene IDUA in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for IDUA in Whole Blood mQTL omic data for PD is rs10010999, which has a multi-SNP SMR p-value of 1.21e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IDUA" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996313', 'topRSID': 'rs11936407', 'Disease': 'PD', 'Gene': 'IDUA', 'p_SMR_multi': 1.158943e-09, 'p_HEIDI': 4.775076e-12, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1098 | Q67 | What is the top-associated SNP of the gene RP11-282O18.3 in Cerebellum eQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene RP11-282O18.3 in Cerebellum eQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-282O18.3" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1699352', 'topRSID': 'rs940904', 'Disease': 'FTD', 'Gene': 'RP11-282O18.3', 'p_SMR_multi': 0.6174553, 'p_HEIDI': 0.6758589, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.303 | Q67 | What is the top-associated SNP of the gene NDUFAF6 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for NDUFAF6 in Whole Blood mQTL omic data for AD is rs896853, which has a multi-SNP SMR p-value of 2.77e-06 and a HEIDI of 0.18, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NDUFAF6" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_616798', 'topRSID': 'rs1320164', 'Disease': 'AD', 'Gene': 'NDUFAF6', 'p_SMR_multi': 1.716817e-06, 'p_HEIDI': 0.2600196, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_616796', 'topRS... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1259 | Q67 | What is the top-associated SNP of the gene AC053503.4 in Whole Blood mQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene AC053503.4 in Whole Blood mQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AC053503.4" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1075625', 'topRSID': 'rs6436150', 'Disease': 'PSP', 'Gene': 'AC053503.4', 'p_SMR_multi': 0.02070025, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1996 | Q67 | What is the top-associated SNP of the gene GSTA1 in Cortex eQTL GTEx omic data for LBD and is it functionally significant? | There are no SNPs within the gene GSTA1 in Cortex eQTL GTEx omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GSTA1" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%cortex eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1256640', 'topRSID': 'rs60120296', 'Disease': 'LBD', 'Gene': 'GSTA1', 'p_SMR_multi': 0.7480404, 'p_HEIDI': 0.3776068, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL GTEx', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.26 | Q67 | What is the top-associated SNP of the gene PLEKHM1 in Whole Brain eQTL omic data for PD and is it functionally significant? | The top-associated SNP for PLEKHM1 in Whole Brain eQTL omic data for PD is rs113434679, which has a multi-SNP SMR p-value of 7.17e-07 and a HEIDI of 0.31, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PLEKHM1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1640212', 'topRSID': 'rs113434679', 'Disease': 'PD', 'Gene': 'PLEKHM1', 'p_SMR_multi': 7.172429e-07, 'p_HEIDI': 0.3130195, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1860 | Q67 | What is the top-associated SNP of the gene NFYA in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for NFYA in Whole Blood mQTL omic data for AD is rs62396353, which has a multi-SNP SMR p-value of 7.80e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NFYA" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_622639', 'topRSID': 'rs72856298', 'Disease': 'AD', 'Gene': 'NFYA', 'p_SMR_multi': 3.336665e-10, 'p_HEIDI': 1.123977e-10, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.721 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Brain meta-analysis mQTL omic data for AD is rs10514904, which has a multi-SNP SMR p-value of 7.69e-07 and a HEIDI of 0.03, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_115207', 'topRSID': 'rs2696569', 'Disease': 'AD', 'Gene': 'KANSL1', 'p_SMR_multi': 5.266316e-08, 'p_HEIDI': 0.01258408, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.996 | Q67 | What is the top-associated SNP of the gene TMEM175 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for TMEM175 in Whole Blood mQTL omic data for PD is rs11724898, which has a multi-SNP SMR p-value of 1.05e-06 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TMEM175" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996283', 'topRSID': 'rs6813110', 'Disease': 'PD', 'Gene': 'TMEM175', 'p_SMR_multi': 2.618289e-11, 'p_HEIDI': 0.0001221027, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.196 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Whole Brain eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Whole Brain eQTL omic data for PD is rs1378358, which has a multi-SNP SMR p-value of 6.39e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1640222', 'topRSID': 'rs1378358', 'Disease': 'PD', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 6.392017e-15, 'p_HEIDI': 3.459837e-09, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.446 | Q67 | What is the top-associated SNP of the gene TMEM175 in Cerebellar Hemisphere eQTL omic data for PD and is it functionally significant? | The top-associated SNP for TMEM175 in Cerebellar Hemisphere eQTL omic data for PD is rs4690203, which has a multi-SNP SMR p-value of 2.33e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TMEM175" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1188708', 'topRSID': 'rs4690203', 'Disease': 'PD', 'Gene': 'TMEM175', 'p_SMR_multi': 2.332517e-06, 'p_HEIDI': 0.007003691, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'association meets significance threshold but shows signs of ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.579 | Q67 | What is the top-associated SNP of the gene ARL17A in Cerebellum eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARL17A in Cerebellum eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 3.38e-20 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_22221', 'topRSID': 'rs393152', 'Disease': 'PSP', 'Gene': 'ARL17A', 'p_SMR_multi': 7.062669e-30, 'p_HEIDI': 1.359857e-15, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequi... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.955 | Q67 | What is the top-associated SNP of the gene IDUA in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for IDUA in Whole Brain meta-analysis mQTL omic data for PD is rs11248061, which has a multi-SNP SMR p-value of 1.16e-08 and a HEIDI of 0.14, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IDUA" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_429873', 'topRSID': 'rs1051613', 'Disease': 'PD', 'Gene': 'IDUA', 'p_SMR_multi': 4.554749e-13, 'p_HEIDI': 2.213052e-05, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.509 | Q67 | What is the top-associated SNP of the gene PSORS1C1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for PSORS1C1 in Whole Blood mQTL omic data for AD is rs707913, which has a multi-SNP SMR p-value of 1.50e-06 and a HEIDI of 0.26, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PSORS1C1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_620729', 'topRSID': 'rs9501055', 'Disease': 'AD', 'Gene': 'PSORS1C1', 'p_SMR_multi': 5.485384e-08, 'p_HEIDI': 0.004858996, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.612 | Q67 | What is the top-associated SNP of the gene GALT in Caudate Basal Ganglia eQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene GALT in Caudate Basal Ganglia eQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GALT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1280230', 'topRSID': 'rs2070074', 'Disease': 'PD', 'Gene': 'GALT', 'p_SMR_multi': 0.7247125, 'p_HEIDI': 0.6595399, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1864 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 4.71e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560864', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'MAPT', 'p_SMR_multi': 2.100115e-44, 'p_HEIDI': 0.01425494, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_56... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1725 | Q67 | What is the top-associated SNP of the gene PVRIG in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for PVRIG in Whole Blood eQTL eQTLgen omic data for AD is rs2005763, which has a multi-SNP SMR p-value of 2.87e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PVRIG" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1495801', 'topRSID': 'rs2005763', 'Disease': 'AD', 'Gene': 'PVRIG', 'p_SMR_multi': 2.872066e-13, 'p_HEIDI': 1.018913e-09, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1885 | Q67 | What is the top-associated SNP of the gene TNIP1 in Whole Blood eQTL eQTLgen omic data for ALS and is it functionally significant? | The top-associated SNP for TNIP1 in Whole Blood eQTL eQTLgen omic data for ALS is rs12518386, which has a multi-SNP SMR p-value of 5.53e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TNIP1" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1509997', 'topRSID': 'rs12518386', 'Disease': 'ALS', 'Gene': 'TNIP1', 'p_SMR_multi': 5.531637e-10, 'p_HEIDI': 0.0006579186, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.853 | Q67 | What is the top-associated SNP of the gene KANSL1 in Caudate Basal Ganglia eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1 in Caudate Basal Ganglia eQTL omic data for PSP is rs17692129, which has a multi-SNP SMR p-value of 1.46e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1283702', 'topRSID': 'rs17692129', 'Disease': 'PSP', 'Gene': 'KANSL1', 'p_SMR_multi': 1.458009e-09, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs of lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.4 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Nucleus Accumbens Basal Ganglia omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Nucleus Accumbens Basal Ganglia omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 1.08e-12 and a HEIDI of 0.07, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1730065', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 1.078886e-12, 'p_HEIDI': 0.07235706, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1569 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PD is rs56220387, which has a multi-SNP SMR p-value of 2.04e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491057', 'topRSID': 'rs62065376', 'Disease': 'PD', 'Gene': 'ARHGAP27', 'p_SMR_multi': 1.134698e-11, 'p_HEIDI': 0.3072466, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1461 | Q67 | What is the top-associated SNP of the gene AC012146.7 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for AC012146.7 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs73976311, which has a multi-SNP SMR p-value of 1.69e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AC012146.7" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT... | [{'UUID': 'NDD_SMR_genes_all_update_text_1396457', 'topRSID': 'rs73976311', 'Disease': 'AD', 'Gene': 'AC012146.7', 'p_SMR_multi': 1.693054e-07, 'p_HEIDI': 5.131379e-06, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.473 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Blood mQTL omic data for PSP is rs17692129, which has a multi-SNP SMR p-value of 1.19e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041761', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'KANSL1', 'p_SMR_multi': 3.489683e-40, 'p_HEIDI': 3.497522e-13, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.325 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Nucleus Accumbens Basal Ganglia omic data for AD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Nucleus Accumbens Basal Ganglia omic data for AD is rs413917, which has a multi-SNP SMR p-value of 6.97e-07 and a HEIDI of 0.48, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1717385', 'topRSID': 'rs413917', 'Disease': 'AD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 6.966281e-07, 'p_HEIDI': 0.484854, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.6 | Q67 | What is the top-associated SNP of the gene STX4 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for STX4 in Whole Blood mQTL omic data for PD is rs4889609, which has a multi-SNP SMR p-value of 4.22e-07 and a HEIDI of 0.12, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "STX4" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_974678', 'topRSID': 'rs4889609', 'Disease': 'PD', 'Gene': 'STX4', 'p_SMR_multi': 4.215464e-07, 'p_HEIDI': 0.1161469, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_974676', 'topRSID'... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.225 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Blood mQTL omic data for PD is rs2532233, which has a multi-SNP SMR p-value of 2.34e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948907', 'topRSID': 'rs2532233', 'Disease': 'PD', 'Gene': 'KANSL1', 'p_SMR_multi': 1.024112e-14, 'p_HEIDI': 2.989456e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1376 | Q67 | What is the top-associated SNP of the gene TMEM236 in Skeletal Muscle eQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene TMEM236 in Skeletal Muscle eQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TMEM236" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1347962', 'topRSID': 'rs2688796', 'Disease': 'ALS', 'Gene': 'TMEM236', 'p_SMR_multi': 0.6795279, 'p_HEIDI': 0.4335514, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.553 | Q67 | What is the top-associated SNP of the gene CD55 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CD55 in Whole Blood mQTL omic data for AD is rs7545125, which has a multi-SNP SMR p-value of 7.09e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CD55" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_655837', 'topRSID': 'rs7545125', 'Disease': 'AD', 'Gene': 'CD55', 'p_SMR_multi': 7.09095e-09, 'p_HEIDI': 2.39175e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequil... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.231 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Whole Blood eQTL eQTLgen omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Whole Blood eQTL eQTLgen omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 7.66e-48 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1579422', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 7.658957999999999e-48, 'p_HEIDI': 8.544617e-10, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.40 | Q67 | What is the top-associated SNP of the gene DOCK9-AS2 in Nucleus Accumbens Basal Ganglia omic data for PD and is it functionally significant? | There are no SNPs within the gene DOCK9-AS2 in Nucleus Accumbens Basal Ganglia omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DOCK9-AS2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1729572', 'topRSID': 'rs9557137', 'Disease': 'PD', 'Gene': 'DOCK9-AS2', 'p_SMR_multi': 0.07397846, 'p_HEIDI': 0.5315329, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.548 | Q67 | What is the top-associated SNP of the gene UBE2K in Tibial Nerve eQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene UBE2K in Tibial Nerve eQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "UBE2K" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1295677', 'topRSID': 'rs305132', 'Disease': 'ALS', 'Gene': 'UBE2K', 'p_SMR_multi': 0.6804347, 'p_HEIDI': 0.5185377, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.245 | Q67 | What is the top-associated SNP of the gene ARL17B in Spinalcord eQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARL17B in Spinalcord eQTL omic data for PD is rs199451, which has a multi-SNP SMR p-value of 6.42e-09 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%spinalcord eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_30030', 'topRSID': 'rs199451', 'Disease': 'PD', 'Gene': 'ARL17B', 'p_SMR_multi': 6.417524e-09, 'p_HEIDI': 0.01223556, 'Omic_tissue': 'Spinalcord', 'Omic_type': 'Spinalcord eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.905 | Q67 | What is the top-associated SNP of the gene TAF6 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for TAF6 in Whole Blood eQTL eQTLgen omic data for AD is rs6960432, which has a multi-SNP SMR p-value of 5.24e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TAF6" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1495793', 'topRSID': 'rs6960432', 'Disease': 'AD', 'Gene': 'TAF6', 'p_SMR_multi': 5.244342e-08, 'p_HEIDI': 4.246328e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1429 | Q67 | What is the top-associated SNP of the gene ZNF197 in Skeletal Muscle eQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene ZNF197 in Skeletal Muscle eQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZNF197" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1359360', 'topRSID': 'rs9868960', 'Disease': 'LBD', 'Gene': 'ZNF197', 'p_SMR_multi': 0.8795243, 'p_HEIDI': 0.8844666, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.139 | Q67 | What is the top-associated SNP of the gene APH1B in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for APH1B in Whole Blood eQTL eQTLgen omic data for AD is rs75763893, which has a multi-SNP SMR p-value of 9.50e-09 and a HEIDI of 0.07, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APH1B" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1500804', 'topRSID': 'rs75763893', 'Disease': 'AD', 'Gene': 'APH1B', 'p_SMR_multi': 9.497064e-09, 'p_HEIDI': 0.06957858, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1191 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Blood mQTL omic data for PD is rs11012, which has a multi-SNP SMR p-value of 1.41e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948846', 'topRSID': 'rs35489312', 'Disease': 'PD', 'Gene': 'ARHGAP27', 'p_SMR_multi': 3.386602e-15, 'p_HEIDI': 0.001263654, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1757 | Q67 | What is the top-associated SNP of the gene IGSF9B in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for IGSF9B in Whole Brain meta-analysis mQTL omic data for PD is rs167915, which has a multi-SNP SMR p-value of 5.59e-09 and a HEIDI of 0.12, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IGSF9B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_470339', 'topRSID': 'rs1793680', 'Disease': 'PD', 'Gene': 'IGSF9B', 'p_SMR_multi': 2.071103e-10, 'p_HEIDI': 0.006061729, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1573 | Q67 | What is the top-associated SNP of the gene APOC2 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for APOC2 in Whole Blood mQTL omic data for AD is rs5120, which has a multi-SNP SMR p-value of 1.28e-24 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APOC2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_637437', 'topRSID': 'rs5120', 'Disease': 'AD', 'Gene': 'APOC2', 'p_SMR_multi': 1.276397e-24, 'p_HEIDI': 2.572368e-19, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequil... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1443 | Q67 | What is the top-associated SNP of the gene LRRC37A in Hypothalamus eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A in Hypothalamus eQTL omic data for PD is rs3874943, which has a multi-SNP SMR p-value of 1.24e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%hypothalamus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1462900', 'topRSID': 'rs3874943', 'Disease': 'PD', 'Gene': 'LRRC37A', 'p_SMR_multi': 1.237554e-08, 'p_HEIDI': 5.199905e-05, 'Omic_tissue': 'Hypothalamus', 'Omic_type': 'Hypothalamus eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.836 | Q67 | What is the top-associated SNP of the gene GPC2 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for GPC2 in Whole Brain meta-analysis mQTL omic data for AD is rs866500, which has a multi-SNP SMR p-value of 6.78e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GPC2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_74045', 'topRSID': 'rs866500', 'Disease': 'AD', 'Gene': 'GPC2', 'p_SMR_multi': 6.77721e-09, 'p_HEIDI': 5.570468e-05, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.451 | Q67 | What is the top-associated SNP of the gene SPPL2C in Cerebellum eQTL omic data for AD and is it functionally significant? | The top-associated SNP for SPPL2C in Cerebellum eQTL omic data for AD is rs17573607, which has a multi-SNP SMR p-value of 2.71e-06 and a HEIDI of 0.92, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SPPL2C" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_2656', 'topRSID': 'rs2532233', 'Disease': 'AD', 'Gene': 'SPPL2C', 'p_SMR_multi': 2.367296e-06, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequilibriu... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.849 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Blood mQTL omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 1.91e-08 and a HEIDI of 0.21, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041709', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'ARHGAP27', 'p_SMR_multi': 3.175631e-40, 'p_HEIDI': 2.761191e-07, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1087 | Q67 | What is the top-associated SNP of the gene COL4A2 in Whole Blood mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene COL4A2 in Whole Blood mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "COL4A2" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_664489', 'topRSID': 'rs9583484', 'Disease': 'ALS', 'Gene': 'COL4A2', 'p_SMR_multi': 0.142685, 'p_HEIDI': 0.6088831, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_664509', 'topRS... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1420 | Q67 | What is the top-associated SNP of the gene MGC10955 in Liver eQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene MGC10955 in Liver eQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MGC10955" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%liver eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1474718', 'topRSID': 'rs4852329', 'Disease': 'PD', 'Gene': 'MGC10955', 'p_SMR_multi': 0.5763493, 'p_HEIDI': 0.02181291, 'Omic_tissue': 'Liver', 'Omic_type': 'Liver eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1154 | Q67 | What is the top-associated SNP of the gene MS4A3 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for MS4A3 in Whole Blood mQTL omic data for AD is rs1286162, which has a multi-SNP SMR p-value of 5.04e-17 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MS4A3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_608692', 'topRSID': 'rs1286162', 'Disease': 'AD', 'Gene': 'MS4A3', 'p_SMR_multi': 5.0399240000000004e-17, 'p_HEIDI': 4.552088e-10, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1826 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PD is rs2532233, which has a multi-SNP SMR p-value of 7.25e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948891', 'topRSID': 'rs62063271', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 6.382411e-15, 'p_HEIDI': 2.368028e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.588 | Q67 | What is the top-associated SNP of the gene APOC2 in Putamen Basal Ganglia eQTL omic data for AD and is it functionally significant? | The top-associated SNP for APOC2 in Putamen Basal Ganglia eQTL omic data for AD is rs11878597, which has a multi-SNP SMR p-value of 1.65e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APOC2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1584547', 'topRSID': 'rs11878597', 'Disease': 'AD', 'Gene': 'APOC2', 'p_SMR_multi': 1.648401e-10, 'p_HEIDI': 0.0001479393, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs of ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1892 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Blood mQTL omic data for PD is rs35489312, which has a multi-SNP SMR p-value of 3.39e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948846', 'topRSID': 'rs35489312', 'Disease': 'PD', 'Gene': 'ARHGAP27', 'p_SMR_multi': 3.386602e-15, 'p_HEIDI': 0.001263654, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1970 | Q67 | What is the top-associated SNP of the gene ZKSCAN1 in Tibial Nerve eQTL omic data for AD and is it functionally significant? | The top-associated SNP for ZKSCAN1 in Tibial Nerve eQTL omic data for AD is rs4216, which has a multi-SNP SMR p-value of 6.58e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZKSCAN1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1287862', 'topRSID': 'rs4216', 'Disease': 'AD', 'Gene': 'ZKSCAN1', 'p_SMR_multi': 6.579727e-08, 'p_HEIDI': 0.005668404, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.668 | Q67 | What is the top-associated SNP of the gene LRRC37A in Whole Blood eQTL GTEx omic data for AD and is it functionally significant? | The top-associated SNP for LRRC37A in Whole Blood eQTL GTEx omic data for AD is rs4510068, which has a multi-SNP SMR p-value of 1.61e-06 and a HEIDI of 0.08, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1652503', 'topRSID': 'rs4510068', 'Disease': 'AD', 'Gene': 'LRRC37A', 'p_SMR_multi': 1.613978e-06, 'p_HEIDI': 0.08107542, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.442 | Q67 | What is the top-associated SNP of the gene PPP4C in Whole Brain eQTL omic data for AD and is it functionally significant? | The top-associated SNP for PPP4C in Whole Brain eQTL omic data for AD is rs12596543, which has a multi-SNP SMR p-value of 9.70e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PPP4C" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1610395', 'topRSID': 'rs12596543', 'Disease': 'AD', 'Gene': 'PPP4C', 'p_SMR_multi': 9.704975e-07, 'p_HEIDI': 0.001155741, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1857 | Q67 | What is the top-associated SNP of the gene RP11-798G7.8 in Skeletal Muscle eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-798G7.8 in Skeletal Muscle eQTL omic data for PSP is rs12373139, which has a multi-SNP SMR p-value of 1.35e-17 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-798G7.8" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1375924', 'topRSID': 'rs12373139', 'Disease': 'PSP', 'Gene': 'RP11-798G7.8', 'p_SMR_multi': 1.3497710000000001e-17, 'p_HEIDI': 5.003598e-08, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows sig... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.382 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Blood mQTL omic data for PSP is rs415430, which has a multi-SNP SMR p-value of 1.09e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041761', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'KANSL1', 'p_SMR_multi': 3.489683e-40, 'p_HEIDI': 3.497522e-13, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1478 | Q67 | What is the top-associated SNP of the gene EPHA1 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for EPHA1 in Whole Brain meta-analysis mQTL omic data for AD is rs3935067, which has a multi-SNP SMR p-value of 1.96e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "EPHA1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_75159', 'topRSID': 'rs3935067', 'Disease': 'AD', 'Gene': 'EPHA1', 'p_SMR_multi': 1.964008e-09, 'p_HEIDI': 0.004901496, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ L... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.974 | Q67 | What is the top-associated SNP of the gene GEMIN7 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for GEMIN7 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs3178166, which has a multi-SNP SMR p-value of 6.61e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GEMIN7" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1397650', 'topRSID': 'rs3178166', 'Disease': 'AD', 'Gene': 'GEMIN7', 'p_SMR_multi': 6.611665e-08, 'p_HEIDI': 8.975728e-08, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thres... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1210 | Q67 | What is the top-associated SNP of the gene SNX31 in Skeletal Muscle eQTL omic data for AD and is it functionally significant? | The top-associated SNP for SNX31 in Skeletal Muscle eQTL omic data for AD is rs1693551, which has a multi-SNP SMR p-value of 2.01e-07 and a HEIDI of 0.59, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SNX31" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1340611', 'topRSID': 'rs1693551', 'Disease': 'AD', 'Gene': 'SNX31', 'p_SMR_multi': 2.012102e-07, 'p_HEIDI': 0.5921966, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.318 | Q67 | What is the top-associated SNP of the gene FAM200B in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD and is it functionally significant? | The top-associated SNP for FAM200B in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD is rs6815254, which has a multi-SNP SMR p-value of 1.16e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FAM200B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 10... | [{'UUID': 'NDD_SMR_genes_all_update_text_1430254', 'topRSID': 'rs6815254', 'Disease': 'PD', 'Gene': 'FAM200B', 'p_SMR_multi': 1.160805e-06, 'p_HEIDI': 1.225634e-06, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thre... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.698 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Tibial Nerve eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Tibial Nerve eQTL omic data for PD is rs199456, which has a multi-SNP SMR p-value of 9.21e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1328934', 'topRSID': 'rs199456', 'Disease': 'PD', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 9.205373e-14, 'p_HEIDI': 0.003589979, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1505 | Q67 | What is the top-associated SNP of the gene SHROOM3 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for SHROOM3 in Whole Blood mQTL omic data for PD is rs59136511, which has a multi-SNP SMR p-value of 5.14e-07 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SHROOM3" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_998381', 'topRSID': 'rs59136511', 'Disease': 'PD', 'Gene': 'SHROOM3', 'p_SMR_multi': 5.144308e-07, 'p_HEIDI': 0.02260865, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_998379', 'top... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.430 | Q67 | What is the top-associated SNP of the gene RP11-259G18.2 in Frontal Cortex BA9 eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.2 in Frontal Cortex BA9 eQTL omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 5.84e-11 and a HEIDI of 0.33, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%frontal cortex ba9 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1168836', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'RP11-259G18.2', 'p_SMR_multi': 5.837979e-11, 'p_HEIDI': 0.3294297, 'Omic_tissue': 'Frontal Cortex', 'Omic_type': 'Frontal Cortex BA9 eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.601 | Q67 | What is the top-associated SNP of the gene CLASRP in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CLASRP in Whole Blood mQTL omic data for AD is rs1560725, which has a multi-SNP SMR p-value of 2.09e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CLASRP" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_637443', 'topRSID': 'rs1560725', 'Disease': 'AD', 'Gene': 'CLASRP', 'p_SMR_multi': 2.085517e-14, 'p_HEIDI': 7.727262e-12, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1964 | Q67 | What is the top-associated SNP of the gene GIMAP8 in Prefrontal Cortex eQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene GIMAP8 in Prefrontal Cortex eQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GIMAP8" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1199037', 'topRSID': 'rs6464067', 'Disease': 'AD', 'Gene': 'GIMAP8', 'p_SMR_multi': 0.1685823, 'p_HEIDI': 0.07730442, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.629 | Q67 | What is the top-associated SNP of the gene LRRC37A4P in Caudate Basal Ganglia eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A4P in Caudate Basal Ganglia eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 1.41e-20 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A4P" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1283697', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 1.414601e-20, 'p_HEIDI': 2.471783e-24, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1170 | Q67 | What is the top-associated SNP of the gene GRN in Tibial Nerve eQTL omic data for AD and is it functionally significant? | The top-associated SNP for GRN in Tibial Nerve eQTL omic data for AD is rs5848, which has a multi-SNP SMR p-value of 1.09e-06 and a HEIDI of 0.06, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GRN" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1291740', 'topRSID': 'rs5848', 'Disease': 'AD', 'Gene': 'GRN', 'p_SMR_multi': 1.094655e-06, 'p_HEIDI': 0.06459453, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1254 | Q67 | What is the top-associated SNP of the gene REEP1 in Cortex eQTL metaBrain omic data for FTD and is it functionally significant? | There are no SNPs within the gene REEP1 in Cortex eQTL metaBrain omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "REEP1" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1122035', 'topRSID': 'rs10165626', 'Disease': 'FTD', 'Gene': 'REEP1', 'p_SMR_multi': 0.8591722, 'p_HEIDI': 0.6790672, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.230 | Q67 | What is the top-associated SNP of the gene SH2D4B in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for SH2D4B in Whole Blood mQTL omic data for AD is rs34533074, which has a multi-SNP SMR p-value of 4.23e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SH2D4B" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_572665', 'topRSID': 'rs11186258', 'Disease': 'AD', 'Gene': 'SH2D4B', 'p_SMR_multi': 2.621326e-08, 'p_HEIDI': 0.001258736, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1180 | Q67 | What is the top-associated SNP of the gene CASP8 in Whole Blood mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene CASP8 in Whole Blood mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CASP8" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_708613', 'topRSID': 'rs12620010', 'Disease': 'ALS', 'Gene': 'CASP8', 'p_SMR_multi': 0.06219831, 'p_HEIDI': 0.2474889, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_708614', 'top... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1332 | Q67 | What is the top-associated SNP of the gene RP11-156P1.3 in Whole Blood eQTL eQTLgen omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-156P1.3 in Whole Blood eQTL eQTLgen omic data for PSP is rs10491149, which has a multi-SNP SMR p-value of 8.77e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-156P1.3" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1579436', 'topRSID': 'rs10491149', 'Disease': 'PSP', 'Gene': 'RP11-156P1.3', 'p_SMR_multi': 8.772626e-08, 'p_HEIDI': 0.007865466, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1587 | Q67 | What is the top-associated SNP of the gene ARL17A in Basal Ganglia eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARL17A in Basal Ganglia eQTL omic data for PSP is rs393152, which has a multi-SNP SMR p-value of 4.74e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1283711', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'ARL17A', 'p_SMR_multi': 4.692457e-14, 'p_HEIDI': 9.982045e-08, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs of... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
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