uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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|---|---|---|---|---|---|---|---|---|
Q67.69 | Q67 | What is the top-associated SNP of the gene POU5F1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for POU5F1 in Whole Blood mQTL omic data for AD is rs1265098, which has a multi-SNP SMR p-value of 1.17e-06 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "POU5F1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_620801', 'topRSID': 'rs1265098', 'Disease': 'AD', 'Gene': 'POU5F1', 'p_SMR_multi': 1.168562e-06, 'p_HEIDI': 0.01435111, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_620795', 'topRS... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.25 | Q67 | What is the top-associated SNP of the gene FAM115D in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for FAM115D in Whole Blood eQTL eQTLgen omic data for AD is rs2949770, which has a multi-SNP SMR p-value of 1.24e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FAM115D" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1496074', 'topRSID': 'rs2949770', 'Disease': 'AD', 'Gene': 'FAM115D', 'p_SMR_multi': 1.235843e-06, 'p_HEIDI': 0.0009931984, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.147 | Q67 | What is the top-associated SNP of the gene ARL17A in Whole Blood eQTL GTEx omic data for PD and is it functionally significant? | The top-associated SNP for ARL17A in Whole Blood eQTL GTEx omic data for PD is rs62074125, which has a multi-SNP SMR p-value of 1.59e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1679573', 'topRSID': 'rs62074125', 'Disease': 'PD', 'Gene': 'ARL17A', 'p_SMR_multi': 1.590794e-06, 'p_HEIDI': 1.19096e-09, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.542 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 5.24e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560834', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'ARHGAP27', 'p_SMR_multi': 9.282341e-28, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.818 | Q67 | What is the top-associated SNP of the gene SLC4A11 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene SLC4A11 in Whole Brain meta-analysis mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SLC4A11" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_500193', 'topRSID': 'rs1207', 'Disease': 'PD', 'Gene': 'SLC4A11', 'p_SMR_multi': 0.006190685, 'p_HEIDI': 0.04623798, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1120 | Q67 | What is the top-associated SNP of the gene C6orf10 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for C6orf10 in Whole Blood mQTL omic data for AD is rs35265698, which has a multi-SNP SMR p-value of 2.93e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C6orf10" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_621662', 'topRSID': 'rs35265698', 'Disease': 'AD', 'Gene': 'C6orf10', 'p_SMR_multi': 2.929935e-08, 'p_HEIDI': 2.344082e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.88 | Q67 | What is the top-associated SNP of the gene NDUFS2 in Cortex eQTL metaBrain omic data for AD and is it functionally significant? | The top-associated SNP for NDUFS2 in Cortex eQTL metaBrain omic data for AD is rs33941127, which has a multi-SNP SMR p-value of 6.50e-07 and a HEIDI of 0.22, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NDUFS2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1105079', 'topRSID': 'rs33941127', 'Disease': 'AD', 'Gene': 'NDUFS2', 'p_SMR_multi': 6.50274e-07, 'p_HEIDI': 0.2233147, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1183 | Q67 | What is the top-associated SNP of the gene ARL17B in Cortex eQTL metaBrain omic data for PSP and is it functionally significant? | The top-associated SNP for ARL17B in Cortex eQTL metaBrain omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 4.47e-42 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17B" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1154399', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'ARL17B', 'p_SMR_multi': 4.4691469999999997e-42, 'p_HEIDI': 3.22368e-33, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1333 | Q67 | What is the top-associated SNP of the gene MCCC1 in Whole Brain meta-analysis mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene MCCC1 in Whole Brain meta-analysis mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MCCC1" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_244107', 'topRSID': 'rs1995426', 'Disease': 'FTD', 'Gene': 'MCCC1', 'p_SMR_multi': 0.04549747, 'p_HEIDI': 0.3134733, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1806 | Q67 | What is the top-associated SNP of the gene INO80E in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for INO80E in Whole Brain meta-analysis mQTL omic data for AD is rs12928610, which has a multi-SNP SMR p-value of 1.65e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "INO80E" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_109450', 'topRSID': 'rs10871451', 'Disease': 'AD', 'Gene': 'INO80E', 'p_SMR_multi': 2.528427e-08, 'p_HEIDI': 0.003081132, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1819 | Q67 | What is the top-associated SNP of the gene MT1G in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene MT1G in Whole Brain meta-analysis mQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MT1G" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_557408', 'topRSID': 'rs7194895', 'Disease': 'PSP', 'Gene': 'MT1G', 'p_SMR_multi': 0.1806736, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1374 | Q67 | What is the top-associated SNP of the gene RP11-259G18.1 in Frontal Cortex BA9 eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.1 in Frontal Cortex BA9 eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 8.00e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%frontal cortex ba9 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1170876', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'RP11-259G18.1', 'p_SMR_multi': 7.996462e-11, 'p_HEIDI': 1.489663e-06, 'Omic_tissue': 'Frontal Cortex', 'Omic_type': 'Frontal Cortex BA9 eQTL', 'func_sig': 'association meets significance threshold but shows signs of li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1144 | Q67 | What is the top-associated SNP of the gene CD38 in Whole Brain eQTL omic data for PD and is it functionally significant? | The top-associated SNP for CD38 in Whole Brain eQTL omic data for PD is rs11724635, which has a multi-SNP SMR p-value of 2.16e-07 and a HEIDI of 0.95, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CD38" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1635910', 'topRSID': 'rs11724635', 'Disease': 'PD', 'Gene': 'CD38', 'p_SMR_multi': 2.157054e-07, 'p_HEIDI': 0.9490307, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.367 | Q67 | What is the top-associated SNP of the gene AP4M1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for AP4M1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs10281368, which has a multi-SNP SMR p-value of 1.58e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AP4M1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1392618', 'topRSID': 'rs10281368', 'Disease': 'AD', 'Gene': 'AP4M1', 'p_SMR_multi': 1.580094e-08, 'p_HEIDI': 3.17621e-06, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thresh... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1790 | Q67 | What is the top-associated SNP of the gene SNCA in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for SNCA in Whole Blood mQTL omic data for PD is rs1372520, which has a multi-SNP SMR p-value of 4.73e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SNCA" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_998609', 'topRSID': 'rs2301134', 'Disease': 'PD', 'Gene': 'SNCA', 'p_SMR_multi': 1.478211e-12, 'p_HEIDI': 1.830236e-18, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1208 | Q67 | What is the top-associated SNP of the gene MAPT-AS1 in Caudate Basal Ganglia eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT-AS1 in Caudate Basal Ganglia eQTL omic data for PSP is rs393152, which has a multi-SNP SMR p-value of 1.59e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT-AS1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1283701', 'topRSID': 'rs393152', 'Disease': 'PSP', 'Gene': 'MAPT-AS1', 'p_SMR_multi': 1.594923e-09, 'p_HEIDI': 4.702647e-06, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs o... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1035 | Q67 | What is the top-associated SNP of the gene CNN2 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for CNN2 in Whole Blood eQTL eQTLgen omic data for AD is rs113337161, which has a multi-SNP SMR p-value of 3.83e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CNN2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1503131', 'topRSID': 'rs113337161', 'Disease': 'AD', 'Gene': 'CNN2', 'p_SMR_multi': 3.829816e-14, 'p_HEIDI': 8.598535e-10, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1039 | Q67 | What is the top-associated SNP of the gene C16orf93 in Whole Brain eQTL omic data for PD and is it functionally significant? | The top-associated SNP for C16orf93 in Whole Brain eQTL omic data for PD is rs885107, which has a multi-SNP SMR p-value of 1.69e-07 and a HEIDI of 0.19, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C16orf93" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1639759', 'topRSID': 'rs885107', 'Disease': 'PD', 'Gene': 'C16orf93', 'p_SMR_multi': 1.689818e-07, 'p_HEIDI': 0.1877494, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1761 | Q67 | What is the top-associated SNP of the gene TBC1D16 in Whole Brain meta-analysis mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene TBC1D16 in Whole Brain meta-analysis mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TBC1D16" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_304738', 'topRSID': 'rs8074418', 'Disease': 'FTD', 'Gene': 'TBC1D16', 'p_SMR_multi': 0.1752997, 'p_HEIDI': 0.03183214, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_tex... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1357 | Q67 | What is the top-associated SNP of the gene RHCG in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene RHCG in Multi Ancestry Whole Brain Meta-analysis eQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RHCG" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1405765', 'topRSID': 'rs182317', 'Disease': 'ALS', 'Gene': 'RHCG', 'p_SMR_multi': 0.564286, 'p_HEIDI': 0.2664584, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1875 | Q67 | What is the top-associated SNP of the gene HOXA2 in Whole Blood eQTL GTEx omic data for ALS and is it functionally significant? | There are no SNPs within the gene HOXA2 in Whole Blood eQTL GTEx omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "HOXA2" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1656327', 'topRSID': 'rs2960785', 'Disease': 'ALS', 'Gene': 'HOXA2', 'p_SMR_multi': 0.3383717, 'p_HEIDI': 0.04787267, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.672 | Q67 | What is the top-associated SNP of the gene CRHR1 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for CRHR1 in Whole Brain meta-analysis mQTL omic data for PD is rs241028, which has a multi-SNP SMR p-value of 5.91e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491090', 'topRSID': 'rs878888', 'Disease': 'PD', 'Gene': 'CRHR1', 'p_SMR_multi': 1.344956e-12, 'p_HEIDI': 0.1584008, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_4910... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.369 | Q67 | What is the top-associated SNP of the gene GAK in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for GAK in Whole Blood mQTL omic data for PD is rs6837528, which has a multi-SNP SMR p-value of 1.02e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GAK" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996273', 'topRSID': 'rs12651271', 'Disease': 'PD', 'Gene': 'GAK', 'p_SMR_multi': 6.180527e-09, 'p_HEIDI': 3.619298e-07, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.80 | Q67 | What is the top-associated SNP of the gene YPEL3 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for YPEL3 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs12444973, which has a multi-SNP SMR p-value of 1.35e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "YPEL3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1396164', 'topRSID': 'rs12444973', 'Disease': 'AD', 'Gene': 'YPEL3', 'p_SMR_multi': 1.349949e-07, 'p_HEIDI': 9.943744e-09, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thres... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.28 | Q67 | What is the top-associated SNP of the gene RP11-347C12.2 in Prefrontal Cortex eQTL omic data for AD and is it functionally significant? | The top-associated SNP for RP11-347C12.2 in Prefrontal Cortex eQTL omic data for AD is rs11644392, which has a multi-SNP SMR p-value of 2.13e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-347C12.2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1202454', 'topRSID': 'rs11644392', 'Disease': 'AD', 'Gene': 'RP11-347C12.2', 'p_SMR_multi': 2.134238e-06, 'p_HEIDI': 0.0001473883, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'association meets significance threshold but shows signs of ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1438 | Q67 | What is the top-associated SNP of the gene LOC283174 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for LOC283174 in Whole Brain meta-analysis mQTL omic data for PD is rs35375713, which has a multi-SNP SMR p-value of 9.08e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LOC283174" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_470333', 'topRSID': 'rs35375713', 'Disease': 'PD', 'Gene': 'LOC283174', 'p_SMR_multi': 9.076681e-08, 'p_HEIDI': 1.240492e-05, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.531 | Q67 | What is the top-associated SNP of the gene SNX31 in Cortex eQTL metaBrain omic data for AD and is it functionally significant? | The top-associated SNP for SNX31 in Cortex eQTL metaBrain omic data for AD is rs1693568, which has a multi-SNP SMR p-value of 1.78e-06 and a HEIDI of 0.58, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SNX31" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1109774', 'topRSID': 'rs1693568', 'Disease': 'AD', 'Gene': 'SNX31', 'p_SMR_multi': 1.780954e-06, 'p_HEIDI': 0.5810352, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1836 | Q67 | What is the top-associated SNP of the gene CR1 in Cortex eQTL GTEx omic data for AD and is it functionally significant? | The top-associated SNP for CR1 in Cortex eQTL GTEx omic data for AD is rs679515, which has a multi-SNP SMR p-value of 4.46e-08 and a HEIDI of 0.96, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CR1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cortex eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1244290', 'topRSID': 'rs679515', 'Disease': 'AD', 'Gene': 'CR1', 'p_SMR_multi': 4.463872e-08, 'p_HEIDI': 0.9563398, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL GTEx', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.56 | Q67 | What is the top-associated SNP of the gene PCGF3 in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for PCGF3 in Whole Blood eQTL eQTLgen omic data for PD is rs3775142, which has a multi-SNP SMR p-value of 1.03e-06 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PCGF3" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1555634', 'topRSID': 'rs3775142', 'Disease': 'PD', 'Gene': 'PCGF3', 'p_SMR_multi': 1.03112e-06, 'p_HEIDI': 0.02392648, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.645 | Q67 | What is the top-associated SNP of the gene TRAPPC6A in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for TRAPPC6A in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs75858218, which has a multi-SNP SMR p-value of 2.76e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TRAPPC6A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 1... | [{'UUID': 'NDD_SMR_genes_all_update_text_1397653', 'topRSID': 'rs75858218', 'Disease': 'AD', 'Gene': 'TRAPPC6A', 'p_SMR_multi': 2.760943e-09, 'p_HEIDI': 0.004342879, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thr... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.306 | Q67 | What is the top-associated SNP of the gene FAM153B in Prefrontal Cortex eQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene FAM153B in Prefrontal Cortex eQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FAM153B" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1197883', 'topRSID': 'rs13190441', 'Disease': 'AD', 'Gene': 'FAM153B', 'p_SMR_multi': 0.673851, 'p_HEIDI': 0.1554468, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.725 | Q67 | What is the top-associated SNP of the gene HS3ST1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for HS3ST1 in Whole Blood mQTL omic data for AD is rs4635810, which has a multi-SNP SMR p-value of 9.79e-08 and a HEIDI of 0.48, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "HS3ST1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_658578', 'topRSID': 'rs2904297', 'Disease': 'AD', 'Gene': 'HS3ST1', 'p_SMR_multi': 6.832539e-08, 'p_HEIDI': 0.2494245, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_658581', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.631 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 1.61e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560864', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'MAPT', 'p_SMR_multi': 2.100115e-44, 'p_HEIDI': 0.01425494, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_56... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.8 | Q67 | What is the top-associated SNP of the gene DEXI in Whole Brain eQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene DEXI in Whole Brain eQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DEXI" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1617797', 'topRSID': 'rs6498135', 'Disease': 'ALS', 'Gene': 'DEXI', 'p_SMR_multi': 0.2694795, 'p_HEIDI': 0.3943209, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.810 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Skeletal Muscle eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Skeletal Muscle eQTL omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 1.31e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1370546', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 1.30958e-15, 'p_HEIDI': 0.007723259, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1058 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Brain meta-analysis mQTL omic data for PSP is rs8070723, which has a multi-SNP SMR p-value of 8.51e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560883', 'topRSID': 'rs8070723', 'Disease': 'PSP', 'Gene': 'KANSL1', 'p_SMR_multi': 4.848303e-12, 'p_HEIDI': 2.303492e-08, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.340 | Q67 | What is the top-associated SNP of the gene KCNK15 in Whole Blood mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene KCNK15 in Whole Blood mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KCNK15" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_717905', 'topRSID': 'rs1980577', 'Disease': 'ALS', 'Gene': 'KCNK15', 'p_SMR_multi': 0.03606374, 'p_HEIDI': 0.02369113, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_717907', 'to... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.48 | Q67 | What is the top-associated SNP of the gene IDUA in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for IDUA in Whole Brain meta-analysis mQTL omic data for PD is rs3806756, which has a multi-SNP SMR p-value of 2.02e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IDUA" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_429873', 'topRSID': 'rs1051613', 'Disease': 'PD', 'Gene': 'IDUA', 'p_SMR_multi': 4.554749e-13, 'p_HEIDI': 2.213052e-05, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1481 | Q67 | What is the top-associated SNP of the gene MAPT-AS1 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT-AS1 in Whole Brain meta-analysis mQTL omic data for PD is rs242937, which has a multi-SNP SMR p-value of 1.40e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491096', 'topRSID': 'rs56280951', 'Disease': 'PD', 'Gene': 'MAPT-AS1', 'p_SMR_multi': 3.97087e-15, 'p_HEIDI': 0.001150121, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.109 | Q67 | What is the top-associated SNP of the gene AC018638.1 in Cerebellar Hemisphere eQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene AC018638.1 in Cerebellar Hemisphere eQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AC018638.1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1172903', 'topRSID': 'rs6945126', 'Disease': 'AD', 'Gene': 'AC018638.1', 'p_SMR_multi': 0.6514729, 'p_HEIDI': 0.4020462, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.353 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PD is rs62063271, which has a multi-SNP SMR p-value of 9.22e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948891', 'topRSID': 'rs62063271', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 6.382411e-15, 'p_HEIDI': 2.368028e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.241 | Q67 | What is the top-associated SNP of the gene MINA in Whole Blood mQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene MINA in Whole Blood mQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MINA" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1033714', 'topRSID': 'rs9877544', 'Disease': 'PSP', 'Gene': 'MINA', 'p_SMR_multi': 0.7666248, 'p_HEIDI': 0.9760228, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1033715', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.216 | Q67 | What is the top-associated SNP of the gene TMEM175 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for TMEM175 in Whole Blood mQTL omic data for PD is rs6813110, which has a multi-SNP SMR p-value of 2.62e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TMEM175" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996283', 'topRSID': 'rs6813110', 'Disease': 'PD', 'Gene': 'TMEM175', 'p_SMR_multi': 2.618289e-11, 'p_HEIDI': 0.0001221027, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1827 | Q67 | What is the top-associated SNP of the gene KANSL1 in Cortex eQTL GTEx omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1 in Cortex eQTL GTEx omic data for PSP is rs17692129, which has a multi-SNP SMR p-value of 1.58e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cortex eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1264981', 'topRSID': 'rs17692129', 'Disease': 'PSP', 'Gene': 'KANSL1', 'p_SMR_multi': 1.57619e-10, 'p_HEIDI': 3.189608e-08, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequi... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1138 | Q67 | What is the top-associated SNP of the gene GAK in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for GAK in Whole Brain meta-analysis mQTL omic data for PD is rs11248057, which has a multi-SNP SMR p-value of 3.29e-10 and a HEIDI of 0.04, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GAK" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_429832', 'topRSID': 'rs11248057', 'Disease': 'PD', 'Gene': 'GAK', 'p_SMR_multi': 1.488653e-10, 'p_HEIDI': 1.165356e-06, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.800 | Q67 | What is the top-associated SNP of the gene ZNF503-AS2 in Whole Blood mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene ZNF503-AS2 in Whole Blood mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZNF503-AS2" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_741906', 'topRSID': 'rs1897191', 'Disease': 'ALS', 'Gene': 'ZNF503-AS2', 'p_SMR_multi': 0.4778635, 'p_HEIDI': 0.4602812, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_741907', '... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1123 | Q67 | What is the top-associated SNP of the gene ADCY10P1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for ADCY10P1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs62396343, which has a multi-SNP SMR p-value of 6.49e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ADCY10P1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 1... | [{'UUID': 'NDD_SMR_genes_all_update_text_1391979', 'topRSID': 'rs62396343', 'Disease': 'AD', 'Gene': 'ADCY10P1', 'p_SMR_multi': 6.486329e-07, 'p_HEIDI': 1.171977e-07, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance th... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1583 | Q67 | What is the top-associated SNP of the gene C6orf10 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for C6orf10 in Whole Blood mQTL omic data for AD is rs116667074, which has a multi-SNP SMR p-value of 6.45e-08 and a HEIDI of 0.04, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C6orf10" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_621662', 'topRSID': 'rs35265698', 'Disease': 'AD', 'Gene': 'C6orf10', 'p_SMR_multi': 2.929935e-08, 'p_HEIDI': 2.344082e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1672 | Q67 | What is the top-associated SNP of the gene RP11-410E4.1 in Hypothalamus eQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene RP11-410E4.1 in Hypothalamus eQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-410E4.1" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%hypothalamus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1459326', 'topRSID': 'rs6434177', 'Disease': 'LBD', 'Gene': 'RP11-410E4.1', 'p_SMR_multi': 0.6958396, 'p_HEIDI': 0.8495856, 'Omic_tissue': 'Hypothalamus', 'Omic_type': 'Hypothalamus eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.529 | Q67 | What is the top-associated SNP of the gene CRHR1-IT1 in Hypothalamus eQTL omic data for PD and is it functionally significant? | The top-associated SNP for CRHR1-IT1 in Hypothalamus eQTL omic data for PD is rs4630591, which has a multi-SNP SMR p-value of 2.35e-11 and a HEIDI of 0.53, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1-IT1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%hypothalamus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1462892', 'topRSID': 'rs4630591', 'Disease': 'PD', 'Gene': 'CRHR1-IT1', 'p_SMR_multi': 2.353776e-11, 'p_HEIDI': 0.5333156, 'Omic_tissue': 'Hypothalamus', 'Omic_type': 'Hypothalamus eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.235 | Q67 | What is the top-associated SNP of the gene GAK in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for GAK in Whole Brain meta-analysis mQTL omic data for PD is rs11248057, which has a multi-SNP SMR p-value of 6.95e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GAK" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_429832', 'topRSID': 'rs11248057', 'Disease': 'PD', 'Gene': 'GAK', 'p_SMR_multi': 1.488653e-10, 'p_HEIDI': 1.165356e-06, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.651 | Q67 | What is the top-associated SNP of the gene RP11-707O23.5 in Putamen Basal Ganglia eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-707O23.5 in Putamen Basal Ganglia eQTL omic data for PD is rs56082319, which has a multi-SNP SMR p-value of 3.30e-11 and a HEIDI of 0.72, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-707O23.5" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1594921', 'topRSID': 'rs56082319', 'Disease': 'PD', 'Gene': 'RP11-707O23.5', 'p_SMR_multi': 3.303079e-11, 'p_HEIDI': 0.7236853, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1509 | Q67 | What is the top-associated SNP of the gene TAP2 in Whole Brain eQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene TAP2 in Whole Brain eQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TAP2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1636622', 'topRSID': 'rs17034', 'Disease': 'PD', 'Gene': 'TAP2', 'p_SMR_multi': 0.5196493, 'p_HEIDI': 0.1609728, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.539 | Q67 | What is the top-associated SNP of the gene FAM200B in Whole Brain eQTL omic data for PD and is it functionally significant? | The top-associated SNP for FAM200B in Whole Brain eQTL omic data for PD is rs6839654, which has a multi-SNP SMR p-value of 1.72e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FAM200B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1635909', 'topRSID': 'rs6839654', 'Disease': 'PD', 'Gene': 'FAM200B', 'p_SMR_multi': 1.722494e-06, 'p_HEIDI': 0.003154015, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1753 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 1.17e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560864', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'MAPT', 'p_SMR_multi': 2.100115e-44, 'p_HEIDI': 0.01425494, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_56... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.610 | Q67 | What is the top-associated SNP of the gene SNCA in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for SNCA in Whole Blood mQTL omic data for PD is rs1372520, which has a multi-SNP SMR p-value of 1.54e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SNCA" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_998609', 'topRSID': 'rs2301134', 'Disease': 'PD', 'Gene': 'SNCA', 'p_SMR_multi': 1.478211e-12, 'p_HEIDI': 1.830236e-18, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1780 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Liver eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Liver eQTL omic data for PD is rs9468, which has a multi-SNP SMR p-value of 2.20e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%liver eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1476427', 'topRSID': 'rs9468', 'Disease': 'PD', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 2.195508e-12, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Liver', 'Omic_type': 'Liver eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1083 | Q67 | What is the top-associated SNP of the gene HCG4 in Whole Blood mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene HCG4 in Whole Blood mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "HCG4" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_847274', 'topRSID': 'rs147376303', 'Disease': 'LBD', 'Gene': 'HCG4', 'p_SMR_multi': 0.0736651, 'p_HEIDI': 0.3038184, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_847270', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1407 | Q67 | What is the top-associated SNP of the gene JAKMIP3 in Substantia nigra eQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene JAKMIP3 in Substantia nigra eQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "JAKMIP3" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%substantia nigra eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1452284', 'topRSID': 'rs7096456', 'Disease': 'PSP', 'Gene': 'JAKMIP3', 'p_SMR_multi': 0.006893757, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Substantia nigra', 'Omic_type': 'Substantia nigra eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.62 | Q67 | What is the top-associated SNP of the gene ZNF311 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for ZNF311 in Whole Blood mQTL omic data for AD is rs142403264, which has a multi-SNP SMR p-value of 2.47e-07 and a HEIDI of 0.14, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZNF311" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_619798', 'topRSID': 'rs142403264', 'Disease': 'AD', 'Gene': 'ZNF311', 'p_SMR_multi': 2.474527e-07, 'p_HEIDI': 0.1408498, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_619800', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1643 | Q67 | What is the top-associated SNP of the gene PM20D1 in Cortex eQTL metaBrain omic data for PD and is it functionally significant? | The top-associated SNP for PM20D1 in Cortex eQTL metaBrain omic data for PD is rs9438393, which has a multi-SNP SMR p-value of 6.36e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PM20D1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1142766', 'topRSID': 'rs9438393', 'Disease': 'PD', 'Gene': 'PM20D1', 'p_SMR_multi': 6.359165e-07, 'p_HEIDI': 1.943967e-05, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.95 | Q67 | What is the top-associated SNP of the gene APOE in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | The top-associated SNP for APOE in Whole Brain meta-analysis mQTL omic data for LBD is rs7259620, which has a multi-SNP SMR p-value of 1.35e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APOE" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_402973', 'topRSID': 'rs7259620', 'Disease': 'LBD', 'Gene': 'APOE', 'p_SMR_multi': 1.514884e-15, 'p_HEIDI': 8.672375000000001e-28, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.673 | Q67 | What is the top-associated SNP of the gene TMEM175 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for TMEM175 in Whole Brain meta-analysis mQTL omic data for PD is rs11729289, which has a multi-SNP SMR p-value of 2.36e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TMEM175" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_429841', 'topRSID': 'rs10008187', 'Disease': 'PD', 'Gene': 'TMEM175', 'p_SMR_multi': 4.414637e-10, 'p_HEIDI': 0.4333231, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.284 | Q67 | What is the top-associated SNP of the gene SNCA in Whole Blood mQTL omic data for LBD and is it functionally significant? | The top-associated SNP for SNCA in Whole Blood mQTL omic data for LBD is rs2301134, which has a multi-SNP SMR p-value of 3.12e-10 and a HEIDI of 0.86, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SNCA" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_934862', 'topRSID': 'rs2301134', 'Disease': 'LBD', 'Gene': 'SNCA', 'p_SMR_multi': 3.123872e-10, 'p_HEIDI': 0.8604982, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_934864', 'topRSID... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1796 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Caudate Basal Ganglia eQTL omic data for AD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Caudate Basal Ganglia eQTL omic data for AD is rs8073146, which has a multi-SNP SMR p-value of 2.96e-06 and a HEIDI of 0.49, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1268123', 'topRSID': 'rs8073146', 'Disease': 'AD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 2.960964e-06, 'p_HEIDI': 0.4893544, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.364 | Q67 | What is the top-associated SNP of the gene GPR20 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene GPR20 in Whole Brain meta-analysis mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GPR20" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_456233', 'topRSID': 'rs7823363', 'Disease': 'PD', 'Gene': 'GPR20', 'p_SMR_multi': 0.2833181, 'p_HEIDI': 0.9675483, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_45... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1468 | Q67 | What is the top-associated SNP of the gene ZKSCAN3 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for ZKSCAN3 in Whole Blood eQTL eQTLgen omic data for AD is rs213230, which has a multi-SNP SMR p-value of 1.75e-06 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZKSCAN3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1494675', 'topRSID': 'rs213230', 'Disease': 'AD', 'Gene': 'ZKSCAN3', 'p_SMR_multi': 1.752465e-06, 'p_HEIDI': 0.01027817, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1169 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Cortex eQTL metaBrain omic data for PSP and is it functionally significant? | The top-associated SNP for ARHGAP27 in Cortex eQTL metaBrain omic data for PSP is rs1230103, which has a multi-SNP SMR p-value of 1.52e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1154392', 'topRSID': 'rs1230103', 'Disease': 'PSP', 'Gene': 'ARHGAP27', 'p_SMR_multi': 1.523917e-09, 'p_HEIDI': 4.082213e-05, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.854 | Q67 | What is the top-associated SNP of the gene AC135048.1 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for AC135048.1 in Whole Brain meta-analysis mQTL omic data for PD is rs7199949, which has a multi-SNP SMR p-value of 3.21e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AC135048.1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_485448', 'topRSID': 'rs7199949', 'Disease': 'PD', 'Gene': 'AC135048.1', 'p_SMR_multi': 3.211323e-08, 'p_HEIDI': 0.0005010102, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1379 | Q67 | What is the top-associated SNP of the gene CD38 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD and is it functionally significant? | The top-associated SNP for CD38 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD is rs3213710, which has a multi-SNP SMR p-value of 1.47e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CD38" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1430256', 'topRSID': 'rs3213710', 'Disease': 'PD', 'Gene': 'CD38', 'p_SMR_multi': 1.473525e-11, 'p_HEIDI': 2.838263e-13, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thresho... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.113 | Q67 | What is the top-associated SNP of the gene MADD in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for MADD in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs35233100, which has a multi-SNP SMR p-value of 1.67e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MADD" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1394231', 'topRSID': 'rs35233100', 'Disease': 'AD', 'Gene': 'MADD', 'p_SMR_multi': 1.671309e-06, 'p_HEIDI': 0.0008438054, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thresh... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.43 | Q67 | What is the top-associated SNP of the gene PM20D1 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for PM20D1 in Whole Blood mQTL omic data for PD is rs1772143, which has a multi-SNP SMR p-value of 7.75e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PM20D1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_944692', 'topRSID': 'rs823080', 'Disease': 'PD', 'Gene': 'PM20D1', 'p_SMR_multi': 7.078994e-07, 'p_HEIDI': 1.577211e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.128 | Q67 | What is the top-associated SNP of the gene TREM2 in Cortex eQTL metaBrain omic data for AD and is it functionally significant? | The top-associated SNP for TREM2 in Cortex eQTL metaBrain omic data for AD is rs9394778, which has a multi-SNP SMR p-value of 6.31e-07 and a HEIDI of 0.7, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TREM2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1109138', 'topRSID': 'rs9394778', 'Disease': 'AD', 'Gene': 'TREM2', 'p_SMR_multi': 6.308333e-07, 'p_HEIDI': 0.7032683, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.207 | Q67 | What is the top-associated SNP of the gene KANSL1 in Spinalcord eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1 in Spinalcord eQTL omic data for PD is rs199451, which has a multi-SNP SMR p-value of 1.28e-06 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%spinalcord eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_30028', 'topRSID': 'rs199451', 'Disease': 'PD', 'Gene': 'KANSL1', 'p_SMR_multi': 1.277333e-06, 'p_HEIDI': 0.01301229, 'Omic_tissue': 'Spinalcord', 'Omic_type': 'Spinalcord eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.53 | Q67 | What is the top-associated SNP of the gene JAZF1-AS1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for JAZF1-AS1 in Whole Blood mQTL omic data for AD is rs849336, which has a multi-SNP SMR p-value of 2.37e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "JAZF1-AS1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_584300', 'topRSID': 'rs849336', 'Disease': 'AD', 'Gene': 'JAZF1-AS1', 'p_SMR_multi': 2.371217e-06, 'p_HEIDI': 0.001251494, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.551 | Q67 | What is the top-associated SNP of the gene BIN1 in Cerebellum eQTL omic data for AD and is it functionally significant? | The top-associated SNP for BIN1 in Cerebellum eQTL omic data for AD is rs62158731, which has a multi-SNP SMR p-value of 1.64e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "BIN1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1686596', 'topRSID': 'rs62158731', 'Disease': 'AD', 'Gene': 'BIN1', 'p_SMR_multi': 1.637274e-08, 'p_HEIDI': 1.114888e-12, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.71 | Q67 | What is the top-associated SNP of the gene CRHR1-IT1 in Whole Blood eQTL eQTLgen omic data for PSP and is it functionally significant? | The top-associated SNP for CRHR1-IT1 in Whole Blood eQTL eQTLgen omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 1.76e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1-IT1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1579419', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'CRHR1-IT1', 'p_SMR_multi': 1.757151e-15, 'p_HEIDI': 8.855662e-11, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ L... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1816 | Q67 | What is the top-associated SNP of the gene RP11-521O16.1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for RP11-521O16.1 in Whole Blood mQTL omic data for AD is rs2404175, which has a multi-SNP SMR p-value of 4.35e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-521O16.1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_631109', 'topRSID': 'rs77571924', 'Disease': 'AD', 'Gene': 'RP11-521O16.1', 'p_SMR_multi': 4.4846810000000005e-17, 'p_HEIDI': 1.460436e-09, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1745 | Q67 | What is the top-associated SNP of the gene DND1P1 in Frontal Cortex BA9 eQTL omic data for PD and is it functionally significant? | The top-associated SNP for DND1P1 in Frontal Cortex BA9 eQTL omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 1.58e-10 and a HEIDI of 0.92, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DND1P1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%frontal cortex ba9 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1168832', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'DND1P1', 'p_SMR_multi': 1.576563e-10, 'p_HEIDI': 0.9171828, 'Omic_tissue': 'Frontal Cortex', 'Omic_type': 'Frontal Cortex BA9 eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.186 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Blood mQTL omic data for PD is rs35937770, which has a multi-SNP SMR p-value of 1.34e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948907', 'topRSID': 'rs2532233', 'Disease': 'PD', 'Gene': 'KANSL1', 'p_SMR_multi': 1.024112e-14, 'p_HEIDI': 2.989456e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.140 | Q67 | What is the top-associated SNP of the gene LRRC37A4P in Caudate Basal Ganglia eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A4P in Caudate Basal Ganglia eQTL omic data for PD is rs62062813, which has a multi-SNP SMR p-value of 1.24e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A4P" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1281349', 'topRSID': 'rs62062813', 'Disease': 'PD', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 1.242453e-12, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs of l... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.907 | Q67 | What is the top-associated SNP of the gene FNTA in Tibial Nerve eQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene FNTA in Tibial Nerve eQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FNTA" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1316049', 'topRSID': 'rs4623474', 'Disease': 'LBD', 'Gene': 'FNTA', 'p_SMR_multi': 0.9135951, 'p_HEIDI': 0.3029812, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.803 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Blood mQTL omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 3.18e-40 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041709', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'ARHGAP27', 'p_SMR_multi': 3.175631e-40, 'p_HEIDI': 2.761191e-07, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.135 | Q67 | What is the top-associated SNP of the gene PTPN3 in Whole Blood mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene PTPN3 in Whole Blood mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PTPN3" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_967190', 'topRSID': 'rs62577666', 'Disease': 'PD', 'Gene': 'PTPN3', 'p_SMR_multi': 0.8553212, 'p_HEIDI': 0.8848951, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_967188', 'topRS... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.83 | Q67 | What is the top-associated SNP of the gene UFSP1 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for UFSP1 in Whole Blood eQTL eQTLgen omic data for AD is rs7783457, which has a multi-SNP SMR p-value of 5.12e-09 and a HEIDI of 0.62, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "UFSP1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1495826', 'topRSID': 'rs7783457', 'Disease': 'AD', 'Gene': 'UFSP1', 'p_SMR_multi': 5.120394e-09, 'p_HEIDI': 0.6177553, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1541 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Amygdala eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Amygdala eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 3.76e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%amygdala eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1604713', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 3.764575e-14, 'p_HEIDI': 2.388099e-09, 'Omic_tissue': 'Amygdala', 'Omic_type': 'Amygdala eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.547 | Q67 | What is the top-associated SNP of the gene TAS2R63P in Prefrontal Cortex eQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene TAS2R63P in Prefrontal Cortex eQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TAS2R63P" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1230281', 'topRSID': 'rs2122616', 'Disease': 'LBD', 'Gene': 'TAS2R63P', 'p_SMR_multi': 0.2598016, 'p_HEIDI': 0.06753201, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1596 | Q67 | What is the top-associated SNP of the gene INO80E in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for INO80E in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs8054556, which has a multi-SNP SMR p-value of 3.44e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "INO80E" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1396161', 'topRSID': 'rs8054556', 'Disease': 'AD', 'Gene': 'INO80E', 'p_SMR_multi': 3.439942e-08, 'p_HEIDI': 9.611447e-09, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thres... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.992 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Putamen Basal Ganglia eQTL omic data for AD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Putamen Basal Ganglia eQTL omic data for AD is rs55942528, which has a multi-SNP SMR p-value of 2.72e-06 and a HEIDI of 0.8, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1584318', 'topRSID': 'rs55942528', 'Disease': 'AD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 2.716762e-06, 'p_HEIDI': 0.7963627, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.168 | Q67 | What is the top-associated SNP of the gene NSF in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for NSF in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PSP is rs4792831, which has a multi-SNP SMR p-value of 3.79e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NSF" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1444277', 'topRSID': 'rs4792831', 'Disease': 'PSP', 'Gene': 'NSF', 'p_SMR_multi': 3.792828e-07, 'p_HEIDI': 0.0006568263, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thresho... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.251 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 1.35e-40 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMI... | [{'UUID': 'NDD_SMR_genes_all_update_text_1444273', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 1.3471999999999999e-40, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significa... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.452 | Q67 | What is the top-associated SNP of the gene NOL9 in Whole Blood eQTL GTEx omic data for AD and is it functionally significant? | There are no SNPs within the gene NOL9 in Whole Blood eQTL GTEx omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NOL9" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1647109', 'topRSID': 'rs7517959', 'Disease': 'AD', 'Gene': 'NOL9', 'p_SMR_multi': 0.7316989, 'p_HEIDI': 0.7009923, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1148 | Q67 | What is the top-associated SNP of the gene STAG3 in Substantia nigra eQTL omic data for AD and is it functionally significant? | The top-associated SNP for STAG3 in Substantia nigra eQTL omic data for AD is rs1987580, which has a multi-SNP SMR p-value of 5.98e-07 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "STAG3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%substantia nigra eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1446227', 'topRSID': 'rs1987580', 'Disease': 'AD', 'Gene': 'STAG3', 'p_SMR_multi': 5.982321e-07, 'p_HEIDI': 0.01389594, 'Omic_tissue': 'Substantia nigra', 'Omic_type': 'Substantia nigra eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.865 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs55974014, which has a multi-SNP SMR p-value of 3.32e-07 and a HEIDI of 0.74, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT... | [{'UUID': 'NDD_SMR_genes_all_update_text_1396750', 'topRSID': 'rs55974014', 'Disease': 'AD', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 3.316083e-07, 'p_HEIDI': 0.7385473, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1233 | Q67 | What is the top-associated SNP of the gene INPP5D in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for INPP5D in Whole Blood mQTL omic data for AD is rs10933431, which has a multi-SNP SMR p-value of 5.83e-13 and a HEIDI of 0.31, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "INPP5D" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_633025', 'topRSID': 'rs10933431', 'Disease': 'AD', 'Gene': 'INPP5D', 'p_SMR_multi': 5.825275e-13, 'p_HEIDI': 0.312526, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_633024', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.100 | Q67 | What is the top-associated SNP of the gene RP11-259G18.2 in Cerebellar Hemisphere eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.2 in Cerebellar Hemisphere eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 6.14e-18 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1194218', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'RP11-259G18.2', 'p_SMR_multi': 6.139863e-18, 'p_HEIDI': 2.411918e-16, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'association meets significance threshold but shows s... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1974 | Q67 | What is the top-associated SNP of the gene TSPAN14 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for TSPAN14 in Whole Brain meta-analysis mQTL omic data for AD is rs4933390, which has a multi-SNP SMR p-value of 7.71e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TSPAN14" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_85783', 'topRSID': 'rs7086627', 'Disease': 'AD', 'Gene': 'TSPAN14', 'p_SMR_multi': 2.786675e-08, 'p_HEIDI': 0.001397175, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.744 | Q67 | What is the top-associated SNP of the gene SNCA in Whole Blood eQTL eQTLgen omic data for LBD and is it functionally significant? | The top-associated SNP for SNCA in Whole Blood eQTL eQTLgen omic data for LBD is rs2245801, which has a multi-SNP SMR p-value of 7.16e-10 and a HEIDI of 0.29, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SNCA" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1540410', 'topRSID': 'rs2245801', 'Disease': 'LBD', 'Gene': 'SNCA', 'p_SMR_multi': 7.155271e-10, 'p_HEIDI': 0.287884, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1252 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Anterior Cingulate Cortex BA24 eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Anterior Cingulate Cortex BA24 eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 3.64e-16 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%anterior cingulate cortex ba24 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1489538', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 3.635269e-16, 'p_HEIDI': 3.589355e-10, 'Omic_tissue': 'Anterior Cingulate Cortex BA24', 'Omic_type': 'Anterior Cingulate Cortex BA24 eQTL', 'func_sig': 'association meets significance thresho... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.105 | Q67 | What is the top-associated SNP of the gene APOC4 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for APOC4 in Whole Blood mQTL omic data for AD is rs5120, which has a multi-SNP SMR p-value of 3.10e-20 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APOC4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_637435', 'topRSID': 'rs5120', 'Disease': 'AD', 'Gene': 'APOC4', 'p_SMR_multi': 3.09724e-20, 'p_HEIDI': 3.551854e-17, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequili... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
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