0 stringlengths 12 494 | embeddings listlengths 384 384 |
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Stage\t1\n130-139\tmm\tHg\nor\n80-89\tmm\tHg\nStage\t2\n>130-139\tmm\tHg\nor\n>90\tmm\tHg\nSBP\n,\tSystolic\tblood\tpressure;\t\nDBP\n,\tDiastolic\tblood\tpressure.\nWhelton\tPK,\tet\tal:\t2017\tACC/AHA/AAPA/ABC/ACPM/APhA/ASH/ASPC/NMA/PCNA\tguideline\tfor\tthe\tprevention,\tdetection,\tevaluation\tand\nmanagement\tof\t... | [
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J\tAm\tColl\tCardiol\n\t71:\te127-e240,\t2018.\n*\nIndividuals\twith\tSBP\tand\tDBP\tin\t2\tcategories\tshould\tbe\tdesignated\tto\tthe\thigher\tblood\tpressure\tcategory.\tBlood\tpressure\tis\tbased\ton\tan\taverage\nof\t≥2\tcareful\treadings\tobtained\ton\t≥2\toccasions.\nThe\tclinical\tpractice\tguidelines\tfrom\tth... | [
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Evaluation,\tand\tManagement\tof\tHigh\tBlood\tPressure\tin\tAdults\t(\nWhelton\tet\tal,\t2018\n)\tstate\tthat\tthe\ncombination\tof\tdiet\tand\tlifestyle\ttherapy\tis\tespecially\tuseful\tin\tadults\tfor\tthe\tprevention\tof\nhypertension\tand\tfor\tthe\tmanagement\tof\televated\tblood\tpressure\tand\tstage\t1\thypert... | [
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clinical\tASCVD\tor\testimated\t10-year\tASCVD\trisk\tof\t≤10%\t(see\t\nhttp://tools.acc.org/ASCVD-Risk-\nEstimator-Plus/#!/calculate/estimate/\n).\tFor\tadults\twith\tstage\t1\thypertension\twith\tclinical\tASCVD\n\tor\nestimated\t10-year\trisk\tof\tASCVD\t≥10%\tor\tstage\t2\thypertension,\tthe\tACC/AHA\tguidelines | [
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recommends\tblood\tpressure–lowering\tmedication\tin\tcombination\twith\tnonpharmacotherapy\tfor\nprimary\tprevention\tof\tCVD.\tThe\tguidelines\talso\tcall\tfor\tindividuals\twith\tdiabetes,\tHF,\tand\tchronic\nkidney\tdisease\tto\tbe\ttreated\twith\tblood\tpressure–lowering\tmedication\twhen\ttheir\tblood\tpressure\n... | [
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exceeds\t130/80\tmm\tHg.\tThe\trecommendations\n\tare\tbased\ton\tclinical\tevidence\tshowing\tthat\tstricter\nguidelines\tfor\tthese\tpatients\tmay\tprevent\tacceleration\tof\ttarget\torgan\tdamage\t(kidney,\theart,\tand\npancreas)\tand\trelated\tcomorbidities.\tImportantly,\tthe\tguidelines\temphasize\tthat\tpeople\t... | [
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0.00662... |
blood\tpressure\tshould\tfollow\ta\thealthy\tdiet\tand\tlifestyle\talong\twith\tmedication\tmanagement.\tDiet | [
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and\tlifestyle\tmodifications\tare\timportant\n\tparts\tof\tprimary\tprevention\tof\thypertension.\nHypertension\tis\ta\tcommon\tpublic\thealth\tproblem\tin\tdeveloped\tcountries.\tIn\tthe\tUnited\tStates\tone\nin\tthree\tadults\thas\thigh\tblood\tpressure\t(\nCDC,\t2017\n).\tUntreated\thypertension\tleads\tto\tmany | [
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CDC,\t2017\n).\tUntreated\thypertension\tleads\tto\tmany\ndegenerative\tdiseases,\tincluding\tHF,\tend-stage\trenal\tdisease,\tand\tperipheral\tvascular\tdisease.\tIt\tis\noften\tcalled\ta\t“silent\tkiller”\tbecause\tpeople\twith\thypertension\n\tcan\tbe\tasymptomatic\tfor\tyears\tand\nthen\thave\ta\tfatal\tstroke\tor\... | [
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0.029278870... |
detected\tand\tusually\tcontrollable.\tSome\tof\tthe\tdecline\tin\tCVD\tmortality\tduring\tthe\tlast\ttwo\tdecades\nhas\tbeen\tattributed\tto\tthe\tincreased\tdetection\tand\tcontrol\tof\thypertension.\tThe\temphasis\ton\tlifestyle\nmodifications\thas\tgiven\tdiet\ta\tprominent\trole\tin\tthe\tprimary\tprevention\n\tan... | [
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and\tmanagement\tof\nhypertension.\nOf\tthose\tpersons\twith\thigh\tblood\tpressure,\t90%\tto\t95%\thave\t\nessential\thypertension\n(hypertension\tof\tunknown\tcause)\tor\tprimary\thypertension.\tThe\tcause\tinvolves\ta\tcomplex\tinteraction\nbetween\tpoor\tlifestyle\tchoices\tand\tgene\texpression.\tLifestyle\tfactor... | [
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include\tpoor\tdiet\t(i.e.,\thigh\tsodium,\tlow\tfruit\tand\tvegetable\tintake),\tsmoking,\tphysical\n\tinactivity,\nstress,\tand\tobesity.\tVascular\tinflammation\thas\talso\tbeen\timplicated\t(\nDe\tMiguel\tet\tal,\t2015\n).\tMany\ngenes\tplay\ta\trole\tin\thypertension;\tmost\trelate\tto\tthe\trenal\tor\tneuroendocr... | [
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pressure.\tGenome-wide\tassociation\tstudies\thave\trevealed\tmore\tthan\t100\tvariants\tassociated\twith\nblood\tpressure,\talthough\tcumulatively\tthese\texplain\tonly\ta\tsmall\tpercent\tof\tblood\tpressure\nvariability\n\t(\nSeidel\tand\tScholl,\t2017\n).\tThe\tmajority\tof\tthe\tgenetic\tcontributors\tto\tblood\tp... | [
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0.0486... |
regulation\tare\tcurrently\tunknown\t(see\t\nChapter\t6\n).\tHypertension\tthat\tarises\tas\tthe\tresult\tof\tanother\ndisease,\tusually\tendocrine,\tis\treferred\tto\tas\t\nsecondary\thypertension\n.\tDepending\ton\tthe\textent\tof\nthe\tunderlying\tdisease,\tsecondary\thypertension\tcan\tbe\tcured.\nPrevalence\tand\t... | [
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0.034... |
Prevalence\tand\tincidence\nApproximately\t85.7\tmillion\n\tAmerican\tadults\tage\t20\tand\tolder\thave\thypertension\tor\tare\ttaking\nantihypertensive\tmedication\t(\nBenjamin\tet\tal,\t2018\n).\tProjections\tshow\tthat\tby\t2030,\tprevalence\tof\nhypertension\twill\tincrease\tby\t8.4%\tfrom\t2013\testimates.\tNon-Hi... | [
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0.01916... |
age-adjusted\tprevalence\tof\thypertension\t(45.0%\tof\tmen;\t46.3%\tof\twomen)\tthan\tnon-Hispanic\twhites\n(34.5%\tof\tmen;\t32.3%\tof\twomen)\tand\tMexican\n\tAmericans\t(30.1%\tof\tmen;\t28.8%\tof\twomen)\n(\nBenjamin\tet\tal,\t2018\n).\tThe\tprevalence\tof\thigh\tblood\tpressure\tin\tblacks\tis\tone\tof\tthe\thigh... | [
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seen\tanywhere\tin\tthe\tworld.\tBecause\tblacks\tdevelop\thypertension\tearlier\tin\tlife\tand\tmaintain\thigher\nblood\tpressure\tlevels,\ttheir\trisk\tof\tfatal\tstroke,\theart\tdisease,\tor\tend-stage\tkidney\tdisease\tis\thigher\nthan\twhites\t(\nBenjamin\tet\tal,\t2018\n).\nA\tperson\tof\tany\n\tage\tcan\thave\th... | [
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0.0033693... |
elevated\tblood\tpressure\t(\nMa\tet\tal,\t2016\n;\t\nXi\tet\tal,\t2016\n).\tWith\taging,\tthe\tprevalence\tof\thigh\tblood\npressure\tincreases\t(\nFig.\t32.7\n).\tBefore\tthe\tage\tof\t45\tmore\tmen\tthan\twomen\thave\thigh\tblood\npressure,\tand\tafter\tage\t65\tthe\trates\tof\thigh\tblood\tpressure\tamong\twomen\ti... | [
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0.0373477935... |
surpass\tthose\tof\tthe\tmen\tin\ttheir\tgroup\n\t(\nGo\tet\tal,\t2014\n).\tBecause\tthe\tprevalence\tof\thypertension\nrises\twith\tincreasing\tage,\tmore\tthan\thalf\tthe\tolder\tadult\tpopulation\t(more\tthan\t65\tyears\tof\tage)\tin\nany\tracial\tgroup\thas\thypertension.\tAlthough\tlifestyle\tinterventions\ttarget... | [
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0.003710... |
reduce\tthe\tprevalence\tof\thypertension,\tearly\tintervention\tprograms\tprovide\tthe\tgreatest\tlong-term\npotential\tfor\treducing\toverall\tblood\tpressure-related\n\tcomplications\t(\nWhelton\tet\tal,\t2018\n).\nFIG.\t32.7\nAge-specific\tand\tage-adjusted\tprevalence\tof\thypertension\tin\tadults:\tUnited\tStates... | [
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2006.\n\tSource:\t(Ostchega\tY,\tet\tal:\t\nHypertension\tawareness,\ttreatment,\tand\tcontrol—continued\tdisparities\tin\tadults:\tUnited\tStates,\n2005-2006.\n\tNCHS\tdata\tbrief\tno.\t3,\tHyattsville,\tMd,\t2008,\tNational\tCenter\tfor\tHealth\tStatistics.)\nThe\trelationship\tbetween\tblood\tpressure\tand\trisk\tof... | [
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continuous\tand\tindependent\tof\nother\trisk\tfactors.\tThe\thigher\tthe\tblood\tpressure,\tthe\tgreater\tis\tthe\tchance\tof\ttarget\torgan\tdamage,\nincluding\tleft\tventricular\thypertrophy\t(LVH),\tHF,\tstroke,\tchronic\tkidney\tdisease,\tand\tretinopathy\n(\nBenjamin\tet\tal,\t2018\n).\tAs\tmany\tas\t13%\tof\tadu... | [
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0.05... |
hypertension,\twhich\tmeans\tthat\ttheir\tblood\tpressure\tremains\thigh\tdespite\tthe\n\tuse\tof\tthree\tor\tmore\nantihypertensive\tdrugs\tfrom\tdifferent\tclasses\t(\nWhelton\tet\tal,\t2018\n).\tTreatment-resistant\nhypertension\tputs\tan\tindividual\tat\tgreater\trisk\tof\ttarget\torgan\tdamage.\tOlder\tage\tand\to... | [
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0.03... |
two\tof\tthe\tstrongest\trisk\tfactors\tassociated\twith\tthe\tcondition.\tIdentification\tand\treversal\tof\tlifestyle\nfactors\tcontributing\tto\ttreatment\tresistance,\talong\twith\tdiagnosis\tand\tappropriate\n\ttreatment\tof | [
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0.03701164573431015,
0.026... |
secondary\tcauses\tand\tuse\tof\teffective\tmultidrug\tregimens,\tare\tessential\ttreatment\tstrategies.\nThe\tprevalence\tof\thypertension\tamong\tadults\twith\tdiabetes\tis\t80%\tand\thypertension\tis\tat\tleast\ntwice\tas\tcommon\tamong\tpersons\twith\ttype\t2\tdiabetes\tas\tpersons\tof\tthe\tsame\tage\twithout\tdia... | [
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0.0259796604514122,
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0.028200494... |
(\nWhelton\tet\tal,\t2018\n).\tAdults\twith\tdiabetes\thave\tCVD\tdeath\trates\ttwo\tto\tfour\ttimes\thigher\tthan\nadults\n\twithout\tdiabetes\t(\nBenjamin\tet\tal,\t2018\n).\tConsequently,\tnational\thealth\torganizations,\nincluding\tthe\tACC/AHA,\thave\tset\tthe\ttarget\tblood\tpressure\tgoal\tfor\tantihypertensive... | [
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0.040957942605018616,
0.0... |
individuals\twith\tdiabetes\tlower\tthan\tthat\trecommended\tfor\tthe\tgeneral\tpopulation,\twhich\tis\t140/90\nmm\tHg\t(\nWhelton\tet\tal,\t2018\n).\tIn\tadults\twith\tdiabetes\tand\thypertension,\tthe\tACC/AHA\trecommends\nantihypertensive\tdrug\n\ttreatment\tto\tbe\tinitiated\tat\ta\tblood\tpressure\tof\t130/80\tmm\... | [
0.015547188930213451,
0.005526753142476082,
0.01964414119720459,
-0.025089338421821594,
-0.1092250645160675,
0.005839566234499216,
0.08248156309127808,
0.03463052213191986,
-0.023476194590330124,
0.07959727197885513,
0.12402918189764023,
-0.028311215341091156,
0.012454789131879807,
0.01191... |
a\ttreatment\tgoal\tof\tless\tthan\t130/80\tmm\tHg.\tBlood\tpressure\tcontrol\tis\toften\tmore\tdifficult\tto\tachieve\nin\tpatients\twith\tdiabetes\tthan\tin\tthose\twithout\tdiabetes,\tnecessitating\tuse\tof\ta\tcombination\tof\tblood\npressure–lowering\tmedications\tin\tthe\tmajority\tof\tpatients\t(\nWhelton\tet\ta... | [
-0.004681976977735758,
-0.001335557783022523,
0.028136203065514565,
-0.01650911569595337,
-0.12107251584529877,
0.0021839404944330454,
0.06251975893974304,
0.04388530179858208,
0.03869897872209549,
0.01615237258374691,
0.09631435573101044,
0.014190682210028172,
0.04480297863483429,
0.02852... |
Whelton\tet\tal,\t2018\n).\nAlthough\thypertensive\tpatients\tare\n\toften\tasymptomatic,\thypertension\tis\tnot\ta\tbenign\tdisease.\nCardiac,\tcerebrovascular,\tand\trenal\tsystems\tare\taffected\tby\tchronically\televated\tblood\tpressure\n(\nTable\t32.2\n).\tHigh\tblood\tpressure\twas\tthe\tprimary\tor\ta\tcontribu... | [
-0.0026212972588837147,
-0.021495740860700607,
0.045978087931871414,
-0.02105577103793621,
-0.05719926208257675,
-0.011242261156439781,
0.07622802257537842,
0.04978802800178528,
-0.03303011134266853,
0.059506360441446304,
0.06983821094036102,
-0.0076611642725765705,
0.057758528739213943,
0... |
million\tU.S.\tdeaths\tin\t2009\t(\nBenjamin\tet\tal,\t2018\n).\tBetween\t2005\tand\t2015\tthe\tage-adjusted\tdeath\nrate\tfrom\thypertension\tincreased\tby\t10.5%;\toverall\n\tdeaths\tfrom\thypertension\tincreased\tby\t37.5%.\nDeath\trates\tfrom\thypertension\tare\tapproximately\tthree\ttimes\thigher\tin\tblacks\tthan... | [
-0.008366983383893967,
-0.01614377275109291,
0.009714830666780472,
0.01406886987388134,
-0.052749693393707275,
-0.009828450158238411,
0.10113292932510376,
0.09583988785743713,
-0.05242420732975006,
0.018935900181531906,
0.07067601382732391,
-0.05351266264915466,
0.07093548774719238,
-0.030... |
(\nBenjamin\tet\tal,\t2018\n).\tHypertension\tis\ta\tmajor\tcontributing\tfactor\tto\tatherosclerosis,\tstroke,\trenal\nfailure,\tand\tMI.\tFactors\tassociated\twith\ta\tpoor\tprognosis\tin\thypertension\tare\tshown\tin\t\nBox\t32.6\n.\nTABLE\t32.2\nManifestations\tof\tTarget\tOrgan\tDisease\tfrom\tHypertension\nOrgan\... | [
-0.0182321947067976,
-0.044430918991565704,
0.058123525232076645,
-0.0011371469590812922,
-0.03542739152908325,
0.010961167514324188,
0.06445574760437012,
0.024715011939406395,
-0.04489170387387276,
0.01947103627026081,
0.0894894003868103,
-0.029231110587716103,
0.040418073534965515,
0.010... |
Organ\tSystem\nManifestations\nCardiac\nClinical,\telectrocardiographic,\tor\tradiologic\tevidence\tof\tarterial\twall\tthickening\tleft\nventricular\thypertrophy;\tleft\tventricular\tmalfunction\tor\tcardiac\tfailure\nCerebrovascular\nTransient\tischemic\tattack\tor\tstroke\nPeripheral\nAbsence\tof\tone\tor\tmore\tpul... | [
-0.0007597797666676342,
-0.0787242203950882,
0.02553729899227619,
-0.049156803637742996,
-0.11604081094264984,
-0.027232307940721512,
0.017758702859282494,
-0.010540313087403774,
-0.01234796829521656,
0.039959754794836044,
0.08966264128684998,
-0.02683025784790516,
0.024247217923402786,
0.... |
Index\t<0.9\nRenal\nSerum\tcreatinine\televated:\n\tmen\t1.3-1.5\tmg/dL,\twomen\t1.2-1.4\tmg/dL\nCalculated\tGFR\t<60\tmL/min/1.73\tm\n2\nElevated\talbumin\texcretion\nRetinopathy\nHemorrhages\tor\texudates,\twith\tor\twithout\tpapilledema\nGFR\n,\tGlomerular\tfiltration\trate.\nAdapted\tfrom\tSchmieder\tR:\tEnd\torgan... | [
-0.004607679322361946,
-0.062513567507267,
0.028813382610678673,
0.046076759696006775,
-0.05344390496611595,
-0.06075810268521309,
0.047521695494651794,
0.09968981146812439,
0.000990640139207244,
0.007184781599789858,
0.07501167804002762,
0.009444908238947392,
0.07715253531932831,
0.048694... |
Dtsch\tArztebl\n\t107:866,\t2010.\nBOX\t32.6\nRisk\tFactors\tand\tAdverse\tPrognosis\tin\tHypertension\nRisk\tfactors\nBlack\trace\nYouth\nMale\tgender\nPersistent\tdiastolic\tpressure\t>115\tmm\tHg\nSmoking\nDiabetes\tmellitus\nHypercholesterolemia\nObesity\nExcessive\talcohol\tintake\nEvidence\tof\tend\torgan\tdamage... | [
-0.050629522651433945,
-0.07707265019416809,
-0.00731219258159399,
0.009443448856472969,
-0.05181580409407616,
-0.020417125895619392,
0.06858910620212555,
0.09311383217573166,
-0.05347073823213577,
-0.0007704784511588514,
0.016016244888305664,
0.014152366667985916,
-0.024913912639021873,
-... |
Evidence\tof\tend\torgan\tdamage\nCardiac\nCardiac\tenlargement\nElectrocardiographic\tsigns\tof\tischemia\tor\tleft\tventricular\tstrain\nMyocardial\tinfarction\nHeart\tfailure\nEyes\nRetinal\texudates\tand\themorrhages\nPapilledema\nRenal\nImpaired\trenal\tfunction | [
-0.03660624101758003,
-0.0211909431964159,
0.015053479932248592,
-0.01585869863629341,
-0.01751878298819065,
0.04480433836579323,
0.0034962696954607964,
0.06054504215717316,
0.008457988500595093,
0.07715246081352234,
0.08923749625682831,
-0.03634919598698616,
-0.029926912859082222,
0.09454... |
Nervous\tsystem\nCerebrovascular\taccident\nFrom\tFisher\tND,\tWilliams\tGH:\tHypertensive\tvascular\tdisease.\tIn\tKasper\tDL,\tet\tal,\teditors:\t\nHarrison’s\nprinciples\tof\tinternal\tmedicine,\n\ted\t16,\tNew\tYork,\t2005,\tMcGraw-Hill.\nPathophysiology\nBlood\tpressure\n\tis\ta\tfunction\tof\tcardiac\toutput\tmul... | [
-0.013545681722462177,
-0.08602330088615417,
0.045527324080467224,
-0.014224478974938393,
-0.10634952783584595,
0.004983082413673401,
0.044926293194293976,
0.042316753417253494,
-0.03218807652592659,
0.06440418213605881,
0.045187775045633316,
0.011496608145534992,
0.01831684447824955,
0.03... |
the\tblood\tvessels\tto\tthe\tflow\tof\tblood).\tThus\n\tthe\tdiameter\tof\tthe\tblood\tvessel\tmarkedly\taffects\tblood\nflow.\tWhen\tthe\tdiameter\tis\tdecreased\t(as\tin\tatherosclerosis)\tresistance\tand\tblood\tpressure\tincrease.\nConversely,\twhen\tthe\tdiameter\tis\tincreased\t(as\twith\tvasodilator\tdrug\tther... | [
-0.013067898340523243,
-0.06983847171068192,
0.060116782784461975,
-0.02114066109061241,
-0.1342657059431076,
0.005791693460196257,
0.09507691115140915,
-0.011354616843163967,
0.022904610261321068,
0.05683433264493942,
0.09911227226257324,
-0.00864407978951931,
0.0658138170838356,
0.044548... |
and\tblood\tpressure\tis\tlowered.\nMany\tsystems\tmaintain\thomeostatic\tcontrol\tof\tblood\tpressure.\tThe\tmajor\tregulators\tare\tthe\tSNS\nfor\tshort-term\n\tcontrol\tand\tthe\tkidney\tfor\tlong-term\tcontrol.\tIn\tresponse\tto\ta\tfall\tin\tblood\tpressure,\nthe\tSNS\tsecretes\tnorepinephrine,\ta\tvasoconstrictor... | [
0.024011636152863503,
-0.022546589374542236,
0.05189951881766319,
-0.030101118609309196,
-0.11348842084407806,
0.020904889330267906,
0.054645001888275146,
0.04241158068180084,
-0.006402080412954092,
0.030433472245931625,
0.09433886408805847,
-0.07196322828531265,
0.010682428255677223,
0.02... |
increase\tperipheral\tresistance\tand\traise\tblood\tpressure.\tConditions\tthat\tresult\tin\toverstimulation\tof\nthe\tSNS\t(i.e.,\tcertain\tadrenal\tdisorders\tor\tsleep\tapnea)\tresult\tin\tincreased\tblood\tpressure.\tThe\nkidney\tregulates\n\tblood\tpressure\tby\tcontrolling\tthe\textracellular\tfluid\tvolume\tand... | [
0.011442127637565136,
-0.06465683877468109,
0.0352986603975296,
-0.020280107855796814,
-0.09264743328094482,
-0.004994010552763939,
0.12296649068593979,
-0.013657160103321075,
0.008878505788743496,
0.06471498310565948,
0.08719842880964279,
-0.03954138606786728,
0.05996791273355484,
0.01139... |
which\tactivates\tthe\t\nrenin-angiotensin\tsystem\t(RAS)\n\t(\nFig.\t32.8\n).\tAbnormal\tblood\tpressure\tis\nusually\tmultifactorial.\tIn\tmost\tcases\tof\thypertension,\tperipheral\tresistance\tincreases.\tThis\tresistance\nforces\tthe\tleft\tventricle\tof\tthe\theart\tto\tincrease\tits\teffort\tin\tpumping\tblood\t... | [
0.015220468863844872,
-0.04834212362766266,
0.02781340293586254,
-0.032289616763591766,
-0.06086951494216919,
0.01206777524203062,
0.06806560605764389,
0.026402710005640984,
0.03258206695318222,
0.08049054443836212,
0.08784965425729752,
-0.004545119125396013,
0.055542852729558945,
0.032677... |
time,\tLVH\tand\teventually\n\tHF\tcan\tdevelop.\nFIG.\t32.8\nRenin-angiotensin\tcascade.\nACE,\n\tAngiotensin-converting\tenzyme.\n\tSource:\t(Reprinted\twith\tpermission\tfrom\nFox\tSI:\t\nHuman\tphysiology\n,\ted\t6,\tNew\tYork,\t1999,\tMcGraw-Hill.)\nCommon\tgenetic\tvariants\tof\tthe\tRAS\tgene,\tincluding\tangiot... | [
-0.05447585880756378,
-0.06436583399772644,
0.019345229491591454,
-0.01953505352139473,
-0.04509471729397774,
0.01285804994404316,
0.024278748780488968,
0.08574724197387695,
0.01765693537890911,
0.029327502474188805,
0.08145511150360107,
-0.015890780836343765,
-0.028171436861157417,
0.0191... |
angiotensinogen,\thave\tshown\trelationships\twith\thypertension\t(\nHeidari\tet\tal,\t2017\n).\tAn\tincreased\nproduction\tof\tthese\tproteins\tmay\n\tincrease\tproduction\tof\tangiotensin\tII,\tthe\tprimary\tmediator\tof\tthe\nRAS,\tthus\tincreasing\tblood\tpressure.\tAngiotensin\tII\tmay\talso\ttrigger\tlow-grade\ti... | [
0.004851492587476969,
-0.03551589325070381,
0.03998628631234169,
0.009363527409732342,
-0.006462561432272196,
0.06100605055689812,
0.05877022445201874,
0.05220261216163635,
-0.0037215242628008127,
0.05549457669258118,
0.09869667887687683,
-0.020431999117136,
0.009100387804210186,
0.0346079... |
the\tblood\tvessel\twall,\ta\tcondition\tthat\tpredisposes\tto\thypertension\t(\nMcMaster\tet\tal,\t2015\n).\nHypertension\toften\toccurs\twith\tother\trisk\tfactors\tfor\tCVD,\tincluding\tvisceral\t(intraabdominal)\nobesity,\tinsulin\tresistance,\thigh\ttriglycerides,\n\tand\tlow\tHDL\tcholesterol\tlevels.\tThe\tcoexi... | [
-0.0319945402443409,
-0.05523815378546715,
0.018281806260347366,
-0.033256422728300095,
-0.07511942088603973,
-0.03369263932108879,
0.07519181072711945,
0.06664132326841354,
0.012071410194039345,
0.03260808065533638,
0.09802395850419998,
-0.01773741841316223,
0.03694472461938858,
0.0366004... |
and\tlow\tHDL\tcholesterol\tlevels.\tThe\tcoexistence\tof\nthree\tor\tmore\tof\tthese\trisk\tfactors\tleads\tto\tmetabolic\tsyndrome.\tIt\tis\tunclear\twhether\tone\tor\tmore\tof\nthese\trisk\tfactors\tprecede\tthe\tothers\tor\twhether\tthey\toccur\tsimultaneously.\tAccumulation\tof\tvisceral | [
-0.0009312183829024434,
-0.053504958748817444,
0.012613733299076557,
-0.03998276963829994,
-0.1358531266450882,
0.0009231592412106693,
0.03533720597624779,
-0.010135339573025703,
0.010114304721355438,
0.04139917343854904,
0.10951100289821625,
-0.03666897490620613,
0.05130419135093689,
0.03... |
fat\tsynthesizes\tincreased\tamounts\tof\tangiotensinogen,\twhich\tactivates\tthe\tRAS\tand\tincreases\tblood\npressure\t(\nZhou\tet\tal,\t2012\n).\tAlso,\tangiotensin\n\tII,\tthe\tprimary\tmediator\tof\tthe\tRAS,\tpromotes\tthe\ndevelopment\tof\tlarge\tdysfunctional\tadipocytes,\twhich\tproduce\tincreased\tamounts\tof... | [
-0.031542595475912094,
-0.0904553160071373,
0.008360129781067371,
0.015545979142189026,
-0.0552525632083416,
0.04854901134967804,
0.08233426511287689,
0.06621085107326508,
-0.02935161255300045,
0.08472584933042526,
0.13305576145648956,
-0.05685828998684883,
-0.0056212302297353745,
0.056268... |
reduced\tquantities\tof\tadiponectin.\tHigher\tlevels\tof\tleptin\tand\tlower\tamounts\tof\tcirculating\nadiponectin\tactivate\tthe\tSNS,\ta\tkey\tcomponent\tof\tthe\thypertensive\tresponse\t(\nDeMarco\tet\tal,\t2014\n). | [
0.005574167240411043,
-0.017447926104068756,
0.012516492046415806,
-0.024578487500548363,
-0.09299571067094803,
0.02545461431145668,
0.07399730384349823,
0.054533474147319794,
0.02459890767931938,
0.0506366491317749,
0.11041992157697678,
0.029868312180042267,
0.013926721177995205,
0.052452... |
Primary\tprevention\nPositive\tchanges\tin\thypertension\tawareness,\n\ttreatment,\tand\tcontrol\thave\toccurred\tduring\tthe\tlast\nseveral\tyears.\tBased\ton\tanalysis\tof\tNational\tHealth\tand\tNutrition\tExamination\tSurvey\t(NHANES)\ndata\tfrom\t2011\tto\t2014,\t84.1%\tof\tpeople\twith\thypertension\tare\taware\t... | [
-0.008898895233869553,
-0.00596641143783927,
0.053589049726724625,
-0.020514529198408127,
-0.0384293869137764,
0.010461467318236828,
0.08185353130102158,
0.02041878178715706,
0.003837315831333399,
0.03502853959798813,
0.09798066318035126,
-0.042588721960783005,
0.04232698306441307,
-0.0082... |
Benjamin\tet\nal,\t2018\n),\tup\tfrom\t81%\tin\t2007\tto\t2010.\tAlthough\tcurrent\thypertension\ttreatment\tand\tcontrol\trates\nhave\tincreased\tfrom\t48.4%\tto\t53.3%,\tduring\tthis\tsame\n\ttime\tperiod,\tadditional\tefforts\tare\tneeded\tto\nmeet\tthe\t\nHealthy\tPeople\t2020\n\tobjective\tof\t61.2%.\tIn\t2015\two... | [
-0.021301427856087685,
0.00993102416396141,
0.04821746051311493,
-0.0471939891576767,
-0.10196153074502945,
0.04275134950876236,
0.07187962532043457,
0.03236386179924011,
-0.05537767708301544,
0.06014766916632652,
0.12062417715787888,
-0.065178781747818,
0.043474581092596054,
-0.0115772746... |
objective\tof\t61.2%.\tIn\t2015\twomen,\tyounger\tadults\t(aged\t18\tto\t39\nyears),\tand\tHispanic\tindividuals\thad\tlower\trates\tof\tblood\tpressure\tcontrol\tcompared\twith\tmen,\nyounger\tindividuals,\tand\tnon-Hispanic\twhites.\tImproving\thypertension\ttreatment\tthrough\ttargeted\nintervention\tprograms\tshoul... | [
0.03702062740921974,
0.008593806065618992,
0.0493113175034523,
0.013352647423744202,
-0.08024948835372925,
0.038261789828538895,
0.07358229160308838,
-0.03162282705307007,
-0.06783460080623627,
0.05517588183283806,
0.11762651056051254,
-0.06840173900127411,
0.00912497565150261,
0.013518996... |
intervention\tprograms\tshould\thave\ta\tpositive\teffect\ton\tCVD\toutcomes.\n\tBlood\tpressure\ttreatment\nguidelines\thighlight\tthe\timportance\tof\tevaluating\tpatients\tfor\tthe\tpresence\tof\tmultiple\tCVD\trisk\nfactors\tand\tindividualizing\tlifestyle\tmodification\tand\tdrug\ttherapies\taccordingly. | [
-0.01357602421194315,
0.0035210063215345144,
0.06512930244207382,
0.008889742195606232,
-0.12069178372621536,
0.022522032260894775,
0.0634194016456604,
0.054205868393182755,
-0.03454356640577316,
-0.020929791033267975,
0.0650620386004448,
-0.007274507079273462,
0.030125079676508904,
0.0330... |
Changing\tlifestyle\tfactors\thave\tdocumented\tefficacy\tin\tthe\tprimary\tprevention\tand\tcontrol\tof\nhypertension.\tThese\tfactors\twere\tsystematically\treviewed\tand\tcategorized\tby\tthe\tAcademy\tof\nNutrition\n\tand\tDietetics\t(AND)\tin\t2015\t(\nLennon\tet\tal,\t2017\n)\tand\tmore\trecently\tby\tthe\tACC\ta... | [
0.0033001056872308254,
-0.0013194282073527575,
0.05747679993510246,
-0.059078097343444824,
-0.06345868110656738,
0.036162421107292175,
0.07485729455947876,
-0.028322089463472366,
0.0026945031713694334,
0.0641971230506897,
0.0688246637582779,
-0.05091756209731102,
0.040945250540971756,
0.01... |
)\tand\tmore\trecently\tby\tthe\tACC\tand\tAHA\nin\t2018\t(\nWhelton\tet\tal,\t2018\n).\tThese\tguidelines\tmade\ta\tstrong\trecommendation\t(i.e.,\thigh\nbenefit/risk\tratio\twith\tsupporting\tevidence)\tfor\treducing\tintake\tof\tdietary\tsodium\tin\tadults\twith\nelevated\tblood\tpressure\tand\thypertension\tand\tfo... | [
0.002000197535380721,
-0.025445686653256416,
0.03490055724978447,
0.00245422450825572,
-0.045526061207056046,
-0.009129084646701813,
0.11110250651836395,
0.02620014362037182,
-0.041168466210365295,
0.019032755866646767,
0.07720500230789185,
-0.014864768832921982,
0.06276702880859375,
0.004... |
or\thypertension\twho\tare\n\toverweight\tor\tobese.\tA\tstrong\trecommendation\twas\talso\tmade\tfor\ta\theart-\nhealthy\tdietary\tpattern\tsuch\tas\tthe\tDASH\tdiet\trich\tin\tfruits,\tvegetables,\twhole\tgrains,\tand\tlow-fat\ndairy\tto\tlower\tblood\tpressure.\tCombining\ta\tlow-sodium\tDASH\tdiet\twith\tweight\tre... | [
-0.015335258096456528,
-0.03272303193807602,
0.047886643558740616,
0.004898892715573311,
-0.04851783812046051,
0.00890620518475771,
0.0722600668668747,
0.004834091290831566,
-0.05218081548810005,
0.026073332875967026,
0.0839434340596199,
-0.028532955795526505,
0.03917335718870163,
-0.00459... |
recommended\tas\tthe\tmost\tefficacious\tapproach\tto\tsubstantially\tlowering\tblood\tpressure\tin\tadults\tat\nhigh\tCVD\trisk.\tAdditional\tstrong\trecommendations\n\tfrom\tboth\tthe\tACC/AHA\tand\tthe\tAND\twere\tmade\nfor\tincreasing\tphysical\tactivity\twith\ta\tstructured\texercise\tprogram\tand\tfor\tmoderating... | [
0.00962895154953003,
-0.08039519190788269,
0.08467591553926468,
-0.014870977029204369,
-0.07732129096984863,
-0.017031017690896988,
0.10829170048236847,
0.0360480435192585,
-0.05611051246523857,
0.022922683507204056,
0.05167796090245247,
-0.016910646110773087,
0.031631458550691605,
0.03153... |
consumption,\tparticularly\tamong\theavy\tdrinkers.\tThe\tACC/AHA\talso\tincluded\ta\tstrong\nrecommendation\tfor\tsupplementation\twith\tpotassium\tto\tlower\tblood\tpressure.\tIncreased\tpotassium\nintake\tshould\tpreferably\tbe\tin\tthe\tform\tof\tdiet\tmodification\tand\tmay\tbe\tcontraindicated\n\tfor\tsome | [
0.052559416741132736,
-0.0030593450646847486,
0.06859015673398972,
0.019107738509774208,
-0.07094331085681915,
0.02254146710038185,
0.13378852605819702,
-0.01013107318431139,
-0.015932779759168625,
0.06348903477191925,
0.10042288154363632,
-0.05749453231692314,
0.045283958315849304,
0.0069... |
for\tsome\npatients\twith\tCKD.\tA\tsummary\tof\trecommendations\tand\tratings\tfrom\tthe\tACC/AHA\tand\tthe\tAND\tcan\nbe\tfound\tin\t\nTable\t32.3\n.\nTABLE\t32.3\nRecommendations\ton\tBlood\tPressure\tin\tHypertensive\tAdults\tfrom\tEvidence\tAnalysis\tLibrary\t(2015)\tand\nAmerican\tCollege\tof\tCardiology/American... | [
-0.01622859016060829,
-0.04415799304842949,
0.015293216332793236,
0.0008017208310775459,
-0.045583292841911316,
0.028832830488681793,
0.07028964161872864,
0.004043832421302795,
-0.013437895104289055,
0.027500446885824203,
0.06077851727604866,
-0.043553709983825684,
0.0034433617256581783,
0... |
Food\tor\nNutrient\nEAL\tRecommendation\nRating\nACC/AHA\tRecommendation\nRating\nSodium\nThe\tRDN\tshould\tcounsel\non\treducing\tsodium\nintake\tfor\tblood\npressure\treduction\tin\nadults\twith\tHTN.\nLowering\n\tdietary\nsodium\tintake\tto\n1500-2000\tmg/day\nreduced\tSBP\tand\tDBP\nup\tto\t12\tand\t6\tmm\nHg,\tres... | [
-0.03445965796709061,
-0.06276354938745499,
0.04847168177366257,
0.041531842201948166,
-0.072986900806427,
-0.03506404533982277,
0.1136116236448288,
0.005063927266746759,
-0.09306947886943817,
0.005142554175108671,
0.08972828090190887,
-0.06204141676425934,
0.021893346682190895,
-0.0061403... |
Strong\nLower\tsodium\tintake\nConsume\tno\tmore\tthan\t2400\nmg\tof\tsodium/day;\tfurther\nreduction\tof\tsodium\tto\t1500\nmg/day\tis\tdesirable\tbecause\nit\tis\tassociated\twith\teven\ngreater\treduction\tin\tblood\npressure;\treduce\tintake\tby\tat\nleast\t1000\tmg/day\tbecause\nthat\twill\tlower\tblood\npressure,... | [
-0.011600927449762821,
-0.041145384311676025,
0.061059657484292984,
0.026925375685095787,
-0.09725573658943176,
-0.03953935578465462,
0.09045281261205673,
0.020981663838028908,
-0.07875188440084457,
0.02986280992627144,
0.08951365202665329,
-0.06596692651510239,
0.02943277359008789,
0.0262... |
daily\n\tsodium\tintake\tis\tnot\nachieved.\nStrong\nModerate\nDietary\npatterns\nemphasizing\nfruits\tand\nvegetables\nThe\tRDN\tshould\tcounsel\non\ta\tDASH\tdietary\npattern\tplus\treduced\nsodium\tintake\tfor\nblood\tpressure\nreduction.\nConsensus\nConsume\ta\tdietary\tpattern\tthat\nemphasizes\tintake\tof\tvegeta... | [
-0.005893982481211424,
-0.05262068286538124,
0.05472957342863083,
0.036423563957214355,
-0.02922607958316803,
-0.006149403750896454,
0.11100596934556961,
-0.00021182242198847234,
-0.07502168416976929,
0.035452742129564285,
0.1071406826376915,
-0.04249877855181694,
0.03749818354845047,
-0.0... |
fruits,\tand\twhole\tgrains;\nincludes\tlow-fat\tdairy\tproducts,\npoultry,\tfish,\tlegumes,\nnontropical\tvegetable\toils\tand\nnuts;\tand\tlimits\tintake\tof\tsweets,\nsugar-sweetened\tbeverages,\tand\nred\tmeat;\tadapt\tthe\tpattern\tto\nappropriate\tcalorie\nrequirements;\tachieve\tthis\npattern\tby\tfollowing\tpla... | [
0.027836188673973083,
-0.016812071204185486,
0.03927953913807869,
0.011309354566037655,
-0.057191163301467896,
0.04740394279360771,
0.08969731628894806,
-0.0385778471827507,
-0.017248211428523064,
0.06896521151065826,
0.18015001714229584,
-0.04646192118525505,
0.009372690692543983,
-0.0509... |
as\tDASH,\tUSDA\tfood\tpattern,\tor\nthe\tAHA\tDiet;\tcombine\tthe\nDASH\tdietary\tpattern\twith\tlower\nsodium\tintake.\nStrong\nFruits\tand\nvegetables\nFruits\tand\tvegetables\nshould\tbe\nrecommended\tat\ta\nlevel\tof\t5\tto\t10\nservings\tper\tday\tfor\nsignificant\tblood\npressure\treduction.\nStrong\nNot\nevalua... | [
0.005735802464187145,
-0.04819193482398987,
0.04427999258041382,
-0.01648237369954586,
-0.056664131581783295,
0.00979405827820301,
0.09548194706439972,
-0.013835436664521694,
-0.047960247844457626,
0.06604105234146118,
0.08788985759019852,
-0.0471654050052166,
0.02960100769996643,
0.025963... |
Weight\nmanagement\nOptimal\tbody\tweight\nshould\tbe\tachieved\nStrong\nCounsel\toverweight\tand\tobese\nadults\twith\thigh\tblood\tpressure\nStrong | [
-0.002015944104641676,
-0.016870347782969475,
0.047790609300136566,
0.047136735171079636,
-0.09030729532241821,
-0.042576879262924194,
0.10174381732940674,
0.008687206543982029,
-0.11041837930679321,
0.04346177354454994,
0.03978924825787544,
-0.059399157762527466,
-0.009531399235129356,
0.... |
and\tmaintained\t(BMI\n18.5-24.9)\tto\treduce\nblood\tpressure.\nthat\tlifestyle\tchanges\tthat\nproduce\teven\tmodest,\tsustained\nweight\tloss\tof\t3%\tto\t5%\tproduce\nclinically\tmeaningful\tbenefits\n(e.g.,\treduce\tTG,\tblood\tsugar,\n\tHb\nA1C);\t>5%\twill\treduce\tblood\npressure\tand\treduce\tthe\tneed\nfor\tm... | [
-0.016180753707885742,
-0.07519609481096268,
0.035089243203401566,
0.026218267157673836,
-0.10173224657773972,
-0.01958722621202469,
0.11210913956165314,
0.03853767365217209,
-0.05917903408408165,
0.02373499795794487,
0.08511653542518616,
-0.07715547829866409,
-0.004204952158033848,
0.0341... |
for\tmedications\tto\tcontrol\tblood\npressure.\n*\nPhysical\nactivity\nIndividuals\tshould\tbe\nencouraged\tto\tengage\nin\taerobic\tphysical\nactivity\tfor\tat\tleast\t30\nminutes\tper\tday\ton\nmost\tdays\tof\tthe\nweek,\tbecause\tit\nreduces\tSBP.\nConsensus\nAdvise\tadults\tto\tengage\tin\taerobic\nphysical\tactiv... | [
0.028380004689097404,
-0.07301229238510132,
0.051417265087366104,
-0.012067969888448715,
-0.11054051667451859,
0.0009596553863957524,
0.10132259875535965,
-0.0001864527876023203,
-0.06258872896432877,
0.05213183909654617,
0.07755916565656662,
-0.0665636956691742,
0.01561572216451168,
0.062... |
physical\tactivity\tto\tlower\tblood\npressure:\tthree\tto\tfour\tsessions\na\tweek,\tlasting\ton\taverage\t40\nminutes\tper\tsession,\tand\ninvolving\tmoderate-to-vigorous-\nintensity\tphysical\tactivity.\nModerate\nAlcohol\nFor\tindividuals\twho\tcan\nsafely\tconsume\nalcohol,\tconsumption\nshould\tbe\tlimited\tto\nn... | [
0.019221941009163857,
-0.08143940567970276,
0.07746989279985428,
-0.0000650512520223856,
-0.11727382242679596,
-0.006239932496100664,
0.10343314707279205,
-0.012414113618433475,
-0.04899517819285393,
0.04247843474149704,
0.07481187582015991,
-0.06833121925592422,
0.02581907995045185,
0.056... |
no\tmore\tthan\ttwo\ndrinks\t(24\toz\tbeer,\t10\noz\twine,\tor\t3\toz\tof\t80-\nproof\tliquor)\tper\tday\nin\tmost\tmen\tand\tto\tno\nmore\tthan\tone\tdrink\nper\tday\tin\twomen.\nConsensus\nNot\nevaluated\nPotassium\nStudies\tsupport\ta\nmodest\trelationship\nbetween\tincreasing\nintake\tof\tpotassium\nand\ta\tlower\t... | [
-0.029261769726872444,
-0.01997421309351921,
0.043744705617427826,
-0.0351206474006176,
-0.10899335145950317,
0.003159796819090843,
0.050022877752780914,
-0.03888581320643425,
-0.04722097888588905,
0.08020404726266861,
0.11353188753128052,
-0.05044473707675934,
0.05247630178928375,
-0.0009... |
lowered\tblood\npressure.\nFair\nInsufficient\tevidence\nLow\nCalcium\nThe\teffect\tof\tincreasing\ncalcium\tintake\twith\nlowered\tblood\npressure\tis\tunclear;\nalthough\tsome\nresearch\tindicates\nminimal\tbenefit.\nFair\nNot\nevaluated\nMagnesium\nThe\teffect\tof\tincreasing\nmagnesium\tintake\nwith\tlowered\n\tblo... | [
0.06948477029800415,
-0.045724548399448395,
0.06783178448677063,
0.015094024129211903,
-0.0609436072409153,
0.015834463760256767,
0.05118568614125252,
0.04368908330798149,
0.002703981939703226,
0.10725846141576767,
0.07939697057008743,
-0.027249325066804886,
0.04651258513331413,
0.06911268... |
blood\npressure\tis\tunknown;\nalthough\tsome\nresearch\tindicates\nminimal\tbenefit.\nFair\nNot\nevaluated\nOmega-3\tfatty\nacids\nStudies\tinvestigating\nincreased\nconsumption\tof\nomega-3\tfatty\tacids\nhave\tnot\ndemonstrated\ta\nbeneficial\teffect\ton\nblood\tpressure.\nFair\nNot\nevaluated\nACC\n,\tAmerican\tCol... | [
-0.004926059395074844,
-0.0459546260535717,
0.06523976475000381,
-0.02543703466653824,
-0.1250878870487213,
0.007110188715159893,
0.02329174242913723,
-0.0635642260313034,
0.005556863732635975,
0.07621823996305466,
0.09602870792150497,
-0.1079435870051384,
-0.02743135578930378,
0.011999450... |
AHA\n,\tAmerican\tHeart\tAssociation;\t\nBMI\n,\tbody\tmass\tindex;\t\nDASH\n,\tDietary\tApproaches\tto\tStop\n\tHypertension;\nDBP\n,\tdiastolic\tblood\tpressure;\t\nHb\tA1C\n,\themoglobin\tA1C;\t\nHTN\n,\thypertension;\t\nRDN\n,\tregistered\tdietitian\tnutritionist;\t\nSBP\n,\tsystolic\tblood\tpressure;\nTG\n,\ttrigl... | [
-0.004477407317608595,
-0.07894213497638702,
-0.003839086275547743,
-0.04688087850809097,
-0.09976047277450562,
0.008261024951934814,
0.07852158695459366,
0.01876811496913433,
-0.03559708222746849,
0.0745614543557167,
0.1221565380692482,
-0.026818815618753433,
0.036906711757183075,
-0.0038... |
TG\n,\ttriglyceride;\t\nUSDA\n,\tU.S.\tDepartment\tof\tAgriculture.\nRecommendations\tlisted\tare\tfor\tthose\trated\tby\tthe\tAcademy\tof\tNutrition\tand\tDietetics\tand\tthe\tAmerican\tAcademy\tof\tCardiology\t(ACC)/American\nHeart\tAssociation\t(AHA)\tas\tstrong,\tfair/moderate,\n\tand\tconsensus;\tfor\tthose\twith\... | [
0.013074862770736217,
-0.0339851938188076,
0.0461239255964756,
-0.01748066209256649,
-0.08405982702970505,
0.0014327086973935366,
0.09028834849596024,
-0.041003983467817307,
-0.0007916617905721068,
0.047745440155267715,
0.11182272434234619,
-0.05711480230093002,
0.021381249651312828,
0.000... |
Analysis\tLibrary\tfor\tHypertension\t(2009)\t\nhttp://www.adaevidencelibrary.com/topic.cfm?cat=3259\n\tor\tthe\tACC/AHA\tdata\tsupplement\tat\nhttp://circ.ahajournals.org/lookup/suppl/doi:10.1161/01.cir.0000437740.48606.d1/-DC1\n*\nWeight\tmanagement\tguidelines\tare\tfrom\tJensen\tMD,\tet\tal:\t2013\tAHA/ACC/TOS\tgui... | [
-0.09571680426597595,
0.02125939354300499,
-0.05344896391034126,
-0.000799933506641537,
-0.020759839564561844,
0.01022970862686634,
-0.04190906882286072,
0.021562933921813965,
-0.012999526225030422,
0.033852048218250275,
0.08011315017938614,
0.049853987991809845,
-0.0017603220185264945,
-0... |
the\tmanagement\tof\toverweight\tand\tobesity\tin\tadults:\na\treport\tof\tthe\tAmerican\tCollege\tof\tCardiology/American\tHeart\tAssociation\tTask\tForce\ton\tPractice\tGuidelines,\tand\tthe\tObesity\tSociety,\tJ\tAm\tColl\nCardiol\t63:2985,\t2014.\nFats\nSystematic\treviews\tof\tRCTs\tthat\texamined\tthe\teffects\to... | [
0.010844896547496319,
-0.08639294654130936,
0.042672645300626755,
-0.013774411752820015,
-0.13493512570858002,
-0.006091642193496227,
0.018233075737953186,
-0.008279003202915192,
-0.0052558621391654015,
0.02318393625319004,
0.06308266520500183,
-0.044229503720998764,
0.010965473018586636,
... |
with\tanother\thave\tgenerally\tshown\tno\tor\tonly\ta\tsmall\teffect\ton\tblood\n\tpressure\t(\nAl-Khudairy\tet\tal,\n2015\n;\t\nMaki\tet\tal,\t2018\n).\tSupplementation\twith\tn-3\tPUFAs\t(EPA\t+\tDHA)\tin\tdoses\thigher\tthan\t2\tg/day\nshowed\tmodest\treductions\tin\tSBP\tand\tDBP,\tespecially\tin\tuntreated\thyper... | [
-0.052288491278886795,
0.019820092245936394,
0.06595277786254883,
-0.014826261438429356,
-0.0966404527425766,
-0.012943467125296593,
0.02770150825381279,
0.015869535505771637,
-0.0297390129417181,
0.04045941308140755,
0.1131533533334732,
-0.0776536837220192,
0.0015605947701260448,
0.023465... |
Protein\nEvidence\tfrom\tobservational\tstudies\tand\tRCTs\tsuggests\treplacement\tof\tprotein\tfor\tfat\tor\ncarbohydrate\tin\tan\tisocaloric\tdiet\tresults\tin\tlowered\tblood\tpressure\n\t(\nBazzano\tet\tal,\t2013\n).\tProtein\nsupplementation\tin\tdoses\tof\t60\tg/day\treduced\tSBP\tby\t4.9\tmm\tHg\tand\tDBP\tby\t2... | [
-0.021571701392531395,
-0.0809192955493927,
0.03938968479633331,
-0.010517352260649204,
-0.02861379086971283,
0.043112266808748245,
0.10732577741146088,
0.05905735865235329,
-0.035454265773296356,
0.02434166707098484,
0.07460857182741165,
-0.015798017382621765,
-0.0001402187772328034,
0.04... |
with\t60\tg/day\tof\tcarbohydrate\tin\toverweight\tindividuals\twith\televated\tblood\tpressure\tand\tuntreated\nstage\t1\thypertension\t(\nTeunissen-Beekman\tand\tvan\tBaak,\t2013\n).\nDietary\tpatterns\temphasizing\tfruits\tand\tvegetables\nSeveral\tdietary\tpatterns\thave\tbeen\tshown\tto\tlower\tblood\tpressure.\n\... | [
-0.014132863841950893,
0.0018049163045361638,
0.04491989314556122,
-0.0073348223231732845,
-0.07999655604362488,
0.023443400859832764,
0.1302478313446045,
0.01966089755296707,
-0.04393642395734787,
0.023508837446570396,
0.11156193912029266,
-0.05343445762991905,
0.014701453037559986,
0.018... |
Plant-based\tdietary\tpatterns\thave\nbeen\tassociated\twith\tlower\tSBP\tin\tobservational\tstudies\tand\tclinical\ttrials\t(\nAlexander\tet\tal,\t2017\n).\nAverage\tSBP\treductions\tof\t5\tto\t6\tmm\tHg\thave\tbeen\treported.\tSpecifically,\tthe\t\nDietary\tApproaches\nto\tStop\tHypertension\t(DASH)\n\tcontrolled\tfe... | [
-0.01282419916242361,
-0.06551912426948547,
0.05511578917503357,
-0.04553265497088432,
-0.077159084379673,
0.022463586181402206,
0.05441432073712349,
0.012815076857805252,
-0.004834105726331472,
0.08001730591058731,
0.13360247015953064,
-0.01202313881367445,
0.025446588173508644,
0.0016242... |
controlled\tfeeding\tstudy\tshowed\tthat\ta\tdietary\tpattern\temphasizing\nfruits,\tvegetables,\tlow-fat\tdairy\tproducts,\twhole\tgrains,\tlean\tmeats,\n\tand\tnuts\tsignificantly\tdecreased\nSBP\tin\thypertensive\tand\tnormotensive\tadults.\tThe\tDASH\tdiet\t(see\t\nAppendix\t17\n)\twas\tfound\tto\tbe | [
0.020585615187883377,
-0.058207087218761444,
0.04485446959733963,
-0.00784685555845499,
-0.08225060254335403,
0.018804345279932022,
0.11734228581190109,
-0.0013348732609301805,
-0.023762978613376617,
0.07425493001937866,
0.14270365238189697,
-0.026735495775938034,
0.040816664695739746,
-0.... |
Appendix\t17\n)\twas\tfound\tto\tbe\nmore\teffective\tthan\tjust\tadding\tfruits\tand\tvegetables\tto\ta\tlow-fat\tdietary\tpattern\tand\twas\tequally\neffective\tin\tmen\tand\twomen\tof\tdiverse\tracial\tand\tethnic\tbackgrounds\t(\nAppel\tet\tal,\t2006\n).\tThis\ndietary\tpattern\tserves\tas\tthe\tcore\tfor\tthe\tACC... | [
0.04957820475101471,
-0.0007097970228642225,
0.08017390221357346,
-0.056118059903383255,
-0.07538150995969772,
-0.021104363724589348,
0.0632888451218605,
-0.013225609436631203,
-0.018204839900135994,
0.056849706918001175,
0.11034122854471207,
0.010795560665428638,
0.0468527153134346,
0.018... |
lowering\tblood\npressure\t(\nWhelton\tet\tal,\t2018\n).\tAlthough\tthe\tDASH\tdiet\tis\tsafe\tand\tcurrently\tadvocated\tfor\npreventing\tand\ttreating\thypertension,\tthe\tdiet\tis\thigh\tin\tpotassium,\tphosphorus,\tand\tprotein,\ndepending\ton\thow\tit\tis\tplanned.\tFor\tthis\treason\tthe\tDASH\tdiet\tmay\tnot\tbe... | [
0.025422681123018265,
-0.00517366174608469,
0.09692654013633728,
-0.03614400327205658,
-0.05806940421462059,
-0.000994137255474925,
0.07659794390201569,
0.05437786132097244,
0.019971992820501328,
0.09066624194383621,
0.0853046253323555,
0.039666302502155304,
0.029173118993639946,
0.0334977... |
with\tend-stage\trenal\tdisease\twith\thigh-normal\tor\televated\tserum\tpotassium\tand\tphosphorus\tlevels\n(\nTyson\tet\tal,\t2012\n).\nSeveral\tversions\tof\tthe\tDASH\tdiet\thave\tbeen\texamined\tin\tregard\tto\tblood\tpressure–lowering\npotential.\tThe\tOmniHeart\ttrial\tcompared\tthe\toriginal\tDASH\tdiet\tto\ta\... | [
0.01623009704053402,
-0.08759315311908722,
0.044189926236867905,
-0.05570555478334427,
-0.16716887056827545,
-0.026123404502868652,
0.04319153353571892,
0.054590705782175064,
-0.010809223167598248,
0.0568927563726902,
0.08719649165868759,
0.010343963280320168,
0.02759309858083725,
0.057042... |
DASH\tdiet\t(25%\tof\tenergy\tfrom\tprotein,\tapproximately\thalf\tfrom\tplant\tsources),\tand\ta\tDASH\tdiet\nhigh\tin\tunsaturated\tfat\t(31%\tof\tcalories\tfrom\tunsaturated\tfat,\tmostly\tmonounsaturated).\tAlthough\neach\tdiet\tlowered\n\tSBP,\tsubstituting\tsome\tof\tthe\tcarbohydrate\t(approximately\t10%\tof\tto... | [
-0.015193980187177658,
-0.057970255613327026,
0.04459580034017563,
-0.03626938536763191,
-0.06930196285247803,
-0.03804066404700279,
0.09904070198535919,
0.06349162757396698,
-0.011807412840425968,
0.0037264523562043905,
0.08128755539655685,
-0.021916745230555534,
0.021058786660432816,
0.0... |
in\tthe\tDASH\tdiet\twith\teither\tprotein\tor\tmonounsaturated\tfat\tachieved\tthe\tbest\treduction\tin\tblood\npressure\tand\tblood\tcholesterol\t(\nMiller\tet\tal,\t2006\n).\tThis\tcould\tbe\tachieved\tby\tsubstituting\tnuts\tfor\nsome\tof\tthe\tfruit,\tbread,\tor\tcereal\tservings.\nBecause\tmany\thypertensive\tpat... | [
-0.007059694267809391,
-0.039750728756189346,
0.039824895560741425,
-0.02315506897866726,
-0.10418582707643509,
0.005558723583817482,
0.0632510557770729,
0.03282991051673889,
0.01832662895321846,
0.01598677970468998,
0.1170128658413887,
-0.0006582381320185959,
0.047454074025154114,
0.01903... |
of\tthe\tDASH\tdiet\talso\nhave\tbeen\ttested\tfor\tefficacy\tin\tpromoting\tweight\tloss\tand\tblood\tpressure\treduction.\tA\thypocaloric\nDASH\tdiet\tversus\ta\tlow-calorie,\tlow-fat\tdiet\tproduced\ta\tgreater\treduction\tin\tSBP\tand\tDBP.\tMore\nrecently,\tthe\tENCORE\tstudy\tshowed\tthat\tthe\taddition\tof\texer... | [
0.01773311384022236,
-0.05087224394083023,
0.031492073088884354,
0.021466286852955818,
-0.05992288887500763,
0.019538622349500656,
0.08511210978031158,
0.005830960348248482,
-0.01587936468422413,
0.06108511611819267,
0.05815424397587776,
-0.04100089520215988,
0.020473646000027657,
-0.00893... |
resulted\tin\tgreater\tblood\tpressure\treductions,\tgreater\timprovements\tin\tvascular\tfunction,\n\tand\nreduction\tin\tleft\tventricular\tmass\tcompared\twith\tthe\tDASH\tdiet\talone\t(\nLee\tet\tal,\t2018\n).\nThe\tMeD\tdietary\tpattern\thas\tmany\tsimilarities\tto\tthe\tDASH\tdiet\tbut\tis\tgenerally\thigher\tin\... | [
-0.008452757261693478,
-0.028441770002245903,
0.07897000759840012,
-0.06626297533512115,
-0.1233052909374237,
-0.022039521485567093,
0.09490081667900085,
0.05376935750246048,
-0.03645765036344528,
0.05831633880734444,
0.0860859677195549,
-0.04093781113624573,
-0.011677204631268978,
0.04199... |
primarily\tMUFA\tfrom\tolive\toil,\tnuts,\tand\tseeds.\tA\ttraditional\tMeD\tdiet\talso\tcontains\tfatty\tfish\trich\tin\nomega-3\tfatty\tacids.\tA\tsystematic\treview\tof\tthe\tMeD\tdiet\tand\tCVD\trisk\tfactors,\tfound\tthat\talthough\nlimited,\n\tevidence\tfrom\tRCTs\twas\tsuggestive\tof\ta\tblood\tpressure–lowering... | [
-0.018894752487540245,
-0.048247598111629486,
0.03138497471809387,
-0.04486652836203575,
-0.07885360717773438,
-0.012754686176776886,
0.07191536575555801,
0.04234309121966362,
-0.004516283515840769,
0.037319984287023544,
0.08859717845916748,
-0.04040105268359184,
0.05742621049284935,
0.004... |
pattern\tin\tadults\twith\thypertension\t(\nRees\tet\tal,\t2013\n).\tAccording\tto\tthe\tACC/AHA,\tmore\tstudies\ton\ndiverse\tpopulations\tare\twarranted\tbefore\trecommendations\tcan\tbe\tmade\trelated\tto\tthe\tMeD\tdiet\tfor\nuse\tin\tblood\tpressure\tmanagement\t(\nWhelton\tet\tal,\t2018\n).\nWeight\treduction\nTh... | [
-0.006532960571348667,
-0.026898536831140518,
0.06427762657403946,
-0.07191131263971329,
-0.09584754705429077,
0.002123225247487426,
0.04116884991526604,
-0.020843351259827614,
0.006713027134537697,
0.07834906131029129,
0.10151398926973343,
-0.06098521873354912,
0.02707752212882042,
0.0164... |
).\nWeight\treduction\nThere\tis\ta\tstrong\tassociation\tbetween\n\tBMI\tand\thypertension\tamong\tmen\tand\twomen\tin\tall\trace\tor\nethnic\tgroups\tand\tin\tmost\tage\tgroups.\tIt\tis\testimated\tthat\tat\tleast\t75%\tof\tthe\tincidence\tof\nhypertension\tis\trelated\tdirectly\tto\tobesity\t(\nBenjamin\tet\tal,\t20... | [
0.027516745030879974,
-0.04057883471250534,
0.05934029817581177,
-0.019398821517825127,
-0.08780976384878159,
-0.0012766964500769973,
0.10357672721147537,
0.0021231912542134523,
-0.029764484614133835,
0.08077473938465118,
0.12171433120965958,
-0.06981434673070908,
0.011788121424615383,
0.0... |
Benjamin\tet\tal,\t2018\n).\tWeight\tgain\tduring\tadult\tlife\tis\nresponsible\tfor\tmuch\tof\tthe\trise\tin\tblood\tpressure\tseen\twith\taging.\nSome\tof\tthe\tphysiologic\tchanges\tproposed\tto\texplain\tthe\trelationship\tbetween\texcess\n\tbody\tfat\tand\nblood\tpressure\tare\toveractivation\tof\tthe\tSNS\tand\tR... | [
-0.022061560302972794,
-0.042887985706329346,
0.055472858250141144,
-0.013896570540964603,
-0.08215642720460892,
0.003524323459714651,
0.12857648730278015,
0.02111034281551838,
-0.022038286551833153,
0.029398612678050995,
0.0876237228512764,
-0.0440051443874836,
0.033690378069877625,
0.025... |
Hall\tet\tal,\t2015\n).\nVisceral\tfat\tin\tparticular\tpromotes\tvascular\tinflammation\tby\tinducing\tcytokine\trelease,\nproinflammatory\ttranscription\tfactors,\tand\tadhesion\tmolecules\t(\nHall\tet\tal,\t2015\n).\tLow-grade\ninflammation\toccurs\tin\tthe\tvasculature\tof\tindividuals\twith\televated\tblood\tpress... | [
-0.009915193542838097,
-0.10546436905860901,
0.06607358157634735,
-0.062322650104761124,
-0.11874653398990631,
-0.01103584561496973,
0.10163884609937668,
0.04284564405679703,
-0.01157302875071764,
0.07055767625570297,
0.07683879137039185,
-0.04649413377046585,
-0.010039596818387508,
0.0864... |
precedes\n\tthe\tonset\tof\thypertension\tis\tunclear.\tWeight\tloss,\texercise,\tand\ta\tMeD-style\tdiet\tare\nbeneficial\t(see\t\nAppendix\t23\n).\nVirtually\tall\tclinical\ttrials\ton\tweight\treduction\tand\tblood\tpressure\tsupport\tthe\tefficacy\tof\tweight\nloss\ton\tlowering\tblood\tpressure.\tReductions\tin\tb... | [
-0.01787760481238365,
-0.005578723270446062,
0.08094210922718048,
-0.02506815828382969,
-0.12270554900169373,
0.02748480625450611,
0.02541491575539112,
0.001112167490646243,
0.004475160967558622,
0.06426045298576355,
0.09247639030218124,
-0.023086359724402428,
0.026653101667761803,
-0.0306... |
desirable\tbody\tweight\tin\tmost\tparticipants.\tLarger\tblood\tpressure\treductions\tare\tachieved\n\tin\nparticipants\twho\tlost\tmore\tweight\tand\twere\talso\ttaking\tantihypertensive\tmedications.\tThis\tlatter\nfinding\tsuggests\ta\tpossible\tsynergistic\teffect\tbetween\tweight\tloss\tand\tdrug\ttherapy.\tAltho... | [
0.021724998950958252,
-0.038503143936395645,
0.05672680214047432,
0.05401372164487839,
-0.09003520756959915,
0.00922004971653223,
0.08444128185510635,
0.050789326429367065,
-0.05874922499060631,
0.056360721588134766,
0.08762858808040619,
-0.06471312791109085,
0.0012167854001745582,
0.02792... |
reduction\tand\tmaintenance\tof\ta\thealthy\tbody\tweight\tis\ta\tmajor\teffort,\tinterventions\tto\tprevent\nweight\tgain\tare\tneeded\tbefore\tmidlife.\tIn\taddition,\tBMI\tis\trecommended\tas\ta\tscreening\ttool\tin\nadolescence\n\tfor\tfuture\thealth\trisk\t(\nFlynn\tet\tal,\t2017\n).\nSodium\nEvidence\tfrom\ta\tva... | [
-0.013808690011501312,
0.02251170575618744,
0.06855741143226624,
-0.03868410736322403,
-0.042251106351614,
0.005061245057731867,
0.07642029225826263,
0.004968119785189629,
-0.032616063952445984,
0.07795053720474243,
0.08532524853944778,
-0.04088536277413368,
0.04886607825756073,
0.02004385... |
dietary\tsodium.\tFor\texample,\tin\tthe\tTrials\tof\tHypertension\tPrevention\tmore\tthan\t2400\tindividuals\nwith\tmoderately\televated\tblood\tpressure\twere\tassigned\trandomly\tto\teither\tcut\ttheir\tsodium\tby\t750\nto\t1000\tmg\tper\tday\tor\tto\tfollow\tgeneral\tguidelines\tfor\n\thealthy\teating\tfor\t18\tmon... | [
-0.06434625387191772,
-0.0454973429441452,
0.07023504376411438,
0.003628980368375778,
-0.04049099236726761,
-0.02541934698820114,
0.08924420922994614,
-0.0015319733647629619,
-0.07831843197345734,
-0.019103985279798508,
0.11521869152784348,
-0.0340481698513031,
0.03878377005457878,
-0.0160... |
healthy\teating\tfor\t18\tmonths\tto\t4\tyears.\tIn\t10\nto\t15\tyears\tafter\tthe\tstudies\tended,\tindividuals\twho\tcut\ttheir\tsodium\texperienced\ta\t32%\tlower\trisk\nof\theart\tattacks,\tstrokes,\tor\tother\tcardiovascular\tevents\tcompared\twith\tthe\tgroup\tthat\tdid\tnot\t(\nCook\net\tal,\t2014 | [
-0.021763784810900688,
-0.05593489855527878,
0.08981283754110336,
0.008947404101490974,
-0.06698168069124222,
-0.01567911170423031,
0.09404166042804718,
0.012087613344192505,
-0.048528097569942474,
0.03316617012023926,
0.08796749264001846,
-0.016004109755158424,
0.03512472286820412,
0.0218... |
Cook\net\tal,\t2014\n).\tA\tmeta-analysis\tof\t37\tRCTs\tfurther\tsupports\tthe\tpositive\teffects\tof\tsodium\treduction\ton\nblood\tpressure\tand\tcardiovascular\toutcomes\tfor\n\tnormotensive\tand\thypertensive\tindividuals\t(\nAburto\net\tal,\t2013\n). | [
-0.035400308668613434,
-0.0741947665810585,
0.024833526462316513,
0.009951489977538586,
-0.05158485472202301,
-0.00396144762635231,
0.073310986161232,
0.04939369112253189,
-0.005633224733173847,
0.009985161013901234,
0.0842817947268486,
-0.07016463577747345,
-0.05459055304527283,
0.0503553... |
The\tDASH\tsodium\ttrials\ttested\tthe\teffects\tof\tthree\tdifferent\tlevels\tof\tsodium\tintake\t(1500\tmg,\n2400\tmg,\tand\t3300\tmg/day)\tcombined\twith\teither\ta\ttypical\tU.S.\tdiet\tor\tthe\tDASH\tdiet\tin\tpersons\nwith\tprehypertension\tor\tstage\t1\thypertension\t(\nAppel\tet\tal,\t2006\n).\tThe\tlowest\tblo... | [
-0.04639139771461487,
-0.05917844548821449,
0.04874066635966301,
0.03973434492945671,
-0.06348962336778641,
-0.04265282675623894,
0.11197863519191742,
0.04959777742624283,
-0.04239710792899132,
-0.006912224926054478,
0.08568049967288971,
-0.021039852872490883,
0.07510746270418167,
0.029672... |
achieved\tby\tthose\teating\tthe\t1500-mg\tsodium\n\tlevel\tin\tthe\tDASH\tdiet.\tIn\tthe\tDASH\tdiet\tand\tthe\ntypical\tAmerican\tdiet\tgroups,\tthe\tlower\tthe\tsodium,\tthe\tlower\tthe\tblood\tpressure.\tSuch\tdata\tprovide\nthe\tbasis\tfor\tthe\t2018\tACC/AHA\t(\nWhelton\tet\tal,\t2018\n)\tsodium\tguideline\tfor\t... | [
-0.011627799831330776,
-0.013631382025778294,
0.06558424979448318,
-0.042359109967947006,
-0.07024246454238892,
0.006683093495666981,
0.07468486577272415,
-0.028547532856464386,
-0.04528377950191498,
0.03878285735845566,
0.0877753421664238,
-0.018419401720166206,
0.09264186024665833,
-0.00... |
Whelton\tet\tal,\t2018\n)\tsodium\tguideline\tfor\tmost\tadults\tto\taim\tfor\tat\nleast\t1000\tmg/day\treduction\tin\tsodium\tand\tfor\tadults\twith\televated\tblood\tpressure\tto\treduce\tsodium\nto\tan\toptimal\tgoal\tof\t<1500\tmg/day.\tFor\tthose\twith\n\tnormal\tblood\tpressure,\tthe\tDietary\tGuidelines | [
-0.016590679064393044,
-0.011729962192475796,
0.037308476865291595,
-0.008237090893089771,
-0.029380042105913162,
-0.06785660982131958,
0.07731591910123825,
0.0009519999730400741,
-0.036315448582172394,
0.016738558188080788,
0.08476673066616058,
-0.02479647845029831,
0.04798632115125656,
0... |
normal\tblood\tpressure,\tthe\tDietary\tGuidelines\nfor\tAmericans\trecommend\tan\tintake\tof\tless\tthan\t2300\tmg\tof\tsodium,\tthe\tequivalent\tof\t6\tg\tof\tsalt,\neach\tday\t(\nUSDA,\t2015\n).\tThis\tgoal\tis\tsupported\tby\tthe\tAND\tPractice\tGuidelines\t(\nLennon\tet\tal,\t2017\n)\nand\tother\torganizations. | [
-0.014739948324859142,
-0.03196245804429054,
0.051129039376974106,
-0.02041771449148655,
-0.07869606465101242,
-0.016534820199012756,
0.05754644423723221,
-0.05513115972280502,
-0.012350044213235378,
0.05965668708086014,
0.12739264965057373,
-0.013086543418467045,
0.015694690868258476,
0.0... |
Lennon\tet\tal,\t2017\n)\nand\tother\torganizations.\nThere\tis\tagreement\tthat\tsome\tpersons\twith\thypertension\tshow\ta\tgreater\tdecrease\tin\ttheir\tblood\npressures\tin\tresponse\tto\treduced\tsodium\n\tintake\tthan\tothers.\tThe\tterm\tsalt-sensitive\thypertension\nhas\tbeen\tused\tto\tidentify\tthese\tindivid... | [
0.031611084938049316,
-0.04165876656770706,
0.0949508473277092,
-0.016926975920796394,
-0.017306165769696236,
0.03676409646868706,
0.10149440914392471,
0.006011174991726875,
-0.07824861258268356,
0.08131764829158783,
0.1240781843662262,
-0.0401352234184742,
0.051044732332229614,
-0.0560874... |
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