OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC11789597	All these cells were fixed with Fix I buffer (Standard BioTools) for 10 min at RT and barcoded separately using the Cell‐ID 20‐Plex Pd Barcoding Kit (Standard BioTools).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10213179	From this analysis, 753 aptamer candidates were identified from the cell-internalization SELEX and 857 aptamer candidates were identified from the protein SELEX that exhibited continuous positive log2FC enrichment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10587429	Summary of the number and recovery rate of CD34+ cells from healthy donors’ cord blood. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Summary", "of", "the", "number", "and"...
PMC11741906	Pathways in cancer were the pathways in which the miRNAs were predicted to have the most significant impact, with the largest number of genes targeted by these miRNAs belonging to this pathway.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11093197	The tumor suppressor p14 is considered a p53 activator and stabilizes and stimulates p53 activity by inhibiting MDM2 and ARF‐BP1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "tumor", "suppressor",...
PMC11638255	Schematic created in BioRender.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Schematic", "created", "in", "BioRender", "." ] } ]
PMC10748106	A greater number of susceptible regions to electrophilic and nucleophilic attacks are observed in glycosylated iridoids.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "greater", "number", "of", "susceptible", "regions...
PMC10955424	It is interesting to note that poor prognosis and overexpression of fatty acid synthase (FASN) was significantly correlated with OC patients' tumor grade, stage, and poor prognosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Improved HRQoL scores were statistically significant for ide-cel vs BM at 6 and 9 months for the QLQ-C30 fatigue domain (HRQoL scores were numerically better for ide-cel vs BM at all other time points).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11769516	The found that the inhibition of protein synthesis leads to neuronal and neurochemical disorders and many brain dysfunctions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "found", "that", "the", "inhibit...
PMC11321678	Then, new fragments, and bam files without multiplets were got.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "new", "fragments", ",", "and", "bam", "files", "without", "mu...
PMC9429973	Molecular tests for detection for JAK2, MPL and CALR mutations were performed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Molecular", "tests", "for", "detection", "for", "JAK2", ",", "MPL", "...
PMC7840816	TPC-1 and BCPAP cells transfected with siRNA-SOX9 were seeded into 100-mm petri dishes with soft agar.	[ { "tags": [ "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TPC-1", "and", "BCPAP", "cells", "transfec...
PMC10944868	Analytical TLCs were performed with silica gel 60 F254 plates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Analytical", "TLCs", "were", "performed", "with", "silica", "gel", "60", "F254", "plates", ...
PMC11411131	The effect of additional Krab on the MeHg sensor was examined using Krabx2-Sec, which includes TetR, Sec, and a Krab tandem repeat.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11502443	Data points are the mean ± s. e.m of the combined data from 3 (pAKT, pERK1/2 and pCREB) or 5 (cAMP and IP1) independent experiments. *	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Objectives included safety and overall response rate (ORR) of each combination.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Objectives", "included", "safety", "and", "overall", "response", "rate", "(...
PMC11683130	At present, most serpins focus on the pathogenesis of psoriasis vulgaris.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "present", ",", "most", "serpins", "focus", "on", "the", "pathogenesis", ...
PMC9429973	TBI 2-3 Gy was incorporated in conditioning for mismatched unrelated BMT for FA and in all haplo.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TBI", "2", "-", "3", "Gy", ...
PMC11127909	G plasmids for 48 h. Initially, we seeded 293 T cells in a 75 cm cell culture dish and allowed them to reach 90% confluence.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11545737	This disease course correlates with apoptotic cell death of naïve macrophages and, later in the infection, with pyrototic cell death of activated macrophages .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9964635	77–78 °C; IR (KBr) cm: 3272.76, 2963.13, 1640.12, 1604.83, 1466.29, 1366.62, 906.66, 686.83.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11279397	Luteolin effectively targeted the post-attachment stage of EV71 and CA16 infections by suppressing viral RNA replication .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Luteolin", "effectively", "targeted", "the", "post-attachmen...
PMC8903741	Sandwich ELISA for conforming the activity of purified antibody was performed as follows: 200 ng of purified anti-hMMP9 antibody or commercially available mouse anti-hMMP9 antibody (Sino Bio-logical Inc, Beijing, China) was immobilized on the 96-well plate for 16 h at 4 °C, and the well was filled with 200 μL of PBST (PBS buffer with 0.05% Tween 20) that contains 2% BSA for 1 h at 37 °C and washed three times with 200 μL of TBST (TBS buffer with 0.05% Tween 20).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10728200	Dysfunctional ubiquitin E3 ligase expression determines ubiquitination specificity and rate-limiting steps, playing a crucial role in tumor development .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Dysfunctional", "ubiquitin", "E3", ...
PMC11727062	Consequently, research into herbal monomers derived from Cornus officinalis may yield potential drugs capable of combating drug-resistant melanoma.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consequently", ",", "research", "...
PMC11725127	These findings collectively suggested the specific interaction between GA and USP2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "findings", "collectively", "suggested", "the", "specific", "interaction", "between", ...
PMC10565698	circRNAs contain several miRNA-binding sites and can enhance the expression of target genes by adsorbing miRNAs, thus relieving the repressive effects of miRNAs on their target genes .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11618052	The results indicated that most evaluated compounds exhibited strong antiproliferative activity, with Vb, Vc, Vh, Vk, and Vl demonstrating the highest potency.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11267036	To determine whether there is a connection between the STAT1/RIG-I pathway and MM, the mRNA expression of STAT1 and RIG-I and protein expression of STAT1, p-STAT1, and RIG-I were assessed in human MM and normal plasma samples.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9918897	However, since beer contains a variety of other polyphenolic compounds , it is also regarded as a significant source of dietary antioxidants.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However...
PMC5025404	Part of a strategy to develop the pharmaceutical industry in Russia includes reducing the dependence of the Russian market on imported drugs and improving the availability of new drugs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	VEN has shown preclinical and clinical activity in relapsed T-ALL/LBL.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "VEN", "has", "shown", "preclinical", "and", "clinical", "activity", "in", "relapsed", "T-ALL/LBL...
PMC9635307	Given CEACAM1 suppression of BCR signaling activation, the transfectants were subjected to cell proliferation assay to evaluate whether such effect was substantial.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Given",...
PMC11696576	b Correlation matrix shows the Pearson correlations corr (a, b) between all compound pairs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "b", "Correlation", "matrix", "shows", "the", ...
PMC11769516	The mechanisms underlying the neurotoxicity of the described mycotoxins were presented.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mechanisms", "underlying", "the", "neurotoxicity", "of", "the", "described", "mycoto...
PMC10452486	They are QFAYDGKDY (present in all alleles of HLA-A, -B, –C, -E, -F, and -G loci) and DTAAQI (present in HLA-B and HLA-C) (Figure 3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: We report the case of CLPD-NK with liver infiltration, extreme splenomegaly and direct Coombs negative hemolytic anemia.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "We", "rep...
PMC9429973	Results: As of the data-cut-off date of 23 Feb 2022, 6 pts with r/r B-NHL (DLBCL: 2, PMBCL: 1, FL: 2, MCL: 1) were treated with CB-010 at the initial dose level of 40 x10 CAR-T cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11343332	The following observations were made: In the control group, untreated cancer cells migrated to almost half of the scratched area after 24 hours.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9672323	Significant changes are indicated with asterisk (p < 0.05, p < 0.01, p < 0.001, **p < 0.0001).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11632064	Also, opposite to A-375, MeWo cells are classified as MITF and PGC-1α positive cells (Vazquez et al, 2013), which aligns well with the importance of mitochondrial programs in their resistance phenotype.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8193813	The UAS–Kolibri NOx emission factor for Midland is 8% higher than the simultaneous CEMS value.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "UAS", "–", "Kolibri", "NOx", ...
PMC11519077	Numerous studies have demonstrated that after cell or tissue damage, MSCs can be triggered by cytokines associated with inflammation, move to the area of damage, and regulate the tissue-regeneration process by secreting a variety of substances that may promote the growth and development of progenitor cells while reducing inflammatory responses .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6684588	Data are means ± SEM (n = 5). ***	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "means", "±", "SEM", "(", "n", "=", "5", ")", ...
PMC11773391	Relevant studies indicate that the MAPK signalling pathway may be associated with the overexpression of MGMT, which may be a potential way to obtain TMZ resistance .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9351137	We also tested the histone variant H2A.Z, which replaces the canonical histone H2A, due to the action of SRCAP and p400/Tip60 complexes .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9027909	Similar to mir-16, mir-21 seems to be associated with the impaired functions of intestinal barrier.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Similar", "to", "mir-16", ",", "mir-21", "seems", ...
PMC9429973	Patients with CAD were previously shown to have a greater healthcare utilization compared to the general population (Vago.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "with", "CAD", "were",...
PMC11739484	In total 13 SKCM cell lines, including A375, SK-MEL-2, SK-MEL-5, SK-MEL-28, SK-MEL-31, SK-MEL-37, SK-MEL-119, SK-MEL-147, SK-MEL-187, SK-MEL-239, WM115, WM266-4, WM793 and 07 control skin cell lines, including HaCaT, NHDF-AD, HEK293T, HUVEC, BJ, NHEK, and HDFa were purchased from the ATCC.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine...
PMC9429973	Inhibition of menin is therefore a novel approach to cancer treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Inhibition", "of", "menin", "is", "therefore", "a", "novel", "approach", "to", "cance...
PMC10932641	No adverse events occurred in nude mice during the experiment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "adverse", "events", "occurred", "in", "nude", "mice", "during", "the", "experiment", ...
PMC11594588	Oxidative changes in biomolecules inducing tissue damage leads to inflammation, initiating pathogenic processes associated with faster cell aging or their apoptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Oxidative", ...
PMC9429973	Methods: We generated UCART20x22, allogeneic CAR T-cells targeting CD20 and CD22, using a bicistronic lentiviral construct to express both CARs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Methods...
PMC11612508	In the case of T98 cells, as illustrated in Figs. 9 and Figs. 10(e–f), the proximity of GO/CS/IO magnetic microspheres in the absence of a magnetic field does not significantly affect cell viability compared to the untreated control group.	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10335954	C TRIP13 regulation of downstream genes Differences in TRIP13 expression related to different gene pathways in cancer Enrichment plots from GSEA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "C", "TRIP13", "re...
PMC11342785	The curves were determined by fitting to a one-phase decay equation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "curves", "were", "determined", "by", "fitting", "to", "a", "one-phase", "decay...
PMC10170482	Cells (Alexander and HepG2) were cultured in CS and MC models for 7 days.	[ { "tags": [ "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "(", "Alexander", "and", "HepG2", ...
PMC10114490	According to this limited analysis, we considered our cells between immature and mature hepatocytes under standard cell culture conditions (Fig. 3B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11089031	The expression of ZNF692 was associated with poor overall survival.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "expression", "of", "ZNF692", "was", "associated", "with", "poor", "overall", "survival", ...
PMC9960565	C-NMR (100 MHz, D2O) [ppm]: δ= 30.08 (Cc + Ci + Co + Cu), 34.13 (Cr), 36.01 (Cf + Cl), 48.68 (Ct), 50.41 (Ca + Cg + Cm + Cs), 51.11 (Cb + Ch + Cn), 174.33 (Cd), and 177.30 (Cp).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8557138	Several ex vivo assays including rat aortic ring assay, chick aortic arch assay, and mouse fetal metatarsal angiogenesis assays have been employed for anti-angiogenic drug screening and to elucidate molecular mechanisms governing tumor angiogenesis (Tufan and Satiroglu-Tufan 2005).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11092382	Among such products, the alkaloids found in the bark, root, leaf, seed, flower, or other parts of the plant are among the largest and most important groups of naturally occurring organic molecules, and constitute the active ingredients of the crude medical source (Omar et al., 2021).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10747160	However, an oft-overlooked aspect of SARS-CoV-2 infection is viral capture by attachment receptors such as DC-SIGN, which is thought to facilitate the initial stages of COVID-19 infection in the lung tissue (called trans-infection).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11472639	Despite the limitations of the study, the results have other important clinical implications.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Despite", "the", "limitations", "of", "the", "study", ",", "the"...
PMC9429973	The antibiotic sensitivity pattern is shown in the figure.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "antibiotic", "sensitivity", "pattern", "is", "shown", "in", "the", "figure", "." ] } ]
PMC11395280	In addition, there is some evidence that like B-cell ALL, T-ALL may migrate from the bone marrow directly into the CNS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC7961460	Intriguingly, significant association of c10orf118 with survival data (OS, RSF and DMSF) were recorded in the ER+ patients (Figure 8B panel II, III and IV, respectively) compared to all patients (data not shown).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11703896	In Hela cancer cell line also rapamycin showed significant cytotoxicity, however it was lower than that on A549 cell line.	[ { "tags": [ "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "In...
PMC9884169	RNA-seq showed that the autophagy pathway was enriched after the knockdown of MCT4 by KEGG enrichment analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RNA-seq", "showed", "that", "the", "autophagy", ...
PMC11653533	In a study by Choo et al., two bioactive flavonoids, vitexin and isovitexin, were isolated from the leaves of Ficus deltoidea.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11615828	The normalized mean speed of VAMP2‐positive vesicles upon temporal blue light illumination (blue) in (e).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "normalized", "mean", "spee...
PMC10955424	RJY13 induced resistance was determined using cPARP immunoblotting (A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RJY13", "induced", "resistance", "was", "determined", "using", "cPARP", "immunoblotting", "...
PMC8073654	The circular dichroism data for these compounds, for which their absolute configurations were established, have provided an excellent reference for determining the stereochemistry of phenylbutenoid dimers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11224020	Data were analyzed by ordinary one-way ANOVA; ****P < 0.0001.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "were", "analyzed", "by", "ordinary", "one-way", "AN...
PMC8875242	The evaluation of a drug’s ability to inhibit ABCB1 is complicated by the presence of several transport-competent sites within the ABCB1 binding pocket, making it difficult to select appropriate substrates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	A patient from cohort 3, had at D+120 disease progression with two distant enhancing lesions, and increased tumor necrosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "patient", "f...
PMC11718809	The unique structure and distinct localization of circRNAs endow them with specific biological functions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "unique", "structure", "and", "distinct", "localization", "of", ...
PMC9429973	ISSIII and R–ISS III were 70.8 % and 62.5 % respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ISSIII", "and", "R", "–", "ISS", "III", "were", "70.8", "%", "a...
PMC11733919	Indeed, cellular senescence is also considered as a side effect of chemotherapy, ultimately limiting the elimination of both nonsenescent and senescent cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11266100	Thus, we demonstrate an efficient electrotransfection methodology for mammalian cells using high-frequency pulsed electric fields (PEFs), which represents a significant enhancement over standard existing GET methodologies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11392912	The total miRNA isolated from four different medicinal valued plant also shown on agarose gel along with clo-mir-14 as positive control (Figure 1D). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11633763	Similarly, USP22 and HK2 protein expression levels showed a strong positive association (Figure 4K).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Similarly", ",", "USP22", "and", "HK2"...
PMC9429973	Given its role as main antioxidant in the extracellular space and its potential anti-inflammatory/anti-thrombotic properties, higher-albumin levels could be associated with an increased capability to counteract MF-associated inflammation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3164356	We next investigated this property using the CHO-K1 genome and transcriptome.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "We", "next", "investigated", "this", "property", "using", "the", "CHO-K1", "genome...
PMC11525293	All cells were maintained in DMEM enriched with 10% fetal bovine serum (Euroclone #ECS0165L), 1 mM l-glutamine (Euroclone #ECB3000D), 100 units/mL penicillin, and 100 μg/mL streptomycin (Euroclone #ECB3001D) at 37 °C in a humidified atmosphere of 5% (v/v) CO2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11261875	•Enhanced glycolysis in GIST is an important metabolic feature.•GLUT play a significant role in GIST progression and response to treatment.•Glycolysis can lead to the therapeutic strategies for GIST.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9587298	The supernatants were collected and pooled, and the final volume was adjusted to 200 mL. The initial extract (E) was further fractioned by SPE using a C18 cartridge (Supelco SPE pack, Sigma-Aldrich), as reported by Ferreira, Silva, and Nunes (2018).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11515150	5D-Fc and 12 C-Fc were administrated to test the binding ability using flow cytometry. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "5D-Fc", "and", "12", "C-Fc", "were", "administrated", "to",...
PMC11453018	Mice were identified by number, and the investigator was blinded to the treatment status during tumor dissection, weighing, and photographing.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mice", ...
PMC9429973	Methods: AML cell lines (n=11) and frozen mononuclear cells, extracted from AML (n=27) and very high risk MDS (n=4) patient bone marrow (BM) aspirates provided by the Finnish Hematology Registry and Biobank, were used in this study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11782508	The strong N-H stretching bands observed at 3439 cm⁻¹ and 3429 cm⁻¹ indicate hydrogen bonding, further supporting the protein’s folded, stable conformation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11791432	Likewise, no statistical difference was observed in GBM subgroup of CGGA_325 in survival analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Likewise", ",", "no", "statistical", "difference", "was", "...
PMC11718817	After 15–20 min of incubation at 37 °C and 5% CO2, 300 µL complete RPMI 1640 medium was added.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "15–...
PMC11704834	As shown in Fig. 3Dc, ectopic E-cadherin expression significantly increased the level of gefitinib-induced apoptosis in exogenous TLE1 expressing A549 cells, indicating partial restoration of their gefitinib sensitivity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", ...
PMC11045125	The PCR program was as follows: 98°C for 30 sec, followed by 35 cycles of 98°C for 10 sec, 62°C for 20 sec, and 72°C for 1 min, followed by a 5 minute polishing step at 72°C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	All patients discontinued immunosuppressive therapy and received 2, 1 and 4 courses of DLI with blinatumomab, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "patients", "discontinued", ...
PMC11538390	Expression levels of IRF6 are normalized against ACTB, GAPDH, HPRT, UBC and CDH1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Expression", "levels", "of", "IRF6", "are", "normalize...
PMC11591038	Among various causes, AD may comprise 60–70% of dementia cases (https://www.who.int/news-room/fact-sheets/detail/dementia, accessed on 15 March 2023).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Among", "various", ...
PMC11499381	However, the lower fluorescence output we observed with N-terminal fusion should be considered as a potential limitation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "lower", "fluore...

PMC11789597

All these cells were fixed with Fix I buffer (Standard BioTools) for 10 min at RT and barcoded separately using the Cell‐ID 20‐Plex Pd Barcoding Kit (Standard BioTools).

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PMC10213179

From this analysis, 753 aptamer candidates were identified from the cell-internalization SELEX and 857 aptamer candidates were identified from the protein SELEX that exhibited continuous positive log2FC enrichment.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10587429

Summary of the number and recovery rate of CD34+ cells from healthy donors’ cord blood. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Summary", "of", "the", "number", "and"...

PMC11741906

Pathways in cancer were the pathways in which the miRNAs were predicted to have the most significant impact, with the largest number of genes targeted by these miRNAs belonging to this pathway.

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PMC11093197

The tumor suppressor p14 is considered a p53 activator and stabilizes and stimulates p53 activity by inhibiting MDM2 and ARF‐BP1.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "tumor", "suppressor",...

PMC11638255

Schematic created in BioRender.

[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Schematic", "created", "in", "BioRender", "." ] } ]

PMC10748106

A greater number of susceptible regions to electrophilic and nucleophilic attacks are observed in glycosylated iridoids.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "greater", "number", "of", "susceptible", "regions...

PMC10955424

It is interesting to note that poor prognosis and overexpression of fatty acid synthase (FASN) was significantly correlated with OC patients' tumor grade, stage, and poor prognosis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Improved HRQoL scores were statistically significant for ide-cel vs BM at 6 and 9 months for the QLQ-C30 fatigue domain (HRQoL scores were numerically better for ide-cel vs BM at all other time points).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11769516

The found that the inhibition of protein synthesis leads to neuronal and neurochemical disorders and many brain dysfunctions.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "found", "that", "the", "inhibit...

PMC11321678

Then, new fragments, and bam files without multiplets were got.

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PMC9429973

Molecular tests for detection for JAK2, MPL and CALR mutations were performed.

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PMC7840816

TPC-1 and BCPAP cells transfected with siRNA-SOX9 were seeded into 100-mm petri dishes with soft agar.

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PMC10944868

Analytical TLCs were performed with silica gel 60 F254 plates.

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PMC11411131

The effect of additional Krab on the MeHg sensor was examined using Krabx2-Sec, which includes TetR, Sec, and a Krab tandem repeat.

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PMC11502443

Data points are the mean ± s. e.m of the combined data from 3 (pAKT, pERK1/2 and pCREB) or 5 (cAMP and IP1) independent experiments. *

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PMC9429973

Objectives included safety and overall response rate (ORR) of each combination.

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PMC11683130

At present, most serpins focus on the pathogenesis of psoriasis vulgaris.

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PMC9429973

TBI 2-3 Gy was incorporated in conditioning for mismatched unrelated BMT for FA and in all haplo.

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PMC11127909

G plasmids for 48 h. Initially, we seeded 293 T cells in a 75 cm cell culture dish and allowed them to reach 90% confluence.

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PMC11545737

This disease course correlates with apoptotic cell death of naïve macrophages and, later in the infection, with pyrototic cell death of activated macrophages .

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PMC9964635

77–78 °C; IR (KBr) cm: 3272.76, 2963.13, 1640.12, 1604.83, 1466.29, 1366.62, 906.66, 686.83.

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PMC11279397

Luteolin effectively targeted the post-attachment stage of EV71 and CA16 infections by suppressing viral RNA replication .

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PMC8903741

Sandwich ELISA for conforming the activity of purified antibody was performed as follows: 200 ng of purified anti-hMMP9 antibody or commercially available mouse anti-hMMP9 antibody (Sino Bio-logical Inc, Beijing, China) was immobilized on the 96-well plate for 16 h at 4 °C, and the well was filled with 200 μL of PBST (PBS buffer with 0.05% Tween 20) that contains 2% BSA for 1 h at 37 °C and washed three times with 200 μL of TBST (TBS buffer with 0.05% Tween 20).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10728200

Dysfunctional ubiquitin E3 ligase expression determines ubiquitination specificity and rate-limiting steps, playing a crucial role in tumor development .

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PMC11727062

Consequently, research into herbal monomers derived from Cornus officinalis may yield potential drugs capable of combating drug-resistant melanoma.

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PMC11725127

These findings collectively suggested the specific interaction between GA and USP2.

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PMC10565698

circRNAs contain several miRNA-binding sites and can enhance the expression of target genes by adsorbing miRNAs, thus relieving the repressive effects of miRNAs on their target genes .

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PMC11618052

The results indicated that most evaluated compounds exhibited strong antiproliferative activity, with Vb, Vc, Vh, Vk, and Vl demonstrating the highest potency.

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PMC11267036

To determine whether there is a connection between the STAT1/RIG-I pathway and MM, the mRNA expression of STAT1 and RIG-I and protein expression of STAT1, p-STAT1, and RIG-I were assessed in human MM and normal plasma samples.

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PMC9918897

However, since beer contains a variety of other polyphenolic compounds , it is also regarded as a significant source of dietary antioxidants.

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PMC5025404

Part of a strategy to develop the pharmaceutical industry in Russia includes reducing the dependence of the Russian market on imported drugs and improving the availability of new drugs.

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PMC9429973

VEN has shown preclinical and clinical activity in relapsed T-ALL/LBL.

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PMC9635307

Given CEACAM1 suppression of BCR signaling activation, the transfectants were subjected to cell proliferation assay to evaluate whether such effect was substantial.

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PMC11696576

b Correlation matrix shows the Pearson correlations corr (a, b) between all compound pairs.

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PMC11769516

The mechanisms underlying the neurotoxicity of the described mycotoxins were presented.

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PMC10452486

They are QFAYDGKDY (present in all alleles of HLA-A, -B, –C, -E, -F, and -G loci) and DTAAQI (present in HLA-B and HLA-C) (Figure 3).

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PMC9429973

Aims: We report the case of CLPD-NK with liver infiltration, extreme splenomegaly and direct Coombs negative hemolytic anemia.

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PMC9429973

Results: As of the data-cut-off date of 23 Feb 2022, 6 pts with r/r B-NHL (DLBCL: 2, PMBCL: 1, FL: 2, MCL: 1) were treated with CB-010 at the initial dose level of 40 x10 CAR-T cells.

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PMC11343332

The following observations were made: In the control group, untreated cancer cells migrated to almost half of the scratched area after 24 hours.

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PMC9672323

Significant changes are indicated with asterisk (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001).

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PMC11632064

Also, opposite to A-375, MeWo cells are classified as MITF and PGC-1α positive cells (Vazquez et al, 2013), which aligns well with the importance of mitochondrial programs in their resistance phenotype.

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PMC8193813

The UAS–Kolibri NOx emission factor for Midland is 8% higher than the simultaneous CEMS value.

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PMC11519077

Numerous studies have demonstrated that after cell or tissue damage, MSCs can be triggered by cytokines associated with inflammation, move to the area of damage, and regulate the tissue-regeneration process by secreting a variety of substances that may promote the growth and development of progenitor cells while reducing inflammatory responses .

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PMC6684588

Data are means ± SEM (n = 5). ***

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PMC11773391

Relevant studies indicate that the MAPK signalling pathway may be associated with the overexpression of MGMT, which may be a potential way to obtain TMZ resistance .

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PMC9351137

We also tested the histone variant H2A.Z, which replaces the canonical histone H2A, due to the action of SRCAP and p400/Tip60 complexes .

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PMC9027909

Similar to mir-16, mir-21 seems to be associated with the impaired functions of intestinal barrier.

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PMC9429973

Patients with CAD were previously shown to have a greater healthcare utilization compared to the general population (Vago.

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PMC11739484

In total 13 SKCM cell lines, including A375, SK-MEL-2, SK-MEL-5, SK-MEL-28, SK-MEL-31, SK-MEL-37, SK-MEL-119, SK-MEL-147, SK-MEL-187, SK-MEL-239, WM115, WM266-4, WM793 and 07 control skin cell lines, including HaCaT, NHDF-AD, HEK293T, HUVEC, BJ, NHEK, and HDFa were purchased from the ATCC.

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PMC9429973

Inhibition of menin is therefore a novel approach to cancer treatment.

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PMC10932641

No adverse events occurred in nude mice during the experiment.

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PMC11594588

Oxidative changes in biomolecules inducing tissue damage leads to inflammation, initiating pathogenic processes associated with faster cell aging or their apoptosis.

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PMC9429973

Methods: We generated UCART20x22, allogeneic CAR T-cells targeting CD20 and CD22, using a bicistronic lentiviral construct to express both CARs.

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PMC11612508

In the case of T98 cells, as illustrated in Figs. 9 and Figs. 10(e–f), the proximity of GO/CS/IO magnetic microspheres in the absence of a magnetic field does not significantly affect cell viability compared to the untreated control group.

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PMC10335954

C TRIP13 regulation of downstream genes Differences in TRIP13 expression related to different gene pathways in cancer Enrichment plots from GSEA.

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PMC11342785

The curves were determined by fitting to a one-phase decay equation.

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PMC10170482

Cells (Alexander and HepG2) were cultured in CS and MC models for 7 days.

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PMC10114490

According to this limited analysis, we considered our cells between immature and mature hepatocytes under standard cell culture conditions (Fig. 3B).

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PMC11089031

The expression of ZNF692 was associated with poor overall survival.

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PMC9960565

C-NMR (100 MHz, D2O) [ppm]: δ= 30.08 (Cc + Ci + Co + Cu), 34.13 (Cr), 36.01 (Cf + Cl), 48.68 (Ct), 50.41 (Ca + Cg + Cm + Cs), 51.11 (Cb + Ch + Cn), 174.33 (Cd), and 177.30 (Cp).

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PMC8557138

Several ex vivo assays including rat aortic ring assay, chick aortic arch assay, and mouse fetal metatarsal angiogenesis assays have been employed for anti-angiogenic drug screening and to elucidate molecular mechanisms governing tumor angiogenesis (Tufan and Satiroglu-Tufan 2005).

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PMC11092382

Among such products, the alkaloids found in the bark, root, leaf, seed, flower, or other parts of the plant are among the largest and most important groups of naturally occurring organic molecules, and constitute the active ingredients of the crude medical source (Omar et al., 2021).

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PMC10747160

However, an oft-overlooked aspect of SARS-CoV-2 infection is viral capture by attachment receptors such as DC-SIGN, which is thought to facilitate the initial stages of COVID-19 infection in the lung tissue (called trans-infection).

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PMC11472639

Despite the limitations of the study, the results have other important clinical implications.

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PMC9429973

The antibiotic sensitivity pattern is shown in the figure.

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PMC11395280

In addition, there is some evidence that like B-cell ALL, T-ALL may migrate from the bone marrow directly into the CNS.

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PMC7961460

Intriguingly, significant association of c10orf118 with survival data (OS, RSF and DMSF) were recorded in the ER+ patients (Figure 8B panel II, III and IV, respectively) compared to all patients (data not shown).

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PMC11703896

In Hela cancer cell line also rapamycin showed significant cytotoxicity, however it was lower than that on A549 cell line.

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PMC9884169

RNA-seq showed that the autophagy pathway was enriched after the knockdown of MCT4 by KEGG enrichment analysis.

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PMC11653533

In a study by Choo et al., two bioactive flavonoids, vitexin and isovitexin, were isolated from the leaves of Ficus deltoidea.

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PMC11615828

The normalized mean speed of VAMP2‐positive vesicles upon temporal blue light illumination (blue) in (e).

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PMC10955424

RJY13 induced resistance was determined using cPARP immunoblotting (A).

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PMC8073654

The circular dichroism data for these compounds, for which their absolute configurations were established, have provided an excellent reference for determining the stereochemistry of phenylbutenoid dimers.

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PMC11224020

Data were analyzed by ordinary one-way ANOVA; ****P < 0.0001.

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PMC8875242

The evaluation of a drug’s ability to inhibit ABCB1 is complicated by the presence of several transport-competent sites within the ABCB1 binding pocket, making it difficult to select appropriate substrates.

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PMC9429973

A patient from cohort 3, had at D+120 disease progression with two distant enhancing lesions, and increased tumor necrosis.

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PMC11718809

The unique structure and distinct localization of circRNAs endow them with specific biological functions.

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PMC9429973

ISSIII and R–ISS III were 70.8 % and 62.5 % respectively.

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PMC11733919

Indeed, cellular senescence is also considered as a side effect of chemotherapy, ultimately limiting the elimination of both nonsenescent and senescent cancer cells.

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PMC11266100

Thus, we demonstrate an efficient electrotransfection methodology for mammalian cells using high-frequency pulsed electric fields (PEFs), which represents a significant enhancement over standard existing GET methodologies.

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PMC11392912

The total miRNA isolated from four different medicinal valued plant also shown on agarose gel along with clo-mir-14 as positive control (Figure 1D). (

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PMC11633763

Similarly, USP22 and HK2 protein expression levels showed a strong positive association (Figure 4K).

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PMC9429973

Given its role as main antioxidant in the extracellular space and its potential anti-inflammatory/anti-thrombotic properties, higher-albumin levels could be associated with an increased capability to counteract MF-associated inflammation.

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PMC3164356

We next investigated this property using the CHO-K1 genome and transcriptome.

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PMC11525293

All cells were maintained in DMEM enriched with 10% fetal bovine serum (Euroclone #ECS0165L), 1 mM l-glutamine (Euroclone #ECB3000D), 100 units/mL penicillin, and 100 μg/mL streptomycin (Euroclone #ECB3001D) at 37 °C in a humidified atmosphere of 5% (v/v) CO2.

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PMC11261875

•Enhanced glycolysis in GIST is an important metabolic feature.•GLUT play a significant role in GIST progression and response to treatment.•Glycolysis can lead to the therapeutic strategies for GIST.

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PMC9587298

The supernatants were collected and pooled, and the final volume was adjusted to 200 mL. The initial extract (E) was further fractioned by SPE using a C18 cartridge (Supelco SPE pack, Sigma-Aldrich), as reported by Ferreira, Silva, and Nunes (2018).

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PMC11515150

5D-Fc and 12 C-Fc were administrated to test the binding ability using flow cytometry. (

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PMC11453018

Mice were identified by number, and the investigator was blinded to the treatment status during tumor dissection, weighing, and photographing.

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PMC9429973

Methods: AML cell lines (n=11) and frozen mononuclear cells, extracted from AML (n=27) and very high risk MDS (n=4) patient bone marrow (BM) aspirates provided by the Finnish Hematology Registry and Biobank, were used in this study.

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PMC11782508

The strong N-H stretching bands observed at 3439 cm⁻¹ and 3429 cm⁻¹ indicate hydrogen bonding, further supporting the protein’s folded, stable conformation.

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PMC11791432

Likewise, no statistical difference was observed in GBM subgroup of CGGA_325 in survival analysis.

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PMC11718817

After 15–20 min of incubation at 37 °C and 5% CO2, 300 µL complete RPMI 1640 medium was added.

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PMC11704834

As shown in Fig. 3Dc, ectopic E-cadherin expression significantly increased the level of gefitinib-induced apoptosis in exogenous TLE1 expressing A549 cells, indicating partial restoration of their gefitinib sensitivity.

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PMC11045125

The PCR program was as follows: 98°C for 30 sec, followed by 35 cycles of 98°C for 10 sec, 62°C for 20 sec, and 72°C for 1 min, followed by a 5 minute polishing step at 72°C.

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PMC9429973

All patients discontinued immunosuppressive therapy and received 2, 1 and 4 courses of DLI with blinatumomab, respectively.

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PMC11538390

Expression levels of IRF6 are normalized against ACTB, GAPDH, HPRT, UBC and CDH1.

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PMC11591038

Among various causes, AD may comprise 60–70% of dementia cases (https://www.who.int/news-room/fact-sheets/detail/dementia, accessed on 15 March 2023).

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PMC11499381

However, the lower fluorescence output we observed with N-terminal fusion should be considered as a potential limitation.

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