Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
Community
1
PMCID
string
Sentences
string
ner
list
PMC9512971
The events and reasons for censoring patients in this analysis are defined in Additional file 2: Table S4.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "events", "and", "reasons",...
PMC9429973
Differential expression gene (DEG) analysis identified five tumor-specific gene candidates and the cell surface protein PLS3 was validated by flow cytometry (Figure 3). (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9684669
The relative chemiluminescence intensity of each sample at different temperatures was used to plot the temperature dependent melting curve.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "relative", "chemiluminescence", ...
PMC8956657
Antibodies, rabbit anti-Flag (cat# F7425), and mouse anti-β-tubulin (cat# T8328) were purchased from Sigma-Aldrich.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Antibodies", ...
PMC11286266
Successfully rescued single clones by CRISPR/Cas9-mediated homology-directed repair (HDR) were evaluated in the absence (pale colour) and presence of ER stress (0.5 µM Tg, 5 hr, dark colour).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11541241
When they inoculated these transgenic potato lines with P. infestans, the transgenic lines showed increased resistance to late blight, indicating that the sRNA generated by the transgenic plants could be absorbed by P. infestans and induce the RNAi effect.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
A dose escalation stage assessed single-agent zandelisib daily continuously and is not reported here (Soumerai et al, J Clin Oncol 2018;36:#7519).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11483468
For the immunofluorescence assay, all treated cells were extensively washed with PBS, immobilized in cold methanol for 3 min, permeated with PBS for 10 min, and then sealed with new goat serum in PBS for 10 min.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11609529
Statistical analyses were conducted using GraphPad Prism 10.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "analyses", "were", "conducted", "using", "GraphPad", "Prism", "10", "." ] } ]
PMC6181431
To our knowledge no previous study has examined molecular mechanisms of acquired or secondary resistance of rapalog therapy in responding patients with RCC.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", ...
PMC11126803
ERβ, estrogen receptor β; LncRNA, long noncoding RNA; RCC, renal cell carcinoma; TCGA, The Cancer Genome Atlas.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC7090062
The 3’-untranslated region (UTR) and mutated 3’-UTR of the amplified BECN1 fragment was cloned into the pGL3 vector containing the firefly luciferase reporter gene (Promega, Madison, WI, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5673955
These cells remained alive, but they lost their ability to divide, which was confirmed by G0/G1 cell cycle arrest and reduction in a number of cells in S and G2/M phases (Fig. 5).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10587429
These models fail to reflect the highly metastatic nature of this bone and soft tissue tumor, because ES cells injected subcutaneously do not metastasize.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11754436
cck8 assay was performed to detect the proliferation and apoptosis levels of MG63 cells after co-transfection with DHRS4-AS1 and miR-362-5p mimic, *Represent comparison with the mNC group, # represents comparison with the mm group. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5535901
Total RNA was isolated using TRIzol reagent (ThermoFisher Scientific, Grand Island, NY, USA) and cDNA was synthesized using AffinityScript Multiple Temperature cDNA Synthesis kit (AgilentTechnologies, Santa Clara, CA, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11507371
The protocol for the subsequent quantitative PCR (qPCR) was optimised for a 12 μL reaction volume using 6 μL SensiFAST SYBR No-ROX Mix (Bioline/Meridian Bioscience Inc., Cincinnati, OH, USA), 5 μL cDNA, and 1 μL primers (sense and antisense).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11786600
Examination of the length of diabetic wounds stained with H&E (n = 3). (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Examination", "of", "the", "length", "of", "diabetic",...
PMC9096373
Survival times, which started from the first day post-administration, were observed until death.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Survival", "times", ",", "which", "started", "from", "the",...
PMC11092382
A clinically feasible agent must have been tested in both clinical and toxicological studies.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "clinically", "feasible", "agent", "must", "have", "been", "...
PMC11763111
p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001; ns, not significant LLT1 overexpression renders resistance to allogenic NK cell-mediated lysis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10218459
For each cell line, 2 × 10 cells per 200 µL of full medium were transferred to 6 wells of a 24-well plate.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11740399
Quantitative analysis of the PKM2, FASN, p-AKT, and p-mTOR proteins. *
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Quantitative", "analysis", "of", "the", "PKM2", ",", "FASN", ","...
PMC11643491
We chose to employ the film-stretching approach as we found it had the best capability to optimize the production of anisotropic particles across different sizes and stretch levels using a variety of polymers.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8526701
Prism VI software was used for statistical analyses.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Prism", "VI", "software", "was", "used", "for", "statistical", "analyses", "." ] } ]
PMC11544122
Receptor endocytosis was measured as described above.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Receptor", "endocytosis", "was", "measured", "as", "described", "above", "." ] } ]
PMC11670407
The Matrigel was thawed, diluted, and added to the growth surface of the transwell chamber (Labselect, Hangzhou, China) followed by resting at 37˚C for 1 h. The 143B cells and U2OS cells in the logarithmic growth phase were collected to perform trypsin digestion and serum-free medium resuspension.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11365427
In RPMI-8226 cells, we identified 114 differential genes, with 80 upregulated and 34 downregulated genes.
[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "RPMI-8226", "cells", ",", "we", ...
PMC9429973
Results: Median age at time of ibrutinib treatment initiation was 74.0 years for the 1L pts in C1, and 72.5 and 73.0 years in the R/R cohorts of C2 and C3, respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11564322
In neutrophils isolated from the blood of healthy subjects, the 1 µg/mL concentration of the VGVAPG peptide increased cell migration, while no significant changes in cell migration were observed in neutrophils obtained from patients with chronic obstructive pulmonary disease (COPD) (characterized by persistent inflammation) .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11392912
For quantification, cDNA of commercially available Clo-miR-14 was synthesized and amplified by PCR using different concentration in order to generate a standard curve (Figure 3A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9739791
Measurement of riboflavin excited state lifetime using time-correlated single photon counting (TCSPC) ruled out riboflavin excited state as an active catalyst.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Measure...
PMC11787355
f Overall survival of i.c.
[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "f", "Overall", "survival", "of", "i.c", "." ] } ]
PMC11129910
Claudin1 was lowered very significantly in both transformed cell lines, RAO-4 and HMEC 5.6 Clone#5, suggesting that the combination of the loss of RAB25 and overexpression of H-RAS61L leads to the development of a mesenchymal, claudin-low tumor phenotype.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC11367146
For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11772585
Recent evidence suggests that this modification is linked to the development of several cancers, making it a promising target for cancer therapy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Recent"...
PMC11622247
Increasing amounts of target RNA were added to probes C7-2AF568-QB-OMe and C7-QB-OMe in PBS and the fluorescence intensity at 600 nm was measured (Fig. 5A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8992508
These 6,7-dimethoxytetrahydroisoquinoline derivatives were modified on the anthranilic acid amide which was decorated with different functional groups (aromatic, heterocyclic or chain structures).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11767817
Firstly, the effect of MK-2206 (8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo [3,4-f]naphthyridin-3(2H)-one dihydrochloride) on 5637 cell viability used in monotherapy was investigated.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Firstly", ",", "the...
PMC11723947
Since their initial approval in melanoma, these compounds have dramatically improved outcomes for cancer patients, including those suffering from hematologic malignancies.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Since",...
PMC11656048
These data suggested that Nrf2 overexpression rescued ferroptosis and phenotypic changes induced by shikonin.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "data", "suggested", "that", "Nrf2", "overexpression", "rescue...
PMC11564322
mTOR and PPARγ proteins are involved in the mechanism of action of VGVAPG and VVGPGA peptides. •
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "mTOR", "and", "PPARγ", "proteins", "are", "...
PMC9429973
Patients who had previous BMAB experienced less pain.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "who", "had", "previous", "BMAB", "experienced", "less", "pain", "." ] } ]
PMC11267036
Increasingly studies reveal that DHM has the potential to mitigate some malignancies, including cholangiocarcinoma and esophageal squamous cell carcinoma by restraining EMT.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Increas...
PMC11792090
Monitoring of body weight ( Supplementary Figure S4B ) and H&E staining of major tissues ( Supplementary Figure S4C ) indicated that the high-dose injection of SAP UCAR-T cells did not raise any safety concerns.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11731161
Briefly, cell lysates from 5 × 10 cells were prepared with lysis buffer supplemented with protease inhibitors (Beyotime, China).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Briefly...
PMC11539788
D-E) western blot analysis of the levels of the RNF19A, ILK, and proteins involved in mTOR signalling in tumour samples from the LV-Control and LV-RNF19A groups. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10890307
Tumor cells cope with different gradients of oxygen tension, glucose, and glutamine.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tumor", "cells", "cope", "with", "different", "gradients", "of", ...
PMC5311252
Lentiviruses were produced by transfecting plasmids into the virus packing cell line HEK293T together with Gag-pol/Rev/Envelope VsV-g pantropic plasmid (a gift from Professor Thomas Helleday Lab at Karolinska Institutet).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11190538
The potent antitumor activity of C-phycocyanin reported in this study against HCT-116 and HepG-2 human cancer cells using the MTT assay with almost no cytotoxic activity towards the human healthy cell line (BJ-1) is of great interest.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC10759659
Our analysis revealed no significant difference in PD-L1 expression between the ARID1A deficiency and normal functioning groups.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Our", "analysis", "revealed", "no", "significant"...
PMC9895440
Cells were then strained through a 100 μm MACS SmartStrainer (Miltenyi) and washed using PBS with 2% FCS.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "...
PMC10887351
β1-and β3-ARs were reported in cancer processes, where β1-ARs promoted increased lipolysis in cancer cachexia and β3-AR missense mutations correlated with obesity in BC in African Americans .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11540664
Patients were divided into high- and low-L groups based on the median absolute count of peripheral blood lymphocytes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "were", "divided", "into", ...
PMC4270159
Please see Power Calculations for details.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Please", "see", "Power", "Calculations", "for", "details", "." ] } ]
PMC9635307
The results were expressed as the means ± standard error of the mean (SEM).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", "were", "expressed", "as", "the", ...
PMC11461874
In b, the center line denotes the median value.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "b", ",", "the", "center", "line", "denotes", "the", "median", "value", "." ] }...
PMC10999934
11,300 cells were divided into 20 separate clusters with resolution 0.8. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "11,300", "cells", "were", "divided", "into", "20", "separate", "clusters", "with...
PMC11799978
Therefore, targeting CAFs has become a promising new direction in cancer therapies.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "targeting", "CAFs", "has", "become", "a", "promising", ...
PMC9429973
We followed all patients registered with newly diagnosed CLL in the Danish CLL Register or the Danish Cancer Register in the period 2002-2018 from 1 month after CLL-diagnosis until death or end of follow-up.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10898159
Treatment with a specific ACK1 inhibitor AIM-100 or ACK1 siRNA markedly inhibits cell migration in imatinib sensitive and in imatinib resistant GIST cell lines, which is associated with inactivation of PI3K/AKT/mTOR and RAF/MAPK signaling pathways .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8143558
L.D. Benson, Taraxacum officinale F. H. Wigg.,
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "L.D.", "Benson", ",", "Taraxacum", "officinale", "F.", "H.", "Wigg", ".", "," ] } ]
PMC11694066
After 6 to 8 weeks, a partially homogeneous cell layer was obtained; from this primary culture, cells were washed with 1× PBS, dissociated in trypsin-EDTA solution (#25200056, Gibco), and seeded into a new culture flask for subsequent cell culture.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11790971
The three intensity-only channels (THG, SHG, and FAD) were collected using photon-counting PMTs (H7421-40, Hamamatsu) and time-resolved detection was used for the NAD(P)H channel in order to collect information on both intensity and fluorescence lifetime using a hybrid photodetector (PMA 40 Hybrid, PicoQuant) and a time-to-digital converter (HydraHarp 400, PicoQuant) for Time-Correlated Single Photon Counting (TCSPC).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11621493
In contrast to mammalian cells, PDAT reactions are well known in plants and yeast (39, 40, 41, 42, 43).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC5963610
The lower effect of this combination might results from a shorter persistence of the injected antibodies in circulation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "lower", "effect", "of", "this",...
PMC11701801
Strategies for cancer treatment based on the synthetic lethality between paralogs targeting one paralog in cancers with a mutation of another paralog have been proposed by many groups (10, 37–45).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10812665
Correlated activity scores were calculated on the Wald statistic (stat) using the weighted mean for all experimental conditions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Correlated", "activity", "sc...
PMC11741906
Moreover, several studies investigated the expression of miRNAs and linked the expression changes with resistance to chemotherapy [, , , ].
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreove...
PMC6948907
The MTT assay for determination of IC50 values for VPA with certain concentrations of VPA (0, 1, 5 and 10 μM/lit) which was dissolved in phosphate-buffered saline (PBS) was done.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9119314
Drug susceptibility assays were set up in 96-well, flat-bottom microplates in a final volume of 200 μL, as described previously (van Schalkwyk et al., 2017).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4277423
Most of the mutants contained deletions of −5 to −24 nucleotides.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Most", "of", "the", "mutants", "contained", "deletions", "of", "−5", "to", "−24", ...
PMC11464982
Batch used for the in vitro micronucleus test.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Batch", "used", "for", "the", "in", "vitro", "micronucleus", "test", "." ] } ]
PMC10778532
Using western blot, we confirmed the absence of expression of ZHX2 in cells transfected with the mix of siRNA ZHX2 (Figure 3A and Figure S2).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11351758
Cyclosporin A and its non-immunosuppressive analog N methyl-Val-4 cyclosporin A (PKF220-384) both inhibit opening and prevent the translocation of cyclophilin D from the matrix to the membranes of cortical mitochondria .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11760643
Briefly, tissue culture supernatant (TCSN) was collected from clone L4 and MPC‐11 cell lines.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Briefly", ",", "tissue", "culture", "supernatant"...
PMC9429973
Infection occurred more frequently on pacritinib versus BAT, though fungal and viral infections occurred less frequently, as did Herpes Zoster reactivation (pooled pacritinib: 0/100 patient-years vs BAT: 2.4/100 patient-years, including ruxolitinib: 5.5/100 patient-years).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11750712
Exclusion criteria are: general exclusion criteria: patients with T cell leukemia; females who are pregnant or lactating; prior treatment with investigational gene therapy or approved gene therapy or genetically engineered cell therapy product or allogeneic stem cell transplant; known history or presence of clinically relevant CNS pathology such as epilepsy, paresis, aphasia, stroke within prior 3 months, severe brain injuries, dementia, Parkinson’s disease, cerebellar disease, organic brain syndrome, uncontrolled mental illness or psychosis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11543853
The images show 1.66 nm-thick tomographic slices of rhinovirus 2-infected cos-7 cells seven to sixty minutes post-infection.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "images", "show", "1.66", "nm-thic...
PMC9429973
Nonhematologic grade 3/4 TEAEs in ≥2 patients included pneumonia (17%), lung infection (13%), and hyperglycemia (9%).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11774112
Then, H-His (Trt)-OH was added for the reaction, and TBDMS-polylactic acid-His (Trt)-OH was obtained after an overnight reaction.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "H-His", "...
PMC11703992
Gene Expression Omnibus (GEO) (http://www.ncbi.nlm.nih.gov/geo) was searched for datasets.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gene", "Expression", "Omnibus", "(", "GEO", ")", "(", "http://www.ncbi.nlm....
PMC9368503
There was no discernible pleomorphism.
[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "was", "no", "discernible", "pleomorphism", "." ] } ]
PMC11798926
For antibody feeding experiments, myc-SynDIG1-Flag transfected cells were incubated with α-Flag antibody at 37°C for 60 min.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "antibody", "feeding",...
PMC11739696
These nanoparticles exhibit high surface area-to-volume ratios and distinctive electronic properties, which make them suitable for various applications, including catalysis, energy storage, and biomedical uses.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10969097
The trial intended to investigate the combination of PSK (Krestin polysaccharide) treatment with docetaxel, a chemotherapy drug.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "trial", "intended", ...
PMC10667689
Further investigation is required, not only for all the questions that remained unanswered in our limited study (such as the probable role of TIM-3 in lipolysis in the HL-60 cell line, the role of TIM-3 in other aspects of glucose and lipid metabolism, or the effect of TIM-3 on other metabolic pathways), but also to clarify the effect of TIM-3 on the metabolism of other immune cells, other AML subtypes, and primary AML cells, as well as in a co-culture system with other cells (to recreate the bone marrow microenvironment and cellular interactions) and in vivo models and clinical studies.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7294030
Cells were stained with annexin V-FITC (recombinant annexin V protein conjugated to green fluorescent FITC dye) and PI for 10 - 15 min at room temperature in the dark.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11604768
Here, we leverage the experimental principles of these high throughput formats to create a powerful tool to easily quantify responses of synthetic promoters that serve as downstream transcriptional readouts of specific upstream signaling events in mammalian cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11786600
The results are expressed as mean ± standard deviation (n = 3).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", "are", "expressed", "as", "mean", "±", "standar...
PMC9429973
Compared with the non-T691s UL54 mutation, the patients with T691S mutation also had similar results.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Compared", "with", "the", "non-T691s", "UL54", "mutati...
PMC10745221
Additionally, human embryonic kidney 293T cells have multiple proteins with ADMA between 20kDa and 250 kDa, as well as three SDMA-containing proteins near 15 kDa, 20 kDa, and 30 kDa .
[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC9621239
Sn, Shannon entropy.
[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Sn", ",", "Shannon", "entropy", "." ] } ]
PMC8358006
Together, our results demonstrate that the biological nature of GSDs tend to be chromatin looping and relevance to the coordinately regulation of functionally related genes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10547921
Although NAMPT inhibitors are potent cytotoxic molecules, their use as chemotherapeutic drugs in cancer treatment is hampered by their toxicity.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Although", "NAMPT", ...
PMC11754094
b, Comparison of length bias according to type of DNA polymerase and PCR cycle.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "b", ",", "Comparison", "of", "length", "bias", "according",...
PMC11591038
It was demonstrated that the knockdown and overexpression of HIF-1α, respectively, reduced and increased neuroglobin levels, consistent with a causal relationship between HIF-1 and neuroglobin induction .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Median survival was 24 years and not reached for SVT+ and SVT-, respectively (p=0.1).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Median", "survival", "was", "24", "years", ...
PMC11754784
P < 0.0001.
[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "P", "<", "0.0001", "." ] } ]
PMC11760643
Conversely, numbers of non‐classical monocytes did not differ between both treatment groups (p = 0.14; Figure 4U).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Conversely", ",", ...