OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC10669966	Altogether, we identified 97 DEGs between the DDLPS subtype and the other two subtypes, 247 DEGs between the MLPS subtype and the other two subtypes, and 37 DEGs between the PLPS subtype and the other two subtypes, after using the IST-derived exclusion lists (see above).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11768927	VSV was one of the first viruses to be manipulated using reverse genetics, allowing the construction of recombinant VSV (rVSV) through targeted genome modifications .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11725127	Unfortunately, they have poor selectivity against USP2 because the catalytic domain is conserved among most USPs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Unfortunately", ",", "they", "have", "poor", ...
PMC9429973	Except for the T315I clone (B8, Table 1), other analysed clones expressed MCL-1 after exposure to BH3-mimetics.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Except", "for", "...
PMC11422497	Therefore, in our future work, further studies with larger groups of patients, the improvement of the circ_SMA4-miRNA-mRNA regulatory network, and further validation in vivo and in vitro also need to be explored.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11759543	The protein concentration was determined using the bicinchoninic acid assay (Thermo scientific, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "protein", "concentration", "was", "determined", ...
PMC11720808	Macroscopic image showing the collected tumor specimens after the mice were sacrificed. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Macroscopic", "image", "showing", "the", "collected", "tumor", "specimens", ...
PMC3730428	Consistent with FLIP downregulation being necessary for SAHA treatment to promote AT-IAP/TNFα-induced cell death, overexpression of either FLIP(S) or FLIP(L) blocked the effects of SAHA and AT-IAP/TNFα cotreatment on cell death (Figure 7b).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10142392	In addition, the relatively low melting temperatures of around 60 °C make PCL materials easy to manufacture or transform into highly structured forms .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11476106	We have modulated its stiffness to study a specific element of the tumor ECM, VN, opening the possibility of its use to study other proteins of interest and other tumor types.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11407042	Check the cell distribution under the inverted microscope.h.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Check", "the", "cell", "distribution", "under", "the", "inverted", "microscope.h", "." ] } ]
PMC9429973	Results: A 42 years-old male patient presented with B symptoms that lasted for 3 months.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "A", "42", "years-old", "male", "...
PMC9429973	Mean PoS decreased, and p50, 2,3-DPG level and ATP/2,3-DPG ratio significantly improved.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mean", "PoS", "decreased", ",", "and", "p50", ",", "2,3-DPG", ...
PMC11055443	Mesenchymal stem cell culture, secretome isolation, and characterization.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mesenchymal", "stem", "cell", "culture", ",", "secretome", "isolation", ",", "and", "characteriz...
PMC10968586	After ingestion, HT is more largely absorbed in the intestine by diffusion, is mainly metabolized into glucuronide and sulphate conjugates, and is excreted in urine mostly in its glucuronide conjugated form .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11656380	Cell viability of 100% was calculated by adding Hank’s balanced salt solution (HBBS) as a control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "viability", "of", ...
PMC11653533	Peiwu Geng: Writing – review & editing, Visualization, Software, Resources, Methodology, Investigation, Formal analysis, Data curation, Conceptualization.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10204952	The cells were cultured for 24 h for attachment before being treated with S1P for 48 h before staining.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cells", "were", "cultured"...
PMC11531744	Cross-validation for optimizing the parameter in LASSO regression. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cross-validation", "for", "optimizing", "the", "parameter", "in", "LASSO", "regression", ".", "(" ] }...
PMC11803149	The violin plot shows Epas1 expression in young and aged OT-I TCR-T cells. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "violin", "plot", "shows", "Epas1", "expression", "in", "y...
PMC6684588	For FST315-Fc, the SP Sepharose step was replaced by a preparative size-exclusion column, and the final material was dialyzed in phosphate-buffered saline.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	We used RT-PCR followed by direct sequencing to detect fusion genes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "used", "RT-PCR", "followed", "by", "direct", "sequencing", "to", "detect", "fus...
PMC9429973	T-Charge™ is a novel platform that retains the naive/Tscm immunophenotype of the input leukapheresis and reduces the manufacturing process time to <2 days.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC5417661	The IC50 concentrations of NOV202 were assessed in a panel of eight cancer cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "IC50", "concentrations", "of", "NOV202", "were", "as...
PMC11770199	Heatmap showed up-regulated apoptosis and pyroptosis-related genes. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Heatmap", "showed", "up-regulated", "apoptosis", "and", "pyroptosis-related", "genes", ".", "(" ] } ]
PMC11782508	cDNA synthesis was then performed using the ABT H-Minus cDNA Synthesis Kit (Applied Biotechnology, Egypt).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "cDNA", "synthesis", "was", "then", "pe...
PMC11395280	The TEER measurements made of our HBEC-5i monolayers, averaging 27.6 Ω × cm were characteristic of an intact monolayer, as were the presence of zonule occludins within the cell junctions (Figure 3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11344246	Furthermore, we only knocked down five of the top targets.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "we", "only", "knocked", "down", "five", "of", "the", "top", ...
PMC11588008	Previous literature shows that CTX and its metabolite phosphoramide mustard (PM) (Yuanye Shengwu, China) can cause cell damage.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Previou...
PMC10849234	For each panel, the data are averages of three independent experiments performed in triplicate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "each", "panel", ",", "the", "data", "are", "av...
PMC11592837	Following this argument, it seems unlikely to us because incubation with 1 µM DOX, but not with 25 µM ETP, caused peak phosphorylation of H2AX in dose dependent experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	A subset of patients happened to high-grade transformation (HT) to the more aggressive diffuse large B cell lymphoma (DLBCL), associated with inferior clinical outcomes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10565698	RNA immunoprecipitation and dual-luciferase reporter assays were performed to study the mechanistic relationship between circUSP10, miR-211-5p, and transcription factor 12 (TCF12).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10568263	The size of the nanoflowers increased to 250–270 nm due to the addition of PVP surfactant, while the size of the Au NPs was approximately 15–20 nm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11545868	The basic structure of flavonoids, which are double polyphenolic compounds, consists of 15 carbons, two aromatic rings, and one pyran ring, and flavonoids are classified into various subgroups based on changes in the carbon structure of each ring and the degree of oxidation or unsaturation, including flavone, flavonol, isoflavone, anthocyanidin, flavanone, and flavan-3-ol (Figure 2) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10748106	In Table 9, the descriptors of these ten designed ligands are presented.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "Table", "9", ",", "the", "descriptors", "of", "these", "ten", ...
PMC5574817	Standard curve plots for amplification efficiency of hERG and β-actin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Standard", "curve", "plots", "for", "amplification", "efficiency", "of", "hERG", "and", "β-actin...
PMC11536589	Representative images were shown here and other images were represented in Supplementary Fig. 5D. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Representative", "images", "were", "shown", "here", "and", ...
PMC10719213	DNA was extracted using QIAamp DNA Mini Kit (Qiagen).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "DNA", "was", "extracted", "using", "QIAamp", "DNA", "Mini", "Kit", "(", "Qiagen", ...
PMC11552389	The impact of FOXN3 on drug IC50 values. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "impact", "of", "FOXN3", "on", "drug", "IC50", "values", ".", "(" ] } ]
PMC11200978	A single 5 min freeze to −10 °C or −15 °C yielded minimal cell death at 24 h post freeze (−10 °C: 164.5% (±1.2) and −15 °C: 96.4% (±2.8), versus control 137.9% (±0.8), respectively).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7351993	It is important to note that the RIACS can accept any image feature such as perimeter, circularity, and chemical localization as long as the total signal processing time fits within the sort latency.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10899471	In this study, we demonstrated that the expression of BATF2 was downregulated in human sarcoma tissues and cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this", "study", ...
PMC10808409	It has been reported that using individual Pluronic might not be effective in achieving both high micellar dispersion stability and high encapsulation efficiency of poorly soluble drugs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7053076	Here, we have shown that in leukemic HL-60/5FU cells the levels of only three out of 5 NF-κB subunits were affected by BGD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "token...
PMC9429973	Interestingly, we found a significant decrease in levels of iNKT PD-1+ cells after mRNA vaccination in CLL patients in short-term (median: 50% vs 65.22%, P<.05) as well as in long-term response (median: 46.67% vs 66.67%, P<.03, compared to baseline in paired samples.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2118063	As a third approach to understanding genes regulated by IRF8 in B cells, we examined mice homozygous for a null mutation of the gene (−/−) or WT animals (+/+) (12).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11489351	Of the 193 genes reported in the Putney microarray dataset, 73 (37.8%) were also found in the RNA-seq dataset of low pHi compared to control (Fig. S3A and Table S4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11683240	E–G, The 488-labeled PT (500 ng/ml) and different concentrations of α1AT or the respective amount of solvent (H2O) were preincubated for 15 min at room temperature before addition to CHO-K1 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2777936	Other studies looking at POU5F1 target genes in human and mouse ES cells proposed that PORCN, FRAT2, and FZD5 were potential POU5F1 target genes .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11190538	The increasing pH on day 21 was most likely due to the formation of metabolites such as amino acids, bacteriocins, and vitamins as the shelf life ended.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612626	Treatment with most compounds at 1 μmol/L for 48 hours maximally increased LLVY-R110 cleavage and maintained cell viability >90%.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Treatment", "with", ...
PMC9512971	LE last evaluation RRT renal replacement therapy, ECMO extracorporeal membrane oxygenation The median time to resolution of clinical symptoms was 13 days in the camostat mesilate and 12 days in the placebo group (Table 2).Table 2Time to resolution of clinical symptomsCamostat mesilate (N = 53)Placebo (N = 52)Events, n (%)23 (43.4)23 (44.2)Median (95% CI) (days)13.0 (10.0–n/c)12.0 (10.0–n/c)25th to 75th percentile7.0–15.09.0–n/cRange2–16 + 2–14 + + censored, CI confidence interval, n/c not calculable Time to resolution of clinical symptoms + censored, CI confidence interval, n/c not calculable Adverse events occurred in 25 of 77 patients in the camostat mesilate group (32.5%) and in 31 of 76 patients in the placebo group (40.8%) (Table 3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9646302	All data are presented as means± standard deviations and were statistically analyzed using SPSS software (version 23.0; IBM Corp., Armonk, NY, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10196713	Accumulating evidence has revealed that resistance to copper-dependent cell death; namely, cuproptosis, is also important for the progression of carcinomas (30,31).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11779960	Nearly all TCLs express TCRαβ on the cell surface, thus TRBC1/TRBC2 targeting is an attractive therapeutic strategy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Nearly", "all", "TCLs", "express", "TC...
PMC9792775	Therefore, it is expected to be a means to deliver targeted drugs to cancer patients and intensify treatment at specific sites.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ...
PMC10196713	The following ovarian endometrioid carcinoma cell lines were obtained: the A2780 cell line (parental cells) and the A2780cis cell line (29).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "...
PMC9429973	Median survival was 21 months in females as compared to 16 months in males (p = 0.04).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Median", "survival", "was", "21",...
PMC10669966	No. HY-145924, MedChemExpress, Monmouth Junction, NJ, USA), cilostazol (CAS No. 73963-72-1, Cat.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11352666	MERTK and TYRO3 are stimulated by all three ligands, but AXL is only stimulated by GAS6 .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MERTK", "and", "TYRO3", "are", "stimulated", ...
PMC11676670	Using the xCELLigence system, we observed that the OVAR79 cells demonstrate a higher biomass accumulation rate compared to the widely used ovarian cancer cell lines SKOV3 and OVCAR3 (Figure 1C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9780037	Released cyt c triggers apoptosis of the cell.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Released", "cyt", "c", "triggers", "apoptosis", "of", "the", "cell", "." ] } ]
PMC9429973	We also found UCK2 gene expression was upregulated via activation of T-cell receptor (TCR) signaling pathway in normal CD4+ T-cells (Fig. B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11750165	These observations indicate that the NTD of zebrafish PEX1 might interact with zebrafish Jagged2 through its ICD. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "observations", "indicate", "that", ...
PMC11306019	Nonetheless, at approximately 3 nM, BTZ does not exhibit noticeable toxicity in standard cytotoxicity assays.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Nonetheless", ",", "at", "approximately", "3", ...
PMC9429973	Dose escalation, with limited treatment options in the ≥3-line setting, ASC4OPT will explore whether pts not in major molecular response (MMR) at ≥48 weeks (wks) could benefit from a potential dose escalation to 200 mg QD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11745823	Oxygen is the first element of human life, and the balance of oxygen concentration in the internal environment is a necessary condition for the body to carry out normal aerobic metabolism .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8010066	Therefore, it is suggested that in future studies, the nutritional status of the cell be taken into account when evaluating QS-based gene expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11033180	Therefore, the S956G mutation could limit Sema5A’s ability to interact with component of the extracellular matrix or other binding partners yet to be characterized.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7812570	To verify whether the fusion genes were expressed on the cell surface through the GPI anchor, transduced TZM-bl cells were treated with phosphatidylinositol-specific phospholipase C (PI-PLC) and then stained with an anti-His tag antibody, followed by FACS analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8345486	Their activity profile indicates that they are possible boron-carrier chemotherapeutics suitable for boron neutron capture therapy .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Their", "activity", "profile", "indicates", "that", "t...
PMC9219615	In this experiment, cells in the early stages of apoptosis were distinguished by their emission of FITC signal.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this", "experiment", ",", ...
PMC10577955	The third compound BA was obtained by using n-hexane-ethyl acetate (8:2 v/v) where its H-NMR and C-NMR data were identical to those reported for betulinic acid .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11269792	Knockdown of circAPP inhibits GIST proliferation and the Warburg effect.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Knockdown", "of", "circAPP", "inhibits", "GIST", "proliferation", "and", "the", "Warburg", "effe...
PMC11701801	The SWI/SNF complex plays a vital role in regulating cellular functions such as transcription by modulating the chromatin structure via regulating genes related to various chromatin-regulating factors (3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6617630	These results indicate that MYC and BCL6 (but not BCL2) are regulated by BET bromodomain and can be potentially targeted by BET inhibitors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11335267	Data represent mean ± SEM. *	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "represent", "mean", "±", "SEM", ".", "*" ] } ]
PMC10523483	Differentially expressed genes in GSE19188 (T, LUAD, n = 45; N, normal adjacent lung tissues, n = 65). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11679326	O-glycosylation occurs in the Golgi apparatus and begins with the addition of N-acetylgalactosamine to serine or threonine residues in the target protein (Figure 1g).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4270159	MCF7: pHER3.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "MCF7", ":", "pHER3", "." ] } ]
PMC6600253	Upregulation of the p53-CXCR2 axis is largely responsible for RSV-induced senescence.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Upregulation", "of", "the", "p53-CXCR2", "axis", "is", "largely", "responsible", "for", ...
PMC11770130	ICV injection or local ablation of ceramide C6 in hypothalamus of mice may either increase food intake or have no effects on food intake.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9250505	NPB treatment of PDO1 cells significantly decreased levels of pBADS99 compared to vehicle-treated cells (normalized to BAD expression).	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "NPB", "treatment", ...
PMC10958426	In conclusion, we characterized the features of cancer cells in tumor tissues by comparing with their counterparts in normal tissues at single cell resolution.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC6889484	Averages of two independent infections are indicated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Averages", "of", "two", "independent", "infections", "are", "indicated", "." ] } ]
PMC11705862	Quantifications are shown in (L and N).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Quantifications", "are", "shown", "in", "(", "L", "and", "N", ")", "." ] } ]
PMC11437637	The above reference values were provided by the clinical laboratory department of our hospital.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "above", "reference", "values", "were", "provided", "by", ...
PMC8633974	RT-qPCR was performed in technical triplicates using standard curve absolute quantitation for gapdh (1 diploid for genome = 6.6 picograms DNA extracted from ACH2 cells) and spCas9 (pLenti-CRISPR-RFP657; 10 copies equal 12.01 ng according to MW 7.22 x 10 Da).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11271278	This approach identified known and novel enhancer hijacking events, prioritized their target genes, and defined the underlying enhancers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "approach", "identifi...
PMC11633763	Genetic anomalies in HK significantly affect the development and progression of several clinical diseases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Genetic", "anomalies", "in", "HK", "significantly", "affect", "the", ...
PMC8996378	By SAR studies, it was concluded that the presence of an aromatic component on the lathyrane scaffold significantly improved the inhibition of Rh123 efflux (Reis et al., 2020).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11366496	Despite the ongoing advancements in extensive treatments, including surgical interventions, radiotherapy, chemotherapy, and tumor treating fields technology (TTFields), the GBM survival period only increased from 14 months to about 20 months. ,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5673060	Long-term colony formation assays show that low dose NVP-AUY-922 (5 nM) is capable of not only sensitizing both PazR and DasR cells but also killing parental A204 cells (Fig. 7D and E), suggesting that HSP90 inhibitors may be an effective option both as first-line and salvage therapy in rhabdoid tumours.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "...
PMC11789597	Widely used and FDA‐approved cholesterol‐depleting drugs, lovastatin and simvastatin, have been proven to efficiently modulate CAV1 through the depletion of membrane cholesterol. ,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11656657	Peripheral blood mononuclear cells (PBMCs) were isolated from buffy-coats obtained from healthy donors (Bambino Gesù Children’s Hospital, Rome, Italy) who signed a written informed consent, in accordance with rules set by the Institutional Review Board of OPBG (Approval of Ethical Committee N°969/2015 prot.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11767793	Gold nanoparticles can interfere with various assays due to their optical properties and chemical interactions with test reagents ; therefore, a careful analysis and/or control of such interferences should be included in the measurement procedure.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11335267	Santa Cruz Biotechnology) were injected.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Santa", "Cruz", "Biotechnology", ")", "were", "injected", "." ] } ]
PMC11721295	Interestingly, characteristics of the microenvironment, such as fibroblast activation status, drastically changed upon KRAS inactivation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interestingly", ",", "characteristics", "of"...
PMC10748106	Five CFDs were selected in Genipin as they were common with the other four simple iridoids (Euphrasin, Campsinol, Artselaenin A, and Artselaenin B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10669966

Altogether, we identified 97 DEGs between the DDLPS subtype and the other two subtypes, 247 DEGs between the MLPS subtype and the other two subtypes, and 37 DEGs between the PLPS subtype and the other two subtypes, after using the IST-derived exclusion lists (see above).

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PMC11768927

VSV was one of the first viruses to be manipulated using reverse genetics, allowing the construction of recombinant VSV (rVSV) through targeted genome modifications .

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PMC11725127

Unfortunately, they have poor selectivity against USP2 because the catalytic domain is conserved among most USPs.

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PMC9429973

Except for the T315I clone (B8, Table 1), other analysed clones expressed MCL-1 after exposure to BH3-mimetics.

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PMC11422497

Therefore, in our future work, further studies with larger groups of patients, the improvement of the circ_SMA4-miRNA-mRNA regulatory network, and further validation in vivo and in vitro also need to be explored.

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PMC11759543

The protein concentration was determined using the bicinchoninic acid assay (Thermo scientific, USA).

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PMC11720808

Macroscopic image showing the collected tumor specimens after the mice were sacrificed. (

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PMC3730428

Consistent with FLIP downregulation being necessary for SAHA treatment to promote AT-IAP/TNFα-induced cell death, overexpression of either FLIP(S) or FLIP(L) blocked the effects of SAHA and AT-IAP/TNFα cotreatment on cell death (Figure 7b).

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PMC10142392

In addition, the relatively low melting temperatures of around 60 °C make PCL materials easy to manufacture or transform into highly structured forms .

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PMC11476106

We have modulated its stiffness to study a specific element of the tumor ECM, VN, opening the possibility of its use to study other proteins of interest and other tumor types.

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PMC11407042

Check the cell distribution under the inverted microscope.h.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Check", "the", "cell", "distribution", "under", "the", "inverted", "microscope.h", "." ] } ]

PMC9429973

Results: A 42 years-old male patient presented with B symptoms that lasted for 3 months.

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PMC9429973

Mean PoS decreased, and p50, 2,3-DPG level and ATP/2,3-DPG ratio significantly improved.

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PMC11055443

Mesenchymal stem cell culture, secretome isolation, and characterization.

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PMC10968586

After ingestion, HT is more largely absorbed in the intestine by diffusion, is mainly metabolized into glucuronide and sulphate conjugates, and is excreted in urine mostly in its glucuronide conjugated form .

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PMC11656380

Cell viability of 100% was calculated by adding Hank’s balanced salt solution (HBBS) as a control.

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PMC11653533

Peiwu Geng: Writing – review & editing, Visualization, Software, Resources, Methodology, Investigation, Formal analysis, Data curation, Conceptualization.

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PMC10204952

The cells were cultured for 24 h for attachment before being treated with S1P for 48 h before staining.

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PMC11531744

Cross-validation for optimizing the parameter in LASSO regression. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cross-validation", "for", "optimizing", "the", "parameter", "in", "LASSO", "regression", ".", "(" ] }...

PMC11803149

The violin plot shows Epas1 expression in young and aged OT-I TCR-T cells. (

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PMC6684588

For FST315-Fc, the SP Sepharose step was replaced by a preparative size-exclusion column, and the final material was dialyzed in phosphate-buffered saline.

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PMC9429973

We used RT-PCR followed by direct sequencing to detect fusion genes.

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PMC9429973

T-Charge™ is a novel platform that retains the naive/Tscm immunophenotype of the input leukapheresis and reduces the manufacturing process time to <2 days.

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PMC5417661

The IC50 concentrations of NOV202 were assessed in a panel of eight cancer cell lines.

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PMC11770199

Heatmap showed up-regulated apoptosis and pyroptosis-related genes. (

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PMC11782508

cDNA synthesis was then performed using the ABT H-Minus cDNA Synthesis Kit (Applied Biotechnology, Egypt).

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PMC11395280

The TEER measurements made of our HBEC-5i monolayers, averaging 27.6 Ω × cm were characteristic of an intact monolayer, as were the presence of zonule occludins within the cell junctions (Figure 3).

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PMC11344246

Furthermore, we only knocked down five of the top targets.

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PMC11588008

Previous literature shows that CTX and its metabolite phosphoramide mustard (PM) (Yuanye Shengwu, China) can cause cell damage.

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PMC10849234

For each panel, the data are averages of three independent experiments performed in triplicate.

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PMC11592837

Following this argument, it seems unlikely to us because incubation with 1 µM DOX, but not with 25 µM ETP, caused peak phosphorylation of H2AX in dose dependent experiments.

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PMC9429973

A subset of patients happened to high-grade transformation (HT) to the more aggressive diffuse large B cell lymphoma (DLBCL), associated with inferior clinical outcomes.

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PMC10565698

RNA immunoprecipitation and dual-luciferase reporter assays were performed to study the mechanistic relationship between circUSP10, miR-211-5p, and transcription factor 12 (TCF12).

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PMC10568263

The size of the nanoflowers increased to 250–270 nm due to the addition of PVP surfactant, while the size of the Au NPs was approximately 15–20 nm.

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PMC11545868

The basic structure of flavonoids, which are double polyphenolic compounds, consists of 15 carbons, two aromatic rings, and one pyran ring, and flavonoids are classified into various subgroups based on changes in the carbon structure of each ring and the degree of oxidation or unsaturation, including flavone, flavonol, isoflavone, anthocyanidin, flavanone, and flavan-3-ol (Figure 2) .

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PMC10748106

In Table 9, the descriptors of these ten designed ligands are presented.

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PMC5574817

Standard curve plots for amplification efficiency of hERG and β-actin.

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PMC11536589

Representative images were shown here and other images were represented in Supplementary Fig. 5D. (

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PMC10719213

DNA was extracted using QIAamp DNA Mini Kit (Qiagen).

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PMC11552389

The impact of FOXN3 on drug IC50 values. (

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PMC11200978

A single 5 min freeze to −10 °C or −15 °C yielded minimal cell death at 24 h post freeze (−10 °C: 164.5% (±1.2) and −15 °C: 96.4% (±2.8), versus control 137.9% (±0.8), respectively).

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PMC7351993

It is important to note that the RIACS can accept any image feature such as perimeter, circularity, and chemical localization as long as the total signal processing time fits within the sort latency.

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PMC10899471

In this study, we demonstrated that the expression of BATF2 was downregulated in human sarcoma tissues and cell lines.

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PMC10808409

It has been reported that using individual Pluronic might not be effective in achieving both high micellar dispersion stability and high encapsulation efficiency of poorly soluble drugs.

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PMC7053076

Here, we have shown that in leukemic HL-60/5FU cells the levels of only three out of 5 NF-κB subunits were affected by BGD.

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PMC9429973

Interestingly, we found a significant decrease in levels of iNKT PD-1+ cells after mRNA vaccination in CLL patients in short-term (median: 50% vs 65.22%, P<.05) as well as in long-term response (median: 46.67% vs 66.67%, P<.03, compared to baseline in paired samples.

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PMC2118063

As a third approach to understanding genes regulated by IRF8 in B cells, we examined mice homozygous for a null mutation of the gene (−/−) or WT animals (+/+) (12).

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PMC11489351

Of the 193 genes reported in the Putney microarray dataset, 73 (37.8%) were also found in the RNA-seq dataset of low pHi compared to control (Fig. S3A and Table S4).

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PMC11683240

E–G, The 488-labeled PT (500 ng/ml) and different concentrations of α1AT or the respective amount of solvent (H2O) were preincubated for 15 min at room temperature before addition to CHO-K1 cells.

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PMC2777936

Other studies looking at POU5F1 target genes in human and mouse ES cells proposed that PORCN, FRAT2, and FZD5 were potential POU5F1 target genes .

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PMC11190538

The increasing pH on day 21 was most likely due to the formation of metabolites such as amino acids, bacteriocins, and vitamins as the shelf life ended.

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PMC11612626

Treatment with most compounds at 1 μmol/L for 48 hours maximally increased LLVY-R110 cleavage and maintained cell viability >90%.

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PMC9512971

LE last evaluation RRT renal replacement therapy, ECMO extracorporeal membrane oxygenation The median time to resolution of clinical symptoms was 13 days in the camostat mesilate and 12 days in the placebo group (Table 2).Table 2Time to resolution of clinical symptomsCamostat mesilate (N = 53)Placebo (N = 52)Events, n (%)23 (43.4)23 (44.2)Median (95% CI) (days)13.0 (10.0–n/c)12.0 (10.0–n/c)25th to 75th percentile7.0–15.09.0–n/cRange2–16 + 2–14 + + censored, CI confidence interval, n/c not calculable Time to resolution of clinical symptoms + censored, CI confidence interval, n/c not calculable Adverse events occurred in 25 of 77 patients in the camostat mesilate group (32.5%) and in 31 of 76 patients in the placebo group (40.8%) (Table 3).

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PMC9646302

All data are presented as means± standard deviations and were statistically analyzed using SPSS software (version 23.0; IBM Corp., Armonk, NY, USA).

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PMC10196713

Accumulating evidence has revealed that resistance to copper-dependent cell death; namely, cuproptosis, is also important for the progression of carcinomas (30,31).

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PMC11779960

Nearly all TCLs express TCRαβ on the cell surface, thus TRBC1/TRBC2 targeting is an attractive therapeutic strategy.

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PMC9792775

Therefore, it is expected to be a means to deliver targeted drugs to cancer patients and intensify treatment at specific sites.

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PMC10196713

The following ovarian endometrioid carcinoma cell lines were obtained: the A2780 cell line (parental cells) and the A2780cis cell line (29).

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PMC9429973

Median survival was 21 months in females as compared to 16 months in males (p = 0.04).

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PMC10669966

No. HY-145924, MedChemExpress, Monmouth Junction, NJ, USA), cilostazol (CAS No. 73963-72-1, Cat.

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PMC11352666

MERTK and TYRO3 are stimulated by all three ligands, but AXL is only stimulated by GAS6 .

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PMC11676670

Using the xCELLigence system, we observed that the OVAR79 cells demonstrate a higher biomass accumulation rate compared to the widely used ovarian cancer cell lines SKOV3 and OVCAR3 (Figure 1C).

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PMC9780037

Released cyt c triggers apoptosis of the cell.

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PMC9429973

We also found UCK2 gene expression was upregulated via activation of T-cell receptor (TCR) signaling pathway in normal CD4+ T-cells (Fig. B).

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PMC11750165

These observations indicate that the NTD of zebrafish PEX1 might interact with zebrafish Jagged2 through its ICD. (

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PMC11306019

Nonetheless, at approximately 3 nM, BTZ does not exhibit noticeable toxicity in standard cytotoxicity assays.

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PMC9429973

Dose escalation, with limited treatment options in the ≥3-line setting, ASC4OPT will explore whether pts not in major molecular response (MMR) at ≥48 weeks (wks) could benefit from a potential dose escalation to 200 mg QD.

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PMC11745823

Oxygen is the first element of human life, and the balance of oxygen concentration in the internal environment is a necessary condition for the body to carry out normal aerobic metabolism .

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PMC8010066

Therefore, it is suggested that in future studies, the nutritional status of the cell be taken into account when evaluating QS-based gene expression.

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PMC11033180

Therefore, the S956G mutation could limit Sema5A’s ability to interact with component of the extracellular matrix or other binding partners yet to be characterized.

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PMC7812570

To verify whether the fusion genes were expressed on the cell surface through the GPI anchor, transduced TZM-bl cells were treated with phosphatidylinositol-specific phospholipase C (PI-PLC) and then stained with an anti-His tag antibody, followed by FACS analysis.

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PMC8345486

Their activity profile indicates that they are possible boron-carrier chemotherapeutics suitable for boron neutron capture therapy .

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PMC9219615

In this experiment, cells in the early stages of apoptosis were distinguished by their emission of FITC signal.

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PMC10577955

The third compound BA was obtained by using n-hexane-ethyl acetate (8:2 v/v) where its H-NMR and C-NMR data were identical to those reported for betulinic acid .

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PMC11269792

Knockdown of circAPP inhibits GIST proliferation and the Warburg effect.

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PMC11701801

The SWI/SNF complex plays a vital role in regulating cellular functions such as transcription by modulating the chromatin structure via regulating genes related to various chromatin-regulating factors (3).

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PMC6617630

These results indicate that MYC and BCL6 (but not BCL2) are regulated by BET bromodomain and can be potentially targeted by BET inhibitors.

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PMC11335267

Data represent mean ± SEM. *

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PMC10523483

Differentially expressed genes in GSE19188 (T, LUAD, n = 45; N, normal adjacent lung tissues, n = 65). (

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PMC11679326

O-glycosylation occurs in the Golgi apparatus and begins with the addition of N-acetylgalactosamine to serine or threonine residues in the target protein (Figure 1g).

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PMC4270159

MCF7: pHER3.

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PMC6600253

Upregulation of the p53-CXCR2 axis is largely responsible for RSV-induced senescence.

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PMC11770130

ICV injection or local ablation of ceramide C6 in hypothalamus of mice may either increase food intake or have no effects on food intake.

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PMC9250505

NPB treatment of PDO1 cells significantly decreased levels of pBADS99 compared to vehicle-treated cells (normalized to BAD expression).

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PMC10958426

In conclusion, we characterized the features of cancer cells in tumor tissues by comparing with their counterparts in normal tissues at single cell resolution.

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PMC6889484

Averages of two independent infections are indicated.

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PMC11705862

Quantifications are shown in (L and N).

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PMC11437637

The above reference values were provided by the clinical laboratory department of our hospital.

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PMC8633974

RT-qPCR was performed in technical triplicates using standard curve absolute quantitation for gapdh (1 diploid for genome = 6.6 picograms DNA extracted from ACH2 cells) and spCas9 (pLenti-CRISPR-RFP657; 10 copies equal 12.01 ng according to MW 7.22 x 10 Da).

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PMC11271278

This approach identified known and novel enhancer hijacking events, prioritized their target genes, and defined the underlying enhancers.

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PMC11633763

Genetic anomalies in HK significantly affect the development and progression of several clinical diseases.

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PMC8996378

By SAR studies, it was concluded that the presence of an aromatic component on the lathyrane scaffold significantly improved the inhibition of Rh123 efflux (Reis et al., 2020).

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PMC11366496

Despite the ongoing advancements in extensive treatments, including surgical interventions, radiotherapy, chemotherapy, and tumor treating fields technology (TTFields), the GBM survival period only increased from 14 months to about 20 months. ,

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PMC5673060

Long-term colony formation assays show that low dose NVP-AUY-922 (5 nM) is capable of not only sensitizing both PazR and DasR cells but also killing parental A204 cells (Fig. 7D and E), suggesting that HSP90 inhibitors may be an effective option both as first-line and salvage therapy in rhabdoid tumours.

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PMC11789597

Widely used and FDA‐approved cholesterol‐depleting drugs, lovastatin and simvastatin, have been proven to efficiently modulate CAV1 through the depletion of membrane cholesterol. ,

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PMC11656657

Peripheral blood mononuclear cells (PBMCs) were isolated from buffy-coats obtained from healthy donors (Bambino Gesù Children’s Hospital, Rome, Italy) who signed a written informed consent, in accordance with rules set by the Institutional Review Board of OPBG (Approval of Ethical Committee N°969/2015 prot.

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PMC11767793

Gold nanoparticles can interfere with various assays due to their optical properties and chemical interactions with test reagents ; therefore, a careful analysis and/or control of such interferences should be included in the measurement procedure.

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PMC11335267

Santa Cruz Biotechnology) were injected.

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PMC11721295

Interestingly, characteristics of the microenvironment, such as fibroblast activation status, drastically changed upon KRAS inactivation.

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PMC10748106

Five CFDs were selected in Genipin as they were common with the other four simple iridoids (Euphrasin, Campsinol, Artselaenin A, and Artselaenin B).

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