OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC11087766	Infections were incubated rotating at 30 °C and then inoculated on 1% agarose pads containing 25% LB and 1 µg/mL DAPI and dried for 5 min at room temperature before a coverslip was applied.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7348793	Shorter NUMTs can not be amplified with our long-range primers), (b) our primers should have sufficient homology to NUMTs, and (c) the breaking point for NUMT insertion should have occurred within the short 777 bp region between our primers for long-range amplification, which is unlikely.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11345828	The combined organic layers were washed with sat.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "combined", "organic", "layers", "were", "washed", "with", "sat", "." ] } ]
PMC9429973	Comparatively, OS was longer with RUX vs PBO/BAT regardless of disease duration.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Comparatively", ",", "OS", "was", "longer", "with", "RUX", "vs", "PBO...
PMC10587429	Return the mice to their microisolator cages, provide proper food and water and wait for 24 hours before injecting the CD34 HSCs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Return"...
PMC10454535	One-way analysis of variance and Dunnett’s multiple comparisons tests were run using GraphPad Prism 9.3.1 software (GraphPad Software, Inc., San Diego, CA, USA) to determine statistical significance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10698968	Erythrosine B stain was used to discriminate and count viable cells through Countess™ II FL Cell Counter (Life Technologies).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Erythrosine", ...
PMC9429973	Median age at ponatinib start was 61 years for CML and 56 years for Ph+ALL patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Median", "age", "at", "ponatinib", "start", "was", ...
PMC11300639	k 786-O and A498 cells were transfected with indicates plasmids for 48 h. Cells were harvested for CCK-8, transwell and tube formation assay.	[ { "tags": [ "B-CellLine", "I-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC11772585	K The protein levels of METTL1 and ATF4 in normal specimens (n = 7) and cSCC tumors (n = 36) with different tumor grade were detected by IHC on continuous sections.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4005030	Also this is a folk remedy for abscesses, bilious conditions, cancer, cough, debility, dyspepsia, dysuria, fever, hangover, heart ailments, hypertension , neurosis, scurvy, and strangury.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11543885	For western blot analysis, use 12 μL of the whole cell lysate and 15 μL of the eluted biotinylated proteins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "western", ...
PMC9429973	All calculations were made in SPSS program version 26.0.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "calculations", "were", "made", "in", "SPSS", "program", "version", "26.0", "." ] } ]
PMC11607321	This reduces the number of trainable parameters by 39.2% while maintaining low reconstruction error.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "reduces", "the", "number", "of", "trainable", "para...
PMC7602170	Until recently, KIT (CD117), a tyrosine kinase receptor, has been the main tool for the validation of GISTs with a positivity rate in immunohistochemistry of more than 90% (Table 1) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11657695	D Gene expression (Log2 normalized expression) of KCNA2 in Mesenchymal Stem Cells (MSCs) coming from thirty healthy donors (30 donors) and in Ewing sarcoma patients (117 patients) (Mann–Whitney test).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Josip Benčević, Slavonski Brod; School of Medicine, University of Osijek Josip Juraj Strossmayer, Osijek; Internal medicine department, General Hospital dr.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11755519	What brings more attention and potential implications is the fact that cancer cells secrete more EVs than non-malignant cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "What", "brings", "more", "attenti...
PMC11802855	A The optimal cut-off value of the relative expression level of CXCL7.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "The", "optimal", "cut-off", "value", "of", "the", "relative", "expression",...
PMC6133382	Serial dilutions of monoclonal antibodies were added in a range from 10 μg/mL to 0.0001 μg/mL and then incubated at 25 °C for 90 minutes with shaking.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11401358	However, it is difficult to test the antioxidant mechanism with intact SF because SF has a large molecular weight of over 5000 amino acids.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11400680	Based on the comparative results, he proved that U-Net+ consumes a fewer number of weights, and shorter inference time while providing more accurate segmentations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11592837	Contrarily, analyzing the same time series in all samples, the Alu index tended to increase moderately until 4 h, with control cells starting at 0.72 and reaching a maximum of 1.1, but then tailing off to 0.73 (Figure 7D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11377827	Each dot represents the mean fluorescence intensity (AU at 488 nm) of a biological replicate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "dot", "represents", "the", "mean", ...
PMC5810978	A single genotype, genogroup I and genotype 2 (GI.2), was predominantly detected from acute non-bacterial gastroenteritis outbreaks throughout Japan in 2012 and 2013 .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10094992	Statistical evaluation of the differential analyses was performed by one-way ANOVA and Student’s t-test.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "evaluation", "of", "the", "differential", "analyse...
PMC9429973	Thrombomodulin, among other factors, plays a key role as an anticoagulant factor through activation of protein C and subsequent limitation of thrombin generation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11420784	n = 3 slides.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "n", "=", "3", "slides", "." ] } ]
PMC11680049	Previously, when studying the localization of polyphenols in plant tissues, researchers in many cases noted the accumulation of flavonoids mainly in the epidermal layers of leaves .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11740399	The mice were intraperitoneally injected with 50 mg/kg 3025@ML every day and 10 mg/kg OXA once a week.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mice", "were", "intraperitoneally", ...
PMC7762347	Nevertheless, additional studies are needed to completely understand its genotoxic properties.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Nevertheless", ",", "additional", "studies", "are", "needed", "to", "completely", ...
PMC11095939	Because of the limited number of cKO animals, we could only assess the effects at 6 hr post-PHx.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Because", "of", "the", "limited",...
PMC11788920	Schematic of the DNA construct and CRISPR–dCas9 target sites 1–4 on the template and NTSs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Schematic", "of", "the", "DNA", "construct", ...
PMC9985266	Pathological phenomena were observed, such as a thickened alveolar septum, infiltrating inflammatory cells, and a large number of collapsed alveoli, and the degree of PF became more severe with increasing induction time (Additional file 1: Fig. S1A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11697703	MAPK8 is required for netrin-1 signaling through DCC (DCC Netrin 1 receptor), which is required during callosal projection guidance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MAPK8", "is"...
PMC11489275	The lowest tertile of lymphocytes group as reference, the risk of death within 1 month in the middle and the highest tertile group was 0.745 times (95% CI 0.416–1.336) and 0.497 times (95% CI 0.260–0.949), respectively (Fig. 1C, D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6617630	In summary, we identified an in vitro model for DHL/THL DLBCLs and provide evidence for the therapeutic potential of BET inhibitor alone or in combination with BCL2 inhibitor.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	We previously demonstrated that leukemia-derived sEV are involved in the re-education of surrounding cells and increased immune escape.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "previously", "demonstrated", "that", ...
PMC11209164	The spread of the virus was also evaluated using a plaque assay designed to measure plaque size, revealing that TPF significantly increased the area of viral plaques within a monolayer of the 786-0 cells, as determined by Coomassie blue staining as shown in (Figure 1G).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11106977	Osteoblasts, which are bone-forming cells, play a crucial role in the modeling and remodeling of bones.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Osteoblasts", ",", "which", "are", "bo...
PMC11672881	The integration of DEGs with the heatmap and GO analyses provides a comprehensive view of how TQ, CU, and their combination impact A375 cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", ...
PMC9429973	Patients were randomized 1:1 to either Sequence A: DEC-C (35 mg DEC/100 mg cedazuridine) in Cycle 1 followed by IV-DEC at 20 mg/m in Cycle 2, or Sequence B: receiving IV-DEC in Cycle 1 followed by DEC-C on Cycle 2 to compare PK [primary endpoint Area Under the Curve (AUC) equivalence over 5 days of dosing].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7887261	Oncoarray case–control study (17,878 LCs vs. 13,425 controls; dbGaP phs001273): The OncoArray consortium is a network created to increase understanding of the genetic architecture of common cancers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10898159	SH3BP2 promotes the expression of mutant KIT via up-regulation of the expression of microphthalmia-associated transcription factors (MITF) and ETV1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SH3BP2", "promotes", ...
PMC10976516	Rincón et al. used the syngeneic murine CMT64 lung cancer cell line to produce a human adenovirus semi-permissive tumor model.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Rincón", "et", "al....
PMC10813895	Although loss of fidelity with age is observed in both lineages, it is most pronounced in luminal epithelial cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Although", "loss", "of", ...
PMC11033180	Moreover, the reduced level of synapsin 1 phosphorylation at Ser603 was not observed in neurons cocultured with COS cells expressing Sema5A-Fc-S956G (Figure 7D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", ...
PMC8658661	However, even after the publication of such articles, researchers continue to call the genesis of the cell line differently.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "e...
PMC4695073	IC50 values of cisplatin were measured by MTT assay after knocking down XPA expression in NPC cell line HONE1 and CNE1 cells by transient transfection of siRNAs (NC-si as negative control) for 24 h. A., B. Representative dose-dependent cell viability curves in HONE1 and CNE1 cells (inner, Western blotting for XPA expression).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "...
PMC10728200	Furthermore, STUB1 overexpression significantly increased GPX4 ubiquitination (Fig. 4E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "STUB1", "overexpression", "significantly", "increased", "GPX4", "u...
PMC10976516	Patel et al. (Table 2) used ex-vivo-infected BOECs to deliver VSV in preclinical models of NSCLC, in which BOECs were acquired from either C57/Bl6 mice or human donors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7039683	SNP1 and SNP2 700 bp elements, used in GFP and LacZ reporter constructs were (SNP1) chr12:53,340,250–53,340,950 and (SNP2) chr12:53,343,968–53,344,668 (hg19).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	All pts will be followed for relapse, EFS and OS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "pts", "will", "be", "followed", "for", "relapse", ",", "EFS", "and", "OS...
PMC9429973	The percent of patients achieving OPR at each time point by regimen are: 68% vs. 41% (p=0.002) after C1, 75% vs. 39% (P< 0.0001) after C3 and 92% vs. 55% (p<0.0001) at EOT for FLAG-GO and FLAG-IDA respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11321678	Dysfunction of NTRs has been linked to neuronal system diseases due to their crucial role in neuron communication.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Dysfunction", "of", "NTRs", "has", "be...
PMC7334607	For example, the evolution of collateral resistance to dactinomycin in all four A673 experimental replicates is consistently stable in the data presented here.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC5673955	For all studies, RrA E149R, V150P, F151T mutant was used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "all", "studies", ",", "RrA", "E149R", ",", "V150P", ...
PMC11754094	Streptococcus pyogenes Cas9 (SpCas9) was ordered from Enzynomics.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Streptococcus", "pyogenes", "Cas9", "(", "SpCas9", ")", "was", "ordered", "from", "Enzynomics", ...
PMC11128598	These values were calculated using Compusyn Software.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "values", "were", "calculated", "using", "Compusyn", "Software", "." ] } ]
PMC6222726	Guayadequiol (6) was isolated for the first time from Bupleurum salicifolium .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Guayadequiol", "(", "6", ")", "was", "isolated", "for", "the", "first...
PMC5330095	Authors Henry Lowe and Ngeh Toyang are on the management of Medicanja Jamaica Ltd., and Flavocure Biotech LLC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Authors", "Henry", "Lowe", "and",...
PMC10932641	Among the various types of RNA, long noncoding RNA (lncRNA) is a transcription product of more than 200 nucleotides but has no obvious protein-coding potential (5,6).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5854676	Schematic illustration of MgO based PDT by manifold techniques.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Schematic", "illustration", "of", "MgO", "based", "PDT", "by", "manifold", "techniques", "." ] } ]
PMC5673060	Cells (2000/well) were seeded in a 96-well plate and treated with inhibitors at the indicated doses for 72 h prior to assessment of cell viability using Cell Titre Glo (Promega), following the manufacturer's recommendations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Primary endpoint was overall response rate (ORR) by independent central review.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Primary", "endpoint", "was", "overall", "response", "rate", "(", "ORR", ...
PMC11629461	These data suggest that UVA irradiation activated NOX5, possibly by O2 generated in a UVA‐driven type II photodynamic action.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "data", "suggest", ...
PMC9844987	For prQTL detection, all 29,001 promoters were tested using TPM-normalized expression values.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "prQTL", "detection", ",", "all", "29,001", "promoters", "were", ...
PMC11347429	Overview supplementary material at online repositories.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overview", "supplementary", "material", "at", "online", "repositories", "." ] } ]
PMC11222184	While XL-888 led to a decrease in the expression of FGF2, SERPINF1 and VEGFC genes, Debio0932 triggered a reduction in the expression of ANGPT1, ANGPT2, KDR, and TEK genes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10938336	This evaluation encompassed key molecular properties, including molecular weight (MolWt), oral bioavailability (OB), the number of hydrogen bond acceptors (Num.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11534377	10 minutes at 25°C, followed by 2h of incubation at 37°C, then 5 minutes at 85°C and then the samples were kept on ice or stored at −20°C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10957991	This was evident in both TRPV4 siRNA and TRPV4 CRISPR cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "was", "evident", "in", "both", "TRPV4", "siRNA", "and", "TRPV4", "...
PMC9429973	A. Kittai, Y. Huang, J. Fisher, S. Bhat, M. Grever, E. Paskett, K. Rogers, J. Woyach The Ohio State University, Columbus, United States of America Background: Therapy for chronic lymphocytic leukemia (CLL) has changed dramatically over the past 20 years.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11441402	These methods were assessed based on their effectiveness in detecting the cell numbers of two adherent cell lines and one suspension cell line.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These",...
PMC11482552	All these factors can impact the quality assurance of molecular HPV testing of clinical samples .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "these", "factors", "can", "impact", "the", "quality"...
PMC11539788	P-R) Protein levels of AKT, p-AKT T473, mTOR, p-mTOR S2448, S6K1, and p-S6K1 T389 in T24 and 5637 cells after RNF19A was knocked down. *	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "...
PMC7823217	Based on histological classification, there are two main types of lung cancers- I) small cell lung cancer and II) Non-small cell lung cancer .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11476666	However, in the present study, no significant induction of apoptosis was observed for either DHS or RSV up to 30 μM, as confirmed by the lack of the sub-G1 peak and the absence of morphological apoptotic features.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11476004	Genome instability is a characteristic trait of tumours and includes changes in DNA and in chromosomes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Genome", "instability", "is", "a", "characteristic", "...
PMC11380454	In the present study, we chose to investigate a variety of malignant cell types to determine if the effects of both tellurium compounds presented here were specific to a certain cell type.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10502403	NOD/Shi-scid/IL-2Rγ (NOG) female mice were purchased from the Central Institute for Experimental Animals (Kawasaki, Japan).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "NOD/Shi-scid/IL-2Rγ", "(", "...
PMC11583010	ETx-22 antitumor effect was further evaluated and found effective in ovarian PDX models PDX OV2018 and PDX OV2423 (H-score = 202 and 144, respectively; Fig. 6G and H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11770199	In brief, 1.5 × 10 cells were seeded in 12-well plates and cultured overnight.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "brief", ",", "1.5", "×", "10", "cells", "were",...
PMC9429973	Mean neutrophil counts initially declined with placebo+AZA before slowly recovering to near-normal levels after 36-40 weeks.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mean", "neutrophil", "counts", "initially", ...
PMC11739504	However, the role of acetylation in primary cilia regulation remains unclear.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "role", "of", "acetylation", "in", "primary", "cilia", ...
PMC11612794	We introduced a construct containing either GFP-Dsn1 or GFP-Dsn1 into the endogenous Dsn1 locus of CENP-C/CENP-T cells (Figures S2G and S7A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11698348	Cells were then stained with secondary antibody APC-streptavidin (Biolegend, USA) for 1 hour at 4°C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "then", ...
PMC11591038	Additionally, the effect of the HIF signaling greatly depends on the extent of hypoxic magnitude, severity of the stress, and the cell types that express HIF-1α.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11532793	The set of novel isoform-switching genes included the proto-oncogene BRAF (BRAF-204, −0.88 log fold-change, adjusted P-value 1.183 × 10; BRAF-206, 1.13 log fold-change, adjusted P-value 1.085 × 10) for which cancer-causing mutations in lung adenocarcinoma have been previously identified (26).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7090062	P < 0.01 vs. non-specific control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", "<", "0.01", "vs.", "non-specific", "control", "." ] } ]
PMC5925824	To evaluate the ability of LY3300054 to bind to PD-L1 physiologically expressed on the surface of cells we performed flow cytometry analyses on the tumor cell lines with known surface PD-L1status.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11704135	Subsequent sulfoxidation of these derivatives (2–5) using hydrogen peroxide and glacial acetic acid yielded a diverse array of pyrimidine sulfonyl methanone derivatives (6–9).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10993311	Transcription regulatory region DNA binding, like the peroxisome proliferator (PPAR)γ, a transcription factor described in obesity, is involved in adipose tissue differentiation, lipogenesis, and lipid metabolism (Huang et al., 2018).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11224206	The information has not been given in precise quantitative terms because such data do not exist; rather, this review of the literature has revealed an extensive research agenda which needs to be addressed with urgency, especially as the global ambient temperature will continue to increase for the foreseeable future.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11216402	We compared the expression of GC cell lines to these single-cell clusters and found high similarity between stomach clusters 2 and 5 with Epi-like GC cell lines (Fig. 5B) and high similarity between Mes-like GC cell lines and fibroblast cluster 6 (Fig. 5C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4355729	With the downregulation of PIK3R1 in 786 and A-704 mutated cells, the mRNA expression of CTNNB1 was higher than that in 786-O and A-704 WT cells (Fig. 5a).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-...
PMC10957991	Also, total amount and levels of p63 positive nuclei were decreased upon deprivation of TRPV4 (Fig. 2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Also", ",", "total", "...
PMC11638255	We demonstrate that copper chelation favorably alters the infiltration and antitumor activity of both lymphoid and myeloid compartments, specifically neutrophils.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "demonstrate", ...
PMC11257203	These results support the idea that one of the possible mechanisms of curcumin for protection against indomethacin-induced genotoxicity might be through reducing the level of oxidative stress.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11704135	7FT-IR spectra of sulfonyl sulfonyl pyrimidine derivatives (13–15).Fig.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "7FT-IR", "spectra", "of", "sulfonyl", "sulfonyl", "pyrimidine", "derivatives", "(13–15).Fig", "." ] } ]

PMC11087766

Infections were incubated rotating at 30 °C and then inoculated on 1% agarose pads containing 25% LB and 1 µg/mL DAPI and dried for 5 min at room temperature before a coverslip was applied.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7348793

Shorter NUMTs can not be amplified with our long-range primers), (b) our primers should have sufficient homology to NUMTs, and (c) the breaking point for NUMT insertion should have occurred within the short 777 bp region between our primers for long-range amplification, which is unlikely.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11345828

The combined organic layers were washed with sat.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "combined", "organic", "layers", "were", "washed", "with", "sat", "." ] } ]

PMC9429973

Comparatively, OS was longer with RUX vs PBO/BAT regardless of disease duration.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Comparatively", ",", "OS", "was", "longer", "with", "RUX", "vs", "PBO...

PMC10587429

Return the mice to their microisolator cages, provide proper food and water and wait for 24 hours before injecting the CD34 HSCs.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Return"...

PMC10454535

One-way analysis of variance and Dunnett’s multiple comparisons tests were run using GraphPad Prism 9.3.1 software (GraphPad Software, Inc., San Diego, CA, USA) to determine statistical significance.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10698968

Erythrosine B stain was used to discriminate and count viable cells through Countess™ II FL Cell Counter (Life Technologies).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Erythrosine", ...

PMC9429973

Median age at ponatinib start was 61 years for CML and 56 years for Ph+ALL patients.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Median", "age", "at", "ponatinib", "start", "was", ...

PMC11300639

k 786-O and A498 cells were transfected with indicates plasmids for 48 h. Cells were harvested for CCK-8, transwell and tube formation assay.

[ { "tags": [ "B-CellLine", "I-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...

PMC11772585

K The protein levels of METTL1 and ATF4 in normal specimens (n = 7) and cSCC tumors (n = 36) with different tumor grade were detected by IHC on continuous sections.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC4005030

Also this is a folk remedy for abscesses, bilious conditions, cancer, cough, debility, dyspepsia, dysuria, fever, hangover, heart ailments, hypertension , neurosis, scurvy, and strangury.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11543885

For western blot analysis, use 12 μL of the whole cell lysate and 15 μL of the eluted biotinylated proteins.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "western", ...

PMC9429973

All calculations were made in SPSS program version 26.0.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "calculations", "were", "made", "in", "SPSS", "program", "version", "26.0", "." ] } ]

PMC11607321

This reduces the number of trainable parameters by 39.2% while maintaining low reconstruction error.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "reduces", "the", "number", "of", "trainable", "para...

PMC7602170

Until recently, KIT (CD117), a tyrosine kinase receptor, has been the main tool for the validation of GISTs with a positivity rate in immunohistochemistry of more than 90% (Table 1) .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11657695

D Gene expression (Log2 normalized expression) of KCNA2 in Mesenchymal Stem Cells (MSCs) coming from thirty healthy donors (30 donors) and in Ewing sarcoma patients (117 patients) (Mann–Whitney test).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Josip Benčević, Slavonski Brod; School of Medicine, University of Osijek Josip Juraj Strossmayer, Osijek; Internal medicine department, General Hospital dr.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC11755519

What brings more attention and potential implications is the fact that cancer cells secrete more EVs than non-malignant cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "What", "brings", "more", "attenti...

PMC11802855

A The optimal cut-off value of the relative expression level of CXCL7.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "The", "optimal", "cut-off", "value", "of", "the", "relative", "expression",...

PMC6133382

Serial dilutions of monoclonal antibodies were added in a range from 10 μg/mL to 0.0001 μg/mL and then incubated at 25 °C for 90 minutes with shaking.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11401358

However, it is difficult to test the antioxidant mechanism with intact SF because SF has a large molecular weight of over 5000 amino acids.

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PMC11400680

Based on the comparative results, he proved that U-Net+ consumes a fewer number of weights, and shorter inference time while providing more accurate segmentations.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC11592837

Contrarily, analyzing the same time series in all samples, the Alu index tended to increase moderately until 4 h, with control cells starting at 0.72 and reaching a maximum of 1.1, but then tailing off to 0.73 (Figure 7D).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11377827

Each dot represents the mean fluorescence intensity (AU at 488 nm) of a biological replicate.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "dot", "represents", "the", "mean", ...

PMC5810978

A single genotype, genogroup I and genotype 2 (GI.2), was predominantly detected from acute non-bacterial gastroenteritis outbreaks throughout Japan in 2012 and 2013 .

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PMC10094992

Statistical evaluation of the differential analyses was performed by one-way ANOVA and Student’s t-test.

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PMC9429973

Thrombomodulin, among other factors, plays a key role as an anticoagulant factor through activation of protein C and subsequent limitation of thrombin generation.

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PMC11420784

n = 3 slides.

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PMC11680049

Previously, when studying the localization of polyphenols in plant tissues, researchers in many cases noted the accumulation of flavonoids mainly in the epidermal layers of leaves .

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PMC11740399

The mice were intraperitoneally injected with 50 mg/kg 3025@ML every day and 10 mg/kg OXA once a week.

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PMC7762347

Nevertheless, additional studies are needed to completely understand its genotoxic properties.

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PMC11095939

Because of the limited number of cKO animals, we could only assess the effects at 6 hr post-PHx.

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PMC11788920

Schematic of the DNA construct and CRISPR–dCas9 target sites 1–4 on the template and NTSs.

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PMC9985266

Pathological phenomena were observed, such as a thickened alveolar septum, infiltrating inflammatory cells, and a large number of collapsed alveoli, and the degree of PF became more severe with increasing induction time (Additional file 1: Fig. S1A).

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PMC11697703

MAPK8 is required for netrin-1 signaling through DCC (DCC Netrin 1 receptor), which is required during callosal projection guidance.

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PMC11489275

The lowest tertile of lymphocytes group as reference, the risk of death within 1 month in the middle and the highest tertile group was 0.745 times (95% CI 0.416–1.336) and 0.497 times (95% CI 0.260–0.949), respectively (Fig. 1C, D).

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PMC6617630

In summary, we identified an in vitro model for DHL/THL DLBCLs and provide evidence for the therapeutic potential of BET inhibitor alone or in combination with BCL2 inhibitor.

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PMC9429973

We previously demonstrated that leukemia-derived sEV are involved in the re-education of surrounding cells and increased immune escape.

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PMC11209164

The spread of the virus was also evaluated using a plaque assay designed to measure plaque size, revealing that TPF significantly increased the area of viral plaques within a monolayer of the 786-0 cells, as determined by Coomassie blue staining as shown in (Figure 1G).

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PMC11106977

Osteoblasts, which are bone-forming cells, play a crucial role in the modeling and remodeling of bones.

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PMC11672881

The integration of DEGs with the heatmap and GO analyses provides a comprehensive view of how TQ, CU, and their combination impact A375 cell lines.

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PMC9429973

Patients were randomized 1:1 to either Sequence A: DEC-C (35 mg DEC/100 mg cedazuridine) in Cycle 1 followed by IV-DEC at 20 mg/m in Cycle 2, or Sequence B: receiving IV-DEC in Cycle 1 followed by DEC-C on Cycle 2 to compare PK [primary endpoint Area Under the Curve (AUC) equivalence over 5 days of dosing].

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PMC7887261

Oncoarray case–control study (17,878 LCs vs. 13,425 controls; dbGaP phs001273): The OncoArray consortium is a network created to increase understanding of the genetic architecture of common cancers.

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PMC10898159

SH3BP2 promotes the expression of mutant KIT via up-regulation of the expression of microphthalmia-associated transcription factors (MITF) and ETV1.

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PMC10976516

Rincón et al. used the syngeneic murine CMT64 lung cancer cell line to produce a human adenovirus semi-permissive tumor model.

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PMC10813895

Although loss of fidelity with age is observed in both lineages, it is most pronounced in luminal epithelial cells.

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PMC11033180

Moreover, the reduced level of synapsin 1 phosphorylation at Ser603 was not observed in neurons cocultured with COS cells expressing Sema5A-Fc-S956G (Figure 7D).

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PMC8658661

However, even after the publication of such articles, researchers continue to call the genesis of the cell line differently.

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PMC4695073

IC50 values of cisplatin were measured by MTT assay after knocking down XPA expression in NPC cell line HONE1 and CNE1 cells by transient transfection of siRNAs (NC-si as negative control) for 24 h. A., B. Representative dose-dependent cell viability curves in HONE1 and CNE1 cells (inner, Western blotting for XPA expression).

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PMC10728200

Furthermore, STUB1 overexpression significantly increased GPX4 ubiquitination (Fig. 4E).

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PMC10976516

Patel et al. (Table 2) used ex-vivo-infected BOECs to deliver VSV in preclinical models of NSCLC, in which BOECs were acquired from either C57/Bl6 mice or human donors.

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PMC7039683

SNP1 and SNP2 700 bp elements, used in GFP and LacZ reporter constructs were (SNP1) chr12:53,340,250–53,340,950 and (SNP2) chr12:53,343,968–53,344,668 (hg19).

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PMC9429973

All pts will be followed for relapse, EFS and OS.

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PMC9429973

The percent of patients achieving OPR at each time point by regimen are: 68% vs. 41% (p=0.002) after C1, 75% vs. 39% (P< 0.0001) after C3 and 92% vs. 55% (p<0.0001) at EOT for FLAG-GO and FLAG-IDA respectively.

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PMC11321678

Dysfunction of NTRs has been linked to neuronal system diseases due to their crucial role in neuron communication.

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PMC7334607

For example, the evolution of collateral resistance to dactinomycin in all four A673 experimental replicates is consistently stable in the data presented here.

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PMC5673955

For all studies, RrA E149R, V150P, F151T mutant was used.

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PMC11754094

Streptococcus pyogenes Cas9 (SpCas9) was ordered from Enzynomics.

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PMC11128598

These values were calculated using Compusyn Software.

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PMC6222726

Guayadequiol (6) was isolated for the first time from Bupleurum salicifolium .

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PMC5330095

Authors Henry Lowe and Ngeh Toyang are on the management of Medicanja Jamaica Ltd., and Flavocure Biotech LLC.

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PMC10932641

Among the various types of RNA, long noncoding RNA (lncRNA) is a transcription product of more than 200 nucleotides but has no obvious protein-coding potential (5,6).

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PMC5854676

Schematic illustration of MgO based PDT by manifold techniques.

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PMC5673060

Cells (2000/well) were seeded in a 96-well plate and treated with inhibitors at the indicated doses for 72 h prior to assessment of cell viability using Cell Titre Glo (Promega), following the manufacturer's recommendations.

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PMC9429973

Primary endpoint was overall response rate (ORR) by independent central review.

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PMC11629461

These data suggest that UVA irradiation activated NOX5, possibly by O2 generated in a UVA‐driven type II photodynamic action.

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PMC9844987

For prQTL detection, all 29,001 promoters were tested using TPM-normalized expression values.

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PMC11347429

Overview supplementary material at online repositories.

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PMC11222184

While XL-888 led to a decrease in the expression of FGF2, SERPINF1 and VEGFC genes, Debio0932 triggered a reduction in the expression of ANGPT1, ANGPT2, KDR, and TEK genes.

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PMC10938336

This evaluation encompassed key molecular properties, including molecular weight (MolWt), oral bioavailability (OB), the number of hydrogen bond acceptors (Num.

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PMC11534377

10 minutes at 25°C, followed by 2h of incubation at 37°C, then 5 minutes at 85°C and then the samples were kept on ice or stored at −20°C.

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PMC10957991

This was evident in both TRPV4 siRNA and TRPV4 CRISPR cell lines.

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PMC9429973

A. Kittai, Y. Huang, J. Fisher, S. Bhat, M. Grever, E. Paskett, K. Rogers, J. Woyach The Ohio State University, Columbus, United States of America Background: Therapy for chronic lymphocytic leukemia (CLL) has changed dramatically over the past 20 years.

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PMC11441402

These methods were assessed based on their effectiveness in detecting the cell numbers of two adherent cell lines and one suspension cell line.

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PMC11482552

All these factors can impact the quality assurance of molecular HPV testing of clinical samples .

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PMC11539788

P-R) Protein levels of AKT, p-AKT T473, mTOR, p-mTOR S2448, S6K1, and p-S6K1 T389 in T24 and 5637 cells after RNF19A was knocked down. *

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PMC7823217

Based on histological classification, there are two main types of lung cancers- I) small cell lung cancer and II) Non-small cell lung cancer .

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PMC11476666

However, in the present study, no significant induction of apoptosis was observed for either DHS or RSV up to 30 μM, as confirmed by the lack of the sub-G1 peak and the absence of morphological apoptotic features.

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PMC11476004

Genome instability is a characteristic trait of tumours and includes changes in DNA and in chromosomes.

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PMC11380454

In the present study, we chose to investigate a variety of malignant cell types to determine if the effects of both tellurium compounds presented here were specific to a certain cell type.

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PMC10502403

NOD/Shi-scid/IL-2Rγ (NOG) female mice were purchased from the Central Institute for Experimental Animals (Kawasaki, Japan).

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PMC11583010

ETx-22 antitumor effect was further evaluated and found effective in ovarian PDX models PDX OV2018 and PDX OV2423 (H-score = 202 and 144, respectively; Fig. 6G and H).

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PMC11770199

In brief, 1.5 × 10 cells were seeded in 12-well plates and cultured overnight.

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PMC9429973

Mean neutrophil counts initially declined with placebo+AZA before slowly recovering to near-normal levels after 36-40 weeks.

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PMC11739504

However, the role of acetylation in primary cilia regulation remains unclear.

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PMC11612794

We introduced a construct containing either GFP-Dsn1 or GFP-Dsn1 into the endogenous Dsn1 locus of CENP-C/CENP-T cells (Figures S2G and S7A).

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PMC11698348

Cells were then stained with secondary antibody APC-streptavidin (Biolegend, USA) for 1 hour at 4°C.

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PMC11591038

Additionally, the effect of the HIF signaling greatly depends on the extent of hypoxic magnitude, severity of the stress, and the cell types that express HIF-1α.

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PMC11532793

The set of novel isoform-switching genes included the proto-oncogene BRAF (BRAF-204, −0.88 log fold-change, adjusted P-value 1.183 × 10; BRAF-206, 1.13 log fold-change, adjusted P-value 1.085 × 10) for which cancer-causing mutations in lung adenocarcinoma have been previously identified (26).

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PMC7090062

P < 0.01 vs. non-specific control.

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PMC5925824

To evaluate the ability of LY3300054 to bind to PD-L1 physiologically expressed on the surface of cells we performed flow cytometry analyses on the tumor cell lines with known surface PD-L1status.

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PMC11704135

Subsequent sulfoxidation of these derivatives (2–5) using hydrogen peroxide and glacial acetic acid yielded a diverse array of pyrimidine sulfonyl methanone derivatives (6–9).

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PMC10993311

Transcription regulatory region DNA binding, like the peroxisome proliferator (PPAR)γ, a transcription factor described in obesity, is involved in adipose tissue differentiation, lipogenesis, and lipid metabolism (Huang et al., 2018).

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PMC11224206

The information has not been given in precise quantitative terms because such data do not exist; rather, this review of the literature has revealed an extensive research agenda which needs to be addressed with urgency, especially as the global ambient temperature will continue to increase for the foreseeable future.

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PMC11216402

We compared the expression of GC cell lines to these single-cell clusters and found high similarity between stomach clusters 2 and 5 with Epi-like GC cell lines (Fig. 5B) and high similarity between Mes-like GC cell lines and fibroblast cluster 6 (Fig. 5C).

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PMC4355729

With the downregulation of PIK3R1 in 786 and A-704 mutated cells, the mRNA expression of CTNNB1 was higher than that in 786-O and A-704 WT cells (Fig. 5a).

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PMC10957991

Also, total amount and levels of p63 positive nuclei were decreased upon deprivation of TRPV4 (Fig. 2).

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PMC11638255

We demonstrate that copper chelation favorably alters the infiltration and antitumor activity of both lymphoid and myeloid compartments, specifically neutrophils.

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PMC11257203

These results support the idea that one of the possible mechanisms of curcumin for protection against indomethacin-induced genotoxicity might be through reducing the level of oxidative stress.

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PMC11704135

7FT-IR spectra of sulfonyl sulfonyl pyrimidine derivatives (13–15).Fig.

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