OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC10818573	The PCR reaction conditions included an initial denaturation temperature of 95 °C for 3 min; 35 cycles of denaturation at 95 °C for 15 s, annealing at 56 °C for 15 s, and extension at 72 °C for 60 s; and a final extension at 72 °C for 5 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Diversity index at day 0 of HCT was not different between patients who experienced fever and/or aGVHD and patients who did not.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Diversity", ...
PMC11298021	To investigate the expression of miRNAs and target genes, TRIzol reagent (Invitrogen; Thermo Fisher Scientific, Inc., USA) was used to extract total RNA in accordance with the manufacturer's instructions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11678368	Such a good agreement between experimental and theoretical spectra indicates that the suggested structures of the complexes are correct.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Such", "a", "good", "agreement", ...
PMC11607764	Therefore, we need to carry out more experimental studies to verify and improve the existing findings.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "we", "need", "to", "carry...
PMC11592837	To the authors’ knowledge, a difference in the timing of cellular response between both topoisomerase II inhibitors has not been reported previously.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC6222726	Once dried, the resin obtained by Bursera spp.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Once", "dried", ",", "the", "resin", "obtained", "by", "Bursera", "spp", "." ] } ]
PMC9429973	Among those who achieved CR after Hyper-CVAD induction, 25 (52%) received Hyper-CVAD consolidation chemotherapy ± TKI while 24 (50%) proceeded to alloSCT in first CR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11200978	Briefly, culture media and lifted cells were removed from sample wells and collected in individual 15 mL centrifuge tubes for each condition.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Briefly...
PMC9780037	Elements were not drawn to scale.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Elements", "were", "not", "drawn", "to", "scale", "." ] } ]
PMC11412721	Raji Burkitt lymphoma cells were transfected with a PX459 vector expressing gRNA #4 or #5 (or no gRNA for control) using Nucleofector Amaxa kit V (Lonza), and selection was carried out with 1 μg/ml puromycin for 3 weeks to obtain stably transfected cells.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11628309	Ninety percent of these cases are attributed to just ten of the most common neurological disorders, including Parkinson’s disease (PD), whose incidence is expected to increase by a factor of 1.6 between 2010 and 2030.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11757230	Black arrows indicate necrotic nests in the inner layer of the tumor mass.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Black", "arrows", "indicate", "necrotic", "nests", "in", "the", "inner", ...
PMC11782780	The membrane was sealed with 5% skim milk for 1 ‍h and then incubated at 4°C overnight with primary antibodies: rabbit anti-human CD133, CD44, Oct-4, HK2, PFKP, PKM2, and GAPDH antibodies (Abcam, Cambridge, UK).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6181431	However, in another sample (MT_006), an inactivating TSC1 mutation went from zero cancer cell fraction in the pre-treatment sample to clonal in the post-treatment sample, in direct contrast to this model.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9436459	bombycis16Type A, 5 (5, 6, 28, 31, and 40);Type B, 2 (64 and 72);Type C, 4 (81, 83, 86, and 87);Type D, 2 (92 and 93);Type F, 2 (130 and 131);Type I, 1 (162)10M.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11467964	At present, many studies reported that BM participated in many signs of progression, such as diabetes, hypertension, and cancer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", ...
PMC11721277	The structure of chlorin p6 trimethyl ester allows for chemical modifications of the pyrrole A of the chlorin macrocycle, as well as the aliphatic ester group at position 17.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11774747	Created with BioRender.com.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "Created", "with", "BioRender.com", "." ] } ]
PMC10135767	Kindlin-3, a member of the Kindlin family specifically expressed in leukocytes, contributes to inside-out and outside-in signaling .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Kindlin-3", ",", "a", "member", ...
PMC8864075	Some herbals and their extracts have been reported to have therapeutic effects on cancer, including Scutellaria baicalensis (Sato et al., 2013; Bie et al., 2017; Zhang et al., 2018; Hsiao et al., 2019), whose main components are flavonoids.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9111184	After being in contact with cells for 24 h, The percentage of toxicity for a concentration of 1 mg/mL of hydroxycinnamic acid derivatives was lower than 50% whereas EZ had an IC50 of 228.42 ± 29.5 μM (Table 1).Table 1Cytotoxicity towards Caco-2 cell line of 1 mg/mL of hydroxycinnamic acid derivatives (%) and IC50 (μM) for EzetemibeTable 1m-CAChARAEZCaco-2 cell line45.20 ± 1.44%34.28 ± 0.8%42.34 ± 3.54%228.42 ± 329.5aaIC50 (μM).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9895440	Confirmation of malignancy was obtained from a board-certified pathologist.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Confirmation", "of", "malignancy", "was", "obtained", "from", "a", "board-certified", "pathologist", "." ...
PMC5963610	The only report in the literature, which uses the NGcGM3, showed a lower inhibition of the EGFR phosphorylation by this ganglioside variant .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11271800	SPARCL1 is closely associated with neovascularization in GIST and involved in GIST cell progression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SPARCL1", "is", "closely", "associated", "with", "neovascularization", ...
PMC11588085	The mesenchymal-to-epithelial transition (MET) occurs once the cells invade other organs and transition back to an epithelial state, which allows them to establish new tumor niches and proliferate (65).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11585254	There was a concentration-dependent increase in the BRET response, consistent with β-arrestin1 or β-arrestin2 recruitment to ligand-activated CXCR5 (Fig. 1B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There",...
PMC11782508	The concentration and purity of the isolated DNA were assessed using a NanoDrop ND-2000 spectrophotometer (Thermo Fisher Scientific, USA) and 1% (w/v) agarose gel electrophoresis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11471157	Arrows indicate small spheroids.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Arrows", "indicate", "small", "spheroids", "." ] } ]
PMC11026382	All sublibraries were inoculated, grown, and sampled in triplicate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "sublibraries", "were", "inoculated", ",", "grown", ",", "and", "sampled", "in"...
PMC10452486	Table 3, Table 4 and Table 5 document the presence of tyrosyl residues in α1 > α2 > α3 domains of HCs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Table",...
PMC9429973	No differences were found between ChAdOx1-S and mRNA vaccines, and no increase in thrombin generation or D-dimer was found after mRNA vaccines compared with baseline levels.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10024132	To overcome this issue, adoptive transfer of blinatumomab-secreting γ9δ2 T cells may be able to provide healthy and functional T cells that potentially compensate for the lack of CD3 T cells needed for optimal blinatumomab activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8009078	The Glide score of two control molecules, Camostat and Ambroxol was found to be − 7.21 and − 6.23 kcal/mol, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC9429973	Targeted and untargeted metabolomic profiling through metabolomic analysis was performed to explore the relationship between the metabolome and ITP.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Targeted", "and", "untargeted", "...
PMC11525028	B and C) Cell viability (B) and Bliss score (C) for paliperidone and AG-401 combined treatment. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "B", "and", ...
PMC10196713	These results indicated that cisplatin could promote ferroptosis by enhancing the mitochondrial membrane potential.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "results", "indicated", "that", "cisplatin", "could", "promote...
PMC11583010	As EV has demonstrated objective responses in locally advanced or metastatic urothelial carcinoma, we compared the antitumor activity of ETx-22 to EV in bladder-derived PDXs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11766309	We observed that YKT6 was a substantial risk factor for breast invasive carcinoma (BRCA), GBM, and KIRC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "observed", ...
PMC11622247	This synthesis protocol proved robust and provided rapid access to multi-labelled oligonucleotides.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "synthesis", "protocol", "proved", "robust", "and", "provided", "rapid", ...
PMC10907726	For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC4685411	Introducing limits for these parameters prevents questionable solutions of the algorithm and allows user specifications regarding product quality or cell proliferation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Introducing", "limits",...
PMC11478724	indicates Significance at the P < 0.0001 level) According to the results, PMX-treated cells produced significantly more ROS than the control cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11680562	Fig. 10The Zone of inhibition assay on E. coli presented in the agar-wall diffusion plate (a) and the bar diagram represent the inhibition of the Zone of E. coli plate (b) [Data represent as mean ± SD (n = 3)] The Zone of inhibition assay on E. coli presented in the agar-wall diffusion plate (a) and the bar diagram represent the inhibition of the Zone of E. coli plate (b) [Data represent as mean ± SD (n = 3)] In the context of cervical cancer, which is often caused by severe HPV infection, the vaginal pH may frequently increase to levels above 4.5, making it less acidic .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	In our media FLT3 inhibitors are not approved as maintenance therapy after HSCT.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "our", "media", "FLT3", "inhibitors", "are", "not", "approved", ...
PMC11653533	Furthermore, extracts from F. deltoidea leaves demonstrated promising protective effects against photo-aging in UVB-irradiated skin cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "extracts", "from", "F.", ...
PMC9429973	PB biomarkers were evaluated by flow cytometry (n=87) and plasma cytokines by ELISA (n=70).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PB", "biomarkers", "were", "evaluated", ...
PMC6889484	C and D) Replication kinetics of recombinant subtype AE in parental (C) CEM and (D) PM1 cells, with no detectable virus up to 30 days post-infection in CEM/D128K and PM1/D128K cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "...
PMC11746942	E Immunofluorescence staining of S1PR3 (red) in patients before and after psoriasis treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "E", "Immunofluorescence", "staining", "of", "S1PR3", "(", "...
PMC11694066	Still, whether such effects are only observed in traditionally immunogenic diseases, such as NSCLC or melanoma, or also operate in DSRCT remains to be assessed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11732635	According to the clinical manifestations, elevated EBV DNA levels, and positive EBER status, the patient was diagnosed with CAEBV infection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Accordi...
PMC11766174	For the SIV-infected non-human primate model, PBMCs were isolated from rhesus macaques pre-infection (day −11), post infection (day 14) with SIVmac239m , and post-treatment (day 84; 28 days post-treatment initiation with daily subcutaneous 2.5 mg/kg dolutegravir, 40 mg/kg emtricitabine, 5.1 mg/kg tenofovir disoproxil fumarate) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9577200	The suspension (susp.)	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "suspension", "(", "susp", ".", ")" ] } ]
PMC8584666	GPI-80 is a member of the pantetheinase gene family that consists of pantetheinase/VNN1, which produces pantothenic acid (vitamin B5) and cysteamine from pantetheine .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9874064	Tumor growth inhibition curves of nude mice bearing PDX tumors treated with different drugs, ∗∗∗p < 0.001 (ordinary two-way ANOVA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11092382	and Taraxacum borealisinense Kitam. [	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "and", "Taraxacum", "borealisinense", "Kitam", ".", "[" ] } ]
PMC10589262	E Lysates from GIST and CC cells were deglycosylated using endoglycosidase H (Endo-H) or PNGase-F, and analyzed by western blotting.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "E", ...
PMC11350568	These characteristics render TfR1 an ideal component for constructing highly efficient TMPDS (Figure 1a,b).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "characteristics", "render", "TfR1",...
PMC11706297	Figures S1–S6).	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "Figures", "S1–S6", ")", "." ] } ]
PMC9429973	Results: As of this interim analysis (data cut: July 23, 2021), 45 patients received ≥1 dose (12 at 1.9 mg/kg Q8W; 4 at 1.9 mg/kg Q4W; 16 at 2.5 mg/kg Q4W; 13 at 2.5 mg/kg Q4W SPLIT).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11721295	For percentage positive cells – Ki67/ECAD, p-ERK/ECAD, CC3/ECAD, p-STAT3/PDGFR – we counted total nuclei and classified those that were positive for each individual stain as positive; all others were filtered out.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11618052	0.58 (hexane : ethyl acetate, 1 : 2, v/v).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "0.58", "(", "hexane", ":", "ethyl", "acetate", ",", "1", ":", "...
PMC9429973	The top procedure codes were for blood transfusion and Infusion Device into Superior Vena Cava.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "top", "procedure", "codes", "were", "for", "blood", ...
PMC5916734	The reduced dihydroquinone form of vitamin K (KH2 ) is converted to quinone 2,3-epoxide (K > O).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "reduced", "dihydroqui...
PMC5025404	Currently, a large number of drugs based on these antibodies are available.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Currently", ",", "a", "large", "number", "of", "drugs", "based", "on"...
PMC11307990	These DNA nanotapes show several advantages as a drug delivery system: (1) DNA nanotapes are well-defined nanostructures. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "DNA", "n...
PMC11429241	TPP provides us with a unique opportunity in terms of bringing standardization to 3D cell culture generation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TPP", "provides", "us", "with", "a", "uniqu...
PMC11727000	A similar result was also observed in two independent neuroblastoma datasets (Primary NRC n = 283, TARGET n = 249; Figure S2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11697189	The R package of RCircos was used to plot the copy number variation landscape of HSP genes in 23 pairs of chromosomes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "R", ...
PMC11055510	Subsequently, we found that in both SKOV3 and A2780 cells, RNase R treatment degraded the linear positive control (GAPDH) and MAN1A2, while circMAN1A2 was significantly resistant to the effects of RNase R (Figs. 1C and 1D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC9065483	according to the manufacturer’s protocol and quantified using a Nanodrop ND-1000 spectrophotometer (Thermo Fisher Scientific, Rockford, IL).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "according", ...
PMC9532503	For example, even though rituximab therapy is considered as remarkable treatment option for non-Hodgkin’s lymphoma, 30–50% of patients still do not respond clinically or display resistance to re-treatment .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Of them, 19 patients were excluded (primary CNS lymphoma: n=5, no rituximab: n=3, only palliative therapy: n=5, bendamustin: n=1, RCHOP-21: n=2, death during prephase treatment: n=2, missing documentation: n=1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7840816	Cell apoptosis was carried out using the Nucleosome ELISA kit.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "apoptosis", "was", "carried", "out", "using", "the", "Nucleosome", "ELISA", "kit", ...
PMC9014716	Approximately 24 hours later, the cells were treated with prepared drugs for 48 hours.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Approximately", "24", "hours", "later", ",", "the", "cells"...
PMC11323699	CD47 expression was scored by H-score using QuPath software: staining intensity (0, + 1, + 2, + 3) × % cells positive (0 to 100) = 0 to 300.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8164677	Tetrazolium salt is cleaved only by active mitochondria of living cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tetrazolium", "salt", "is", "cleaved", "only", "by", "active", "mitochondria", "of", ...
PMC11767725	The resultant hypoxic conditions activate hypoxia-inducible factor 1-alpha (HIF-1α) in keratinocytes and sebocytes, altering their metabolic activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "resultant", "hypoxic"...
PMC11082662	Elevated SMPDL3B contributes to the proliferation, migration, and invasion of ovarian carcinoma cells. •	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O" ], "tokens": [ "Elevated", "SMPDL3B", "contributes", "t...
PMC6034753	However, none of these proteins have demonstrated a conserved interaction motif, although the larger SH3 domain of Bcr-Abl1 and PI3-Kinase appear to be involved .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11001582	Following successful implantation, the cranial well was filled with warm sterile saline and the brain allowed to rest for at least 45 min before recordings.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11365983	Ethical approval was provided by the University of Alberta Health Research Ethics Board, with written informed consent received from all participants prior to their inclusion in the study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11700247	CART-19 cells were generated from CD45.1 congenic mice, and the CD45.1 marker was used to track the adoptively transferred CART-19 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CART-19", "c...
PMC8633974	mRNA loaded LNPs were formulated using non-turbulent microfluidic mixing using NanoAssmblr Ignite (Precision Nanosystem #NIN0001) using NxGen Cartridge (Precision Nanosystem #NIN0061) following manufacturer provided protocol.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11532793	Define the divided counts by .	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Define", "the", "divided", "counts", "by", "." ] } ]
PMC9964654	Micelles at the same concentrations used in the assay without inoculum were also tested, as negative controls.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Micelles", "at", "the", "same", "conce...
PMC11757230	We first investigated the effect of cADSCs on the proliferation of canine hematologic malignancy cells in vitro.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "first", "investigated", "the", "effect", ...
PMC9878562	Taken together, the data indicate that like in vitro lymphoma cells can also promote the migration of VAL-ko in vivo.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Taken", "together", ...
PMC11746948	Sample sizes: (c, g, h, j, l, m) n = 3 independent experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Sample", "sizes", ...
PMC11684821	Biological datasets are presented in the Supporting Data Values file.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Biological", "datasets", "are", "presented", "in", "the", "Supporting", "Data", "Values", "file"...
PMC11190238	The entire landscape is featured with ridges and valleys indicating the barriers between each lineage and state with different intermediates to feature a plasticity spectrum.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11681005	Transcription factor binding activity (z) and expression (Exp) of HES1, HES4, ASCL1, ASCL2, SMAD4 and FOXA1 in normal cells, luminal cancer cells, basal cancer cells, and TPCS from scATAC data. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10125312	To assess nanomaterial cytotoxicity, thiazolyl blue tetrazolium bromide (MTT) was used to determine the toxic potential of AuNR-PEG in cancerous and noncancerous cell lines of three different tissues.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Methods: The study included 80 DNA samples from AML patients admitted to the National Research Center for Hematology in 2019-2021 that were positive for NPM1 gene mutations detected by FA performed with the Nanophor-5 genetic analyzer (Synthol, Russia).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11683240	Subsequently, the experiment was performed as described in (B and C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Subsequently", ",", "the", "experiment", "was", "performed", "as", ...
PMC11656048	GPX4 oxidizes hydroperoxide and two molecules of reducing glutamate into lipid alcohols and oxidizing glutathione, acting as an antioxidant and free radical scavenger which can inhibit ferroptosis (Chen et al., 2022).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11525028	Data are presented as the mean ± SD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "presented", "as", "the", "mean", "±", "SD", "." ] } ]
PMC11706297	Thin layer chromatography (TLC) was performed using silica gel 60 F254 aluminum sheets (Merck, Darmstadt, Germany).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thin", "laye...
PMC11218145	Region of interest (ROI) was identified and quantified as total photon counts using Living Image software (PerkinElmer Inc, MA, USA) and expressed as photons/seconds/cm/sr.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11317131	Serine integrases catalyze the insertion of large DNA cargos at attachment (att) sites.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Serine", "integrases", "catalyze", "the", "insertion", "of", ...

PMC10818573

The PCR reaction conditions included an initial denaturation temperature of 95 °C for 3 min; 35 cycles of denaturation at 95 °C for 15 s, annealing at 56 °C for 15 s, and extension at 72 °C for 60 s; and a final extension at 72 °C for 5 min.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Diversity index at day 0 of HCT was not different between patients who experienced fever and/or aGVHD and patients who did not.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Diversity", ...

PMC11298021

To investigate the expression of miRNAs and target genes, TRIzol reagent (Invitrogen; Thermo Fisher Scientific, Inc., USA) was used to extract total RNA in accordance with the manufacturer's instructions.

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PMC11678368

Such a good agreement between experimental and theoretical spectra indicates that the suggested structures of the complexes are correct.

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PMC11607764

Therefore, we need to carry out more experimental studies to verify and improve the existing findings.

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PMC11592837

To the authors’ knowledge, a difference in the timing of cellular response between both topoisomerase II inhibitors has not been reported previously.

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PMC6222726

Once dried, the resin obtained by Bursera spp.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Once", "dried", ",", "the", "resin", "obtained", "by", "Bursera", "spp", "." ] } ]

PMC9429973

Among those who achieved CR after Hyper-CVAD induction, 25 (52%) received Hyper-CVAD consolidation chemotherapy ± TKI while 24 (50%) proceeded to alloSCT in first CR.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11200978

Briefly, culture media and lifted cells were removed from sample wells and collected in individual 15 mL centrifuge tubes for each condition.

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PMC9780037

Elements were not drawn to scale.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Elements", "were", "not", "drawn", "to", "scale", "." ] } ]

PMC11412721

Raji Burkitt lymphoma cells were transfected with a PX459 vector expressing gRNA #4 or #5 (or no gRNA for control) using Nucleofector Amaxa kit V (Lonza), and selection was carried out with 1 μg/ml puromycin for 3 weeks to obtain stably transfected cells.

[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11628309

Ninety percent of these cases are attributed to just ten of the most common neurological disorders, including Parkinson’s disease (PD), whose incidence is expected to increase by a factor of 1.6 between 2010 and 2030.

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PMC11757230

Black arrows indicate necrotic nests in the inner layer of the tumor mass.

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PMC11782780

The membrane was sealed with 5% skim milk for 1 ‍h and then incubated at 4°C overnight with primary antibodies: rabbit anti-human CD133, CD44, Oct-4, HK2, PFKP, PKM2, and GAPDH antibodies (Abcam, Cambridge, UK).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC6181431

However, in another sample (MT_006), an inactivating TSC1 mutation went from zero cancer cell fraction in the pre-treatment sample to clonal in the post-treatment sample, in direct contrast to this model.

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PMC9436459

bombycis16Type A, 5 (5, 6, 28, 31, and 40);Type B, 2 (64 and 72);Type C, 4 (81, 83, 86, and 87);Type D, 2 (92 and 93);Type F, 2 (130 and 131);Type I, 1 (162)10M.

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PMC11467964

At present, many studies reported that BM participated in many signs of progression, such as diabetes, hypertension, and cancer.

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PMC11721277

The structure of chlorin p6 trimethyl ester allows for chemical modifications of the pyrrole A of the chlorin macrocycle, as well as the aliphatic ester group at position 17.

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PMC11774747

Created with BioRender.com.

[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "Created", "with", "BioRender.com", "." ] } ]

PMC10135767

Kindlin-3, a member of the Kindlin family specifically expressed in leukocytes, contributes to inside-out and outside-in signaling .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Kindlin-3", ",", "a", "member", ...

PMC8864075

Some herbals and their extracts have been reported to have therapeutic effects on cancer, including Scutellaria baicalensis (Sato et al., 2013; Bie et al., 2017; Zhang et al., 2018; Hsiao et al., 2019), whose main components are flavonoids.

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PMC9111184

After being in contact with cells for 24 h, The percentage of toxicity for a concentration of 1 mg/mL of hydroxycinnamic acid derivatives was lower than 50% whereas EZ had an IC50 of 228.42 ± 29.5 μM (Table 1).Table 1Cytotoxicity towards Caco-2 cell line of 1 mg/mL of hydroxycinnamic acid derivatives (%) and IC50 (μM) for EzetemibeTable 1m-CAChARAEZCaco-2 cell line45.20 ± 1.44%34.28 ± 0.8%42.34 ± 3.54%228.42 ± 329.5aaIC50 (μM).

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PMC9895440

Confirmation of malignancy was obtained from a board-certified pathologist.

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PMC5963610

The only report in the literature, which uses the NGcGM3, showed a lower inhibition of the EGFR phosphorylation by this ganglioside variant .

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PMC11271800

SPARCL1 is closely associated with neovascularization in GIST and involved in GIST cell progression.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SPARCL1", "is", "closely", "associated", "with", "neovascularization", ...

PMC11588085

The mesenchymal-to-epithelial transition (MET) occurs once the cells invade other organs and transition back to an epithelial state, which allows them to establish new tumor niches and proliferate (65).

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PMC11585254

There was a concentration-dependent increase in the BRET response, consistent with β-arrestin1 or β-arrestin2 recruitment to ligand-activated CXCR5 (Fig. 1B).

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PMC11782508

The concentration and purity of the isolated DNA were assessed using a NanoDrop ND-2000 spectrophotometer (Thermo Fisher Scientific, USA) and 1% (w/v) agarose gel electrophoresis.

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PMC11471157

Arrows indicate small spheroids.

[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Arrows", "indicate", "small", "spheroids", "." ] } ]

PMC11026382

All sublibraries were inoculated, grown, and sampled in triplicate.

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PMC10452486

Table 3, Table 4 and Table 5 document the presence of tyrosyl residues in α1 > α2 > α3 domains of HCs.

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PMC9429973

No differences were found between ChAdOx1-S and mRNA vaccines, and no increase in thrombin generation or D-dimer was found after mRNA vaccines compared with baseline levels.

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PMC10024132

To overcome this issue, adoptive transfer of blinatumomab-secreting γ9δ2 T cells may be able to provide healthy and functional T cells that potentially compensate for the lack of CD3 T cells needed for optimal blinatumomab activity.

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PMC8009078

The Glide score of two control molecules, Camostat and Ambroxol was found to be − 7.21 and − 6.23 kcal/mol, respectively.

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PMC9429973

Targeted and untargeted metabolomic profiling through metabolomic analysis was performed to explore the relationship between the metabolome and ITP.

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PMC11525028

B and C) Cell viability (B) and Bliss score (C) for paliperidone and AG-401 combined treatment. (

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PMC10196713

These results indicated that cisplatin could promote ferroptosis by enhancing the mitochondrial membrane potential.

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PMC11583010

As EV has demonstrated objective responses in locally advanced or metastatic urothelial carcinoma, we compared the antitumor activity of ETx-22 to EV in bladder-derived PDXs.

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PMC11766309

We observed that YKT6 was a substantial risk factor for breast invasive carcinoma (BRCA), GBM, and KIRC.

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PMC11622247

This synthesis protocol proved robust and provided rapid access to multi-labelled oligonucleotides.

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PMC10907726

For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)

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PMC4685411

Introducing limits for these parameters prevents questionable solutions of the algorithm and allows user specifications regarding product quality or cell proliferation.

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PMC11478724

indicates Significance at the P < 0.0001 level) According to the results, PMX-treated cells produced significantly more ROS than the control cells.

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PMC11680562

Fig. 10The Zone of inhibition assay on E. coli presented in the agar-wall diffusion plate (a) and the bar diagram represent the inhibition of the Zone of E. coli plate (b) [Data represent as mean ± SD (n = 3)] The Zone of inhibition assay on E. coli presented in the agar-wall diffusion plate (a) and the bar diagram represent the inhibition of the Zone of E. coli plate (b) [Data represent as mean ± SD (n = 3)] In the context of cervical cancer, which is often caused by severe HPV infection, the vaginal pH may frequently increase to levels above 4.5, making it less acidic .

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PMC9429973

In our media FLT3 inhibitors are not approved as maintenance therapy after HSCT.

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PMC11653533

Furthermore, extracts from F. deltoidea leaves demonstrated promising protective effects against photo-aging in UVB-irradiated skin cells.

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PMC9429973

PB biomarkers were evaluated by flow cytometry (n=87) and plasma cytokines by ELISA (n=70).

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PMC6889484

C and D) Replication kinetics of recombinant subtype AE in parental (C) CEM and (D) PM1 cells, with no detectable virus up to 30 days post-infection in CEM/D128K and PM1/D128K cell lines.

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PMC11746942

E Immunofluorescence staining of S1PR3 (red) in patients before and after psoriasis treatment.

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PMC11694066

Still, whether such effects are only observed in traditionally immunogenic diseases, such as NSCLC or melanoma, or also operate in DSRCT remains to be assessed.

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PMC11732635

According to the clinical manifestations, elevated EBV DNA levels, and positive EBER status, the patient was diagnosed with CAEBV infection.

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PMC11766174

For the SIV-infected non-human primate model, PBMCs were isolated from rhesus macaques pre-infection (day −11), post infection (day 14) with SIVmac239m , and post-treatment (day 84; 28 days post-treatment initiation with daily subcutaneous 2.5 mg/kg dolutegravir, 40 mg/kg emtricitabine, 5.1 mg/kg tenofovir disoproxil fumarate) .

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PMC9577200

The suspension (susp.)

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PMC8584666

GPI-80 is a member of the pantetheinase gene family that consists of pantetheinase/VNN1, which produces pantothenic acid (vitamin B5) and cysteamine from pantetheine .

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PMC9874064

Tumor growth inhibition curves of nude mice bearing PDX tumors treated with different drugs, ∗∗∗p < 0.001 (ordinary two-way ANOVA).

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PMC11092382

and Taraxacum borealisinense Kitam. [

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PMC10589262

E Lysates from GIST and CC cells were deglycosylated using endoglycosidase H (Endo-H) or PNGase-F, and analyzed by western blotting.

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PMC11350568

These characteristics render TfR1 an ideal component for constructing highly efficient TMPDS (Figure 1a,b).

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PMC11706297

Figures S1–S6).

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PMC9429973

Results: As of this interim analysis (data cut: July 23, 2021), 45 patients received ≥1 dose (12 at 1.9 mg/kg Q8W; 4 at 1.9 mg/kg Q4W; 16 at 2.5 mg/kg Q4W; 13 at 2.5 mg/kg Q4W SPLIT).

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PMC11721295

For percentage positive cells – Ki67/ECAD, p-ERK/ECAD, CC3/ECAD, p-STAT3/PDGFR – we counted total nuclei and classified those that were positive for each individual stain as positive; all others were filtered out.

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PMC11618052

0.58 (hexane : ethyl acetate, 1 : 2, v/v).

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PMC9429973

The top procedure codes were for blood transfusion and Infusion Device into Superior Vena Cava.

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PMC5916734

The reduced dihydroquinone form of vitamin K (KH2 ) is converted to quinone 2,3-epoxide (K > O).

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PMC5025404

Currently, a large number of drugs based on these antibodies are available.

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PMC11307990

These DNA nanotapes show several advantages as a drug delivery system: (1) DNA nanotapes are well-defined nanostructures. (

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PMC11429241

TPP provides us with a unique opportunity in terms of bringing standardization to 3D cell culture generation.

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PMC11727000

A similar result was also observed in two independent neuroblastoma datasets (Primary NRC n = 283, TARGET n = 249; Figure S2).

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PMC11697189

The R package of RCircos was used to plot the copy number variation landscape of HSP genes in 23 pairs of chromosomes.

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PMC11055510

Subsequently, we found that in both SKOV3 and A2780 cells, RNase R treatment degraded the linear positive control (GAPDH) and MAN1A2, while circMAN1A2 was significantly resistant to the effects of RNase R (Figs. 1C and 1D).

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PMC9065483

according to the manufacturer’s protocol and quantified using a Nanodrop ND-1000 spectrophotometer (Thermo Fisher Scientific, Rockford, IL).

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PMC9532503

For example, even though rituximab therapy is considered as remarkable treatment option for non-Hodgkin’s lymphoma, 30–50% of patients still do not respond clinically or display resistance to re-treatment .

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PMC9429973

Of them, 19 patients were excluded (primary CNS lymphoma: n=5, no rituximab: n=3, only palliative therapy: n=5, bendamustin: n=1, RCHOP-21: n=2, death during prephase treatment: n=2, missing documentation: n=1).

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PMC7840816

Cell apoptosis was carried out using the Nucleosome ELISA kit.

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PMC9014716

Approximately 24 hours later, the cells were treated with prepared drugs for 48 hours.

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PMC11323699

CD47 expression was scored by H-score using QuPath software: staining intensity (0, + 1, + 2, + 3) × % cells positive (0 to 100) = 0 to 300.

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PMC8164677

Tetrazolium salt is cleaved only by active mitochondria of living cells.

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PMC11767725

The resultant hypoxic conditions activate hypoxia-inducible factor 1-alpha (HIF-1α) in keratinocytes and sebocytes, altering their metabolic activity.

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PMC11082662

Elevated SMPDL3B contributes to the proliferation, migration, and invasion of ovarian carcinoma cells. •

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PMC6034753

However, none of these proteins have demonstrated a conserved interaction motif, although the larger SH3 domain of Bcr-Abl1 and PI3-Kinase appear to be involved .

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PMC11001582

Following successful implantation, the cranial well was filled with warm sterile saline and the brain allowed to rest for at least 45 min before recordings.

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PMC11365983

Ethical approval was provided by the University of Alberta Health Research Ethics Board, with written informed consent received from all participants prior to their inclusion in the study.

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PMC11700247

CART-19 cells were generated from CD45.1 congenic mice, and the CD45.1 marker was used to track the adoptively transferred CART-19 cells.

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PMC8633974

mRNA loaded LNPs were formulated using non-turbulent microfluidic mixing using NanoAssmblr Ignite (Precision Nanosystem #NIN0001) using NxGen Cartridge (Precision Nanosystem #NIN0061) following manufacturer provided protocol.

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PMC11532793

Define the divided counts by .

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PMC9964654

Micelles at the same concentrations used in the assay without inoculum were also tested, as negative controls.

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PMC11757230

We first investigated the effect of cADSCs on the proliferation of canine hematologic malignancy cells in vitro.

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PMC9878562

Taken together, the data indicate that like in vitro lymphoma cells can also promote the migration of VAL-ko in vivo.

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PMC11746948

Sample sizes: (c, g, h, j, l, m) n = 3 independent experiments.

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PMC11684821

Biological datasets are presented in the Supporting Data Values file.

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PMC11190238

The entire landscape is featured with ridges and valleys indicating the barriers between each lineage and state with different intermediates to feature a plasticity spectrum.

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PMC11681005

Transcription factor binding activity (z) and expression (Exp) of HES1, HES4, ASCL1, ASCL2, SMAD4 and FOXA1 in normal cells, luminal cancer cells, basal cancer cells, and TPCS from scATAC data. (

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PMC10125312

To assess nanomaterial cytotoxicity, thiazolyl blue tetrazolium bromide (MTT) was used to determine the toxic potential of AuNR-PEG in cancerous and noncancerous cell lines of three different tissues.

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PMC9429973

Methods: The study included 80 DNA samples from AML patients admitted to the National Research Center for Hematology in 2019-2021 that were positive for NPM1 gene mutations detected by FA performed with the Nanophor-5 genetic analyzer (Synthol, Russia).

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PMC11683240

Subsequently, the experiment was performed as described in (B and C).

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PMC11656048

GPX4 oxidizes hydroperoxide and two molecules of reducing glutamate into lipid alcohols and oxidizing glutathione, acting as an antioxidant and free radical scavenger which can inhibit ferroptosis (Chen et al., 2022).

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PMC11525028

Data are presented as the mean ± SD.

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PMC11706297

Thin layer chromatography (TLC) was performed using silica gel 60 F254 aluminum sheets (Merck, Darmstadt, Germany).

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PMC11218145

Region of interest (ROI) was identified and quantified as total photon counts using Living Image software (PerkinElmer Inc, MA, USA) and expressed as photons/seconds/cm/sr.

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PMC11317131

Serine integrases catalyze the insertion of large DNA cargos at attachment (att) sites.

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