Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
 Community
1
PMCID
string
Sentences
string
ner
list
PMC11750712
The Merged Read Summary Report was used to identify the top merged read sequences and their frequencies to assess clonality.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "Merged", "Read", ...
PMC11082662
A,B) Western blot analysis revealed significantly higher protein levels of SMPDL3B in ovarian carcinoma lesions compared to adjacent nontumor tissues; n=20. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11629192
The patient developed more frequent seizure and Staphylococcus aureus pneumonia requiring invasive mechanical ventilation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "patient", "developed", "more", "frequent", "seizure", "and", ...
PMC11698348
A similar expression pattern was observed in skin at different time points of adolescent depilation-induced hair cycle, where elevated Elf5 expression was detected in anagen (D5-D12) and catagen skin (D18) compared to telogen skin (D0, **p value < 0.01; ***p value < 0.001, Fig 1c). (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7762347
Therefore, we aimed to evaluate cytotoxic and genotoxic activity of MCLR, CYN, and their binary mixture using the metabolically active human hepatocellular carcinoma (HepG2) cell line as experimental model.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11040965
cDNA was synthesized from total RNA using SuperScript IV VILO Master Mix (Thermo Fisher Scientific, #11766050) according to the manufacturer’s instructions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11742670
Table 1A sample of the collected dataset of the cell line A-375.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Table", "1A", "sample", "of", "the", "collected", "dataset", "of", "the", ...
PMC11695623
Mouse xenograft experiments in this study complied with the ARRIVE guidelines and were conducted in accordance with the U.K. Animals (Scientific Procedures) Act, 1986 and associated guidelines.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11675244
The “canonical” pathway , so-called due to its reliance on the key protein β-catenin, is well studied.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "“", "canonical", ...
PMC8633974
Subsequent stimulation of ACH2 T cells with TNFα induced viral rebound in control- and LTR-1/GagD-treated cultures but not in those receiving single- or dual TatD plus TatE treatments (Figure S9).
[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10858941
The dashed yellow square exemplifies the analysis area chosen for processing the images obtained.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "dashed", "yellow", "square", "exemplifies", "the", "analysis", ...
PMC11686380
One section from each brain was examined for control (n = 3), KD#1 (n = 7), and KD#1 + GAP43R (n = 6).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10203589
For example, with the activation of FGF18-FGFR2-c-Jun-YAP1 axis, the clinical prognosis of GC moves in an unfavorable direction (53); FGF18 promotes the proliferation of lung cancer cell lines and tumor formation in subcutaneous xenograft models through FGFR1-ERK pathway (127, 129); FGF18 promotes angiogenesis and tumor growth in HCC by enhancing FGFR3 pathway and phosphorylation of AKT-ERK protein, and is regulated upstream by Wnt/β-catenin signaling pathway (79).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8592717
Ginkgo biloba L [41-43] and Hypericum perforatum contain PCA; Pinellia ternata and Lilium lancifolium contain PAL.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ginkgo", "biloba", ...
PMC10812665
One example for such an approach is the characterization of screen hits in a cell migration assay .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "example", "for", "such", "an", "appr...
PMC6034753
Previous studies have shown that N and C-terminal regions of apoptin have important cell killing (apoptotic) activity and it is likely that Meq might be interacting with these N and C-terminal regions of apoptin to inhibit the apoptotic activity.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9509578
The elevated level of ROS downregulates the expression of MDR-associated protein 1 (MRP1), thus reversing MDR in A549R cells and in A549 tumor-bearing BALB/c mice model .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "B-CellLine", "...
PMC11723947
This pipeline also generates quality controls by running FastQC v.0.11.7 and Qualimap v.2.2.2.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "pipeline", "also", "generates", "quality", "controls", "by", "runni...
PMC11515150
Cytotoxicity of 12 C CAR-NK cells and NT-NK cells cultured with cytokine stimulation, IL-2 combined with IL-15, against CD5 malignant tumor cell lines was assessed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612315
c Representative proton-induced calcium influx at pH 5.5 under control conditions (blue) or with 1 µM exendin 9–39 (blue) or 1 µM BCTC (orange) pretreatment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7709199
This possibly indicates that the truncation of the glycans makes the proteins more sensitive to degradation, because the glycans cover a smaller area of the protein surface.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11699042
The aligned WGS data was used to estimate CNs with Allele-specific copy number estimation with whole genome sequencing (ACEseq) -algorithm as previously described.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11767817
PS is a negatively charged phospholipid located on the inner side of the cell membrane .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PS", "is", "a", "negatively", "charged", "phospholipid", "l...
PMC9429973
Further research is necessary in this field.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Further", "research", "is", "necessary", "in", "this", "field", "." ] } ]
PMC11317131
Helper plasmids encoding integrase variants (100 ng) and a flipper plasmid, pH1 EukFlip ZsGreen PhiC31 Hygro, containing ZsGreen flanked by attB and attP sites (500 ng) were transfected into 24-well plates seeded with HEK293T cells as described above.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11093197
Then, cells were transduced with RBsh lentivirus and subjected to selection with puromycin.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "cells", "were", "transduced", "with", "RBsh", "lent...
PMC11310713
The ovarian sex hormone (E2 and P4) levels that were reduced due to ovariectomy were restored through the injection of GTBs until the 12th week, reaching levels comparable to the ovary-intact rats.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11594806
When activated, AMPK initiates downstream pathways, including the phosphorylation of Raptor at S792, which is crucial for inhibiting mTOR during energy stress or low energy states (high AMP/ATP ratio) .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10006224
Clones were analyzed by immunoblotting with STAG1 and STAG2 antibodies to check protein elimination.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Clones", "were", "analyzed", "by", "immunoblotting", "with", "STAG1", ...
PMC11470999
When the tumor volume reached approximately 100 mm, the mice were randomly divided into three groups, with six mice per group, and treated twice a week with oral administration of PF (15 mg/kg), intraperitoneal injection of TMZ (40 mg/kg), or vehicle.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11626627
Wound-healing assays (H-I) and transwell assays (G, K) were performed in A498 cells transfected with pWPI+pLVTHM, sh-circATP2B1#1+pWPI, sh-TWIST1#1+pLVTHM, and sh-circATP2B1#1+sh-TWIST1#1 to validate the effects of circATP2B1 and TWIST1. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11463018
The combined solids were washed successively with H2O (100 ml), EtOH/MeOH (1:1, 100 ml), and Et2O (100 ml) and then dried under vacuum to afford the 13 as a white solid, 94.0% yield.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9583612
We outline a framework for doing so here and show initial results.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "outline", "a", "framework", "for", "doing", "so", "here", "and", "sh...
PMC7709199
Crystals of the receptor expressed in HEK293T cells looked like spherulites and did not diffract, while crystals containing the receptor with HEK293S MGAT1 glycans had a rectangular appearance and diffracted to a high-resolution limit of 4.5 Å; they could be indexed in space group I41, with unit-cell parameters a = b = 143.0, c = 139.2 Å. In order to further improve the X-ray diffraction quality of the crystals, we attempted to trim the glycans of the protein produced in HEK293S MGAT1 to the first GlcNAc residue by EndoH digestion.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11635087
Therefore, we concluded that the electron transport chain was functional, even in isolated chloroplasts.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "we", "concluded", "that", "the", ...
PMC11277157
Several systematic studies indicated the importance of the cell-type-dependent nature of sensitivity to siRNA by its length and its impact on gene expression related to the innate immune response.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11794568
By affecting the energy metabolism level of tumor cells, cell proliferation and migration were inhibited.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "By", "affecting", "the", "energy", "metabolism", "leve...
PMC11467964
Colony formation assay in SYO‐1. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Colony", "formation", "assay", "in", "SYO‐1", ".", "(" ] } ]
PMC10734950
Upon activation, caspases demolish key proteins and activate other enzymes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Upon", "activation", ",", "caspases", "demolish", "key", "proteins", "and", "activate", ...
PMC8992508
A few compounds showed moderate activities on P-gp but, interestingly, compound 71 showed a threefold higher inhibitory activity toward P-gp (IC50 = 0.434 μM) than cyclosporine A (IC50 = 1.21 M).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
D. Beauvais, M. Sourisseau, H. Béhal, S. Alfandari, N. Simon, E. Faure, I. Yakoub-Agha Centre Hospitalier Regional et Universitaire de Lille; Univ.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11708541
According to their research, CIH-induced changes in the hippocampal network and an increase in seizure was spontaneously reversed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "According", "to", "their", "resea...
PMC6024716
Lentiviral particles, three OAZ1 targeting lentiviral constructs, and CRISPR-Lenti non-targeting control transduction particles (Sigma-Aldrich # CRISPR12V, St Louis, MO, USA) were added the following day at a previously optimized multiplicity of infection (MOI) of 5, in 50 µL media and incubated overnight as above.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
44.2% had primary refractory disease or early relapse.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "44.2", "%", "had", "primary", "refractory", "disease", "or", "early", "relapse", "." ] } ]
PMC11635087
Z-stack images were captured at 0.2 μm intervals.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Z-stack", "images", "were", "captured", "at", "0.2", "μm", "intervals", "." ] } ]
PMC9429973
In vitro, oral-AZA like exposure resulted in decreased numbers of CD34+ CD38- LSCs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "vitro", ",", "oral-AZA", "like", "exposure", "resulte...
PMC5963610
One representative experiment out of three performed experiments is shown in each case.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "representative", "experiment", "out", "of", "three", "performed", "e...
PMC11063646
The analysis of variance (ANOVA) was employed to assess the significance of the quadratic models.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "analysis", "of", "variance", "(", "A...
PMC7057940
On the other hand, molecular analyses confirmed the initial suspicion of ES in both samples (patient 1 and 2), which showed expression of the EWS-FLI1 fusion gene, the molecular hallmark of ES.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11473843
Mice were maintained under a temperature of 21 °C + /− 2 °C, humidity 50% +/− 10% with a standard 12 h light/dark cycle and were fed ad libitum.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11541409
Under these conditions, co-targeting the metabolism pathway along with imatinib may have limited effectiveness.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Under", "these", "conditions", ",", "co-targeting", "the", ...
PMC10040136
MSC and GIST cells were isolated after 2–8 days of co-culture, and their mRNA and protein expression were examined.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MSC", "and", "GIST", "...
PMC10988555
The medium was changed by a medium with DMSO 0.1% (v/v) or the IC50 of complexes 2–4 and a scratch was made on the surface of each well.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11564405
A IHC images of RILPL2 expression and CD8 + T cell infiltration.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "IHC", "images", "of", "RILPL2", "expression", "and", "CD8", "+", "T",...
PMC11679326
SfL lectin isoforms from the seaweed Solieria filiformis, possessing great similarity to the OAAH family of lectins, have specificity to branched mannopentose oligosaccharides and exerted an anticancer effect on breast cancer MCF-7 cells .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11777207
The cells were harvested by gently pipetting at day 8 for downstream applications.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cells", "were", "harvested", "by", "gently", "pipetting", "at", ...
PMC11683240
B, E, and J, significance was tested using one-way ANOVA followed by Dunnett’s multiple comparison test and refers to samples treated with PT only (B, E, and J) (∗p < 0.1, ∗∗p < 0.01, ∗∗∗p < 0.001, ∗∗∗∗p < 0.0001, ns not significant).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11745600
wt, wild-type.
[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "wt", ",", "wild-type", "." ] } ]
PMC9429973
When tMZL was compared to tFL the most upregulated genes were CCR6, TBX21 and IFNG (all logFC ≥1.7, p<0.05) while MME was the most downregulated (logFC -2.6, p=0.012).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11306331
Source data provided as a Source Data file.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Source", "data", "provided", "as", "a", "Source", "Data", "file", "." ] } ]
PMC11332076
We next investigated in more detail the effects of F-iIR and F-iIGF1R on endogenous downstream signal transduction through immunoblot analysis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "next", "investigated",...
PMC11269933
However, its phosphorylation regulatory mechanisms mainly focused on human cancer research, with no reports in marine organisms.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "its", "phosphoryl...
PMC7812570
The expression levels were assessed by measuring the relative cell counts (A) and the fluorescence intensity (B) We next sought to characterize the resistance profiles of TZM-bl cells transduced with GPI-m36.4.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8751435
The detection wave was 260 nm.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "detection", "wave", "was", "260", "nm", "." ] } ]
PMC11095939
Right panel: quantification of Mecp2.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Right", "panel", ":", "quantification", "of", "Mecp2", "." ] } ]
PMC11423992
A significant reduction in tumor size was observed for all three strains of TFAB002s at doses of 3 mg/kg and 6 mg/kg, indicating a pronounced inhibitory effect on WIL2-S transplanted tumors (Fig 5B).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8916024
This variety has delicious meat and high nutritional value (e.g., protein exceeds 12%, fat is only about 0.6%, and it is rich in more than 40% of umami amino acids), and is favored by consumers and farmers in China (Zhou et al., 2021; Luo et al., 2021).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11544122
Because of the difficulty of determining this in cells, we addressed this by using phospho-peptides of the CXCR4 CT to precisely control site-specific phosphorylation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9221284
The 5′ and 3′ established regions allowed us to define PFull1, PFull2, and PFull3 primers (Figure 3B,C) to obtain the total cDNA and the structure of c-MYC mRNAs after sequencing.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11805741
The data suggested that the pigment has a dose-dependent cytotoxic effect on MDA-MB-231 cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "The", "data", "suggested", "that", "the", "pigment", "has", ...
PMC11243198
In these engineered NIH3T3 cells, the gene for firefly luciferase was stably integrated to be under the transcriptional control of Gli-responsive elements.
[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10530622
For instance, increased TGF-β I expression and deposition of collagen I and III, accompanied by increased excretion of oxalate and CaOx in urine, was reproducible in two models of hyperoxaluria, namely mice fed with hydroxy-L-proline, an oxalate precursor (Figure 1), and mice treated with ethylene glycol .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11670407
More interestingly, the loss of GPX4 function results in selective ferroptosis in vitro and prevents tumor recurrence in vivo since ‘persister’ cells acquire a dependency on GPX4 .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11674891
Collectively, these findings suggest that the GRPR-AKT-CRABP2/FNDC4 axis may serve as a promising therapeutic target in LUAD.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Collectively", ",", "these", "findings", ...
PMC9429973
The average haemoglobin at initiation of transfusion has remained relatively unchanged (69-78g/L), which is in line with NICE guidance.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11638255
b Flow cytometric analysis of neutrophil frequencies in NXS2 tumors after 1 week of TETA treatment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "b", "Flow", "cytometric", "analysis", "of", "...
PMC8956657
Significant reductions in nuclear import were observed for the R33A, R24A/R33A, RKR24/AAA24 (RKRA), and delta38 ORF4b constructs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Significant", ...
PMC11126803
D, chromatin immunoprecipitation (ChIP) assay results revealed that ERβ could bind to the ERE#2 located at the −1592nt to −1578nt bp from the transcriptional start site of ZEB1.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11015054
p < 0.001.
[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "p", "<", "0.001", "." ] } ]
PMC11240448
We included the following biochemical events into a description of the EGFR to ERK pathway (see Supplementary Figure S1: (1) EGF-EGFR interaction, (2) EGFR dimerization and autophosphorylation, (3) SOS recruitment to the plasma membrane by active EGFR, (4) RAS-GDP to RAS-GTP exchange by SOS, (5) RAF activation by RAS-GTP, (6) MEK phosphorylation by active RAF, (7) ERK phosphorylation by active MEK, (8) ERK phosphorylation on SOS and RAF that suppress activities of these proteins.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11359735
Lanes 1 and 9, molecular weight markers; lanes 2 to 4 and 6, blank; lane 5, immunoprecipitated CSP equivalent to 3.9 × 10 sporozoites; lanes 7 and 8, immunoprecipitated CSP equivalent to 1 × 10 and 5 × 10P.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11759543
This study reveals that caspase 8 plays a partial role in combined drug-induced apoptosis, and there are other pathways involved in the cell death mechanism.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10040136
The proportion of MSC was significantly higher in the drug-resistant group compared to the drug-sensitive group (D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "proportion", "of", "MSC", ...
PMC9429973
Our data highlight the need for novel CDK6 specific therapies targeting CDK6 sites not competing with INK4 or CIP/KIP binding to overcome therapeutic limitations.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11748335
D Average H3K27me3 intensity in the three groups of long LOCK regions and their surrounding regions for the NE2-KYSE450 pair.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "D", "Average", "H3K27me3", ...
PMC10047551
In this study, as expected, we found that stimulating NSCLC cell lines with IFN-γ induced PD-L1 mRNA expression.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this", "study", ...
PMC11615743
After being washed twice, the cells were analyzed with a flow cytometer (Beckman Coulter Life Sciences, Indianapolis, IN, USA), and 10 000 events were counted at a time.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9681981
By the proper concentration of these molecules, bacteria respond to these signals by activating different signaling pathways, altering gene expression, and modulating the physiological processes (Chen et al., 2014 ▶).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11240052
Under expression of circ-0008285 increases the apoptosis rate of the SKOV3 cell line. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "Under", "expression", "of", "circ-0008285", "increases", "the", ...
PMC11703992
Six genes with significant effects (IL32, ARHGAP15, RGCC, ARID5B, DDIT4, and TNFRSF25) were identified as significant exposures.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973
Summary/Conclusion: In the largest series reported so far for R-da-EPOCH in PMLBCL, FFP appeared somewhat but not impressively better than the expected with R-CHOP.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11001582
RAN translation occurs in every reading frame, encoding five potentially toxic DPRs: polyGA, polyGR, polyGP, polyPA and polyPR, which all form neuronal cytoplasmic inclusions in the brains of patients with C9ALS/FTD (refs. ).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10502403
Metabolites from unstimulated and stimulated NGMCs and NE1-GMCs were analyzed using a combination of capillary electrophoresis and Fourier transform mass spectrometry (CE-FTMS), and 357 metabolites (cationic:195, anionic:162) were detected (Figure 3A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Similarly, during the intensification phase, 19 out of 135 (14.1%) patients had VTE on L-ASNase while 10 out of 34 (29.4%) patients on PEG-ASNase developed VTE (p-value =0.014, OR= 2.94, 95% CI 1.21-7.13) after adjusting for age, sex, weight, and central line types.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11363012
Moreover, we show that natural products are often found in a wide range of concentrations across a population of cells, with some natural products at concentrations of over 100 mM per cell.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11770130
A one-column system was adopted for all analyses.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "one-column", "system", "was", "adopted", "for", "all", "analyses", "." ] } ]
PMC11547917
Even if these plants were forbidden by the US Food and Drug Administration and regulatory authorities of some countries , it is still used in the form of drugs or phytomedical preparations , especially in Asia , due to the beneficial effects of their short-term consumption .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11476106
HGs were maintained in the incubator for 1 h until complete polymerization, then 2 mL of supplemented culture medium (same as that for the 2D cultures) was added over each HG.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11594074
The level of significance was expressed as the p-value < 0.05 to show the difference between treatment with compound 4 and DMSO.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "level...
PMC8358176
Afterwards, the incubation (in CO2 incubator, at 37 °C, for 4 h) of plate was accomplished.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Afterwards", ...