Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
 Community
1
PMCID
string
Sentences
string
ner
list
PMC11762280
Dorsal skin samples were collected and immersed in Dispase II (2 mg/ml, Sigma-Aldrich, St. Louis, MO, USA) at 4 °C for 17 h to separate the epidermis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6102174
The bioassay on HepG2.2.15 cell line in vitro revealed that the water extraction of S. macrosperma showed activity inhibiting HBsAg and HBeAg with IC50 values of 0.22 (SI = 19.0) and 0.14 (SI > 30.0) mg/mL. Subsequent separation on this part provided eight new and 46 known compounds, seven of which showed anti-HBV potency.
[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
We used literature searches to identify previously reported cases of multiple solitary plasmocytoma.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "used", "literature", "searches", "to", "identify", "previously", "rep...
PMC9429973
High EVI1 expression has been suggested as marker of poor outcome in AML patients even without rearrangements of the EVI1 locus at 3q26.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "High", ...
PMC6133382
Based on positive lectin binding criteria, the 14 candidate cell lines were grown in 125-mL shake flasks (Fig 2).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Based", "on"...
PMC11352746
Based on this finding, we decided to focus our review on IncuCyte systems as a representative of live-cell imaging in neuroscience.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Based", "on"...
PMC9927933
To this end, we introduced a Deptor-KO mouse model by Cre-driven deletion of exons 6 and 7 of the Deptor allele, as previously described (24).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Human AML cell lines were studied in vitro for comparison.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Human", "AML", "cell", "lines", "were", "studied", "in", "vitro", "for", "comparison", "."...
PMC11696576
Table 1In vitro inhibitory activities and human plasma stability of GK470 analogscPLA2αGVIA iPLA2GV sPLA2Stability in human plasma% InhibXI(50)% Inhib% Inhib4 h20+ hGK470>900.011 ± 0.005864160.610.5.5¤GK40189404669.316.25¤GK420980.0016 ± 0.000204663.318.05GK419500298252.7GK427980.0010 ± 0.00017.54461.38.05GK403950.0014 ± 0.0001343221.5ND¤GK4401000.0010 ± 0.000103121.30.9*GK40279615079.747.3¤GK439970.0029 ± 0.0004675359.912.8*GK428940.0038 ± 0.0001543635.91.65GK449980.0017 ± 0.000567536318.35*The % inhibition of each enzyme is reported at 0.091 mole fraction (% Inhib).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11218145
Since the biological effects of TB are poorly known, in this work we departed from some hints of previous studies and investigated several hypotheses.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973
Patients with a PMR value of <43,48 were found to have a significantly longer PFS.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "with", "a", "PMR", "value", "of", "<...
PMC11745823
The RIT1 gene encodes a small GTP enzyme belonging to the Ras superfamily.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "RIT1", "gene", "encodes", "a", "small", "GTP", "enzyme", "belo...
PMC9429973
The data values at 24, 48, and 72 weeks have been annualized.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "data", "values", "at", "24", ",", "48", ",", "and",...
PMC11046454
As expected, target cancer cells could be effectively eliminated by i-AptPTK7-CAR-T only in a TME-mimic acidic environment (Figure 4F).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "expect...
PMC10297204
The efficacy of adjuvant ethanol therapy has sometimes been applied in the field of bone and soft tissue tumors .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "efficacy", "of", "adjuvant...
PMC11774747
Allogeneic CAR-T are derived from “treatment naïve” healthy donors, allowing for the generation of “off-the-shelf” products that can be prepared in advance and made readily available, with a significant reduction of the time from diagnosis to treatment (3).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11190238
The proper organization these cell-cell adhesion in epithelial cells is guided by apical-basal polarity.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "proper", "organization", "these", "cell-cell", "adhesion", "in"...
PMC11583010
ETx-22 was detected with rabbit anti-human IgG which was revealed with a secondary anti-rabbit IgG coupled to HRP and a ChromoMap DAB kit.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ETx-22"...
PMC6642070
In addition, knockdown of endogenous p53 increased the luciferase signal (Fig. 5c).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "knockdown", "of", "endogenous", "p53...
PMC8711270
AdV production might be preferred in these cell lines over HEK293 due to the decreased risk of accidental RCV formation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "AdV", "production", ...
PMC9388315
Ras, raf, ERK, and the MAPK pathway are all activated by ErbB2.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ras", ",", "raf", ",", "ERK", ",", "and", "the", ...
PMC11224020
HeLa Kyoto EMBO cells were cultured in DMEM supplemented with 10% FBS and 1% penicillin–streptomycin.
[ { "tags": [ "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HeLa", "Kyoto", ...
PMC10606998
The number of the cells was estimated on a LUNA-II™ Automated Cell Counter (Logos Biosystems, Anyang-Si, Republic of Korea) after mixing the cell suspension with trypan blue (1:1).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11629461
Immunocytochemistry with confocal imaging confirmed that DUOX2 was present in the plasma membrane and cytosol in SW579 cells (Figure 5B) but no fluorescence was seen in the absence of the primary antibody (Figure 5A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11468365
It used the full omics data of cell lines and the chemical descriptor for drugs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "used", "the", "full", "omics", "data", "of", "c...
PMC10114490
PD100-110) and PD125 of P3G4 clone are depicted in Additional file 1: Fig. S4 Robust induction of the hepatocyte program in iHDF-T. iHDF-T maintain inducibility after more than 80 population doubling without losing hepatic phenotype in diHLC-T. A Volcano plot of all genes expressed in PD and PD diHLC-T (three replicates each) by RNAseq.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10114490
Bioanalyzer’s RQN values were at least 9.9 for all RNAs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Bioanalyzer", "’s", "RQN", "values", "were", "at", "least", "9.9", "for", "all", ...
PMC10858941
Figure 2) and the drug’s effect on p62 was more clearly visible.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Figure", "2", ")", "and", "the", "drug", "’s", "effect", "...
PMC8316344
A, B TRIB2 knockout increased while TRIB2 overexpression decreased TFRC expression.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", ",", "B", "TRIB2", "knockout", "increased", "while", "TRIB2", "overexpressio...
PMC9596868
Protein lysates were processed and analysed by Western blotting.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Protein", "lysates", "were", "processed", "and", "analysed", "by", "Western", "blotting", "." ] } ]
PMC8633974
Electroporation did not adversely impact cell vitality (Figure 7d and S11).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Electroporation", "did", "not", "adversely", "impact", "cell", "vitality", ...
PMC9429973
The majority of the patients(41%) belonged to ELN intermediate risk group.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "majority", "of", "the", "patients(41", "%", ")", "belonged", "...
PMC10495912
A genetic algorithm was used to implement the docking and a maximum of 200 runs was considered.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "genetic", "algorithm", "was", "used", ...
PMC9429973
Results: All pts successfully engrafted.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "All", "pts", "successfully", "engrafted", "." ] } ]
PMC11705484
Density distribution of mA peaks across mRNA transcripts. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Density", "distribution", "of", "mA", "peaks", "across", "mRNA", "transcripts", ".", "(" ] } ]
PMC11756514
The WTA is anchored to the peptidoglycan layer through a covalent linkage unit with glycerol phosphate and a ManNac-GlcNAc unit.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "WTA", "is", "an...
PMC11783017
In addition, the rheological properties of the hydrogels were investigated to verify the injectable property.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "the", "rheological", "propertie...
PMC11180402
These results indicate that SNHG1 reverses ISO-mediated inhibition of BMIBC cell invasion and anchorage-independent growth by modulating the levels of MMP-2, MMP-9 and PTEN.Fig.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC11569208
Top hits from the high-throughput siRNA phosphatase screen.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Top", "hits", "from", "the", "high-throughput", "siRNA", "phosphatase", "screen", "." ] } ]
PMC9429973
For EFS, age (HR: 1.19; P=.002), WBC (HR: 1.30; P=.028), and FLT3-ITD (HR: 1.83; P=.003) were unfavorable, whereas NPM1 (HR: 0.65; P=.028) and HCT (HR: 0.33; P<.001) were favorable.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11098378
We then used limited proteolysis to produce a core Ceg10 central domain (T55-R287) that was amenable to structural determination by crystallography (Fig 4A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Aims: We investigated the role of the phosphatidic acid phosphatase LPIN1 in AML and healthy hematopoietic cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "We", "investigated", "the...
PMC11319300
ChIP-seq for H3K4me1, H3K4me3, and H3K27ac histone modifications in CH12 mouse B cell lymphoma cell line, adult liver cells, lung cells, and bone marrow, alongside CTCF from B cells, were retrieved from ENCODE (ENCODE Project Consortium et al., 2020), see Supplementary Table S1.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9841531
The reference MCT1 inhibitors 7 and 8, as well as the most potent lead MCT1 inhibitors 24 and 30, were visualized by applying ChemDraw professional 17.1 and stored in mol file format.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10606998
Glioma cells were irradiated with increasing doses of 0, 0.5, 1, 2, 4, and 6 Gy at the proton Bragg peak.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11792740
Modifying the TME through strategies such as inhibiting immunosuppressive cytokines or depleting Tregs and MDSCs has demonstrated potential in enhancing T-cell function.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Modifying", ...
PMC11495567
was purchased from Sigma Aldrich (Burlington, MA, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "was", "purchased", "from", "Sigma", "Aldrich", "(", "Burlington", ",", "MA", ...
PMC11657744
Data are reported as means ± SD of three independent experiments.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "reported", "as", "means", "±", "SD", "of", "three", "independent", ...
PMC11463018
19 potently inhibited HDAC1 with an IC50 of 25.4 nM, even though it was 6∼fold weaker than HDAC6.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "19", "potently", "inhibited", "HD...
PMC8633974
All the conditions in each cell line were ran in biological triplicates.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "the", "conditions", "in", "each", "cell", "line", "were", "ran", "i...
PMC7057940
On the other hand, H3K27ac proved to be an abundant modification in the region amplified from the A673 cell line, and was also found in patient 1, providing evidence for its possible role in EWS-FLI1 fusion gene activation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
According to the correlation analysis, we found that IDH1/2 and complex karyotype (CK) or ZBTB7A mutation, ASXL2 and CCND2 mutation, t (x; 8; 21) abnormality and JAK2 or FLT3 mutation may co-mutate.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
There were 2 (6%) second primary malignancies and one patient (3%) experienced grade 3 neuropathy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "were", "...
PMC3164356
Figure 3A global view of the expression of CHO-K1 glycosylation genes.(a) While homologs were identified for 99% of the human glycosylation-associated transcripts, only 53% had detectable expression.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10968586
In vitro, treatment of promyelocytic leukemia cell line HL-60 with 50–100 μM HT reduced cell viability and triggered apoptosis, as indicated by the cleavage of PARP, the activation of caspase-3, and cytochrome c release .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11802855
A The volcano plot of the differentially expressed genes revealed by RNA-seq profiling of the CXCL7-OE and NC RPMI8226 cell lines (|logFC | > 1, p < 0.05).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", ...
PMC11489175
Pharmacological inhibitors of USP1 such as SJB3-019 and pimozide have been reported to reduce cisplatin-induced Snail expression in ovarian carcinoma cells similarly to what is observed upon USP1 knockdown 80.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O"...
PMC11438317
Cells were then processed for immunofluorescence to detect the localization of LYP and SLP76.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "then", "processed", "for", "immunofluorescence", "to"...
PMC8270637
Immunoglobulin G was used in the reaction as a negative control.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Immunoglobulin", "G", "was", "used", "in", "the", "reaction", "as", "a", "negative", ...
PMC5034105
Similarly, DENV-2 infection also caused increased mean viral load and DENV-2-NS1 protein expression without inducing CPE in HEK cells, and viral RNA might be detected in urine of dengue patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11720808
Scutellarein (SCU) is a monomeric flavone bioactive compound with potent anti-cancer activity.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scutellarein", "(", "SCU", ")", "is", "a", "monomeric", "flavone...
PMC11618052
Yield: 0.29 g (77%), white solid, m.p: 146–148 °C, Rf.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Yield", ":", "0.29", "g", "...
PMC11802855
Lentiviruses carrying CXCL7-overexpression (CXCL7-OE) and Normal-Control (NC) were used to infect NCI-H929 and RPMI 8226 cell lines.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "I-CellLine", "O", "O", "O" ], "tokens": [ "Le...
PMC10944868
The binding orders and the protonation states of residue were corrected.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "binding", "orders", "and", "the", "protonation", "states", "of", "residue", "w...
PMC11640247
For the analyses of axon elongation in hippocampal neurons and cortical neuron migration (Figure 4A,C), 15–20 optical Z-stack confocal images (0.42 μm intervals) and 3–4 images (27 μm intervals) were obtained, respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11727145
There is currently a need to work with biological assays to screen and determine the mechanistic actions of cutaneous cellular therapies.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "is", "cu...
PMC11092418
Therefore, in this study we examined the effect of different CDK inhibitors on the growth of brain cancer cell lines when used alone or in combination with the irreversible pan-HER inhibitor neratinib.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11634027
For Ds:V5 expressed by ds, which provides enhanced Ds activity, protein levels appeared increased relative to ds (Fig. 3D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11791478
Thrombin generation was initiated by adding calcium and a thrombin-specific substrate.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thrombin", "generation", "was", "initiated", "by", "adding", "calcium", "and", "a", "...
PMC11762280
E Representative images of MPO, MMP9, and F4/80 immunohistochemical staining in Ac-DEVD-CHO or PBS treated mice after UVB irradiation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "E", "Representative", ...
PMC11407042
Thaw Fetal Bovine Serum (FBS) in the preheated water bath.c.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thaw", "Fetal", "Bovine", "Serum", "(", "FBS", ")", "in", "the", "preheate...
PMC11675244
Mutations in the APC gene appear in nearly 85% of sporadic intestinal cancer cases .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mutations", "in", "the", "APC", "gene", "appear", "in", ...
PMC11718274
In A-431 cancer cells exposed to Y2O3NPs for 72 h, this mitochondrial damage was evident from the dramatic loss of mitochondrial membrane potential.
[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "token...
PMC11731161
Once the average tumor size reached 100 mm, the mice were randomly divided into four groups and treated with PBS, DOX (0.25 mg/ml, administered via drinking water), SEL (10 mg/kg, administered via gavage), or a combination of DOX and SEL for the duration of the experiment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9688728
The third group (Figure 5c) of 22 metabolites demonstrates noticeable zigzag fluctuations in the first 15 days, with higher levels at the final stages.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
No apparent relationship between dose-exposure-response and G3/4 thrombocytopenia or neutropenia was observed across all doses, whereas a correlation between dose-exposure-response and incidence of infusion-related reactions across the 0.4–6 mg/kg Q3W and Q4W dosing cohorts was found.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10198699
From this sample, Gey’s laboratory assistant isolated the cancer cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "From", "this", "sample", ",", "Gey", "’s", "laboratory", "assistant", "isolated"...
PMC9429973
A. Romano, G. Scandura, D. Tibullo, A. M. Amorini, E. La Spina, A. Barbato, C. Giallongo, C. Cerchione, G. Simonetti, G. Martinelli, F. Di Raimondo Dipartimento di Chirurgia e Specialità Medico Chirurgiche; DIPARTIMENTO DI SCIENZE BIOMEDICHE E BIOTECNOLOGICHE; DEPARTMENT OF MEDICAL, SURGICAL SCIENCES AND ADVANCED TECHNOLOGIES, Università degli Studi di Catania, CATANIA; IRCCS Istituto Romagnolo per lo Studio dei Tumori “Dino Amadori” - IRST S.r.l.,
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11411131
The SECIS was derived from TrxR1 gene.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "SECIS", "was", "derived", "from", "TrxR1", "gene", "." ] } ]
PMC11321678
Notably, the core regulatory circuitry constructed in our study drives subgroup‐specific gene expression, uncovering positive TF regulators that were not detected by transcriptional analysis alone.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7081114
Correlation between KIF21B expression and clinicopathological characteristics P < 0.05 was considered significant, P < 0.05, P < 0.01; Statistical analyses were performed using the χ test.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9031474
Only the dialdehyde drimanes polygodial (2), warburganal (24), and mukaadial (25) showed a strong cytotoxic activity.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11228511
Progerin expression changed the structure of the lamin B1 meshwork (Fig. 2 A and B), resulting in irregularities and large openings that mirrored the abnormalities in the progerin meshwork, as judged by confocal (Fig. 2A) and STED (Fig. 2C) microscopy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10529414
The RUNX1 TF is essential for hematopoietic cell differentiation .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "RUNX1", "TF", "is", "essential", "for", "hematopoietic", "cell", "differentiation", "." ] } ]
PMC8382973
The information could be obtained by referring to the Kyoto Encyclopedia of Genes and Genomes (KEGG) Orthology class 1 and class 2 functional gene classes to obtain the functional composition of the predicted genome (49).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11488203
n = 3) Solid tumors can develop as an organ-like structure whereby cancer cells constantly interact with multiple other cell types of the tumor microenvironment such as immune cells and MSC .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Summary/Conclusion: Cytokine release, T-cell activation, BM infiltration, and MM cell depletion are early PD changes seen after treatment with RG6234 and precede clinical responses.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11347429
Of the six DEGs from the comparison of infected African-American versus Caucasian patients, four DEGs (SMIM1, FBXO39, HES4, and HP; Data file 28 and Data file 13 ) also exhibited a significant cis-eQTL ( Supplementary Figure S3A ) stratified by ethnicity; Supplementary Figure S3B stratified by genotype; Data file 14 ).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11684269
Perturbation of immune homeostasis can lead to the development of a broad spectrum of diseases, such as infection, chronic inflammation, metabolic disease, and cancer (2–6).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11088135
In addition, lncRNA NEF could inhibit glioma progression by downregulating TGF-β1 expression .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "lncRNA", "NEF", "could", "inhibit", "glioma", ...
PMC7305184
While effect of different pulse parameters on cells and tissues are being addressed in in vitro and in vivo experiments, not much is known about the impact of repeated treatment, i.e. if cells can adapt to PEF treatment in a way that they would become less affected by the PEF treatment, i.e. if the treatment would become less efficient when repeated.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11760643
Numbers of immune cell subsets were assessed using FlowJo software version 10.7.1.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Numbers", "of", "immune", "cell", "subsets", "were", "assessed", "using", "FlowJ...
PMC11680578
A minimum of 10 cells were used to extract RNA.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "minimum", "of", "10", "cells", "were", "used", "to", "extract", "RNA", "." ] } ...
PMC11531744
The formula mentioned above was used to calculate the risk score, and patients were divided into two groups with the same cutoff.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC9812014
6-O-Butanoyl castanospermine (B-CAST) alkaloid is a castanospermine alkaloid derivative that has been assessed for its anti-HIV activity via different In vitro experiments.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11674891
We found that GRPR overexpression led to a significant increase in the transcription and protein levels of both genes (Figure 4c), and GRPR knockdown weakly but significantly reduced both gene expressions (Figure S1a,b).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11539788
According to the KEGG enrichment analysis, these DEGs related to RNF19A were significantly enriched in neuroactive ligand‒receptor interaction, the mTOR signalling pathway, the oestrogen signalling pathway, the cAMP signalling pathway, and the calcium signalling pathway (Fig. 4B).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6114978
MST1 expression is decreased at the RNA level in 5 of 12 sarcoma cell lines (42%).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MST1", "expression", "is", "decre...
PMC5600151
In a different approach, Wang and collaborators used branched PEG (bPEG) conjugated with G2 PAMAM (PSPG) through disulfide linkages (cleavable by intracellular glutathione) to encapsulate DOX and siRNA against B-cell lymphoma 2 (Bcl-2) .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11087055
J-K’’’) Vorticity plots, displaying averaged measure of the local rotation during each time period.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "J-K", "’’", "’", ")", "Vorticity", ...