OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC8270637	PD-1, NFATc1, lamin B, and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) antibodies and anti-mouse/rabbit secondary antibodies for Western blot were purchased from Proteintech Group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11732523	Given the patient's limited response to two prior antiviral treatment for COVID-19, a third round was not pursued.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Given", "the", "patient", ...
PMC11792766	The cells underwent hypotonic treatment as outlined by Heger et al. (2018), were fixed on glass slides, and stained with GelRed nucleic acid stain.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5673955	Cytotoxic activity of RrA was tested in 72 h of incubation with Jurkat cells or normal CD4 T lymphocytes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cytotoxic", "activity", "of", ...
PMC8984067	Test conditions were as follows: scanning range: 200 nm–1100 nm; slit width: 2.0 nm, and sampling interval: 0.5 nm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC3035438	The selected samples of culture supernatants were first serially diluted in fresh culture medium and titrated by anti-apoferritin ELISA as above to determine the dilution required to obtain a maximal signal of O.D. = 0.7.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11680049	Before being introduced into in vitro culture, the primary explants underwent a stepwise sterilization process.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Before", "being", "introduced", "into", "in", "vitro",...
PMC11659921	The CNV information of angiogenesis and stemness‐related genes in OV. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "CNV", "information", "of", "angiogenesis", "and", "stemness‐related", "genes", "in",...
PMC11768281	Additionally, the IL-27R receptor has been identified as a critical regulator of IL-10 production, further modulating T-cell responses during malaria infection .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additio...
PMC11653533	Moreover, the bark utilized as an astringent, love potion, antibacterial against Staphylococcus aureus and Escherichia coli, and to treat gonorrhea, loose bowels, dysentery, hemorrhoids, gastrohelcosis, inflammation, burns, scabies, hiccup and heaving; leaves utilized in asthma, cough, sexual disorders, the runs, haematuria, toothache, migraine, eye troubles, gastric issues, scabies, tuberculosis, fever, loss of motion and hemorrhoids; fruits utilized in problems related to asthma, purgative, digestive, tuberculosis, fever, paralysis and hemorrhoids; latex used in neuralgia, inflammations and hemorrhages (Makhija et al., 2010).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11707832	Recurrent infections represent a predominant clinical feature observed in α-mannosidosis cases, as documented in prior literature .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Recurrent", "infections", "represent", "a", "pred...
PMC11301095	Continuous video EEG monitoring failed to detect brain waves.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Continuous", "video", "EEG", "monitoring", "failed", "to", "detect", "brain", "waves", "." ] } ]
PMC11775197	Previous reports have shown that the PPARγ agonist troglitazone inhibits colon cancer metastasis by inhibiting matrix metalloproteinase-7 (MMP-7) synthesis and the adhesion of extracellular matrix (ECM) proteins .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11252553	Due to its potential to mitigate radiation-induced lymphopenia with lower toxicity, Taurine is considered a valuable candidate for pre-treatment in radiation therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Due", ...
PMC2196094	RMCP-2 and the three closely related proteases of the RMCP-8 subfamily were identified as the major mucosal MC proteases in rat.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RMCP-2", "and", "...
PMC8481254	We found that STZ induced CDK19 expression in transplanted tumor tissue, while CA reduced the increase in CDK19 expression induced by STZ (Fig. 3E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9776316	No.: 2197), ATM (Cat.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No.", ":", "2197", ")", ",", "ATM", "(", "Cat", "." ] } ]
PMC8996378	The first-generation reversal inhibitors include calcium channel blockers, immunosuppressants, protein kinase C inhibitors and so on.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "first-generation", "reversal", "inhib...
PMC11473843	Cells were then washed with staining buffer and resuspended in 200 μL Propidium Iodide (PI) at a final concentration of 4 μg/mL (A427), 20 μg/mL (A549) or 40 μg/mL (HBEC3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", ...
PMC10523483	Human fetal lung fibroblast cell line MRC5 was cultured in MEM medium (Cytiva).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Human", "fetal", "lung", "fibroblast", "cell", "line", ...
PMC9429973	Peri-CAR-T checkpoint blockade may ameliorate tumor-intrinsic resistance mechanisms.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Peri-CAR-T", "checkpoint", "blockade", "may", "ameliorate", "tumor-intrinsic", "resistance", "mechanisms", "." ] } ]
PMC10589262	The fate of membranous MT-KIT was tracked in a time-dependent manner to understand its role in GIST tumorigenesis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "fate", "of", "membranous", "MT-...
PMC10588957	AMPK promotes autophagy via phosphorylation (25).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "AMPK", "promotes", "autophagy", "via", "phosphorylation", "(", "25", ")", "." ] } ]
PMC9429973	Aims: To evaluate the associations of TCR repertoire and its diversity with asparaginase hypersensitivity in children with ALL.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "To", "evaluate", ...
PMC11682224	CHD1L promotes the expression of PD-L1 in cutaneous squamous cell carcinoma cells and promotes M2 polarization in TAMs. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CHD1L", "promotes", "the", "expre...
PMC11604830	A further in vivo experiment was conducted involving the intravenous injection of PFCE‐NE in a model of acute neuroinflammation (see Data S1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC5173112	Intriguingly, we found that there was significant difference in mRNA expressions of IL-8 gene between control and USP21 siRNA RCC cells lines (Figure 6A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11772585	A, B Metabolic phenotypes of HSC-1 and A431 cells were determined by the both OCR and ECAR assays (n = 5).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], ...
PMC11632064	Oxygen consumption rate in Rho-0 cells and parental controls (MeWo).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Oxygen", "consumption", "rate", "in", "Rho-0", "cells", "and", "parental", "cont...
PMC11643361	The development of effective cancer therapeutics remains one of the most significant challenges in modern medicine, with researchers continuously seeking novel approaches to target cancer cells while minimizing damage to healthy tissues.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11082662	Furthermore, the evidence suggests that elevated SMPDL3B contributes to the proliferation, migration, and invasion of ovarian carcinoma cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O" ], "tokens": [ "Fu...
PMC11400680	In this study, we use an open-source dataset called Expert Visual Cell Annotation (EVICAN) (4) for the experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC11098378	Understanding bacterial effector function is important because these proteins can be critical drivers of bacterial pathogenesis .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Understanding", "bacterial", "effector", "function", "is", ...
PMC9473868	In summary, BAI inhibited FLS proliferation and EMT, whereas induced cell apoptosis through blocking the PI3K/Akt/mTOR pathway, supporting clinical application for RA progression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC4360730	Details and references for the requested additions are also submitted to ontology specific issue trackers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Details", "and", "references", "for", "the", "requested", "...
PMC9429973	All patients had parenchymal disease and all received bridging therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "patients", "had", "parenchymal", "disease", "and", "all", "received", "bridging", "therap...
PMC11791203	The values are expressed as mean ± SEM (n = 6).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "values", "are", "expressed", "as", "mean", "±", "SEM", "(", ...
PMC8728081	Furthermore, we have assessed the toxicity of Kajjali and Rasasindura in NIH3T3 cell lines and zebrafish larvae.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "we", "have", ...
PMC10747139	However, no cytotoxicity study was reported on healthy cell lines, and IC50 values were reported for standard drugs for comparison.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",...
PMC9429973	The accuracy of nomograms was verified by high concordance index and good agreement with the predicted value in calibration plots.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "accuracy", "of", ...
PMC11682172	The numbers of identified proteins for each cell line are shown in Table 1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "numbers", "of", "identified", "proteins", "for", "each", ...
PMC9509578	The results show increasing interest in the nanomedicine approach to overcome MDR in cancer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", "show", "increasing", "interest", "in", "the", ...
PMC11724582	The following antibody dilutions were used: anti-GAPDH (1:10000, ABclonal), anti-αSMA (1:4000, Proteintech), anti-FAP (1:1000, ABclonal), HRP-conjugated secondary antibody (1:10000, ABclonal), anti-YAP/TAZ (1:1000, CST), and anti-GAPDH (1:50000, ABclonal).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	With a median follow-up of 9.5 months (range 0.3-78.3), 3-years OS was 64% for patients with concurrent RS, 53% for untreated RS patients and 5% for treated RS patients (Figure; p<0.01).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11487720	We established stable transfectants of L929S cells expressing EGFP-TRAF2(124–233), ECFP-TRAF2, ECFP, or EGFP (Fig. 6B).	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "establis...
PMC11787355	and Xylazin, 10 mg/kg i.p.)	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "and", "Xylazin", ",", "10", "mg/kg", "i.p", ".", ")" ] } ]
PMC11488203	Interaction of MSC with cancer cells either by direct cell-to-cell communication or by indirect processes including the release of EVs/exosomes has been studied previously .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	Aims: Better understanding of relapse biology could improve treatment efficacy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "Better", "understanding", "of", "relapse", "biology", "could", "improve", ...
PMC9429973	C. Wang, J. Liu, H. Lei, Y. Li, J. Wu, B. Guo, R. Hu, T. Liu, J. Wu, Y. Ding, C. Hu, S. Liang, C. Xiao, X. Liang, D. Huang, T. Yang, W. Zhang, Z. Yang, J. Li, Y. Nan, Q. Li, Y. Xiang, Y. Wu, Y. Liu Hematology; Chongqing University cancer hospital, Chongqing, China Background: HIV-associated lymphoma is the most common subtype of HIV-associated cancers, with a very low incidence.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11470381	Add 0.1 µg/mL of recombinant SDF1α (diluted in imaging medium, see Recipe 8) to the dish 10–15 min prior to acquisition during incubation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11420784	C, Colocalization of LC3 and galectin-3 with UPEC in 5637 cells at 4 hpi.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ "C", ",", "Colocalization", "of", "LC3", "and", "ga...
PMC11766332	MicroRNAs (miRNAs) play a role in ASD and may influence metabolic pathways.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MicroRNAs", "(", "miRNAs", ")", "play", "a", "role", "in", ...
PMC11612315	To determine the subtype selectivity of exendin 9–39, we tested its effect on TRPA1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "determine", "the", "subtype", "selectivity", "of", "e...
PMC10530622	These effects were blunted by treatment with or overexpression of bone morphogenic protein-7, which is an anti-fibrotic cytokine in the kidney .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "eff...
PMC11321678	Charles et al. analyzed the enhancers and super‐enhancers that are differentially regulated in MB subgroups and found that they recapitulate and extend the transcriptional and phenotypic features of these subgroups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11676670	Plasmid pTagRFP-C-SRSF2 was kindly gifted by Dr. Marat S. Pavlyukov.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Plasmid", "pTagRFP-C-SRSF2", "was", "kindly", "gifted", "by", "Dr.", "Marat", "S.", "Pavlyukov",...
PMC11201245	The BAC clones RP11-17M8, RP11-347C14, RP11-449D3, RP11-911D14, and RP11-122H7 are homologous to 8q24.33 and are labeled with Green-dUTP (Enzo Life Science, NY, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11758416	Add 120 μL of 1X Trypsin-EDTA to wells of culture plate and mix thoroughly.f.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Add", "120", "μL", "of", "1X", "Trypsin-EDTA", "to", "wells", ...
PMC11629192	We assessed the therapeutic potential of OFA in five pediatric anti-NMDAR encephalitis patients who showed poor responses to the first-line immunotherapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "assessed", ...
PMC8358176	After 24 h and the replacement of culture medium with a new one, MTT working solution (10 μL; 5 mg/mL in PBS) was transferred to each well.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11409031	In breast cancer, a model based on CD8 T cells is significantly associated with clinical outcomes and the sensitivity to treatment .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "breast...
PMC11638288	In summary, NKp46 ILCs play a pathogenic role in neuroinflammation, and they represent potential targets for treating inflammatory disorders of the central nervous system .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10858941	Accumulation of p62 is reduced in hypoxia compared to normoxia, which is consistent with its increased degradation in hypoxia .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Accumulation", "of", "p62", ...
PMC11747949	Therefore, to improve osteosarcoma treatment outcomes, a better understanding of osteosarcoma biology is needed with a focus on macrophage/monocyte biology and hypoxia.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11394730	Targeting glucose metabolism as a therapeutic method in cancer treatment has a biological basis in the differences in energy metabolism between normal and cancerous cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC7433824	We identified 8 and 31 unique proteins in U87 cell lines treated with 100 and 300 µM P4, respectively (Table 2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "token...
PMC9429973	All patients had the diagnosis of absolute erythrocytosis with moderate hyperleukocytosis and thrombocytosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "patients", "had", "the", "diagnosis", "of", "absolute", "erythrocyto...
PMC11536589	It has been documented that the existence of a positive feedback loop between the long non-coding RNA (lncRNA) PVT1 and the Wnt/β-catenin signaling pathway, which played a role in the development of gemcitabine resistance in human pancreatic cancer (Zhou et al. 2020).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11360263	These clinical HCMV strains displayed oncogenic and stemness features when cultivated on HMECs and OECs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "clinical", "HCMV", "strains", "displayed", "oncogenic", ...
PMC6450504	At a fixed concentration of siRNA not fully complexed, the size of the nanosystem increased, and the ZP decreased due to the presence of excess/free nucleic acid and incomplete condensation of the bPEI-chains.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9024365	All constructs contain an in-frame HA tag at the N-terminus for detection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "constructs", "contain", "an", "in-frame", "HA", "tag", "at", "the", ...
PMC9509578	QDs generate intracellular ROS, thereby causing cancer cell death through oxidative DNA damage .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "QDs", "generate", "intracellular", "ROS", ",", "thereby", "causing", ...
PMC11188874	E, Effect of WT and mutant HDAC6 on co-immunoprecipitation of HR23B.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "E", ",", "Effect", "of", "WT", "and", "mutant", "HDAC6", "on", "co-immunop...
PMC11549062	Endosome and lysosome trajectories of cos7 cells with the treatments of PDGFR‐β inhibitor and overexpression, and PTP1B inhibitor or RNA knockdown. (	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10605143	We postulate that HSF1 may be involved in the remodeling of the mammary gland architecture over the female lifetime, as well as the acquisition of invasive cancer cell phenotype.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11590005	The ideol-ogy of meritocracy which has become established in Brazilian society intersects with racism to maintain hierarchical racial positions .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "ideol-ogy", "of", "meritoc...
PMC9966931	Figure 1 depicts some of the bioactivities exhibited by each compound described above and the modes of action by which they are exerted .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Figure"...
PMC7342409	For the imatinib group, imatinib mesylate capsule powder was dissolved in a 15 mg/mL working solution with normal saline.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "the", "imatinib", ...
PMC11670407	Our results demonstrated that OTULIN expression was significantly upregulated in OS tissues and cell lines following cisplatin treatment but not in response to doxorubicin or methotrexate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973	Cohort B enrolled pts who had early relapse after initial therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cohort", "B", "enrolled", "pts", "who", "had", "early", "relapse", "after", "initial"...
PMC11116779	The maximum effect was recorded after treatment with 500 μg/mL PS-NPs for 48 and 96 h, when A549 viability was reduced by 21 and 22%, respectively (Figure 1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", ...
PMC9024365	Neurons were blocked with 10% BSA for 30 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Neurons", "were", "blocked", "with", "10", "%", "BSA", "for", "30", "min", "." ] } ]
PMC11740399	Various ratios of 3025@ML from 1:1 to 1:20 (w/w) (SRT3025:ML) were synthesized to determine the drug loading capacity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Various", "r...
PMC11347429	Thus, it may have a function in the host’s defense against infections (GeneCards).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "it", "may", "have", "a", ...
PMC8143558	Other phytochemicals such as alkaloids, or interactions between phytochemicals, may be responsible for some observed and reported antimicrobial activity in plants.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Other",...
PMC7602170	Activated mTORC1 also activates Hypoxia-inducible factor 1-α (HIF1-α) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Activated", "mTORC1", "also", "activates", "Hypoxia-inducible", "factor", "1-α", "(", "HIF1-α", ...
PMC4360730	As assays are not added to the ENCODE project regularly, we anticipate only 1–2 new term request for an assay per year.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", ...
PMC7812570	C Inhibition of cell-cell HIV-1 transmission by GPI-anchored antibodies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "C", "Inhibition", "of", "cell-cell", "HIV-1", "transmission", "by", "GPI-anchored", "antibodies", "." ]...
PMC9646302	Thus, these results demonstrate that LAPTM5 promotes cell proliferation in vitro.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "these", "results", "demonstrate", "that", "LAPTM5", "promotes", "ce...
PMC11064533	Clump formation on the cell surface and the effects on the antimicrobial resistance were also studied.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Clump", "formation", "on", "the", "cell", "surface", ...
PMC11740207	Controlling their size is a crucial factor in optimizing differentiation protocols for specific lineages (Bauwens et al., 2008; Demirci et al., 2020).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11583010	Following various conjugations processes, the absence of the residual unconjugated drug-linker was checked by LC/MS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Following", "various", "conjugations", "processes", ",", ...
PMC10813895	RPFNA, a minimally invasive procedure, is well-suited for assessing short-term breast cancer risk in asymptomatic women.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RPFNA", ",", "a", "minimally", "invasi...
PMC11473843	Immunoblot analysis of the indicated targets in A549 cells treated with the indicated doses of Seliciclib or XMD8-92 or in combination for 24 h. (F) Immunoblot analysis of the indicated targets in A549 cells treated with 10 µM XMD8-92 or 10 µM Seliciclib or in combination for 24 h. (G) Immunoblot analysis for the indicated targets in A549 cells transduced with shRNA control (pLKO.1 hygro + Tet-pLKO-puro) or a shRNA against CDK5 (Tet-pLKO-puro-shCDK5 + pLKO.1 hygro), or a shRNA against ERK5 (pLKO.1 hygro-shERK5 + Tet-pLKO-puro) or in combination (Tet-pLKO-puro-shCDK5 + pLKO.1 hygro-shERK5).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5308810	We also performed Boyden chamber assay to confirm the enhanced migration of CXCR4, and showed that three times more cells migrated through the chamber.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC2196094	This shows that the RMCP-8 subfamily of proteases is expressed only at a very low level in these two CTMC populations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "shows", "...
PMC11448304	A total of 30,089 Khib modification sites were obtained by LC–MS, and 4635 modified proteins were detected (Fig. 4a).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC6835428	However, it is also possible to use cells freshly isolated from OC patients, thus resulting in models more adherent to reality.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However...
PMC11435360	According to these criteria, the N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) murine model of BC constitutes a suitable pre-clinical system with which to explore experimental interventions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11244823	Consequently, the full length gD1 molecule will be recognized by cross-reacting antibodies against gD1, which arise following exposure to either EHV-1 or EHV-4, as well as by type-specific antibodies, which emerge solely upon exposure to EHV-1 but not upon sole exposure to EHV-4.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8270637

PD-1, NFATc1, lamin B, and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) antibodies and anti-mouse/rabbit secondary antibodies for Western blot were purchased from Proteintech Group.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC11732523

Given the patient's limited response to two prior antiviral treatment for COVID-19, a third round was not pursued.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Given", "the", "patient", ...

PMC11792766

The cells underwent hypotonic treatment as outlined by Heger et al. (2018), were fixed on glass slides, and stained with GelRed nucleic acid stain.

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PMC5673955

Cytotoxic activity of RrA was tested in 72 h of incubation with Jurkat cells or normal CD4 T lymphocytes.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cytotoxic", "activity", "of", ...

PMC8984067

Test conditions were as follows: scanning range: 200 nm–1100 nm; slit width: 2.0 nm, and sampling interval: 0.5 nm.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC3035438

The selected samples of culture supernatants were first serially diluted in fresh culture medium and titrated by anti-apoferritin ELISA as above to determine the dilution required to obtain a maximal signal of O.D. = 0.7.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11680049

Before being introduced into in vitro culture, the primary explants underwent a stepwise sterilization process.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Before", "being", "introduced", "into", "in", "vitro",...

PMC11659921

The CNV information of angiogenesis and stemness‐related genes in OV. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "CNV", "information", "of", "angiogenesis", "and", "stemness‐related", "genes", "in",...

PMC11768281

Additionally, the IL-27R receptor has been identified as a critical regulator of IL-10 production, further modulating T-cell responses during malaria infection .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additio...

PMC11653533

Moreover, the bark utilized as an astringent, love potion, antibacterial against Staphylococcus aureus and Escherichia coli, and to treat gonorrhea, loose bowels, dysentery, hemorrhoids, gastrohelcosis, inflammation, burns, scabies, hiccup and heaving; leaves utilized in asthma, cough, sexual disorders, the runs, haematuria, toothache, migraine, eye troubles, gastric issues, scabies, tuberculosis, fever, loss of motion and hemorrhoids; fruits utilized in problems related to asthma, purgative, digestive, tuberculosis, fever, paralysis and hemorrhoids; latex used in neuralgia, inflammations and hemorrhages (Makhija et al., 2010).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11707832

Recurrent infections represent a predominant clinical feature observed in α-mannosidosis cases, as documented in prior literature .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Recurrent", "infections", "represent", "a", "pred...

PMC11301095

Continuous video EEG monitoring failed to detect brain waves.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Continuous", "video", "EEG", "monitoring", "failed", "to", "detect", "brain", "waves", "." ] } ]

PMC11775197

Previous reports have shown that the PPARγ agonist troglitazone inhibits colon cancer metastasis by inhibiting matrix metalloproteinase-7 (MMP-7) synthesis and the adhesion of extracellular matrix (ECM) proteins .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11252553

Due to its potential to mitigate radiation-induced lymphopenia with lower toxicity, Taurine is considered a valuable candidate for pre-treatment in radiation therapy.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Due", ...

PMC2196094

RMCP-2 and the three closely related proteases of the RMCP-8 subfamily were identified as the major mucosal MC proteases in rat.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RMCP-2", "and", "...

PMC8481254

We found that STZ induced CDK19 expression in transplanted tumor tissue, while CA reduced the increase in CDK19 expression induced by STZ (Fig. 3E).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9776316

No.: 2197), ATM (Cat.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No.", ":", "2197", ")", ",", "ATM", "(", "Cat", "." ] } ]

PMC8996378

The first-generation reversal inhibitors include calcium channel blockers, immunosuppressants, protein kinase C inhibitors and so on.

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PMC11473843

Cells were then washed with staining buffer and resuspended in 200 μL Propidium Iodide (PI) at a final concentration of 4 μg/mL (A427), 20 μg/mL (A549) or 40 μg/mL (HBEC3).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", ...

PMC10523483

Human fetal lung fibroblast cell line MRC5 was cultured in MEM medium (Cytiva).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Human", "fetal", "lung", "fibroblast", "cell", "line", ...

PMC9429973

Peri-CAR-T checkpoint blockade may ameliorate tumor-intrinsic resistance mechanisms.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Peri-CAR-T", "checkpoint", "blockade", "may", "ameliorate", "tumor-intrinsic", "resistance", "mechanisms", "." ] } ]

PMC10589262

The fate of membranous MT-KIT was tracked in a time-dependent manner to understand its role in GIST tumorigenesis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "fate", "of", "membranous", "MT-...

PMC10588957

AMPK promotes autophagy via phosphorylation (25).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "AMPK", "promotes", "autophagy", "via", "phosphorylation", "(", "25", ")", "." ] } ]

PMC9429973

Aims: To evaluate the associations of TCR repertoire and its diversity with asparaginase hypersensitivity in children with ALL.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "To", "evaluate", ...

PMC11682224

CHD1L promotes the expression of PD-L1 in cutaneous squamous cell carcinoma cells and promotes M2 polarization in TAMs. (

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PMC11604830

A further in vivo experiment was conducted involving the intravenous injection of PFCE‐NE in a model of acute neuroinflammation (see Data S1).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC5173112

Intriguingly, we found that there was significant difference in mRNA expressions of IL-8 gene between control and USP21 siRNA RCC cells lines (Figure 6A).

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PMC11772585

A, B Metabolic phenotypes of HSC-1 and A431 cells were determined by the both OCR and ECAR assays (n = 5).

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PMC11632064

Oxygen consumption rate in Rho-0 cells and parental controls (MeWo).

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PMC11643361

The development of effective cancer therapeutics remains one of the most significant challenges in modern medicine, with researchers continuously seeking novel approaches to target cancer cells while minimizing damage to healthy tissues.

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PMC11082662

Furthermore, the evidence suggests that elevated SMPDL3B contributes to the proliferation, migration, and invasion of ovarian carcinoma cells.

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PMC11400680

In this study, we use an open-source dataset called Expert Visual Cell Annotation (EVICAN) (4) for the experiments.

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PMC11098378

Understanding bacterial effector function is important because these proteins can be critical drivers of bacterial pathogenesis .

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PMC9473868

In summary, BAI inhibited FLS proliferation and EMT, whereas induced cell apoptosis through blocking the PI3K/Akt/mTOR pathway, supporting clinical application for RA progression.

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PMC4360730

Details and references for the requested additions are also submitted to ontology specific issue trackers.

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PMC9429973

All patients had parenchymal disease and all received bridging therapy.

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PMC11791203

The values are expressed as mean ± SEM (n = 6).

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PMC8728081

Furthermore, we have assessed the toxicity of Kajjali and Rasasindura in NIH3T3 cell lines and zebrafish larvae.

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PMC10747139

However, no cytotoxicity study was reported on healthy cell lines, and IC50 values were reported for standard drugs for comparison.

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PMC9429973

The accuracy of nomograms was verified by high concordance index and good agreement with the predicted value in calibration plots.

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PMC11682172

The numbers of identified proteins for each cell line are shown in Table 1.

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PMC9509578

The results show increasing interest in the nanomedicine approach to overcome MDR in cancer.

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PMC11724582

The following antibody dilutions were used: anti-GAPDH (1:10000, ABclonal), anti-αSMA (1:4000, Proteintech), anti-FAP (1:1000, ABclonal), HRP-conjugated secondary antibody (1:10000, ABclonal), anti-YAP/TAZ (1:1000, CST), and anti-GAPDH (1:50000, ABclonal).

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PMC9429973

With a median follow-up of 9.5 months (range 0.3-78.3), 3-years OS was 64% for patients with concurrent RS, 53% for untreated RS patients and 5% for treated RS patients (Figure; p<0.01).

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PMC11487720

We established stable transfectants of L929S cells expressing EGFP-TRAF2(124–233), ECFP-TRAF2, ECFP, or EGFP (Fig. 6B).

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PMC11787355

and Xylazin, 10 mg/kg i.p.)

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PMC11488203

Interaction of MSC with cancer cells either by direct cell-to-cell communication or by indirect processes including the release of EVs/exosomes has been studied previously .

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PMC9429973

Aims: Better understanding of relapse biology could improve treatment efficacy.

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PMC9429973

C. Wang, J. Liu, H. Lei, Y. Li, J. Wu, B. Guo, R. Hu, T. Liu, J. Wu, Y. Ding, C. Hu, S. Liang, C. Xiao, X. Liang, D. Huang, T. Yang, W. Zhang, Z. Yang, J. Li, Y. Nan, Q. Li, Y. Xiang, Y. Wu, Y. Liu Hematology; Chongqing University cancer hospital, Chongqing, China Background: HIV-associated lymphoma is the most common subtype of HIV-associated cancers, with a very low incidence.

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PMC11470381

Add 0.1 µg/mL of recombinant SDF1α (diluted in imaging medium, see Recipe 8) to the dish 10–15 min prior to acquisition during incubation.

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PMC11420784

C, Colocalization of LC3 and galectin-3 with UPEC in 5637 cells at 4 hpi.

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PMC11766332

MicroRNAs (miRNAs) play a role in ASD and may influence metabolic pathways.

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PMC11612315

To determine the subtype selectivity of exendin 9–39, we tested its effect on TRPA1.

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PMC10530622

These effects were blunted by treatment with or overexpression of bone morphogenic protein-7, which is an anti-fibrotic cytokine in the kidney .

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PMC11321678

Charles et al. analyzed the enhancers and super‐enhancers that are differentially regulated in MB subgroups and found that they recapitulate and extend the transcriptional and phenotypic features of these subgroups.

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PMC11676670

Plasmid pTagRFP-C-SRSF2 was kindly gifted by Dr. Marat S. Pavlyukov.

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PMC11201245

The BAC clones RP11-17M8, RP11-347C14, RP11-449D3, RP11-911D14, and RP11-122H7 are homologous to 8q24.33 and are labeled with Green-dUTP (Enzo Life Science, NY, USA).

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PMC11758416

Add 120 μL of 1X Trypsin-EDTA to wells of culture plate and mix thoroughly.f.

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PMC11629192

We assessed the therapeutic potential of OFA in five pediatric anti-NMDAR encephalitis patients who showed poor responses to the first-line immunotherapy.

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PMC8358176

After 24 h and the replacement of culture medium with a new one, MTT working solution (10 μL; 5 mg/mL in PBS) was transferred to each well.

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PMC11409031

In breast cancer, a model based on CD8 T cells is significantly associated with clinical outcomes and the sensitivity to treatment .

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PMC11638288

In summary, NKp46 ILCs play a pathogenic role in neuroinflammation, and they represent potential targets for treating inflammatory disorders of the central nervous system .

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PMC10858941

Accumulation of p62 is reduced in hypoxia compared to normoxia, which is consistent with its increased degradation in hypoxia .

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PMC11747949

Therefore, to improve osteosarcoma treatment outcomes, a better understanding of osteosarcoma biology is needed with a focus on macrophage/monocyte biology and hypoxia.

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PMC11394730

Targeting glucose metabolism as a therapeutic method in cancer treatment has a biological basis in the differences in energy metabolism between normal and cancerous cells .

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PMC7433824

We identified 8 and 31 unique proteins in U87 cell lines treated with 100 and 300 µM P4, respectively (Table 2).

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PMC9429973

All patients had the diagnosis of absolute erythrocytosis with moderate hyperleukocytosis and thrombocytosis.

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PMC11536589

It has been documented that the existence of a positive feedback loop between the long non-coding RNA (lncRNA) PVT1 and the Wnt/β-catenin signaling pathway, which played a role in the development of gemcitabine resistance in human pancreatic cancer (Zhou et al. 2020).

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PMC11360263

These clinical HCMV strains displayed oncogenic and stemness features when cultivated on HMECs and OECs.

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PMC6450504

At a fixed concentration of siRNA not fully complexed, the size of the nanosystem increased, and the ZP decreased due to the presence of excess/free nucleic acid and incomplete condensation of the bPEI-chains.

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PMC9024365

All constructs contain an in-frame HA tag at the N-terminus for detection.

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PMC9509578

QDs generate intracellular ROS, thereby causing cancer cell death through oxidative DNA damage .

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PMC11188874

E, Effect of WT and mutant HDAC6 on co-immunoprecipitation of HR23B.

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PMC11549062

Endosome and lysosome trajectories of cos7 cells with the treatments of PDGFR‐β inhibitor and overexpression, and PTP1B inhibitor or RNA knockdown. (

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PMC10605143

We postulate that HSF1 may be involved in the remodeling of the mammary gland architecture over the female lifetime, as well as the acquisition of invasive cancer cell phenotype.

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PMC11590005

The ideol-ogy of meritocracy which has become established in Brazilian society intersects with racism to maintain hierarchical racial positions .

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PMC9966931

Figure 1 depicts some of the bioactivities exhibited by each compound described above and the modes of action by which they are exerted .

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PMC7342409

For the imatinib group, imatinib mesylate capsule powder was dissolved in a 15 mg/mL working solution with normal saline.

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PMC11670407

Our results demonstrated that OTULIN expression was significantly upregulated in OS tissues and cell lines following cisplatin treatment but not in response to doxorubicin or methotrexate.

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PMC9429973

Cohort B enrolled pts who had early relapse after initial therapy.

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PMC11116779

The maximum effect was recorded after treatment with 500 μg/mL PS-NPs for 48 and 96 h, when A549 viability was reduced by 21 and 22%, respectively (Figure 1).

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PMC9024365

Neurons were blocked with 10% BSA for 30 min.

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PMC11740399

Various ratios of 3025@ML from 1:1 to 1:20 (w/w) (SRT3025:ML) were synthesized to determine the drug loading capacity.

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PMC11347429

Thus, it may have a function in the host’s defense against infections (GeneCards).

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PMC8143558

Other phytochemicals such as alkaloids, or interactions between phytochemicals, may be responsible for some observed and reported antimicrobial activity in plants.

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PMC7602170

Activated mTORC1 also activates Hypoxia-inducible factor 1-α (HIF1-α) .

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PMC4360730

As assays are not added to the ENCODE project regularly, we anticipate only 1–2 new term request for an assay per year.

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PMC7812570

C Inhibition of cell-cell HIV-1 transmission by GPI-anchored antibodies.

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PMC9646302

Thus, these results demonstrate that LAPTM5 promotes cell proliferation in vitro.

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PMC11064533

Clump formation on the cell surface and the effects on the antimicrobial resistance were also studied.

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PMC11740207

Controlling their size is a crucial factor in optimizing differentiation protocols for specific lineages (Bauwens et al., 2008; Demirci et al., 2020).

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PMC11583010

Following various conjugations processes, the absence of the residual unconjugated drug-linker was checked by LC/MS.

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PMC10813895

RPFNA, a minimally invasive procedure, is well-suited for assessing short-term breast cancer risk in asymptomatic women.

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PMC11473843

Immunoblot analysis of the indicated targets in A549 cells treated with the indicated doses of Seliciclib or XMD8-92 or in combination for 24 h. (F) Immunoblot analysis of the indicated targets in A549 cells treated with 10 µM XMD8-92 or 10 µM Seliciclib or in combination for 24 h. (G) Immunoblot analysis for the indicated targets in A549 cells transduced with shRNA control (pLKO.1 hygro + Tet-pLKO-puro) or a shRNA against CDK5 (Tet-pLKO-puro-shCDK5 + pLKO.1 hygro), or a shRNA against ERK5 (pLKO.1 hygro-shERK5 + Tet-pLKO-puro) or in combination (Tet-pLKO-puro-shCDK5 + pLKO.1 hygro-shERK5).

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PMC5308810

We also performed Boyden chamber assay to confirm the enhanced migration of CXCR4, and showed that three times more cells migrated through the chamber.

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PMC2196094

This shows that the RMCP-8 subfamily of proteases is expressed only at a very low level in these two CTMC populations.

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PMC11448304

A total of 30,089 Khib modification sites were obtained by LC–MS, and 4635 modified proteins were detected (Fig. 4a).

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PMC6835428

However, it is also possible to use cells freshly isolated from OC patients, thus resulting in models more adherent to reality.

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PMC11435360

According to these criteria, the N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) murine model of BC constitutes a suitable pre-clinical system with which to explore experimental interventions.

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PMC11244823

Consequently, the full length gD1 molecule will be recognized by cross-reacting antibodies against gD1, which arise following exposure to either EHV-1 or EHV-4, as well as by type-specific antibodies, which emerge solely upon exposure to EHV-1 but not upon sole exposure to EHV-4.

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