Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
 Community
1
PMCID
string
Sentences
string
ner
list
PMC11343332
Cancer is characterized by dysregulation of apoptosis, and methods to cause apoptosis in cancer cells have been investigated as potential cancer treatments .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cancer"...
PMC11297139
The shaded regions highlight the linkages between the TFAP2B gene and the EWS/FLI1-bound upregulated cREs via the proximal colocalization or the altered long-range chromatin contacts.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973
An exception to this finding are cells with FLT3-ITD mutations, which were also sensitive to RAS inhibition.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", "exception", "to", "this", "findi...
PMC11770199
Fluorescence images showed Dox initiating p14 protein expression and subsequently inducing cell fusion. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fluorescence", "images", "showed", "Dox", "initiating", "p14", "protei...
PMC9910796
Transmembrane protein pEP84R guides the assembly of the viral core beneath the inner envelope by interacting with polyprotein pp220, a binding that probably involves the N-terminal regions of both polypeptides.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
They both had short stature and mild splenomegaly but no dysmorphism.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "They", "both", "had", "short", "stature", "and", "mild", "splenomegaly", "but", "no",...
PMC11525293
Thalidomide treatment results in p63-dependent ACE2 downregulation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thalidomide", "treatment", "results", "in", "p63-dependent", "ACE2", "downregulation", "." ] } ]
PMC9964654
At the end of the treatment, the MTT assay was used, following a procedure similar to one previously described .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "the", "end"...
PMC8903741
In the presence of 600 μg/mL G-418, cells were selected and expanded.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "presence", "of", "600", "μg/mL", "G-418", ",", "cells", ...
PMC8708099
Absorbance was read at 590 nm.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Absorbance", "was", "read", "at", "590", "nm", "." ] } ]
PMC11661024
One is the possibility of expanding the investigation to a broader range of Lactobacillus strains and other species of probiotics.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "is", "the", "po...
PMC10125624
There were no differences in flap-related adverse events between tamoxifen and non-tamoxifen cohorts (OR: 1.00; 95%CI: 0.79-1.31; p=0.38).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11739504
Upon treatment with SAG, Smo was recruited to the whole axoneme with strong fluorescence intensity in control NIH/3T3 cells, whereas the fluorescence intensity of the Smo protein was significantly decreased in Kat2b depleted cells (Fig. 4a).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", ...
PMC11726848
For the analysis, doses close to LD50 and D37 were chosen for each of the irradiation regimes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "the", "analysis", ",", "doses",...
PMC11683130
The inhibitory serpins plays an important role both intracellular and extracellular, including coagulation regulation (110), inflammatory response, complement activation (102) and immune regulation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
A total of 240 putative protein interactors with a significance analysis of interactome were identified.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "total", "of", "240", "putative", "protein", "interacto...
PMC11736898
Although the effects of vitamin D supplementation on VDR expression in keloids have not yet been investigated, a clinical study of patients with atopic dermatitis suggests this is feasible .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7553912
Renal crystal deposits in WT and OSMRβ mice.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Renal", "crystal", "deposits", "in", "WT", "and", "OSMRβ", "mice", "." ] } ]
PMC11531735
Figure 3C demonstrates that mice treated with ER121 exhibited a substantial reduction in tumor volumes compared to the control group.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Figure", "3C", "demonstrates...
PMC11794568
Further detection of total and cleaved PARP and caspase3 proteins during apoptosis revealed that overexpression of CRIP1 did not affect the apoptotic process of melanoma cells (Fig. 3G).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11306331
To test this hypothesis, we compared the changes in the expression of FUS-CHOP-responsive genes to randomly chosen gene sets drawn from the same distribution of expression levels in our dataset, as well as to the overall changes across all genes (Fig. S6E–G).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9027909
The comparison of the expression of mir-874 between the B3STA and LPS was statistically significant (P-value = 0.0018) (Fig. 1E).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11536589
Yellow and purple represent high and low expression, respectively. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Yellow", "and", "purple", "represent", "high", "and", "low", "expression", ",", "resp...
PMC3995603
The drugs currently used to treat AD are limited by the significant adverse effects associated with their long-term use.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "drugs", "currently", "used...
PMC5833712
The levels of ERα are closely associated with estrogen-dependent growth and to increased metastatic potential of OEC by promoting epithelial–mesenchymal transition (EMT) through upregulation of Snail and Slug and downregulation of E-cadherin.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11363012
Since natural products are compartmentalized to specific cells, the biosynthetic pathways of plants can, in principle, be more rapidly elucidated using newly developed single-cell omics approaches.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10898159
Highly positive correlations between H19 and ETV1 were found in GIST cells, maybe via MEK and ERK pathways, as detected in colorectal cancer , and the mechanism underlining the regulation of FENDRR on the expression of KIT is not yet fully explored (Table 2).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10919056
In the TCGA database, least absolute shrinkage and selection Operator (LASSO) and Cox regression models were used to identify GJPs with independent prognostic effects as GRPS in ccRCC patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11585565
Jalili syndrome, an autosomal recessive disorder causing cone-rod dystrophy and amelogenesis imperfecta, is a rare genetic disorder impacting visual and dental development.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11686380
Analyses were done as in (A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Analyses", "were", "done", "as", "in", "(", "A", ")", "." ] } ]
PMC10999934
Furthermore, this study lacks experimental validation of the functional role of FBXO2 in chemoresistance, necessitating further research to uncover it.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ...
PMC10667689
Therefore, TIM-3 is recognized as a promising target for immunotherapy and monoclonal anti-TIM-3 antibodies are currently under evaluation in several clinical trials for AML and high-risk MDS (myelodysplastic syndrome) in combination with cytotoxic therapies (NCT04266301, NCT04150029, NCT04823624, NCT03946670, NCT04878432, NCT03940352, and NCT03066648).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11711127
However, much like the current state of tolDC research, diverse suppressive mechanisms and lack of consistent surface markers have hampered further characterisation of Tregs beyond the initial classical markers defined in the early 2000s.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11696576
After an overnight hybridization, the enzymatic conversion of substrate was read at OD420 nm using a Cytation 5 multimode platereader (Biotek Instruments, Winooski, VT, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6461034
Bar colors indicate targets of tyrosine kinase inhibitors BMS‐754807 (red), afatinib (blue), and imatinib (green).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Bar", ...
PMC10818573
RPA can be performed on small sample volumes and can be applied to a variety of sample types, including microorganisms, body fluids, surgical biopsies, organ tissues, and plant and animal products .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11463018
C NMR (126 MHz, DMSO-d6) δ: 165.70, 164.20, 151.32, 144.00, 136.91, 134.32, 132.94, 131.13, 130.22, 129.47, 129.20, 128.56, 127.53, 127.15, 126.79, 112.11, 112.05, 45.68.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10748106
The leverage matrix H is defined as Equation (15).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "leverage", "matrix", "H", "is", "defined", "as", "Equation", "(", "15", ...
PMC11575040
p < 0.05; **p < 0.01; ***p < 0.001 Interaction between miR-1270 and LINC00094 in melanoma cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC7802142
a Clustering and Heatmap analysis of 32 differentially packaged miRNAs in 293-NV and ReN-NV (TPMaverage > 1000, fold change > 1.5 and P < 0.05).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6379402
or their knockdown in cancer cell lines induces statistically significant change in cell viability (MWU p values ≤ 5% in column Cell viability change) Validation of the iCell rewired genes For each of breast, prostate, lung, and colorectal cancer, the table ranks the always-expressed genes according to their rewiring between cancer and control iCells (most rewired first).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11802929
When analyzing only the cell-capturing SCTs, the hydrophobicity of PG1 becomes even more prominent while PG2-3 distinctions diminish (Fig. 3d right).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973
Secondary objectives include PK, antileukemic activity and exploratory PD characterization.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Secondary", "objectives", "include", "PK", ",", "antileukemic", "activity", "and", "explora...
PMC11513011
Third, the data of DIB treatment and FoxM1 signaling pathway are missing.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Third", ",", "the", "data", "of", "DIB", "treatment", "and", "FoxM1",...
PMC9275501
Astragalus polysaccharides (APS) could exert anti-tumor effects by restoring immune organs, regulating cellular immune response and increasing the levels of cytokines IL-2, TNF-α and IFN-γ.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7802142
In this study, ReN-NV were prepared by extruding ReN cells through serial porous membranes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this", "study", ",", "ReN-NV", "were", "prepared", ...
PMC6684588
Figure 4Local administration of ACE-083 in a Trembler mouse model of CMT causes focal hypertrophy of skeletal muscle, increases muscle force generation and improves ankle dorsiflexion torque.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11502327
Multi-drug co-delivery is an effective means to reduce the occurrence of drug resistance in tumors, but it requires higher requirements for the complex structure of the vector.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11544122
when treated with Cmpd101 (a).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "when", "treated", "with", "Cmpd101", "(", "a", ")", "." ] } ]
PMC11551844
Therefore, only precipitates from JDH (8), termed JC-2, were selected for biological evaluation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "only", "precipitates", "from", ...
PMC11803918
Compared with deep-seated cancer types, red-light irradiation may easily penetrate skin tissues to reach melanoma lesions with minimal side effects.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Compared", "with", ...
PMC11787355
D170, P. (2025) https://BioRender.com/z72g103 (b).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "D170", ",", "P.", "(", "2025", ")", "https://BioRender.com/z72g103", "(", "b", ")", "." ...
PMC9429973
RNA was extracted from these samples and the relative abundance of lncRNAs, including some of those deregulated in CD34+ cells or already described as involved in hematological malignancies and myeloid differentiation, was assessed using qRT-PCR.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11787381
All samples were stored at −20 °C until analysis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "samples", "were", "stored", "at", "−20", "°", "C", "until", "analysis", "." ] ...
PMC10079526
Depth: 100).
[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Depth", ":", "100", ")", "." ] } ]
PMC2614415
The kinase activity of Aurora-A and Aurora-B is suppressed in a dose-dependent manner consistent with the known Ki values of VE-465.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "kinase", "...
PMC11392912
The PCR product was run on 1.5% agarose gel, stained with EtBr and the image was taken by ChemiDoc MP (Bio-Rad, U.S.A.).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9848491
IC50 of Z.LLNle.
[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "IC50", "of", "Z.LLNle", "." ] } ]
PMC11632064
Importantly, transcripts associated with antigen presentation were also induced in MeWo cells treated with BI-D1870 (Fig S2A), reinforcing a RSK-specific role.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC11087766
Nuclear cross-sectional area was determined by tracing the border of the DAPI-stained nuclei in ImageJ at its widest point.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Nuclear", "cross-sectional", "area", ...
PMC11637284
The IMS side of TAC60 then interacts with a single p166 molecule, which extends across the IM, forming a matrix filament that connects to the kDNA.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11544771
Cells, seeded on coverslips in 6-well plates (2 × 10 cells per well), were grown overnight.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", ",", "seeded", ...
PMC9429973
Methods: A cross sectional study was conducted at National Institute of blood diseases and bone marrow transplantation, PECHS campus from August 2021 - January 2022.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11705067
Interestingly, only CDKN2A showed higher expression in ccRCC tissues than normal tissues (Fig. 2A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interestingly", ",", "only", "CDKN2A", "showed", ...
PMC11670954
FD-4 flux was employed to assess paracellular permeability.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "FD-4", "flux", "was", "employed", "to", "assess", "paracellular", "permeability", "." ] } ]
PMC11703992
Specific intercellular interactions between each cell cluster were identified with prior knowledge of the interactions between signaling ligands, receptors and their cofactors.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Specifi...
PMC11763533
We also analyzed the effect of temperature on the green/red light intensities for COS-1 cells transfected with pCMV-Amy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ "We", "also", "analyzed", "the", ...
PMC9429973
After informed consent, pts were treated with oral parsaclisib for 12 wk at a starting dose of 1.0 mg once daily (QD; cohort 1) or 2.5 mg QD (cohort 2).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11394386
Immunoprecipitating with antibodies against HIF1α was performed using 5 μg of antibody (Invitrogen, PA116601).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Immunoprecipitating", "with", "antibodies", "against", ...
PMC9822769
Therefore, the activity of caspases 3/7 was investigated after 24 h CT of A2780 cells with 10 μM concentrations of cisplatin or 1–3.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "token...
PMC11770199
This process led to cell death by activating apoptosis and pyroptosis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "process", "led", "to", "cell", "death", "by", "activating", "apoptosis", "and...
PMC10996034
no. E032420; EarthOx Life Sciences) coupled with DyLight 594-TFP ester for 2 h. After washing three times with PBS, the cells were stained with DAPI dye solution, and incubated for 10 min in the dark.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11271278
We found that most of these amplicons, either in the extrachromosomal or chromosomal forms, harbor additional DNA segments originating from other chromosomal regions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973
The downregulation of IGHA1/IGHA confirmed patients immunoparesis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "downregulation", "of", "IGHA1/IGHA", "confirmed", "patients", "immunoparesis", "." ] } ]
PMC7961460
The survival analyses were performed by using the Affymetrix ID probe 219844_at and patients were split into two groups according to the best cut-off values of the expression values.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11742047
Moreover, as shown in Fig. 1A,B, to investigate the activation of apoptotic or necrotic processes, we extrapolated the IC20 of CBD at 24 h (10.08 μM for HL-60 and 23.32 μM for K-562, respectively); so, we could use it to activate these pathways and, at the same time, to keep a reliable number of cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10852540
The effectiveness of exogenous antioxidants in protecting tissues from oxidative stress in vivo is variable and depends on the type of antioxidant, its biopharmaceutical properties, its concentration at the site of action, and the nature of oxidative stress19.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10213179
no. 4959-GL) was used as the pre-cleared protein in the counter-selection step.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "no.", "4959-GL", ")", "was", "used", "as", "the", "pre-cleared", "pro...
PMC10674574
Caco-2 cells used in the pharmaceutical industry should be appropriately identified and confirmed as original Caco-2 cells.
[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Caco-2", "cells", "used", "in", ...
PMC10291556
After 72 h incubation, 10 μL/well of freshly diluted MTT (2.5 mg mL in PBS; Calbiochem, Darmstadt, Germany) was added, and the cells were incubated for an additional 2–4 h. The medium was removed, and the insoluble formazan product was dissolved in 100 μL/well DMSO.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7136814
When in combination with Vincristine, increased cell death compared to Vincristine or TPA/GSK126 alone was demonstrated.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "When", "in", "combination", "with", "Vincristine"...
PMC11591052
This may be the basis for 20E’s well-known anabolic activity.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "may", "be", "the", "basis", "for", "20E", "’s", "well-known", "anabolic", ...
PMC11734514
In conclusion, the presence of ergosteroids in marine sponge C. aerizusa extract showed a significant reduction in malignancy, migration, and invasion abilities in human lung carcinoma cells A549.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6600253
However, due to the low bioavailability and fast metabolization of RSV, the clinical value of RSV is limited .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "due", ...
PMC9398137
A subset of DLBCL and the majority of Burkitt lymphoma cell lines are dependent on MCL1 for survival.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "subset", "of", ...
PMC10958426
Dot plot of normalized expression level and expression percentage of cell-type-specific genes in 9 cell types. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Dot", "plot", "of", "normalized", "expression", ...
PMC3734024
Recently the cytokine IL-21 was identified as a growth factor for IL-10-producing B cells using a similar culture system as we have used in this study .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11476106
Data regarding the cluster area of the two ES cell lines are summarized in Tables S2 and S3.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "regarding", "the", "cluster", ...
PMC11711127
It is now widely acknowledged that metabolic reprogramming is crucial following the initial signals of Ag recognition, co-stimulation, and cytokine signalling.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", ...
PMC11225860
After the second round of division the cell cycle becomes accelerated and erratic, due to endomitotic division.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "the", "second", "round", "of"...
PMC10671321
However, at odds with the results of Sigoillot et al. , MuSK and rapsyn mRNA levels were not different from control muscle cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9503669
Concanamycin A-mediated rescue of MHC-I to the surface of HIV-infected cells enhanced the CTL response.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Concanamycin", "A-mediated", "rescue", "of", "MHC-I", "to", ...
PMC8903741
For this reason, we further cultured the two colonies separately in a flask with 40 mL medium and then purified the antibody utilizing PA beads followed by size-exclusion chromatography (Additional file 1: Fig. S3, S4).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612794
The key residues of Dsn1 important for maintaining the auto-inhibited state are labeled.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "key", "residues", "of", "Dsn1", "important", "for", "maintaining", ...
PMC11653533
As before, most of these compounds also manifested anti-inflammatory and anti-cancer activity.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "before", ",", "most", "of", "these", "compounds", "also", "mani...
PMC9429973
Notably, AML-LTS who had undergone alloSCT did not have increased risks of CHF, CAD, hypertension or diabetes, compared to survivors treated with chemotherapy only.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11615101
Biopsy synovium was collected from RA patients (n = 15) in Dulbecco’s modified Eagle’s medium (DMEM) (HiMedia, India) supplemented with 10% fetal bovine serum (FBS)(Gibco, USA) and 1% antibiotic solution (HiMedia, India).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11656657
Graph generation and statistical analyses were performed using GraphPad Prism (RRID:SCR_002798) version 10.2.3 software.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Graph", "generation", "and", "statistical", ...
PMC11155445
Conformational equilibria are present in the solution phase, while only one stable conformation was observed in the crystal, due to gaining free energy of crystallization and compact packing.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612508
After 96 h, 800 mL of ultra-pure (UP) water was incorporated into the solution with continuous stirring, followed by filtration through a 0.45 µm nylon membrane.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...