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OTAR3088
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BioData-CellLine_annotated

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PMC11155445
MOF had low proton conductivity at low temperatures and independent of humidity, because of ineffective dissociation and transportation of adsorbed water molecules.
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PMC11670954
In contrast, after BA treatment, the expression of these proteins decreased and the change in their distribution was partially reversed .
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PMC11588008
The cells with PBS were washed, and the cells were centrifuged and collected, frozen and thawed twice rapidly, and centrifuged at 10,000 × g for 10 min.
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PMC9622879
According to this figure, the daily benefits of the homes that have PV systems and ESSs (Home 1 to Home 3) in the community with the proposed CEMS are worse than those in the community with the prosumer-centric CEMS; however, the daily benefits of the remaining homes in the community with the proposed CEMS are better than those in the community with the prosumer-centric CEMS.
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PMC10158546
Semi-quantitative analysis of western blot and qPCR data revealed increased TUBB3 abundance in all cell lines beginning at day 7 post differentiation (Figure 3c,d), consistent with differentiation into neurons and astrocytes.
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PMC5941560
We confirm documented mutations in Jurkat and propose links from detrimental gene variants to observed expression abnormalities in the cell line.
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PMC9429973
20 pts retained remission during follow-up.
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PMC9429973
On the other hands, dihydroorotic acid (DHO) was decreased and orotate was increased in AZA-R cells (Fig. D).
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PMC11535726
D. Hawksw.,
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PMC9960565
in darkness under a nitrogen atmosphere (Scheme 8).
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PMC10631132
In contrast to the PBMC-derived cell line, the fibroblast-derived iPSC line (Fig. 5H) exhibited mononuclear cells with a distinct stellar-like phenotype following OC differentiation.
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PMC9429973
Image: Figure 1: 3D synergy plots showing average synergy scores for decitabine in combination with tolinapant in the CTCL line HH.
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PMC11791432
Compared with previous literatures, we supplemented abundant functional experiments on the basis of bioinformatics analysis to verify the function of ANXA1 in vitro and in vivo.
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PMC9541067
d Quantitative analysis to (c).
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PMC11773391
In other words, TMZ inhibited cell growth in a time‐ and dose‐dependent manner.
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PMC11802855
U The expression levels of CXCL7 and Ki-67 in the subcutaneous xenograft tumors of the CXCL7-OE group and NC group (via immunohistochemical).
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PMC11422497
The Annexin V-FITC/PI assay demonstrated that circ_SMA4 overexpression significantly suppressed GISTs cell apoptosis, whereas circ_SMA4 knockdown significantly promoted GISTs cell apoptosis (P < 0.05; Fig. 1C).
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PMC9429973
These models were tested for their response to JAK1/2 inhibitor.
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PMC9621239
Therefore, variations in HBV QS reflect changes in the internal microenvironment of infected cells.
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PMC11411131
After 48 h, the cells were lysed in tris-buffered saline (TBS) containing 0.5% Triton X-100 (TBS-Tx) for expression analysis, followed by SDS-PAGE and western blot analysis.
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PMC10798140
This article covers the synthesis, as well as the biological activity against the HepG2 cancer cell line, of the new quinoline derivatives 3a–3e (Fig. 2).
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PMC11680049
Live cultures of Fusarium oxysporum L. fungi, which had been stored for a long time in a refrigerator at +4 °C, were initially propagated on a nutrient medium containing mineral salts according to the MS formulation, without plant hormones.
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PMC11297139
The colors indicate normalized read counts (left, red) and log2 (LLPS-positive/LLPS-negative) read counts (right, yellow, and cyan).
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PMC7090062
Yellow dots represent autophagosomes. *
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PMC8984067
The linear regression equation for the standard curve was A = 0.216c − 0.001, and the correlation coefficient was R = 0.9929.
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PMC11657744
Representative transmission electron microscopy (TEM) images of longitudinally sectioned primary cilium from NIH3T3 cells.
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PMC11285179
However, the suppression effect is more pronounced after knocking out CCL28 than the control group (LLC-NC), and CCL28 knockout with supplementing RA could further synergistically inhibit tumor growth (Fig. 5G).
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PMC11387401
Interestingly, we could confirm 16.1- and 4.1-fold enrichment of AFF2 and AFF3 in the Tat nRIPseq samples compared to the IgG and GFP control samples (Appendix Fig. S8).Figure 4Analysis of the HIV-1 protein-host RNA interactors.(A) Gene ontology (GO) enrichment analysis was performed with DAVID (Sherman et al, 2022) for the RNA interaction partners of every protein detected in the Jurkat cell line.
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PMC8143558
The role of water in fighting pathogens is based on its ability in reducing microbial bioburden on hands and surfaces so that they are not transmitted into the body through the mouth, eyes, ears, or nose.
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PMC9429973
Chromatin association of candidate RNAs was verified using Chromatin Isolation by RNA Purification (ChIRP) by means of biotinylated oligonucleotides for target capture.
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PMC11721064
This induction phase was conducted under one of three culture conditions: (1) KSFM condition, employing commercial keratinocyte serum-free medium (catalog number 17005042; Thermo Fisher Scientific) supplemented with recombinant human epidermal growth factor (rhEGF) (Thermo Fisher Scientific) and bovine pituitary extract (BPE) (Thermo Fisher Scientific); (2) LNCs-KS condition, utilizing KSFM supplemented with LNCs conditioned medium at a 1:1 ratio; (3) LNC-SH condition, employing supplemented hormonal epithelial medium(SHEM) supplemented with LNCs conditioned medium at a 1:1 ratio.
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PMC10170482
Protein samples were separated using SDS-PAGE and then transferred to PVDF membranes.
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PMC8751435
Results show that CME causes pyroptosis‐featured cell bubbling and cell lysis and inhibits cell proliferation in A549 cell.
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PMC10204952
This co-culture system was cultivated using DMEM containing 1% FBS for 3 d. Subsequently, the cell culture media were collected by centrifuging at 10000 g for 15 min, filter-sterilized (pore size: 0.2 μm), and stored at -80°C for further experimental analyses.
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PMC9429973
Finally, in vivo reduction of mitochondrial ROS by MitoQ administration rescues mitochondrial activity and th3 HSC quiescence.
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PMC11607321
Additionally, proteomics is riddled with missing values (Supplementary Fig. 5a), affecting more predominantly lowly abundant proteins.
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PMC11806182
Estradiol was observed to down-regulate extracellular exosome production while up-regulating developmental processes.
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PMC11098378
The absorbance of each plate was read at both 490 nm and 680 nm within 15 min of adding Stop Solution.
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PMC11705862
Quantification shown in (J). (
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PMC9429973
Image: Summary/Conclusion: MRD quantification based on the use of cfDNA by NGS offers promising results and, in the future, could be a good option for disease monitoring or early detection of relapse.
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PMC11703992
We assessed transcriptional similarities between different T subclusters by calculating the Jaccard similarity coefficient using the characteristic genes.
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PMC11658074
Our study revealed that AT-EVs were internalized faster than ADSC-EVs were.
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PMC2193049
The reaction was incubated at 25°C for 20 min, at which time the reaction was quenched with cold 100% ethanol.
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PMC11343332
We observed that pycnogenolegulation of anti-apoptotic genes was associated with the inhibition of breast cancer cell migration.
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PMC11518994
Long read sequencing proved that the two identified variants are in trans, as shown in the image.
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PMC9429973
Pt characteristics are presented (Table).
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PMC8998437
Here, we showed that both the CCR1 transcript and the CCR1 protein on the cell surface were well represented in latency III LCLs and BL cell lines with the CD10-negative phenotype and concomitant co-expression of EBNA2, LMP1, and LMP2A/B. This finding is consistent with published reports demonstrating that in vitro BL cell lines that during establishing switched to latency III, display a gene expression profile consistent with a B lymphoblastoid phenotype , similar to those reported for LCLs generated in vitro by EBV infection of B cells .
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PMC11047729
It has been used in treating bone marrow-connected diseases, such as anaplastic anemia .
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PMC9429973
Summary/Conclusion: Cytogenetic investigations had an important significance for diagnosis, prognosis and selection the optimal treatment strategy of AML.
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PMC9429973
Dynamic International Prognostic Scoring System – Plus (DIPSS Plus) was used as well but was further grouped into two (low and high risk groups) instead of four groups.
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PMC11261875
Such investigations can potentially unveil novel anti-GIST therapeutic strategies in the future.
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PMC11747467
Immunohistochemical results indicated that RC48 could upregulate STAT3 expression.
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PMC11082662
Correlation of SMPDL3B expression with survival in patients with ovarian cancer. (
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PMC11549612
As depicted in Figure 1A, BOLA1 (p=3.48x10-10), BOLA2 (p=1.04x10-8), and BOLA3 (p=2.96x10-7) genes exhibited a significant up-regulation in KIRC cell lines (n=12) compared to control cell lines (n=5, Figure 1B).
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PMC11240448
They also do not detect feedback loops.
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PMC11794568
Fig. 6CRIP1 inhibits mitochondrial biogenesis in cutaneous melanoma cells. (
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PMC11406030
Previous studies reported two compounds, C28 and C36, that exhibited anticancer activity against a variety of cancer cell lines, partly mediated by LMTK3.
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PMC9429973
The logistic regression model shows that the D-d levels at ICU admission are statistically significant on the likelihood to have TE (χ(2)=9.089, p=.011).
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PMC11674146
Meanwhile, VIM is an intermediate filament protein which plays crucial roles in EMT, as seen by the increased mesenchymal phenotypes (Ramos et al., 2020; Chen et al., 2024).
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PMC6803987
Cells death (%) = [1 − (Number of viable cells/Total number of cells)] × 100%(2) HBsAg and HBeAg expression levels in the supernatant were detected in terms of the ELISA kits’ protocol.
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PMC11750165
Proteins were separated by SDS-PAGE and detected by immunoblotting.
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PMC9429973
Further investigation into the prevalence, implications, and management of thromboembolism in COVID-19 patients on ECMO will lead to significantly improved outcomes for this specific patient population.
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PMC11770746
The hind paw was touched vertically on the plantar surface with the tip of the filament.
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PMC11001582
Graph, mean ± s.e.m.,
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PMC10376064
Student t-tests were performed to determine the significant differences between the two groups.
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PMC11543885
Plot ROC Curve: Plot TPR against FPR to generate a ROC curve.
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PMC11576293
Therefore, we repeated the H NMR experiment for one of these intermediates, which had previously been observed in the b-form.
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PMC11768927
These studies underscore VSV’s promise as a versatile and safe oncolytic agent capable of targeting a wide range of tumor types.
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PMC5035325
Regarding to NeuGcGM3 expression, all animals showed a positive tumor cells, in both models.
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PMC9429973
The estimated OS probability of Int-2/ High patients was 83.9% at 24 months (Fig. E).
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PMC11576293
Following 4 days of incubation on MCF-10 A cells with each examined compound at a concentration of 50 μM, the vitality of the cells was assessed using the MTT test (Mahmoud et al., 2022; Mekheimer et al., 2022).
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PMC11805741
The parameters used were an energy cutoff of -0.5, a minimum helix length of 3 residues, and a minimum strand length of 3 residues.
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PMC9429973
In 3 out of 10 patients with biochemical relapse, EM disease was not observed despite being present at the time of diagnosis.
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PMC9596868
This is mostly attributed to the induction of telomeric damage that occurs due to the inhibition of telomerase activity, which causes telomere uncapping followed by activation of DNA damage response and apoptosis or cell cycle arrest .
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PMC11790599
Then the pellets were infiltrated and embedded in epoxy resin (Electron Microscope Sciences).
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PMC9429973
Patients are currently being enrolled in the expansion cohort(400mg).
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PMC11194678
Scale bar, 10 μm. (
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PMC3203927
Although we reduced the number of probesets to be analyzed from the genechip total of 54000 to 681, by focusing only on cytokines, the number of variables (transcript expression level in our case) still greatly exceeded the number of samples.
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PMC11594641
Next, we analyzed the expression of tetraspanins (CD63, CD81) and ESCRT-proteins (Alix and TSG101) in cell lysates and sEVs by Western blot (Figure 5A).
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PMC11707577
Here we leveraged on the unique properties of bacteriophages (protein‐based structure, possibility to be genetically engineered, tropism for specific cell types) to biofabricate a novel hybrid nanostructured material, biocompatible, stable, highly photoactive and receptor‐specific.
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PMC9444294
Left: HSSYII synovial sarcoma cell line; right: SYO-1 synovial sarcoma cell line.
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PMC9596868
Significant upregulation of p21 expression occurred upon co-treatment as is observed in real time PCR analysis and western blotting (Figs. 5A and Supplementary 5B).Fig.
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PMC11055510
For example, CircITGB6 promotes cisplatin resistance in ovarian cancer by resetting tumor-associated macrophage polarization to the M2 phenotype; m6A RNA methylation regulator is an important player in ovarian cancer pathology.
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PMC11267830
Consequently, our research suggests that THOC1 may be considered a candidate factor for dependency splicing in future therapeutic applications .
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PMC11694625
Compared with benzo quinoline aromatic hydrazone derivative (compound 1, IC50 = 19.85 ± 4.15 μM) and quinoline hydrazone derivative (compound 18b, IC50 = 14.1 μM),3b and 3c showed better antiproliferative activity against MCF-7 cells.
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PMC11711935
Consequently, they are increasingly attracting attention.
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PMC11348300
injection, peaking at 4 h. Tumor tissue follows as the second most intense fluorescence source, reaching its maximum at 3 h (Fig. 4C).
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PMC2944824
MEF from p53 wild-type (wt) and knockout (ko) mice were transfected with Rk5Hr and apoptosis was induced in cultures with staurosporine (sts) and tunicamycin (tm).
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PMC11441402
It is also important to note that the whole population of cells is not able to be assessed with the PI-based flow cytometry method.
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PMC11670954
Compared with that in the BL + Y-27632 group, the TEER value in the LPS+ Y-27632 group was significantly lower(P < 0.0001).
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PMC9429973
FLAIR was adapted in July 2017 to add two arms, I monotherapy and I+V. I was given at 420mg/day.
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PMC11732628
no. GB11001; 1:2,000; Serivicebio, Wuhan, China) overnight at 4 ℃.
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PMC11265931
The apoptotic effect of garlic SEVs was examined using th Annexin V detection kit in accordance with the manufacture’s protocol.
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PMC11594588
Among the numerous therapies used in heart diseases, the most common is mechanical circulatory support (MCS), which is becoming a standard therapy for patients with advanced HF with a significant impairment of ventricular ejection fraction .
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PMC11574029
E, F Further validation of PI3K/AKT signaling pathway activity by treating T24 and 5637 cells overexpressing SPP1 with the PI3K-specific inhibitor LY294002, as assessed by Western blot.
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PMC9398137
We designed several single-guide RNA pairs for CRISPR/Cas9 inactivation of each gene of interest.
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PMC10604092
These cytokines also transmit leptin-like signals to the hypothalamus, resulting in loss of appetite and inducing body weight control responses that mimic the condition of sufficient body fat reserves .
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PMC11001582
Graph, mean ± s.e.m.,
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PMC9812014
The dosage required for alkaloids to inhibit these viruses compared to the positive control drugs was also lower than the standard drugs.
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PMC9429973
All patients reached neutrophil graft and 31 patients (88.6%) reach platelet graft with a median time of 19 (12-29) and 14 (10-36) days respectively.
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