Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
 Community
1
PMCID
string
Sentences
string
ner
list
PMC11656380
The blots were blocked with 5% skim milk in PBS-Tween 20 (0.1%) for 30 min and probed overnight at 4 °C with the following 1:1000 diluted primary antibodies: caspase-3 (CST #9662), cleaved caspase-3 (Asp175) (CST #9664), PARP-1 (CST #9542), HMGB1 (CST #3935) and 1:10,000 diluted anti-β-actin antibody (PM053–7; Medical & Biological Lab.,
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10998613
CRISPR IVT gRNAs were designed using GeneArt™ Precision gRNA Synthesis Kit and the DNA oligos were synthesized based on the gRNA designs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CRISPR"...
PMC11754784
Researcher contributions and authorship criteria have been carefully considered throughout the research process.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Researcher", "contributions", "and", "authorship", "criteria", "have", "been", ...
PMC11201245
As in Weimer et al. (1999), the BAC DNA is labeled with fluorescent dyes using a DOP-PCR .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "in", "Weimer", "...
PMC10761571
16.0 software and one-way ANOVA analysis were used to evaluate the statistical difference between the NPs treated and control cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "16.0", "software", "and", ...
PMC9429973
In PET-MF there was a significantly higher frequency of M-GVs in ASXL1 (47% vs 34%, p=0.01), SRSF2 (5% vs 1%, p=0.01), U2AF1 (9% vs 4%, p=0.04) and CBL (7% vs 2%, p=0.01) compared to PPV-MF.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3675084
A2780-1A9 cells were cultured in RPMI-1640 medium with 10% FBS, the 1A9-PTX10 cells were maintained in the same medium supplemented with 15 ng/mL paclitaxel and 5 µg/mL verapamil (a P-gp antagonist) , .
[ { "tags": [ "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11361748
Secondary antibodies (cf.
[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Secondary", "antibodies", "(", "cf", "." ] } ]
PMC9847912
CEMss cells were grown in Iscove’s modified Dulbecco’s medium (IMDM) with GlutaMAX™-I (Gibco, Life Technologies Corp., Grand Island, NY; catalog number 31980-030).
[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6771295
SIRT1 silencing resulted in the downregulation of beclin-1 protein levels in U2OS cells treated with resveratrol (Figure 5Ai, compare bars 4 and 8).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC11627133
N=50 cells) of HEK293T cells expressing H2B‐GFP, derived from confocal images as shown in E) giving the in cellula fluorescence turn‐on values.
[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11472639
Here we show that an individual bout of cycling 15% above anaerobic threshold induces a substantial increase in total CD3CD56CD38 NK-cells (+305%), with a preferential increase to CD3CD56CD38CD16 NK-cells (+352%).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11391695
In the pcDNA/PEI/NPs@M treatment group, tumor volume and weight were significantly reduced and rendered lighter in comparison to the negative vector group (Fig. 6C, D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11718031
A higher titer is generally achieved by increasing cell count or cell-specific productivity.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "higher", "titer", "is", "generally", "achieved", "by", "increasing", ...
PMC4443654
accuracy; AUROC, area under the receiver operating characteristic curve; PCC, Pearson correlation coefficient; RMSE, root mean-squared error.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "accurac...
PMC11082662
The cells were washed with ice-cold phosphate-buffered saline (PBS) thrice before being collected into a 1.5-mL Eppendorf tube.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cells", "were", ...
PMC10999934
The two HGSOC scRNA-seq datasets were obtained from the Gene Expression Omnibus (GEO) database.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "two", "HGSOC", "scRNA-seq", "datasets", "were",...
PMC9351137
D The effects found with Barasertib treatment are summarized in the graph.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "D", "The", "effects", "found", "with", "Barasertib", "treatment", "are", "summar...
PMC4659567
Interestingly, no intermolecular π-π stacking interactions were found in the crystal structure of 6.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interestingly", ",", "no", "intermolecular", "π-π", "stacking", ...
PMC11684269
First, it serves as an essential component of cellular membranes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "First", ",", "it", "serves", "as", "an", "essential", "component", "of", "cellular", ...
PMC11718031
This could be because Efficient B plus maintained a relatively hypoosmotic environment throughout the fed-batch process, which enhanced nutrient transport and improved culture longevity, as reported by Sue et al. (Sue Lee and Min 2001).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11786704
Then the protein was separated via 10 % or 12 % SDS-PAGE and transferred to 0.22 μm PVDF membrane.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", "the", "protein", "was", ...
PMC10452486
Cells grown at reduced temperature seem to upregulate HC dimers in HLA-B27 and HLA-A2 .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "grown", "at", "reduced", "temperature", "seem", "to", "...
PMC11552389
A 1% formaldehyde solution was used to cross-link A375 cells that had been transfected with Flag-tagged FOXN3 overexpression or empty control vectors (1 × 10 cell/sample) at 37 °C for 10 min, after which the Magna ChIP™ protein G Kit (Millipore Co., MA, USA) was used based on prepared directions to isolate nuclear lysates.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11665555
Initial assays were performed to optimize cell number, FCCP concentration, and oligomycin concentration (data not shown).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Initial", "assays", "were", ...
PMC8584666
For the colony formation assay, the method described previously was modified.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "the", "colony", "formation", "assay", ",", "the", "method", "described", ...
PMC10178190
Cell lines: Human OV-90, a high-grade serous ovarian cancer histology type, and platinum-sensitive and resistant OC cells A2780 and A2780CisR, respectively, were obtained from the American Type Culture Collection [ATCC] (Manassas, VA, USA).
[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O"...
PMC10669128
Treatment with PD-1 checkpoint inhibitor pemrolizumab significantly inhibited the tumor growth of PDX tumors in HuNGS mice, assessing the potential utility of the model for preclinical immunotherapy research .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11754094
If the deletion was more than 100 bp and the deletion spanned a region within 100 bp of the cleavage site, the deletion was classified as a large-deletion mutation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11763111
Tumor burden of mice was measured every 1 week.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tumor", "burden", "of", "mice", "was", "measured", "every", "1", "week", "." ] } ]
PMC10926885
Furthermore, we corroborated a subset of the findings from the bioinformatics analysis by experimental methods such as co‐immunoprecipitation, reverse transcription polymerase chain reaction (RT‐PCR) and other relevant techniques.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11348300
The statistical range and variability across these models provide the strongest evidence to date of the likely value in oncologic functional imaging.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "stati...
PMC11726848
Micrographs of the cells were obtained using a wide-field microscope Axio Vert A1 (Carl Zeiss, Germany).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Micrographs", "of", "the", "cells...
PMC10178190
Moreover, a reduction in pERK1/2 levels in samples exposed to CM derived from HS-5 or TA HS-5 (TA-HS-5) was correlated to decreased cPARP levels.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10218459
In the case of Ewing sarcoma, these are tumors that can only receive local treatment during surgical resection.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "case", "of", "...
PMC11224206
It is widely accepted that body temperature in women changes throughout the menstrual cycle .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "widely", "accepted", "that", "body", "temperature", ...
PMC10955424
Thus, drugs targeting VEGF signaling pathway expected to be beneficial for OC patient as previously reviewed .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "drugs", "targeting", "VEGF", "...
PMC10713411
Both aberrant or absent apoptotic signaling and excessive expression of apoptosis inhibitors can lead to the survival of tumor cells .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Both", "aberrant", "or", ...
PMC11363012
Since the size of the protoplasts obtained from the tissues used in this study varied between 16 and 45 μm, 50 μm wide wells were used.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11265931
100 μL of glucose-PBS was mixed with 10 μL of MTS reagent for one well and the total amount was calculated for each well.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11342785
From this, we defined a minimal fragment (TPPP 45–196) that retains cluster-dependent MT association for synthetic applications (Fig. 3C).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11629461
Quantitative analysis of calcium peak areas above baseline (per 10 min) from multiple experiments (N = 5–7).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Quantitative", "analysi...
PMC11499381
These products were diluted to between 20 and 30 ng/µL in UltraPure H2O.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "products", "were", "diluted", "to", "between", "20", "and", ...
PMC11321678
Statistical results of the percentage of medulloblastoma tumor size divide the whole section.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "results", "of", "the", "percentage", "of", "medulloblastoma", ...
PMC11224020
For the other mask’s movie, we applied the ‘distance map’ function, which generates a Euclidean distance map.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "the",...
PMC6642070
Increased lactate was also present in type II predominant glycolytic muscles rather than type I predominant oxidative muscles, associated with compromised maximum swim duration time.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11461833
The empty vector was transfected into WT HEK293 cells as a control. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "empty", "vector", "was", "transfected", "into", "WT", "HEK2...
PMC11507371
Increased ROS formation can trigger a compensatory redox adaptation response to keep ROS levels just below the apoptotic threshold.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Increased", "ROS", "formation", "...
PMC2196094
When the MC extracts were radiolabeled with H-DFP, major incorporation of radioactivity was observed for the ∼32- and ∼29-kD bands, indicating that these bands correspond to serine proteases (Fig. 1, lane B).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9118379
To be specific, all of the identified target and decoy variant PSMs were ranked in a decreasing order of their discrimination scores calculated by the search engine.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8358006
h Gene ontology and pathway enrichment significance (−log10 (P value) values) are not correlated for GO terms shared between 1172 GSDs marked genes and 388 random selected genes. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11335267
F and G) Confocal microscopy images, taken at low (upper panels) or high (lower panels) magnification, of coronal sections of brains from mice expressing Agrp-tdTomato (F) or Pomc-GFP (G) and labeled with an Alx3 antibody.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11727000
Of the 146 proteins retrieved from SH-SY5Y neuroblastoma cells, there were 13 tier-one cancer genes from this database (Table S2). .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11464982
A comparison of the NOAEL 1010 mg TOS/kg bw per day from the 90‐day study in rats with the derived exposure estimates of 0–0.003 mg TOS/kg bw per day at the mean and of 0–0.006 mg TOS/kg bw per day at the 95th percentile, results in a margin of exposure of at least 168,333.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11531735
These observations underscore the need for advanced TKIs to address the escalating challenge of brain metastases associated with HER2-positive metastatic breast cancer.6 The use of TKIs in treating HER2-positive breast cancer is not without potential toxicities.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11637284
, (F) and (G) as above but TAC60-RNAi cell lines complemented by TAC60ΔC283-myc and the indicated mini-p166-HA mutants were analyzed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973
Serious AEs were reported in 8 patients (31%).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Serious", "AEs", "were", "reported", "in", "8", "patients", "(", "31", "%", ")"...
PMC6889484
Western blot analysis shows the level of A3G-D128K-P2A expressed in the CEMSS/D128K cell pool (37%) compared to the level in the CEM/D128K cell pool (set to 100%) and normalized to α-tubulin.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11420784
The coverslips were mounted in antifade reagent with 4′,6-diamidino-2-phenylindole (DAPI) for 5 minutes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "coverslips", "were", "mounted", "in", "antifade", "r...
PMC5810978
The increased NoV RNA levels detected in this study (1.0–2.8 Log10 increases) were similar to those in the previous reports .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "incre...
PMC7022782
The future direction could be to specifically modify nanoparticle surface to improve uptake of the systems in tumoral cells, also by active intracellular transport.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11659921
For the purpose of our analysis, we focused on implementing the xCELL algorithm.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "the", "purpose", "of", "our", "analysis", ",", "we", ...
PMC11699465
We analyzed the interacting nuclear proteins of TMEM199 from the nuclear extractions by IP–MS assay, which suggested that the FOX proteins above can interact with TMEM199(Table S2).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11209164
A notable example is Talimogene laherparepvec (T-VEC), a Herpes Simplex Virus (HSV-1)-based oncolytic virus, which garnered FDA approval in 2015 for treating melanoma .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
The rate of pts in MR3 at 12 mos was 59% (already reported).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "rate", "of", "pts", "in", "MR3", "at", ...
PMC8540692
The model defines the permeability basing on the passive diffusion across the BBB and nasal mucosa.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "model", "defines", "the", "permeability", "basi...
PMC7351993
Microalgal cultures were grown in culture flasks (working volume: 20 mL) in a 14 h/10 h light/dark cycle with illumination at 120–140 μmol photons m s at 25 °C using AF-6 medium.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Median follow-up of RRWM cohort from second line therapy was 5.1 years (95% CI: 4.5-6.3).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Median", "follow-up", ...
PMC11409031
To further understand the functions of these hub genes, a functional enrichment analysis was carried out using Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG), facilitated by the 'clusterProfiler' package.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11720107
Similarly, in the SCC-15 cell line, the Ornak, Violeta, and Morado garlic extracts increased SOD1 protein expression by 82.4 pg/mL, 58.6 pg/mL, and 91.1 pg/mL, respectively, compared with the control (Figure 8F).
[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11473750
Patients were subgrouped above or below the upper decile of RNF121 mRNA expression (High; RNF121_hi, Low; RNF121_lw).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "...
PMC9429973
The pathologies responsible for acquired Willebrand syndrome are diverse; including lymphoproliferative and myeloproliferative syndromes,autoimmune and cardiovascular diseases, solid tumors, and even certain medications.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11190238
A hierarchical regulatory landscape between 46 (co)transcription factors and 13 miRNAs was identified to be critically required for EMT in the non-tumorigenic mouse mammary epithelial cells NMuMG.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellL...
PMC11665584
We did not observe spontaneous tumorigenesis in either healthy or wounded PITX1 skin in the limited time scale we conducted these studies, suggesting that PITX1 expression alone or in combination with wounding is not sufficient for immediate tumor initiation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11607321
All datasets were standardized by z-score, except copy number.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "datasets", "were", "standardized", "by", "z-score", ",", "except", "copy", "number", ...
PMC11747949
Protein array depicting different fold changes in protein expression of CCR2 treated versus vehicle control cells from coculture in hypoxia and normoxia.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Protein", "a...
PMC11721295
Ligands and receptors were considered significantly different if P was less than 0.05.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ligands", "and", "receptors", "were", "considered", "significantly", "different",...
PMC9429973
Aims: The aim of this study is to develop a lipid nanoparticle delivery system to encapsulate a therapeutic siRNA targeting the MLL/AF4 breakpoint and explore the impact of this in t(4;11) cell lines.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Children there is greater difficulty in maintaining adequate coagulation times, measured in times in therapeutic range (TTR) due to the significant individual variability in anticoagulant medication that can cause thrombotic or hemorrhagic complications.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10237474
After recovering from antibiotic selection, both HEK293S GnTI and Expi293F GnTI stable pools showed comparable viability and viable cell density (VCD) in small-scale 4-mL production cultures (Fig 3C).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11545737
Neisseria genus includes two important pathogens: Neisseria gonorrhoeae (the gonococcus) and Neisseria meningitidis (the meningococcus).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Neisseria", "genus", "includ...
PMC11509224
Both compounds proved to be inactive in the tested cancer cell lines.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Both", "compounds", "proved", "to", "be", "inactive", "in", "the", "tested", ...
PMC8345486
The compounds affected cancer cell viability in the following order of potency: C2′ derivatives (22, 23, 24) > C8 derivatives (18, 19, 20) >> parent metalla bis(dicarbollides) 1, 2 >> parent 3; and N derivatives summarized separately: 16 >15 >>14.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11725127
G, H) Ub-AMC assay comparing WT USP2 and the USP2 mutant, indicating a reduced inhibitory effect of GA on USP2. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC8097906
Derivatization and analyses of metabolites were carried out by a GC (7890 A, Agilent, Santa Clara, USA) coupled to a Quadrupol-Time-Of-Flight mass spectrometer (impact II, Bruker Daltonik, Bremen, Germany) via an atmospheric pressure chemical ionization ion source (APCI).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11753435
In addition, 10 top-scoring peptides predicted to bind to the SS18-SSX1 protein using PepPrCLIP were cloned in frame with CHIPΔTPR in an altered pcDNA3.1 expression vector that coexpresses IRES-TagBFP.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11321678
Visualization of marker genes of each subgroup.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Visualization", "of", "marker", "genes", "of", "each", "subgroup", "." ] } ]
PMC11736898
ANOVA Analysis of variance, CAMP Cathelicidin antimicrobial peptide, EDN1 Endothelin 1, FZD7 Frizzled 7, HAS2 Hyaluronan synthase 2, MMP1 Matrix metallopeptidase 1, MMP3 Matrix metallopeptidase 3, POSTN Periostin Expression of VDR in normal and keloid keratinocytes, in the presence or absence of vitamin D, was variably affected by the inhibitors.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11525028
Clinically, there is a consensus that a drug dose of 100 mg/kg daily in mice is equal to a dose of 8.13 mg/kg daily in humans.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11665584
Overall, PITX1 skin increases the quantity of actively signaling neutrophils that may be key actors in reshaping tissue morphology.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overall", ",", "PITX1", ...
PMC11637716
EFL1 residue His30 lies within the G1 motif, also known as P‐loop, that binds to the α‐ and β‐phosphates of GTP (Figure S2), while residue Asn867 maps to domain IV (Figure S2), which is important for functional interaction with the SBDS protein. ,
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11541241
We also expect that these chemical fungicides and biopesticides will be commercially available in the future.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "also", "expect", "that", "these", "chemical", ...
PMC11574271
The receptor tyrosine kinase (RTK) receptour d’Origine nantais (RON), also known as macrophage-stimulating protein (MSP) 1 receptor, belongs to the unique MET RTK family, which contributes significantly to epithelial tumorigenesis and chemoresistance .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11543853
Virions that cannot release their genomes are probably degraded by the cells that endocytosed them.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Virions", "that", "can", "not", "release", "their", ...
PMC11674441
mRNA expression was combined to identify potential neoantigen candidates.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "mRNA", "expression", "was", "combined", "to", "identify", "potential", "neoantigen", "candidates", "." ...
PMC11790599
Human breast cancer cell lines, human normal breast epithelial cells, human prostatic stromal myofibroblast cells, human colon epithelial cells, human umbilical vein endothelial cells, and human hepatocyte cells were used to determine the growth inhibition effect of TSL. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11781181
Specifically, NCOA4 selectively interacts with the FTH1 subunit of ferritin 12.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Specifically", ",", "NCOA4", "selectively", "interacts", "with", "the", "FTH1", ...
PMC9429973
In the 18 siltuximab-treated patients who achieved the primary endpoint of durable tumor (radiologic) and symptomatic response, most first achieved rapid normalization of various laboratory parameters and symptomology (median of 0.8 months to normalization based on a 34-point MCD symptom score) (Table 1).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11673902
In cell mechanics studies, the magnitude of this negative pressure can be used to characterize the deformability of the cell, i.e., how much the cell deforms when a force is applied.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Given the acceptable safety profile and efficacy of add-on parsaclisib, MF patients with both low and higher PC may be able to benefit from parsaclisib-ruxolitinib combination therapy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...