OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC6337547	The biosynthetic pathways of polyphenols include the shikimic acid and phenylpropanoid metabolism pathways .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "biosynthetic", "pathways", "of", "polyphenols", "include", "the", "s...
PMC6901583	The transfection of the pcDNA-3.1(+)-BRD4 vector led to increased BRD4 in the GIST-882 and GIST-T1 cell lines compared with the transfection of pcDNA-3.1(+) alone (Fig. 2a).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC9429973	Median overall survival (mOS) was 62.5 mo (95% CI, 51.7−NR; 5-y PFS and OS rates, 24% and 52%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11770130	The phospho-proteomics analysis on the eWATs from lean control and Ntsr2 AKO mice with comparable body weight identified significant changes in the phosphorylation of multiple proteins (Fig. 3a; Supplementary information, Table S1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8916024	In snails, the gut is the main site for nutrient absorption and utilization (Pawar et al., 2012; Dar, Pawar & Pandit, 2017).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11694625	The IC50 values were calculated according to the inhibition rate at a different concentration.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "IC50", "values", "were", "calculated", "according", "to", ...
PMC9429973	Median Ferritin was 322 ng/ml (range 17-1236) and median Alkaline Phosphatase was 81 U/L (range 29-355).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9878562	Under these conditions blood endothelial cells die and the remaining cells are composed of fibroblastic reticular cells (FRCs) (~40%) and LECs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11806818	Reprinted with permission from As a gynecological malignancy, cervical cancer occurs mostly in young patients .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Reprinted", "with", "permission", "from", "As", "a", ...
PMC11337594	B, C) A375 and GSDME-KO cells were treated with different doses (0, 1.0, 2.0 and 3.0 µg/ml) of TER for 24 h, followed by Annexin V-FITC/PI staining and flow cytometry analysis (n = 4).	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC9429973	Conditioning regimen was reduced intensity in 78.6% (n=11) and myeloablative in 24.6% (n=3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Conditioning", "regimen", "was", ...
PMC9429973	Although haemoglobin (Hb) levels have been found to be correlated to QoL, it is widely reported that other factors are important in determining QoL and need for transfusions can vary despite a stable Hb level.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9777812	With Western blot analysis, the same expression trends of CDKN1A gene were found at the protein level (Figure 3E,F).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	At a median follow up of 16.2 months (range 9-29 months), 9/10 patients are alive and in CR with no chronic GvHD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11634794	Additionally, LAMP1 was identified as a direct target responsible for UBL4A-induced tumor suppression and autophagy inhibition.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "LAMP1", "was", "identified",...
PMC9429973	The median CSF concentration of orelabrutinib was 28.7ng/ml (rang 11.8 ng/ml to 52.7 ng/ml).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "median", "CSF", "concentration", "of", "orelabr...
PMC11472639	indicates a significant difference from post-exercise at p < 0.01.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "indicates", "a", "significant", "difference", "from", "post-exercise", "at", "p", "<", "0.01", ...
PMC11348300	This consistency further substantiates the utility of PpIX fluorescence in capturing oxygen dynamics and highlights its potential as a valuable tool in elucidating intricate cellular oxygenation processes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11471157	Furthermore, immunostaining with αSMA indicated that only a small fraction of cells differentiated into myofibroblasts, with the majority of NIH/3T3 cells testing negative for αSMA (Fig. 3I).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", ...
PMC11621493	Statistically significant differences are shown as: ∗P < 0.05; ∗∗P < 0.01; and ∗∗∗P < 0.001.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistically", "significant", "differe...
PMC10745221	A protein with SDMA near 15 kDa was also detected in the 143B lysates in Fig 2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "protein", "with", "SDMA", "near", "15"...
PMC10589262	ATF6 activation was frequently observed in 67% of patients with GIST (n = 42), and was significantly associated with poorer relapse-free survival (P = 0.033).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11224206	This means that for a temperature shift of 10 °C, the metabolic rate will double or halve, and for a change of ~ 1 °C, i.e. the minimum order of magnitude being considered here, 10%.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9412887	41.6 °C.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "41.6", "°", "C", "." ] } ]
PMC8193046	For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)Fig.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", ...
PMC10222971	Therefore, a flow cytometric assay of Annexin V/PI was conducted to quantify the apoptotic profile in quinone-treated IGROV-1 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Therefore", ",", "a...
PMC9599726	The DAB-Ni solution was prepared by dissolving 0.06 g of nickel ammonium sulfate (Fluka, Buchs, Switzerland, Cat# 09885) and 2 mg of DAB (Sigma-Aldrich, St. Louis, MO, USA, Cat# D5637) in 10 mL of 0.05 M Tris/HCl, pH 8.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10178190	The HGF/MET axis was reported as a potential key contributor to promoting chemoresistance in cancer cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "HGF/MET", "axis", "was", "reported", "as", ...
PMC11435360	To evaluate tumor growth following intravesical therapy, the mice underwent a second scan on week 19.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "evaluate", "tumor", "growth", "following", ...
PMC11544122	Endocytosis was calculated as a fractional decrease in cell surface receptors in CXCL12-treated cells compared with vehicle-treated cells after background subtraction, which was assessed in parallel using an isotype control antibody.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8711270	Although only serotypes AAV1 and AAV8 were tested, this suggests that HEK293-produced rAAVs are preferred due to the improved vector potency.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Although", "...
PMC9105697	More lung metastases were resected in a second operation followed by adjuvant chemotherapy (sample 10 + 11) (Figure 4A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "More", ...
PMC11562028	It showed that the Re-CDs administration could induce significant changes in gene transcription levels in the A498 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "It", "showed", "that", "the", ...
PMC6160470	Previous studies demonstrated a positive UIC2 shift elicited by verapamil at 50 µM concentrations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Previous", "studies", "demonstrated", "a", "positive", "UIC2", "shift"...
PMC11200978	For instance, Snyder et al. and others have determined that the MLT for cardiac cells was −30 °C in vitro, and that translated directly to in vivo, wherein the MLT has been shown to be in the −25 °C to −30 °C range .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11502327	In addition, smart drug delivery platforms (20) have been developed in the field of nanocarriers, while clinical trials have demonstrated that nanoscale drug delivery systems are effective in improving the efficiency of cancer treatment (21).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The representative example of deep learning detection showed at figure.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "representative", "example", "of", "deep", "learning", "detection", "showed", "at", "figur...
PMC8567602	Data are presented as mean ± standard deviation unless otherwise noted.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "presented", "as", "mean", "±", "standard", "deviation", "unless", "oth...
PMC11551844	The plate was incubated for 72 hours at 37 °C in air with 5% CO2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "plate", "was", "incubated", "for", "...
PMC11075223	Total phenolic acid (20 mg/kg/d) markedly reduced the levels of hepatitis B surface antigen and hepatitis Be antigen in mice serum.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Total",...
PMC11740907	Results show a significant difference (p<0.05).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", "show", "a", "significant", "difference", "(", "p<0.05", ")", "." ] } ]
PMC11394386	Interaction probability between HOTAIR and transcriptional effectors (β-catenin and HIF1α) was analyzed using RPIseq.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interaction", "probability", "between", "HOTAIR", "and", ...
PMC11694066	Altogether, these results suggested that EWS–WT1 expression in JN1 cells increases replication stress, which is further exacerbated by PARPi and ATRi exposure.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11224020	The following secondary antibodies were used: Alexa Fluor 647 goat anti-rabbit (Invitrogen, A21244; 1:300) and Alexa Fluor 488 goat anti-mouse Fab2 (Invitrogen, A11017; 1:300).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11680578	Along with PPAR-γ, we have also studied the protein expression of β-actin and PPAR-α to normalize the expression of PPAR-γ.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Along", "with", "...
PMC9429973	Recently it has been implicated with a higher sensitivity in cancer stem cells and drug-resistant cancer cells, potentially making ferroptosis-inducing (FIN) therapies a promising option.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11462673	Initially characterized as a binding partner for LIM domain proteins, LDB1's role as a transcription cofactor is well-established, and its early loss during development leads to embryonic lethality .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6468656	In summary, the analytical results from the CCLE database revealed a significant association between ghrelin and Aurora A expression in ccRCC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "summar...
PMC11612794	Quantification data of GFP-Dsn1 signals at kinetochores in mitotic cells shown in (D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Quantification", "data", "of", "GFP-Dsn1", "signals", "at", ...
PMC10998613	Briefly, the custom-built Nikon confocal microscope (Eclipse Ti, Nikon Instruments) uses a 50 ns pulsed continuum white laser source (SuperK Extreme, NKT Photonics) that goes through a beam splitter (Spectrak Split, NKT Photonics) to split the beam into two wavelengths, 488 nm and 561 nm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11409031	Eiichi Sato et al. reported that CD8+T cells can eradicate OV cells and are associated with good patient survival .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Eiichi", "Sato", "et", "al.", ...
PMC11064533	A linear model was fitted to the data using moderated t-statistics, and log odds of differential expression were calculated by empirical Bayes moderation of the standard errors toward a global value using the limma package.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11352666	Similarly, BCL-2 inhibition with venetoclax increased sensitivity to nab-paclitaxel in highly resistant BCL-2-expressing EWS xenografts .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Similarly", ",", "BCL-2", "inhibition", "with", "venet...
PMC11402217	About 8 × 10ˆ2 143B and MG63 cells were cultured in a 6-well plate, with the medium enhanced by XD23 in concentrations ranging from 0.02 μM to 1.0 μM for 7 days post-adhesion.	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11323699	The left panel indicates the tumor response, with the dotted black circle representing mice unresponsive to olaparib treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "left", "panel", "indicates...
PMC9019892	To further ensure on‐target efficacy in GIST cell lines, we tested the response of the KIT‐mediated signalling pathway upon nintedanib treatment (Fig. 2C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11759751	However, the therapy still has many limitations, and many challenges and dilemmas remain .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "therapy", "still", "has", "many", ...
PMC11543885	False Positive Rate (FPR): Calculate the FPR, defined as the proportion of nucleolus and secreted proteins (based on Gene Ontology Cellular Component (GO-CC)) detected in your dataset.d.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11799978	CAFs can reciprocally promote tumor evasion and suppress immune cell functions by discharging lactic acid contributing to the overall acidity within the TME.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CAFs", ...
PMC11297139	ARID1A serves as a structural core and scaffold in the structural organization of the BAF complex, and C-terminal Pfam homology domain of ARID1A mediates direct molecular contact with other BAF subunits to maintain a stable base module of BAF complexes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10955424	Dasatinib (Src and Abl inhibitor) was used as well .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Dasatinib", "(", "Src", "and", "Abl", "inhibitor", ")", "was", "used", "as", "w...
PMC11628309	The ATCC recommends using FBS at a concentration of 10%, whereas the ECACC suggests a concentration of 15% (ATCC, CRL-2267, ECACC, 95011816).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11731614	Protein pellets were resuspended in 8 M urea (ThermoFisher Scientific, Cat # 29700) prepared in 100 mM ammonium bicarbonate solution (Fluka, Cat # 09830) and processed with ProteaseMAX (Promega, Cat # V2072) according to the manufacturer’s protocol.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10047551	Non-small-cell lung cancer (NSCLC) is a heterogeneous disease and, in approximately 20% of cases, characterized by oncogenic driver mutations in, e.g., EGFR, KRAS, and ALK .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9918897	Post hoc tests were not performed because there were fewer than three groups for each investigated factor.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Post", "hoc", "tests", "were", "not", "perf...
PMC10222971	Nevertheless, these results reveal certain selectivity, especially for derivative 4 with strong cytotoxicity on ovarian carcinoma cells and non-significant toxicity on non-tumoral HEK-293 cells, with values similar to the positive control etoposide.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "B-...
PMC11670407	In recent years, OTU deubiquitinase with linear linkage specificity (OTULIN) has been identified as a key linear deubiquitinating enzyme involved in cell death and inflammation .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Decreased HIF-1α levels were found in the MKs of patients with ITP, contributing to impaired PPF.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Decreased", "HIF-1α", "levels", "were", "found", ...
PMC11657695	The boxes indicate the first and third quartiles—and the midline represents the median—of the normalized KCNA2 mRNA expression determined by RT-qPCR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11544122	e, f SNX9 recruitment to CXCR4 by BRET in HEK293 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "e", ",", "f", "SNX9", "recruitment", "to", "CXCR4", "by", "BRET", ...
PMC7022782	On the basis of these results, further studies were conducted using the ICG-NPs1 formulation that showed for at least 1 month, both at room temperature and 4 °C, good physical stability in terms of dimensions and homogeneity of ICG dispersion.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11803918	They not only serve as efficient nanocarriers for drug delivery but also possess dual antitumor properties, targeting and eliminating tumor cells while boosting the antitumor T-cell immune response.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11767725	For example, TNF-α and IL-1β activate the NF-κB pathway, leading to the suppression of involucrin and loricrin transcription.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "example", ",", ...
PMC9429973	Incidence rates in the 3 waves were 8, 10.2 and 7 per 100 pt-yrs respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Incidence", "rates", "in", "the", "3", "waves", ...
PMC5941560	Homozygous deletions that lie in coding exons (red); 4.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Homozygous", "deletions", "that", "lie", "in", "coding", "exons", "(", "red", ...
PMC10362265	The binding interface of the human IL18-IL18BP heterodimer has overlapped with those formed with viral IL18BPs , , confirming the inhibition mechanism of host and viral IL18BPs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11298021	The spectrophotometer (MaestroNano Pro, Hong Kong) was employed to evaluate the quality and quantity of RNA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "spectrophotometer", "(", "...
PMC10759659	b Immune infiltration score by ESTIMATE.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "b", "Immune", "infiltration", "score", "by", "ESTIMATE", "." ] } ]
PMC10419319	A value of p < 0.05 was considered statistically significant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "value", "of", "p", "<", "0.05", "was", "considered", "statistically", "significant", ...
PMC9325715	Thus, there is the need for the comprehensive study of the formation mechanisms of the Fe-bLTF complex as well as its physicochemical and biological properties.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC5716223	e Proposed mechanism for NGF-p75 signaling pathways in L6C5 myogenic cells: during myoblast proliferation and serum-deprivation condition, the supplementation with NGF can sustain the activity of key enzymes in carbohydrate metabolism, such as citrate synthase and glyceraldehyde-phosphate-dehydrogenase, through the act...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11802855	Current research on the role of CXCL7 in tumors is limited.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Current", "research", "on", "the", "role", "of", "CXCL7", "in", "tumors", "is", ...
PMC5443223	Cells were stained with 2 µl Vybrant DyeCycle Green Stain and incubated at 37°C for 30 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "stained", "with"...
PMC11658074	After 8 weeks of UVB exposure, the AT group presented improved skin elasticity (Fig. 1b).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "8", "weeks", "of", "UVB", ...
PMC11566417	c Representative images of phase ring light microscopy of primary and immortalized MDECs adhering on a plastic plate at p10 and p20 at 10× and 20× magnification.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11532793	Analyses using legacy=TRUE are denoted as edgeR-v3 while the new pipeline with legacy=FALSE is denoted as edgeR-v4.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Analyses", "using", ...
PMC10366908	EMab-300 could contribute to the preclinical study to evaluate the antitumor effects and predict the side-effects of the EGFR-targeting therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "EMab-300", "could", "contrib...
PMC10993311	In this study, we observed DMRs and DMGMs enriched for biological processes, cellular components, and molecular functions resulting from EGWG.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC11676674	Conversely, the polar extracts contain a high concentration of polyphenols, flavonoids, tannins, and saponins, all possessing antioxidant properties .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Convers...
PMC3813807	MicroRNAs (miRNAs) are ~17–24 nucleotides long and act as negative regulators of gene expression by inhibiting mRNA translation or promoting mRNA degradation (5,6).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: To evaluate disease manifestation in terms of vaso-occlusive crisis (VOC) and SCD-related organ damage, as well as current management approaches, and to evaluate the clinically relevant information that can be captured from physician notes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9436459	The absolute structure of the cis–trans type adduct cathayanon A (136) was confirmed by X-ray crystallographic analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "absolute", ...
PMC9429973	It is shown, that plasmacytoma cells are the descendants of bone marrow tumor plasma cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "shown", ",", "that", "plasmacytoma", ...
PMC11655536	C The cell viability of ARH-77 R treated with HA at the indicated concentration for 48 h. D Apoptosis assay of ARH-77 R treated with HA at 48 h. The percentage of apoptotic cells (Annexin-V + PI + ) after treatment was analyzed by the flow cytometry.	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "...
PMC9429973	Median duration of response will be reported.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Median", "duration", "of", "response", "will", "be", "reported", "." ] } ]
PMC7338939	Notably, the exclusive dose of DAPT was calculated for every animal.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notably", ",", "the", "exclusive", "dose", "of", "DAPT", "was", "calculated", ...
PMC9429973	Patients with active MM had signficantly worse outcome of Covid19 infection, (Chi-Square, p=0.003).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "with", "active", "MM", "had", "...
PMC11715644	Within cell clusters, where cells are usually constrained by neighbouring cells, individual cell motions are coupled with their neighbours.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Within", "cell", ...
PMC7192625	and network statistics (average degree, size of connected component etc.)	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "and", "network", "statistics", "(", "average", "degree", ",", "size", ...
PMC9429973	Continuous administration of E-PAG could improve the hematological response of PR patients to CR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Continuous", "administration", "of", "E-PAG", "could", "improve", "the...

PMC6337547

The biosynthetic pathways of polyphenols include the shikimic acid and phenylpropanoid metabolism pathways .

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PMC6901583

The transfection of the pcDNA-3.1(+)-BRD4 vector led to increased BRD4 in the GIST-882 and GIST-T1 cell lines compared with the transfection of pcDNA-3.1(+) alone (Fig. 2a).

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PMC9429973

Median overall survival (mOS) was 62.5 mo (95% CI, 51.7−NR; 5-y PFS and OS rates, 24% and 52%).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11770130

The phospho-proteomics analysis on the eWATs from lean control and Ntsr2 AKO mice with comparable body weight identified significant changes in the phosphorylation of multiple proteins (Fig. 3a; Supplementary information, Table S1).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8916024

In snails, the gut is the main site for nutrient absorption and utilization (Pawar et al., 2012; Dar, Pawar & Pandit, 2017).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11694625

The IC50 values were calculated according to the inhibition rate at a different concentration.

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PMC9429973

Median Ferritin was 322 ng/ml (range 17-1236) and median Alkaline Phosphatase was 81 U/L (range 29-355).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC9878562

Under these conditions blood endothelial cells die and the remaining cells are composed of fibroblastic reticular cells (FRCs) (~40%) and LECs.

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PMC11806818

Reprinted with permission from As a gynecological malignancy, cervical cancer occurs mostly in young patients .

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PMC11337594

B, C) A375 and GSDME-KO cells were treated with different doses (0, 1.0, 2.0 and 3.0 µg/ml) of TER for 24 h, followed by Annexin V-FITC/PI staining and flow cytometry analysis (n = 4).

[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...

PMC9429973

Conditioning regimen was reduced intensity in 78.6% (n=11) and myeloablative in 24.6% (n=3).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Conditioning", "regimen", "was", ...

PMC9429973

Although haemoglobin (Hb) levels have been found to be correlated to QoL, it is widely reported that other factors are important in determining QoL and need for transfusions can vary despite a stable Hb level.

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PMC9777812

With Western blot analysis, the same expression trends of CDKN1A gene were found at the protein level (Figure 3E,F).

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PMC9429973

At a median follow up of 16.2 months (range 9-29 months), 9/10 patients are alive and in CR with no chronic GvHD.

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PMC11634794

Additionally, LAMP1 was identified as a direct target responsible for UBL4A-induced tumor suppression and autophagy inhibition.

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PMC9429973

The median CSF concentration of orelabrutinib was 28.7ng/ml (rang 11.8 ng/ml to 52.7 ng/ml).

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PMC11472639

indicates a significant difference from post-exercise at p < 0.01.

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PMC11348300

This consistency further substantiates the utility of PpIX fluorescence in capturing oxygen dynamics and highlights its potential as a valuable tool in elucidating intricate cellular oxygenation processes.

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PMC11471157

Furthermore, immunostaining with αSMA indicated that only a small fraction of cells differentiated into myofibroblasts, with the majority of NIH/3T3 cells testing negative for αSMA (Fig. 3I).

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PMC11621493

Statistically significant differences are shown as: ∗P < 0.05; ∗∗P < 0.01; and ∗∗∗P < 0.001.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistically", "significant", "differe...

PMC10745221

A protein with SDMA near 15 kDa was also detected in the 143B lysates in Fig 2.

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PMC10589262

ATF6 activation was frequently observed in 67% of patients with GIST (n = 42), and was significantly associated with poorer relapse-free survival (P = 0.033).

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PMC11224206

This means that for a temperature shift of 10 °C, the metabolic rate will double or halve, and for a change of ~ 1 °C, i.e. the minimum order of magnitude being considered here, 10%.

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PMC9412887

41.6 °C.

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PMC8193046

For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)Fig.

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PMC10222971

Therefore, a flow cytometric assay of Annexin V/PI was conducted to quantify the apoptotic profile in quinone-treated IGROV-1 cells.

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PMC9599726

The DAB-Ni solution was prepared by dissolving 0.06 g of nickel ammonium sulfate (Fluka, Buchs, Switzerland, Cat# 09885) and 2 mg of DAB (Sigma-Aldrich, St. Louis, MO, USA, Cat# D5637) in 10 mL of 0.05 M Tris/HCl, pH 8.

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PMC10178190

The HGF/MET axis was reported as a potential key contributor to promoting chemoresistance in cancer cells .

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PMC11435360

To evaluate tumor growth following intravesical therapy, the mice underwent a second scan on week 19.

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PMC11544122

Endocytosis was calculated as a fractional decrease in cell surface receptors in CXCL12-treated cells compared with vehicle-treated cells after background subtraction, which was assessed in parallel using an isotype control antibody.

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PMC8711270

Although only serotypes AAV1 and AAV8 were tested, this suggests that HEK293-produced rAAVs are preferred due to the improved vector potency.

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PMC9105697

More lung metastases were resected in a second operation followed by adjuvant chemotherapy (sample 10 + 11) (Figure 4A).

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PMC11562028

It showed that the Re-CDs administration could induce significant changes in gene transcription levels in the A498 cells.

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PMC6160470

Previous studies demonstrated a positive UIC2 shift elicited by verapamil at 50 µM concentrations.

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PMC11200978

For instance, Snyder et al. and others have determined that the MLT for cardiac cells was −30 °C in vitro, and that translated directly to in vivo, wherein the MLT has been shown to be in the −25 °C to −30 °C range .

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PMC11502327

In addition, smart drug delivery platforms (20) have been developed in the field of nanocarriers, while clinical trials have demonstrated that nanoscale drug delivery systems are effective in improving the efficiency of cancer treatment (21).

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PMC9429973

The representative example of deep learning detection showed at figure.

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PMC8567602

Data are presented as mean ± standard deviation unless otherwise noted.

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PMC11551844

The plate was incubated for 72 hours at 37 °C in air with 5% CO2.

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PMC11075223

Total phenolic acid (20 mg/kg/d) markedly reduced the levels of hepatitis B surface antigen and hepatitis Be antigen in mice serum.

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PMC11740907

Results show a significant difference (p<0.05).

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PMC11394386

Interaction probability between HOTAIR and transcriptional effectors (β-catenin and HIF1α) was analyzed using RPIseq.

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PMC11694066

Altogether, these results suggested that EWS–WT1 expression in JN1 cells increases replication stress, which is further exacerbated by PARPi and ATRi exposure.

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PMC11224020

The following secondary antibodies were used: Alexa Fluor 647 goat anti-rabbit (Invitrogen, A21244; 1:300) and Alexa Fluor 488 goat anti-mouse Fab2 (Invitrogen, A11017; 1:300).

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PMC11680578

Along with PPAR-γ, we have also studied the protein expression of β-actin and PPAR-α to normalize the expression of PPAR-γ.

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PMC9429973

Recently it has been implicated with a higher sensitivity in cancer stem cells and drug-resistant cancer cells, potentially making ferroptosis-inducing (FIN) therapies a promising option.

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PMC11462673

Initially characterized as a binding partner for LIM domain proteins, LDB1's role as a transcription cofactor is well-established, and its early loss during development leads to embryonic lethality .

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PMC6468656

In summary, the analytical results from the CCLE database revealed a significant association between ghrelin and Aurora A expression in ccRCC.

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PMC11612794

Quantification data of GFP-Dsn1 signals at kinetochores in mitotic cells shown in (D).

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PMC10998613

Briefly, the custom-built Nikon confocal microscope (Eclipse Ti, Nikon Instruments) uses a 50 ns pulsed continuum white laser source (SuperK Extreme, NKT Photonics) that goes through a beam splitter (Spectrak Split, NKT Photonics) to split the beam into two wavelengths, 488 nm and 561 nm.

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PMC11409031

Eiichi Sato et al. reported that CD8+T cells can eradicate OV cells and are associated with good patient survival .

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PMC11064533

A linear model was fitted to the data using moderated t-statistics, and log odds of differential expression were calculated by empirical Bayes moderation of the standard errors toward a global value using the limma package.

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PMC11352666

Similarly, BCL-2 inhibition with venetoclax increased sensitivity to nab-paclitaxel in highly resistant BCL-2-expressing EWS xenografts .

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PMC11402217

About 8 × 10ˆ2 143B and MG63 cells were cultured in a 6-well plate, with the medium enhanced by XD23 in concentrations ranging from 0.02 μM to 1.0 μM for 7 days post-adhesion.

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PMC11323699

The left panel indicates the tumor response, with the dotted black circle representing mice unresponsive to olaparib treatment.

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PMC9019892

To further ensure on‐target efficacy in GIST cell lines, we tested the response of the KIT‐mediated signalling pathway upon nintedanib treatment (Fig. 2C).

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PMC11759751

However, the therapy still has many limitations, and many challenges and dilemmas remain .

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PMC11543885

False Positive Rate (FPR): Calculate the FPR, defined as the proportion of nucleolus and secreted proteins (based on Gene Ontology Cellular Component (GO-CC)) detected in your dataset.d.

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PMC11799978

CAFs can reciprocally promote tumor evasion and suppress immune cell functions by discharging lactic acid contributing to the overall acidity within the TME.

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PMC11297139

ARID1A serves as a structural core and scaffold in the structural organization of the BAF complex, and C-terminal Pfam homology domain of ARID1A mediates direct molecular contact with other BAF subunits to maintain a stable base module of BAF complexes.

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PMC10955424

Dasatinib (Src and Abl inhibitor) was used as well .

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PMC11628309

The ATCC recommends using FBS at a concentration of 10%, whereas the ECACC suggests a concentration of 15% (ATCC, CRL-2267, ECACC, 95011816).

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PMC11731614

Protein pellets were resuspended in 8 M urea (ThermoFisher Scientific, Cat # 29700) prepared in 100 mM ammonium bicarbonate solution (Fluka, Cat # 09830) and processed with ProteaseMAX (Promega, Cat # V2072) according to the manufacturer’s protocol.

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PMC10047551

Non-small-cell lung cancer (NSCLC) is a heterogeneous disease and, in approximately 20% of cases, characterized by oncogenic driver mutations in, e.g., EGFR, KRAS, and ALK .

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PMC9918897

Post hoc tests were not performed because there were fewer than three groups for each investigated factor.

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PMC10222971

Nevertheless, these results reveal certain selectivity, especially for derivative 4 with strong cytotoxicity on ovarian carcinoma cells and non-significant toxicity on non-tumoral HEK-293 cells, with values similar to the positive control etoposide.

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PMC11670407

In recent years, OTU deubiquitinase with linear linkage specificity (OTULIN) has been identified as a key linear deubiquitinating enzyme involved in cell death and inflammation .

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PMC9429973

Decreased HIF-1α levels were found in the MKs of patients with ITP, contributing to impaired PPF.

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PMC11657695

The boxes indicate the first and third quartiles—and the midline represents the median—of the normalized KCNA2 mRNA expression determined by RT-qPCR.

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PMC11544122

e, f SNX9 recruitment to CXCR4 by BRET in HEK293 cells.

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PMC7022782

On the basis of these results, further studies were conducted using the ICG-NPs1 formulation that showed for at least 1 month, both at room temperature and 4 °C, good physical stability in terms of dimensions and homogeneity of ICG dispersion.

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PMC11803918

They not only serve as efficient nanocarriers for drug delivery but also possess dual antitumor properties, targeting and eliminating tumor cells while boosting the antitumor T-cell immune response.

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PMC11767725

For example, TNF-α and IL-1β activate the NF-κB pathway, leading to the suppression of involucrin and loricrin transcription.

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PMC9429973

Incidence rates in the 3 waves were 8, 10.2 and 7 per 100 pt-yrs respectively.

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PMC5941560

Homozygous deletions that lie in coding exons (red); 4.

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PMC10362265

The binding interface of the human IL18-IL18BP heterodimer has overlapped with those formed with viral IL18BPs , , confirming the inhibition mechanism of host and viral IL18BPs.

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PMC11298021

The spectrophotometer (MaestroNano Pro, Hong Kong) was employed to evaluate the quality and quantity of RNA.

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PMC10759659

b Immune infiltration score by ESTIMATE.

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PMC10419319

A value of p < 0.05 was considered statistically significant.

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PMC9325715

Thus, there is the need for the comprehensive study of the formation mechanisms of the Fe-bLTF complex as well as its physicochemical and biological properties.

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PMC5716223

e Proposed mechanism for NGF-p75 signaling pathways in L6C5 myogenic cells: during myoblast proliferation and serum-deprivation condition, the supplementation with NGF can sustain the activity of key enzymes in carbohydrate metabolism, such as citrate synthase and glyceraldehyde-phosphate-dehydrogenase, through the act...

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PMC11802855

Current research on the role of CXCL7 in tumors is limited.

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PMC5443223

Cells were stained with 2 µl Vybrant DyeCycle Green Stain and incubated at 37°C for 30 min.

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PMC11658074

After 8 weeks of UVB exposure, the AT group presented improved skin elasticity (Fig. 1b).

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PMC11566417

c Representative images of phase ring light microscopy of primary and immortalized MDECs adhering on a plastic plate at p10 and p20 at 10× and 20× magnification.

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PMC11532793

Analyses using legacy=TRUE are denoted as edgeR-v3 while the new pipeline with legacy=FALSE is denoted as edgeR-v4.

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PMC10366908

EMab-300 could contribute to the preclinical study to evaluate the antitumor effects and predict the side-effects of the EGFR-targeting therapy.

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PMC10993311

In this study, we observed DMRs and DMGMs enriched for biological processes, cellular components, and molecular functions resulting from EGWG.

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PMC11676674

Conversely, the polar extracts contain a high concentration of polyphenols, flavonoids, tannins, and saponins, all possessing antioxidant properties .

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PMC3813807

MicroRNAs (miRNAs) are ~17–24 nucleotides long and act as negative regulators of gene expression by inhibiting mRNA translation or promoting mRNA degradation (5,6).

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PMC9429973

Aims: To evaluate disease manifestation in terms of vaso-occlusive crisis (VOC) and SCD-related organ damage, as well as current management approaches, and to evaluate the clinically relevant information that can be captured from physician notes.

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PMC9436459

The absolute structure of the cis–trans type adduct cathayanon A (136) was confirmed by X-ray crystallographic analysis.

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PMC9429973

It is shown, that plasmacytoma cells are the descendants of bone marrow tumor plasma cells.

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PMC11655536

C The cell viability of ARH-77 R treated with HA at the indicated concentration for 48 h. D Apoptosis assay of ARH-77 R treated with HA at 48 h. The percentage of apoptotic cells (Annexin-V + PI + ) after treatment was analyzed by the flow cytometry.

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PMC9429973

Median duration of response will be reported.

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PMC7338939

Notably, the exclusive dose of DAPT was calculated for every animal.

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PMC9429973

Patients with active MM had signficantly worse outcome of Covid19 infection, (Chi-Square, p=0.003).

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PMC11715644

Within cell clusters, where cells are usually constrained by neighbouring cells, individual cell motions are coupled with their neighbours.

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PMC7192625

and network statistics (average degree, size of connected component etc.)

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PMC9429973

Continuous administration of E-PAG could improve the hematological response of PR patients to CR.

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