OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC11610461	The representative PSENEN immunohistochemical staining in KIRC tissues (G1: n = 6, G2: n = 10, G3: n = 5, G4: n = 2). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6650823	With the use of small-molecule CFTR potentiators, it may be possible to correct the defective CFTR channel in patients with specific CFTR mutations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	An estimated 84% of complete responders and 61% of responders remained in response at 9 months.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", "estimated", "84", "%", "of", ...
PMC11676670	Although TP53 mutations are present in approximately 96% of high-grade serous ovarian cancer cases, no mutations were detected in the hotspot regions of exons 3–8 within the OVAR79 cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11731161	The sensitivity of MM cell lines to SEL was evaluated using CCK8-based cell viability assays and AV-PI staining-based cell apoptosis assays.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "sensitivity", ...
PMC11655536	These data suggest the potential important role of NHE1 in MM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "data", "suggest", "the", "potential", "important", "role", "of", "NHE1", "in...
PMC9611901	It is important to note that repair of these lesions leads to DNA excision , resulting in additional “repair-related” primary DNA damage that can be detected by the alkaline comet assay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Methods: We enrolled 60WHO-defined PV patients (30 men, 30 women; mean age 45±10 years) without cardiovascular risk factors, autoimmune disease or thrombotic history.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7759933	We further investigated the transcription level of the HIF1α gene, one of the hypoxia-inducible factors, which mediates cellular adaptation to hypoxic conditions .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11792090	In summary, our pre-clinical studies demonstrate that SAP UCAR-T cells exhibit low immunogenicity, satisfactory persistence, and robust anti-solid tumor activity, along with reduced safety concerns both in vitro and in vivo.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11766332	Out of the most relevant gene nodes, we identified the glycogene B4GALT1 with high values of connectivity and degree (Supplementary Table S3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC7709199	The electron density allows the modeling of a Man4GlcNAc2 glycan.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "electron", "density", "allows", "the", "modeling", "of", "a", "Man4GlcNAc2", "glycan", ...
PMC6642070	To understand the underlying mechanisms of statin-induced p53 down-regulation, we first measured the mRNA levels of p53 in A-204 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "To", "understa...
PMC11629143	Routine culture was in Ham's F12 medium with 10% fetal calf serum, 4 mM GlutaMAX (Sigma Aldrich), and 1% penicillin/streptomycin in T flasks at 37°C with 5.4% CO2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11705630	To test this hypothesis, we used anticancer drugs Dox and CP to induce DNA damage in ACHN and Caki-2 cells and determined whether GLDC knockdown affects cell viabilities in Dox/or CP-treated RCC cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "...
PMC11583010	Nonparametric tests were used according to the comparison setting (Mann–Whitney or Kruskal–Wallis and Dunn multiple comparison tests).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Nonpara...
PMC10443665	CCRF-CEM/MTX subline is the CCRF-CEM cells exposed to MTX 0.1 μM (MTX IC50) for 48 h. It should be noted that the IC50 of MTX was determined using different concentrations of it on CCRF-CEM cells through MTT assay (Fig. 1).	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11467964	As shown in the waterfall map, 38 of 238 (15.97%) patients had mutations in these genes (Supporting Information S1: Figure S1), among which the top five mutated genes with their mutation frequencies were ACAN (3%), COL4A1 (2%), COL6A3 (2%), FBN2 (2%), and TNC (2%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9596868	p ≤ 0.05; p ≤ 0.01; p ≤ 0.001; ***p ≤ 0.0001 represent significant changes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Methods: We investigated the effect of small molecule inhibitor of TP53 mutation (APR-246) in combination with decitabine on the proliferation of MDS/AML cells (SKM-1, NB4 and KASUMI-1) which carries the recurrent homozygous TP53 mutation p.R248Q (TP53 ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9261184	To ensure consistent FTIR performance throughput the testing period, the FTIR system was calibrated with reference gases once per day.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "ensure", "c...
PMC11473750	Positive (amplified) and negative (non-amplified) controls were included in each FISH run.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Positive", "(", "amplified", ")", "and", "negative", ...
PMC10723784	Therefore, it may be suggested that in ovarian cancer cannabinoids also induce cellular processes involving ROS signaling, which may be due to an impaired mitochondrial function.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11448304	In recent years, an increasing number of studies have focused on cancer lysine acetylation, such as esophageal squamous cell carcinoma , lung adenocarcinoma , gastric cancer and pancreatic cancer .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11754784	j Simulated reaction rate of different layers with or without considering the “diffusion trap” theory.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "j", "Simulated", "reaction", "rate", "of", ...
PMC8540692	CCM and NaBu are natural compounds with anticancer effects and minimal toxicity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CCM", "and", "NaBu", "are", "natural", "compounds", "with", "anticancer", "effec...
PMC11106977	Hao et al. provided evidence that the expression levels of Notch signaling-activated genes, Rbpj and Hes1, were significantly induced in wild-type (Eogt) CD4 T cells but not in Eogt knockout (Eogt) counterparts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Intravenous carfilzomib was given in a dose of 20 mg/m in cycle 1 day 1, and thereafter 56 mg/m (DL1-4) and 70 mg/m (DL5) on day 8, 15, and in all subsequent cycles and doses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11277157	There are 76 antioxidant activity annotated genes (GO: 0016209; Supplementary Figure S1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "are", "76", "antioxidant", "activity", "annot...
PMC10470467	And, according to calibration plots, we found that the mortality estimated by the nomogram was close to the actual mortality (Figure 9D), confirming the nomogram’s excellent accuracy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11509224	Notably, the genera Spongia, Agelas, and Acanthella reported the highest number of diterpenes, with counts of 62, 33, and 17, respectively, accounting for 27%, 14%, and 7% of the total reported molecules, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: To report the preliminary safety, tolerability, and initial antitumor efficacy of CB-010.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "To", "report", "the", "preliminary", ...
PMC11351758	Another research group reported that when catalase removed free radicals from the mitochondria, a 10% increment in the lifespan of the mouse was recorded, and they projected that similar results would be achieved in humans; however, there are currently no clinical trials to support this claim .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11422497	We have underscored its significant upregulation and unveiled its oncogenic function in GISTs, where it acts by sequestering miR-494-3p, thereby activating the KIT/JAK/STAT pathway.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11665584	Both ALDH3A1 and Aldh1a3 facilitate the critical step of converting retinal to bioactive RA within cells (63).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Both", "ALDH3A1", "and", "Aldh1a3...
PMC11514418	A total of 97 patients were included in the retrospective study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "total", "of", "97", "patients", "were", "included", "in", "the", "retrospective"...
PMC11594806	Additionally, ALMB-0168 increases cytotoxic lymphocyte levels (CD3/CD8+ T cells) and helper T-cell levels (CD3/CD4+), improves survival rates, and reduces tumor metastasis .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3019555	In contrast, only background fluorescence was observed upon coincubation with a sense DNA ODN (Fig. 3 A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "contrast", ",", ...
PMC11576293	For C18H16ClN2OS (M + H) 343.06664; found 343.06726.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "C18H16ClN2OS", "(", "M", "+", "H", ")", "343.06664", ";", "found", "343....
PMC9429973	The median time from auto-HCT to VOD/SOS diagnosis was 14.0 (range: 0, 185) days.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "median", "time", "from", "auto-...
PMC9351137	In telophase, all the tested CRS were found at the midbody.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "telophase", ",", "all", "the", "tested", "CRS", "were", "found", "at...
PMC6461034	The other cell lines were cultured in RPMI 1640 containing 2 mM L‐glutamine and supplemented with 10% fetal bovine serum (K562 as a suspension culture).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", ...
PMC11585994	Each group received the corresponding nanoparticle formulation via intravenous injection through the tail vein.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "group", "received", "the", "corresponding", "nanoparticle", "f...
PMC11790971	The error bars represent the standard deviations of balanced accuracies at each iteration of RFE.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "error", "bars", "represent", "the", "standard", "dev...
PMC9429973	On the etiological assessment, protein electrophoresis objectified a monoclonal peak with the presence of an immunoglobulin G kappa at immunofixation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "On", "the", "etio...
PMC6835428	PARP mediates base excision repair of single-strand breaks to resolve spontaneous DNA damage .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PARP", "mediates", "base", "excision", "repair", "of", "single-strand", "br...
PMC11489175	A role for deubiquitinases (DUBs) is starting to emerge in ovarian cancer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "role", "for", "deubiquitinases", "(", "DUBs", ")", "is", ...
PMC11525028	AG-401: 2.5 mg/kg daily, i.p.) (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "AG-401", ":", "2.5", "mg/kg", "daily", ",", "i.p", ".", ")", "(" ] } ]
PMC9436459	A., Artocarpus; B., Brosimopsis; B.*, Brosimum; C., Chlorophora; D., Dorstenia; M., Morus; S., Sorocea.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Animals were transfused when Hb dropped ≤5,5 g/dL. Results: Eight weeks after FLT, BM Tfr2 deletion improved anemia of Hbb mice with a gene-dosage effect, increasing RBC count and Hb levels and reducing the percentage of circulating reticulocytes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The most commonly reported adverse events (AEs) of any grade were nausea (6/31,19.4%), elevated liver transaminases (4/31,12.9%), and headache (3/31,9.7%); no severe AEs had been reported until the cutoff date.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9884169	Meanwhile, GEPIA database analysis showed that the long-term survival of bladder cancer patients with high expression of MCT4 was significantly lower than that of bladder cancer patients with low expression of MCT4, which suggested that MCT4 may be a potential target for bladder cancer therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8557138	Freedman et al. demonstrated the construction of genetically modified kidney organoids to study genetic kidney disease (Freedman et al. 2015).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Freedman", "...
PMC11714165	The standard IκB kinase (IKK) complex activates the NF‐κB pathway, with NF‐κB essential modulator (NEMO) acting as a regulatory subunit by interacting with both IKKα and IKKβ.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10798140	The novel quinoline derivative (compound 91b1) developed by Yuan Zhou demonstrated antitumor efficacy in nude mice via downregulation of lumican.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "novel...
PMC10218459	A corresponding second plate was treated in parallel to normalize the absorption values to cell numbers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "corresponding", "second", "plate", "was", "treate...
PMC11243198	In our study, we aimed to identify novel and potent GLI antagonists with potentially improved physicochemical properties.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "our", "study", ",", "we", ...
PMC11537649	The experimental procedure was conducted following the protocol of the manuscript of the EZ-Magna RIP kit (#17–295, Millipore, Billerica, MA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973	Overall, median CS dose decreased over time in the RUX and BAT arms and was similar between groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overall", ",", "median", "CS", ...
PMC10854447	Antiproliferative activity of compounds 7a–o and Erlotinib.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Antiproliferative", "activity", "of", "compounds", "7a", "–", "o", "and", "Erlotinib", "." ] } ]
PMC7823217	Along with malignant cells, stromal cells of breast cancer also greatly influence the progression of tumor by altering the cells phenotypes, secreting signaling molecules and reorganizing themselves to support tumor invasion (Fig. 3-A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11488203	A potential clinical use of MSC-derived EVs/exosomes is attractive as a cell-free system due to a reasonable biocompatibility and a reduced immunogenicity as compared to a cellular system.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11711127	The main APC for T cells are DCs, which exist in different states including operationally defined tolDC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "main", "APC", "for", "T", ...
PMC11746942	A Western blot analysis of S1PR3 expression in HaCaT cells treated with increasing concentrations of IL-6 (top) or IL-22 (bottom).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "token...
PMC10747160	Contrary to expectations, we observed a similar phenomenon as described for WT-Grft: GLG-3A consistently appeared to enhance Raji DC-SIGN+ SARS-CoV-2 pseudoviral infectivity by at least 1 order of magnitude (Figure 4D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", ...
PMC11766309	In addition, the independent prognostic value of YKT6 was analyzed via a K‒M plot.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "the", "independent", "prognostic", "...
PMC11286266	Treatment with DTT for 1 hr (4 mM) was used to induce ATF6α processing.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Treatment", "with", "DTT", "for", "1", "hr", "("...
PMC7185206	Our findings further support that pre-treatment tumor expression of PD-L1 by immunohistochemistry is insufficient to determine whether a patient may benefit from a PD-(L)1 inhibitor.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10993311	Descriptive statistics were used for data analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Descriptive", "statistics", "were", "used", "for", "data", "analysis", "." ] } ]
PMC9429973	AZA was administered every 21 days (d) for 4 cycles (cy), with the following schedule: 55 mg/m for 5 d, 55 mg/m for 7 d, 75 mg/m for 5 d, 75 mg/m for 7 d, respectively; prednisone 1 mg/m was associated to each cycle.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8567602	To test the tumorigenic potential of Smarcb1 loss alone in mesenchyme, we injected TATCre protein into the paws of mice homozygous for a conditional disruption allele of Smarcb1 (5).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10125312	A suspension of 8 × 10 cells in 20 μL on a 96-well plate (Round bottom, Corning 3879, Corning Inc.) was irradiated from the top with a 3 mm diameter cw collimated laser beam from a Ti:sapphire laser (LU0808D 180 diode laser, LuOcean Mini, Lumics GmbH) adjusted to a wavelength of 808 nm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11400680	We intentionally used this idea with the aim of capturing all potential prompts for cells and nuclei, thereby reducing the probability of missed detections.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11609529	We show that the YM fusion forms nuclear condensates, interacts with the TEAD transcription factors, and activates YAP1/TEAD-mediated transcription.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "show", "tha...
PMC11787381	Some of the methods studied include enhancing NE signaling in the brain through the use of β2-AR agonists, among which terbutaline has been found to prevent the Aβ mediated inhibition of Long-Term Potentiation (LTP).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11351758	Severely depleted or peroxidized CL can enhance the opening of the mPTP, which could meet the minimum threshold for Ca and thus further enhance and potentiate mCa toxicity in the opening of the mPTP.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11718109	The N2 medium is comprised of Neurobasal Plus media (Thermo Fisher Scientific), 2% B27 supplement without vitamin A (Thermo Fisher Scientific), 1% N2 supplement, 1% glutaMAX and 0.2% penicillin-streptomycin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	There were 365 (6.1%) VTE, among them 137 (2.3%) DVT and 262 (4.4%) PE.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11391695	A concurrent and substantial decrease in both the quantity and mass of tumors was identified (Fig. 7D, E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "concurrent", ...
PMC11626627	In our previous study, we found that overexpression of circATP2B1 inhibited the invasion of ccRCC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "our", "previous", "study", ",", "we", "fou...
PMC11594074	Imaging was carried out using an AF7000 Widefield Fluorescence Microscope (Leica, Wetzlar, Germany) (40× magnification) at the green channel (488/510 nm) and DAPI (358/461 nm) in order to determine KI-67 localization and expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10565698	Western blotting results confirmed the elevation in E-cadherin expression and the decrease in N-cadherin and vimentin expression after the dysregulation of circUSP10 expression (Fig. 3I).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9596868	Table 1A: Combination index for quercetin with chemotherapeutic drugs/compounds in cancer cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Table", "1A", ":", "Combination", "index", "for", "quercetin", "...
PMC11243198	Purmorphamine was purchased from Cayman Chemical (Ann Arbor, MI, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Purmorphamine", "was", "purchased", "from", "Cayman", "Chemical", "(",...
PMC9429973	In contrast, the antiviral foscarnet was not associated with mutations in HSCs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "contrast", ",", "the", "antiviral", "foscarnet", "was", "not", ...
PMC11471157	Medaka was the only fish species used, and it is necessary to verify whether similar effects are observed in other small fish species to confirm the advantages of this microcarrier for cell culture.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Methods: Pts were randomized 1:1 to receive up to 6 cycles of A+AVD (n=664) or ABVD (n=670) on day 1 and 15, every 28 days.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11679892	A similar trend was observed during the 48 h incubation period, and it was determined that the cytotoxic effect of P. sidoides continued stably as time progressed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11506827	The gintonin-enriched Panax ginseng extract fraction (GEF) has diverse pharmacological benefits.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "gintonin-enriched", "Panax", "ginseng", "extract", "fraction", "(", ...
PMC11783017	Benefiting from the high ROS levels in the tumor microenvironment, ROS-responsive hydrogel-based nanomedicines offer an alternative approach for local drug delivery, achieving precise and sustained drug release via intratumoral injection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11354225	Cells were seeded in T25 flasks.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "seeded", "in", "T25", "flasks", "." ] } ]
PMC9917080	The effect of SeNPs and SeSo increased after 48 h of incubation with cells, which correlated with the depletion of the Ca pool of the endoplasmic reticulum.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11615218	With comprehensive insight into the biological processes underlying successful CAR-T cell therapy, we will further refine the applications of these novel therapeutic modalities, and enhance their efficacy and safety for patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10631132	After EB induction, cells were fixed with 4% paraformaldehyde (PFA) and blocked with PBS containing 10% normal goat serum (Abcam, Cambridge, UK), 0.3% Triton X-100 (Sigma-Aldrich, St. Louis, MO, USA), and 1% bovine serum albumin (BSA) (Sigma-Aldrich, St. Louis, MO, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11723210	By comparing with the results from digital holography, we verified the accuracy of the QPI results, especially for samples with large phase values.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC3765139	The aim of the study was to identify CSC markers potentially allowing the functional characterization of specific cell subsets from clinical specimens, which have been identified in different types of tumors, including melanoma .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11798926	p < 0.05; p < 0.01; p < 0.001; ***p < 0.0001.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC7759933	Long-term cultivation of HepG2 cells in 3D conformation led to the enhancement of the expression of liver-specific markers, as shown for alpha-fetoprotein (AFP) and albumin (ALB) compared to monolayer culture (Figure 4).	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11298021	In contrast, transfection of Jurkat cells with miR-3143 or miR-3182 and subsequent treatment with rapamycin resulted in a significant decrease in the mRNA expression of PI3K, AKT, mTOR, and S6KB1 genes.	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8427838	D Whole cell lysates (WCL) derived from HEK-293 cells expressing empty vector (EV), GFP-tagged moesin (MSN-GFP) or GFP-tagged ezrin were incubated with GST, GST-TMIGD1 or GST-4A-TMIGD1 followed by western blot analysis using an anti-GFP antibody.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11610461

The representative PSENEN immunohistochemical staining in KIRC tissues (G1: n = 6, G2: n = 10, G3: n = 5, G4: n = 2). (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC6650823

With the use of small-molecule CFTR potentiators, it may be possible to correct the defective CFTR channel in patients with specific CFTR mutations.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC9429973

An estimated 84% of complete responders and 61% of responders remained in response at 9 months.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", "estimated", "84", "%", "of", ...

PMC11676670

Although TP53 mutations are present in approximately 96% of high-grade serous ovarian cancer cases, no mutations were detected in the hotspot regions of exons 3–8 within the OVAR79 cells .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11731161

The sensitivity of MM cell lines to SEL was evaluated using CCK8-based cell viability assays and AV-PI staining-based cell apoptosis assays.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "sensitivity", ...

PMC11655536

These data suggest the potential important role of NHE1 in MM.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "data", "suggest", "the", "potential", "important", "role", "of", "NHE1", "in...

PMC9611901

It is important to note that repair of these lesions leads to DNA excision , resulting in additional “repair-related” primary DNA damage that can be detected by the alkaline comet assay.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Methods: We enrolled 60WHO-defined PV patients (30 men, 30 women; mean age 45±10 years) without cardiovascular risk factors, autoimmune disease or thrombotic history.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7759933

We further investigated the transcription level of the HIF1α gene, one of the hypoxia-inducible factors, which mediates cellular adaptation to hypoxic conditions .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11792090

In summary, our pre-clinical studies demonstrate that SAP UCAR-T cells exhibit low immunogenicity, satisfactory persistence, and robust anti-solid tumor activity, along with reduced safety concerns both in vitro and in vivo.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11766332

Out of the most relevant gene nodes, we identified the glycogene B4GALT1 with high values of connectivity and degree (Supplementary Table S3).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC7709199

The electron density allows the modeling of a Man4GlcNAc2 glycan.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "electron", "density", "allows", "the", "modeling", "of", "a", "Man4GlcNAc2", "glycan", ...

PMC6642070

To understand the underlying mechanisms of statin-induced p53 down-regulation, we first measured the mRNA levels of p53 in A-204 cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "To", "understa...

PMC11629143

Routine culture was in Ham's F12 medium with 10% fetal calf serum, 4 mM GlutaMAX (Sigma Aldrich), and 1% penicillin/streptomycin in T flasks at 37°C with 5.4% CO2.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11705630

To test this hypothesis, we used anticancer drugs Dox and CP to induce DNA damage in ACHN and Caki-2 cells and determined whether GLDC knockdown affects cell viabilities in Dox/or CP-treated RCC cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "...

PMC11583010

Nonparametric tests were used according to the comparison setting (Mann–Whitney or Kruskal–Wallis and Dunn multiple comparison tests).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Nonpara...

PMC10443665

CCRF-CEM/MTX subline is the CCRF-CEM cells exposed to MTX 0.1 μM (MTX IC50) for 48 h. It should be noted that the IC50 of MTX was determined using different concentrations of it on CCRF-CEM cells through MTT assay (Fig. 1).

[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11467964

As shown in the waterfall map, 38 of 238 (15.97%) patients had mutations in these genes (Supporting Information S1: Figure S1), among which the top five mutated genes with their mutation frequencies were ACAN (3%), COL4A1 (2%), COL6A3 (2%), FBN2 (2%), and TNC (2%).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9596868

p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001; ****p ≤ 0.0001 represent significant changes.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Methods: We investigated the effect of small molecule inhibitor of TP53 mutation (APR-246) in combination with decitabine on the proliferation of MDS/AML cells (SKM-1, NB4 and KASUMI-1) which carries the recurrent homozygous TP53 mutation p.R248Q (TP53 ).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9261184

To ensure consistent FTIR performance throughput the testing period, the FTIR system was calibrated with reference gases once per day.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "ensure", "c...

PMC11473750

Positive (amplified) and negative (non-amplified) controls were included in each FISH run.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Positive", "(", "amplified", ")", "and", "negative", ...

PMC10723784

Therefore, it may be suggested that in ovarian cancer cannabinoids also induce cellular processes involving ROS signaling, which may be due to an impaired mitochondrial function.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11448304

In recent years, an increasing number of studies have focused on cancer lysine acetylation, such as esophageal squamous cell carcinoma , lung adenocarcinoma , gastric cancer and pancreatic cancer .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11754784

j Simulated reaction rate of different layers with or without considering the “diffusion trap” theory.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "j", "Simulated", "reaction", "rate", "of", ...

PMC8540692

CCM and NaBu are natural compounds with anticancer effects and minimal toxicity.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CCM", "and", "NaBu", "are", "natural", "compounds", "with", "anticancer", "effec...

PMC11106977

Hao et al. provided evidence that the expression levels of Notch signaling-activated genes, Rbpj and Hes1, were significantly induced in wild-type (Eogt) CD4 T cells but not in Eogt knockout (Eogt) counterparts.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Intravenous carfilzomib was given in a dose of 20 mg/m in cycle 1 day 1, and thereafter 56 mg/m (DL1-4) and 70 mg/m (DL5) on day 8, 15, and in all subsequent cycles and doses.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11277157

There are 76 antioxidant activity annotated genes (GO: 0016209; Supplementary Figure S1).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "are", "76", "antioxidant", "activity", "annot...

PMC10470467

And, according to calibration plots, we found that the mortality estimated by the nomogram was close to the actual mortality (Figure 9D), confirming the nomogram’s excellent accuracy.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11509224

Notably, the genera Spongia, Agelas, and Acanthella reported the highest number of diterpenes, with counts of 62, 33, and 17, respectively, accounting for 27%, 14%, and 7% of the total reported molecules, respectively.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Aims: To report the preliminary safety, tolerability, and initial antitumor efficacy of CB-010.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "To", "report", "the", "preliminary", ...

PMC11351758

Another research group reported that when catalase removed free radicals from the mitochondria, a 10% increment in the lifespan of the mouse was recorded, and they projected that similar results would be achieved in humans; however, there are currently no clinical trials to support this claim .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11422497

We have underscored its significant upregulation and unveiled its oncogenic function in GISTs, where it acts by sequestering miR-494-3p, thereby activating the KIT/JAK/STAT pathway.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11665584

Both ALDH3A1 and Aldh1a3 facilitate the critical step of converting retinal to bioactive RA within cells (63).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Both", "ALDH3A1", "and", "Aldh1a3...

PMC11514418

A total of 97 patients were included in the retrospective study.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "total", "of", "97", "patients", "were", "included", "in", "the", "retrospective"...

PMC11594806

Additionally, ALMB-0168 increases cytotoxic lymphocyte levels (CD3/CD8+ T cells) and helper T-cell levels (CD3/CD4+), improves survival rates, and reduces tumor metastasis .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC3019555

In contrast, only background fluorescence was observed upon coincubation with a sense DNA ODN (Fig. 3 A).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "contrast", ",", ...

PMC11576293

For C18H16ClN2OS (M + H) 343.06664; found 343.06726.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "C18H16ClN2OS", "(", "M", "+", "H", ")", "343.06664", ";", "found", "343....

PMC9429973

The median time from auto-HCT to VOD/SOS diagnosis was 14.0 (range: 0, 185) days.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "median", "time", "from", "auto-...

PMC9351137

In telophase, all the tested CRS were found at the midbody.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "telophase", ",", "all", "the", "tested", "CRS", "were", "found", "at...

PMC6461034

The other cell lines were cultured in RPMI 1640 containing 2 mM L‐glutamine and supplemented with 10% fetal bovine serum (K562 as a suspension culture).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", ...

PMC11585994

Each group received the corresponding nanoparticle formulation via intravenous injection through the tail vein.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "group", "received", "the", "corresponding", "nanoparticle", "f...

PMC11790971

The error bars represent the standard deviations of balanced accuracies at each iteration of RFE.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "error", "bars", "represent", "the", "standard", "dev...

PMC9429973

On the etiological assessment, protein electrophoresis objectified a monoclonal peak with the presence of an immunoglobulin G kappa at immunofixation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "On", "the", "etio...

PMC6835428

PARP mediates base excision repair of single-strand breaks to resolve spontaneous DNA damage .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PARP", "mediates", "base", "excision", "repair", "of", "single-strand", "br...

PMC11489175

A role for deubiquitinases (DUBs) is starting to emerge in ovarian cancer.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "role", "for", "deubiquitinases", "(", "DUBs", ")", "is", ...

PMC11525028

AG-401: 2.5 mg/kg daily, i.p.) (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "AG-401", ":", "2.5", "mg/kg", "daily", ",", "i.p", ".", ")", "(" ] } ]

PMC9436459

A., Artocarpus; B., Brosimopsis; B.*, Brosimum; C., Chlorophora; D., Dorstenia; M., Morus; S., Sorocea.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Animals were transfused when Hb dropped ≤5,5 g/dL. Results: Eight weeks after FLT, BM Tfr2 deletion improved anemia of Hbb mice with a gene-dosage effect, increasing RBC count and Hb levels and reducing the percentage of circulating reticulocytes.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

The most commonly reported adverse events (AEs) of any grade were nausea (6/31,19.4%), elevated liver transaminases (4/31,12.9%), and headache (3/31,9.7%); no severe AEs had been reported until the cutoff date.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9884169

Meanwhile, GEPIA database analysis showed that the long-term survival of bladder cancer patients with high expression of MCT4 was significantly lower than that of bladder cancer patients with low expression of MCT4, which suggested that MCT4 may be a potential target for bladder cancer therapy.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8557138

Freedman et al. demonstrated the construction of genetically modified kidney organoids to study genetic kidney disease (Freedman et al. 2015).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Freedman", "...

PMC11714165

The standard IκB kinase (IKK) complex activates the NF‐κB pathway, with NF‐κB essential modulator (NEMO) acting as a regulatory subunit by interacting with both IKKα and IKKβ.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10798140

The novel quinoline derivative (compound 91b1) developed by Yuan Zhou demonstrated antitumor efficacy in nude mice via downregulation of lumican.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "novel...

PMC10218459

A corresponding second plate was treated in parallel to normalize the absorption values to cell numbers.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "corresponding", "second", "plate", "was", "treate...

PMC11243198

In our study, we aimed to identify novel and potent GLI antagonists with potentially improved physicochemical properties.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "our", "study", ",", "we", ...

PMC11537649

The experimental procedure was conducted following the protocol of the manuscript of the EZ-Magna RIP kit (#17–295, Millipore, Billerica, MA).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC9429973

Overall, median CS dose decreased over time in the RUX and BAT arms and was similar between groups.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overall", ",", "median", "CS", ...

PMC10854447

Antiproliferative activity of compounds 7a–o and Erlotinib.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Antiproliferative", "activity", "of", "compounds", "7a", "–", "o", "and", "Erlotinib", "." ] } ]

PMC7823217

Along with malignant cells, stromal cells of breast cancer also greatly influence the progression of tumor by altering the cells phenotypes, secreting signaling molecules and reorganizing themselves to support tumor invasion (Fig. 3-A).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11488203

A potential clinical use of MSC-derived EVs/exosomes is attractive as a cell-free system due to a reasonable biocompatibility and a reduced immunogenicity as compared to a cellular system.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11711127

The main APC for T cells are DCs, which exist in different states including operationally defined tolDC.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "main", "APC", "for", "T", ...

PMC11746942

A Western blot analysis of S1PR3 expression in HaCaT cells treated with increasing concentrations of IL-6 (top) or IL-22 (bottom).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "token...

PMC10747160

Contrary to expectations, we observed a similar phenomenon as described for WT-Grft: GLG-3A consistently appeared to enhance Raji DC-SIGN+ SARS-CoV-2 pseudoviral infectivity by at least 1 order of magnitude (Figure 4D).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", ...

PMC11766309

In addition, the independent prognostic value of YKT6 was analyzed via a K‒M plot.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "the", "independent", "prognostic", "...

PMC11286266

Treatment with DTT for 1 hr (4 mM) was used to induce ATF6α processing.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Treatment", "with", "DTT", "for", "1", "hr", "("...

PMC7185206

Our findings further support that pre-treatment tumor expression of PD-L1 by immunohistochemistry is insufficient to determine whether a patient may benefit from a PD-(L)1 inhibitor.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC10993311

Descriptive statistics were used for data analysis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Descriptive", "statistics", "were", "used", "for", "data", "analysis", "." ] } ]

PMC9429973

AZA was administered every 21 days (d) for 4 cycles (cy), with the following schedule: 55 mg/m for 5 d, 55 mg/m for 7 d, 75 mg/m for 5 d, 75 mg/m for 7 d, respectively; prednisone 1 mg/m was associated to each cycle.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8567602

To test the tumorigenic potential of Smarcb1 loss alone in mesenchyme, we injected TATCre protein into the paws of mice homozygous for a conditional disruption allele of Smarcb1 (5).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10125312

A suspension of 8 × 10 cells in 20 μL on a 96-well plate (Round bottom, Corning 3879, Corning Inc.) was irradiated from the top with a 3 mm diameter cw collimated laser beam from a Ti:sapphire laser (LU0808D 180 diode laser, LuOcean Mini, Lumics GmbH) adjusted to a wavelength of 808 nm.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11400680

We intentionally used this idea with the aim of capturing all potential prompts for cells and nuclei, thereby reducing the probability of missed detections.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC11609529

We show that the YM fusion forms nuclear condensates, interacts with the TEAD transcription factors, and activates YAP1/TEAD-mediated transcription.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "show", "tha...

PMC11787381

Some of the methods studied include enhancing NE signaling in the brain through the use of β2-AR agonists, among which terbutaline has been found to prevent the Aβ mediated inhibition of Long-Term Potentiation (LTP).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11351758

Severely depleted or peroxidized CL can enhance the opening of the mPTP, which could meet the minimum threshold for Ca and thus further enhance and potentiate mCa toxicity in the opening of the mPTP.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11718109

The N2 medium is comprised of Neurobasal Plus media (Thermo Fisher Scientific), 2% B27 supplement without vitamin A (Thermo Fisher Scientific), 1% N2 supplement, 1% glutaMAX and 0.2% penicillin-streptomycin.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

There were 365 (6.1%) VTE, among them 137 (2.3%) DVT and 262 (4.4%) PE.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11391695

A concurrent and substantial decrease in both the quantity and mass of tumors was identified (Fig. 7D, E).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "concurrent", ...

PMC11626627

In our previous study, we found that overexpression of circATP2B1 inhibited the invasion of ccRCC.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "our", "previous", "study", ",", "we", "fou...

PMC11594074

Imaging was carried out using an AF7000 Widefield Fluorescence Microscope (Leica, Wetzlar, Germany) (40× magnification) at the green channel (488/510 nm) and DAPI (358/461 nm) in order to determine KI-67 localization and expression.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10565698

Western blotting results confirmed the elevation in E-cadherin expression and the decrease in N-cadherin and vimentin expression after the dysregulation of circUSP10 expression (Fig. 3I).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9596868

Table 1A: Combination index for quercetin with chemotherapeutic drugs/compounds in cancer cell lines.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Table", "1A", ":", "Combination", "index", "for", "quercetin", "...

PMC11243198

Purmorphamine was purchased from Cayman Chemical (Ann Arbor, MI, USA).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Purmorphamine", "was", "purchased", "from", "Cayman", "Chemical", "(",...

PMC9429973

In contrast, the antiviral foscarnet was not associated with mutations in HSCs.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "contrast", ",", "the", "antiviral", "foscarnet", "was", "not", ...

PMC11471157

Medaka was the only fish species used, and it is necessary to verify whether similar effects are observed in other small fish species to confirm the advantages of this microcarrier for cell culture.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Methods: Pts were randomized 1:1 to receive up to 6 cycles of A+AVD (n=664) or ABVD (n=670) on day 1 and 15, every 28 days.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11679892

A similar trend was observed during the 48 h incubation period, and it was determined that the cytotoxic effect of P. sidoides continued stably as time progressed.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11506827

The gintonin-enriched Panax ginseng extract fraction (GEF) has diverse pharmacological benefits.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "gintonin-enriched", "Panax", "ginseng", "extract", "fraction", "(", ...

PMC11783017

Benefiting from the high ROS levels in the tumor microenvironment, ROS-responsive hydrogel-based nanomedicines offer an alternative approach for local drug delivery, achieving precise and sustained drug release via intratumoral injection.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11354225

Cells were seeded in T25 flasks.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "seeded", "in", "T25", "flasks", "." ] } ]

PMC9917080

The effect of SeNPs and SeSo increased after 48 h of incubation with cells, which correlated with the depletion of the Ca pool of the endoplasmic reticulum.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11615218

With comprehensive insight into the biological processes underlying successful CAR-T cell therapy, we will further refine the applications of these novel therapeutic modalities, and enhance their efficacy and safety for patients.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10631132

After EB induction, cells were fixed with 4% paraformaldehyde (PFA) and blocked with PBS containing 10% normal goat serum (Abcam, Cambridge, UK), 0.3% Triton X-100 (Sigma-Aldrich, St. Louis, MO, USA), and 1% bovine serum albumin (BSA) (Sigma-Aldrich, St. Louis, MO, USA).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11723210

By comparing with the results from digital holography, we verified the accuracy of the QPI results, especially for samples with large phase values.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC3765139

The aim of the study was to identify CSC markers potentially allowing the functional characterization of specific cell subsets from clinical specimens, which have been identified in different types of tumors, including melanoma .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11798926

p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC7759933

Long-term cultivation of HepG2 cells in 3D conformation led to the enhancement of the expression of liver-specific markers, as shown for alpha-fetoprotein (AFP) and albumin (ALB) compared to monolayer culture (Figure 4).

[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11298021

In contrast, transfection of Jurkat cells with miR-3143 or miR-3182 and subsequent treatment with rapamycin resulted in a significant decrease in the mRNA expression of PI3K, AKT, mTOR, and S6KB1 genes.

[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8427838

D Whole cell lysates (WCL) derived from HEK-293 cells expressing empty vector (EV), GFP-tagged moesin (MSN-GFP) or GFP-tagged ezrin were incubated with GST, GST-TMIGD1 or GST-4A-TMIGD1 followed by western blot analysis using an anti-GFP antibody.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...