Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
 Community
1
PMCID
string
Sentences
string
ner
list
PMC9429973
Factor VIII/IX levels (IRR 0.88, 95%CI 0.80-0.96, p=0.005) and BMI (IRR 0.68, 95%CI 0.55-0.82) were also independently associated with the frequency of joint and muscle bleeding.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11489351
A, representative confocal images of MCF10A cells treated for 24 h with EIPA to lower pHi or NH4Cl to raise pHi.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", ...
PMC9429973
The initial symptomatology was polymorphic: cutaneous-mucosal involvement, cardiac symptomatology and neurological symptomatology were noted in 50%, 30% and 25% of cases respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11628904
Other studies have targeted burn wound conversion to improve burn wound healing, primarily by reducing inflammation and apoptotic cell death.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Other", "studies", ...
PMC9024365
Interestingly, these effects are potentiated when expressed with TARP-γ8 (Matt et al., 2018), indicating that SD4 may function in AMPAR complexes containing TARP-γ8.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10454535
A clinical trial comparing BTZ/dexamethasone treatment to reduced dose BTZ/thalidomide and dexamethasone treatment showed the reduced dose BTZ treatment to have a greater overall complete response plus very good response in newly diagnosed MM patients, along with decreased peripheral neuropathy severity .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11740399
The resulting suspension was put in an ice bath and sonicated for 2 min to produce 3025@L. Cell membrane vesicles were harvested and extracted from T24 cells, as reported by Zhang et al. ‘s method .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", ...
PMC9429973
To prospectively study the propensity of patients to lose their monosomy 7 clone, EWOG-MDS elected to delay immediate hematopoietic stem cell transplantation (HSCT) in children <5 years of age diagnosed of refractory cytopenia (RCC) with germline SAMD9/9L mutation and monosomy 7.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11543853
A selected actin microfilament is indicated by a cyan arrowhead.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "selected", "actin", "microfilament", "is", "indicated", "by", "a", "cyan", "arrowhead", ...
PMC11509224
−)-Agelasine D was more cytotoxic to Hep3B cells than (−)-agelamide D, with their GI50 values being 9.9 and 12.0 µM, respectively .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11641630
These findings align with those of Garden et al. , who observed reduced migration in M. bovis BCG-treated EJ human transitional carcinoma cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11686380
These results strongly demonstrate critical roles of GAP43 in brain development and the etiology of neurodevelopmental disorders.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "results", "strongly", "demonstrate", "cr...
PMC11629143
Concentration and quality of RNA were measured on a Nanodrop One (Thermo Fisher Scientific).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Concentration", "and", "quality", "of", "RNA", "were",...
PMC10777969
Thiadiazoles, a subfamily of azoles, are used as bioisosteres of thiazole, oxazole, oxadiazole, and benzene for the development of analogs with biological properties comparable to those of their precursors.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10705095
Recent studies have detected HBQ1 expression in non-erythroid cells, such as alveolar epithelial cells .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Recent", "studies", "have", "detected", "HBQ1", "expression", ...
PMC8978939
Using VarSome to follow the ACMG guidelines for classification of new variants, they are classified as likely pathogenic (P138R) and pathogenic (L163R).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10454535
Interactions between BMSCs, osteoblasts, osteoclasts, endothelial cells, and MM cells alter the bone marrow microenvironment, largely contributing to drug resistance exhibited by MM cells in vivo .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9412887
In recent years, nanomedicines, a new and effective strategy for surmounting cancer drug resistance, have attracted increasing attention.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "recent", "y...
PMC9424261
The results shown that after the same drug treatment, the size of HERPUD1-sg1 xenografts is larger than that of wild-type, indicating that ferroptosis is reduced after knockout of HERPUD1, and the inhibitory effect of drugs on xenografts is weakened (Fig. 6A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10297204
Achieving a wide margin, covered with the surrounding healthy tissue, might reduce the local recurrence rate and result in improving overall patient survival .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11774112
MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) was obtained from HXBIO (Hangzhou, China).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MTT", "(", "3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium", "bromide", ")",...
PMC9429973
N. Bouayed Abdelmoula, B. Abdelmoula, A. Sbai, M. Ben ayed, S. Aloulou Genomics of Signalopathies at the service of Medicine, Medical University of Sfax, Sfax, Tunisia Background: The Philadelphia chromosome (Ph) is detected in 10–20% of adult patients with B-cell acute lymphoblastic leukemia (B-ALL).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
An IPTW-weighted Cox proportional hazards model, adjusted for variables that remained unbalanced after weighting, was used to compare OS between treatment groups.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10197932
RBC were washed in PBS + 5% BSA then resuspended in same buffer and analyzed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RBC", "were", "washed", "in", "PBS", "+", "5", ...
PMC11648299
No data on exposure to ultraviolet light was available and the association observed might be inflated due to surveillance bias (i.e., more frequent visits to a dermatologist among patients with DD).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11723210
In contrast, achieving precise reconstruction of large phase samples using a miniaturized, lens-free microscope with an LED light source would offer significant advantages in terms of both simplicity and cost effectiveness.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11509278
The IC50 values of propolis from Thailand for A549 cells were 106 ± 0.004 µg/mL, 199 ± 0.009 µg/mL, and 87 ± 0.012 µg/mL, respectively, and their IC50 values for HeLa cells were 81 ± 0.006 µg/mL, 116 ± 0.023 µg/mL, and 54 ± 0.005 µg/mL, respectively .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9784246
Even though there is currently no evidence to support the anti-L. major from in vivo animal models, the LC-MS/MS examination clearly showed the existence of several metabolites with well-established in vivo antiprotozoal action against various Leishmania spp.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8973725
Given that ZNF677 is a putative transcription factor, we speculate that it may bind to downstream target genes to regulate the PI3K/AKT signaling pathway.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10969097
Hence, there is an imperative need to find strategies capable of reverting MDR-related chemoresistance and, when possible, lowering the chemotherapy basal toxicity.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11763111
Beads were counted to calculate the number of remaining CAR-T cells and GFP-positive tumor cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Beads", "were", "counted", "to", "calculate", "the", "numbe...
PMC11437637
Add 450 µl of hemolytic agent for flow cytometer to the tube.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Add", "450", "µl", "of", "hemolytic", "agent", "for", "flow", "cytometer", ...
PMC9429973
In both arms, pain decreased after treatment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "both", "arms", ",", "pain", "decreased", "after", "treatment", "." ] } ]
PMC11783017
Ⅰ: Control, Ⅱ: PGP, Ⅲ: Mn@PGP, Ⅳ: Cis/Mn@PGP, Ⅴ: Mn/NH@PGP, Ⅵ: Cis/Mn/NH@PGP.Fig.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ⅰ", ...
PMC5839394
Both ethanol precipitates were dried out under vacuum and grinded in a mortar.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Both", "ethanol", "precipitates", "were", "dried", "out", "under", "vacuum"...
PMC11607764
qRT-PCR validation of PTBP1 expression within cell lines and mice after modeling. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "qRT-PCR", "validation", "of", "PTBP1", "expression", "within", "cell", "lin...
PMC9844987
E–F) Average nucleosome fuzzy score across all 7 LCLs, split by variability quartiles (E) and minimum correlation between contained decomposed promoter pairs (high Pearson’s correlation >0.39: solid colors, low Pearson’s correlation ≤ 0.39: faded colors) (F). (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5833712
Posttranslational acetylation of ERα was recently reported to play an important role for its activity as a ligand-activated transcription factor and for its stability.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11173119
IPSCs were placed on a Petri dish (D60 mm) coated with mitotically inactivated MEFs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "IPSCs", "were", "placed", "on", "a", "Petri", "d...
PMC11365983
Next membranes were incubated with relevant primary antibodies, followed by IRDye-conjugated secondary antibodies.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Next", "membranes", "were", "incubated", "with", "relevant", "primary"...
PMC10094712
The results were expressed as 2, where ∆(∆Ct) is the difference between the ∆Ct values between the gene under study and a housekeeping gene.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9473868
Activated FLSs are resistant to cell apoptosis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Activated", "FLSs", "are", "resistant", "to", "cell", "apoptosis", "." ] } ]
PMC10729469
212–12, Peprotech, Cranbury, NJ) in complete RPMI-1640 media supplemented with 10% fetal bovine serum (FBS), 2 mM L-glutamine, 25 mM HEPES, 1 mM sodium pyruvate, 1 × nonessential amino acids, 55 nM 2-mercaptoethanol, 100 U/mL penicillin, and 100 μg streptomycin (complete RPMI-1640).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11773391
Malignant melanoma results from the malignant transformation of melanocytes, which are of neural crest origin .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Malignant", "melanoma", "results", "from", "the", "mal...
PMC11773391
Lipofectamine 3000 (Thermo Fisher Scientific Inc.) was utilised to perform transfection with 5.0 μg of the pcDNA3.1(+)‐MGMT vector or 5.0 μg of the pcDNA3.1(+) empty vector (as a negative control) according to the manufacturer's instructions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8345486
The modification at the C8 position of the nucleoside (compound 19) was less effective on cell viability than the unmodified cage, and significant differences were found only for A2780cis (p < 0.01) and OVCAR-3 cells (p < 0.05).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11129910
Both exons of the H-RAS gene, 1 and 2, are analyzed by bidirectional Sanger sequencing.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Both", "exons", "of", "the", "H-RAS", "gene...
PMC11476264
Research shows that ZEB1 can induce EMT in breast cancer , osteosarcoma , lung cancer , melanoma , and other epithelioma, leading to tumor metastasis and promoting drug resistance.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10380508
Patients with incomplete clinical information were excluded from the study.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "with", "incomplete", "clinical", "information", "were", "excluded", "from", "the", "...
PMC6468656
According to the results of a pancreatic adenocarcinoma study, ghrelin promoted cell migration via the activation of GHSR/PI3K/Akt signaling pathway, and the phenotype was inhibited by the addition of ghrelin receptor antagonist .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
A. Bazinet, T. Kadia, N. Short, G. Borthakur, S. Wang, S. Loghavi, J. Jorgensen, K. Patel, C. DiNardo, N. Daver, Y. Alvarado, F. Haddad, S. Pierce, M. Andreeff, E. Jabbour, M. Konopleva, H. Kantarjian, F. Ravandi Leukemia; Hematopathology, University of Texas MD Anderson Cancer Center, Houston, United States of America Background: Modern therapy for acute myeloid leukemia (AML) can consist of either intensive or low-intensity regimens selected based on patient (pt) age/comorbidities.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11261875
Jun Arima: Writing – review & editing.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Jun", "Arima", ":", "Writing", "–", "review", "&", "editing", "." ] } ]
PMC9479186
Tumor biological function of NDUFC1. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tumor", "biological", "function", "of", "NDUFC1", ".", "(" ] } ]
PMC9429973
This result compared well with the previous finding of 28 days reported in an historical group of HM patients not treated with nMoAbs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", ...
PMC11767725
This activation promotes further cytokine release and oxidative stress, creating a feedback loop between systemic lipid imbalances and local skin inflammation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "acti...
PMC7229095
Additionally, FDA points out recently that cloning should be performed after an adaptation of cells to serum-free or suspension culture conditions, and an additional cloning is required when post-cloned cells are adapted to new conditions (Welch and Arden 2019).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11634794
The correlation between LAMP1 and immune cell infiltration levels, as well as the association between immune cell infiltration and different expression groups of LAMP1, were investigated using Wilcoxon rank sum test and Pearson correlation analysis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11725127
These data suggest that GA can induce the proteasomal degradation of KRAS, which in turn impairs the downstream signal transduction in MM cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11411131
The Luc-391Sec and Krab-Sec/Luc sensor vector designed for detect MeHg-dependent deficiency of Sec incorporation (Figs. 2 and 6).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "Luc-391Sec", "and", ...
PMC9813422
KSHV was discovered as the causative agent of AIDS-associated Kaposi sarcoma (9).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "KSHV", "was", "discovered", "as", "the", "causative", "agent", "...
PMC9429973
Aims: The national survey MPN-QoL-2020 was aimed to evaluate QoL and symptom burden in patients with MPN, as well as to examine the perceptions of patients and physicians about the impact of MPN and its treatment in a real world setting in Russia.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10607604
Conversely, in the new series, all patients received the carboplatin/paclitaxel combination.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Conversely", ",", "in", "the", "new", "series", ",", "all", "patients...
PMC9429973
This response is an emergent property of the abundance of the signalling network’s components along with the binding affinities, regulatory interactions and kinetic rates.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973
Treatment with HU for a year with fixed dose of 20 mg/kg/day was associated with lower stroke recurrence rates if started within 2 months of initial stroke.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11472639
Pulmonary oxygen uptake (), carbon dioxide production (), and ventilatory equivalents of O2 and CO2 () data were interpolated to 15-s averages.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11739504
Scale bar: 2 μm (e) Graphs showed fluorescence intensity of IFT25 and IFT52 under serum starvation 6 h, 24 h in stable Kat2b KO NIH3Te and control NIH3T3. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9503669
Work with these compounds is consistent with earlier studies implicating Nef-mediated Hck activation as an early step in the MHC-I downregulation pathway described above.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11756514
The GFP-positive events were gated as bacteria; see the gating strategy in Supplementary Figure S3B .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "GFP-positive", "events", "were", "gated", "as",...
PMC9429973
Protein complexes and expression of apoptosis regulators were analyzed by immunoprecipitation and immunoblotting.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Protein", "complexes", "and", "expression", "of", "apoptosis", "regulators", ...
PMC9429973
Pts received a median of 1 cycle (range, 1-4).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Pts", "received", "a", "median", "of", "1", "cycle", "(", ...
PMC11574029
Images were captured and analyzed using an Olympus fluorescence microscope and AxioVision image analysis software.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Images", "were", "captured", "and", "analyzed", "using", "a...
PMC4695073
The blots were probed with anti-XPA (1:1,000) or anti-GAPDH (1:2,000) antibody, followed by reaction with HRP-conjugated secondary antibody.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC5417661
Rj:NMRI-Foxn1nu/Foxn1nu female mice (Janvier Laboratories, St Berthevin Cedex, France) were used in the maximal tolerated dose and xenograft assays, and C57Bl/6 male mice (Taconic Biosciences Inc., Ejby, Denmark) were used in the pharmacokinetic study.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11591030
Specifically, compared to the control group, supplementation with 150–250 μg/mL AOP mitigated the reduction in Nrf2 and SOD gene expression and decreased the Keap1 overexpression, with protective effects comparable to those observed with VA (p < 0.05).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Among the 9 patients who were alive 6 were in complete hematological response and 3 were in partial response after 6 cycles of therapy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11087055
Embryos were then incubated in blocking reagent [1% bovine serum albumin (BSA) and 0.1% triton in PBS] for 1 hr at RT.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10048572
In 92 clones, EMAST was detected for one marker, in 12 clones for two markers, in one clone four mutant loci were observed, in five clones EMAST was detected in five loci, and in three of them the patterns of aberrant loci were identical (Jurkat-O1 379, Jurkat-O1 380, Jurkat-O1 381, Table S3).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7039683
Raw and processed sequencing data for this H3K27Ac ChIP-seq were deposited in GEO repository (GSE139809).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Raw", "and", "processed", "sequencing", "data", ...
PMC10965315
However, when N‐acetyl cysteine (NAC) was administered along with harmaline, there was a notable inhibition of harmaline‐induced ROS production.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However...
PMC9429973
Q. Han, C. Song, Z. Ge Department of Hematology, Zhongda Hospital，School of Medicine, Southeast University, Institute of Hematology Southeast University, Nanjing, China; Hershey Medical Center, Pennsylvania State University, Hershey; Division of Hematology, The Ohio State University Wexner Medical Center, the James Cancer Hospital, Columbus, United States of America Background: T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignance with limit treatment choices and extremely poor prognosis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11782508
The total protein concentration in the supernatant was quantified using the Bradford method by measuring absorbance at 595 nm.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "total", "protein", "concen...
PMC11794847
For tail vein implantation group, at least three mice for each HVEM KO group and wild type group were euthanized at Day 10 and Day 20 after implantation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9964635
The anti-liver carcinoma effects of all of the derivatives against a HepG2 cell line were investigated.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ "The", "anti-liver", "carcinoma", "effects", "of", ...
PMC11725127
The precipitates were separated by SDS-PAGE and detected by western blotting with HRP-streptavidin and anti-USP2 antibody, respectively. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "precipitates", "were", "se...
PMC11707577
The effect of phage‐mediated PDT was evaluated by looking for possible changes in the spheroid morphology, as well as by determining the cell viability after irradiation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11693599
Both pOC-derived EVs were small, with a mode size less than 100 nm, and the size of pOC #1-derived EVs (33.3 ± 12.4 nm) was more heterogeneous than the size of pOC #2-derived EVs (61.0 ± 2.9 nm, Fig. 4B).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11519567
Scale bars, 5 μm.
[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bars", ",", "5", "μm", "." ] } ]
PMC11718817
Validation of NLRP3-related effects on T cell motility and effector function is difficult to achieve.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Validation", "of", "NLRP3-related", "effects", "on", "T", "...
PMC10907726
Furthermore, it has been reported that DATS has the ability to reduce the risk of gastrointestinal cancers , reverse chemotherapy resistance , and enhance anti-cancer activity when combined with biomaterials .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
However, those studies highlighted the importance of TReg expansion and its prognostic impact in high risk.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "those", "studies", "highlighted",...
PMC11763126
After thawing, the samples were centrifuged at 12,000 g for 20 min, and the supernatant was collected and mixed with lysis buffer at a ratio of 1:7.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11348300
Illustration depicting the mechanism of PRESTO in a subdermal tumor.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Illustration", "depicting", "the", "mechanism", "of", "PRESTO", "in", "a", "subdermal", "tumor",...
PMC11727907
Growth factor signaling may affect the catalytic activity of PKM2, inducing its nuclear translocation, as we previously demonstrated in treating a human lung adenocarcinoma cell line with insulin-like growth factor 1 (IGF-1) .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLin...
PMC11806182
Through these networks, several key genes were identified.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Through", "these", "networks", ",", "several", "key", "genes", "were", "identified", "." ] } ]
PMC11489351
After identifying the subset of transcripts that are differentially regulated at high and low pHi, we biochemically validated a collection of pH-dependent hits that clustered in signaling and metabolic pathways.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
In CML, OR21 plus TKIs (imatinib, dasatinib, ponatinib) synergistically inhibited cell growth, increased apoptosis in CML cell lines as similar to AZA and DAC, and significantly suppressed the colony-forming capacity of bone marrow CD34 stem/progenitor cells in CML patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Aims: The aims of this study were to distinguish RUX-treated pts at higher risk of COVID-19 and to assess prognostic factors for OS.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973
All cases showed PD-L1 expression; differences in the HSM mean between groups were observed: AGP: 266, GP-G: 123 and GP-P: 60 (p<0.01).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Seven pts (16.7%), of whom 2 had high-risk disease, attained CR at a median of 6.0m. ORR for pts receiving vs not receiving R were 84.2% and 66.7% respectively (p=0.1904).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9960565
The ζ-potential measurements were performed using a Malvern, Zetasizer Nano ZS equipment with a He–Ne laser and 633 nm wavelength at 25 °C with disposable folded capillary and cuvettes (DTS1060C and ZEN0040, Malvern, respectively).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...