OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC11721277	A group of four mice was used per data point.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "group", "of", "four", "mice", "was", "used", "per", "data", "point", "." ] } ]
PMC11756514	MBL binding was detected by flow cytometry using streptavidin-BV421 to detect bound biotinylated MBL.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MBL", "binding", "was", "detected", "by", "flow", "cytometry", "...
PMC10926885	However, studies examining the connection between NDE1 and cancer is still very rare.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "studies", "examining", "the", "connection", "between",...
PMC11122631	for 429.2248).	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "for", "429.2248", ")", "." ] } ]
PMC11267036	Cells without any treatments served as the control cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "without", "any", "treatments", "served", "as", "the", "control", "cells", "." ] } ]
PMC9581083	Antiviral drugs must enter infected cells and work, often resulting in a number of side effects (Wang and Yang, 2020; Wang and Yang, 2021b; Wang and Yang, 2022).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11377827	HeLa HRE-GFP reporter cells treated with 14-3-3 pan siRNA, 14-3-3 epsilon sgRNA or 14-3-3 zeta sgRNA were analysed by flow cytometry.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11727062	It has been found that mononosides significantly inhibit the proliferation of A375 cells in a dose-dependent manner.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "has", "been", "found", "that", ...
PMC9429973	TSAT escalation stopping rules were not met in any subject, but in the 14mg group, two subjects had a majority of individual TSAT values >40% through Day 15, as compared to none in the 7mg group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11594641	Contrary to RAB27A KO A375 sEVs, the TSG101 level in dKO sEVs was not elevated compared to wild-type sEVs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Contrary", "to", "RAB27A", ...
PMC9429973	Patients also reported increase in PV-related symptoms (i.e., increased fatigue and worsening concentration).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "also", "reported", "increase", "in", "PV-r...
PMC9429973	We enrolled 230 AML pts with a median age of 75 years (range 25-94); 157 pts (68%) had >2 relevant comorbidities.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	This abstract is an encore from the Society of Hematologic Oncology 2021 Annual Meeting.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "abstract", "is", "an", "encore", "from", "the", "Society...
PMC11609529	In this study, we utilize ovarian cancer ES-2 cells as a YM-positive cancer cell model to investigate the mechanisms and functional roles of the endogenous YM fusion in cancer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9351137	Once chromosome segregation is complete, the actomyosin contractile ring is assembled at the cleavage furrow and drives the constriction of the plasma membrane where abscission, the final stage of cytokinesis, will occur.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11707577	In particular, bacteria were grown in LB liquid supplemented with Kanamycin (25 mg L), Ampicillin (100 mg L), and 0.4 mm IPTG for 24 h. Next, the bacterial culture was centrifuged for 20 min at 12 000 g and the obtained supernatant was supplemented with PEG 8000 (4% w/v) and NaCl (3% w/v).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6267596	A profile plot showed protein expression patterns that identified 34 and 79 proteins as up-regulated that follow the same pattern, respectively, and 35 and 44 proteins follow the same pattern as down-regulated, respectively (Figure 4c and Figure 4h).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9592219	Then, the siRNA and Lipofectamine were incorporated, carefully mixed, and incubated at 14°C for 20 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "the"...
PMC11718031	Before the basal media screening fed-batch experiments, cells were passaged twice in the 100% basal medium.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Before", "the", "basal", "media", "scr...
PMC11201989	Considering the role of PD-L1 in regulating immune synapse formation, and the striking similarities between immune synapse and the primary cilia, it is possible that PD-L1 might have a role in regulating primary cilia formation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9822769	Interestingly enough, the peak potential (Ep) trend is opposite to that of kinetics (k, see the t½ values in Table 1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8973085	White solid [A] (89%); [B] (73%); mp: 205–207 °C (EtOH); IR (KBr, v, cm): 3434 (NH), 2222 (CN), 1705 (C=O), 1656 (C=O); H NMR (DMSO-d6): δ 2.25 (s, 3H, CH3), 2.32 (s, 3H, CH3), 4.95 (s, 2H, CH2), 7.09–8.14 (m, 13H, CH-Ar), 10.46 (bs, 1H, NH); C NMR (DMSO-d6): δ 21.31, 22.86, 39.73, 103.95, 115.45, 115.84, 115.97, 121.87, 121.91, 128.70, 128.74, 129.31, 129.53, 131.51, 133.99, 136.87, 139.89, 151.77, 158.29, 161.29, 164.12, 193.84; MS m/z (%): 495 [M] (65), 463 (5), 384 (100), 105 (55).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Binary logistic regression was used to develop a predictive scoring system.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Binary", "logistic", "regression", "was", "used", "to", "develop", "a", "predictive", ...
PMC11590870	As for amaranth hydrolysate, 1160 µg/mL led to a significant inhibition of ROS, keeping cells in the basal state .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "for", "amar...
PMC11730000	However, these differences were not significant compared with the DOX-treated group (Figure 7C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "these", "differences", "were", "not", ...
PMC11588085	In ovarian cancer, CD24 has been shown to be expressed in epithelial CSCs (62, 63).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "ovarian", "cancer", ",", ...
PMC9577200	According to our findings, the inhibition of chitosan carried out by the previous determination against BC was higher than PAO1 at all concentrations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC6617630	FISH was performed using standard FISH methodologies .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "FISH", "was", "performed", "using", "standard", "FISH", "methodologies", "." ] } ]
PMC11721295	Double- and single-positive cells were counted and specified quantifications were performed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Double-", "and", "single-positive", "cells", "were", "counted", "and", "specified", "quanti...
PMC11770130	The suppression of ceramides C20–C24 production in adipose tissue by depleting CerS2 downregulated food intake, but the local treatment of ceramides C20–C24 in vivo upregulated food intake.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11335267	Normally, Pomc/Cart neurons respond to leptin generated from the adipose tissue upon feeding , and as a consequence, they release αMSH to activate MC4R expressed in the paraventricular nucleus to promote satiety signals , to which co-released CART also contributes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4659567	C NMR (CDCl3, ppm): δ 149.9 (C6), 149.3 (C7a), 133.8 (C4), 132.2 (C2), 126.1 (C3a), 112.1 (C5), 103.4 (C14), 97.9 (C11), 83.7 (C13, C15), 81.6 (C12, C16), 30.6 (C17), 22.2 (C18, C19), 18.2 (C20).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11621493	Changes in DAG and MAG are consistent with the high MMAT activity of PLA2G4D.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Changes", "in", "DAG", "and", "MAG", "are", "consistent", "with"...
PMC9429973	Summary/Conclusion: Sd was able to induce an encouraging response with a manageable safety profile for a group of Chinese RRMM patients desperately needing treatment after failing CAR-T therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11708541	In order to create new aminopyridone derivatives and to check them for nootropic activity, the synthesis of compounds 61 based on amino-methyl—phenylpyridine was performed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11597291	Such conjugation processes are used for the loading of drugs and small molecules, genes, antibodies, and aptamers on GO nanomaterials .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Such", ...
PMC9429973	X.-H. Zhang, S. Chong, P. Zhao, R.-B. Huang, H. Zhou, J.-N. Zhang, Q.-S. Huang, H.-X. Fu, Q. Jiang, H. Jiang, J. Lu, X.-J. Huang Peking University People’s Hospital, Beijing; The First Affiliated Hospital of Nanchang University, NanChang; Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou; Peking University Cancer Hospital and Institute, Beijing, China Background: ITP is more likely to be persistent or chronic in adults, whereas it is a self-limiting disease in children.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8875242	The final concentration of DMSO was 0.1% in all experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "final", "concentration", "of", "DMSO", "was", "0.1", "%", "in", "all", "...
PMC11802855	At 7 weeks, three out of five mice in the CXCL7-OE group exhibited symptoms of long bone fractures.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "7", "weeks", ",", "th...
PMC11706491	Table showing the mean ± SD of all the growth parameters that can be measured with the cell cycle reporter strain.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Table", "showing", ...
PMC8711270	Current examples include the commercially available LV and AAV vector production workflow offered by Thermo Fisher Scientific, where their HEK293-derived Viral Production Cells (VPC) are used in the LV-MAX system and the upcoming VPC 2.0 used in their prototype AAV-MAX system.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9111184	Ezetimibe showed the highest permeability.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ezetimibe", "showed", "the", "highest", "permeability", "." ] } ]
PMC10914904	vtRNA 1-1, vtRNA 1-2, vtRNA 1-3 encode on locus 5q31.3, while vtRNA 2-1 is encoded on locus 5q31.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11718274	Imaging using TEM revealed a cubic shape and well dispersion of the ultra-sonicated Y2O3NPs in aqueous medium with a reduced mean particle’ size of 14.15 nm as depicted in Fig. 3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11468365	An attention mechanism is adapted to customize the shared features for two distinct target tasks.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", "attention", "mechanism", "is", "adapted", "to", "cust...
PMC11088135	Protein bands were visualized with ECL detection kit (Beyotime).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Protein", "bands", "were", "visualized", "with", "ECL", "detection", "kit", "(", "Bey...
PMC11449273	Plakoglobin suppression of nuclear β-catenin localization in the H1299-PG-p53-175 cells could explain its anti-tumorigenic effect in these cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Plakoglobin",...
PMC11594806	In a phase 2 trial for unresectable stage III non-small-cell lung cancer, adding oleclumab to durvalumab increased the objective response rate (ORR) from 17.9% to 30% and significantly extended PFS, with 12-month PFS rates rising from 33.9% to 62.6% .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Methods: A hematopathologist identifies a large B-cell lymphoma, and additional testing is ordered for further classification of the lymphoma (including Lymph3Cx analysis).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC8097906	All statistical tests on metabolite profiles have been conducted in R (www.r-project.org) using the respective functions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "statistical", "tests", "on", "m...
PMC9621239	To verify this speculation, the mRNA and protein levels of MYC in HCC cell lines stably expressing wild-type HBx, mutant HBx and lentiviral empty vector were analysed using quantitative PCR (qPCR) and western blot assay, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8382973	The rabbits were 8 to 9 weeks old and weighed between 1.790 and 2.424 kg.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "rabbits", "were", "8", "to", "9", "weeks", "ol...
PMC9268620	Conclusion: Therefore, we report that damnacanthal and nordamnacanthal exhibit anticancer properties by inducing apoptosis and necrosis in CEM-SS cells, and they have potential as a drug for the treatment of T-lymphoblastic leukemia.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Methods: Molecular analyses were performed either by direct Sanger sequencing (78 patients recruited in 2008-2015) or by Targeted NGS (201 patients recruited in 2016-2021) using Illumina platform, focused on the 54 genes related to SCN and neutropenia associated syndromes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11544122	For all BRET experiments, the NET BRET data is shown in Supplementary Fig. S14.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "all", "BRET", "experiments", ",", "the", "NET", ...
PMC11204465	This paper reviews the chemical diversity and potential activity and toxicity of sterigmatocystins and aflatoxins, enhances the understanding of sterigmatocystins and aflatoxins that adversely affect humans and animals, and provides ideas for their prevention, research and development.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	However, in the presence of daratumumab (ADCC) these percentages showed a similar tendency although not significant: 88.57%±3.77 vs 78.89%±5.57 in MOLP-8; 70.75%±5.69 vs 58.28%±7.52 for RPMI-8226; and 56.74%±7.25 vs 45.68%±7.1 in MM.1S.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9164404	We found here CLDN6 was also highly expressed in cells treated with Abplatin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "found", "here", "CLDN6", "was", "also", "highly", "expressed", ...
PMC11635087	The CHO-K1 cells were seeded at a density of 2.4 × 10 in a 35 mm glass-bottom dish (Iwaki) and pre-cultured for 12 hours.	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11637276	Alexa Fluor 647 Phalloidin, NHS-Fluorescein, NHS-Alexa Fluor 555, pHrodo iFL STP ester red, and Hoechst-33342 were from Invitrogen.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Alexa", "Flu...
PMC9368503	These tumours maintain the same histological features as the histology images deposited in The Jackson Laboratory biorepository database.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "tumours", "maintain", "the", ...
PMC11696576	The cell lines were not authenticated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cell", "lines", "were", "not", "authenticated", "." ] } ]
PMC9352806	High saturated fat can lead to problems such as elevated cholesterol, atherosclerosis, and increases LDL levels, while unsaturated fats can raise HDL levels (Sacks et al., 2017).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Image: Summary/Conclusion: DA-EPOCH-InO has a manageable toxicity profile with infrequent DLTs and only 1 case of SOS in heavily pre-treated adults with B-ALL.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10907726	50 μl DATS mother liquor was weighed to calculate the concentration of the mother liquor, which is 6.28 mol/L. DMSO(#D2650, Sigma, Germany) was used to dilute the concentration of DATS to 400 μM in 2 ml centrifuge tubes (Corning, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11437637	The manipulation was performed according to the manufacturer’s instructions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "manipulation", "was", "performed", "according", "to", "the", "manufacturer", "’s", "instr...
PMC7057940	The sections were counterstained with Harris's hematoxylin, dehydrated, coverslipped, and observed under an Olympus optical microscope BX53.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "sections", ...
PMC9917080	In this case, adaptive ER- stress occurs, which contributes to a change in genome expression aimed to increase the survival of these cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC6643347	A high viral production is commonly observed in CD4-positive T cells activated during acute infection .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "high", "viral", "production", "is", "commonly", "obser...
PMC11407042	The icons used in the graph abstract were downloaded from the Bioicons website (https://bioicons.com) with modifications.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "icons", "used", "in", "the", ...
PMC11680391	The second analysis employed a linear regression model to identify factors significantly associated with BTSCC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "second", "analysis", "employed", "a", "linear", "reg...
PMC6182045	The binding of bNAbs to rgp120 was detected with fluorescently labeled goat-anti-human polyclonal antibody.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "binding", "of", "bNAbs", "to", "rgp120", "was", "detected...
PMC11367146	A total of 1443 potential targets corresponding to these active compounds were identified with the canonical SMILES in the Swiss Target Prediction database (Table S1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10968586	Incubation of MCF-7 cell line with 50 μg/mL HT (≈324 μM) for 12 h was sufficient to trigger apoptosis , despite the fact that this result was not uniformly reproduced.	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Methods: Pediatric patients with SHA were enrolled.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Methods", ":", "Pediatric", "patients", "with", "SHA", "were", "enrolled", "." ] } ]
PMC11634794	However, the specific involvement of LAMP1 in renal carcinoma remains unexplored.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "specific", "involvement", "of", "LAMP1", "in", "renal", ...
PMC7612475	1 mL of 20xSSC was added to each slide and a coverslip placed on top before slides were placed under a UV lamp for 1.5 hours.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10495912	Reactive oxygen species The ROS production after exposing HepG2 cells to the dose of TQ (75 µM) and hydrogen peroxide (31.2 µM) increased significantly compared to the control group (p < 0.05 and < 0.001, respectively).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6034753	The results were shown as mean ± standard error (SE) for six independent experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", "were", "shown", "as", "mean", ...
PMC11775197	In recent years, PPAR, a nuclear transcription factor, has been the subject of considerable research interest among the scientific community.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC11395280	In vivo, using an inducible mouse model of T-ALL, we found that we were able to increase the survival of the mice treated with CCL198-83 when compared to non-treated controls.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	On the other hand, even in CR, the antibody titer in AML patients under maintenance therapy was significantly lower than that in patients under treatment-free observation (154.0 [126.0-289.0] U/ml vs 1630.0 [806.0-2454.0] U/ml, P=0.0003).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	This study is ongoing, with patients actively being enrolled in the monotherapy and CC-99282+rituximab combination expansion cohorts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "study", "is", "ongoing", ",", ...
PMC11116779	Due to their size and structure, MPs/NPs can enter the lungs (9), and recently, it has been shown that continuous exposition to MPs/NPs can induce potential respiratory occupational diseases, thus contributing to the induction of lung cancer (3, 7, 10).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11437637	However, further studies are needed to determine why immune cells, such as CD19+B and NK cells, were more likely to be inhibited during laparoscopic surgery .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11627133	Confocal images of fixed and permeabilized HEK293T cells expressing H2B‐GFP.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O" ], "tokens": [ "Confocal", "images", "of", "fixed", "and", "permeabilized", "HEK293", "T", ...
PMC10965315	Natural products have contained approximately 77% of all small molecules used in the treatment of different neoplasms (Sharifi‐Rad et al., 2019).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11742231	Potential for Drug Repositioning: The ability of MGATAF to predict responses across a wide range of drugs suggests its utility in drug repositioning efforts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10482220	G3BP BC domain inhibits arsenite-induced assembly of SGs. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "G3BP", "BC", "domain", "inhibits", "arsenite-induced", "assembly", "of", "SGs", ".", "(" ] } ]
PMC11770130	Primers are listed in Supplementary information, Table S14.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Primers", "are", "listed", "in", "Supplementary", "information", ",", "Table", "S14", "." ] } ]
PMC11049548	Contrarily, from the exo-metabolome point of view, the behavior of HGSOC_T cells (but not of HGSOC_A) is more similar to that of A2780cis cells than to that of A2780 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellL...
PMC9878562	However, we could not observe a chemotactic response of VAL cells towards dihydroxysterols (not shown).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "we", "could", ...
PMC9429973	Image: Summary/Conclusion: RUNX1 variants with a VAF above 40% were classified as germline in two out of 22 MN patients (9%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Phase I results were previously reported (Mita et al. Clin Cancer Res, 2020) and the recommended phase 2 dosing (RP2D) was established.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11515150	On day 6, NK cells were transduced with a lentiviral vector carrying 12 C VHH, a CD28-derived hinge, a CD28 transmembrane and intracellular domain and a CD3ζ signaling domain, in combination with the human IL-15 gene to generate 12 C CAR-NK cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4369959	In mouse SMMC-7721 xenograft model, 6-shogaol inhibited tumor growth by the activation of caspase-3 and inactivation of eIF2α .	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "mouse", "SMMC-7721", ...
PMC11683240	Therefore, PT was added to cells in the presence of α1AT either after preincubation or directly.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "PT", "was", "added", "to"...
PMC11695623	Relationship between DCUN1D5 expression and tumor immune cell infiltration. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Relationship", "between", "DCUN1D5", "expression", "and", "tumor", "immune", "cell", "infiltration", ...
PMC9111184	All the data were expressed as mean ± standard deviation of at least four replicates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "the", "data", "were", "expressed", "as", "mean", ...
PMC11075223	Meanwhile, quality evaluation indicators should be established by measuring the changes in the content of relevant components in the processed products.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Meanwhile", ...

PMC11721277

A group of four mice was used per data point.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "group", "of", "four", "mice", "was", "used", "per", "data", "point", "." ] } ]

PMC11756514

MBL binding was detected by flow cytometry using streptavidin-BV421 to detect bound biotinylated MBL.

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PMC10926885

However, studies examining the connection between NDE1 and cancer is still very rare.

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PMC11122631

for 429.2248).

[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "for", "429.2248", ")", "." ] } ]

PMC11267036

Cells without any treatments served as the control cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "without", "any", "treatments", "served", "as", "the", "control", "cells", "." ] } ]

PMC9581083

Antiviral drugs must enter infected cells and work, often resulting in a number of side effects (Wang and Yang, 2020; Wang and Yang, 2021b; Wang and Yang, 2022).

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PMC11377827

HeLa HRE-GFP reporter cells treated with 14-3-3 pan siRNA, 14-3-3 epsilon sgRNA or 14-3-3 zeta sgRNA were analysed by flow cytometry.

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PMC11727062

It has been found that mononosides significantly inhibit the proliferation of A375 cells in a dose-dependent manner.

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PMC9429973

TSAT escalation stopping rules were not met in any subject, but in the 14mg group, two subjects had a majority of individual TSAT values >40% through Day 15, as compared to none in the 7mg group.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11594641

Contrary to RAB27A KO A375 sEVs, the TSG101 level in dKO sEVs was not elevated compared to wild-type sEVs.

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PMC9429973

Patients also reported increase in PV-related symptoms (i.e., increased fatigue and worsening concentration).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "also", "reported", "increase", "in", "PV-r...

PMC9429973

We enrolled 230 AML pts with a median age of 75 years (range 25-94); 157 pts (68%) had >2 relevant comorbidities.

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PMC9429973

This abstract is an encore from the Society of Hematologic Oncology 2021 Annual Meeting.

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PMC11609529

In this study, we utilize ovarian cancer ES-2 cells as a YM-positive cancer cell model to investigate the mechanisms and functional roles of the endogenous YM fusion in cancer.

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PMC9351137

Once chromosome segregation is complete, the actomyosin contractile ring is assembled at the cleavage furrow and drives the constriction of the plasma membrane where abscission, the final stage of cytokinesis, will occur.

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PMC11707577

In particular, bacteria were grown in LB liquid supplemented with Kanamycin (25 mg L), Ampicillin (100 mg L), and 0.4 mm IPTG for 24 h. Next, the bacterial culture was centrifuged for 20 min at 12 000 g and the obtained supernatant was supplemented with PEG 8000 (4% w/v) and NaCl (3% w/v).

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PMC6267596

A profile plot showed protein expression patterns that identified 34 and 79 proteins as up-regulated that follow the same pattern, respectively, and 35 and 44 proteins follow the same pattern as down-regulated, respectively (Figure 4c and Figure 4h).

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PMC9592219

Then, the siRNA and Lipofectamine were incorporated, carefully mixed, and incubated at 14°C for 20 min.

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PMC11718031

Before the basal media screening fed-batch experiments, cells were passaged twice in the 100% basal medium.

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PMC11201989

Considering the role of PD-L1 in regulating immune synapse formation, and the striking similarities between immune synapse and the primary cilia, it is possible that PD-L1 might have a role in regulating primary cilia formation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9822769

Interestingly enough, the peak potential (Ep) trend is opposite to that of kinetics (k, see the t½ values in Table 1).

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PMC8973085

White solid [A] (89%); [B] (73%); mp: 205–207 °C (EtOH); IR (KBr, v, cm): 3434 (NH), 2222 (CN), 1705 (C=O), 1656 (C=O); H NMR (DMSO-d6): δ 2.25 (s, 3H, CH3), 2.32 (s, 3H, CH3), 4.95 (s, 2H, CH2), 7.09–8.14 (m, 13H, CH-Ar), 10.46 (bs, 1H, NH); C NMR (DMSO-d6): δ 21.31, 22.86, 39.73, 103.95, 115.45, 115.84, 115.97, 121.87, 121.91, 128.70, 128.74, 129.31, 129.53, 131.51, 133.99, 136.87, 139.89, 151.77, 158.29, 161.29, 164.12, 193.84; MS m/z (%): 495 [M] (65), 463 (5), 384 (100), 105 (55).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Binary logistic regression was used to develop a predictive scoring system.

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PMC11590870

As for amaranth hydrolysate, 1160 µg/mL led to a significant inhibition of ROS, keeping cells in the basal state .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "for", "amar...

PMC11730000

However, these differences were not significant compared with the DOX-treated group (Figure 7C).

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PMC11588085

In ovarian cancer, CD24 has been shown to be expressed in epithelial CSCs (62, 63).

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PMC9577200

According to our findings, the inhibition of chitosan carried out by the previous determination against BC was higher than PAO1 at all concentrations.

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PMC6617630

FISH was performed using standard FISH methodologies .

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PMC11721295

Double- and single-positive cells were counted and specified quantifications were performed.

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PMC11770130

The suppression of ceramides C20–C24 production in adipose tissue by depleting CerS2 downregulated food intake, but the local treatment of ceramides C20–C24 in vivo upregulated food intake.

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PMC11335267

Normally, Pomc/Cart neurons respond to leptin generated from the adipose tissue upon feeding , and as a consequence, they release αMSH to activate MC4R expressed in the paraventricular nucleus to promote satiety signals , to which co-released CART also contributes.

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PMC4659567

C NMR (CDCl3, ppm): δ 149.9 (C6), 149.3 (C7a), 133.8 (C4), 132.2 (C2), 126.1 (C3a), 112.1 (C5), 103.4 (C14), 97.9 (C11), 83.7 (C13, C15), 81.6 (C12, C16), 30.6 (C17), 22.2 (C18, C19), 18.2 (C20).

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PMC11621493

Changes in DAG and MAG are consistent with the high MMAT activity of PLA2G4D.

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PMC9429973

Summary/Conclusion: Sd was able to induce an encouraging response with a manageable safety profile for a group of Chinese RRMM patients desperately needing treatment after failing CAR-T therapy.

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PMC11708541

In order to create new aminopyridone derivatives and to check them for nootropic activity, the synthesis of compounds 61 based on amino-methyl—phenylpyridine was performed.

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PMC11597291

Such conjugation processes are used for the loading of drugs and small molecules, genes, antibodies, and aptamers on GO nanomaterials .

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PMC9429973

X.-H. Zhang, S. Chong, P. Zhao, R.-B. Huang, H. Zhou, J.-N. Zhang, Q.-S. Huang, H.-X. Fu, Q. Jiang, H. Jiang, J. Lu, X.-J. Huang Peking University People’s Hospital, Beijing; The First Affiliated Hospital of Nanchang University, NanChang; Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou; Peking University Cancer Hospital and Institute, Beijing, China Background: ITP is more likely to be persistent or chronic in adults, whereas it is a self-limiting disease in children.

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PMC8875242

The final concentration of DMSO was 0.1% in all experiments.

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PMC11802855

At 7 weeks, three out of five mice in the CXCL7-OE group exhibited symptoms of long bone fractures.

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PMC11706491

Table showing the mean ± SD of all the growth parameters that can be measured with the cell cycle reporter strain.

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PMC8711270

Current examples include the commercially available LV and AAV vector production workflow offered by Thermo Fisher Scientific, where their HEK293-derived Viral Production Cells (VPC) are used in the LV-MAX system and the upcoming VPC 2.0 used in their prototype AAV-MAX system.

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PMC9111184

Ezetimibe showed the highest permeability.

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PMC10914904

vtRNA 1-1, vtRNA 1-2, vtRNA 1-3 encode on locus 5q31.3, while vtRNA 2-1 is encoded on locus 5q31.

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PMC11718274

Imaging using TEM revealed a cubic shape and well dispersion of the ultra-sonicated Y2O3NPs in aqueous medium with a reduced mean particle’ size of 14.15 nm as depicted in Fig. 3.

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PMC11468365

An attention mechanism is adapted to customize the shared features for two distinct target tasks.

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PMC11088135

Protein bands were visualized with ECL detection kit (Beyotime).

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PMC11449273

Plakoglobin suppression of nuclear β-catenin localization in the H1299-PG-p53-175 cells could explain its anti-tumorigenic effect in these cells.

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PMC11594806

In a phase 2 trial for unresectable stage III non-small-cell lung cancer, adding oleclumab to durvalumab increased the objective response rate (ORR) from 17.9% to 30% and significantly extended PFS, with 12-month PFS rates rising from 33.9% to 62.6% .

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PMC9429973

Methods: A hematopathologist identifies a large B-cell lymphoma, and additional testing is ordered for further classification of the lymphoma (including Lymph3Cx analysis).

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PMC8097906

All statistical tests on metabolite profiles have been conducted in R (www.r-project.org) using the respective functions.

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PMC9621239

To verify this speculation, the mRNA and protein levels of MYC in HCC cell lines stably expressing wild-type HBx, mutant HBx and lentiviral empty vector were analysed using quantitative PCR (qPCR) and western blot assay, respectively.

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PMC8382973

The rabbits were 8 to 9 weeks old and weighed between 1.790 and 2.424 kg.

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PMC9268620

Conclusion: Therefore, we report that damnacanthal and nordamnacanthal exhibit anticancer properties by inducing apoptosis and necrosis in CEM-SS cells, and they have potential as a drug for the treatment of T-lymphoblastic leukemia.

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PMC9429973

Methods: Molecular analyses were performed either by direct Sanger sequencing (78 patients recruited in 2008-2015) or by Targeted NGS (201 patients recruited in 2016-2021) using Illumina platform, focused on the 54 genes related to SCN and neutropenia associated syndromes.

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PMC11544122

For all BRET experiments, the NET BRET data is shown in Supplementary Fig. S14.

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PMC11204465

This paper reviews the chemical diversity and potential activity and toxicity of sterigmatocystins and aflatoxins, enhances the understanding of sterigmatocystins and aflatoxins that adversely affect humans and animals, and provides ideas for their prevention, research and development.

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PMC9429973

However, in the presence of daratumumab (ADCC) these percentages showed a similar tendency although not significant: 88.57%±3.77 vs 78.89%±5.57 in MOLP-8; 70.75%±5.69 vs 58.28%±7.52 for RPMI-8226; and 56.74%±7.25 vs 45.68%±7.1 in MM.1S.

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PMC9164404

We found here CLDN6 was also highly expressed in cells treated with Abplatin.

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PMC11635087

The CHO-K1 cells were seeded at a density of 2.4 × 10 in a 35 mm glass-bottom dish (Iwaki) and pre-cultured for 12 hours.

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PMC11637276

Alexa Fluor 647 Phalloidin, NHS-Fluorescein, NHS-Alexa Fluor 555, pHrodo iFL STP ester red, and Hoechst-33342 were from Invitrogen.

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PMC9368503

These tumours maintain the same histological features as the histology images deposited in The Jackson Laboratory biorepository database.

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PMC11696576

The cell lines were not authenticated.

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PMC9352806

High saturated fat can lead to problems such as elevated cholesterol, atherosclerosis, and increases LDL levels, while unsaturated fats can raise HDL levels (Sacks et al., 2017).

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PMC9429973

Image: Summary/Conclusion: DA-EPOCH-InO has a manageable toxicity profile with infrequent DLTs and only 1 case of SOS in heavily pre-treated adults with B-ALL.

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PMC10907726

50 μl DATS mother liquor was weighed to calculate the concentration of the mother liquor, which is 6.28 mol/L. DMSO(#D2650, Sigma, Germany) was used to dilute the concentration of DATS to 400 μM in 2 ml centrifuge tubes (Corning, USA).

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PMC11437637

The manipulation was performed according to the manufacturer’s instructions.

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PMC7057940

The sections were counterstained with Harris's hematoxylin, dehydrated, coverslipped, and observed under an Olympus optical microscope BX53.

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PMC9917080

In this case, adaptive ER- stress occurs, which contributes to a change in genome expression aimed to increase the survival of these cells.

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PMC6643347

A high viral production is commonly observed in CD4-positive T cells activated during acute infection .

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PMC11407042

The icons used in the graph abstract were downloaded from the Bioicons website (https://bioicons.com) with modifications.

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PMC11680391

The second analysis employed a linear regression model to identify factors significantly associated with BTSCC.

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PMC6182045

The binding of bNAbs to rgp120 was detected with fluorescently labeled goat-anti-human polyclonal antibody.

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PMC11367146

A total of 1443 potential targets corresponding to these active compounds were identified with the canonical SMILES in the Swiss Target Prediction database (Table S1).

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PMC10968586

Incubation of MCF-7 cell line with 50 μg/mL HT (≈324 μM) for 12 h was sufficient to trigger apoptosis , despite the fact that this result was not uniformly reproduced.

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PMC9429973

Methods: Pediatric patients with SHA were enrolled.

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PMC11634794

However, the specific involvement of LAMP1 in renal carcinoma remains unexplored.

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PMC7612475

1 mL of 20xSSC was added to each slide and a coverslip placed on top before slides were placed under a UV lamp for 1.5 hours.

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PMC10495912

Reactive oxygen species The ROS production after exposing HepG2 cells to the dose of TQ (75 µM) and hydrogen peroxide (31.2 µM) increased significantly compared to the control group (p < 0.05 and < 0.001, respectively).

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PMC6034753

The results were shown as mean ± standard error (SE) for six independent experiments.

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PMC11775197

In recent years, PPAR, a nuclear transcription factor, has been the subject of considerable research interest among the scientific community.

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PMC11395280

In vivo, using an inducible mouse model of T-ALL, we found that we were able to increase the survival of the mice treated with CCL198-83 when compared to non-treated controls.

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PMC9429973

On the other hand, even in CR, the antibody titer in AML patients under maintenance therapy was significantly lower than that in patients under treatment-free observation (154.0 [126.0-289.0] U/ml vs 1630.0 [806.0-2454.0] U/ml, P=0.0003).

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PMC9429973

This study is ongoing, with patients actively being enrolled in the monotherapy and CC-99282+rituximab combination expansion cohorts.

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PMC11116779

Due to their size and structure, MPs/NPs can enter the lungs (9), and recently, it has been shown that continuous exposition to MPs/NPs can induce potential respiratory occupational diseases, thus contributing to the induction of lung cancer (3, 7, 10).

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PMC11437637

However, further studies are needed to determine why immune cells, such as CD19+B and NK cells, were more likely to be inhibited during laparoscopic surgery .

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PMC11627133

Confocal images of fixed and permeabilized HEK293T cells expressing H2B‐GFP.

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PMC10965315

Natural products have contained approximately 77% of all small molecules used in the treatment of different neoplasms (Sharifi‐Rad et al., 2019).

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PMC11742231

Potential for Drug Repositioning: The ability of MGATAF to predict responses across a wide range of drugs suggests its utility in drug repositioning efforts.

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PMC10482220

G3BP BC domain inhibits arsenite-induced assembly of SGs. (

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PMC11770130

Primers are listed in Supplementary information, Table S14.

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PMC11049548

Contrarily, from the exo-metabolome point of view, the behavior of HGSOC_T cells (but not of HGSOC_A) is more similar to that of A2780cis cells than to that of A2780 cells.

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PMC9878562

However, we could not observe a chemotactic response of VAL cells towards dihydroxysterols (not shown).

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PMC9429973

Image: Summary/Conclusion: RUNX1 variants with a VAF above 40% were classified as germline in two out of 22 MN patients (9%).

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PMC9429973

Phase I results were previously reported (Mita et al. Clin Cancer Res, 2020) and the recommended phase 2 dosing (RP2D) was established.

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PMC11515150

On day 6, NK cells were transduced with a lentiviral vector carrying 12 C VHH, a CD28-derived hinge, a CD28 transmembrane and intracellular domain and a CD3ζ signaling domain, in combination with the human IL-15 gene to generate 12 C CAR-NK cells.

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PMC4369959

In mouse SMMC-7721 xenograft model, 6-shogaol inhibited tumor growth by the activation of caspase-3 and inactivation of eIF2α .

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PMC11683240

Therefore, PT was added to cells in the presence of α1AT either after preincubation or directly.

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PMC11695623

Relationship between DCUN1D5 expression and tumor immune cell infiltration. (

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PMC9111184

All the data were expressed as mean ± standard deviation of at least four replicates.

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PMC11075223

Meanwhile, quality evaluation indicators should be established by measuring the changes in the content of relevant components in the processed products.

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