OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC2362953	CIK cells were transfected with a plasmid containing the interleukin-2 (IL-2) gene via electroporation.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CIK", "cells", "were", "transfected", "with", ...
PMC9577200	The turbidity of both bacterial strains significantly (p < 0.05) decreased with increasing chitosan concentrations, whereas, in the absence of CS, the turbidity increased in the function of time (control).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11534035	At the same time, no tendencies in the cell behavior were discovered under this treatment either.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "the", "same", "time", ",", "no", ...
PMC9429973	Platelets significantly decreased NK-mediated cytotoxicity in the SLe enriched (P=0.0025) but not in the parental MM cells, confirming the important role of sialofucosylation in platelet binding.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11089031	We performed IHC staining to analyze the distribution of ZNF692-expressing cells in tumor-adjacent tissues (C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "performed", "IHC", "staining", "to", ...
PMC9429973	Aims: To review the rates of blood transfusions from 2013 to 2021, and compare our adherence to NICE guidance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "To",...
PMC8348645	All the leaves (Figure 1) were washed with tap water and dried at normal room temperature for a week.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "the", "lea...
PMC10213179	The equilibrium binding constant was then calculated as the aptamer concentration needed to achieve a half-maximum binding at equilibrium [Y = Bmax × X/(Kd + X)].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11461874	pRL-SV40 was purchased from Promega (#E2231).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "pRL-SV40", "was", "purchased", "from", "Promega", "(", "#", "E2231", ")", "." ] } ]
PMC11634794	Overexpression of LAMP1 was observed in clinical specimens of prostate cancer and metastatic prostate cancer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overexpression", "of", "LAMP1", "was", "observed", "in", "c...
PMC6450504	a–d) Stability of PEIPOS upon incubation in 10% (v/v) FBS in PBS pH 7.4 at 37 °C for over 24h. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11731614	Kamil K. Gebis: Methodology.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Kamil", "K.", "Gebis", ":", "Methodology", "." ] } ]
PMC4443654	Regions undergoing a B to A compartment transition, to a relatively transcriptionally permissive structure, were enriched for cell-type-specific enhancers in the two derived cell types used in this study but not in the ESC line, which would not be expected to have lineage-specific enhancer contacts active in its plurip...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Although multiple other cancer types including breast, colon, and pancreatic cancer has been found to respond similarly to antioxidants, little is known about the effects in hematologic malignancies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11462673	LDB1 emerges as a critical transcription factor co-activator in cell lines derived from T-ALL.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "LDB1", "emerges", "as", "a", "critical", "transcription", "factor", ...
PMC9429973	FLT3 mutations worsened the prognosis but offer a targeted therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "FLT3", "mutations", "worsened", "the", "prognosis", "but", "offer", "a", "targeted", "therapy", ...
PMC11476106	The current standard treatment for ES is a multimodal approach consisting of conventional chemotherapy and surgery established through collaborative international trials, which has led to an improved overall survival (OS) rate of approximately 85% .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11674146	Therefore, our study aimed to investigate the role of CLP36 in lymphoma by regulating the PI3K/AKT/CREB signaling pathway.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "our", "study", ...
PMC9429973	Aims: The aim of this study was to investigate real-world treatment patterns and the outcomes for patients with MCL following cBTKi treatment utilizing two separate datasets—one from the US and one from Japan.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	MYC/BCL2 co-expression is an adverse predictive factor for response to chemotherapy regimens, and associateswith a significantly lower probability of complete remission.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MYC/BCL2", "...
PMC9920575	Cisplatin induced apoptosis in both cell lines (Figure 4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cisplatin", "induced", "apoptosis", "in", "both", "cell", "lines", "(", "Figure", "4"...
PMC11391695	For the fabrication of nano-drug-carrier membranes derived from HCC cells, a PEI-loaded PLGA core was coated (PEI/NPs).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "the", "fabrication", ...
PMC11509224	This is the first report of meroditerpenes inhibiting PTP1B activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "is", "the", "first", "report", "of", "meroditerpenes", "inhibiting", "PTP1B", "activity"...
PMC10728200	After treatment with RSL3, the expression of GPX4 and Ki-67 was decreased and the expression of 4-HNE was increased.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "treatment", "with",...
PMC11655536	More importantly, TFE3 knockdown could partially restore cell viability in the presence of HA (Fig. S4D, E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "More", "importantly", ...
PMC10197932	A method to evaluate the red blood viability (membrane integrity) is measuring Calcein-AM uptake and its retention.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "method", "to", "evaluate", ...
PMC11462673	4Transcriptome analyses show dysregulated self-renewal in LDB1-knockdown T-ALL cell.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "4Transcriptome", "analyses", "show", "dysregulated", "self-renewal", "in", "LDB1-knockdown", "T-ALL", "cell", ...
PMC10933092	Representative RNA mA modification peaks in sh-NC and sh-TRMT61A 5637 cells (the horizontal axis represents human chromosomes, and the vertical axis indicates mA enrichment). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11534377	FOXO3, a gene that contributes to cell cycle arrest and apoptosis, was upregulated with a FC of 2.7578971 (log FC = 1.4635687, p = 8.18E-04).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11470381	Create binary masks for each cell across all time frames within each delineated trajectory ROI, as specified above.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Create", "binary", "masks", "for"...
PMC8750422	We found that GPR87-overexpressing A549 and A427 cells displayed dramatically increased cancer cell invasion compared to control cells (Figure 1b).	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "...
PMC10197932	This can be explained probably by a different regulation of P53 during the first hours.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "can", "be", "explained", "probably", "by", "a", ...
PMC11750161	Taken together, PKA signaling via LH/CGR-mediated signaling must be further studied to determine whether any pathway involving the phosphorylation of downstream effectors of the MAPK pathway exists.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7868205	Dev.4.79R0.7413Mean429.45Adjusted R0.5084C.V. %1.11Predicted R−1.4496Adeq Precision8.0669 Figure 1Response surface plots and contour plots for the synthesized AgNPs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Dev.4.79R0.7413Mean429.45Adjusted", "R0.5084C.V.", "%", ...
PMC11704834	Consistent with this finding, forced upregulation of E-cadherin in exogenous TLE1 expressing HCC827 cell line which exhibited decreased E-cadherin expression similarly attenuated the TLE1-mediated gefitinib resistance (Fig. S4A and B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9275501	The results of in vitro release experiments showed that the benzoic acid-imine bond was relatively stable in neutral medium, and the hydrophilic PEG layer prevented the outward diffusion of hydrophobic drugs and limited the drug release.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11536589	The nude mice were subcutaneously implanted with 3 × 10 KPC210-MR cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "The", "nude", "mice", "were", "subcutaneously", "implanted", "with", "3", ...
PMC11380329	Among the different honeybee products, propolis (P) serves a valuable source contributing directly to human nutrition and health .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Among", "the", "d...
PMC10547921	The general mechanism of action of ADCs; (B) The mechanism of DNA inhibitors as ADC payloads; (C) The mechanism of Splicing inhibitors as ADC payloads; (D) The mechanism of tubulin inhibitors as ADC payloads; (E) The mechanism of PROTAC molecules as ADC payloads; (F) The mechanism of Bcl-xL inhibitors and proteasome in...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9341513	The changes to the chromatin states at CCND1 have a striking effect on the 3D structure of the gene: In Figure 6A, we plot the distribution of the simulated 3D size of the gene body (quantified by the radius of gyration, Rg) (see Supplemental Methods).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Methods: We included patients with an active diagnosis of haematological malignancy, or those who had received potentially curative treatment within the past 3 years.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11787381	Properties of liposomes and liposomes included in gel were presented in Supplementary table 1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Properties", "of", "liposomes", "and", "liposomes", "included", "in", ...
PMC9429973	Within the GCV group, 411 (44.2%) pts were exposed to ganciclovir alone, 276 (29.7%) pts to valganciclovir alone and 159 (17.1%) pts to both drugs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Internal tandem duplications (ITD) in FLT3 receptor appear in 30% of cases and is associated with poor disease outcome.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Internal", "...
PMC11739696	Integrity of genomic DNA in the melanoma A-375 cells following exposure to IC50 concentration of Co3O4NPs for 72 h. Results are expressed as mean ± SD. , *:	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11539788	P < 0.05, P < 0.01, and *P < 0.001 Knockdown of RNF19A promoted cell proliferation, migration, invasion, and the EMT in BCa cells. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10568263	CV was recorded between −0.2 and 0.6 V potential at a scan rate of 50 mV s. EIS was performed at a frequency range of 0.2–1000 Hz with 5 mV AC amplitude.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11765678	Residues within the box were assumed to have flexible side chains, and the exhaustiveness level was set to 32.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Residues", "within", "the", ...
PMC11055510	p < 0.05.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "p", "<", "0.05", "." ] } ]
PMC11638255	Data are presented as mean ± SEM, n = 4 (both groups) biological replicates, one independent experiment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "pr...
PMC7022782	The loading of PECA-NPs with a fluorescent dye allows us to investigate the interaction of NPs themselves with a cancer cell-substrate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "loading", ...
PMC5941560	Translocation19811981Inter.	[ { "tags": [ "O", "O" ], "tokens": [ "Translocation19811981Inter", "." ] } ]
PMC11320834	Data are given as the mean value ± SD from three independent experiments The relatively simple composition of TLL and OLL used in the preliminary studies, which encompasses EPC and cholesterol, affects the long-term stability of liposomes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11588008	GSH exists as the forms of thiol-reduced and disulfide-oxidized.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GSH", "exists", "as", "the", "forms", "of", "thiol-reduced", "and", "disulfide-oxidized", "." ] } ]
PMC9621239	β-actin was used as a loading control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "β-actin", "was", "used", "as", "a", "loading", "control", "." ] } ]
PMC9398137	y axis shows calculated tumor volumes in the individual treatment cohorts calculated from three perpendicular tumor dimensions (6–8 mice per cohort, means ± SDs).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11679892	This study investigated the anticancer potential of Pelargonium sidoides root extract on the human neuroblastoma cell line (SH-SY5Y).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "B-CellLine", "O", "O" ], "tokens": [ "This...
PMC9429973	Results: The mean age of patients and controls was 40.8 ± 10.5 years with extremes of 18 and 59 years.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "T...
PMC11536589	Consequently, these treatment outcomes are generally unfavorable (Hosein et al. 2022).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consequently", ",", "these", "treatment", "outcomes", "are", "generall...
PMC4270159	FGF activates pFRS2 and pERK in the presence of Sunitinib. •	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "FGF", "activates", "pFRS2", "and", "pERK", "in", "the", "presence", "of", "Sunitinib"...
PMC3274243	Unlike impedance based biosensor technology the flow of current in the Oncoprobe system is effectively negligible due to the high impedance employed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Unlike", "im...
PMC9918897	The authorization number is PE/EA/1412-6/2016.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "authorization", "number", "is", "PE/EA/1412", "-", "6/2016", "." ] } ]
PMC9429973	A. Koviazin, L. Filatova, I. Zyuzgin, A. Artemyeva, M. Motalkina, Y. Chudinovskikh, S. Volchenkov, I. Poliatskin, E. Dobrovolskaya, S. Shalaev, I. Ishmatova, A. Zverkova, D. Burda, S. Elkhova, T. Semiglazova Department of Hematology and Chemotherapy with intensive care unit, NMRC of Oncology named after N.N.Petrov of M...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11394730	According to the authors of , who demonstrated that the tumor cells are weakened, effective anti-tumor therapy is supported by a low pH tumor microenvironment, which is linked to several aspects such as reduced vascularization, food deprivation, and hypoxia in the setting of the Warburg effect.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11365983	PDGFRα signaling has well characterized roles that encompass formation of neural crest derived tissues, and multiple aspects of CNS development.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PDGFRα", "signaling", ...
PMC11507371	Accordingly, Yan et al. , who reviewed the existing literature comparing cancer cells to normal cells from the same tissue type, classified CAP’s effect on SCC as strongly selective.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11371747	Cells were exposed for 4 h to the drugs in a concentration range, while the leucovorin (LV) formulations were added simultaneously.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC6617630	After 24 h, cells were harvested and CD47 expression was determined by flow cytometry BETi mediated transcriptional repression of MYC or BCL6 appears to have little effect on survival of DHL or THL DLBCL cells despite robust anti-proliferative activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11772585	Mechanistically, we confirmed that METTL1 could induce the m7G modification of the ATF4 mRNA to enhance its stability.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mechanistically", ",", "we",...
PMC7823217	Achieving rapid maturation of bioprinted construct is key especially when these are utilized for screening of personalized anti-cancer therapies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Achieving", "rapid", "maturation", ...
PMC11473750	Chromosomal disomy was defined as average gene copy number of 1.20–2.40, trisomy 2.40–3.40 and polysomy >3.40.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Chromosomal", "disomy", "was", "defined", ...
PMC10547921	Calicheamicins target small grooves that bind to DNA and specifically induce DNA double-strand breakage, leading to apoptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Calicheamicins", "target", "small", "grooves...
PMC11763126	Co-IP results validated the interaction between YTHDF2 and USP5 (Fig. 8B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Co-IP", "results", "validated", "the", "interaction", "between", "YTHDF2", ...
PMC9817179	These are the average exchange rates between and and do not concern the potential spatial inhomogeneity in the rates at the molecular level.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These",...
PMC10998613	Fractional correlation of β2AR shows weak homomultimerization in MDA-MB-231 and COS-7 cells. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "Fractional", "correlation", "of", "β2AR", "shows", "weak", "hom...
PMC11687167	The p38 MAPK regulates T-cell activation by selectively activating nuclear factor of activated T cells c1 (NFATc1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "p38", "MAPK", "regulates",...
PMC11739484	Differences in MMP expression levels between SKCM and control groups were evaluated using unpaired Student’s t-tests.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Differences", "in", "MMP", "expression", "levels"...
PMC11535726	Conidiogenous cells 6.5–16 × 5–9 μm (x̄ = 13× 7 μm, n = 20), monoblastic, terminal or indeterminate, percurrently proliferating, cylindrical, pale brown to brown.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5916734	Negative agarose gel images; the membrane images were contrast-enhanced to add visibility.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Negative", "agarose", "gel", "images", ";", "the", "membrane", "images", ...
PMC9429973	To date, 77.2 % of the patients have successfully completed the program.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "date", ",", "77.2", "%", "of", "the", "patients", "have", ...
PMC10994876	Two-way ANOVA was employed to conduct statistical analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Two-way", "ANOVA", "was", "employed", "to", "conduct", "statistical", "analysis", "." ] } ]
PMC10729469	Mice were then pericardially perfused with PBS, and brains and lymph nodes (axial, cervical and inguinal) were harvested.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mice", "were...
PMC11683130	The expression of SerpinB7 in psoriasis is controversial, which requires further studies to confirm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "expression", "of", "SerpinB7", "in", "psoriasis", "i...
PMC11803918	Apart from melanoma, our photoresponsive strategy might also be suitable to provide safe and efficient treatment for other high malignancy tumor types, such as retinoblastoma, colon cancer, breast cancer, etc.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11727062	Studies have shown that 10-gingerol inhibits the viability and proliferation of A375 melanoma cells in a dose-dependent manner.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Studies", "have", "shown", "that", ...
PMC11367146	This study received no funds or any extramural research grants Data will be made available on request.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "study", "received", "no", "funds", ...
PMC9429973	Aims: To reveal the experience of our Centre on the treatment of aggressive B-cell lymphoma with DA-EPOCH-R Methods: We retrospectively collected data from 54 consecutive patients treated with DA-EPOCH-R in our Department.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10698968	For the MFS cell line, amphotericin B (Lonza) was added to the medium in the first passages.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "the", "MFS", "c...
PMC9429973	Loss of CD33 and CLL-1 proteins did not impact myeloid and erythroid potential or differentiation into granulocytic or monocytic lineages in vitro.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Loss", "of",...
PMC9780037	Reductive chemical environment in the cell cleaves the linkers, leaving the pores open to release cyt c (Figure 3E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Reductive", ...
PMC11128598	To measure HR efficiency in stable pools, cells were first preincubated with LBH for 24 h. Then, 10 cells were cotransfected with 5 μg of a plasmid that express the endonuclease I-SceI and 0.5 μg of pDsRed-N1 (Clontech, Palo Alto, CA, USA, Cat.632429) to correct for differences in transfection efficiencies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11144200	HPLC-MS was performed to detect DOX concentration in the exfoliated tumors, as well as the outcomes corresponded with the above (Fig. 4H, J).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11674891	HRP-conjugated anti-mouse and anti-rabbit IgG antibodies (Bio-Rad, Hercules, CA, USA) were used as secondary antibodies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HRP-conjugated", "anti-mouse", ...
PMC9672323	Significant changes are indicated with asterisk (p < 0.05, p < 0.01, p < 0.001, **p < 0.0001).Figure 2The effect of drugs on the proliferation of T cells in PBMCs in stimulated and non-stimulated conditions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4485648	In agreement with the reduced HIF-1α protein level, SFN was able to diminish the hypoxia-induced activation of the CA9 gene promoter almost to its normoxic value as determined by the dual luciferase assay (Fig. 3A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10734950	The same controls were used in this experiment as those presented in the above sections.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "same", "controls", "were", "used", "in", "this", ...
PMC10114490	Nevertheless, we still found some differences between PD and PD diHLC-T, in terms of gene expression, xenobiotic metabolism and toxicity, but those differences were less significant compared to differences found between cells from different donors .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11768281	Antigen-presenting cells (APCs), including dendritic cells (DCs) and macrophages, play a crucial role in the pre-activation of T-cells by presenting Plasmodium antigens.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11790971	The results from passage 0, passage 1, and passage 2 are shown in (a, d), (b, e), and (c, f), respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11367146	The red and blue colour gradient indicates the up and down regulatory genes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "red", "and", "blue", "colour", "gradient", "indicates", "the", ...

PMC2362953

CIK cells were transfected with a plasmid containing the interleukin-2 (IL-2) gene via electroporation.

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PMC9577200

The turbidity of both bacterial strains significantly (p < 0.05) decreased with increasing chitosan concentrations, whereas, in the absence of CS, the turbidity increased in the function of time (control).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11534035

At the same time, no tendencies in the cell behavior were discovered under this treatment either.

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PMC9429973

Platelets significantly decreased NK-mediated cytotoxicity in the SLe enriched (P=0.0025) but not in the parental MM cells, confirming the important role of sialofucosylation in platelet binding.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11089031

We performed IHC staining to analyze the distribution of ZNF692-expressing cells in tumor-adjacent tissues (C).

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PMC9429973

Aims: To review the rates of blood transfusions from 2013 to 2021, and compare our adherence to NICE guidance.

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PMC8348645

All the leaves (Figure 1) were washed with tap water and dried at normal room temperature for a week.

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PMC10213179

The equilibrium binding constant was then calculated as the aptamer concentration needed to achieve a half-maximum binding at equilibrium [Y = Bmax × X/(Kd + X)].

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PMC11461874

pRL-SV40 was purchased from Promega (#E2231).

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PMC11634794

Overexpression of LAMP1 was observed in clinical specimens of prostate cancer and metastatic prostate cancer.

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PMC6450504

a–d) Stability of PEIPOS upon incubation in 10% (v/v) FBS in PBS pH 7.4 at 37 °C for over 24h. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11731614

Kamil K. Gebis: Methodology.

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Kamil", "K.", "Gebis", ":", "Methodology", "." ] } ]

PMC4443654

Regions undergoing a B to A compartment transition, to a relatively transcriptionally permissive structure, were enriched for cell-type-specific enhancers in the two derived cell types used in this study but not in the ESC line, which would not be expected to have lineage-specific enhancer contacts active in its plurip...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Although multiple other cancer types including breast, colon, and pancreatic cancer has been found to respond similarly to antioxidants, little is known about the effects in hematologic malignancies.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11462673

LDB1 emerges as a critical transcription factor co-activator in cell lines derived from T-ALL.

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PMC9429973

FLT3 mutations worsened the prognosis but offer a targeted therapy.

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PMC11476106

The current standard treatment for ES is a multimodal approach consisting of conventional chemotherapy and surgery established through collaborative international trials, which has led to an improved overall survival (OS) rate of approximately 85% .

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PMC11674146

Therefore, our study aimed to investigate the role of CLP36 in lymphoma by regulating the PI3K/AKT/CREB signaling pathway.

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PMC9429973

Aims: The aim of this study was to investigate real-world treatment patterns and the outcomes for patients with MCL following cBTKi treatment utilizing two separate datasets—one from the US and one from Japan.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

MYC/BCL2 co-expression is an adverse predictive factor for response to chemotherapy regimens, and associateswith a significantly lower probability of complete remission.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MYC/BCL2", "...

PMC9920575

Cisplatin induced apoptosis in both cell lines (Figure 4).

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PMC11391695

For the fabrication of nano-drug-carrier membranes derived from HCC cells, a PEI-loaded PLGA core was coated (PEI/NPs).

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PMC11509224

This is the first report of meroditerpenes inhibiting PTP1B activity.

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PMC10728200

After treatment with RSL3, the expression of GPX4 and Ki-67 was decreased and the expression of 4-HNE was increased.

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PMC11655536

More importantly, TFE3 knockdown could partially restore cell viability in the presence of HA (Fig. S4D, E).

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PMC10197932

A method to evaluate the red blood viability (membrane integrity) is measuring Calcein-AM uptake and its retention.

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PMC11462673

4Transcriptome analyses show dysregulated self-renewal in LDB1-knockdown T-ALL cell.

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PMC10933092

Representative RNA mA modification peaks in sh-NC and sh-TRMT61A 5637 cells (the horizontal axis represents human chromosomes, and the vertical axis indicates mA enrichment). (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11534377

FOXO3, a gene that contributes to cell cycle arrest and apoptosis, was upregulated with a FC of 2.7578971 (log FC = 1.4635687, p = 8.18E-04).

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PMC11470381

Create binary masks for each cell across all time frames within each delineated trajectory ROI, as specified above.

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PMC8750422

We found that GPR87-overexpressing A549 and A427 cells displayed dramatically increased cancer cell invasion compared to control cells (Figure 1b).

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PMC10197932

This can be explained probably by a different regulation of P53 during the first hours.

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PMC11750161

Taken together, PKA signaling via LH/CGR-mediated signaling must be further studied to determine whether any pathway involving the phosphorylation of downstream effectors of the MAPK pathway exists.

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PMC7868205

Dev.4.79R0.7413Mean429.45Adjusted R0.5084C.V. %1.11Predicted R−1.4496Adeq Precision8.0669 Figure 1Response surface plots and contour plots for the synthesized AgNPs.

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PMC11704834

Consistent with this finding, forced upregulation of E-cadherin in exogenous TLE1 expressing HCC827 cell line which exhibited decreased E-cadherin expression similarly attenuated the TLE1-mediated gefitinib resistance (Fig. S4A and B).

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PMC9275501

The results of in vitro release experiments showed that the benzoic acid-imine bond was relatively stable in neutral medium, and the hydrophilic PEG layer prevented the outward diffusion of hydrophobic drugs and limited the drug release.

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PMC11536589

The nude mice were subcutaneously implanted with 3 × 10 KPC210-MR cells.

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PMC11380329

Among the different honeybee products, propolis (P) serves a valuable source contributing directly to human nutrition and health .

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PMC10547921

The general mechanism of action of ADCs; (B) The mechanism of DNA inhibitors as ADC payloads; (C) The mechanism of Splicing inhibitors as ADC payloads; (D) The mechanism of tubulin inhibitors as ADC payloads; (E) The mechanism of PROTAC molecules as ADC payloads; (F) The mechanism of Bcl-xL inhibitors and proteasome in...

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PMC9341513

The changes to the chromatin states at CCND1 have a striking effect on the 3D structure of the gene: In Figure 6A, we plot the distribution of the simulated 3D size of the gene body (quantified by the radius of gyration, Rg) (see Supplemental Methods).

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PMC9429973

Methods: We included patients with an active diagnosis of haematological malignancy, or those who had received potentially curative treatment within the past 3 years.

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PMC11787381

Properties of liposomes and liposomes included in gel were presented in Supplementary table 1.

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PMC9429973

Within the GCV group, 411 (44.2%) pts were exposed to ganciclovir alone, 276 (29.7%) pts to valganciclovir alone and 159 (17.1%) pts to both drugs.

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PMC9429973

Internal tandem duplications (ITD) in FLT3 receptor appear in 30% of cases and is associated with poor disease outcome.

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PMC11739696

Integrity of genomic DNA in the melanoma A-375 cells following exposure to IC50 concentration of Co3O4NPs for 72 h. Results are expressed as mean ± SD. **, ***:

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PMC11539788

P < 0.05, **P < 0.01, and ***P < 0.001 Knockdown of RNF19A promoted cell proliferation, migration, invasion, and the EMT in BCa cells. (

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PMC10568263

CV was recorded between −0.2 and 0.6 V potential at a scan rate of 50 mV s. EIS was performed at a frequency range of 0.2–1000 Hz with 5 mV AC amplitude.

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PMC11765678

Residues within the box were assumed to have flexible side chains, and the exhaustiveness level was set to 32.

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PMC11055510

p < 0.05.

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PMC11638255

Data are presented as mean ± SEM, n = 4 (both groups) biological replicates, one independent experiment.

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PMC7022782

The loading of PECA-NPs with a fluorescent dye allows us to investigate the interaction of NPs themselves with a cancer cell-substrate.

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PMC5941560

Translocation19811981Inter.

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PMC11320834

Data are given as the mean value ± SD from three independent experiments The relatively simple composition of TLL and OLL used in the preliminary studies, which encompasses EPC and cholesterol, affects the long-term stability of liposomes.

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PMC11588008

GSH exists as the forms of thiol-reduced and disulfide-oxidized.

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PMC9621239

β-actin was used as a loading control.

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PMC9398137

y axis shows calculated tumor volumes in the individual treatment cohorts calculated from three perpendicular tumor dimensions (6–8 mice per cohort, means ± SDs).

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PMC11679892

This study investigated the anticancer potential of Pelargonium sidoides root extract on the human neuroblastoma cell line (SH-SY5Y).

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PMC9429973

Results: The mean age of patients and controls was 40.8 ± 10.5 years with extremes of 18 and 59 years.

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PMC11536589

Consequently, these treatment outcomes are generally unfavorable (Hosein et al. 2022).

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PMC4270159

FGF activates pFRS2 and pERK in the presence of Sunitinib. •

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PMC3274243

Unlike impedance based biosensor technology the flow of current in the Oncoprobe system is effectively negligible due to the high impedance employed.

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PMC9918897

The authorization number is PE/EA/1412-6/2016.

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PMC9429973

A. Koviazin, L. Filatova, I. Zyuzgin, A. Artemyeva, M. Motalkina, Y. Chudinovskikh, S. Volchenkov, I. Poliatskin, E. Dobrovolskaya, S. Shalaev, I. Ishmatova, A. Zverkova, D. Burda, S. Elkhova, T. Semiglazova Department of Hematology and Chemotherapy with intensive care unit, NMRC of Oncology named after N.N.Petrov of M...

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PMC11394730

According to the authors of , who demonstrated that the tumor cells are weakened, effective anti-tumor therapy is supported by a low pH tumor microenvironment, which is linked to several aspects such as reduced vascularization, food deprivation, and hypoxia in the setting of the Warburg effect.

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PMC11365983

PDGFRα signaling has well characterized roles that encompass formation of neural crest derived tissues, and multiple aspects of CNS development.

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PMC11507371

Accordingly, Yan et al. , who reviewed the existing literature comparing cancer cells to normal cells from the same tissue type, classified CAP’s effect on SCC as strongly selective.

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PMC11371747

Cells were exposed for 4 h to the drugs in a concentration range, while the leucovorin (LV) formulations were added simultaneously.

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PMC6617630

After 24 h, cells were harvested and CD47 expression was determined by flow cytometry BETi mediated transcriptional repression of MYC or BCL6 appears to have little effect on survival of DHL or THL DLBCL cells despite robust anti-proliferative activity.

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PMC11772585

Mechanistically, we confirmed that METTL1 could induce the m7G modification of the ATF4 mRNA to enhance its stability.

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PMC7823217

Achieving rapid maturation of bioprinted construct is key especially when these are utilized for screening of personalized anti-cancer therapies.

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PMC11473750

Chromosomal disomy was defined as average gene copy number of 1.20–2.40, trisomy 2.40–3.40 and polysomy >3.40.

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PMC10547921

Calicheamicins target small grooves that bind to DNA and specifically induce DNA double-strand breakage, leading to apoptosis.

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PMC11763126

Co-IP results validated the interaction between YTHDF2 and USP5 (Fig. 8B).

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PMC9817179

These are the average exchange rates between and and do not concern the potential spatial inhomogeneity in the rates at the molecular level.

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PMC10998613

Fractional correlation of β2AR shows weak homomultimerization in MDA-MB-231 and COS-7 cells. (

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PMC11687167

The p38 MAPK regulates T-cell activation by selectively activating nuclear factor of activated T cells c1 (NFATc1).

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PMC11739484

Differences in MMP expression levels between SKCM and control groups were evaluated using unpaired Student’s t-tests.

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PMC11535726

Conidiogenous cells 6.5–16 × 5–9 μm (x̄ = 13× 7 μm, n = 20), monoblastic, terminal or indeterminate, percurrently proliferating, cylindrical, pale brown to brown.

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PMC5916734

Negative agarose gel images; the membrane images were contrast-enhanced to add visibility.

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PMC9429973

To date, 77.2 % of the patients have successfully completed the program.

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PMC10994876

Two-way ANOVA was employed to conduct statistical analysis.

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PMC10729469

Mice were then pericardially perfused with PBS, and brains and lymph nodes (axial, cervical and inguinal) were harvested.

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PMC11683130

The expression of SerpinB7 in psoriasis is controversial, which requires further studies to confirm.

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PMC11803918

Apart from melanoma, our photoresponsive strategy might also be suitable to provide safe and efficient treatment for other high malignancy tumor types, such as retinoblastoma, colon cancer, breast cancer, etc.

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PMC11727062

Studies have shown that 10-gingerol inhibits the viability and proliferation of A375 melanoma cells in a dose-dependent manner.

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PMC11367146

This study received no funds or any extramural research grants Data will be made available on request.

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PMC9429973

Aims: To reveal the experience of our Centre on the treatment of aggressive B-cell lymphoma with DA-EPOCH-R Methods: We retrospectively collected data from 54 consecutive patients treated with DA-EPOCH-R in our Department.

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PMC10698968

For the MFS cell line, amphotericin B (Lonza) was added to the medium in the first passages.

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PMC9429973

Loss of CD33 and CLL-1 proteins did not impact myeloid and erythroid potential or differentiation into granulocytic or monocytic lineages in vitro.

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PMC9780037

Reductive chemical environment in the cell cleaves the linkers, leaving the pores open to release cyt c (Figure 3E).

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PMC11128598

To measure HR efficiency in stable pools, cells were first preincubated with LBH for 24 h. Then, 10 cells were cotransfected with 5 μg of a plasmid that express the endonuclease I-SceI and 0.5 μg of pDsRed-N1 (Clontech, Palo Alto, CA, USA, Cat.632429) to correct for differences in transfection efficiencies.

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PMC11144200

HPLC-MS was performed to detect DOX concentration in the exfoliated tumors, as well as the outcomes corresponded with the above (Fig. 4H, J).

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PMC11674891

HRP-conjugated anti-mouse and anti-rabbit IgG antibodies (Bio-Rad, Hercules, CA, USA) were used as secondary antibodies.

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PMC9672323

Significant changes are indicated with asterisk (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001).Figure 2The effect of drugs on the proliferation of T cells in PBMCs in stimulated and non-stimulated conditions.

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PMC4485648

In agreement with the reduced HIF-1α protein level, SFN was able to diminish the hypoxia-induced activation of the CA9 gene promoter almost to its normoxic value as determined by the dual luciferase assay (Fig. 3A).

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PMC10734950

The same controls were used in this experiment as those presented in the above sections.

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PMC10114490

Nevertheless, we still found some differences between PD and PD diHLC-T, in terms of gene expression, xenobiotic metabolism and toxicity, but those differences were less significant compared to differences found between cells from different donors .

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PMC11768281

Antigen-presenting cells (APCs), including dendritic cells (DCs) and macrophages, play a crucial role in the pre-activation of T-cells by presenting Plasmodium antigens.

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PMC11790971

The results from passage 0, passage 1, and passage 2 are shown in (a, d), (b, e), and (c, f), respectively.

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PMC11367146

The red and blue colour gradient indicates the up and down regulatory genes.

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