OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC10955424	Consequently, inhibition of FASN in cisplatin resistance OC cells resulted in resistance mitigation .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consequently", ",", "inhibition", "of", "FASN", "in", "cisplatin", ...
PMC11271278	Although several of the identified oncogenes such as MYC, ETV1, and CCND1 have been previously linked to enhancer hijacking, we identified their novel hijacked enhancers that are cancer type specific.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11435360	Moreover, VEGF cells were further reduced in the BBN PAG + GEM group compared to the BBN PAG group (p < 0.05, Figure 4E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9688728	After thawing, the cells were cultured in DMEM/F12 supplemented with 10% fetal bovine serum and 100 units/mL penicillin/streptomycin (all from Gibco, Waltham, MA, USA) in a humidified CO2-incubator under standard conditions (5% CO2, 37 °C, 100% humidity).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	GFI1B aberrations are linked to inherited bleeding disorders, resulting in macro-thrombocytopenia, gray platelets and increased expression of CD34.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GFI1B", "aberrations", "are"...
PMC8956657	Firefly luciferase values were normalized to Renilla luciferase values.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Firefly", "luciferase", "values", "were", "normalized", "to", "Renilla", "luciferase", "values", "." ] ...
PMC10831439	The cytotoxicity of the effector cells was assessed in three technical replicates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cytotoxicity", "of", "the", "effector", "cells", "was", "assessed", "in",...
PMC10926885	To forecast miRNAs upstream of NDE1, we collected data from miRDB, miRWalk, miRabel and TrgetScan.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "forecast", "miRNAs", "upstream", ...
PMC9429973	For patients with a HES-related hospitalization, the mean (SD) length of stay (LoS) was 11.0 (9.4) days.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	Moreover, for the first time, we established AITL patient-derived organoid models that can be stablely cultured in vitro.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "for", ...
PMC7171147	GAPDH was used as a loading control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GAPDH", "was", "used", "as", "a", "loading", "control", "." ] } ]
PMC11011837	This opens the possibility of designing experiments to directly verify and confirm the obtained results in patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "opens", "the", "possibility", "of", ...
PMC11052306	In this review article, we present an overview of the use of a particular Schiff base, namely pyridine–imine, linked to the surface of dendrimers, suitable for complexing copper, and the use of such dendrimer complexes in biology, in particular against cancers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	While TNF-α 238 GA, AA, and GG account for (54.5, 39.5, and 6% respectively).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "While", "TNF-α", ...
PMC5173112	In current study, we showed that USP21 binds to the promoter region of IL-8 gene and regulates its transcriptional activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "current", "...
PMC9545474	HRMS‐ESI: calculated [M+H] 910.92807 m/z, found 910.92698 m/z. [(	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HRMS‐ESI", ":", "calculated", "[", "M+H", "]", "910.92807", "m/z...
PMC9429973	Overall outcomes are excellent with intensive regimens, consolidated with or followed by ibrutinib; however, there are treatment-related toxicities emphasising the need for a tailored approach.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11795610	Some studies have demonstrated that selective activation of TRPV4 in mice was able to accelerate skin barrier regeneration, while knockout of TRPV4 resulted in impaired skin barrier and abnormal differentiation in AD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9622879	Moreover, local energy trading was not supported in this community.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "local", "energy", "trading", "was", "not", "supported", "in", "this"...
PMC7504302	High-throughput RNAi and CRISPR screens provide a tremendous opportunity for the systematic characterization of cancer dependencies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "High-throughput", "RNAi", "and", "CRISPR", "screens", ...
PMC11564322	In the case of the MEG-A2 cell line, it has been shown that the mTOR protein expression decreases during differentiation into megakaryocytes .	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9318744	These results demonstrate that our ACE2plucC3 cell model can be used to evaluate antiviral drugs and potentially developed for high-throughput screening.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "results", ...
PMC8753818	Flow cytometric cell cycle analysis on asynchronous cells showed that compared with the native CHO-K1 cell line, the CHO-KO cell line had a 10% higher proportion of cells in the G2/M phase and a 3% higher proportion of cells in the G0/G1 phase (Fig. 2).Fig.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "...
PMC11676674	Statistical analysis was performed using GraphPad Prism Ver.7.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "analysis", "was", "performed", "using", "GraphPad", "Prism", "Ver.7", "." ] } ]
PMC8524093	Pregnant IFN-α/βR mice at 16–18 days of gestation were infected with 20 pfu of CHIKV via the intradermal route.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Pregnant", "IFN-α/βR", "mice", "a...
PMC11347429	The main responses for up-regulated genes encompass interferon-stimulated genes and chemokine/cytokines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "main", "responses", "for", "up-regulated", "genes", "encompass", "interferon-stimulated", ...
PMC11295144	Our results indicate that the intracellular TM3-4 loop of the γ2 subunits is required for the cooperativity between GABAARs and NL2 in synaptic formation but also for the association between GABAARs and NL2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11637284	In a next step we zoomed into the putative TAC60 and p166 interacting region of T. brucei and compared it with other Kinetoplastid species.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11594588	In the inactive state, GDP is bound to the α subunit.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "inactive", "state", ",", "GDP", "is", "bound", "to", "the", ...
PMC11700247	CD45.2/CD3/CD45.1 T-cell infiltration in irradiated and abscopal tumor representing CART-19 cells. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CD45.2/CD3/CD45.1", "T-cell", "infiltration", "in", "irradiated", "and", "abscopal", "...
PMC9429973	Ocular findings were consistent with known epithelial keratopathy of ADCs and were generally low grade and resolved to ≤ Grade 1 with dose interruptions and/or reductions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11530949	These bimetallic NPs' constituent metals have synergistic effects that enhance their biological properties, including antibacterial, optical, catalytic, electrical, thermal, and magnetic properties (26, 27).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11534377	Furthermore, to minimize the occurrence of false positives, we implemented the Benjamini-Hochberg procedure, a well-established method for controlling the false discovery rate (FDR).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11787651	Now, a packet of fragment ions is collected and pulsed into the accelerator so that they are uniformly received in the accelerator prior to MS analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11087301	This study introduces catulin as a potential linker between pathways leading to breast cancer cell invasiveness which interacts with different CSC and cell adherent molecules .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11721064	In addition, due to the possibility of early transdifferentiation, a portion of the progenitor cell population may be transforming into CK12 positive cells (Additional file 1: Fig. S3D).Further enrichment analysis indicated that corneal cell clusters were primarily enriched in pathways, including IL6/JAK/STAT3, PI3K/AKT/mTOR, and Notch signaling (Fig. 5B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11591794	It was centrifuged sequentially at 12,000× g for 30 s. RNAs were loaded onto the column and centrifuged first with washing solution 1, then twice with washing solution 2, at 12,000× g for 30 s at each stage.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9341513	A more focused view of chromatin interactions at gene promoters is shown in simulated 4C interaction profiles (Fig. 2C; we take a 1-kbp region immediately upstream of a gene's transcription start site [TSS] to be its promoter).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10507284	The meta‐analysis of TROAP prognostic value was based on TCGA, TARGET, GSE21050, GSE30929, and GSE71118 (n = 1109).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11496728	Gene sequence optimization can adjust the GC content of genes, prevent base repeats, eliminate restriction endonuclease recognition sites, and avoid similarities to important RNA motifs located in open-reading frames, as they may cause ribosomal pause that interferes with mRNA processing and translation, apart from factors such as CpG content and TATA cassette.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11345828	C. Overlay of 9 (green) and 18 (cyan) with Mcl-1 protein, π-stacking interaction with R263 (magenta) and hydrogen bonding interaction with N260 (magenta).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11536589	These inhibitors have now been approved by the FDA (Huang et al. 2021; Ou et al. 2022).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "inhibitors", "have"...
PMC11697065	Overall, we conclude that heterogeneity even among related clones represents a confounding effect that obscures biological signatures associated with high productivity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overall", ",...
PMC4277423	Furthermore, individuals with a homozygous CCR5Δ32 deletion are highly resistant to HIV-1 infection –. As a result, CCR5 has been one of major targets for drug and genetic intervention against HIV-1 infection .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5311252	Spectra were then searched using MSGF+ (v10072) and Percolator (v2.08), where eight subsequent search results were grouped for Percolator target/decoy analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC3888431	Recent studies have shown that a combination of de novo and reference-based strategies yields the best outcome for transcriptome assemblies .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Recent", "studies", "have", ...
PMC11679326	Proteins with oligomannose glycans are then transported to the Golgi apparatus, where the α1,2-mannosidases are used to trim the α1,2-linked mannose residues, resulting in the formation of mannopentose glycans (Figure 1a).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	All patients will receive standard premedication before each injection with antihistamine, corticosteroid (methylprednisolone or equivalent) and paracetamol.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "patients", "will", ...
PMC11774747	Fourteen patients with r/r Hodgkin’s lymphoma were treated using escalating doses of CD30.CAR-EBVSTs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fourteen", "patients", "with", "r/r", "Hodgkin", "’s", "lymphoma", ...
PMC9429973	Additional publicly available mRNA-seq data (n = 1,160) were used for quality control modelling.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additional", "publicly", "available", "mRNA-seq", "data", ...
PMC11700165	Recently, a second patient was documented.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Recently", ",", "a", "second", "patient", "was", "documented", "." ] } ]
PMC11750712	The surface assay follows a lyse wash protocol, for each sample a fluorescence-minus-one control was generated to determine CAR positivity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "surface", ...
PMC11470999	However, knockdown of VHL rescued PF‐induced CIP2A downregulation (Figure 6B,C), indicating that PF likely mediates CIP2A degradation through VHL.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10125312	Identifying potential obstacles at the in vitro level of development, such as toxicity to nontarget organs either from the nanomaterial or from light treatment, allows for changes and refinement of the technique without the need for large cohorts of animals.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11679892	This supports the anticancer potential of the extract.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "supports", "the", "anticancer", "potential", "of", "the", "extract", "." ] } ]
PMC10759659	Images were visualized using chemiluminescent horseradish peroxidase substrate (WBKLS0100; Merck Millipore) on Bio-Rad Gel Doc 2000 system analysis software (Bio-Rad Laboratories, Inc., Hercules, CA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11577421	BSA, fluorescein isothiocyanate (FITC), FBS, ethylenediamine, citraconic anhydride, MTT reagent, MTX, Ham’s F-12 culture medium, and DMEM culture medium were from Sigma-Aldrich (Brazil).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11389534	It has been demonstrated that UFSP2 is the main ‘deUFMylation’ enzyme compared with the inactive UFSP1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "has", "been", "demonstrated", "t...
PMC11391695	Preparation of compounds comprising SK-Hep-1 cell vesicles and PEI nanoparticle complexes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Preparation", "of", "compounds", "comprising", "SK-Hep-1", "cell", "vesicles", "and", "PEI"...
PMC10380508	Among these subtypes, kidney renal clear cell carcinoma (KIRC), kidney renal papillary cell carcinoma (KIRP), and kidney chromophobe carcinoma (KICH) are the most common.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11548041	Nanovesicles can be functionalized with aptamers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Nanovesicles", "can", "be", "functionalized", "with", "aptamers", "." ] } ]
PMC4270159	All data obtained from the experiment—raw data, data analysis, control data and quality control data—will be made publicly available, either in the published manuscript or as an open access dataset available on the Open Science Framework (https://osf.io/h0pnz/).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10919056	Differential expression of GJA5 in ccRCC in the GEO database. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Differential", "expression", "of", "GJA5", "in", "ccRCC", "in", "the", "GEO", "databa...
PMC10452486	The genes encoding the heavy chains of these two classes of HLA are closely linked to each other on the short arm of chromosome 6, whereas the gene that encodes B2m is on chromosome 15.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9672323	Furthermore, while dexamethasone reduced the proliferation of PBMCs, piroxicam had no adverse effect on the proliferation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "while", "dexamethasone",...
PMC11519567	I Quantification of SS18-EGFP and SS18-SSX-EGFP in FRAP experiments in (H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "I", "Quantification", "of", "SS18-EGFP", "and", "SS18-SSX-EGFP", "in", "FRA...
PMC11806182	F Heatmap depicting the relationship between four co-expression modules and miR-424.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "F", "Heatmap", "depicting", "the", "relationship", "between", "four", "co-expression", "mod...
PMC6771295	Representative western blot is shown.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Representative", "western", "blot", "is", "shown", "." ] } ]
PMC10938336	Docked complexes of CASP3 protein along with their strongest binding compounds.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Docked", "complexes", "of", "CASP3", "protein", "along", "with", "their", "strongest", ...
PMC11739484	Correlation analyses, including Spearman’s rank or Pearson’s correlation coefficient, were applied for associations between MMP expression and clinicopathological or immune-modulator variables.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11726848	However, it should be noted that dose-rate effects are not entirely straightforward, e.g., there are variations in dose-rate susceptibility among different tumors .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11680578	< 0.001 as compared to that of the RGZ alone.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "<", "0.001", "as", "compared", "to", "that", "of", "the", "RGZ", "alone", "." ] } ]
PMC6771295	The specific primary antibodies for β-Actin (Abcam), Beclin-1 (Cell Signaling), LC3 (Cell Signaling), SIRT1 (B-7, Santa Cruz Biotechnology), SIRT3 (C73E3, Cell Signaling), SIRT5 (D5E11, Cell Signaling), and anti-Flag M2 (Sigma Aldrich) were diluted 1:2,000 in 5% skimmed milk in Tris-buffered saline-Tween (TBS-T).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9046263	HERV elements are identifiable by the presence of established retroviral genes: gag (core structural proteins), pol (viral replication enzymes including reverse transcriptase), pro (viral protease), env (envelope protein) and LTR (Long Terminal Repeats).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8469018	Then, the stained cells were centrifuged at 400× g for 5 min and washed twice with PBS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "the", "stained", ...
PMC11759543	In this study, we combined vorinostat and doxorubicin for the treatment of bladder cancer in both in vitro and in vivo.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this",...
PMC3019555	Immunoblot of HIF-1α and actin from MCF7 cells treated as in A and exposed to normoxia (N) or 4-h hypoxia to visualize HIF-1α protein.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Remarkably, IgHV1-69 was the most prevalent IgHV subgroup in Kazakhstan U-CLL patients (40%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Remarkably", ",", "IgHV1", "-", ...
PMC11487720	In this study, we aimed to uncover a novel aspect of cell death mechanisms by investigating the interaction and relocation of WWOX and TRAF2 under UV/cold shock exposure.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Between November 2021 and February 2022, 472 downloads were documented on one of four platforms.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Between", "November", "2021", "and", "February", "2022...
PMC9429973	Summary/Conclusion: Our findings show the independed prognostic value of TP53 pathogenic variants in pediatric B-NHL patients treated with rituximab-based reduced-intensity therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Summary/Conclusion...
PMC9429973	At the time of assessment (median 4.8 months after the 2 vaccine) anti-spike antibodies were detected in only 42% (N = 29) of patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10125312	In another work, Xia et al. studied the cytotoxicity and uptake of AuNS in hepatic cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "another", "work", ",", "Xia", ...
PMC10094992	MPM is a highly complex tumour, not only to treat but also to understand, due to the involvement of different players in the tumour organization and in the principal pro-tumoural functions .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11700165	SYK comprises N-terminal, tandem SRC homology 2 (SH2) domains connected via the linker-A region, while the linker-B region joins them with the C-terminal kinase domain.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9268183	Other pharmacological activities, such as antioxidant capacity by scavenging reactive oxygen, are important in preventing potential damage to cellular components such as DNA, proteins and lipids.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10654497	Recent studies have shown that ferroptosis is closely related to the pathophysiological mechanisms of various diseases, including cancer, diseases of the nervous system, kidney damage, ischemia-reperfusion injury, and blood disorders.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11617590	Statistical significance was based on the difference compared with 0 μM SFN by two‐way analysis of variance (ANOVA), followed by the Bonferroni test (n = 3) (p < 0.01, *p < 0.001).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11714165	The nanoparticles demonstrate the ability to effectively suppress both osteoclast differentiation and tumor cell growth by inhibiting the NF‐κB signaling pathway, thereby disrupting the vicious cycle in the osteosarcoma microenvironment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10443665	It has been reported that GT from different species of Astragalus consists of 2 fractions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "has", "been", "reported", "that", "GT", "from", ...
PMC11743975	For cells only transfected with Tom20-CIBN-GFP, the GFP-labeled mitochondria rarely changed before and after 60 min of blue light illumination (Figure 2A, Supplementary Video S1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: Given the crucial role for γc cytokines in the development and function of lymphocytes, modulating their activities may offer therapeutic potential in a range of immune-mediated diseases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The AFVI exhibited spontaneous reversal over several years after discontinuation of ineffective combination immunosuppressive therapies and subsequently a successful pregnancy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "AFVI", "exhibited", ...
PMC11604768	Resulting TRE unit sequences were compared to the expected sequences using Starcode.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Resulting", "TRE", "unit", "sequences", "were", "compared", "to", "the", "expect...
PMC11224020	cPLA2 is in gray, and nuclei are in red; scale bar, 10 µm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "cPLA2", "is", "in", "gray", ",", "and", "nuclei"...
PMC9429973	The type of the immunosuppressive regimen is the most important reason of decreased CMV-specific CD8+ immune response following allo-HSCT.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "type", "of", "t...
PMC10955424	Therefore, we analyzed the ascites unique tumor microenvironment to investigate platinum chemoresistance and potential measures to overcome it.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "we", "analyzed"...
PMC11587606	When Dox was withdrawn and the cell cultures maintained for another 96 h (Dox±), RHBDF1 protein levels decreased substantially, while that of E-cadherin, Occludin and ZO-1 protein levels were restored to levels similar to those under Dox-off conditions (Fig. 1F).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11359735	Red bars indicate the means of each group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Red", "bars", "indicate", "the", "means", "of", "each", "group", "." ] } ]
PMC9429973	Firstly, by describing the major differences in interactions between the amino acids in the vicinity of the mutation spot.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Firstly", ",", "by", "...

PMC10955424

Consequently, inhibition of FASN in cisplatin resistance OC cells resulted in resistance mitigation .

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PMC11271278

Although several of the identified oncogenes such as MYC, ETV1, and CCND1 have been previously linked to enhancer hijacking, we identified their novel hijacked enhancers that are cancer type specific.

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PMC11435360

Moreover, VEGF cells were further reduced in the BBN PAG + GEM group compared to the BBN PAG group (p < 0.05, Figure 4E).

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PMC9688728

After thawing, the cells were cultured in DMEM/F12 supplemented with 10% fetal bovine serum and 100 units/mL penicillin/streptomycin (all from Gibco, Waltham, MA, USA) in a humidified CO2-incubator under standard conditions (5% CO2, 37 °C, 100% humidity).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

GFI1B aberrations are linked to inherited bleeding disorders, resulting in macro-thrombocytopenia, gray platelets and increased expression of CD34.

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PMC8956657

Firefly luciferase values were normalized to Renilla luciferase values.

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PMC10831439

The cytotoxicity of the effector cells was assessed in three technical replicates.

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PMC10926885

To forecast miRNAs upstream of NDE1, we collected data from miRDB, miRWalk, miRabel and TrgetScan.

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PMC9429973

For patients with a HES-related hospitalization, the mean (SD) length of stay (LoS) was 11.0 (9.4) days.

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PMC9429973

Moreover, for the first time, we established AITL patient-derived organoid models that can be stablely cultured in vitro.

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PMC7171147

GAPDH was used as a loading control.

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PMC11011837

This opens the possibility of designing experiments to directly verify and confirm the obtained results in patients.

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PMC11052306

In this review article, we present an overview of the use of a particular Schiff base, namely pyridine–imine, linked to the surface of dendrimers, suitable for complexing copper, and the use of such dendrimer complexes in biology, in particular against cancers.

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PMC9429973

While TNF-α 238 GA, AA, and GG account for (54.5, 39.5, and 6% respectively).

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PMC5173112

In current study, we showed that USP21 binds to the promoter region of IL-8 gene and regulates its transcriptional activity.

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PMC9545474

HRMS‐ESI: calculated [M+H] 910.92807 m/z, found 910.92698 m/z. [(

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PMC9429973

Overall outcomes are excellent with intensive regimens, consolidated with or followed by ibrutinib; however, there are treatment-related toxicities emphasising the need for a tailored approach.

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PMC11795610

Some studies have demonstrated that selective activation of TRPV4 in mice was able to accelerate skin barrier regeneration, while knockout of TRPV4 resulted in impaired skin barrier and abnormal differentiation in AD.

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PMC9622879

Moreover, local energy trading was not supported in this community.

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PMC7504302

High-throughput RNAi and CRISPR screens provide a tremendous opportunity for the systematic characterization of cancer dependencies.

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PMC11564322

In the case of the MEG-A2 cell line, it has been shown that the mTOR protein expression decreases during differentiation into megakaryocytes .

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PMC9318744

These results demonstrate that our ACE2plucC3 cell model can be used to evaluate antiviral drugs and potentially developed for high-throughput screening.

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PMC8753818

Flow cytometric cell cycle analysis on asynchronous cells showed that compared with the native CHO-K1 cell line, the CHO-KO cell line had a 10% higher proportion of cells in the G2/M phase and a 3% higher proportion of cells in the G0/G1 phase (Fig. 2).Fig.

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PMC11676674

Statistical analysis was performed using GraphPad Prism Ver.7.

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PMC8524093

Pregnant IFN-α/βR mice at 16–18 days of gestation were infected with 20 pfu of CHIKV via the intradermal route.

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PMC11347429

The main responses for up-regulated genes encompass interferon-stimulated genes and chemokine/cytokines.

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PMC11295144

Our results indicate that the intracellular TM3-4 loop of the γ2 subunits is required for the cooperativity between GABAARs and NL2 in synaptic formation but also for the association between GABAARs and NL2.

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PMC11637284

In a next step we zoomed into the putative TAC60 and p166 interacting region of T. brucei and compared it with other Kinetoplastid species.

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PMC11594588

In the inactive state, GDP is bound to the α subunit.

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PMC11700247

CD45.2/CD3/CD45.1 T-cell infiltration in irradiated and abscopal tumor representing CART-19 cells. (

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PMC9429973

Ocular findings were consistent with known epithelial keratopathy of ADCs and were generally low grade and resolved to ≤ Grade 1 with dose interruptions and/or reductions.

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PMC11530949

These bimetallic NPs' constituent metals have synergistic effects that enhance their biological properties, including antibacterial, optical, catalytic, electrical, thermal, and magnetic properties (26, 27).

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PMC11534377

Furthermore, to minimize the occurrence of false positives, we implemented the Benjamini-Hochberg procedure, a well-established method for controlling the false discovery rate (FDR).

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PMC11787651

Now, a packet of fragment ions is collected and pulsed into the accelerator so that they are uniformly received in the accelerator prior to MS analysis.

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PMC11087301

This study introduces catulin as a potential linker between pathways leading to breast cancer cell invasiveness which interacts with different CSC and cell adherent molecules .

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PMC11721064

In addition, due to the possibility of early transdifferentiation, a portion of the progenitor cell population may be transforming into CK12 positive cells (Additional file 1: Fig. S3D).Further enrichment analysis indicated that corneal cell clusters were primarily enriched in pathways, including IL6/JAK/STAT3, PI3K/AKT/mTOR, and Notch signaling (Fig. 5B).

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PMC11591794

It was centrifuged sequentially at 12,000× g for 30 s. RNAs were loaded onto the column and centrifuged first with washing solution 1, then twice with washing solution 2, at 12,000× g for 30 s at each stage.

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PMC9341513

A more focused view of chromatin interactions at gene promoters is shown in simulated 4C interaction profiles (Fig. 2C; we take a 1-kbp region immediately upstream of a gene's transcription start site [TSS] to be its promoter).

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PMC10507284

The meta‐analysis of TROAP prognostic value was based on TCGA, TARGET, GSE21050, GSE30929, and GSE71118 (n = 1109).

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PMC11496728

Gene sequence optimization can adjust the GC content of genes, prevent base repeats, eliminate restriction endonuclease recognition sites, and avoid similarities to important RNA motifs located in open-reading frames, as they may cause ribosomal pause that interferes with mRNA processing and translation, apart from factors such as CpG content and TATA cassette.

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PMC11345828

C. Overlay of 9 (green) and 18 (cyan) with Mcl-1 protein, π-stacking interaction with R263 (magenta) and hydrogen bonding interaction with N260 (magenta).

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PMC11536589

These inhibitors have now been approved by the FDA (Huang et al. 2021; Ou et al. 2022).

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PMC11697065

Overall, we conclude that heterogeneity even among related clones represents a confounding effect that obscures biological signatures associated with high productivity.

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PMC4277423

Furthermore, individuals with a homozygous CCR5Δ32 deletion are highly resistant to HIV-1 infection –. As a result, CCR5 has been one of major targets for drug and genetic intervention against HIV-1 infection .

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PMC5311252

Spectra were then searched using MSGF+ (v10072) and Percolator (v2.08), where eight subsequent search results were grouped for Percolator target/decoy analysis.

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PMC3888431

Recent studies have shown that a combination of de novo and reference-based strategies yields the best outcome for transcriptome assemblies .

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PMC11679326

Proteins with oligomannose glycans are then transported to the Golgi apparatus, where the α1,2-mannosidases are used to trim the α1,2-linked mannose residues, resulting in the formation of mannopentose glycans (Figure 1a).

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PMC9429973

All patients will receive standard premedication before each injection with antihistamine, corticosteroid (methylprednisolone or equivalent) and paracetamol.

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PMC11774747

Fourteen patients with r/r Hodgkin’s lymphoma were treated using escalating doses of CD30.CAR-EBVSTs.

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PMC9429973

Additional publicly available mRNA-seq data (n = 1,160) were used for quality control modelling.

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PMC11700165

Recently, a second patient was documented.

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PMC11750712

The surface assay follows a lyse wash protocol, for each sample a fluorescence-minus-one control was generated to determine CAR positivity.

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PMC11470999

However, knockdown of VHL rescued PF‐induced CIP2A downregulation (Figure 6B,C), indicating that PF likely mediates CIP2A degradation through VHL.

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PMC10125312

Identifying potential obstacles at the in vitro level of development, such as toxicity to nontarget organs either from the nanomaterial or from light treatment, allows for changes and refinement of the technique without the need for large cohorts of animals.

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PMC11679892

This supports the anticancer potential of the extract.

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PMC10759659

Images were visualized using chemiluminescent horseradish peroxidase substrate (WBKLS0100; Merck Millipore) on Bio-Rad Gel Doc 2000 system analysis software (Bio-Rad Laboratories, Inc., Hercules, CA).

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PMC11577421

BSA, fluorescein isothiocyanate (FITC), FBS, ethylenediamine, citraconic anhydride, MTT reagent, MTX, Ham’s F-12 culture medium, and DMEM culture medium were from Sigma-Aldrich (Brazil).

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PMC11389534

It has been demonstrated that UFSP2 is the main ‘deUFMylation’ enzyme compared with the inactive UFSP1.

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PMC11391695

Preparation of compounds comprising SK-Hep-1 cell vesicles and PEI nanoparticle complexes.

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PMC10380508

Among these subtypes, kidney renal clear cell carcinoma (KIRC), kidney renal papillary cell carcinoma (KIRP), and kidney chromophobe carcinoma (KICH) are the most common.

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PMC11548041

Nanovesicles can be functionalized with aptamers.

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PMC4270159

All data obtained from the experiment—raw data, data analysis, control data and quality control data—will be made publicly available, either in the published manuscript or as an open access dataset available on the Open Science Framework (https://osf.io/h0pnz/).

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PMC10919056

Differential expression of GJA5 in ccRCC in the GEO database. (

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PMC10452486

The genes encoding the heavy chains of these two classes of HLA are closely linked to each other on the short arm of chromosome 6, whereas the gene that encodes B2m is on chromosome 15.

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PMC9672323

Furthermore, while dexamethasone reduced the proliferation of PBMCs, piroxicam had no adverse effect on the proliferation.

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PMC11519567

I Quantification of SS18-EGFP and SS18-SSX-EGFP in FRAP experiments in (H).

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PMC11806182

F Heatmap depicting the relationship between four co-expression modules and miR-424.

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PMC6771295

Representative western blot is shown.

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PMC10938336

Docked complexes of CASP3 protein along with their strongest binding compounds.

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PMC11739484

Correlation analyses, including Spearman’s rank or Pearson’s correlation coefficient, were applied for associations between MMP expression and clinicopathological or immune-modulator variables.

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PMC11726848

However, it should be noted that dose-rate effects are not entirely straightforward, e.g., there are variations in dose-rate susceptibility among different tumors .

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PMC11680578

< 0.001 as compared to that of the RGZ alone.

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PMC6771295

The specific primary antibodies for β-Actin (Abcam), Beclin-1 (Cell Signaling), LC3 (Cell Signaling), SIRT1 (B-7, Santa Cruz Biotechnology), SIRT3 (C73E3, Cell Signaling), SIRT5 (D5E11, Cell Signaling), and anti-Flag M2 (Sigma Aldrich) were diluted 1:2,000 in 5% skimmed milk in Tris-buffered saline-Tween (TBS-T).

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PMC9046263

HERV elements are identifiable by the presence of established retroviral genes: gag (core structural proteins), pol (viral replication enzymes including reverse transcriptase), pro (viral protease), env (envelope protein) and LTR (Long Terminal Repeats).

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PMC8469018

Then, the stained cells were centrifuged at 400× g for 5 min and washed twice with PBS.

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PMC11759543

In this study, we combined vorinostat and doxorubicin for the treatment of bladder cancer in both in vitro and in vivo.

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PMC3019555

Immunoblot of HIF-1α and actin from MCF7 cells treated as in A and exposed to normoxia (N) or 4-h hypoxia to visualize HIF-1α protein.

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PMC9429973

Remarkably, IgHV1-69 was the most prevalent IgHV subgroup in Kazakhstan U-CLL patients (40%).

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PMC11487720

In this study, we aimed to uncover a novel aspect of cell death mechanisms by investigating the interaction and relocation of WWOX and TRAF2 under UV/cold shock exposure.

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PMC9429973

Between November 2021 and February 2022, 472 downloads were documented on one of four platforms.

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PMC9429973

Summary/Conclusion: Our findings show the independed prognostic value of TP53 pathogenic variants in pediatric B-NHL patients treated with rituximab-based reduced-intensity therapy.

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PMC9429973

At the time of assessment (median 4.8 months after the 2 vaccine) anti-spike antibodies were detected in only 42% (N = 29) of patients.

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PMC10125312

In another work, Xia et al. studied the cytotoxicity and uptake of AuNS in hepatic cell lines.

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PMC10094992

MPM is a highly complex tumour, not only to treat but also to understand, due to the involvement of different players in the tumour organization and in the principal pro-tumoural functions .

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PMC11700165

SYK comprises N-terminal, tandem SRC homology 2 (SH2) domains connected via the linker-A region, while the linker-B region joins them with the C-terminal kinase domain.

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PMC9268183

Other pharmacological activities, such as antioxidant capacity by scavenging reactive oxygen, are important in preventing potential damage to cellular components such as DNA, proteins and lipids.

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PMC10654497

Recent studies have shown that ferroptosis is closely related to the pathophysiological mechanisms of various diseases, including cancer, diseases of the nervous system, kidney damage, ischemia-reperfusion injury, and blood disorders.

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PMC11617590

Statistical significance was based on the difference compared with 0 μM SFN by two‐way analysis of variance (ANOVA), followed by the Bonferroni test (n = 3) (**p < 0.01, ***p < 0.001).

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PMC11714165

The nanoparticles demonstrate the ability to effectively suppress both osteoclast differentiation and tumor cell growth by inhibiting the NF‐κB signaling pathway, thereby disrupting the vicious cycle in the osteosarcoma microenvironment.

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PMC10443665

It has been reported that GT from different species of Astragalus consists of 2 fractions.

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PMC11743975

For cells only transfected with Tom20-CIBN-GFP, the GFP-labeled mitochondria rarely changed before and after 60 min of blue light illumination (Figure 2A, Supplementary Video S1).

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PMC9429973

Aims: Given the crucial role for γc cytokines in the development and function of lymphocytes, modulating their activities may offer therapeutic potential in a range of immune-mediated diseases.

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PMC9429973

The AFVI exhibited spontaneous reversal over several years after discontinuation of ineffective combination immunosuppressive therapies and subsequently a successful pregnancy.

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PMC11604768

Resulting TRE unit sequences were compared to the expected sequences using Starcode.

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PMC11224020

cPLA2 is in gray, and nuclei are in red; scale bar, 10 µm.

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PMC9429973

The type of the immunosuppressive regimen is the most important reason of decreased CMV-specific CD8+ immune response following allo-HSCT.

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PMC10955424

Therefore, we analyzed the ascites unique tumor microenvironment to investigate platinum chemoresistance and potential measures to overcome it.

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PMC11587606

When Dox was withdrawn and the cell cultures maintained for another 96 h (Dox±), RHBDF1 protein levels decreased substantially, while that of E-cadherin, Occludin and ZO-1 protein levels were restored to levels similar to those under Dox-off conditions (Fig. 1F).

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PMC11359735

Red bars indicate the means of each group.

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PMC9429973

Firstly, by describing the major differences in interactions between the amino acids in the vicinity of the mutation spot.

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