PMCID string | Sentences string | ner list |
|---|---|---|
PMC9429973 | Aims: Our objectives were to investigate the immune micro-environment of bone marrow (BM) trephine biopsies from patients with high risk MDS and whether elements of the adaptive immunity predict response to 5-Azacitidine (5-AZA) treatment. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11653533 | 2Distribution of Ficus species throughout the world. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"2Distribution",
"of",
"Ficus",
"species",
"throughout",
"the",
"world",
"."
]
}
] |
PMC9429973 | Aims: Determine the role of TP53 in JAK2V617F induced genetic and phenotypic modifications. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"Aims",
":",
"Determine",
"the",
"role",
"of",
"TP53",
"in",
... |
PMC5311252 | It is tempting to speculate that targeting the entire oncomotif-miRNA group by tiny locked nucleic acids could be an efficient way of re-establishing the G1/S checkpoint in cancers with high expression of oncomotif-miRNAs. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11765243 | The minigene was designed so that in the absence of Cre, the WT form of p110α was expressed from the targeted allele. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"The",
... |
PMC11734514 | To assess A549 cells ability in wound healing, a scratch-wound assay was performed on cells treated with 10 µg/mL C. aerizusa extract.8 Cells were seeded in 6-well plates and incubated until 80% confluence. | [
{
"tags": [
"O",
"O",
"B-CellLine",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC9841531 | Compound 24 (5 μM) increased the percentage of total apoptotic cells by a factor of 13 from 0.51 to 6.68% when compared to the untreated A-549 cells, indicating that 24 exhibited cytotoxicity against the A-549 cancer cell line via inducing apoptosis. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC10178190 | After 24 h, the medium was replaced with medium containing 1 mM dexamethasone (Dex), 5 mg/mL insulin, and 0.5 M 3-isobutyl-1-methylxanthine (IMBx). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11686380 | Single-nucleus RNA sequencing data from the human middle temporal gyrus revealed that GAP43 was co-expressed with SLC17A7, a marker of glutamatergic excitatory neurons, in the intratelencephalic, extratelencephalic and corticothalamic neurons of the cortex (Fig. 1E). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11082662 | In our study, ACER2 knockdown led to a downregulation of SMPDL3B protein, while conversely, overexpression of SMPDL3B alleviated the inhibitory effects of ACER2 (Figure 6A; P<0.05). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11806106 | For the measurement of receptor-arrestin interaction, cells were transfected with 0.5 µg MOR-nLuc, 5 µg sYFP-Arrestin3, and 0.5 µg GRK2 (200 ng DNA/well). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC9429973 | Aims: we aimed to study the rare hematological adverse events follwoing the COVID vaccination Methods: Here we are reporting six cases presented to our institute following COVID vaccination within 4 weeks following vaccination, data were retrieved from MRD and events and outcomes were tabulated. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11786156 | In all cases, the mean extravascular Ki-67 index (80.3 ± 17.1%) was significantly higher than the mean intravascular Ki-67 index (68.1 ± 24.6%) (P = 0.012, corrected P = 0.036, Student’s t-test with Holm correction) (Table 2). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC5673955 | The main components of telomerase are hTR (human telomerase RNA), comprising RNA template for synthesis of telomeres, and hTERT (human telomerase reverse transcriptase) which possesses reverse transcription activity and synthesizes the telomeric repeats on the hTR template 1. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC10158546 | pCDH813A includes a GFP fluorescent reporter protein and a resistance marker to the antibiotic puromycin. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"pCDH813A",
"includes",
"a",
"GFP",
"fluorescent",
"reporter",
... |
PMC11682525 | These findings underscore the importance of hypoxic preconditioning and warrant further research into the underlying mechanisms, bringing us closer to effective neurological disorder treatments. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tok... |
PMC9429973 | An overall response rate (ORR) of 62.0% in pts with no prior anti-BCMA treatment (tx) was previously reported in a pooled analysis from phase 1 and phase 2 cohort A at a median follow-up of 7.8 mo. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11366496 | Following the random categorization into distinct cohorts, a cohort of female BALB/c nude mice aged 6–8 weeks underwent anesthesia with three mice in each cohort. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"B-CellLine",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11790599 | After 16 h, the medium containing the transfection mixture was replaced with fresh full medium. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"After",
"16",
"h",
",",
"the",
"medium",
"contai... |
PMC11618052 | An in vitro study evaluated the anti-BRAF efficacy of compounds 8f, 8g, 8h, 8j, and 8l. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"An",
"in",
"vitro... |
PMC11680562 | The experiments successfully synthesized T. dioica dried seeds extract-mediated CuO NPs with an average particle size of 26.44 ± 3.28 nm, displaying a nearly spherical shape as observed through HRTEM. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC10900886 | To investigate whether human immune cell subsets are susceptible to EV-D68 infection, human PBMC were inoculated with EV-D68 strains from subclades A, B2, and A2 (previously known as D). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC6461034 | ○Spin down any remaining liquid sticking to the walls of the peptide solution tube and add that to the peptide/bead mixture. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"○",
"Spin",
... |
PMC11727000 | Statistical calculations were performed using the embedded analysis tools in Prism. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"Statistical",
"calculations",
"were",
"performed",
"using",
"the",
"embedded",
"analysis",
... |
PMC11743975 | Image entropy of both the niclosamide and blue light groups was significantly lower than the niclosamide-treated group (Figure 4B). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"Image",
"entropy",
... |
PMC11064533 | For single nucleotide variation search, the reads obtained for each isolate were mapped against the strain 4972 genome using bwa and called with bcftools (34). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11721064 | The results revealed substantial heterogeneity between cells derived from the two tissue types (Additional file 1: Fig. S3A). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"The",
"results",
... |
PMC11760643 | Finally, it demonstrated that this mAb can mediate CDC in human leukocytes expressing relatively high cell surface P2X7. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"Finally",
",",
"it",
"demonstrate... |
PMC8345486 | Considering the unique physicochemical properties of the metallacarboranes and antimetabolite activity of nucleoside derivatives, we designed and synthesized the adenosine conjugates with metallacarboranes containing iron, cobalt, or chromium as semi-abiotic compounds that influence cisplatin-resistance of cancer cells. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC9429973 | Results: The proportion of mutations and ≥ 2 mutations detected by high throughput sequencing was significantly higher than that by SS (P=0.046). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tok... |
PMC9429973 | In blood cells, relative TMEM244 expression in T cells, both CD4+ (4.7E-04) and CD8+ (6.9E-04) was higher than in any other population of PBMC, including CD19+ B-cells (2.7E-05), CD56+ NK cells (1.2E-04), and CD14+ monocytes (8.8E-05). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC8735881 | In human CD4 T cells, GPI-10E8 and its bifunctional derivatives were capable of fully blocking infections of diverse HIV-1 strains regardless of their tropism and the modified cells displayed a robust selective survival advantage over unmodified cells following HIV-1 infection. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11467800 | K562‐IR cells were continuously cultured with 10 μM imatinib mesylate. | [
{
"tags": [
"B-CellLine",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"K562‐IR",
"cells",
"were",
"continuously",
"cultured",
"with",
"10",
"μM",
"imatinib",
... |
PMC11357960 | On the contrary, the percentage change of other 12 genes had no significant correlation with the prevalence rates of NR ( Supplementary Figures 1, 2 ). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11476666 | Since stemness characteristics are based on the expression of specific markers, such as SOX2 and CD44, their protein levels, both in 2D and 3D cell cultures treated with stilbenes, were evaluated by Western blotting. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC5386478 | We next examined the effect of TGM2-v1 silencing in MSTO-211H spheroids. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"B-CellLine",
"O",
"O"
],
"tokens": [
"We",
"next",
"examined",
"the",
"effect",
"of",
"TGM2-v1",
"silencing",
"in",
... |
PMC11701801 | Data are presented as the mean ± SD; n = 3 independent experiments. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"Data",
"are",
"presented",
"as",
"the",
"mean",
"±",
"SD",
... |
PMC11461833 | Overexpression of HA-Lamin A in the HEK293 cell line increased the lamin A transcript levels. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"B-CellLine",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"Overexpression",
"of",
"HA-Lamin",
"A",
"in",
"the",
... |
PMC11577421 | Liquid chromatography mass spectrometry (LC-MS) experiments were performed in the MSE mode using a Synapt G2 mass spectrometer (Waters) coupled to a nanoAcquity UPLC (Waters). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11537649 | In HCC, miR-152-3p exhibited antineoplastic activity by targeting CDK8. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"In",
"HCC",
",",
"miR-152",
"-",
"3p",
"exhibited",
"antineoplastic",
"activity"... |
PMC11770746 | Oxoplatin, ctc-[Pt(NH3)2(OH)2Cl2], (26.7 mg, 0.08 mmol) was stirred overnight at 30 °C with the activated paclitaxel (100 mg, 0.1 mmol) in 3 mL of DMSO. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11754436 | The expression level of miR-362-5p in MG63 cells was increased after transfection with miR-362-5p mimic, *Represent comparison with the mm group. ( | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"B-CellLine",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC3730428 | Circulating levels of TNFα are elevated in patients with MPM, and these levels are reduced following surgical debulking. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"Circulating",
"levels",
"of",
"TN... |
PMC9429973 | Epcoritamab is a subcutaneously administered, well-tolerated, bispecific antibody with single-agent antitumor activity in relapsed/refractory (R/R) aggressive B-cell non-Hodgkin lymphoma (NHL). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
... |
PMC10040136 | As the immunofluorescence and FACS methods used for MSC counting in this experiment were deficient in terms of accuracy and sample integrity respectively. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"As",
... |
PMC9429973 | Patients in ATG cluster 1, showing higher absolute counts of αβ- and activated T cells compared to cluster 2 were associated to a significantly higher 1-year OS (98% vs. 79%, p=0.0023) due to lower NRM (p=0.032) and relapse (p=0.01). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11718109 | Cells were prefixed with 4% (v/v) PFA in Live Cell Imaging Buffer (Life Technologies) for 15 min followed by three times washing with the same buffer. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC9250505 | All cell lines have been tested for the absence of mycoplasma. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"All",
"cell",
"lines",
"have",
"been",
"tested",
"for",
"the",
"absence",
"of",
... |
PMC8973085 | Anal. | [
{
"tags": [
"O",
"O"
],
"tokens": [
"Anal",
"."
]
}
] |
PMC9429973 | In detail, it was 1.2 (range, 0-4) and 1.5 (range, 0-7) per patient in PPV- and in PET-MF, respectively (p=0.01). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11564322 | Interestingly, no changes in the PPARγ mRNA expression were observed in the K562 cells co-treated with the c-SRC inhibitor I and the VGVAPG peptide, compared to the control. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"B-CellLine",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11718817 | Interestingly, the effects of IL-18R deficiency and activation with nigericin on both parameters were abrogated at the late time point, after 18 h of coculture. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11612626 | Effect of compound A on immunoproteasome subunit β5i /PSMB8 association with the proteasome activator and immunoproteasome. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"Effect",
"of",
"compound",
"A",
"on",
"immunoproteasom... |
PMC11723947 | S1p, q) and co-injected them with the mixture of syngeneic and semi-allogeneic bone marrow. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"S1p",
",",
"q",
")",
"and",
"co-injected",
"them... |
PMC11026382 | d Cumulative distribution of positions in each epistatic cluster by distance to the DHFR active site in the TYMS R166Q background. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"d",
"Cumulative",
... |
PMC11129910 | The fixed cells were then spun down and resuspended in 2 ml of Carnoy's fixative. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"The",
"fixed",
"cells",
"were",
"then",
"spun",
... |
PMC11049548 | Exceptions are the signals of a few molecules, i.e., two UDP-sugars (N-acetyl-glucosamine and N-acetyl-galactosamine, UDP-NAcGln and UDP-NAcGal), which are visible only in the lysates of the immortalized cell lines, and the signals of UDP-glucose (UDP-Glu) and inositol, which are only present in the lysate of HGSOC cells (Figure 1D). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC7812570 | GraphPad Prism 6 software was applied to statistically analyze data. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"GraphPad",
"Prism",
"6",
"software",
"was",
"applied",
"to",
"statistically",
"analyze",
"data",... |
PMC10317042 | For the first time, we identified a transcription factor that regulates EWSR1::ATF1 expression. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"For",
"the",
"first",
"time",
",",
"we",
"identified",
"a",
... |
PMC11718817 | Murine pancreatic ductal adenocarcinoma (PDAC) cell line Panc02 (RRID:CVCL_D627), which was originally derived from a methylcholanthrene-induced pancreatic ductal adenocarcinoma in C57BL/6 mice , was stably transfected to express ovalbumin (OVA) as described before (PancOVA) . | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"B-CellLine",
"O",
"B-CellLine",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"... |
PMC11371747 | We selected cell lines based on their variation in 5FU sensitivity, while we added cell lines which were adapted to grow under low folate concentrations, hence better representing the physiological folate environment (Lemos et al., 2008; Lemos et al., 2009). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC9429973 | starting one week after tumor challenge and continued for 4-8 weekly injections and mice were sacrificed when pre-determined limits of tumor burden were reached. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
... |
PMC11590870 | As for MOPH, this is the first research that reports its effect on cancer cells. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"As",
"for",
"MOPH",
",",
"this",
"is",
"the",
... |
PMC11126803 | ERβ, estrogen receptor β; ERE, estrogen response element; ZEB, zinc finger E-box binding homeobox 1. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"ERβ",
",",
"estrogen",
... |
PMC11734514 | Proteins were extracted from cells using PRO-PREP solution (iNtRON Biotechnology, MA, USA). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"Proteins",
"were",
"extracted",
"from",
"cells",
"usin... |
PMC10178190 | Moreover, OC cell lines obtained from the same patient before and after development of cisplatin resistance demonstrated higher release of IL-6 after the acquisition of resistance. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC3035438 | By plotting the percentage of binding as a function of competitor antigen concentration (Figure 3C), we determined the concentration of competitor required to inhibit 50% of the binding of the free antibody in solution (IC50). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC10093184 | Due to the successful implementation of immune checkpoint inhibitors into the clinical practice in the recent years, immunotherapy for osteosarcoma has attracted attention as a potential treatment modality for this lethal disease . | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC9429973 | Surprisingly, functional studies suggest that consequential effects are enhanced in LNP-SM. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"Surprisingly",
",",
"functional",
"studies",
"suggest",
"that",
"consequential",
"effe... |
PMC6487404 | Evaluation of the viability of the everted gut sacs The viability and any possible damage of the gut was determined by measuring the release of the cytosolic enzyme lactic dehydrogenase (LDH), as an indicator of cell damage, and analyzing the glucose concentrations both in the mucosal and serosal sides (11, 15). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11627133 | While conventional fluorescence microscopy has provided insights into the organization of cellular compartments and tissue composition, SMLM has advanced our understanding of cellular functions and biomolecular interactions to the molecular level. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11064533 | Sequences of DEGs unannotated by PROKKA (n = 148) along with annotated target genes were analyzed by NCBI blastp, Protein Homology/analogy Recognition Engine (Phyre2) (24), bacterial localization prediction tool (PSORTb 3.0) (25), transmembrane topology and signal peptide predictor (Phobius) (26), and Prediction of transmembrane helices in proteins (TMHMM Server v.2.0.) ( | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC8973085 | Anal. | [
{
"tags": [
"O",
"O"
],
"tokens": [
"Anal",
"."
]
}
] |
PMC11122631 | For measuring infrared data, the Jasco FT/IR-4X spectrophotometer was selected. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"For",
"measuring",
"infrared",
"data",
",",
"the",
"Jasco",
"FT/IR-4X",
"spectrophotometer"... |
PMC10440586 | The CD99 expression changes under different treatments. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"The",
"CD99",
"expression",
"changes",
"under",
"different",
"treatments",
"."
]
}
] |
PMC7305184 | To investigate, if this one statistically significant differences between CTRL and EP group is repeatable and not an experimental error we repeated the experiment. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tok... |
PMC4485786 | Expression was normalized to that of human CD45. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"Expression",
"was",
"normalized",
"to",
"that",
"of",
"human",
"CD45",
"."
]
}
] |
PMC11085211 | Nevertheless, we did not observe the cleavage of caspase 3, caspase 9, and PARP-1, suggesting a cell death mechanism other than classical apoptosis. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11019355 | An intriguing open question is the relative roles that cis and trans effects play in gene regulatory divergence across species. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"An",
"intriguing",
"open",
... |
PMC7192625 | To consider a larger number of histone modifications and estimate consistency between results on Hi-Cand PCHi-C networks, we calculated Chas of the six histone marks and ATAC-seq from (33) on the FitHiC network for the lymphoblastoid cell line GM06990 (Supplementary Figure S8B). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC3931643 | We observed a similar increase in sensitivity when the cells were treated with a structurally distinct asTORi, AZD8055, indicating that these results are specific to mTOR inhibition (data not shown). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC9325715 | The SDS-PAGE analysis of obtained complex was performed (Fig. 3). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"The",
"SDS-PAGE",
"analysis",
"of",
"obtained",
"complex",
"was",
"performed",
"... |
PMC9712534 | More specifically, we speculate that TOP2B H58Y should be capable of going through its catalytic cycle from the initial DNA binding step to at least the step of religation of cleaved DNA ends, where etoposide acts. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11723210 | Moreover, this unwrapping process is prone to errors, particularly in areas with large phase gradients or low spatial sampling, due to the absence of reliable initial guesses. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11750696 | In parallel, Treg cells deficient in Hrd1 exhibit heightened IRE1α levels, triggering the MAPK p38 cascade, which hinders Foxp3 synthesis and thus undermines Treg stability (57). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11320834 | Symptoms that already appear are nonspecific and include, for example, abdominal pain, early satiety, or changes in bowel habits . | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"Symptom... |
PMC11457557 | Furthermore, study indicates that early glucose management in people with DM is vital in preventing long-term DVC. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"Furthermore",
",",
"study",
"indicates",
... |
PMC11001582 | Both daw and Mp levels were increased in GR36 flies (Fig. 7a), consistent with both the knock-in mouse and patient iPS cell motor neuron data. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC9429973 | Pre-emptive Rituximab, given to those with EBV reactivation, reduces the risk of PTLD. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"Pre-emptive",
"Rituximab",
",",
"given",
"to",
"those",
"wi... |
PMC11593084 | LN229, LN229/PDPN, and LN319 cells were cultured in Dulbecco’s Modified Eagle’s Medium (DMEM) [Nacalai Tesque, Inc. (Nacalai), Kyoto, Japan]. | [
{
"tags": [
"B-CellLine",
"O",
"B-CellLine",
"O",
"O",
"B-CellLine",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"... |
PMC7342409 | Effect of imatinib on drug sensitivity of GIST882-ir cell line. ( | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"B-CellLine",
"O",
"O",
"O",
"O"
],
"tokens": [
"Effect",
"of",
"imatinib",
"on",
"drug",
"sensitivity",
"of",
"GIST882-ir",
"cell"... |
PMC11285179 | CCL28 was up-regulated in all three lung adenocarcinoma cell lines, whereas others were not (Fig. 1D). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"CCL28",
"was",
"up-regulated",
"i... |
PMC11720808 | ns, no significant difference; *P < 0.05; **P < 0.01 compared with the control group. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"ns",
",",
"no",
... |
PMC7762347 | Cytotoxic effects of CYN and MCLR and their mixtures were assessed after 24 and 72 h of exposure on HepG2 cells. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"B-CellLine",
"O",
"O"
],
"tokens": [
"Cytotoxic",
"e... |
PMC11706776 | Indeed, after KCNN1 silencing, a significant decrease in cell viability was observed in cells treated with 10 nM doxorubicin, whereas no effect was observed in control conditions. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11591038 | These previous findings thus point to the complex, even contradictory, roles of HIF-1 in AD. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"These",
"previous",
"findings",
"thus",
"point",
... |
PMC10631132 | Statistics are based on ANOVA followed by Tukey’s multiple comparison post hoc test (I n = 3 well replicates, J, K n = 50 analyzed cells, **p < 0.01, ***p < 0.001) Morphology assessment of cells following osteoclast differentiation using CLSM. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11547972 | Clonogenic growth is shown in Figure 4. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"Clonogenic",
"growth",
"is",
"shown",
"in",
"Figure",
"4",
"."
]
}
] |
PMC11763111 | E The flow plots illustrate the proportion of CD161 marker expression on the surface of T cells in the peripheral blood of four healthy donors. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tok... |
PMC10506676 | In agreement with our study, Lu et al. stated that in Burkitt's lymphoma, EBNA1 increases the expression of the BIRC5 gene by forming a complex and binding to the promoter of this gene (37). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.