Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
Community
1
PMCID
string
Sentences
string
ner
list
PMC11547972
Of the many available herbal drugs, amygdalin and sulforaphane (SFN) are among the ones purported to exert distinct anti-tumor properties.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Of", ...
PMC9429973
At diagnosis 9 patients (69.2%) presented with high risk disease, 2 with intermediate risk and 2 with low risk disease.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11739670
The specificity of the interaction was further confirmed by the lack of binding of CD8 to HLA‐A2(D227K/T228A) that harbors mutations that prevent specific CD8 contacts (Figure S2C).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
The NR group had more deaths (25 vs 9 pts).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "NR", "group", "had", "more", "deaths", "(", "25", "vs", "9", ...
PMC11297139
f Left: spheroid formation assay performed for four cell lines over 4 days.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "f", "Left", ":", "spheroid", "formation", "assay", "performed", ...
PMC11388384
Estimates from 10 bootstrap replicates plotted in red, and the mean +/− SEM.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Estimates", "from", "10", "bootstrap", "replicates", "plotted", ...
PMC11699042
In synopsis, ranking plots for each different data layer comparing 12 months of continuous culture of each EwS cell line clearly suggest a range of stability that may inform decision-making on which cell line models to preferentially employ in this COTF-driven pediatric cancer (Fig. 2f).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11653168
In conclusion, Stattic exhibited a significant therapeutic potential for T-ALL via a dose-dependent reduction of cell viability, inhibiting STAT3 phosphorylation, and promoting both apoptotic and autophagic cell death; however, further studies are required before clinical application.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11803149
Anti-CD8a (53-6.7, Biolegend), anti-CD44 (IM7, Biolegend), anti-CD62L (MEL-14, Biolegend), anti-PD1 (RMP1-30, Biolegend), anti-Tim3 (RMT3-23, Biolegend), anti-CD45.1 (A20, Biolegend), anti-CD45.2 (104, Biolegend), anti-Tox (TXRX10, e-bioscience), anti-GzmB (GB11, Biolegend), anti-IFN-γ (XMG1.2, Biolegend), anti-Perforin (S16009A, Biolegend), anti-TNFα (MP6-XT22, Biolegend), and anti-Thy1.1 (OX-7, Biolegend) were used.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11687663
All the phytoconstituents showed moderate to good binding affinity ranges from -5.2 to -8.6 kcal/mol (Table 3).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "the", "phytoconstituents", ...
PMC10743717
This rate equation cannot illustrate competitive, noncompetitive or uncompetitive inhibition (see SM2 of Ref. ).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "rate", "equation", "can",...
PMC10978090
Moreover, this strategy allows brief re-exposure to heparin during CBP in the acute phase of HIT without thrombotic complications associated with the use of alternative anticoagulant therapies.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5854676
The first peak lies at 500 cm, which corresponds to MgO. The second significant peak relevant to carbon appears at approximately 1491 cm.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10669128
Moreover, transferring tumor fragments within mice allowed them to establish a novel AS model suitable for preclinical studies and for new therapy development .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11155445
N-((3-Ethylphenyl)carbamothioyl)-4-methylbenzamide (141) synthesized by Ahmed et al. showed strong binding interactions with carbonic anhydrase having a binding energy value of −6.6 kcal mol.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11653533
Fig. 1Some Ficus species and the different plant parts (Plants, 2023).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "1Some", "Ficus", "species", "and", "the", "different", "...
PMC2196094
One additional difference may also lie in the expression pattern for RMCP-5.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "additional", "difference", "may", "also", "lie", "in", "the", "expression...
PMC11661040
The human osteosarcoma cell lines Saos-2, U2OS, 143B, and MG63 were purchased from Procell Life Science and Technology (Wuhan, China).
[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8916024
There was no statistical difference in the gut microbial function between adult and juvenile snails (P > 0.05), which implied that the nutrients required during the growth and development of snails were consistent.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11754291
The observed increase in these protein levels following irradiation suggests direct activation of melanogenic pathways.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "observed", "increase", "in", "these", "protein", "le...
PMC7685376
Each sample was labeled with the corresponding iTRAQ reagents from the 8plex kit according to the manufacturer’s protocol.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "sample", "was", "labeled"...
PMC10759659
ARID1A is the most frequently mutated subunit of the chromatin remodelling complex and the most commonly mutated gene in cancers.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ARID1A", "is", "the", ...
PMC11764090
IbbHLH116 functions like ICE1, conferring cold tolerance to I. batatas (Table 2) .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "IbbHLH116", "functions", "like", "ICE1", ",", "conferring", ...
PMC11615828
The IFT machinery and ciliary axonemes are labeled by FKBP‐IFT88 and FRB‐MAP4m, respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "IFT", "machinery", "and", "ciliary", "axonemes", "ar...
PMC10538569
Infections were performed in triplicate.
[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Infections", "were", "performed", "in", "triplicate", "." ] } ]
PMC11765243
The thymus of p110αKD-T mice had increased cellularity that was mainly due to an enhanced population of the immature thymus CD4CD8 DP population, which makes up the highest proportion in this organ.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11138140
Therefore, cell spreading could be a confounding factor when interpreting raw unnormalized morphology measurements observed between control and treatment conditions and should be accounted for in the experimental design.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9964654
Afterwards, the solutions were diluted and filtered using a 0.20 µm syringe filter.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Afterwards", ",", "the", "solutions", "were", "diluted", "and", ...
PMC11267830
The plot was generated with IGV.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "plot", "was", "generated", "with", "IGV", "." ] } ]
PMC9429973
Image: Summary/Conclusion: This was the largest ruxolitinib real-world study in China.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Image", ":", "Summary/Conclusion", ":", "This", "was", "the", "largest", ...
PMC11155445
Scientists are intrigued by the biological properties exhibited by 1-(acyl/aroyl)-3-(substituted)thiourea derivatives, as evidenced by numerous scholarly articles dedicated to their investigation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scientists", ...
PMC9429973
Monterrey; Hematology, Hospital Civil de Guadalajara “Fray Antonio Alcalde”, Guadalajara; Hematology, UMAE Hospital de Especialidades #71, Torreon; Hematology, Hospital General de México “Dr. Eduardo Liceaga”.;
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11673128
ALK-driven cancers comprise a panel of blood and solid malignancies that are associated with a dismal prognosis, particularly in the relapsed/refractory setting .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ALK-dri...
PMC9429973
Estimated OS-rates after 1 year were 90% in the total population, 93% in the TP53 aberrant population and 90% in the TP53 wt population.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11621493
Subsequently, the medium was changed to DMEM +/+ comprising inhibitors or DMSO as control but containing 300 μM rac-18:1 MAG (M7765, Sigma Aldrich) for 3.5 h. MAG was emulsified in cell culture medium in an ultrasonic bath (30 s) followed by sonication with a Sonopuls ultrasonic homogenizer for 3 × 10 s with an amplitude of 15%.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11626627
Validation of the effects of circATP2B1 and TWIST1 using Western blotting in 786-O cells transfected with pLKO.1+pLVTHM, oe-circATP2B1+pLKO.1, oe-TWIST1+pLVTHM, and oe-circATP2B1+oe-TWIST1. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC10887351
The evidence that, together, cancer and embryo expressed β3-ARs upregulated under hypoxia guided researchers to the hypothesis that β3-ARs over-expression might represent one of the mechanisms by which in origin embryo, and then cancer, adapted their growth in an adverse environment .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5925824
Frozen PBMCs were thawed, cultured in 10% FBS RPMI overnight at 37 °C at 5% CO2, and seeded in a 96-well flat bottom tissue culture plate at 1 × 10 cells per well in 100 μl of 10% FBS/RPMI-1640.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8068766
To identify DEGs between HepG2 and HepG2-2.2.15 cells in the presence or absence of Se, limma package in R was used (Ritchie et al., 2015).
[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10329237
β-catenin, through coupling with CBP (CREB binding protein), is necessary for the transcription of α-SMA in alveolar cells (38).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC8068766
A score called ‘DEG score’ was calculated (Cavga et al., 2019), providing the normalization of the results for each DEG relative to each other.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11429241
However, this cell line formed better 3D cell structures with the spheroid scaffolds.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "this", "cell", "line", "formed", "better", "3D",...
PMC9429973
Proteomics revealed increased levels for proteins involved in FLT3 wildtype signaling in specimens with low in-vitro response to the currently used venetoclax-azacitidine combination.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Proteom...
PMC11764090
Glutathione regulates MPK3 expression through WRKY40 .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Glutathione", "regulates", "MPK3", "expression", "through", "WRKY40", "." ] } ]
PMC10142392
The release of the drugs is thermo-sensitive above the LCST of the PNIPAM chains.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "release", "of", "the", "drugs", "is", "thermo-sensitive", ...
PMC9164404
C Intracellular Pt uptake of the cells treated with various drugs (10 μM Pt) for 1, 4, and 7 h respectively via ICP-MS.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11701801
The SS18-WT protein in Aska-SS shSSX cells (harboring SS18-WT) localized upstream of the TSS of the KREMEN2 locus (Fig. 3D).
[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], ...
PMC8343815
Radiosensitivity induced by gold nanoparticles occurs when the radiation energy is in the megavoltage range, and the Compton effect is the major interaction .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11724582
Differential gene expression analysis, along with GO and KEGG enrichment analyses, was performed to predict the potential mechanisms underlying resistance to third-generation EGFR-TKIs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973
In the multivariate analysis for OS, ELN adverse risk was the strongest predictor (HR 2.09, p<0.001), followed by MRD(+) status (HR 1.68, p<0.001), while treatment intensity and age were not significantly predictive.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
However, the toxicity of chemotherapeutic drugs is still inevitable.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "toxicity", "of", "chemotherapeutic", "drugs", "is", "still", "inevitable"...
PMC11711345
The mixture was centrifuged at 4000 rpm at 15°C for 10 min, after which the supernatant was discarded.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mixture", ...
PMC11670954
The cells were incubated overnight at 4°C with rabbit primary antibodies, against ZO-1 (ab96587, 1:500, Abcam), Occludin (27260-1-AP, 1:500, Proteintech), RhoA (10749-1-AP, 1:500, Proteintech), ROCK2 (20248-1-AP, 1:100, Proteintech, China), and MLCK (21642-1-AP, 1:100, Proteintech).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11119602
The protein–protein docking simulation was performed using the High Ambiguity Driven protein–protein DOCKing (HADDOCK version 2.2) Webserver .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC11694625
Herein, on the basis of preliminary screening of the cytotoxic activity of 3a–3d by MTT assay, 3b and 3c were further investigated for their pro-apoptotic effect, DNA-binding and CDKs inhibitory activities.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8903741
C SDS-PAGE analysis of #6 antibody after (+) or before (–) protein reducing through 100 mM DTT and heating.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973
Results: Infectious complications in the early post-transplant period was noted in 94.6% of MM patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "Infectious", "complications", "in...
PMC11727145
When the DED constructs were maintained in early or late burn wound exudates, the MTT staining results indicated the presence of viable cells, with both conditions showing similar levels of MTT staining intensity, indicating comparable cell viability and proliferation (Figure 6A,B; upper right corner).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Adjusted comparisons to other therapies used in real-world clinical practice (RWCP) help inform the relative efficacy of cilta-cel in TC exposed patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC8414691
The increase was particularly relevant for CM, where the misaligned chromosomes carry the centromere (Additional file 4: Fig. S3), strongly suggesting that they were not lost fragments resulting from chromosome breaks.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11537649
In the present study, we hypothesized that Lnc NEAT1 could serve as a miR-152-3p sponge to facilitate the progression of melanoma by targeting CDK6.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Clinical characteristics data at diagnosis according to HRC are shown in Table 1.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Clinical", "characteristics", "data", "at", "diagnosis", "according", "to", ...
PMC11473750
a Homozygous TH-MYCN (TH-MYCN) mice were screened for delay in tumour development after ENU chemical treatment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "a", "Homozygous", "TH-MYCN", "(", "TH-...
PMC8992508
Beside the compounds described previously, other compounds belonging to different chemical classes have been described, both as BCRP selective modulators and as P-gp/BCRP dual modulators.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11476004
Ribeiro et al. analysed the frequency of genomic instability using the comet assay on lymphocytes in rats with oral squamous cell carcinoma.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ribeiro", "e...
PMC11747885
Another initial hit from the screening was SGI-1027 (1), which exhibited an IC50 value of 3.96 μM for Rlig1-AMP.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Another", "i...
PMC11036064
Our results have shown no statistically significant difference between the expression level of hsa-miR-34a-5p in GBM tissues and normal brain tissues (Figure 3C(Fig.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11351758
CL levels were depleted from 100% down to 68% for IR and 84% for the NEAR and FAR points.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CL", "levels...
PMC11739504
Acetylated-α-tubulin on lysine 40 residue is a cilia marker.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Acetylated-α-tubulin", "on", "lysine", "40", "residue", "is", "a", "cilia", "marker", "." ] } ]
PMC11040965
Wilcoxon signed-rank test To confirm the epigenetic silencing of plasma cell proteasome subunits, we tested the effects of decitabine, an inhibitor of DNA methylases.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9119314
7, 9-Dibromocryptolepine (4): As for 3 above except that up to 4 equivalents of NBS were required for complete reaction.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "7", ...
PMC10565698
We performed Venny analysis (Fig. 4B).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "performed", "Venny", "analysis", "(", "Fig.", "4B", ")", "." ] } ]
PMC6442998
Regulation of expression of differentiation genes in GIST882 and GIST48 cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O" ], "tokens": [ "Regulation", "of", "expression", "of", "differentiation", "genes", "in", "GIST8...
PMC8540611
Viability of cells (relative units—r.u.)
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Viability", "of", "cells", "(", "relative", "units", "—", "r.u", ".", ")" ] } ]
PMC9429973
Greater consensus is needed to avoid unnecessary invasive testing for the diagnosis and follow-up of patients with ITP.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Greater", "consensus", "is", "needed", ...
PMC11585587
Several studies have also explored the combination of RA with other drugs, such as cisplatin, to enhance therapeutic efficacy in human carcinoma.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11742047
Lipid network between the two conditions with node size scaled by -log10 of the q-value in the comparison with Mann–Whitney U test between CBD treated vs control.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8735881
Target cells stably expressing GPI-anchored transgenes were generated as described previously .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Target", "cells", "stably", "expressing", "GPI-anchored", "transgenes", "were", "generated", ...
PMC10907726
To assess the potential of DATS in migration and invasion, we conducted wound healing and transwell experiments.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "assess", "the", "potential", "of...
PMC11732628
Additionally, miR-490-3p overexpression significantly decreased the migration and invasion of the 143B cells (Figure 1D-1G).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ...
PMC8526701
Our findings demonstrated that the expression of BRD9 was upregulated in GIST tissues.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Our", "findings", "demonstrated", "that", "the", "expression", "of", "BRD9"...
PMC9105697
The patient subsequently developed several metastases, one calvarial, as well as bilateral lung lesions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "patient", "subsequently", "developed", "several", ...
PMC10955424
Ascites fluid has been linked clinically to poor prognosis and chemoresistance , therefore the present study monitored the ability of ascites fluids to promote platinum chemoresistance to OC cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Spectra were generated using the MALDI-TOF-MS system.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Spectra", "were", "generated", "using", "the", "MALDI-TOF-MS", "system", "." ] } ]
PMC11093197
It plays a pivotal role in facilitating cell cycle progression through the G1‐S transition by triggering the phosphorylation of RB1 by CDK4/6 and CDK2.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11721295
We assessed lung sections from each group for KRAS expression by Western blotting using a RAS-specific antibody.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "assessed", "lung", "sections", "from", ...
PMC8633974
ACH2, Jlat and U1 cells were stimulated three days following transfection or transduction or LNP treatment with recombinant tumour necrosis factor-alpha (TNFα; 15 or 20 ng / mL) or by phorbol 12-myristate 13-acetate (PMA; 20 ng/mL or 50 nM) in both treated and untreated group.
[ { "tags": [ "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC9429973
These types of lymphoma represent the most common lymphoid malignancies in adults and their incidence rate is still increasing.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "types", "of", "lymphoma"...
PMC11739484
Fig. 9Correlation of MMP7, MMP11, and MMP14 with numerous functional states and expression validation analyses in skin cutaneous melanoma (SKCM) and control cell lines. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Due to the rarety as well as to the fact that at least for AITL and MF/SS median age at diagnosis is greater than 60 years old, there is limited number of reports on allogeneic stem cell transplant outcomes and data from prospective studies are missing Aims: To describe our experience on allogeneic transplant outcomes in a small cohort of relatively young patients with AITL (3), HSTCL (3), MF/SS (8) Methods: Records of 14 patients (6 men, 8 women), who underwent consecutively allogeneic stem cell transplant from 01/01/2008 to 31/12/2019, were retrospectively studied.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11047729
It reduces the level of c-Myc and Sp1 proteins as well as DNA-binding actions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "reduces", "the", "level", "of", "c-Myc", "and", "Sp1", ...
PMC9429973
According to R-IPSS we included 13 (30.2%) Very Low Risk, 11 (25.2%) Low risk and 19 (44.2%) Intermediate patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10047551
Furthermore, we found that in individual patient tumor samples, the PD-L1 mRNA expression levels were not invariably associated with concordant DNA methylation levels, further indicating the significance of factors beyond PD-L1 methylation in regulating PD-L1 expression.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11092418
To date, TMZ is the only drug that has gained FDA approval for treatment for patients with brain cancer, and no HER inhibitors have yet been approved for the treatment of patients with brain cancers.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11707832
For instance, Daila S. Gridley demonstrated that low-dose photons and solar particle events notably upregulated MAN2B1 expression in mouse liver .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "instance", ...
PMC9429973
Mortality rate was higher in LPD group of patients than in GP group (45, 28% vs. 26, 16%) patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973
ORR was 57.9% (22/38; 1 CR, 21 PR/PRL) per iwCLL criteria in the efficacy-evaluable population of pts with CLL/SLL treated at preliminary RP2D.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11562028
The hemolysis rate is calculated by the following formula: At 37 °C, the A498 cells were cultured in 24-well plates at a concentration of 2 × 10 per well for 12 h. A volume of 100 μg mL of the Re-CDs aqueous solution was added at set concentrations.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
An initial use of low dose TKIs, with dose optimization in case of absence of optimal response, is a promising strategy in elderly patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973
Using band 4.2 mice, a well-established model of HS (Peters LL et al JCI 103: 1527, 1999), we recently show that mitapivat, an oral PK activator, ameliorates anemia, reduces chronic hemolysis and improves RBC features in 4.2 mice (Matte A et al. EHA 2021).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...