Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
Community
1
PMCID
string
Sentences
string
ner
list
PMC11321678
Shown are representative images from at least three mice with similar results.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Shown", "are", "representative", "images", "from", "at", "least", "three", "mice...
PMC11266100
The lower electrotransfection efficiency when higher concentration of Mg ions is used can be explained by the increased activity of DNAse enzyme (Tullis and Price, 1974) or it can be hypothesized that Mg ions bind DNA to the cell surface with such strength that it cannot pass into the cell during EP (Haberl et al., 2010).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11680562
Fig. 7The drug release profile of six PXFCu anticancer gel formulation (a); The zero-order kinetics of PXFCu6 gel (b); The first order kinetic of PXFCu6 gel (c); korsmayar peppes kinetic model of PXFCu6 gel (d); Higuchi kinetic model of PXFCu6 gel (e); Hixcon crowell kinetic model of PXFCu6 gel (f) The drug release profile of six PXFCu anticancer gel formulation (a); The zero-order kinetics of PXFCu6 gel (b); The first order kinetic of PXFCu6 gel (c); korsmayar peppes kinetic model of PXFCu6 gel (d); Higuchi kinetic model of PXFCu6 gel (e); Hixcon crowell kinetic model of PXFCu6 gel (f) Several kinetic models were examined to clarify the release kinetics of PXFCu6, and the regression coefficient (R) was calculated to determine the most accurate fit (Fig. 7B–F).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
These data support that BMP regulation of hepcidin may be distinct from regulation by IL-6.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "data", "support", "that", "BMP", "regulation", "of...
PMC11772449
The results showed that overexpression of p38γ (D179A) significantly reduced the sensitivity of HCC to Sora compared with overexpression of p38γ (K56R), indicating that the effect of p38γ on the anti-HCC effect of Sora is dependent on its protein kinase activity.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612626
Multiple myeloma cells were then transfected with vectors that expressed FLAG-tagged forms of either β5/PSMB5 or β5i/PSMB8.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Multiple", "myeloma", "cells", "were", "then", ...
PMC11789597
As a result of CAV1 inhibition, MM cells are more sensitive to starvation, glutamine depletion, and glutamine transporter inhibition, and grow more slowly in vivo in a mouse model treated with bortezomib.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9910796
A, B) Double-labeling of pEP84R-Flag-expressing cells with rabbit anti-pEP84R (10-nm gold, green arrowheads) and mouse mAb anti-PDI (15 nm, black arrowheads) antibodies showing colocalization at ER (A, B), including the nuclear envelope, as well as Golgi (Go) membranes (B). (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11347429
y-axis: -log10 BH multiple testing adjusted p-values, x-axis: log2 fold change.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "y-axis", ":", "-log10", "BH", "multiple", "testing", "adjusted", ...
PMC11802855
Additionally, we merged modules with a distance of less than 0.25.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "we", "merged", "modules", "with", "a", "distance", "of", ...
PMC10631132
Osteoclasts differentiated from PBMC-derived iPSCs using the EB protocol showed clearly visible resorption pits on tiled full-well images acquired with a widefield microscope in phase-contrast mode A in comparison with undifferentiated negative controls (B).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9516447
Total protein from whole cell lysates were electrophoresed in 10% or 12% SDS-PAGE gels, transferred to Supported Nitrocellulose membrane (Bio-Rad Laboratories, Cat#1620097, Hercules, CA) and probed with the following antibodies.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11394730
A growing body of research indicates that the combination of medications shows better efficacy in treating cancer .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "growing", "body", "of", "research", "i...
PMC10723784
Note: *p < .05 and ***p < .001 compared to AREPE19, and p < .05, p < .001 compared to PNT2 cells. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Jaundice was common for pts across genotypes (M/M: 32.7%; M/NM: 44.4%; NM/NM: 25.0%).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Jaundic...
PMC11747467
Applying the luminal (including FOXA1 and GATA3) and basal (including CD44 and KRT5) markers, we observed the expression distribution of these genes in epithelial cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11459296
The remaining data are represented as the mean±SE of mean.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "remaining", "data", "are", "represented", "as", "the", "mean±SE", "of", "mean", "."...
PMC11659734
Preliminary results from a single experiment with 3D HepG2 spheroids showed a slight concentration‐related increase in micronucleus frequency both with BPE and BPP.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11291490
Moreover, the secretion levels of duIFNγ also could be enhanced post dusCD40L stimulation (Fig. 2a).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "the", "secretion", "l...
PMC11687167
The SLEDAI (an index of disease activity in SLE) and SLICC (a damage index) were positively associated with PCSK9 levels .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11588085
XIST expression analysis by RT-qPCR after KD of XIST and clonal selection in OVCAR3-KRAB and SKOV3-KRAB.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O" ], "tokens": [ "XIST", "expression", "analysis", "by", "RT...
PMC11562028
However, due to their structure and low water solubility, cell uptake of most of the natural medicines is low.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "d...
PMC9444294
Further information comes from techniques including RT-PCR (sometimes supported by Sanger sequencing) to identify the involved exons, or by hybrid capture or anchored multiplex sequencing strategies.27 Our lab has developed a NanoString assay designed to specifically identify and quantify the presence of multiple known possible fusion junctions in translocation-associated sarcomas within a single experimental setup.15 Compared to IHC tests, however, these molecular techniques require relatively expensive equipment, reagents, and trained personnel with sometimes lengthy turnaround.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11695546
The cells were put at 35°C for a further 24 h after the samples in levels from 1000 to 31.25 µg/mL was added after 24 h of attachment till merging.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11745355
Sci.
[ { "tags": [ "O", "O" ], "tokens": [ "Sci", "." ] } ]
PMC10530622
One alternative (candidate) gene is SLC26A6, expressed in intestinal and renal epithelia and coding for a bidirectional oxalate transporter.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "alter...
PMC11201245
The OC-FISH test was validated on 71 fixed primary cell cultures of ovarian cancer from 1999 to 2010 (Table 1).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "OC-FI...
PMC11638288
The function of NKp46 was initially described by the ability of NK cells injected into mice to produce monoclonal antibodies that block the lysis of NK-sensitive tumor cells .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11695623
And the diagnostic value of DCUN1D5 in lung adenocarcinoma was evaluated by drawing ROC curve.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "And", "the", "diagnostic", "value", "of", "DCUN1D5", "in", ...
PMC11551844
The spectra indicated a mixture of at least two compounds based on the intensities of peaks.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "spectra", "indicated", "a", "mixture", "of", ...
PMC6600253
The tumor-suppressive function of senescence provides an opportunity for the development of treatments that enhance senescence in clinical cancer therapy .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "tumor-suppressive", "...
PMC11755624
Its overexpression and stimulation with static (STAT3 inhibitor) reduced the expression of pro-inflammatory mediators , thus further supporting the importance of interplay between inflammatory responses and keratinocyte behavior.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
The prognosis in these groups was probably influenced by the predominantly elderly age of patients (over 60 years), and the aggressive course of the viral infection.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11806613
Quantification of protein expressions are shown on top.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Quantification", "of", "protein", "expressions", "are", "shown", "on", "top", "." ] } ]
PMC7570809
Hepatocellular carcinoma (HCC) is a primary malignancy of the liver that usually develops from a background of liver fibrosis and inflammation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hepatoc...
PMC9429973
Serum concentrations of 21 cytokines were assessed pre-tx and after 1 week of combination tx in a representative subset of 27 pts (n=9 per arm) by bead-based multiplex immunoassay (Eve Technologies, Calgary).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11354239
were all purchased from Sigma-Aldrich.
[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "were", "all", "purchased", "from", "Sigma-Aldrich", "." ] } ]
PMC9243326
A total of 13,214 sequences were annotated using the GO function classification library under the three broad categories: molecular function (17,422 unigenes), cellular component (48,494), and biological process (80,752). “
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11747467
This might be a consequence of its low expression of ERBB2.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "might", "be", "a", "consequence", "of", "its", "low", "expression", "of", ...
PMC6182045
When analyzed by RP-HPLC, both CHO and MGAT1 CHO purified preparations ran as a single peak, with the MGAT1 CHO derived protein preparation displaying a slightly more symmetrical peak and smaller trailing shoulder as compared to the CHO derived preparation (Figure 6B).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9351137
To answer this question, we used IFM to study the distribution of MRG15, Tip60, and YETI in S2 cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "To", ...
PMC11754094
Empirically, we and other groups observed that PEs are often accompanied by unwanted small indels.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Empirically", ",", "we", "and", "other", "groups", ...
PMC10024132
The population of γ9δ2 T cells is a battle-ready first line of defense that accounts for 1-5% of peripheral blood CD3 T cells in healthy adults .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
NPM1/ABL % values of contrived clinical samples in EDTA whole blood from the NPM1 Mutation Prototype Assay were consistent with those from two other comparator assays, RT-ddPCR, and Ipsogen NPM1 MutaQuant assay(Table 1).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11155445
In this section, the synthesis and structural aspects of such metal complexes are presented.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this", "section", ",", "the", "synthesis", "and", ...
PMC9429973
The nerve injury of BIPN mice was observed by measuring ethology, motor nerve conduction velocity, HE staining, electron microscope and ROS level.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973
Safety analyses were restricted up to and including Month 6.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Safety", "analyses", "were", "restricted", "up", "to", "and", "including", "Month", "6", "...
PMC10713411
Moreover, the energy, nucleotide, lipid and carbohydrate metabolisms were significantly activated in high-PRPCDGs-risk group.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "the", "energy", ",", "nucl...
PMC9681981
For all extracted RNAs, the A260/280 ratio was between 1.8 and 2.1.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "all", "extracted", "RNAs", ",", "the", "A260/280", "ratio", "w...
PMC11467964
Furthermore, ROC curve and K–M curve verified the excellent predictive ability of the BM‐related signature.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "ROC", "curve", "an...
PMC8750422
We further investigated whether suppression of GPR87 inhibited AKT-eNOS signaling.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "further", "investigated", "whether", "suppression", "of", "GPR87", "inhibited", "AKT-eNOS", ...
PMC9429973
A numerically greater proportion of pts who initiated RUX at ≤12 mo vs >12 mo achieved TSS50 at Wk 24 (56% vs 40%; P=0.0829; Table).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11682525
Additionally, transplantation of pre-conditioned cells contributes to the suppression of inflammatory factors and immune responses, fostering functional recovery ( 5 , 6 ).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10968586
Results on OLE-mediated effects on hepatoma cells are conflicting.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", "on", "OLE-mediated", "effects", "on", "hepatoma", "cells", "are", "conflicting", "." ] } ]
PMC9429973
L. Oosten, M. van Pel, B. van der Holt, E. Bach, M. Cross, H. Roelofs, P. Meij, B. Wieles, J. J. Zwaginga, A. Lankester, H. Veelken, U. Platzbecker, F. Sanchez-Guijo, M. Algeri, F. Locatelli, T. Devos, J. Cornelissen, D. Niederwieser, W. Fibbe Hematology; Nephrology, Leiden University Medical Center, Leiden; HOVON Data Center, Hematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands; Medical Clinic and Policlinic 1, Hematology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany; Clinical Pharmacy and Toxicology; Pediatrics, Leiden University Medical Center, Leiden, Netherlands; Hematology, IBSAL-Hospital Universitario de Salamanca, CIC and CIBERONC, University of Salamanca, Salamanca, Spain; Pediatric Hematology and Oncology, Cellular and Gene Therapy, Bambino Gesù Children’s Hospital, Sapienza, University of Rome, Rome, Italy; Hematology, University Hospitals Leuven and Department of Microbiology and Immunology, Laboratory of Molecular Immunology (Rega Institute), KU Leuven, Leuven, Belgium; Hematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands Background: Severe steroid-refractory acute graft-versus-host disease (SR-aGvHD) following allogeneic stem cell transplantation (HSCT) is associated with a high mortality rate.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11767725
The resultant production of IL-17 and IL-22 drives keratinocyte hyperproliferation and disrupts epidermal differentiation, creating conditions that favor dysbiosis .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "resultant", "producti...
PMC9545714
There was some overlap with the findings with 0.001% GTE, but also some differences.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "was", "some", "overlap", "with", "the", ...
PMC9065483
Cell lysates were collected 24 hpi and probed for phosphorylated EGFR, total EGFR, phosphorylated ERK1/2, total ERK1/2, and GAPDH by western blot.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9587298
In contrast, for flavonoids, a slight decrease was observed (Fig. 1a, chromatograms at 325 nm).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "contrast", ",", ...
PMC11535726
Kirschsteiniothelia usually exhibits both sexual and asexual morphs (Hawksworth 1985; Boonmee et al. 2012; Hyde et al. 2013; Sun et al. 2021; Xu et al. 2023).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6312945
The expression levels of miR-101 and miR-345 in BEL-7404 pSUPER.neo-miR-101 group and BEL-7404 pSUPER.neo-miR-345 group were significantly higher than those in BEL-7404 pSUPER.neo group (P<0.05).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O"...
PMC8524093
It can also enter and replicate in synovial and muscles fibroblasts, synovial macrophages, myoblasts, muscle satellite cells, chondrocytes, and osteoblast (Ozden et al., 2007; Hoarau et al., 2010; Chusri et al., 2011; Phuklia et al., 2013; Hussain et al., 2016; Lentscher et al., 2020; Pott et al., 2020).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5308810
All the experiments were performed in triplicate and the results were presented as means ± SD of three independent experiments (t-test, *p<0.05, **p<0.01, ***p<0.001).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10421378
The main impact and the significant novelty of the employed methodology lie in the prospect of facilitating the detection of dormant and injured bacterial cells as separate subpopulations.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
At an updated data cutoff performed in Sep 2020, 34.9% of pts in the Oral-AZA arm and 24.4% of pts in the PBO arm remained alive at ≥3 y from randomization.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Using qRT-PCR, we quantified DEK gene expression and the median expression was used as the cut-off point.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Using", "qRT-PCR", ",", "we", "quantif...
PMC10975211
The magainin II peptide demonstrated cytotoxic and antiproliferative effects against lung adenocarcinoma cells (A549) , bladder cancer cells (RT4, 647V, and 486P) , breast cancers cells (MDA-MB-231), and human mesothelioma (M14K) while showing no impact on normal human fibroblasts (3T3) .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O"...
PMC9429973
Survival curves were calculated with Kaplan-Meier method, and comparison of survival among the groups used log-rank test method.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Survival", "curves", "were", "cal...
PMC11723947
g Percentage of Tconv, defined as CD4CD45.1CD45.2H-2KThy1.1, in the spleen 21 days after engraftment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "g", "Percentage", "of", "Tconv", ",", "defined", ...
PMC10502403
An increased basal OCR/basal ECAR ratio was observed in NE1-pMHC-stimulated NE1-GMCs, which might reflect an inclination toward mitochondrial energy metabolism.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", "increased", ...
PMC11757230
To explore the mechanisms by which cADSCs influence canine LL cell proliferation, we investigated the apoptosis and cell cycle of LL cells co-cultured with or without cADSCs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Nonetheless, FLT3-ITD prognostic impact and allogeneic hematopoietic cell transplantation (alloHCT) indication in this setting might be redefined by the widespread use of FLT3 inhibitors.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9592219
Furthermore, we aimed to explore the mechanisms underlying the high expression of TOP2A and identify the possible targeted drugs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "we", ...
PMC11738017
A box plot of POU2AF1 transcript expression in samples with WT vs those with an SV from the CoMMpass data set. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "box", ...
PMC10380508
The next most common type is the KIRP subtype, which is characterized by papillary or tubular-papillary structures and accounts for 15–20% of RCCs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11802855
In the TT2 training set, we separately calculated the Median Absolute Deviation (MAD) for each gene.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "TT2", "training", ...
PMC3164356
The enriched GO cell compartment terms among the nonexpressed susceptibility genes shows that membrane proteins and DNA binding proteins are primarily not expressed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC11521786
Most of the agents evaluated in preclinical and clinical trials have been specific monoclonal antibodies (MAbs), with few examples of active immunotherapy directed against this receptor.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11779993
The dried S. plagiophyllum powder (1 kg) was macerated using 70% ethanol.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "dried", "S.", "plagiophyllum", "powder", "(", "1", ...
PMC9429973
Methods: The ongoing, prospective, open-label, 2-part, phase 1/2 BelaRd study (NCT04808037) aims to enroll 66 pts with TI NDMM from a Greek center.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
In human AML, we quantified SUCNR1 expression in peripheral blood mononuclear cells (PBMC) from AML patients versus healthy volunteers, and treated xenograft recipients of CD34+ AML cells with succinate or vehicle.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11599565
It is worth mentioning is that this analysis of the whole genome was performed after 72 h of cisplatin exposure.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "worth", "m...
PMC10955424
The gradient was started with 98 % A and increased to 30 % B in 4 min, then increased to 40 % B in 1 min and kept isocratic at 40 % B for another 3 min.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11721064
To analyze transcription factor (TF) activity, we employed the "SCENIC" algorithm (Aibar et al., 2017) (https://github.com/aertslab/SCENIC).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC8777939
A2780-ADR cells were seeded into six-well plates (2 × 10 cells/well) and were incubated overnight at 37 ℃ and 5% CO2.
[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "token...
PMC11025866
One mechanism identifies host genes that might have direct or downstream effects that cause EBV lytic genes to be expressed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "mechanism", "identifi...
PMC10873328
The mRNA expression level of TGFBI, AKAP12, GPC1 and TGM2 after transfected with HIF1a-plasmid. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mRNA", "expression", "level", "of", ...
PMC11568601
was used for color development.
[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "was", "used", "for", "color", "development", "." ] } ]
PMC11696576
The blue dashed lines are hydrogen bonds (distance between donor and acceptor 2.6–3.2 Å and donor-hydrogen-acceptor angle >135°) c The 2D interaction map of the compound after 200 ns representative MD simulation is shown.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
The treatment response and PFS of each patient were given in the swimmer plot (Figure 1).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "treatment", "response", "and", ...
PMC9473868
Cell viability was determined by an MTT (3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide) assay.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "viability", "was", "determined", "by", "an", "MTT", "(", "3-(...
PMC11224020
Together, these results show that coordinated upregulation of DC motility and CCR7 expression relies on nuclear accumulation of cPLA2, which requires an intact nuclear envelope, and point to DCs being equipped with an extremely accurate machinery to detect precise levels of cell shape changes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11745823
Recently, the implication of the RIT1 gene in tumours has gradually attracted attention, as the occurred mutations have been found to exhibit a close correlation with cancer occurrence and progression, such as lung adenocarcinoma , hepatocellular carcinoma , endometrial carcinoma and leukaemia , among others .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11515150
Schematic diagram of the two CD5 CAR lentiviral vectors (top panel) and expansion of T cells transduced with CD5 CARs in vitro for 13 days (bottom panel). (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8633974
Figure 3Lentiviral TatDE CRISPR Inactivates Latent HIV-1.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Figure", "3Lentiviral", "TatDE", "CRISPR", "Inactivates", "Latent", "HIV-1", "." ] } ]
PMC10523483
The levels of canonical histones H3 and H4, as well as another two somatic H1 variants H1.4 and H1.5, were not affected by H1.2 knockout (SI Appendix, Fig. S2 D and E).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11496728
Fig. 4Effect of Apaf1 knockout on CHO cell growth.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "Fig.", "4Effect", "of", "Apaf1", "knockout", "on", "CHO", "cell", "growth", "." ] } ]
PMC11291697
Moreover, knock-down of gtdc1 in zebrafish resulted in neurodevelopmental defects, including microcephalic head, as we observed in our proband.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", "...
PMC11155445
Dorairaj et al. synthesized metal complexes of acyl thiourea (62a–e) with [PdCl2(PPh3)2] in acetonitrile and DCM as a solvent in the presence of a few drops of triethyl amine (Fig. 12).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Targeting lactate metabolism could be a new approach to hamper MM survival and create a less suppressive immune environment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Targeting", "lactate", "metabolism", ...