Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
Community
1
PMCID
string
Sentences
string
ner
list
PMC11726848
We estimated the proliferative capacity of cell culture using the classical radiobiological method—clonogenic analysis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "estimated", "the", "proliferative", "capacity", ...
PMC4112127
Cholangiocarcinomas (CCs) are malignant tumors of cholangiocytes, the epithelial cells of the bile ducts.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cholangiocarcinomas", "(", "CCs", ")", "are", ...
PMC9429973
Ubiquitin E3 ligases target their substrates for ubiquitination, leading to proteasome-mediated degradation (Yang et al., 2010).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ubiquitin", "E3", "ligases",...
PMC11139449
The mean difference between the groups was estimated using the T-test or analysis of variance (one-way ANOVA or two-way ANOVA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mean"...
PMC11489175
The OTUs contain an OTU catalytic domain, an ubiquitin interaction domain (i.e., ubiquitin interacting motif), an ubiquitin associated domain, or Zinc finger domain 39.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11672881
Two dietary agents, curcumin (CU) and thymoquinone (TQ), have been widely studied for their anti-cancer properties in melanoma.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10547921
The highly toxic enediyne compounds are not suitable for direct use as anticancer agents, but the potency and mechanism of action of these antitumor antibiotics make them attractive ADC payloads.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5673955
Telomere length was measured triplicate in each sample.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Telomere", "length", "was", "measured", "triplicate", "in", "each", "sample", "." ] } ]
PMC8348645
RT-PCR: A semi-quantitative reverse transcriptase–polymerase chain reaction (RT-PCR) was carried out using the Techno Prime system to determine the levels of GAPDH, BCL II, and BAX gene mRNA expressions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10882807
Data, based on at least three independent experiments, are presented as the mean ± standard deviation (SD) and were analyzed by GraphPad Prism 7.0 (GraphPad Software, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8524093
Therefore, the use of NHP is an interesting choice regarding drug/vaccine development.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "the", "use", "of", "NHP", "is", "an", "interesting"...
PMC9325715
Cytotoxic effect of iron citrate and complex of Fe-bLTF in L929 and Caco-2 cells detected with the MTT reduction assay (values are expressed as a percentage of cell viability) and LDH release assay (values are expressed in mU/mL).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC10957991
n(CK5, ctrl) = 3; n(CK5, siRNA) = 3.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "n(CK5", ",", "ctrl", ")", "=", "3", ";", "n(CK5", ",", "siRNA",...
PMC10165258
At a later time point, the library of cisplatin or etoposide-containing droplets was introduced into the culture chip containing the EwS spheroids.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", ...
PMC11247842
Some chromosomes are overrepresented for these traits (BTA6, BTA12, BTA24, BTA25, BTA28), especially for CM , however, only a handful of QTL are consistently reported across studies.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4839679
97% of the differentially expressed genes (n = 2,393) underwent mild to moderate (0–2 log2 fold) levels of differential expression upon PBRM1 re-expression.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11757230
All animal experiments were approved by the Bioethics Committee of Nippon Veterinary and Life Science University (approval number 2021S-40; September 8, 2021 and 2024S-25; July 26, 2024).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11727062
Furthermore, Hua Chan Su, a herbal ingredient derived from the dried skin secretions of toads in the Bufonidae family, has demonstrated significant antitumor efficacy against malignant melanoma and the potential to reverse drug resistance in tumor cells. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11765678
A one-way analysis of variance (ANOVA) or Student’s t-test was used for statistical analysis using Graph Pad Prism (GraphPad Software, Inc, La Jolla, CA, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11521786
To determine if the effect of Mv-HER3-induced PAbs on these oncogenic receptors is traduced into an antitumor effect, we first evaluated their cytotoxic effect on several human tumor cell lines that express HER3, as well as HER1 and HER2 (including breast, prostate, and lung tumor cell lines).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10538569
This may block the conformational transition of Env at a pre-fusion intermediate step, and inhibit viral entry.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "may", "block", "the", "conform...
PMC10165258
However the Cascade Blue dye did not provide a consistent calibration range on 3 decades of concentrations.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", "the", "Cascade", "Blue", "dye", ...
PMC11577421
In the absence of BSA, the anisotropy was ∼0.05, consistent with previous findings.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "absence", "of", "BSA", ",", "the", "anis...
PMC9429973
Treatment with TAG demonstrated promising efficacy, with responses that enabled 5 of 8 pediatric pts, including 3 1L and 2 R/R, to be bridged to stem cell transplant.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9872547
These findings represented the positive regulatory effect of nano-curcumin on cancer cell apoptosis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "findings", "represented", "the", "positive", "regulatory", "effect", ...
PMC11612508
Plants and their components are extensively utilized in research to produce NPs due to their cost-effectiveness and eco-friendly nature.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Plants", "and", "their", "compone...
PMC9910796
Average coverage obtained for a covered base was 541x and the corresponding sequence analysis discarded the existence of any additional and non-desirable mutations in vEP84Ri genome.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11172027
NALM and NASeLM showed a reduction in cell growth and mitochondrial activity in both cell lines: While NALM and NASeLM showed almost identical measurements on Jurkat cells, NASeLM was much more effective on MTC-SK than the non-selenium-containing carrier, indicating that it has additional anti-chemoprotective effects.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellL...
PMC11759751
3Low-dose chidamide did not affect the proliferation, apoptosis and anti-tumor ability of prepared CD19 CAR T cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "3Low-dose", "chidamide", "did", "not", ...
PMC9429973
We also observed a distinct group of 9 cases aged 1-2 years, with recurrent STAG2-LMO2 rearrangements and a patient with inactivating STAG2 mutation and CELF1 enhancer hijacking by LMO2.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612794
Magnified view of the Mis12C-Head1 hydrophobic surface interacting with the binding region 2 of CENP-T. Left: The transparent surface model of Mis12C is overlaid on a cartoon model.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6222726
Its flowers are white and its fruits are up to 1.2 cm long with a black pit, almost completely covered by a yellow or orange pseudoaril.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11545737
GSDMD cleavage and palmitoylation are independent events and cleavage-deficient GSDMD was found still palmitoylated upon inflammasome activation and was still able to cause pyroptosis, even if less efficiently than palmitoylated GSDMD-N .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11496728
The use of CRISPR/Cas9 technology to accurately knock out certain key genes and to optimize culture processes can improve protein expression levels.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "use",...
PMC11541409
Addressing these factors is crucial to introducing CAR T therapy in GIST.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Addressing", "these", "factors", "is", "crucial", "to", "introducing", "CAR", "T...
PMC8540611
This insignificant effect is most likely caused by free nanoparticles detached from the complexes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "insignificant", "effect", "is", "most", "likely", "caused", ...
PMC9268620
However, in an event where apoptotic cells are not effectively removed by the phagocytic cells, apoptosis can progress into secondary necrosis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However...
PMC11772585
Increased expression of METTL1 is crucial in promoting cSCC growth both in vivo and in vitro, suggesting that targeting METTL1 could be a promising strategy for cSCC treatment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11697703
The observation of a common migration phenotype after Fezf2 or miR-193b-miR365 cluster overexpression in layer II-III neurons further supports our results revealing Fezf2 regulation of the miR-193b∼365 cluster, and is consistent with the interpretation that the migration defects previously observed after Fezf2 overexpression may be mediated by dysregulation of MAPK8 signal via abnormal upregulation of the miR-193b∼365.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10958426
DEGreg mainly locates in regions without CNVs and low CNV variation regions, and enriched in cytokine signaling genes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "DEGreg", "mainly", "locates", "in...
PMC11711127
Similarly, IFN regulatory factor 4 (IRF-4) expression, whilst essential for Th-2 generation, is expressed highly in Tregs with enhanced suppression of Th-2 cells (124), and there are similar reports of Treg expression of retinoic acid-related orphan receptor gamma t and STAT3 for Th-17 (125) and BCL-6 and T-follicular helper (126127) cell suppression.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5963610
Resistant 3LL-D122-tumor variants exhibit a quite diverse range of escape mechanisms .
[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Resistant", "3LL-D122-tumor", "variants", "exhibit", "a", "quite", "diverse", "range", ...
PMC11680391
From the perspective of the herd veterinarian, there is significant potential for more active engagement with communication strategies that have been empirically shown to be effective, such as motivational interviewing .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11777207
Twenty-four hours later, the mice were anesthetized and photoconverted through exposure to violet light for 1 min per shaved site using a 405-nm 100 mW/cm handheld laser pointer.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11297139
Top right: quantification of the volume of the extracted tumors.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Top", "right", ":", "quantification", "of", "the", "volume", "of", "the", "extracted"...
PMC11052306
According to literature reviews, the current treatments for cancers , and even those foreseen , do not display any information about the use of dendrimers in clinic.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11206502
Earlier studies have confirmed increased glucose and glutamine uptake, along with pyruvate and alanine production, in 5637 cell lines in vitro .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10547921
The platform enables antibody-mediated targeted delivery to achieve a high degree of tumor specificity, while using infrared light to activate the biophysical mechanism of the drug to accurately induce rapid death of cancer cells without harming the surrounding normal tissues.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11269933
However, the RMSD value of the Phos(S11)-PEP conformation remained lower than that of the WT-PEP conformation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "RMSD", "value", "of"...
PMC9960565
As also already observed by us in the monodentate dendrimers and by others , in the case of the bidentate metallodendrimers, although the amines groups from conjugated cisplatin could bond hydrogen from water increasing the hydrodynamic size, the interaction with phosphates ions also needs to be considered when analyzing the modest variations in the size of the metallodendrimers with increasing generations.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11429241
The A2780 cell line was cultured in 1640 medium (Gibco™, cat.
[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "A2780", "cell", "line", "was", "cultured", "in", ...
PMC11718809
The mammary gland is a unique organ in mammals, playing a crucial role in the reproductive process of mammals.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mammary", "gland", ...
PMC9429973
Unlimited number of lines of prior therapy are allowed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Unlimited", "number", "of", "lines", "of", "prior", "therapy", "are", "allowed", "." ] } ]
PMC11389534
UFL1 interacts with STING to prevent its ubiquitination and proteasomal degradation upon HSV‐1 infection.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "UFL1", "interacts", "with", "STING", "to", "prevent", "its", "ub...
PMC4395774
A control vector (PGK.GFP) which only expresses GFP and a second control expressing a mutant perforin with null function (PGK.PRFmut) were also generated.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10919056
Genes with statistical significance in the risk grouping (selected using the R package “Limma” with the criteria of p< 0.05, logFC = 1, and FDR< 1) were subjected to GO and KEGG enrichment analysis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7570809
The experiments were performed two times in duplicate.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "experiments", "were", "performed", "two", "times", "in", "duplicate", "." ] } ]
PMC11488203
A comparison of the more concentrated EV/exosome isolates also demonstrated an enhanced tetraspanin accumulation in the taxol EVs/exosomes and further enrichment of EV-markers in the SEC + UZ after removal of non-EV proteins (Fig. 3B, right panel).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10809689
Asterisks represent statistical significance (* p < 0.05, ** p < 0.001, and *** p < 0.0001) Cell proliferation rate changes in control, PMA, and PMA + Gal-9 groups for HL-60 and THP-1 cell lines.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11792766
In addition, NOAEC values of 0.15% and 0.2% v/v acetic acid were determined for Caco‐2 cell lines via MTT and NRU assays, respectively, as summarized in Table 2.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11763126
We synthesized biotin-labeled CBDP1 and Scr peptides and conducted biotin pull-down experiments to study the downstream targets of CBDP1 (Fig. 6A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", ...
PMC10165258
The mortality ratio is obtained by dividing this integral value by the theoretical integral PI value of a spheroid of identical area which would be 100% dead.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6450504
Rhodamine-labeled liposome penetration into the spheroids at different layers of depth.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Rhodamine-labeled", "liposome", "penetration", "into", "the", "spheroids", "at", "different", ...
PMC9388315
Finally, the relative genes expression was evaluated by 2 method.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Finally", ",", "the", "relative", "genes", "expression", "was", "evaluated", "by", "2...
PMC6742971
The studies involving human participants were reviewed and approved by Ethical Committee for Clinical Research of the Faculty of Medicine of the University of Lausanne.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973
Eligible patients had confirmed RBCD and COVID-19.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Eligible", "patients", "had", "confirmed", "RBCD", "and", "COVID-19", "." ] } ]
PMC11392912
Our results suggest that ‘Clo-miR-14,’ an exogenous miRNA present in Curcuma longa, absorbed through regular diet, has robust thermal stability at 100°C in humans.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11656657
For the in-silico study, the B4GALNT1 gene expression was evaluated as a prognostic tumor marker and as surrogate marker for GD2 expression level in patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973
Aims: Here, we aimed at identifying therapeutic targets on a patient individual level and in the surrounding of a living organism.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ...
PMC10578720
Data presented as the mean ± SD, n=3, *p<0.05, **p<0.01, ***p<0.001, ****p<0.001 (1-way ANOVA with Tukey post hoc test).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
The median age is 75 yrs (range, 47-90) with FL cohort 81 and R/R cohort 72.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "median", "...
PMC10847511
In addition, in the past decade, several high-throughput drug screening studies using these cell lines have been conducted by different groups, including the Genomics of Drug Sensitivity in Cancer (GDSC), the Cancer Therapeutic Response Portal (CTRP), and Profiling Relative Inhibition Simultaneously in Mixtures (PRISM), Genentech Cell Line Screening Initiative (gCSI), and others.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11787381
The purpose of this study was to verify these potentialities in rat hippocampal neuronal cultures damaged by Aβ-oligomers.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "purpose", "of", "this", "study"...
PMC10605143
We postulate that this inhibitor can be tested as an additional treatment for patients with TNBC.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "postulate", "that", "this", "inhibitor", "can", ...
PMC11787355
N(Tumor only)=4, N(Flu TCR-T cell)=8, and N(PTPRZ1 TCR-T cell)=7.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "N(Tumor", "only)=4", ",", "N(Flu", "TCR-T", "cell)=8", ",", "and", "N(PTPRZ1", "TCR-T...
PMC11711127
DCs bridge innate and adaptive responses through their ability to capture and present Ags to T cells, driving their differentiation for a tailored immune response.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11687167
IL-12 and T11TS immunotherapy can protect T cells from apoptosis and promote their survival through the PI3K/Akt pathway.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "IL-12", "and", "T11TS", "immunotherapy", ...
PMC11155445
complexes were found more effective in the reduction of nitrobenzene compared to Ru(ii) complexes of acyl thiourea which show less reduction activity.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "complex...
PMC11437637
As shown in Table 2, the numbers of total lymphocytes, CD3+, CD8+T, and NK cells were significantly lower (P < 0.001), and the numbers of CD19+B lymphocytes (P = 0.028), and the ratios of CD4+/CD8+ (P < 0.001) were greater in EC patients than in healthy individuals.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Results: Bendamustine was well tolerated, with grade 3-4 transfusion-dependent anemia in 56% (46/81) of patients, and 43% (35/81) grade 3-4.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11519077
In several IBD investigations, Caco-2 cells were employed as an advanced in vitro triple-culture model [13–15].
[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "several", "IBD", "...
PMC10253973
Drug combinations were found to demonstrate synergy of action, facilitate dose reduction and minimize drug resistance in clinical trials but also lead to adverse reactions .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11021472
However, MYB protein and transcript levels were not changed upon circZDHHC11 knockdown, neither did we observe consistent changes for the other network components: MYC and miR-150 (Supplemental Fig. 4B,C,D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10135767
Cells were seeded on the cell culture plate 1 d in advance and transfected with the plasmid at a cell confluence degree of 60–80% using the transfection reagent (Zeta-life, CA, USA) in accordance with the manufacturer’s guidelines.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11143482
Characterisation of the OS tumour bearing mouse model showed: (i) body weight increased gradually after 25 days in all groups but significantly decrease in mice inoculated with 3 × 10 of cancer cells compared to other two groups; (ii) food intakes have been shown to be significantly lower in mice injected with 3 × 10 cancer cells after 25 days of treatment; (iii) visible tumour was detected starting on Day 11 in mice inoculated with 3 × 10 cancer cells and slow growth detected in mice injected with 1 × 10 cancer cells as it appears to produce only small volume of tumour (iv) lung metastatic were observed in mice post 25 days of tumour cells inoculated with 3 × 10 cancer cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11266100
Right after electroporation, the cells were moved to a 48-well plate and kept on ice for 10 min.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Right", "after", "electroporation", ...
PMC11754432
To see whether reduced lipid peroxidation detected with ALOX15B silencing also correlates with reduced NRF2 activation, gene expression of NRF2 targets was analysed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11307990
1640 medium, phosphate-buffered saline (PBS), and fetal bovine serum (FBS) were purchased from Gibco BRL (Grand Island, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10507284
The R software (version 4.0.1) and GraphPad Prism (version 9.0.0) were applied for statistical analysis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "R", "software", "(", ...
PMC4485786
In vitro, growth arrest of A204 sarcoma cells induced by IFN-γ and TNF was accompanied by an immediate and highly significant increase (10-fold compared to untreated control) of cyclin dependent kinase inhibitor p21, which in skeletal muscle intrinsically withdraws the cells from cycling (Fig. 7A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11351758
Then, pore opening was triggered by the generation of mROS upon the photodecomposition of the indicator.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "pore", "opening", "was", "trig...
PMC11291697
Genes having a fold change absolute value of log2-Ratio ≥1 and a posterior probability ≥0.8 were considered as differentially expressed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Genes", "having", "a", ...
PMC11190538
The C-phycocyanin concentration was 19.25 %, C-phycocyanin purity ratio was found to be of reagent grade (0.15).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "C-phycocyanin", "conc...
PMC11055510
miR-135a-3p inhibitor up-regulated the protein level of ILRAP (Fig. 6G).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "miR-135a-3p", "inhibitor", "up-regulated", "the", "protein", "level", "of", ...
PMC9512971
The study was registered on ClinicalTrials.gov (NCT04657497) and the Japan Registry for Clinical Trials (jRCT2031200198).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "study", "was", "registered...
PMC11155445
The proton conductivity increased with the increase in humidity and temperature.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "proton", "conductivity", "increased", "with", "the", "increase", "in", "humidity", ...
PMC11733919
FT-IR spectra of STV functionalized MNP (MNP@STV). (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "FT-IR", "spectra", "of", "STV", "functionalized", "MNP", "(", "MNP@STV", ")", ".", "(" ...
PMC11599565
Tissue sections were incubated with conjugated secondary antibodies (Cell Signaling, Cambridge, UK) diluted in 2.5% goat serum in PBST for 120 min at room temperature according to the manufacturers’ recommendations.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11751675
These findings suggest that enantiomeric sesquiterpene lactones may have the potential to work synergistically with other antiviral agents in the treatment of HBV infection.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11720808
P < 0.01 compared with the 0 μM group.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", "<", "0.01", "compared", "with", "the", "0", "μM", "group", "." ] } ]