OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC11371747	CHO/C5 cells were genetically modified to be deficient in RFC activity, and do not express PCFT (Lasry et al., 2008).	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "token...
PMC6034753	Protein complexes were pulled out using (Figure 2C) rabbit anti-Meq and (Figure 2D) anti FLAG.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Protein", "complexes", "were", "p...
PMC8567602	Importantly, although reduced in abundance, CBAF is not absent from synovial sarcoma chromatin, where it includes the fusion and SMARCB1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Importa...
PMC11767725	For example, SCFAs, derived from probiotic fermentation, not only suppress pathogenic biofilm formation but also enhance keratinocyte differentiation and lipid metabolism.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11727145	30022; Vector Laboratories) to block non-specific binding.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "30022", ";", "Vector", "Laboratories", ")", "to", "block", "non-specific", "binding", "." ] } ]
PMC10522430	Employing the HeLa cell line as a research model, four groups were studied: KN (media and DMSO), K+ (doxorubicin 10 μg/mL), P1 (G. applanatum extract 200 μg/mL), and P2 (G. applanatum extract 400 μg/mL).	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Methods: Patients with active MM were treated with VRD, autologous stem cell transplantation and maintenance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Methods", ":", "Patients", "with", "active", ...
PMC11562028	The tumors of mice in the 5-FU group and the Re-CDs group were significantly inhibited at the beginning of the experiment (0–6 days).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10728200	H GIST-T1 and 882 cells were treated with IM (50 nM for T1 and 200 nM for 882) for 24 h with or without the overexpression of GPX4.	[ { "tags": [ "B-CellLine", "I-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", ...
PMC11012012	Pathological CLL B cells from patients with CLL showed significantly decreased expression of SLAMF1/CD150 in comparison with normal B cells from healthy control subjects or normal polyclonal B cells present in CLL patient samples .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11001582	n = 5 mice per genotype, one-way ANOVA, Bonferroni’s multiple comparison.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "n", "=", "5", "mice", "per", "genotype", ",", "one-way", "...
PMC11453018	Data are presented as mean expression levels.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "presented", "as", "mean", "expression", "levels", "." ] } ]
PMC11429241	However, PEGDA was preferable in the case of spheroidic scaffolds for the A2780 cell line.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "However", ",", "PEGDA", "was", "preferable", ...
PMC7090062	It is worth noting that inhibiting autophagy does not seem to work in all situations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "worth", "noting", "that", "inhibiting", "autoph...
PMC11781181	Therefore, we hypothesized that circulating exosomal miR-375-3p entered keratinocyte, promoting cellular oxidized PUFA and substantially downregulating both FSP1 and FTH1 expression, inducing the CoQ-dependent and ferritinophagy-mediated ferroptosis pathway in SJS/TEN (Fig. 8).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7709199	In the first instance, we expressed the glycosylation mutants in HEK293T and HEK293S MGAT1 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "B-CellLine", "B-CellLine", "O", "O" ], "tokens": [ "In", "the", "first", ...
PMC11755519	EVs are widely studied for their role in cancer development.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "EVs", "are", "widely", "studied", "for", "their", "role", "in", "cancer", "development", "...
PMC9509578	Liposomes can also be utilized as a co-delivery system to deliver a chemotherapeutic agent along with inhibitors to sensitize cancer cells to anticancer drugs .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11264242	FLAG ChIP-qPCR analysis of SS18-SSX2 occupancy at the FYN gene locus before and after FK228 treatment. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "FLAG", "ChIP-qPCR", "analysis", "of", "SS18-SSX2"...
PMC11694625	Firstly, the crystal structures of receptors, DNA (PDB ID: 2MG8), CDK1 (PDB ID:6GU7), CDK2 (PDB ID: 4BGH), CDK4 (2W9Z), CDK8 (5i5Z), were downloaded from Protein Data Bank (http://www.rcsb.org./pdb).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9250505	Six animals in each group.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Six", "animals", "in", "each", "group", "." ] } ]
PMC4443654	TAD boundaries were called using software provided by Dixon et al. with recommended parameters.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TAD", "boundaries", "were", "called", "using", "software", "provided",...
PMC11673902	Through a combination of optical stretching and microfluidics, i.e., the use of optical fibers to capture and stretch flowing cells, they measured the optical deformability of the mouse fibroblast cell line BALB/3T3 and its cancerous counterpart and human mammary epithelial cells and their cancerous counterparts and found that the optical deformability of highly metastatic breast cancer cells, MDA-MB-231, was significantly reduced by all-trans retinoic acid treatment, which was attributed to the fact that all-trans retinoic acid reduced the metastatic properties of this cell .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5261804	We hypothesized that cell lines with mutant PTEN would have increased dependence on PPIs in the PI3K-AKT pathway, while those with mutant APC would exhibit increased dependence on β-catenin (CTNNB1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10291556	For instance, administration of Pt(II) complex 1 revealed no antitumor activity in BD-IX rats with peritoneal carcinomatosis, while a potent anticancer effect on an oral cancer xenograft model on BALB/c nude mice was reported.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9918897	To maximize the quality and reliability of this published research, we used the ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973	Among patients with related donors, 11 were transplanted with a myeloablative regimen and 2 with a non-myeloablative regimen.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Among", "patients", "with", "rela...
PMC11627398	However, the impacts of cuproptosis-related genes in septic shock have not been clearly demonstrated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "impacts", "of", "cuproptosis-related", ...
PMC9635307	Therefore, overexpression of CEACAM1 may suppress BCR-mediated B cell activation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "overexpression", "of", "CEACAM1", "may", "suppress", "BCR-mediated", "B",...
PMC11794847	RNA sequencing illuminated a potential relationship between HVEM and GPT2, an enzyme tied to amino acid metabolism and cellular energetics.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RNA", "sequencing", ...
PMC9848491	The expression of 47 immune checkpoint genes was calculated and demonstrated using the packages “limma”, “Reshape2” and “ggPUbr”.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9220170	Similar results on increased expression of pro-apoptotic genes with reduced SELENOM activity were demonstrated in HT22 hippocampal cells and C8-D1A cerebellar cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "...
PMC11658074	Confidence intervals were determined at the 95% confidence level, and P < 0.05 was considered to indicate statistical significance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Confidence", "intervals...
PMC5673060	The top 10 most intense ions were fragmented using enhanced ion trap scans.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "top", "10", "most", "intense", "ions", "were", "fragmented", "...
PMC6450504	PEG can also activate the complement system and provoke serious side effects such as anaphylaxis (Mima et al., 2015; Yang & Lai, 2015).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11768927	Their findings demonstrated that both antiviral treatments significantly reduced VSV replication, thereby decreasing viral neurotoxicity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Their", "findings", "demonstrated", "that", "both", "a...
PMC11535726	Polymerase Chain Reaction (PCR) was employed for DNA template amplification, using the following primer pairs: ITS5/ITS4 for ITS, NS1/NS4 for SSU (White et al. 1990) and LR0R/LR5 for LSU (Vilgalys and Hester 1990; Cubeta et al. 1991).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10729469	p < 0.05, p < 0.01, p < 0.001, ***p < 0.0001 Adoptive transfer of TCRAβ-Tregs reduces reactive microglia in APP/PS1 mice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11190538	Small letters differ significantly (p ≤ 0.05) in treatments and capital letters between storage periods.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Small", "letters", "differ", "significantly", "("...
PMC9429973	Methods: Thirty-eight patients were recruited from the ALL‐BFM 2000/2009, CoALL97/03/09, and ALL‐REZ BFM 2002 trials or from Schneider Children’s Medical Center of Israel at time points of initial diagnosis, remission, and relapse.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11049294	Results: Flow cytometric detection of specific AGAL activity is feasible with fluorescently labelled Gb3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "Flow", "cytometric", "detection", "of", "sp...
PMC11473843	CompuSyn creates combination index (CI) values, where CI < 0.75 indicates synergism, CI = 0.75–1.25 additive effects, and CI > 1.25 antagonism.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10965680	The remaining SNPs were annotated with a reference goat assembly based on their positions using ANNOVAR v2016- 02–01 (Danecek et al., 2011).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC7039683	Reactions were stopped by adding PBS supplemented with 5% fetal bovine serum (Life technologies).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Reactions", "were", "stopped", "by", "adding", ...
PMC11478724	The US FDA approved its use as an infusion medicine on July 2, 2005.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "US", "FDA", "approved", "its", "use", "as", "a...
PMC2196094	946, and one base pair deleted at position 1024) (24).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "946", ",", "and", "one", "base", "pair", "deleted", "at", ...
PMC7369657	The expression of cleaved-caspase-3 in CQDs group was higher compared to the control group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "expression", "of", "cleaved-caspase-3", "in", "CQDs", "group", ...
PMC11354239	Moreover, it has been found that the production of IFN-γ by NK cells is increased by the stimulation of OX40 by agonistic monoclonal antibodies, but not by OX40L .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11653552	Consistent with these findings, miR-590-3p could be a good candidate for detection in liquid biopsy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consistent", "with", "these", "findings", ...
PMC11680391	We did not expect complete agreement, but a discrepancy of this magnitude was unexpected.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "did", "not", "expect", "complete", "agreement", ",", ...
PMC9847912	Plasmid pROD9 was provided by Michael Emerman.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Plasmid", "pROD9", "was", "provided", "by", "Michael", "Emerman", "." ] } ]
PMC11461874	See also Supplementary Fig. S1.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "See", "also", "Supplementary", "Fig.", "S1", "." ] } ]
PMC11680982	For 400 nM CDK4/6i + 100 nM ET: shNC vs. shHER2, P = 0.019.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "400", "nM", "CDK4/6i", "+", "100", "nM", ...
PMC11026382	All amplicons were individually quantified using with Quant-iT™ PicoGreen™ dsDNA Assay Kit (ThermoFisher Scientific) and mixed in equimolar ratio, with a final target amount greater than or equal to 2000 ng.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11082662	Furthermore, we constructed SMPDL3B low-expression cell lines using knockout assays based on these two cell lines (Figure 4B,4C; P<0.0001).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Further...
PMC8140214	Treated cells were incubated at 37ºC with 5% CO2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Treated", "cells", "were", "incubated", "at", "37ºC", "with", "5", "%", "CO2", "." ] ...
PMC11747467	In summary, luminal cells were more sensitive to RC48 than basal ones.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "summary", ",", "luminal", "cells", "were", "more", "sensitive", ...
PMC11001582	Brains and spinal cords were dissected and postfixed in 4% PFA at 4 °C for 2 h. After fixation, brains and spinal cords were washed with PBS, allowed to sink in 30% sucrose solution at 4 °C, then stored in 0.02% sodium azide at 4 °C until further processing.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11754291	The Alamar Blue assay showed that most blue light parameters did not significantly reduce cellular metabolic activity, except for the highest intensity (50 mW/cm, 50 J/cm), as well as the UVA condition (15 mW/cm, 20 J/cm).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11143482	In addition, mice also have a shorter life span than other animals .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "mice", "also", "have", "a", "shorter", "life",...
PMC11129910	The tissue samples were obtained through the SIU Cancer Institute Tumor Bank and Memorial Medical Center.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "tissue", "samples", "were", "obtained", "throug...
PMC11637820	The plate was incubated for a period of 10 min in the dark and the absorbance was measured at 540 nm using a multi-mode plate reader (Molecular Devices, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Summary/Conclusion: The triplet Bendamustine-Bortezomib-Dexamethasone has shown significant efficacy in a particularly severe setting of patients, relapsed and refractory to all available therapeutic resources, and, in particular cases, it could be considered as a bridge to a second autologous or allogenic SCT,also after failure of novel agents.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4443654	Given the correlations seen between Hi-C eigenvectors from different cell types (Figure 1) and the similar predictive power of cell-type-specific models (Figure 2A), one might assume that a similar combination of informative variables appears in each of the models.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11748335	DNA methylation is another extensively researched layer of epigenetic modification, where DNA methyltransferases add a methyl group to cytosine at CpG sites, forming 5-methylcytosine .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11803149	GSEA also revealed significant downregulation in hallmark gene sets of Myc targets in aged OT-I TCR-T cells compared to young cells ( Figure 5A ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11594074	Epigenetic processes are heritable and reversible and include a multitude of known processes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Epigenetic", "processes", "are", "heritable", "and", "reversible", "and", "...
PMC11301242	Blue circles indicate the predicted neo-loops induced by structural variations within the circular amplification regions. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Blue", "circles", "indicate", "the", "predicted", "neo...
PMC11045125	To evaluate variants, RNA-seq read files were processed through nf-core rnavar release 1.0.0 with STAR 2-7-10a and SnpEff 5.1d .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11783017	Indeed, some studies have suggested that abnormally high levels of MYC may promote resistance to immunotherapy, particularly by inhibiting the extrinsic immune response against tumor cells [, , ].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7823217	As a drug screening platform, bioprinting should be applicable to several cancer types including breast cancer, GBM, cervical cancer, lung cancer and ovarian cancer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8998437	In the type II BL cell lines in our study, we did not detect LMP2A or LMP2B transcripts (Figure 1D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC10578720	Data presented as the mean ± SD, n=6.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "presented", "as", "the", "mean", "±", "SD", ",", "n=6", "." ] } ]
PMC11638288	This suppression occurs because overexpression of miR-224 can protect prostate cancer cells from NK cell invasion by inhibiting the NCR1/NKp46 signaling pathway.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "supp...
PMC11612626	Compound A increased CTL-mediated cytotoxicity of tumor cells, which was measured by gating for CD138, annexin V, and PI cells at E:T 2:1 and 3:1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11718817	To define the role of macrophages as platform cells for integrating antigen-dependent motility signals, macrophages were polarized toward an M2 phenotype, and then treated with LPS and nigericin or not in order to activate the NLRP3 inflammasome.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10142392	Due to the difficulty of recrystallizing the short and grafted branches of PCL under administration conditions, the micelles prepared from these toothbrush-shaped copolymers exhibited a higher loading capacity for DOX than the micelles formed by the linear polymer PEG-b-PCL.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11380329	However, Lawler et al. observed no associations between serum vitamin D and ki67 marker expression in colorectal cancer patients, whereas an inverse association between vitamin D binding protein and tumor Ki67 explains the reduced mortality .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11413393	Source data are provided as a Source Data file.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Source", "data", "are", "provided", "as", "a", "Source", "Data", "file", "." ] } ]
PMC11576293	Collectively, the fulfillment of all or most of Lipinski’s parameters indicates the high probability of a compound in being a drug-candidate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Collect...
PMC11359735	Sporozoites, inoculated into the skin of the vertebrate host by an infected mosquito, are motile and must enter blood vessels to go to the liver where they enter hepatocytes and develop into the next life cycle stage (9).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10993311	BRCA1-A complex, a tumor suppressor, has been associated with ovarian (Alkailani et al., 2021) and breast (Bai et al., 2021) cancer in women, and adipocytes can alter the expression of this gene (Tianyi et al., 2018).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Future studies on the epidemiology, morbidity, mortality, and economic burden associated with NTDT are needed to understand the clinical and economic impact experienced by these patients and society.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10560648	In the present study, it was shown that C. Andromeda venom can reduce Bcl-2 gene expression and increase cell apoptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "pres...
PMC10669128	In the field of sarcoma research, non-murine models, such as genetically modified zebrafish, have also been developed, but they primarily concern rhabdomyosarcomas, Ewing’s sarcoma, malignant peripheral nerve sheath tumors, chordomas , and, to the best of our knowledge, only one liposarcoma case .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11754436	The tumor size were measured after different treatments. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "tumor", "size", "were", "measured", "after", "different", "treatments", ".", "(" ] } ]
PMC9429973	There was no significant difference in distribution of frequency alleles and GSTP1 A313G (χ2=0,89, p=0,34), GSTP1 C341T (χ2=0,11 R=0,74), MDR1 C1236T (χ2=0,01, p=0,93), MDR1 G2677T (χ2=0,37, p=0,54), MDR1 C3435T (χ2=0,01, р=0,97) genotypes between group of Hodgkin’s lymphoma patients with complete/partial remission and group with progressive/refractory or relapsed lymphoma.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11522251	The relative cell viability was determined using the MTT test.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "relative", "cell", "viability", "was", "determined", "using", "the", "MTT", "test", ...
PMC11676674	CHO-K1 cells were seeded at a density of 30,000/well in 6-well plates in a volume of 1.5 mL of medium and were incubated in a humidified atmosphere at 37 °C with 5% CO2 prior to the addition of the test samples.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11786156	Such signaling can also be generated from tumor stromal cells such as tumor-infiltrating lymphocytes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Such", "signaling", "can", "also", "be", "generated", "from", "t...
PMC11335267	Treatments took place 30 min before lights were off, and food intake was determined 3, 6 and 12 h later.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Treatments", ...
PMC8193046	Red mark: conserved part of the novel substructure. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Red", "mark", ":", "conserved", "part", "of", "the", "novel", "substructure", ".", "(" ...
PMC11394730	Many of these substances have anti-inflammatory, antioxidant, and anti-proliferative qualities, which in turn make them desirable candidates for cancer biology interventions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9398137	Several small-molecule MCL1 inhibitors are currently being evaluated in prospective clinical trials in patients with various cancers (28).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Several", "small-molecule", ...
PMC6461034	Activation loop analyses inherently suffer from a focus on a small protein segment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Activation", "loop", "analyses", "inherently", "suffer", "from", "a", "focu...
PMC11762280	E Flowchart of DSF treatment or vehicle treatment for acute UVB skin injury model in WT mice (48 h after 430 mJ/cm UVB irradiation).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11699178	The understanding of these molecular mechanisms provides important molecular targets for the development of ovarian cancer treatment strategies and may lead to more effective personalized therapies for patients, improving treatment outcomes and survival rates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	These findings further support the positive efficacy of PEG on hematologic parameters and provide evidence for the role of proximal complement inhibition on hematological and clinical improvements for patients with PNH.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2614416	The nano-HPLC is a Paradigm MS4B Multi-Dimensional HPLC equipped with a Michrom Paradigm AS1 refrigerated autosampler and XCalibur software plugin (Michrom BioResources, Auburn, CA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7602170	PDGFRA-mutated GIST patients usually benefit from imatinib or other TKIs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PDGFRA-mutated", "GIST", "patients", "usually", "benefit", "from", "imatinib", "or", "other", "T...

PMC11371747

CHO/C5 cells were genetically modified to be deficient in RFC activity, and do not express PCFT (Lasry et al., 2008).

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PMC6034753

Protein complexes were pulled out using (Figure 2C) rabbit anti-Meq and (Figure 2D) anti FLAG.

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PMC8567602

Importantly, although reduced in abundance, CBAF is not absent from synovial sarcoma chromatin, where it includes the fusion and SMARCB1.

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PMC11767725

For example, SCFAs, derived from probiotic fermentation, not only suppress pathogenic biofilm formation but also enhance keratinocyte differentiation and lipid metabolism.

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PMC11727145

30022; Vector Laboratories) to block non-specific binding.

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PMC10522430

Employing the HeLa cell line as a research model, four groups were studied: KN (media and DMSO), K+ (doxorubicin 10 μg/mL), P1 (G. applanatum extract 200 μg/mL), and P2 (G. applanatum extract 400 μg/mL).

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PMC9429973

Methods: Patients with active MM were treated with VRD, autologous stem cell transplantation and maintenance.

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PMC11562028

The tumors of mice in the 5-FU group and the Re-CDs group were significantly inhibited at the beginning of the experiment (0–6 days).

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PMC10728200

H GIST-T1 and 882 cells were treated with IM (50 nM for T1 and 200 nM for 882) for 24 h with or without the overexpression of GPX4.

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PMC11012012

Pathological CLL B cells from patients with CLL showed significantly decreased expression of SLAMF1/CD150 in comparison with normal B cells from healthy control subjects or normal polyclonal B cells present in CLL patient samples .

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PMC11001582

n = 5 mice per genotype, one-way ANOVA, Bonferroni’s multiple comparison.

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PMC11453018

Data are presented as mean expression levels.

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PMC11429241

However, PEGDA was preferable in the case of spheroidic scaffolds for the A2780 cell line.

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PMC7090062

It is worth noting that inhibiting autophagy does not seem to work in all situations.

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PMC11781181

Therefore, we hypothesized that circulating exosomal miR-375-3p entered keratinocyte, promoting cellular oxidized PUFA and substantially downregulating both FSP1 and FTH1 expression, inducing the CoQ-dependent and ferritinophagy-mediated ferroptosis pathway in SJS/TEN (Fig. 8).

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PMC7709199

In the first instance, we expressed the glycosylation mutants in HEK293T and HEK293S MGAT1 cells.

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PMC11755519

EVs are widely studied for their role in cancer development.

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PMC9509578

Liposomes can also be utilized as a co-delivery system to deliver a chemotherapeutic agent along with inhibitors to sensitize cancer cells to anticancer drugs .

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PMC11264242

FLAG ChIP-qPCR analysis of SS18-SSX2 occupancy at the FYN gene locus before and after FK228 treatment. (

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PMC11694625

Firstly, the crystal structures of receptors, DNA (PDB ID: 2MG8), CDK1 (PDB ID:6GU7), CDK2 (PDB ID: 4BGH), CDK4 (2W9Z), CDK8 (5i5Z), were downloaded from Protein Data Bank (http://www.rcsb.org./pdb).

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PMC9250505

Six animals in each group.

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Six", "animals", "in", "each", "group", "." ] } ]

PMC4443654

TAD boundaries were called using software provided by Dixon et al. with recommended parameters.

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PMC11673902

Through a combination of optical stretching and microfluidics, i.e., the use of optical fibers to capture and stretch flowing cells, they measured the optical deformability of the mouse fibroblast cell line BALB/3T3 and its cancerous counterpart and human mammary epithelial cells and their cancerous counterparts and found that the optical deformability of highly metastatic breast cancer cells, MDA-MB-231, was significantly reduced by all-trans retinoic acid treatment, which was attributed to the fact that all-trans retinoic acid reduced the metastatic properties of this cell .

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PMC5261804

We hypothesized that cell lines with mutant PTEN would have increased dependence on PPIs in the PI3K-AKT pathway, while those with mutant APC would exhibit increased dependence on β-catenin (CTNNB1).

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PMC10291556

For instance, administration of Pt(II) complex 1 revealed no antitumor activity in BD-IX rats with peritoneal carcinomatosis, while a potent anticancer effect on an oral cancer xenograft model on BALB/c nude mice was reported.

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PMC9918897

To maximize the quality and reliability of this published research, we used the ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) .

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PMC9429973

Among patients with related donors, 11 were transplanted with a myeloablative regimen and 2 with a non-myeloablative regimen.

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PMC11627398

However, the impacts of cuproptosis-related genes in septic shock have not been clearly demonstrated.

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PMC9635307

Therefore, overexpression of CEACAM1 may suppress BCR-mediated B cell activation.

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PMC11794847

RNA sequencing illuminated a potential relationship between HVEM and GPT2, an enzyme tied to amino acid metabolism and cellular energetics.

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PMC9848491

The expression of 47 immune checkpoint genes was calculated and demonstrated using the packages “limma”, “Reshape2” and “ggPUbr”.

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PMC9220170

Similar results on increased expression of pro-apoptotic genes with reduced SELENOM activity were demonstrated in HT22 hippocampal cells and C8-D1A cerebellar cells .

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PMC11658074

Confidence intervals were determined at the 95% confidence level, and P < 0.05 was considered to indicate statistical significance.

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PMC5673060

The top 10 most intense ions were fragmented using enhanced ion trap scans.

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PMC6450504

PEG can also activate the complement system and provoke serious side effects such as anaphylaxis (Mima et al., 2015; Yang & Lai, 2015).

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PMC11768927

Their findings demonstrated that both antiviral treatments significantly reduced VSV replication, thereby decreasing viral neurotoxicity.

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PMC11535726

Polymerase Chain Reaction (PCR) was employed for DNA template amplification, using the following primer pairs: ITS5/ITS4 for ITS, NS1/NS4 for SSU (White et al. 1990) and LR0R/LR5 for LSU (Vilgalys and Hester 1990; Cubeta et al. 1991).

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PMC10729469

p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 Adoptive transfer of TCRAβ-Tregs reduces reactive microglia in APP/PS1 mice.

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PMC11190538

Small letters differ significantly (p ≤ 0.05) in treatments and capital letters between storage periods.

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PMC9429973

Methods: Thirty-eight patients were recruited from the ALL‐BFM 2000/2009, CoALL97/03/09, and ALL‐REZ BFM 2002 trials or from Schneider Children’s Medical Center of Israel at time points of initial diagnosis, remission, and relapse.

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PMC11049294

Results: Flow cytometric detection of specific AGAL activity is feasible with fluorescently labelled Gb3.

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PMC11473843

CompuSyn creates combination index (CI) values, where CI < 0.75 indicates synergism, CI = 0.75–1.25 additive effects, and CI > 1.25 antagonism.

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PMC10965680

The remaining SNPs were annotated with a reference goat assembly based on their positions using ANNOVAR v2016- 02–01 (Danecek et al., 2011).

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PMC7039683

Reactions were stopped by adding PBS supplemented with 5% fetal bovine serum (Life technologies).

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PMC11478724

The US FDA approved its use as an infusion medicine on July 2, 2005.

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PMC2196094

946, and one base pair deleted at position 1024) (24).

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PMC7369657

The expression of cleaved-caspase-3 in CQDs group was higher compared to the control group.

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PMC11354239

Moreover, it has been found that the production of IFN-γ by NK cells is increased by the stimulation of OX40 by agonistic monoclonal antibodies, but not by OX40L .

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PMC11653552

Consistent with these findings, miR-590-3p could be a good candidate for detection in liquid biopsy.

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PMC11680391

We did not expect complete agreement, but a discrepancy of this magnitude was unexpected.

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PMC9847912

Plasmid pROD9 was provided by Michael Emerman.

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PMC11461874