Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
Community
1
PMCID
string
Sentences
string
ner
list
PMC11637276
While the individual siRNAs against the positive regulators gave consistent results, this was not the case for most of the negative regulators (on-target hits marked by a green star in Fig 1F).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11529598
Glioblastoma cell lines U251 and A172 were cultured with 10% fetal bovine serum containing DMEM (Dulbecco’s Modified Eagle Medium) at cell incubator set to 37℃ and 5% CO2.
[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11342785
These observations are intriguing, as the high concentrations and reduced-order of condensates could provide the multimerization, valency, and flexibility needed to bridge length-scales (18, 19, 20, 21, 22, 23).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11419566
According to existing research, PA extracted from P. cocos is an anticancer agent.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "According", "to", "existing", "research", ",", "PA", "extracted", ...
PMC11592008
Talabostat treatment: Cells were cultured with 3 or 30 μM talabostat (Cat# B3941; APExBIO Technology, Houston, TX, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11792090
Tumor volumes across different groups of mice. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tumor", "volumes", "across", "different", "groups", "of", "mice", ".", "(" ] } ]
PMC11783017
Assessment of cellular uptake behavior of Cis/Mn@Lipo-IL11 was conducted through flow cytometry and confocal laser scanning microscopy (CLSM).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Assessment", "of", "cellular...
PMC10748106
Among these, five iridoids are simple (non-glycosylated, including Genipin), and eight iridoids are glycosylated (including Geniposide).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Among",...
PMC8193046
Extension of positive pattern fingerprints: (A) dissection of C@PA-derived basic scaffolds into smaller heteroaromatic units (‘Scaffold Fragmentation’); (B) deduction of non-aromatic heterocycles from C@PA-derived clear positive and secondary positive hits (‘Heterocyclic Substructure Hopping’); and (C) deduction of heteroaromatic five-membered rings from C@PA-derived secondary positive heteroaromatic substructures (‘Heteroaromatic Substructure Hopping’).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Methods: In total, 724 primary EMD patients were diagnosed in the Czech Republic between 2004 and 2021 by using modern imaging methods.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11653533
Moreover, various crude extracts of F. sycomorus fruits have shown antimicrobial activity against four Gram-positive and Gram-negative bacterial strains, namely E.coli, Proteus spp, S. aureus, and Haemophilus influenza, in which 2 μg/ml butanol extract showed 8 ± 0.355, 12 ± 0.15, 10 ± 0.55 and 15 ± 0.14 nm zone of inhibition against those statins.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11298021
The fact that more than half of miRNA genes are located in "fragile sites" or genomic regions associated with cancer, indicates their profound stimulatory and inhibitory effects on tumors.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10808409
After 6 h, 100.00 ± 0.25% and 90.72 ± 1.07% of FA was released from the optimized mixed micelles (O1) and the TPGS mixed micelles (O2) respectively, whereas only 38.30 ± 0.78% was released from the standard.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11545868
Köksal Karayildirim, Ç., et al., suggested that prunetin induced apoptosis via caspase3 and TNF-α in bladder cancer RT-4 cells at 21.11 and 42.22 μg/mL .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", ...
PMC9031474
Because of the basic reaction conditions, 73 is formed as a C9 epimer.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Because", "of", "the", "basic", "reaction", "conditions", ",", "...
PMC7553912
Direct effects of OSM on gene expressions in the RTECs and renal fibroblasts.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Direct", "effects", "of", "OSM", "on", "gene", "expressions", "in", "...
PMC9960565
The CACO-2 cells proved to be mostly resistant to most of the compounds tested, including cisplatin.
[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "CACO-2", "cells", "proved", "to",...
PMC11756937
Indeed, it has been shown that these two non-integrating methods have a significantly lower number of copy number variants (CNVs), single nucleotide polymorphisms (SNPs) and chromosomal mosaicism relative to the lentiviral integrating method .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11755519
Furthermore, exosomes secreted by T24 and J82 cells also significantly promoted the migratory, invasive, and clonogenicity abilities of TSGH-8301 cells.
[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], ...
PMC9429973
Two patients relapsed.
[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "Two", "patients", "relapsed", "." ] } ]
PMC6889484
Although all three patient isolates replicated in the parental CEM cells with kinetics similar to that of the NL4-3 virus, with p24 CA levels peaking around day 7 (PtB-2) or days 9–11 (PtB-1 and PtB-3), no viral replication was detected in CEM/D128K cells for 42 days (Figure 3F).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11344246
Indirect proteins are those without evidence of genomic alteration in the MOC cohort.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Indirect", "proteins", "are", "those", "without", "evidence", "of", "genomi...
PMC8414691
Therefore, we wanted to evaluate the midbody association of SRCAP using both IFM and WB on isolated midbodies (see the “Methods” section).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10994876
Error bars represent the standard deviation (S.D) Our interest was to investigate whether YAP5SA-transfected cells in stable EPO-CHO-K1 populations could impact the production of global and specific proteins, particularly EPO, compared to the control population.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11629143
96‐well plates coated with Protein A were washed (PBS, 0.05% Tween20).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "96‐well", "plates", "coated", "with", "Protein", "A", "were...
PMC11549062
Statistical analysis was then performed based on the magnitude of the ratio.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "analysis", "was", "then", "performed", "based", "on", "the", "mag...
PMC7433824
Therefore, hormone‐sensitizing agents can be developed to enhance the antineoplastic of P4 even further.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "hormone‐sensitizing", "agents", "can", "be", ...
PMC2614416
The pellet was dispersed by adding 25 μL of MilliQ water and centrifuging for 10 minutes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "pellet", "was", "dispersed", "by", "adding", ...
PMC11761919
Group 1 tubes contained microcapsules (0.1 g) with PINs-internalized recombinant E. faecalis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Group", "1", "tubes", "contained", "microcapsules", "(", "0.1", ...
PMC11634794
Therefore, it becomes imperative and indispensable to identify reliable biomarkers while exploring potential molecular mechanisms for early diagnosis and precision treatment of RCC.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11244823
Indeed, the results showed that both gD1- and tag-sequences were present in the fusion proteins (S2 Fig).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Indeed", ",", "the", "...
PMC9429973
2.
[ { "tags": [ "O", "O" ], "tokens": [ "2", "." ] } ]
PMC11770130
After OCT-embedding, tissue sections in 10-μm thickness were first fixed in 4% (w/v) paraformaldehyde (Sigma) for 5 min, and washed twice with diethyl pyrocarbonate (DEPC)-treated PBS, followed by dehydration in an ethanol series.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11731614
Indeed, EVs hold great promise as novel disease biomarkers, therapeutic agents, and drug delivery systems.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Indeed", ",", "EVs", "hold", "great", ...
PMC8073654
In addition, our research group has screened the P-glycoprotein (P-gp) inhibitory activities of four solvent fractions (hexanes, chloroform, n-butanol, and aqueous) of Indonesian medicinal plants in P-gp overexpressing multidrug resistance (MDR) cancer cell lines (MES-SA/DX5, uterine; MCF-7/ADR, breast) .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9927933
On the other hand, DEPTOR could also activate AKT by relieving the feedback inhibition from mTORC1 to phosphoinositide 3-kinase (PI3K) signaling (23, 34, 35), or stabilize human epidermal growth factor receptor 2 (HER2) by abrogating β-TrCP–mediated degradation (36), or activate the TGF-β1/Smad3/Smad4/Snail pathway via mTOR inhibition (37).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11521786
3LL-R3 cells treated with anti-mErbB3 PAbs induced a reduction in cell viability compared to the preimmune sera control (4.98% ± 1.08% vs. 104.7% ± 8.79%, p < 0.0001).
[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
There were 6 patients (25%) with ISS I disease, 10 (41.7%) with ISS II disease, and 8 (33.3%) with ISS III disease.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8358006
g Gene ontology and pathway enrichment significance (−log10 (P value) values) are correlated for GO terms shared between 1172 GSDs marked genes and 388 GSDs targeted genes. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
C. Pontikoglou, A. Matheakakis, E. Stavroulaki, T. Chatzilygeroudi, A. Kourakli, A. Symeonidis, M. Dimou, P. Panayiotidis, G. Drakos, A. Koudouna, A. Galanopoulos, V. Kaliafentaki, P. Kanellou, D. Liapi, G. Tsirakis, A. Kolovou, E. Gavriilaki, A. Syrigou, I. Sakellari, S. Chatzileontiadou, M. Papaioannou, M. Bobola, P. Diamantopoulos, M. Mantzourani, N.-A. Viniou, M. Dellatola, A. Souravla, M. Pagoni, A. Megalakaki, I. Christodoulou, E. Vlachaki, S. Giannouli, V. Gkalea, C. Matsouka, I. Kotsianidis, G. Vassilopoulos, M. Protopappa, E. Hatzimichael, P. Zikos, G. N. Chalkiadakis, H. A. Papadaki Department of Hematology, University of Crete School of Medicine, Heraklion, Greece; Department of Hematology, Venizeleio-Pananeio General Hospital, Heraklion, Crete; Hematology Division, Department of Internal Medicine, University of Patras Medical School, Patras; First Propedeutic Department of Internal Medicine, National and Kapodistrian University; Clinical Hematology, G.Gennimatas District General Hospital, Athens; Department of Hematology, General Hospital “St. George”, Chania; Hematology Department-BMT Unit, George Papanicolaou Hospital; First Internal Medicine Department, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki; Department of Hematology-Blood donation, Pamakaristos General Hospital; First Department of Internal Medicine, Laikon General Hospital; Hematology and Lymphoma, Bone Marrow Transplant Unit, Evangelismos Hospital, Athens; Department of Hematology, Metaxa Anticancer Hospital, Piraeus; Second Department of Internal Medicine, Aristotle University of Thessaloniki Hippokration General Hospital, Thessaloniki; Second Department of Internal Medicine, National and Kapodistrian University; Hematology Departement, Alexandra General Hospital, Athens; Department of Hematology, Democritus University of Thrace, University Hospital, Alexandroupoli; Department of Hematology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa; Department of Hematology, General Hospital of Serres, Serres; Department of Hematology, University of Ioannina, Ioannina; Department of Hematology, General Hospital of Patras “St.Andrew”, Patras; Information Systems Unit Center of Information and Communication Technologies, University of Crete, Heraklion, Crete, Greece Background: ITP incidence is known to increase in adults aged >60 years and even more in men aged >75 years (Moulis G et al., Blood 2014; 124(22):3308).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11047729
This form circulates in the blood and when delivered to the kidney, the cytochrome P450 27B1 (CYP27B1) transforms it to calcitriol (1,25-hydroxyvitamin D) .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Median PFS and OS were not reached.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Median", "PFS", "and", "OS", "were", "not", "reached", "." ] } ]
PMC11803918
Typically, PDT can promote the release of damage-associated molecular patterns (DAMPs) from tumor cells, which may further promote the maturation of antigen-presenting cells (APCs) to present tumor antigens and activate the antitumor T-cell response.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8382973
After 14 days of continuous rectal and vaginal administration of the 2P23 gel, no 2P23 gel-related changes in physical signs or body weight were observed in rabbits.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10729469
18,783, Stemcell Technologies, Vancouver, CA), per the manufacturer’s instructions, and CD4+ T cells were enriched from splenic single cell suspension by negative selection using the EasySep™ mouse CD4+ T cell isolation cocktail.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10123657
Our experimental approach is simple but highly dependent on the absence of contaminant OP9 stromal cells detached from the spheroids in the preparation of co-cultured CCRF-CEM cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLin...
PMC11661040
Fig. 7CGREF1 knockdown inhibited the proliferation ability of osteosarcoma cells in vivo. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "7CGREF1", "knockdown", "inhibited", "the", "proliferation", "ability", ...
PMC9429973
There has been a significant increase in the percentage of single unit transfusions from 14% in 2014 to 65% in 2021; the trendline has a gradient of +7% / year (p=0.0009).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
E. Meseguer Martinez, J. Marco Buades, A. García Feria, P. Ribas García, M. J. Fernandez Llavador, A. López Gabaldon, S. Broseta Tormos, E. Francés Aracil, O. Cortés Ortega, E. Donato Martínez, M. Fernandez Zarzoso, M. Panero Ruiz, M. J. Cejalvo Andújar, A. Tolosa Muñoz, M. L. Juan Marco, D. Ivars Santacreu, E. Gómez Beltrán, M. J. Sayas Lloris Hematología y Hemoterapia, Hospital Universitario Doctor Peset, Valencia, Spain Background: The introduction of immunotherapies such as daratumumab, a CD38 monoclonal antibody has improved survival in multiple myeloma (MM), however a few considerations on minimal residual disease (MRD) assessment by flow cytometry have been raised and deserve our attention.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11359735
Nevertheless, we present them here for consideration.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Nevertheless", ",", "we", "present", "them", "here", "for", "consideration", "." ] } ]
PMC9424261
Data were analyzed using Student’s t test and expressed as mean ± SD. ***
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "were", "analyzed", "using", "Student", ...
PMC9780037
The conjunction of highly selective cyt c purification with better preservation at room temperature has the potential of extending usability of cyt c therapeutic delivery systems in settings with limited refrigeration.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11574029
Subsequently, a subcutaneous xenograft model was established in BALB/c-nude mice, and the results showed that knockdown of NOTCH3 significantly reduced tumor volume and weight, indicating a crucial role of NOTCH3 in tumor growth (Fig. 2F–K).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10988555
Figure 1 depicts the general behavior for this set of complexes, showing the electronic spectra of [CoCp(PPh3)(bipy)][(CF3SO3)2] (1), its precursor complex, and the free ligand.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9444294
The relative amount of chromatin for target gene loci was normalized to AM NC.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "relative", "amount", "of", "chromatin", "for", "target", ...
PMC11656380
A membrane-proximal RAM (RBP-jκ associated molecule) domain in NICD plays a critical role in facilitating the interaction between NOTCH and CSL.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", ...
PMC11474209
These cutting-edge biosensors will change things up for detecting and preventing dangerous algal blooms.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "cutting-edge", "biosensors", "will", "change", "things", "up"...
PMC11349530
The recent phase I study of tinengotinib, a multiple kinase inhibitor, as a single agent in patients with advanced solid tumors showed that tinengotinib was well tolerated and indicated potential clinical benefit in FGFR inhibitor-refractory cholangiocarcinoma, HER2-negative breast cancer (including triple-negative breast cancer), and castration-resistant prostate cancer.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11552389
For time-lapse monitoring, melanoma cells were imaged every 1 hour using a zenCELL Owl incubator microscope (innoME GmbH, supplied by LabLogic UK) for 96 hours.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9119314
Interestingly, 2 and 4–6 were not toxic to mice at doses of up to 100 mg/kg/dose.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interestingly", ",", "2", "and", "4–6", "we...
PMC8193046
This discovery ultimately showed that the 8 clear positive hits as derived from C@PA may indeed be supported by secondary positive hits, revealing the high potential of substructure extension in C@PA.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11750712
While an absence of circulating CAR T cells was observed, CAR T cells were readily detected in lymph node biopsy samples from sites of original disease suggesting homing to tumor sites.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11699178
Information on the antibodies used for Western Blot is provided in Table S2.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Information", "on", "the", "antibodies", "used", "for", "Western", "Blot", ...
PMC11271800
Therefore, it is important to explore more reliable markers of ICIs, in the hope that they can be used in combination with TKIs in sensitive patients to realize a new era of precision immunotherapy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11762280
ns not significant.
[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "ns", "not", "significant", "." ] } ]
PMC11657744
Additionally, we confirmed that CEP89 regulates AurA in Cep89 MEFs (Supplementary Fig. 5A–D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "we", "confirmed", ...
PMC11462673
To sum up, our research establishes the pivotal fuction of LDB1 in the tumorigenesis and progression of T-ALL cell lines.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "sum", "up",...
PMC9429973
Arm 1: pelabresib as monotherapy in RUX-intolerant, ineligible or refractory MF pts; Arm 2: pelabresib in combination with RUX as an ‘add-on’ in MF pts with suboptimal response to RUX; Arm 3: pelabresib combination therapy with RUX in JAKi-naïve MF pts.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11767582
NMR spectra match with previously published .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "NMR", "spectra", "match", "with", "previously", "published", "." ] } ]
PMC11286266
CRT depletion exposed a negative feedback loop implicating ATF6α in repressing IRE1 activity basally and overexpression of CRT reversed this repression.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CRT", "depletion", ...
PMC11787355
Hence, we characterized engrafted T cells by flow cytometry.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hence", ",", "we", "characterized", "engrafted", "T", "cells", "by", "flow", "cytometry", ...
PMC9611901
Future research regarding toxic aspects of vegetable tanning should focus on detailed phytochemical characterisation, explaining of interactions between the components included in the vegetable tanning procedures and determination of the concentration ranges in which their possible harmful effects would be minimised, while maintaining efficiency in leather processing.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11718109
The larger-sized VMAT2-positive vesicles in fibroblasts were strikingly reminiscent of those large vesicles (including DCVs) in DA neurons, which we further confirmed to be VMAT2-positive by CLEM.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11411131
The structure of Sec is similar to that of cysteine, with the sulfur in the thiol (R-SH) group substituted by selenium (R-SeH).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10944868
Protofilaments laterally associate to form the pseudo-helical structure of microtubules, with most having 13 protofilaments, though variations exist across species (Chaaban et al., 2017).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11707577
Images of the bio‐conjugated targeting agents’ penetration into A431 spheroids were acquired every 45 min with NIKON A1R confocal microscope.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Images", "of",...
PMC11055443
The immunophenotyping assay showed that AD-MSCs were negative for CD45 cell surface marker (0.05 %), but CD105, CD90, CD73, and Sca-1 surface markers were expressed at the mean percent of 76, 52, 61, and 74%, respectively (Fig. 2D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11792888
Finally, 150 µL DMSO was added to each well to dissolve the formazan crystals and the absorbance was detected at 560 nm.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Finally...
PMC11640247
Luciferase activity was measured using the dual-luciferase reporter assay system (Promega).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Luciferase", "activity", "was", "measured", "using", "the", "dual-luciferase", ...
PMC11756514
no L10119, Invitrogen) for 30 min, washed, and incubated for 30 min at 37°C with the FITC-labelled bacteria at bacteria to cell ratios ranging from 1 to 9.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3730428
We have previously shown that SAHA is unable to downregulate exogenous FLIP expression in either of these two cell line models.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "have", "pre...
PMC11551844
The injection room temperature was set to 60 °C and the injection volume was 1 μL. The setting for the oven is as follows: 60 °C (1.0 min), 120 °C (30°C min) for 3 minutes, 300 °C (15°C min) for 23 minutes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11655536
Cells were treated with HA at indicated concentration for 48 h. G The IC50 of HA on cell viability in RPMI-8226, U266, MM.1S and ARH-77 cell lines.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine"...
PMC10565698
and qRT-PCR.
[ { "tags": [ "O", "O", "O" ], "tokens": [ "and", "qRT-PCR", "." ] } ]
PMC11180402
The SOX2 overexpression construct pSin-EF2-SOX2 and the Myc-DNMT3b overexpression construct were purchased from Addgene (Cambridge, MA, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "SOX2", "ov...
PMC9429973
ED mainly due to severe bleeding, is a major obstacle in the management of APL.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ED", "mainly", "due", "to", "severe", "bleeding", ...
PMC11527437
Oncogenic viruses and driver mutations fulfill these criteria.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Oncogenic", "viruses", "and", "driver", "mutations", "fulfill", "these", "criteria", "." ] } ]
PMC9848491
We established a signature composed of eight ER stress-related lncRNAs (MIR34AHG, AC073842.2, PINK1AS, AC024909.2, MIR31HG, AC007422.2, AC061992.1, AC003102.1).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11320084
EMT can occur in various tissue types and developmental stages.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "EMT", "can", "occur", "in", "various", "tissue", "types", "and", "developmental", "stages", ...
PMC11650848
Additional isoforms have been identified for the human ZFP57 that are longer than the canonical form and start approximately 3 kilobases (kb) upstream from the transcription start site (TSS) of the original transcript.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9454178
The blots were then washed 3 times for 10 min with TBST (TBS with 0.1% Tween 20) and incubated with HRP-conjugated goat anti-rabbit or mouse IgG secondary antibodies (1:5000) for 1 h at room temperature.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10551595
Plate wells were coated with CCRF‐CEM and multidrug‐resistant RCCRF‐CEM cells, separately.
[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "Plate", "wells", "were", "coated", "with", "CCRF‐CEM", "and", "multi...
PMC10900886
We first inoculated Epstein–Barr virus-transformed B-lymphoblastoid cell line (BLCL) with EV-D68 strains from subclades A, B2, and A2.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC2777936
Graphs depict a representative experiment performed in triplicate.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Graphs", "depict", "a", "representative", "experiment", "performed", "in", "triplicate", "." ] } ]
PMC9429973
There is limited data about replacement therapy which is usually only required before surgical procedures or traumatic hemorrhages.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "is", "limited", "data", "abou...
PMC11656048
Molecular docking was performed by AutoDock software, and the molecular docking data were visualized using Discovery Studio2019.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Molecular", "docking", "was", "performed", ...
PMC11637284
This excludes that the interaction between TAC60 and p166 is due to ionic bonds.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "excludes", "that", "the", "interaction", "between", "TAC60", ...
PMC10093184
Consisting of slowly growing cells, these spheroids were smaller (approx.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consisting", "of", "slowly", "growing", "cells", ",", "these", "spheroids", "wer...
PMC11344246
Somatic point mutations from a cohort of MOC patients with a predicted deleterious consequence were extracted from Cheasley et al. (20) and mapped to the nodes of the differential network.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11641532
All plots were generated using “ggplot2” (v3.3.6) .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "plots", "were", "generated", "using", "“", "ggplot2", "”", "(", "v3.3.6", ...