OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC9424261	We found that after knocking out HERPUD1, the ubiquitination of GSS was reduced compared with the control group (Fig. 5B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", ...
PMC7504302	Besides, this model can help to explore novel molecular cues associated with MPM development and eventually enable the design of improved therapeutic strategies .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11422497	P < 0.05, **P < 0.01.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", "<", "0.05", ",", "", "", "P", "<", "0.01", "." ] } ]
PMC11461874	Statistical significance was determined for treatment, time and interaction by two-way ANOVA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "significance", "was", "determined", "for", "treatment", ",", ...
PMC11577421	Additionally, the interactions were characterized using MST with a Monolith NT.115 instrument (Nanotemper Technologies, Germany).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "the", "inter...
PMC11659734	Precipitation limited the range of BPP concentrations selected for the analysis of micronuclei.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Precipitation", "limited", "the", "range", "of", "BPP", "concentrations", "...
PMC11641630	The authors demonstrated that the fibronectin attachment protein (FAP) of the M. bovis BCG TICE strain binds to fibronectin or integrin α5β1 receptors on the surface of bladder tumor cells , interfering with cell migration.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11599565	Importantly, NCCs represent a unique, multipotent cell type in vertebrates which give rise to neuronal-related cell types including peripheral, enteric neurons and glial cells as well as craniofacial cartilage and bone cells, smooth muscle cells, melanocytes and, importantly, the mesenchyme.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8839885	2-methoxyestradiol (2ME2) is a natural metabolite of the endogenous estrogen hormone 17β-estradiol that is devoid of estrogenic activity .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "2-methoxyestradiol", "(", "2...
PMC9429973	In PBMCs incubated with Brusatol an increase of neoplastic B cells in apoptosis about 68% was observed (Brusatol: 91,9% ± 7,1%; Control: 23,7% ± 4,3%), and of 34% in cells incubated with ML385 (ML385: 57,9% ± 10,2%; Control: 23,7% ± 4,3%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6835428	PLL was used in place of the more commonly used PEI to minimize the known toxicity associated with PEI.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PLL", "was", "used", "in", ...
PMC3122064	Antibodies used are listed in Supplementary Methods.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Antibodies", "used", "are", "listed", "in", "Supplementary", "Methods", "." ] } ]
PMC9739791	The controllable activation was achieved by introducing a coumarin moiety into the oxaliplatin axial position (Figure 9).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "controllable", "activation", ...
PMC11787651	SWATH DIA scheme and LC gradients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SWATH", "DIA", "scheme", "and", "LC", "gradients", "." ] } ]
PMC9429973	Median guadecitabine exposure was 4 cycles and 3 cycles for TC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Median", "guadecitabine", "exposure", "was", "4", "cycles", "and", "3", "cycles", "fo...
PMC11047729	Moreover, it can be used as a drug carrier .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "it", "can", "be", "used", "as", "a", "drug", "carrier", "." ] } ]
PMC9429973	Summary/Conclusion: Optical Genome Mapping suggest to be very promising diagnostic tool that can complete the study of patients with myelofibrosis, especially in those with non-assessable karyotype.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11092382	Han et al. used a mouse model of LPS-induced ALI and reported that sophocarpine treatment reduced the lung wet/dry ratio, pathological changes, and inflammatory responses (Han et al., 2006).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11727062	The Trichoderma plant, known for its cold nature and bitter, astringent taste, contains the small molecule alkaloid homoharringtonine (HHT), which is extracted from its branches and leaves.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Hematologic parameters and molecular analysis of target organs for SCD such as lung were carried out.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hematologic", "parameters", "and", "molecular", "analysis", ...
PMC11711347	Solution 1 was then added dropwise to Solution 2 while stirring continuously with a magnetic stirrer for 30 minutes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Solution", "1", "was", "then", ...
PMC11562028	They exhibited high inhibitory effects on renal cancer A498 cells and renal cell carcinoma.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "They", "exhibited", "high", "inhibitory", "effects", "on", "r...
PMC11502327	The liposomal drug delivery system was tested to improve the conversion performance in Chrysin and the toxic effect of Chr-NiO on SKOV-3 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ ...
PMC6102174	Thus, traditional Chinese herbs with the properties of “clearing heat removing dampness” and “promoting blood circulation and removing blood stasis” are preferable in searching anti-HBV candidates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Less is reported for NK cells, in particular autologous NK cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Less", "is", "reported", "for", "NK", "cells", ",", "in", "particular", "a...
PMC8097906	Briefly, the seeds were obtained from the Agriculture Research Institution (LUFA, Rostock, Germany) and the plants were raised in the University of Rostock (Rostock, Germany).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Eleven patients (22.4%) showed rare scattered mast cells and 33 patients (67.3%) did not show mast cells at all.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	Two (13%) patients had serious AEs (grade 3 febrile neutropenia and grade 3 infection [n=1 each]).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Two", ...
PMC11656657	Non-parametric matched-pairs statistical tests were used to compare the frequency and the absolute number of MDSC among different culture conditions (Friedman test) or between day 0 and each single condition (Wilcoxon matched-pairs signed-rank test).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8345486	The gentle washing of the spheroids after staining consisted of carefully removing the dye-containing buffer from the pellet of the spheroid, adding fresh buffer without dye, and repeating the procedure twice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3931643	In accord, a search of the Oncomine database revealed frequent overexpression of eIF4E mRNA in Burkitt’s Lymphoma, a cancer driven by Myc (Fig. S8).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11618052	The cell viability of compounds 8a–t was examined using the MTT assay after four days of incubation with MCF-10A cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cell"...
PMC10452486	Although Apps et al. contend that HLA-G is a B2m-associated dimer with increased avidity for LILRB1 receptors, Morales et al. showed that normal placental villous cytotrophoblast cells indeed synthesized B2m-free, S-S-bonded HLA-G HC homodimers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8875242	Ledipasvir inhibited RHD123 transport in Caco-2 cells and is suggested to modestly increase the AUC of digoxin in humans .	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ledipasvir", "inhibited", "RHD...
PMC11590005	A social psychology study analysing types of preju-dice highlighted four profiles: truly prejudiced peo-ple, aversive racists, principled conservatives, and modern racists (camouflaged prejudice).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11047729	Silymarin is a substance extracted from milk thistle (Silybum marianum).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Silymarin", "is", "a", "substance", "extracted", "from", "milk", "thistle", "(",...
PMC7987994	Cylindrical samples (20 mm in diameter and 2 mm in height) of Mg_HF_SPS and cuboidal samples (12 × 12 × 3 mm) of Zn_SPS and cylindrical samples (5.5 mm in diameter and 5 mm in height) of Zn0.8 Mg were ground (SiC paper, up to P4000), cleaned and sterilised by immersing into 70% ethanol (2 h) and by subsequent UV exposition (2 h).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11604830	The limit of detection is defined as the minimum proton concentration significantly different from the blank sample (1% low‐gelling agar).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC9429973	For post mortem analysis, PDX cells were reisolated from murine bone marrow and spleen and absolute tumor burden of PDX cells was quantified by flow cytometry of exactly 1/10 of the bone marrow and spleen.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11629192	In our study, three patients (patients 1, 2 and 3) were refractory to the first-line immunotherapy with IVIG and IVMP.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10933092	However, current knowledge of mA modification is mainly based on tRNA studies, and little is known about its role in mRNA and long non-coding RNA (lncRNA) modifications.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10588957	Cell counting kit-8 (CCK-8) was purchased from Dongren Chemical Technology Co., Ltd. (China).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "counting", "kit-8", "(", "CCK-...
PMC11786767	Ki-67 knockdown and CDK1 inhibition also lead to uneven chromosome disjunction between daughter cells, highlighting the critical role of this regulatory mechanism in ensuring accurate chromosome segregation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9031474	For the lysosomes of chronic lymphocytic and acute myeloid leukemia cells, altered membrane composition and expression profiles were observed, leading to higher susceptibility against detergents .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9786247	Asymptomatic, chronically infected cattle primarily shed C. burnetii in milk , and in higher numbers as compared to small ruminants .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Asymptomatic", ",", ...
PMC11320084	Early symptoms of LC patients are atypical and insidious, which can easily lead to missed and misdiagnosis, thereby delaying the best treatment time and increasing the risk of death.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10197932	Data were plotted and analyzed by using GraphPad Prism software version 8.01.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "were", "plotted", "and", "analyzed", "by", "using", "GraphPad", "Prism",...
PMC9964635	Molecules 7f and 7a have shown their anti-cancer effects, especially by affecting Akt and c-lit molecular targets.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Molecules", "7f", "and", "7a", "have",...
PMC11033180	For each sample, 10 μg of proteins were loaded on a 4–12% LDS-NuPage and immunoblotted with Sema5A antibody.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "each", "sample", ...
PMC9592219	Together, these findings indicate that TOP2A is a direct target of miR-22-5p in HCC cells, and the overexpression of miR-22-5p suppresses the invasion and migration of HCC cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11739696	Nanoparticles can be engineered to improve the bioavailability of therapeutic agents, overcome drug resistance, and provide targeted therapy by accumulating in tumor tissues.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC7185206	Additional analyses across the TCGA dataset are reported in Supplemental Figure 1 and Supplemental Tables 1–2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additional", "analyses", "across", "the", "TCGA", "dat...
PMC11754094	Source data In this protocol, PCR-based DNA amplification of the long DNA region (∼10–15 kb) is a critical step.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Source", "da...
PMC11461025	While a number of chemotherapeutic drugs have been approved for treatment of malignancies, the effectiveness varies depending on the type of malignancy and underlying genetic causes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8864075	In this study, we found that baicalein, wogonin, and oroxylin-A were the active compounds of TFAE.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this", "study", ",", ...
PMC3995603	The treatment of AC also reduced the plasma levels of histamine (1.5 fold) and IgE (1.4 fold).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "treatment", ...
PMC11746948	The following primary antibodies were used: GPX4 (1:1,000, A21440, Abclonal), FSP1 (1:1000, 20886-1-AP, Proteintech), SLC7A11 (1:1,000, A2413, Abclonal), ACSL4 (1:1000, 22401-1-AP, Proteintech), Flag (1:1000, F1804, Merck), HA (1:1000, 3724S, CST), APT2 (1:1000, ab151578, Abcam), ZDHHC20 (1:1000, SAB4501054, Sigma-Aldrich), and β-actin (1:3,000, 66009-1-IG, Proteintech).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10587429	However, patient derived xenograft tumor tissues can be digested, and tumor cells isolated, before injecting into the animal orthotopically.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",...
PMC9429973	In the genetic taxonomy, with non-GCB tumors enriched for MCD and BN2 subtype are suitable for the treatment of BTK inhibitor.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", ...
PMC11261875	Note: 2-Deoxyglucose (2DG) serves as an HK inhibitor; however, its principal action within GIST does not primarily involve the curtailment of energy generation through inhibition of glycolysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8740518	Log2 (Fold change) (Log2(FC)) of each metabolite between xenograft and control groups were calculated through dividing their average values.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11413393	a Western blots for indicated proteins in RCC243 cells treated with indicated doses of MS023 for 3 days.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "a", "Western", "blots", "for", ...
PMC11666785	B 3D surface plot of few enlarged sections are also shown.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "B", "3D", "surface", "plot", "of", "few", "enlarged", "sections", "are", "also", ...
PMC11472639	However, there was no change in the frequency of circulating plasma cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "there", "was", "no", "change", "in", "the", "frequenc...
PMC9611901	It is very important that the tannins used have the affinity and ability to react with collagen and have the appropriate size to penetrate the collagen fibres and achieve the desired cross-linking of the structure .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11194678	EMSA assay image of MTOR 5′UTR RNA (20 ng) incubated with 0.4 μM of STAU1 WT or HKΔRBD4 mutant. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "EMSA", "assa...
PMC11297139	The representative images supported by the relevant statistics have been chosen upon three independent preparations with similar outcomes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "representative", "images", "supported...
PMC3164356	For example, immunogenic responses can be induced by glycans harboring N-glycolylneuraminic acid (Neu5Gc), the hydroxylated derivative of the sialic acid N-acetylneuraminic acid (Neu5Ac).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11532793	Another scenario occurs when a multi-transcript gene is lowly expressed but the reads are spread over different ECs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Another", "scenario", "occurs", "when", ...
PMC11666785	In this regard, the integration of light sheet and super-resolution have shown great promise.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this", "regard", ",", "the", "integration", "of", ...
PMC11286266	ATF6α redox status was analysed under basal conditions and following 2-deoxy-D-glucose (2DG) treatment (4 mM, 3 hr) to induce endoplasmic reticulum (ER) stress and ATF6α trafficking.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8567602	In human MRT cancer cell lines, SMARCB1 loss diminishes BAF complex occupancy of many enhancers alongside relative retention of BAF at superenhancers (32).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11759751	Kaplan–Meier survival analysis (D). *	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Kaplan", "–", "Meier", "survival", "analysis", "(", "D", ")", ".", "*" ] } ]
PMC11789597	J and K) NK92 cells were co‐cultured with RPMI 8226 cells in the presence of CXCL10 at the indicated concentrations for 12 h. The apoptotic (Annexin V) cells were determined using flow cytometry.	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC11785489	For Dataset 4, we additionally corrected for batch variable “Chemistry,” and conducted Symphony mapping separately for each tissue.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "Datas...
PMC4270159	Fit normalized data to a sigmoidal dose–response curve.a.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fit", "normalized", "data", "to", "a", "sigmoidal", "dose", "–", "response", "curve.a", "....
PMC6889484	The sensitivity of p24 detection was >1.7 pg/mL. To test whether the P2A tag on A3G-D128K would affect A3G antiviral activity, pHL[WT] (3.3 μg) was co-transfected with pCMV-A3G(DK) or pCMV-A3G(DK)-P2A-eYFP (0.67 μg), and virus was harvested 48 h post-transfection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10204952	As shown in Table 1, 36 secretome genes were upregulated and 21 secretome genes were downregulated, respectively, in responding to S1P treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11604768	Cellular responses to stimuli underpin discoveries in drug development, synthetic biology, and general life sciences.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cellular", "responses", "to", "stimuli", "underpi...
PMC11629143	The 1.8‐fold increase in product titer was far less substantial than the mRNA induction, but yield can be limited by bottlenecks in assembly, processing or secretion .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10237474	After transfection, cells are allowed to grow for a few days before initiation of antibiotic selection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "transfection", ",", "cells", "are", ...
PMC11699178	VEGF-B can bind to FGFR1, inducing the formation of the FGFR1/VEGFR1 complex, which inhibits FGF2-induced Erk activation, thereby suppressing FGF2-driven angiogenesis and tumor growth .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	This may be due to the fact that the number of patients receiving LMWH prophylaxis is low in adult patients receiving PEG-a containing protocol.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC7642379	Moreover, the ratio between missense and synonomous SNVs in all cell lines ranged between 0.866 and 0.879, where the original HEK293 strain had the lowest ratio (Supplementary Fig. S1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", ...
PMC10850553	The increase in the tag count of C5ar1 was not observed in all of the rupture-prone IA samples, which is consistent with the fact that not all rupture-prone aneurysm rupture and that the histological features are diverse in aneurysm lesions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11746942	S1PR3 KO in vitro and in vivo inhibited keratinocyte proliferation and STAT3 phosphorylation, confirming the role of S1PR3 in STAT3 activation and the pathogenesis of psoriasis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6379402	In the main document, for each of breast, prostate, lung, and colorectal cancer, we use the following procedure to assess if the newly prioritized genes resulting from our study could be biomarkers of cancer survival.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8557138	The authors also reported the formation of vessel-like structures consisting of tumor cells parallel to capillary-like structures which later merged to mosaic vessels (Mazio et al. 2018).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10887351	Moreover, SR59230A strongly reduced cancer cell vitality, showing that the β3-ARs antagonism could be a novel therapeutic strategy for ES treatment due to its ability to decrease the antioxidant activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8557138	Further, 3D bioprinting technique can be of significance in developing pre-vascularized grafts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Further", ",", "3D", "bioprinting", "technique", "can", "be", "of", "...
PMC8711270	AdVs now constitute majority of viral vectors in clinical trials with its predominant application as vaccines or in cancer therapies (Bulcha et al., 2021).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	γc cytokines signal through their corresponding receptors, expressed primarily on immune cells (including T cells), that share a common coreceptor, interleukin 2 receptor subunit gamma (IL2RG) that is required for signaling.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Results: Any grade cytokine release syndrome (CRS) developed in 29 patients (93.5%), and grade 3 CRS occurred in three patients (9.7%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11706776	Data were analyzed with Multicycle software.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "were", "analyzed", "with", "Multicycle", "software", "." ] } ]
PMC3019555	The hypoxia inducible factor 1 (HIF-1) is the master regulator of the cell’s response to low-oxygen tension that controls the transcription of >100 genes essential for hypoxic adaptation, angiogenesis, invasion, and tumor progression (Semenza and Wang, 1992; Semenza, 2003).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11714165	By transmission electron microscopy (TEM, HT7700, HITACHI, Japan), the assembled NBD‐F nanoparticles were characterized for size and morphology.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	F. van Rhee, A. Rosenthal, K. Kanhai, R. Martin, K. Nishimura, A. Hoering, D. Fajgenbaum University of Arkansas for Medical Sciences, Little Rock; Cancer Research And Biostatistics, Seattle, United States of America; EUSA Pharma, Hemel Hempstead, United Kingdom; University of Pennsylvania, Philadelphia, United States of America Background: Idiopathic multicentric Castleman disease (iMCD) is a rare, heterogeneous disorder involving multicentric lymphadenopathy, systemic inflammation, and cytokine-driven organ dysfunction.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11775197	Non-coding RNAs (ncRNAs), which comprise the vast majority of the human genome, are a group of non-protein-coding RNAs .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Non-coding", ...
PMC6364197	Data are presented as mean ± standard error.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "presented", "as", "mean", "±", "standard", "error", "." ] } ]
PMC8584319	Statistical significance was set at p < 0.05.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "significance", "was", "set", "at", "p", "<", "0.05", "." ] } ]

PMC9424261

We found that after knocking out HERPUD1, the ubiquitination of GSS was reduced compared with the control group (Fig. 5B).

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PMC7504302

Besides, this model can help to explore novel molecular cues associated with MPM development and eventually enable the design of improved therapeutic strategies .

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PMC11422497

P < 0.05, **P < 0.01.

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PMC11461874

Statistical significance was determined for treatment, time and interaction by two-way ANOVA.

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PMC11577421

Additionally, the interactions were characterized using MST with a Monolith NT.115 instrument (Nanotemper Technologies, Germany).

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PMC11659734

Precipitation limited the range of BPP concentrations selected for the analysis of micronuclei.

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PMC11641630

The authors demonstrated that the fibronectin attachment protein (FAP) of the M. bovis BCG TICE strain binds to fibronectin or integrin α5β1 receptors on the surface of bladder tumor cells , interfering with cell migration.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11599565

Importantly, NCCs represent a unique, multipotent cell type in vertebrates which give rise to neuronal-related cell types including peripheral, enteric neurons and glial cells as well as craniofacial cartilage and bone cells, smooth muscle cells, melanocytes and, importantly, the mesenchyme.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8839885

2-methoxyestradiol (2ME2) is a natural metabolite of the endogenous estrogen hormone 17β-estradiol that is devoid of estrogenic activity .

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PMC9429973

In PBMCs incubated with Brusatol an increase of neoplastic B cells in apoptosis about 68% was observed (Brusatol: 91,9% ± 7,1%; Control: 23,7% ± 4,3%), and of 34% in cells incubated with ML385 (ML385: 57,9% ± 10,2%; Control: 23,7% ± 4,3%).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC6835428

PLL was used in place of the more commonly used PEI to minimize the known toxicity associated with PEI.

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PMC3122064

Antibodies used are listed in Supplementary Methods.

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PMC9739791

The controllable activation was achieved by introducing a coumarin moiety into the oxaliplatin axial position (Figure 9).

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PMC11787651

SWATH DIA scheme and LC gradients.

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PMC9429973

Median guadecitabine exposure was 4 cycles and 3 cycles for TC.

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PMC11047729

Moreover, it can be used as a drug carrier .

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PMC9429973

Summary/Conclusion: Optical Genome Mapping suggest to be very promising diagnostic tool that can complete the study of patients with myelofibrosis, especially in those with non-assessable karyotype.

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PMC11092382

Han et al. used a mouse model of LPS-induced ALI and reported that sophocarpine treatment reduced the lung wet/dry ratio, pathological changes, and inflammatory responses (Han et al., 2006).

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PMC11727062

The Trichoderma plant, known for its cold nature and bitter, astringent taste, contains the small molecule alkaloid homoharringtonine (HHT), which is extracted from its branches and leaves.

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PMC9429973

Hematologic parameters and molecular analysis of target organs for SCD such as lung were carried out.

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PMC11711347

Solution 1 was then added dropwise to Solution 2 while stirring continuously with a magnetic stirrer for 30 minutes.

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PMC11562028

They exhibited high inhibitory effects on renal cancer A498 cells and renal cell carcinoma.

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PMC11502327

The liposomal drug delivery system was tested to improve the conversion performance in Chrysin and the toxic effect of Chr-NiO on SKOV-3 cells.

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PMC6102174

Thus, traditional Chinese herbs with the properties of “clearing heat removing dampness” and “promoting blood circulation and removing blood stasis” are preferable in searching anti-HBV candidates.

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PMC9429973

Less is reported for NK cells, in particular autologous NK cells.

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PMC8097906

Briefly, the seeds were obtained from the Agriculture Research Institution (LUFA, Rostock, Germany) and the plants were raised in the University of Rostock (Rostock, Germany).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Eleven patients (22.4%) showed rare scattered mast cells and 33 patients (67.3%) did not show mast cells at all.

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PMC9429973

Two (13%) patients had serious AEs (grade 3 febrile neutropenia and grade 3 infection [n=1 each]).

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PMC11656657

Non-parametric matched-pairs statistical tests were used to compare the frequency and the absolute number of MDSC among different culture conditions (Friedman test) or between day 0 and each single condition (Wilcoxon matched-pairs signed-rank test).

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PMC8345486

The gentle washing of the spheroids after staining consisted of carefully removing the dye-containing buffer from the pellet of the spheroid, adding fresh buffer without dye, and repeating the procedure twice.

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PMC3931643

In accord, a search of the Oncomine database revealed frequent overexpression of eIF4E mRNA in Burkitt’s Lymphoma, a cancer driven by Myc (Fig. S8).

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PMC11618052

The cell viability of compounds 8a–t was examined using the MTT assay after four days of incubation with MCF-10A cells.

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PMC10452486

Although Apps et al. contend that HLA-G is a B2m-associated dimer with increased avidity for LILRB1 receptors, Morales et al. showed that normal placental villous cytotrophoblast cells indeed synthesized B2m-free, S-S-bonded HLA-G HC homodimers.

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PMC8875242

Ledipasvir inhibited RHD123 transport in Caco-2 cells and is suggested to modestly increase the AUC of digoxin in humans .

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PMC11590005

A social psychology study analysing types of preju-dice highlighted four profiles: truly prejudiced peo-ple, aversive racists, principled conservatives, and modern racists (camouflaged prejudice).

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PMC11047729

Silymarin is a substance extracted from milk thistle (Silybum marianum).

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PMC7987994

Cylindrical samples (20 mm in diameter and 2 mm in height) of Mg_HF_SPS and cuboidal samples (12 × 12 × 3 mm) of Zn_SPS and cylindrical samples (5.5 mm in diameter and 5 mm in height) of Zn0.8 Mg were ground (SiC paper, up to P4000), cleaned and sterilised by immersing into 70% ethanol (2 h) and by subsequent UV exposition (2 h).

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PMC11604830

The limit of detection is defined as the minimum proton concentration significantly different from the blank sample (1% low‐gelling agar).

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PMC9429973

For post mortem analysis, PDX cells were reisolated from murine bone marrow and spleen and absolute tumor burden of PDX cells was quantified by flow cytometry of exactly 1/10 of the bone marrow and spleen.

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PMC11629192

In our study, three patients (patients 1, 2 and 3) were refractory to the first-line immunotherapy with IVIG and IVMP.

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PMC10933092

However, current knowledge of mA modification is mainly based on tRNA studies, and little is known about its role in mRNA and long non-coding RNA (lncRNA) modifications.

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PMC10588957

Cell counting kit-8 (CCK-8) was purchased from Dongren Chemical Technology Co., Ltd. (China).

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PMC11786767

Ki-67 knockdown and CDK1 inhibition also lead to uneven chromosome disjunction between daughter cells, highlighting the critical role of this regulatory mechanism in ensuring accurate chromosome segregation.

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PMC9031474

For the lysosomes of chronic lymphocytic and acute myeloid leukemia cells, altered membrane composition and expression profiles were observed, leading to higher susceptibility against detergents .

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PMC9786247

Asymptomatic, chronically infected cattle primarily shed C. burnetii in milk , and in higher numbers as compared to small ruminants .

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PMC11320084

Early symptoms of LC patients are atypical and insidious, which can easily lead to missed and misdiagnosis, thereby delaying the best treatment time and increasing the risk of death.

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PMC10197932

Data were plotted and analyzed by using GraphPad Prism software version 8.01.

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PMC9964635

Molecules 7f and 7a have shown their anti-cancer effects, especially by affecting Akt and c-lit molecular targets.

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PMC11033180

For each sample, 10 μg of proteins were loaded on a 4–12% LDS-NuPage and immunoblotted with Sema5A antibody.

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PMC9592219

Together, these findings indicate that TOP2A is a direct target of miR-22-5p in HCC cells, and the overexpression of miR-22-5p suppresses the invasion and migration of HCC cells.

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PMC11739696

Nanoparticles can be engineered to improve the bioavailability of therapeutic agents, overcome drug resistance, and provide targeted therapy by accumulating in tumor tissues.

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PMC7185206

Additional analyses across the TCGA dataset are reported in Supplemental Figure 1 and Supplemental Tables 1–2.

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PMC11754094

Source data In this protocol, PCR-based DNA amplification of the long DNA region (∼10–15 kb) is a critical step.

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PMC11461025

While a number of chemotherapeutic drugs have been approved for treatment of malignancies, the effectiveness varies depending on the type of malignancy and underlying genetic causes.

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PMC8864075

In this study, we found that baicalein, wogonin, and oroxylin-A were the active compounds of TFAE.

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PMC3995603

The treatment of AC also reduced the plasma levels of histamine (1.5 fold) and IgE (1.4 fold).

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PMC11746948

The following primary antibodies were used: GPX4 (1:1,000, A21440, Abclonal), FSP1 (1:1000, 20886-1-AP, Proteintech), SLC7A11 (1:1,000, A2413, Abclonal), ACSL4 (1:1000, 22401-1-AP, Proteintech), Flag (1:1000, F1804, Merck), HA (1:1000, 3724S, CST), APT2 (1:1000, ab151578, Abcam), ZDHHC20 (1:1000, SAB4501054, Sigma-Aldrich), and β-actin (1:3,000, 66009-1-IG, Proteintech).

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PMC10587429

However, patient derived xenograft tumor tissues can be digested, and tumor cells isolated, before injecting into the animal orthotopically.

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PMC9429973

In the genetic taxonomy, with non-GCB tumors enriched for MCD and BN2 subtype are suitable for the treatment of BTK inhibitor.

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PMC11261875

Note: 2-Deoxyglucose (2DG) serves as an HK inhibitor; however, its principal action within GIST does not primarily involve the curtailment of energy generation through inhibition of glycolysis.

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PMC8740518

Log2 (Fold change) (Log2(FC)) of each metabolite between xenograft and control groups were calculated through dividing their average values.

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PMC11413393

a Western blots for indicated proteins in RCC243 cells treated with indicated doses of MS023 for 3 days.

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PMC11666785

B 3D surface plot of few enlarged sections are also shown.

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PMC11472639

However, there was no change in the frequency of circulating plasma cells.

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PMC9611901

It is very important that the tannins used have the affinity and ability to react with collagen and have the appropriate size to penetrate the collagen fibres and achieve the desired cross-linking of the structure .

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PMC11194678

EMSA assay image of MTOR 5′UTR RNA (20 ng) incubated with 0.4 μM of STAU1 WT or HKΔRBD4 mutant. (

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PMC11297139

The representative images supported by the relevant statistics have been chosen upon three independent preparations with similar outcomes.

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PMC3164356

For example, immunogenic responses can be induced by glycans harboring N-glycolylneuraminic acid (Neu5Gc), the hydroxylated derivative of the sialic acid N-acetylneuraminic acid (Neu5Ac).

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PMC11532793

Another scenario occurs when a multi-transcript gene is lowly expressed but the reads are spread over different ECs.

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PMC11666785

In this regard, the integration of light sheet and super-resolution have shown great promise.

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PMC11286266

ATF6α redox status was analysed under basal conditions and following 2-deoxy-D-glucose (2DG) treatment (4 mM, 3 hr) to induce endoplasmic reticulum (ER) stress and ATF6α trafficking.

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PMC8567602

In human MRT cancer cell lines, SMARCB1 loss diminishes BAF complex occupancy of many enhancers alongside relative retention of BAF at superenhancers (32).

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PMC11759751

Kaplan–Meier survival analysis (D). *

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PMC11789597

J and K) NK92 cells were co‐cultured with RPMI 8226 cells in the presence of CXCL10 at the indicated concentrations for 12 h. The apoptotic (Annexin V) cells were determined using flow cytometry.

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PMC11785489

For Dataset 4, we additionally corrected for batch variable “Chemistry,” and conducted Symphony mapping separately for each tissue.

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PMC4270159

Fit normalized data to a sigmoidal dose–response curve.a.

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PMC6889484

The sensitivity of p24 detection was >1.7 pg/mL. To test whether the P2A tag on A3G-D128K would affect A3G antiviral activity, pHL[WT] (3.3 μg) was co-transfected with pCMV-A3G(DK) or pCMV-A3G(DK)-P2A-eYFP (0.67 μg), and virus was harvested 48 h post-transfection.

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PMC10204952

As shown in Table 1, 36 secretome genes were upregulated and 21 secretome genes were downregulated, respectively, in responding to S1P treatment.

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PMC11604768

Cellular responses to stimuli underpin discoveries in drug development, synthetic biology, and general life sciences.

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PMC11629143

The 1.8‐fold increase in product titer was far less substantial than the mRNA induction, but yield can be limited by bottlenecks in assembly, processing or secretion .

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PMC10237474

After transfection, cells are allowed to grow for a few days before initiation of antibiotic selection.

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PMC11699178

VEGF-B can bind to FGFR1, inducing the formation of the FGFR1/VEGFR1 complex, which inhibits FGF2-induced Erk activation, thereby suppressing FGF2-driven angiogenesis and tumor growth .

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PMC9429973

This may be due to the fact that the number of patients receiving LMWH prophylaxis is low in adult patients receiving PEG-a containing protocol.

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PMC7642379

Moreover, the ratio between missense and synonomous SNVs in all cell lines ranged between 0.866 and 0.879, where the original HEK293 strain had the lowest ratio (Supplementary Fig. S1).

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PMC10850553

The increase in the tag count of C5ar1 was not observed in all of the rupture-prone IA samples, which is consistent with the fact that not all rupture-prone aneurysm rupture and that the histological features are diverse in aneurysm lesions.

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PMC11746942

S1PR3 KO in vitro and in vivo inhibited keratinocyte proliferation and STAT3 phosphorylation, confirming the role of S1PR3 in STAT3 activation and the pathogenesis of psoriasis.

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PMC6379402

In the main document, for each of breast, prostate, lung, and colorectal cancer, we use the following procedure to assess if the newly prioritized genes resulting from our study could be biomarkers of cancer survival.

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PMC8557138

The authors also reported the formation of vessel-like structures consisting of tumor cells parallel to capillary-like structures which later merged to mosaic vessels (Mazio et al. 2018).

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PMC10887351

Moreover, SR59230A strongly reduced cancer cell vitality, showing that the β3-ARs antagonism could be a novel therapeutic strategy for ES treatment due to its ability to decrease the antioxidant activity.

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PMC8557138

Further, 3D bioprinting technique can be of significance in developing pre-vascularized grafts.

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PMC8711270

AdVs now constitute majority of viral vectors in clinical trials with its predominant application as vaccines or in cancer therapies (Bulcha et al., 2021).

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PMC9429973

γc cytokines signal through their corresponding receptors, expressed primarily on immune cells (including T cells), that share a common coreceptor, interleukin 2 receptor subunit gamma (IL2RG) that is required for signaling.

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PMC9429973

Results: Any grade cytokine release syndrome (CRS) developed in 29 patients (93.5%), and grade 3 CRS occurred in three patients (9.7%).

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PMC11706776

Data were analyzed with Multicycle software.

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PMC3019555

The hypoxia inducible factor 1 (HIF-1) is the master regulator of the cell’s response to low-oxygen tension that controls the transcription of >100 genes essential for hypoxic adaptation, angiogenesis, invasion, and tumor progression (Semenza and Wang, 1992; Semenza, 2003).

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PMC11714165

By transmission electron microscopy (TEM, HT7700, HITACHI, Japan), the assembled NBD‐F nanoparticles were characterized for size and morphology.

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PMC9429973

F. van Rhee, A. Rosenthal, K. Kanhai, R. Martin, K. Nishimura, A. Hoering, D. Fajgenbaum University of Arkansas for Medical Sciences, Little Rock; Cancer Research And Biostatistics, Seattle, United States of America; EUSA Pharma, Hemel Hempstead, United Kingdom; University of Pennsylvania, Philadelphia, United States of America Background: Idiopathic multicentric Castleman disease (iMCD) is a rare, heterogeneous disorder involving multicentric lymphadenopathy, systemic inflammation, and cytokine-driven organ dysfunction.

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PMC11775197

Non-coding RNAs (ncRNAs), which comprise the vast majority of the human genome, are a group of non-protein-coding RNAs .

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PMC6364197

Data are presented as mean ± standard error.

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PMC8584319

Statistical significance was set at p < 0.05.

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