Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
Community
1
PMCID
string
Sentences
string
ner
list
PMC11759543
5637 and BFTC 905 cells were seeded at 3 × 10 cells and 4 × 10 cells, respectively, in a 6-cm dish and cultured for 24 h to reach 70–80 % cell confluence.
[ { "tags": [ "B-CellLine", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC10170482
These data confirmed our observations revealing that the soft 3D microenvironment promotes marked ΔΨm depolarization, making cells more sensitive to various depolarizing treatments.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11759543
Fig. 5Fig.
[ { "tags": [ "O", "O", "O" ], "tokens": [ "Fig.", "5Fig", "." ] } ]
PMC11257203
This study aimed to investigate the protective effects of curcumin against indomethacin-induced genotoxicity.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "study", "aimed", "to", "investigate", "the", "protective", "effects...
PMC11716858
It can be concluded that COX‐2 protein can serve as a potential blood‐based biomarker for early detection and can be a good platform for therapeutic intervention for AD.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7553912
P < 0.05 compared with day 0.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", "<", "0.05", "compared", "with", "day", "0", "." ] } ]
PMC4270159
g. Collect the lysate/protein sample and store at −20°C or −80°C for later use.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "g.", "Collect", "the", "lysate/protein", ...
PMC11612508
There was a significant difference (P < 0.05) in the swelling and loading rates at pH 7.4 and 4.5.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "was", "a...
PMC11400680
Earlier the era of deep learning, most of the research for microscopic cell segmentations used conventional image segmentation methods: intensity-based segmentation such as thresholding (7), region-based segmentation such as contour detection using snake (8,9) or level sets methods (10), and clustering based segmentation (9,11).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10253973
In Figure 2, molecular targets that are important in fighting cancer cells are shown.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "Figure", "2", ",", "molecular", "targets", "that", ...
PMC4839679
We created complementary cell lines using lentiviral knockdown of PBRM1 in A498 and Caki1 and the re-expression of PBRM1 in A704 and Caki2 using lentiviral re-expression of PBRM1 with a tet-inducible vector (Fig 1D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", ...
PMC11015054
Immunofluorescence results of HL‐60 cells cocultured with HL‐60 cells from METTL5‐sh and METTL5‐NC groups showed MPO/H3 expression in METTL5‐NC group was higher than METTL5‐sh group, consistent with tumor tissue results (Figure 5Q–T).
[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11055510
The regulation of circMAN1A2 on the phosphorylation level of TAK1 involves the miR-135a-3p/IL1RAP axis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "regulation", "of", "circMAN1A2", "on", "the", "phosphorylation"...
PMC11422497
OD, Optical Density.
[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "OD", ",", "Optical", "Density", "." ] } ]
PMC11682172
The solid line across the box indicates the median value.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "solid", "line", "across", "the", "box", "indicates", "the", "median", "value", "." ...
PMC9429973
The primary endpoint was CR (as best response) rate by PET/CT assessed by Independent Review Committee using standard response criteria (Cheson et al. 2007).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Patients treated with remdesvir only had similar outcomes as those treated with remdesvir and plasma (15% vs. 19% respectively).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patient...
PMC7369657
The experimental design and procedures were approved by the Institutional Ethical Committee for Animal Care and Use of Peking University First Hospital, People's Republic of China (the ethical code: J201808).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9964654
In order to assess the loading contents of the resulting BCMs-[Au(cdc)2] (formulations AS1–AS5), known amounts of the micelles were disassembled using acetonitrile followed by UV-Vis analysis of the solubilized contents (Figure 3).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11279397
The drug has been reported to interact with ACE 2, DPP4, COMT, TUBGCP3, CENPF, BRD 2 and HMOX 1 host proteins involved in antiviral mechanisms such as viral entry, replication, immune response and antioxidant activity against SARS-CoV-2 based on network pharmacology, virtual screening, molecular docking and molecular dynamics methods .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11476666
At the protein levels, both stemness markers were significantly reduced in the preformation conditions after treatment with DHS or RSV (Figure 4e–g).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11547972
The effectiveness of the amygdalin–SFN combination was determined using the Bliss independence model.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "effectiveness", "of", "the", "amygdalin", "–", "SFN"...
PMC11361748
Immunostaining of tissue sections for phospho-PKCα evidenced a weak signal in WT and Krt17 null epidermis at baseline (see Fig 4A and 4B).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11787355
TCGA data were downloaded through the package TCGAbiolinks (2.28.4).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TCGA", "data", "were", "downloaded", "through", "the", "package", "TCGAbiolinks", "(", ...
PMC9429973
Image: Summary/Conclusion: This post hoc analysis of PRINCE trial data revealed that a substantial proportion of patients achieved good or complete hematologic response to PEG after 26 weeks.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10568263
Subsequently, the solution was heated in an oven at 140 °C for 1 h. The as-prepared precipitates were obtained by centrifugation and washed with ethanol and DI water several times.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11782780
GAPDH was utilized as an internal reference for EBF3, and U6 for miR-301b-3p.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GAPDH", "was", "utilized", "as", "an", "internal", "reference", ...
PMC11591038
Currently less well understood, these are pivotal issues that also deserve attention besides the roles of HIF-1 in AD.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Currently", "less", "well", ...
PMC11387401
This full interactome revealed a total set of 1467 HIV-1 protein–host RNA interactions, with Nucleocapsid being the HIV-1 protein that possesses the highest host RNA binding capacity with 857 interactions, followed by Rev (289), Pol (73) and Gag (73) (Fig. 1C).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11585254
Data were fit by nonlinear regression [log[agonist]versus response (three parameters)] using GraphPad PRISM.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "were", "fit", "by", "nonlinear", "r...
PMC7823217
Therefore, creating heterogenous and physiologically related 3D cancer tissue constructs is expected to expand our understanding of the effects and mechanisms of chemotherapeutic agents on the cancer growth, progression, metastasis and therapy response .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11777207
We next assessed chemokine-mediated migration of the transduced BMDCs by using the in vitro transwell assay described above (Fig. 4A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "next",...
PMC10291556
The data are shown as MEAN of 4–5 independent measurements.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "data", "are", "shown", "as", "MEAN", "of", "4–5", "independent", "measurements", "....
PMC8540692
Similar effects were reported for NaBu and its combination treatment with CCM in A-172 cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Similar", "effects", "were", "reported", "for", "NaBu", ...
PMC11711127
Linette et al. (31), 2019 show that immunological ignorance of clonal neoantigens leads to ineffective T cell immunity against melanoma.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Linette...
PMC11496491
Gene SymbolAssociated cell or tissueDescriptionCATG00000038258.1–At least 1 of the 10 top ranked transcript is CPAT coding and max ORF size > = 300PAK6Caudate nucleusp21 (RAC1) activated kinase 6IGFL1Sebaceous glandIGF like family member 1PPP1R12Aneutrophilprotein phosphatase 1 regulatory subunit 12ALMF1Substantia nigralipase maturation factor 1CASP14Mammary gland epithelial cellcaspase 14CATG00000036350.1–At least 1 of the 10 top ranked transcript is CPAT coding and max ORF size > = 300ARHGAP30EosinophilRho GTPase activating protein 30UMOD–uromodulinHAPLN2Nervous systemhyaluronan and proteoglycan link protein 2KRT9Thymuskeratin 9ZFP57Chorionic membrane mesenchymal stem cellZFP57 zinc finger proteinCNEP1R1NeutrophilCTD nuclear envelope phosphatase 1 regulatory subunit 1METTL14Middle temporal gyrusMethyltransferase like 14MTRNR2L5Extra ocular muscleMT-RNR2 like 5DUSP12–Dual specificity phosphatase 12OR9K2–Olfactory receptor family 9 subfamily K member 2APLNEndothelial cellApelinMKRN3Neuron projection bundleMakorin ring finger protein 3OR2M7–Olfactory receptor family 2 subfamily M member 7 The top 20 down-regulated genes with the most significant differences.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11774112
In addition, in vivo results indicated that Co-PHRD micelles can significantly inhibit tumor growth without causing significant damage to major organs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "additi...
PMC11788920
E and F) Cell viability studies in cells targeted with RNP1, RNP2, RNP3, RNP1 + RNP2, or with RNP2 + RNP3.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10914904
1The human vault RNAs biogenesis.
[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "1The", "human", "vault", "RNAs", "biogenesis", "." ] } ]
PMC4485648
SFN is a cancer-chemopreventive isothiocyanate found in cruciferous vegetables, namely in broccoli.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SFN", "is", "a", "cancer-chemopreventive", "isothiocyanate", "found", "in", ...
PMC10996034
It is important to identify novel promising gene targets associated with Taxol resistance for EOC drug therapy, targeted elimination of drug resistance, and improvement of treatment efficacy and patient prognosis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11387401
Kutluay et al, (2014) performed crosslinking immunoprecipitation (CLIP) sequencing to assess RNA binding by Gag.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Kutluay", "et", "al", ...
PMC9895440
d Nuclear translocation measured by image cytometry of NFATc2 in Teff upon anti-CD3/28 stimulation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "d", "Nuclear", "translocation", "measured", "by", "image", "cytometry"...
PMC9429973
Most CRS events were associated with the first full dose.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Most", "CRS", "events", "were", "associated", "with", "the", "first", "full", "dose", "." ...
PMC11139449
Global market projections indicate that the biopharmaceutical industry is expected to reach approximately $389 billion by 2024 ( 1 ).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Global", "market", ...
PMC10547921
NMR structural data from Klaus Weisz's team confirmed the strong binding of PBD heterozygotes to small grooves of DNA double strands, forming covalent bonds between the PBD moiety and the outer ring guanine amino group.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11420784
Autophagy is a housekeeping process that maintains cellular homeostasis .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Autophagy", "is", "a", "housekeeping", "process", "that", "maintains", "cellular", "homeostasis", "." ]...
PMC11531744
After pretreatment, slides were loaded with the primary antibody (1:200) overnight at 4 °C.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "pretreatment", ",", "slides", ...
PMC10178190
Thus, 2HE2 is active in restoring platinum sensitivity to OC cells exposed to MS-5- and TA HS-5-derived CM.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Thus", ",", "2HE2", "is"...
PMC11127909
The binding between Flag-tagged EFHD1 mutants and ANT3 was analyzed by IP/IB, N = 3.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "binding", "between", "Flag-tagged", "EFHD1", "m...
PMC11541241
Additionally, heterologous overexpression of AWR5 in yeast induced massive transcriptomic changes that mimicked those caused by RAP.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "heterologous", "overexp...
PMC10936243
Because sometimes if there is under-pad also it may tear or overturn” [D122]. “
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Because", "sometimes", "if", "there", "is", ...
PMC11388384
We noted that population fraction implied by the transition matrix was slightly different than the observed instantaneous population fraction estimated by ExTrack or SaSpt, which reflects the fact that ExTrack did not converge to a global maximum likelihood estimation for every transition rate.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11089031
Using TCGA ccRCC RNA-seq data, we analyzed the expression of ZNR692 in the ccRCC cohort (A, B).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Using", "TCGA", "...
PMC11803918
Our work introduces a promising therapeutic approach for efficiently and safely treating superficial carcinomas like melanoma.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Our", "work", "introduces", "a", "promising", "therape...
PMC10988808
F H&E and fluorescence images of Xenograft tumor labeled by DAPI, Tunel, Caspase3 CCDC25 affects the hippo pathway by promoting YAP phosphorylation through LATS1.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10988808
The mice were anesthetized with isoflurane, and a cell suspension (100 μL) was injected subcutaneously into the right back of each mouse .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC8414691
Scale bar = 5 μm.
[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", "=", "5", "μm", "." ] } ]
PMC11739504
Red ovals indicate KAT2B; green circles indicate IFT-B particles; blue circles indicate SMO; light grey circles indicate α-tubulin.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Red", "ovals", "i...
PMC11747885
To evaluate the selectivity of the identified active Rlig1 inhibitors, we expressed and purified the hLig1 adapted from a published protocol.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "evalua...
PMC11461874
This is also supported by our results showing that TRAF7 overexpression counteracts DBP overexpression in terms of the amplitudes of the clock gene expression (Fig. 5c).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11585994
We measured the weight of PDX mice one week after treatment with nanoparticles.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "measured", "the", "weight", "of", "PDX", "mice", "one", "week",...
PMC11269792
GIST accounts for 1 %‒3 % of gastrointestinal tumors.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GIST", "accounts", "for", "1", "%", "‒3", "%", "of", "gastrointestinal", "tumors", "." ...
PMC11721295
A second group, L-iKRAS OFF mice, was given ad-Cre for 17 weeks before dox withdrawal for 1, 2, or 4 weeks (Figure 1C).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10291556
Here, we describe the synthesis and biological properties of new prodrugs that combine two bioactive constituents: [Pt(1S,2S-diaminocyclohexane)(5,6-dimethyl-1,10-phenanthroline)(X)(Y)] (Pt56MeSS) with one or two axially coordinated DCFs (Figure 1).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
A CR was noted in 61% of cases.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "CR", "was", "noted", "in", "61", "%", "of", "cases", "." ] } ]
PMC9504875
The innate immune system is the first line of host defense against virus infection.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "innate", "immune", "system", "is", "the", "first", "line"...
PMC11680562
This study explores the synergistic therapeutic potential of green-synthesized CuO NPs combined with 5-Fu in a gel formulation for targeted anticancer activity against HeLa cervical cancer cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", ...
PMC9429973
All pts presented with Ann Arbor stage IV disease.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "pts", "presented", "with", "Ann", "Arbor", "stage", "IV", "disease", "." ] } ]
PMC9429973
Aims: To study the role of the weakening of the platelets procoagulant activity in the development of hemorrhagic syndrome.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "To", "stu...
PMC8348645
The pro-apoptotic BAX gene showed increased gene expression following treatment with W. somnifera, while BCl2, the anti-apoptotic gene, was downregulated, indicating that this plant extract induced inhibition of the proliferation of the cancer cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11635087
Cells were routinely subcultured every 3 to 4 days by dilution to a cell density of approximately 2 × 10 cells mL in the 100 mm dish.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11469524
After 5 minutes centrifugation (500xg, 4°C) the cells were washed once.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "5", "minutes", "centrifugation", "(", "500xg"...
PMC11488203
Fig. 5The role of miRs on the viability of different cancer cell lines.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "5The", "role", "of", "miRs", "on", "the", "viability", "of", ...
PMC11740207
Recent experimental evidence indicates that CSCs can originate from malignantly transformed very small ELSCs (VSELSCs) (Bhartiya et al., 2023b).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973
We cannot preclude the possibility of a biclonal disease caused by mutation of CALR and some other unknown Ph-MPN-association mutation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "can", "not"...
PMC3675084
Our results are consistent with previous reports that cells that die through mitotic catastrophe usually do not show DNA ladder formation or DNA breaks that are detectable by TUNEL staining , , , .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11718109
EM images depicting the presence of classical SSVs with clear PSDs (B) and a more heterogenous pool of vesicles lacking PSDs (C) in axonal terminals.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11194678
Right: Line plot of STAU1 and RNA fluorescence intensities in indicated box regions. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Right", ":", "Line", "plot", "of", "STAU1", "and", "R...
PMC4659567
However, an integral intensity ratio (9: 1) was found to be inverse as compared with 2, and did not change in time, which showed that equilibrium between free GSH and Ru–SG adduct is reached rapidly.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9592219
The moderate or high expression of TOP2A coexpressed genes was identified based on the screening criteria (P < 0.001, |r| > 0.5).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11755624
UCA1 is positively correlated with pro-inflammatory mediators such as IL-6 and CXCL1.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "UCA1", "is", "positively", "correlated", "with", "pro-inflammatory", "mediators", "suc...
PMC11634027
Conversely, ds, ds, ds, ds and ds lines all had five tarsal segments, as observed in control flies ds and w (Fig. S3I-L,N,O).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9780037
This is a frequently overlooked issue.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "is", "a", "frequently", "overlooked", "issue", "." ] } ]
PMC6835428
Although HeLa spheroids are not directly pertinent to OC study, these data are encouraging for further tests in OC spheroids.
[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Although", "He...
PMC10154881
Tumor growth was significantly suppressed in both models after treatment with rMV‐SLAMblind (Figure 2C,D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tumor", "growth", "was", "significantly", ...
PMC10761218
The methanolic extracts derived from the root of W. somnifera were found to lack satisfactory cytotoxic activity against both HepG2 and L929, as evidenced by IC50 values exceeding 100 μg/mL. This observation is consistent with prior research indicating that W. somnifera root extract has a minimal cytotoxic impact on L929 cells .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "...
PMC11748618
Haplotypes are represented if they were present in at least 1% of samples.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Haplotypes", "are", "represented", "if", "they", "were", "present", ...
PMC8357004
Asterisks (*) demonstrate significant differences between treated and untreated control groups.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Asterisks", "(", "*", ")", "demonstrate", "significant", "differences", "be...
PMC9429973
Only variants included into 4 and 5 categories were taken into account.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Only", "variants", "included", "into", "4", "and", "5", "categories", "were", ...
PMC11585254
Taken together, the major determinants specifying β-arrestin recruitment to CXCR5 reside within a phospho-site cluster located at the extreme distal region of the CT.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC7022782
Both compacted and dispersed cells (not confluent growth) presented a normal cytoplasmic content and morphology, without any dots and green structures.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11804588
On the other hand, FOODIE alone cannot yet confidently identify the full spectrum of transcription factors bound throughout the genome, because our current catalog of TFs with known sequence specificity is still incomplete, and many transcription factors share similar DNA binding motifs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11361748
Data reported as mean ± SEM.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "reported", "as", "mean", "±", "SEM", "." ] } ]
PMC8609870
a Showed that the top 10 enriched GO pathways of DELs were sorted by significance in biological process (BP), cellular component (CC) and molecular function (MF), respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11525293
Moreover, Len at very high doses has been shown to induce ACE2 downmodulation through a post-translational mechanism .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "Len", "at", "very", ...
PMC11787651
The color spectrum from dark blue to dark red represents varying expression levels from low to high.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "color", "spectrum", "from", "dark", ...
PMC10958426
Wei Cao: Writing – review & editing, Writing – original draft, Visualization, Software, Methodology, Formal analysis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Wei", "Cao",...
PMC11001582
A grip strength meter (Bioseb) was used to measure forelimb and hindlimb grip strength.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "grip", "strength", "meter", "(", "Bioseb", ...
PMC9622879
is the energy cost which all buying homes must pay for EP.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "is", "the", "energy", "cost", "which", "all", "buying", "homes", "must", "...