Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
Community
1
PMCID
string
Sentences
string
ner
list
PMC11753435
The plot of Hamming distance as we varied k is depicted in Fig. 2A.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "plot", "of", "Hamming", "distance", "as", "we", "varied",...
PMC6642070
The patients were glycolytic defective, which prevents energy production, similar to other inherited metabolic myopathies.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "patients", "were", "glycolytic", "defectiv...
PMC11409031
The genetic profile was displayed utilizing the software 'maftools'.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "genetic", "profile", "was", "displayed", "utilizing", "the", "software", "'", ...
PMC11762280
p-MLKL phosphorylated MLKL.
[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "p-MLKL", "phosphorylated", "MLKL", "." ] } ]
PMC11194678
A–C) Representative confocal images showing coexpression of mCherry-HTTexon1 Q72 with control PEGFP-C3, EGFP-STAU1 WT, or 5KE mutant in U251 cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ],...
PMC9429973
Overall survival (OS) was defined as time from index until death or censoring and assessed by Kaplan–Meier analysis; landmark survival was defined as the proportion of patients who survived at a given point.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Mean age was 63 years and 55% were male.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mean", "age", "was", "63", "years", "and", "55", "%", "were", "male", "." ] } ]
PMC11806182
To explore potential causal relationships between AURKA gene expression and POCS, UCEC, we performed a two-sample Mendelian randomization (MR) analysis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973
In a phase 2, open-label trial of mitapivat in adults with α- or β-non–transfusion-dependent (NTD) thalassemia (NCT03692052), 80% (16/20) of patients (pts) met the primary endpoint of a hemoglobin (Hb) response (≥1.0 g/dL increase from baseline [BL] at ≥1 assessments between Weeks (Wks) 4–12, inclusive).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11551844
The presence of olefinic protons was observed at δH 5.02, δH 5.15 and δH 5.33.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "presence", "of", "olefinic", "protons", "was", ...
PMC9429973
The study was registered on ClinicalTrials.gov (NCT04160052).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "study", "was", "registered", "on", "ClinicalTrials.gov", "(", "NCT04160052", ")", "." ] } ]
PMC8839885
Solvent-treated samples were incubated with 0.1% (w/v) dimethyl sulfoxide.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Solvent-treated", "samples", "were", "incubated", "with", "0.1", "%", "(", "w/v"...
PMC11672142
Each of the intermediates was confirmed by H nuclear magnetic resonance (NMR) spectroscopy (peaks are detailed in the experimental section and spectra are included in Supporting Information Figures S2–S4).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3888431
It was shown that a single assembly, even guided by a draft genome, is not sufficient to construct a complete set of transcripts.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9776316
Nonetheless, we also used the Western blot to monitor the ATM-dependent signaling event profiling and found a consistently increased level of phosphorylation of ATM and CHK2 in the XRCC4 knockdown cells relative to control cells upon the treatment of cisplatin, further suggesting that XRCC4 knockdown sensitizes the cisplatin through aggravating the DNA damage (Figure 3c,d).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11597291
The nCGO-PEG particles caused less than 10% of programmed cell death at 48 h, while a slightly increased apoptosis rate was induced by the nCGO control samples.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10040136
A P-value < 0.05 was considered significant.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "P-value", "<", "0.05", "was", "considered", "significant", "." ] } ]
PMC11618052
It is 4-fold less potent than compound 8g, the methoxy derivative.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "4-fold", "less", "potent", "than", "compound", "8", "g", ...
PMC9429973
Summary/Conclusion: Our epidemiological and clinical data are globally similar to reported studies except for systemic symptoms affecting only 20 % of cases and advanced stages, which are less frequent (20-30%) in the literature.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8875242
The medium was changed every other day, during which the transepithelial electrical resistance (TEER) across the cell monolayers was measured using a Millicell-ERS instrument (Millipore Corporation, Bedford, MA, USA) .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11637276
Cells were seeded into a 12-well plate and incubated overnight to achieve confluency.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "seeded", "into", "a", "12-well", "plate", "and", "in...
PMC10470467
Correlation analysis of the expression levels of 6 key genes with immune checkpoints (C) and clinical features (D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Correlation", ...
PMC11078693
Place the 25 mm cover glass with the labeled side up at the bottom of a flat bottom 50 mL tube.b.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Place", "the", "2...
PMC5839394
Several proteins can be used as markers to study autophagic flux: in particular, during autophagy, ATG proteins (eg ATG5 and ATG7) and Beclin -1, have an essential role in the autophagosome formation .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11621493
Accordingly, we detected Pla2g4d gene expression in murine testis, stomach, and epidermis as well as lower levels in the eye and brain (Fig. 7A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11449273
All tissue culture reagents were purchased from Gibco unless otherwise stated.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "tissue", "culture", "reagents", "were", "purchased", "from", "Gibco", "unless", ...
PMC8916024
Moreover, studies have reported that it also plays an important role in heptoprotective.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "studies", "have", "reported", "that", "it", "al...
PMC11521786
The image displays lungs extracted from immunized or control mice 3 weeks later.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "image", "displays", "lungs", "extracted", "from", "immunized", "or",...
PMC8916024
The V3–V4 region of 16s rRNA gene was amplified by PCR using universal primers 341F: CCTACGGGNGGCWGCAG and 806R: GGACTACHVGGGTATCTAAT (Guo et al., 2017).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11680391
The questionnaire was primarily based on the Likert scale (1932) , with the following options: strongly agree, very agree, agree, neither, disagree, very disagree, and strongly disagree.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Sokal and ELTS scores had no influence on FIT since 44.4% (4pts) of intermediate, 33.3% (3pts) of low and 2 of high risk relapsed vs 37.5% (6pts) of intermediate, 25% (4pts) of low and 4 of high risk in FIT, an influence of gender since 77.7% of relapses were men, age and even depth of MMR are all potential factors for cessation but the results in our cohort.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10482220
In each case, hybridization with oligo-dT probe was included to positively identify SGs. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "each", "case", ",", "hybridization", "with", "oligo-d...
PMC11699178
P < 0.05, **P < 0.01, ***P < 0.001 Validation of the upstream–downstream relationships of HIF-1α, VEGF-B, and FGF2/FGFR1.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7917457
The groups of mice receiving saline or the nonreplicating Ad5/3Luc1 showed similar increases in tumor volumes, and by day 25 after the start of the treatment, the average volumes of the tumors had reached approximately 10× the initial volumes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11519788
Above data indicated that SPOP depletion promoted the secretion of macrophage-derived IL-6 into TME, thereby contributing to the escalation of UBC cell proliferation and the induction of cancer stemness.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11753435
Gaussian distributions centered around the ESM-2 embeddings of naturally occurring peptides are sampled and then decoded back to amino acid sequences.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gaussian", "distributio...
PMC10748106
Structurally, iridoids are atypical monoterpenoids and are generally described as cyclopentane [C]-pyran.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Structurally", ",", "iridoids", "are", "atypical", "monoterpenoids", "and", ...
PMC8873393
E Representative images of MRC5_VA cells at the indicated recovery time after 10 J/m UV-C irradiation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "E", "Representative", "images", "of", "MRC5_VA", "cell...
PMC11696659
We showed that a cohort of patients diagnosed with lung cancer presented generally shorter telomeres compared with the control cohort without cancer (including patients at high risk without cancer and healthy individuals).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8427838
E Western blot analysis of CRISPR-Cas9 mediated knockout of moesin in RKO cells and RKO cells expressing TMIGD1.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "E", "Western", "blot", "an...
PMC5363531
A further PEM alone administration (72 hours), without dasatinib pretreatment, was also performed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "further", "PEM", "alone", "administration", ...
PMC11621493
To produce lentiviral particles encoding mPLA2G4D, HEK293T cells (CRL-3216, ATCC) were seeded into 6-well plates (1 × 10 cells/well).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC11786767
GFP serves as a control that is insensitive to Ki-67 knockdown.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GFP", "serves", "as", "a", "control", "that", "is", "insensitive", "to", "Ki-67", ...
PMC10203589
Interestingly, the expression of FGF18 at mRNA level detected in tumors of xenograft models by qRT-PCR was positively correlated with the antitumor effect of FP-1039, and surface plasmon resonance (SPR) spectroscopy showed that FP-1039 could be bound to FGF18 with high affinity (129).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11637276
These data indicate that Matrigel is first delivered to early endosomes and subsequently to lysosomes for degradation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "data", "indicate", "that", "Matrigel", ...
PMC9429973
Methods: 60 patients with B-ALL received CD19-CAR-T treatment in Hebei Yanda Lu Daopei Hospital in 2020 were randomly selected.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Methods", ":", "60", "...
PMC11407042
CRITICAL: Seed cells when confluence reaches 80%–90%.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CRITICAL", ":", "Seed", "cells", "when", "confluence", "reaches", "80%–90", "%", "." ] } ]
PMC11621493
The mS370A mutant was used as negative control. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mS370A", "mutant", "was", "used", "as", "negative", "control", ".", "(" ] } ]
PMC11618052
This study conducted a thorough computer docking analysis to determine the binding relationships between chemicals 8f, 8g, 8h, 8j, and 8l and EGFR-TK.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10196713
The results of flow cytometric analysis were analyzed by FlowJo (version 10.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", "of", "flow", "cytometric", "analysis", "were", "analyzed"...
PMC9429973
Particularly butyrate, a short chain fatty acid (SCFA) derived from the microbial fermentation of dietary fibers, affects immune cell proliferation, activation, apoptosis and cytokine expression.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11190238
IGV Snapshots of an epithelial (KRT19; 5.3 kilobase locus) and mesenchymal (COL5A2; 157 kilobase locus) gene demonstrating concordant compartment and expression dynamics is shown in the middle.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10114490
B Representative phase contrast images of iHDF and iHDF-T at PD (just derived; approximately PD24), PD (PD 30–40) and PD (PD 100–110).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11128598
Chloroquine inhibits cell proliferation in a variety of human solid tumor cell lines.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Chloroquine", "inhibits", "cell", "proliferation", "in", "a", "variety", "o...
PMC10582049
Expression of canonical genes associated with CAFs, smooth muscle cells, and pericytes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Expression", "of", "canonical", "genes", "associated", "with", "CAFs",...
PMC11721587
Expression of Fu (C765 > Fu) in fu wing discs restored Hh target gene expression and down-regulated Ci in A-compartment cells near the A/P boundary (Fig. 1F and fig. S1F), suggesting that C765 > Fu converted Ci into labile Ci in the absence of endogenous Fu.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10582828
The presence of furin cleavage sites has fundamental implications for the pathogenicity of SARS, MERS, and SARS-2.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "presence", "of", "furin", ...
PMC8140214
Results are given as mean±SD (n=4). *
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", "are", "given", "as", "mean±SD", "(", "n=4", ")", ".", "*" ] } ]
PMC7642379
The observed enrichment of cell adhesion GO-terms (GO:0,007,156 and GO:0,098,742) amongst genes with common high/moderate impact SNPs unique to progeny cell lines compared to HEK293 cells also supported common genomic alterations in progeny cell lines involved in cell adhesion.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellL...
PMC9503541
Mass features in the form of [M+H]+ adducts were collected using tolerance values of 0.01 and 0.025 for MS1 and MS2, respectively, with peak heights of 1000 and mass slice widths of 0.1 Da.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8382973
We collected pairs of RL and CVL samples from 48 NZW rabbits and simultaneously treated the extracted DNA and sequenced 16S ribosomal RNA genes, providing a strong opportunity for comparative evaluation of these different mucosal compartments.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11786600
It may be related to the longer inflammatory period and immune disorders in diabetic wounds, as well as the persistent elevation of pro-inflammatory factors in the first three groups.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11615743
The L‐DNA phosphoramidite monomer reagent was then added, and the synthesis procedure continued until the end of the procedure.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "L‐DNA", "phosphoramid...
PMC10878518
Data are expressed as mean values ± SD of independent experiments (n = 5). (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "expressed", "as", "mean", "v...
PMC11741906
Future research should focus on functional validation, in vivo experiments and patient-derived samples.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Future", "research", "should", "focus", "on", "functional", "validatio...
PMC9429973
On the transcriptomic level, samples from the profile II were less capable of activating p53 target genes upon doxorubicin treatment, thus resembling TP53-mutant cells, whereas proper p53 signaling was triggered in profile I. Consistently, induction of the studied downstream effector genes CDKN1A, BAX, BBC3 and GADD45 after doxorubicin treatment was lower in profile II than in profile I samples but still higher than in TP53 mutants.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11052306
However, no experiment was carried out with an identical quantity of copper in all cases .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "no", "experiment", "was", "carried", ...
PMC11779960
In fact, diagnosis of TCL often uses clonotypic assessment of TCRγ and TCRβ using multiplexed PCR amplification.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "fact", ",", "diagnosis", "of", ...
PMC11658074
h, i Immunofluorescence staining of γ-H2AX in the cell nucleus in the five groups.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "h", ",", "i", "Immunofluorescence", "staining", "of", "γ-H2...
PMC10965680
The distance between the other breeds and Jining goats was relatively great, and at the same time, the distance was closer to that of Xiangdong goats, indicating that the degree of differentiation between Xiangdong goats and the other five breeds of goats was less than that between Xiangdong goats and Jining goats (Figure 3B).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8010066
Moreover, the Student's t-test and two-way ANOVA test confirmed the statistically significant association between the antibiogram pattern and the co-culture, the gene expression level in the wild type, and the recovered strains.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11637716
Early‐onset severe pulmonary arterial hypertension was treated with nitric oxide, sildenafil and bosentan.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Early‐onset", "severe", "pulmonary", "arterial", "hypertension", "was", ...
PMC6600253
It is now known that cancer is not a single disease, and the idea of a “monoshot” therapeutic strategy is misleading and outdated .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973
Methods: 800 pregnant women, previously diagnosed with IDA, in their first trimester from various rural villages around Andhra Pradesh, India were selected.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11604830
time = 2 min 42 s), the proper shim was performed (see Data S1), before the acquisition, on each PLN (left and right) and on each reference tube.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4395774
Transduced LSK cells (2 × 10) were left in culture, and 72 hours after transduction, GFP expression was analyzed by flow cytometry, and 1 week after transduction, cells were treated with benzonase and used to determine vector copy number.
[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10996034
no. 44671; SAB Biotherapeutics, Inc.) diluted at a ratio of 1:1,000.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "no.", "44671", ";", "SAB", "Biotherapeutics", ",", "Inc.", ")", ...
PMC11707832
The study revealed a substantial elevation in the median activity of α-mannosidase among patients with bacterial peritonitis, reaching a level 20 times higher than that observed in control subjects.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11721064
Cells matured in KSFM exhibited a polygonal epithelial morphology, characterized by small, cuboidal cells arranged in a regular, cobblestone-like pattern (Additional file 1: Fig. S2F).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10154097
miR-218-5p binding region was predicted by the bioinformatics tool starBase database (Figure 4(a)).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "miR-218", "-", "5p", "binding", "regio...
PMC9444294
An initial report characterized its application in immunohistochemistry, co-immunoprecipitation, and chromatin immunoprecipitation in several cell lines and in primary patient tumour tissue.14 In the current study, we confirm these uses, but also expand on the molecular biology applications for this antibody and the different types of samples where it can be used to detect SS18-SSX protein expression.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
The overall response rate (ORR) was 95.2%.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "overall", "response", "rate", "(", "ORR", ")", "was", "95.2", "%", "." ] } ]
PMC11802855
Membranes were blocked with QuickBlock Blocking Buffer for Western Blot from Biotechnology.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Membranes", "were", "blocked", "with", "QuickBlock", "Blocking", "Buffer", "for", ...
PMC10604092
Abnormal muscle and fat metabolism are widely accepted as crucial factors that affect the pathogenesis of cancer cachexia.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Abnormal", "muscle", "and", "fat", "me...
PMC11085211
GIST-T1 was purchased from CosmoBio (Tokyo, Japan), while GIST-48 and GIST-882 cells were kindly provided by Fletcher JA, MD (Harvard Medical School).
[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC9429973
Unfortunately, only a small proportion of patients participates in clinical studies.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Unfortunately", ",", "only", "a", "small", "proportion", "of", "patients", "part...
PMC9429973
This second interim analysis was performed in patients treated with monotherapy until progression, 43 months after the first inclusion.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "second", "interim", ...
PMC9784246
All data have been reported as the mean ± SE of triplicate results.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "data", "have", "been", "reported", "as", "the", "mean", "±", ...
PMC9429973
Patients on treatment were also followed up at 12 months to detect levels of CD26+ LSCs and correlated with BCR -ABL1 levels by qPCR.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9014716
The results showed the ability of inhibiting cell proliferation of OXA was recovered after the treatment of PS-T. (E and F) Clone numbers of human Bel-7404 and HepG2 cells were counting by Image J software. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11637820
Cold atmospheric plasma (CAP) is a form of ionized gas recognized as the fourth state of matter.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cold", "atmospheric", "plasma", "...
PMC11794588
Lupeol is a triterpene known for its anticancer, anti-inflammatory, and antioxidant effects.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lupeol", "is", "a", "triterpene", "known", "for", "its", "antica...
PMC9429973
localised amyloid deposition is commonly associated with ENMZL MALT-type, both localised and systemic amyloidosis may be found out in LPL.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "localised", "amyloid", ...
PMC6461034
Indeed, organoid treatment with the ABL inhibitor imatinib yielded negligible inhibition (IC50 imatinib = 4 or 6 μM for CRC0177 and CRC0254, respectively; Fig 7D) while the positive control (CML cell line K562) worked (Appendix Fig S11E), underscoring the value of INKA ranking for drug response prediction.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "...
PMC7987994
There is a vast number of cultivation media which differ in the constitution and concentration of the components.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "is", "a", "vast", "number", ...
PMC11769516
By day 12, most of the described indices had returned to normal levels .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "By", "day", "12", ",", "most", "of", "the", "described", "...
PMC11155445
From XRD analysis it was confirmed that acyl thiourea acted as a bidentate ligand and coordinated with metal through S and N atoms, the geometry of the complex had central metal atom Pd(ii), acyl thiourea, chlorido and triphenyl phosphine ligand (Fig. 20).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11637276
CDM, cell-derived matrix; MAPK, mitogen-activated protein kinase.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CDM", ",", "cell-derived", "matrix", ";", "MAPK", ",", "mitogen-activated", "protein", "kinase",...
PMC11612794
GFP-Dsn1, GFP-Dsn1 (S97A, S101A, S102A, and S111A), GFP-Dsn1, and Dsn1-spot were cloned into the plasmid containing approximately 2 kb homology arm around the start codon of Dsn1 with the puromycin resistance gene cassette and EcoGPT gene cassette by In-Fusion® HD (TAKARA) (pBS_Dsn1-N KI_GFP-Dsn1, _GFP-Dsn1, _GFP-Dsn1, or _Dsn1-spot_PuroR or _EcoGPT).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11753435
These approaches, such as bioPROTACs, AdPROMs, and ubiquibodies (uAbs), have relied on the existence of “off-the-shelf” binders, thus precluding degrader design to novel target substrates (4–10).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...