Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
Community
1
PMCID
string
Sentences
string
ner
list
PMC11240571
In addition, the anti-human PD-L1 antibody did not react with PD-L1 from mouse osteosarcoma cell line LM8 (Supplemental Figure S3B), suggesting that circulating exosomal PD-L1 was released from transplanted tumor cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "B-CellLine", "O", "O", "O", "O", "O", "O", ...
PMC9250505
Treatment concentration of NPB, 5 μM; Olaparib, 10 μM; Rucaparib, 5 μM; and Talazoparib, 5 μM. Columns are mean of triplicate experiments; bars, ±SD. *
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11700340
Topotecan and paclitaxel, combined with cisplatin, have yielded the best response rates; only combining cisplatin and topotecan has enhanced overall survival [3-5].
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11001582
After three washes in PBS-T, signals were visualized by chemiluminescence (Amersham imager 680) and quantifications performed using ImageJ software.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "thr...
PMC9872547
3-(4, 5- dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide colorimetric assay is a method that determines differences between viable cells and necrotic ones (22).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11474209
AuNPsTap water sample0.002 ng/mLGold and magnetic nanoparticles were conjugated to the MC-LR aptamer and corresponding complementary DNA fragments.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "AuNPsTap", "water", "sample0.002", "ng/mLGol...
PMC11765988
Previous studies have highlighted the critical role of CT in diagnosing both sarcoidosis and Hodgkin’s lymphoma by assessing mediastinal lymph node enlargement.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Previou...
PMC11762280
Compared with WT mice, the protein levels of N-GSDMD, cleaved PARP, cleaved caspase-3, and p-MLKL decreased in Zbp1 mice after UVB irradiation (Fig. 6H).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11661040
D-E) Western blot was used to analyze the expression of CGREF1, β-catenin and Cyclin D in tumor tissues of the two groups.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11805741
After completion of the treatment protocols listed below, cells were harvested using 0.05% trypsin (Gibco, USA) and 0.02% EDTA.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11774747
First, the delay between viral infection and VST infusion.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "First", ",", "the", "delay", "between", "viral", "infection", "and", "VST", "infusion", "....
PMC11587606
These experiments were repeated two times under identical conditions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "experiments", "were", "repeated", "two", "times", "under", "identical", "conditions", "." ] ...
PMC9429973
Treatment duration and BCR::ABL1 transcript type also remained independent predictors, but TKI generation and DMR duration did not.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Treatment", "duration", "and", "B...
PMC9429973
Of 78 patients, 24 patients were marker negative and 54 patients were marker positive before DLI (of the marker positive patients 23 were in CR/CRi/MLFS).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10969097
Most studies in this field tend to focus on evaluating isolated compounds extracted from mushrooms, rather than examining the overall extract itself.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Most", ...
PMC11063646
The skin irritation studies were conducted on Swiss albino mice (Lulekal et al., 2019) under Institutional Animal Ethics Committee (IAEC) approval number NGSMIPS/IAEC/AUG-2023/388.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8382973
In our study, the 2P23 gel dosage formulation was prepared using the gel method, and HEC was selected as the gelling agent.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11271800
In the early tumor stage, M1 TAMs initiate an inflammatory response together with other immune cells, while in the advanced tumor stage, M1 TAMs are transformed into M2 TAMs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10196713
Deferoxamine suppressed cisplatin-induced cell death in OVK18 and A2780 cells (Figs. 3A and S1A), indicating that cisplatin induces iron-dependent cell death; namely, ferroptosis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11420784
The result showed that PldA inhibits activation of the autophagy pathway in host cells both in vitro and in vivo.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "result", "showed", ...
PMC11792740
T cells, also referred to as T lymphocytes, are vital components of the adaptive immune system, primarily responsible for identifying and eliminating infected and tumor cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7192625
In these cases, not preserving distance would produce a distortion of the genomic correlation and would lead to randomized ChAs values distributed around 0 for all features.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11033180
Subsequently, we explored miniature postsynaptic currents (mPSCs) to assess synaptic spontaneous activity (minis recordings).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Subsequently", ",", "we", "explor...
PMC11680578
The cells were grown in DMEM-F12 (Dulbecco’s Modified Eagle Medium/Nutrient Mixture F-12, Hyclone) medium supplemented with 10% FBS (Fetal bovine serum, Hyclone) and penicillin, streptomycin, amphotericin B antibiotics at 37 °C with 5% CO2.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11794568
The expression and function of cytosolic-encoded mitochondrial transcription factor A (TFAM), one of the key regulators of mitochondrial biogenesis, has received extensive attention in a wide range of tumors.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11040965
Thus, here we tested whether restoration of high levels of proteasome subunits (by the exogenous addition of miR29b) re-establishes plasma cell killing by CD8 T cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11402217
As depicted in Figures 2G and S1, this stimulation escalates the intracellular calcium ion concentration in 143B and MG63 cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O" ], "tokens": [ "...
PMC11240448
When we randomly sampled analytes, constructed the STV, and calculated the DPD scores, certain cells were classified incorrectly (Supplementary Figure S8B).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11224020
b, Gating strategy to quantify DCs in skin draining lymph nodes (dLNs).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "b", ",", "Gating", "strategy", "to", "quantify", "DCs", ...
PMC11767725
Psoriasis is a chronic immune-mediated skin condition characterized by erythematous, scaly plaques resulting from excessive keratinocyte proliferation and incomplete differentiation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Psoriasis", "is", ...
PMC11679033
Typical features of lymphocyte nuclei observed using an epifluorescence microscope on microgels prepared for the alkaline comet assay are shown in Figure 5.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Typical...
PMC11760643
Cells were washed twice using an extracellular Ca solution (ECS; 145 mM NaCl, 2 mM CaCl2, 1 mM MgCl2, 5 mM KCl, 13 mM glucose, and 10 mM HEPES, pH 7.4), then preincubated with Fura‐2 AM loading buffer [2.5‐µM Fura‐2 AM (Thermo Fisher Scientific)/0.2% pluronic acid (Sigma Aldrich, St Louis, USA) in ECS] in the dark for 30 min at 37°C and 95% air/5% CO2.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11194678
The density of each band was normalized by β-actin. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "density", "of", "each", "band", "was", "normalized", "by", "β-actin", ".", "(" ...
PMC10698968
CPD were calculated at each passage as log2(N1/N0), where N0 is the number of cells seeded and N1 is the number of cells harvested at the end of the passage.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11301242
4Epigenetic characteristics of ecDNA amplification.(A) H3K27ac/H3K4me3 ChIP-seq tracks within the WGS-identified ecDNA region (chr8:125,212,305-129,685,893) in circular (HL60) and non-circular (MV411, MOLM13) AML samples (left), and the expression levels of oncogenes on this ecDNA (right). (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", ...
PMC11788920
Next, the precise amount of dCas9 (Sigma-Aldrich) protein stock was added to the RNP complexes, resulting in a final concentration of 12.5 nM per well and mixed gently by pipetting.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11706297
Each of them consists of an extracellular ligand-binding domain, a single hydrophobic transmembrane region, and an intracellular TK domain.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "of", "the...
PMC9325715
Additionally, the mechanisms which are involved in the formation of the respective complexes were investigated.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "the", "mechanisms", "which", "are...
PMC9250505
Compared to NPB or Olaparib alone, the cells treated with a combination of NPB and Olaparib exhibited further decreased levels of pBADS99/BAD.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Compare...
PMC11359735
In the many proteomic analyses of Plasmodium sporozoites that have been published, CSP is among the most abundant proteins and virtually all of the C-terminal region has been detected by tryptic peptides and semi-tryptic fragments.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11754291
The keratinocytes were irradiated on days 3, 5, and 7 using an LED module with light parameters set to 10 mW/cm and 15 J/cm.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11703992
Currently, the temporal artery biopsy is considered as the “gold standard” .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Currently", ",", "the", "temporal", "artery", "biopsy", "is", "c...
PMC11727907
Furthermore, due to its transition from tetrameric to dimeric form, increased translocation of PKM2 into the nucleus was observed following IGF-1 treatment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11411131
Structures of the Luc-Sec (or Cys)-odc constructs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Structures", "of", "the", "Luc-Sec", "(", "or", "Cys)-odc", "constructs", "." ] } ]
PMC11224206
A startling observation was reported in 2018 in PLoS Biol by Chrétien et al. with the title ‘Mitochondria are physiologically maintained at close to 50 °C’, a temperature at which proteins would denature!
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11588085
EB Stemness and Mesoderm index in OVCAR3-KRAB.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "EB", "Stemness", "and", "Mesoderm", "index", "in", "OVCAR3-KRAB", "." ] } ]
PMC9424261
The interaction between GSS and MDM2 in tissues detected by co-IP experiments (Fig. 6G), which was consistent with the experimental results in vitro.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6222635
The concentration and quality of the extracted RNA was tested using a nucleic acid analyzer.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "concentration", "and", "quality", "of", "the", "extr...
PMC11543885
Fixed Modification: Set Carbamidomethyl (C) as the fixed modification.ii.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fixed", "Modification", ":", "Set", "Carbamidomethyl", "(", "C", ")", "as", ...
PMC11049294
A decrease in Fl-Gb3 could be observable after 6 h of incubation (2495 ± 494 MFI), a significant trend that could be detected in the 24 h observation period.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11742231
Specifically, we trained and evaluated each model five times using different random seeds to account for variability due to initialization and data shuffling and applied paired two-tailed t-tests to compare the performance of MGATAF against each baseline method on both the GDSC and CCLE datasets for the Pearson Correlation Coefficient (PCC) and Root Mean Square Error (RMSE) metrics.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9436459
The trans–trans and cis–trans types of classic MDAAs could be easily determined by analysis of the coupling constant of H-4" with H-3" and H-5" (generally, large J3"/4" and J4"/5" for trans–trans; small J3"/4" and large J4"/5" for cis–trans:) in the H NMR spectrum with resolvable signals.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10907726
Therefore, 100 μM of DATS was used as working condition in the following experiments.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "100", "μM", "of", "DATS", "was", "u...
PMC9429973
A. Casamayor Garcia, M. V. Aznar Moreno, J. Coll Vallier, M. E. Sola Aparicio, E. Gomez Arteta, M. J. Paloma Mora, M. Rodriguez Calvillo, I. Insausti Gorbea, M. I. Moreno Izco, M. Lopez San Martín, R. Monreal Beortegui, J. Anniccherico Sánchez, I. Mugica Muñagorri, D. G. Gabaldon Limas, J. Illarramendi Esteban, R. J. Breeze, C. Ceballos Bolaños, A. M. Redondo Izal HEMATOLOGY; CARDIOVASCULAR RADIOLOGY; INTERNAL MEDICINE; VASCULAR SURGERY, HOSPITAL UNIVERSITARIO DE NAVARRA, PAMPLONA, Spain Background: Guidelines suggest anticoagulation therapy alone over thrombolytic therapy in addition to anticoagulation in the treatment of deep vein thrombosis (DVT).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9351137
As expected, for each chromatin remodeling subunit (CRS) tested, the antibody staining decorated the interphase nuclei (Additional file 1: Fig. S1).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
5/7 (71%) tested pts having activating mutations in the JAK-STAT pathway.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "5/7", "(", "71", "%", ")", "tested", "pts", "having", "act...
PMC11655498
ZEBs silence the promoter of BZLF1 (Zp) in a cell-dependent manner, thus promoting the maintenance of viral latency.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ZEBs", "silence", ...
PMC6160470
Both Annexin V positive and Annexin V/7-AAD double positive cells were determined and the percentage of total apoptotic cells was calculated.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Both", "Annexin", ...
PMC11283030
d. ACLY knockdown induced apoptosis of 786-O and A498 cells (FCM).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ "d.", "ACLY", "knockdown", "induced", "apoptosis", "of", "786-O"...
PMC11628904
Two‐way ANOVA with Sidak's multiple comparison test was used when appropriate depending upon the number of independent variables in each experiment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Two‐way", "A...
PMC9250505
Consistently exposure of control transfected PDO1 to NPB decreased cell viability and increased CASPASE 3/7 activity compared to vehicle-exposed PDO1.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consistently", "exposure", "...
PMC11591030
The yields of purified polysaccharides were 29.32% of the total AOP, with a total sugar content of 88.79%.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "yields", "...
PMC11089031
In this study, we found that ZNF692 was upregulated in ccRCC and that its expression was increased in a stage-specific manner.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this",...
PMC11721295
Although the number of fibroblasts in the human samples was limited, we corroborated some in vitro data, including increased expression of CXCL1 in the KRAS-driven versus non–KRAS-driven lung cancer samples (Supplemental Figure 7A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11718809
The MAPK signaling pathway is involved in the regulation of many important physiological processes, including milk synthesis .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "MAPK", "signaling", "pathway", ...
PMC11474209
Here, we present a thorough assessment of the evidence supporting MC-LR as a mitotoxicant, explain MC detection techniques, and propose a novel theory for the relevance of MC-induced breakdown of mitochondrial machinery and its myriad biological repercussions in health and disease.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8956657
MERS Middle East respiratory syndrome-related coronavirus, WT wild-type, DAPI 4′,6-diamidino-2-phenylindole, Fn/c fluorescence intensity in the nucleus divided by fluorescence intensity in the cytoplasm.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11734514
Sipholenol A, isolated from C. siphonella, has also been reported as an inhibitor of protein tyrosine kinase 6 (PTK6) identified for its role in promoting growth factor signaling and migration in MDA-MB-231 breast cancer cells.17,18 Despite previous reviews suggesting limited inflammation inhibition of marine compounds, this research showed that A549 cells ability for inflammation inhibition and wound healing assay weakened during treatment with C. aerizusa extract.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
.
[ { "tags": [ "O" ], "tokens": [ "." ] } ]
PMC11715478
However, no significant differential changes were found between the groups for CD19 pan B (P=0.24), CD4 helper T (P=0.29), and CD8 cytotoxic T (P=0.56) cell populations.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11144200
The advantages of liposomes as drug delivery vector lie in their good biocompatibility, biodegradability, and low toxicity.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "advantages", "of", "liposo...
PMC11746942
It was reported that cAMP/PKA and increased phosphorylation of Src at serine were found 40 years ago , after which a consensus PKA site at serine 17 of Src (S17) was found .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8992508
A library of 16 of non-natural homoverrucosanoid-(cyclohepta[e]hydrindanoids) derived esters [Figure 21] were examined as inhibitors of the membrane transporter proteins ABCB1, ABCG2 and ABCC1, using the calcein AM accumulation assay on both ABCB1 overexpressing A2780 adr cells and ABCC1 overexpressing H69AR cells, and the Hoechst 33342 accumulation assay using the ABCG2 overexpressing MDCK II ABCG2 cell line respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9352806
As shown in Fig. 3B, the protein level of daf-16/FoxO1 and LGG-1 was detected.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "shown", "in", "Fig.", "3B", ",", "the", "protei...
PMC8750422
As shown in Figure 4a, intracellular NO production was induced by LPA treatment and GPR87 overexpression in A549 lung adenocarcinoma cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "As", ...
PMC11139449
To enhance the confirmation process, an additional primer was utilized as a control, which produced a 400 bp band in PCR analysis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11129910
There were eight cases (61.53%) that exhibited pure spindle morphology of variable appearance, whereas five (38.46%) contained invasive ductal carcinoma comprising <20% of the tumor mass in addition to the spindle cell carcinoma.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11592008
In contrast, talabostat treatment of HaSKpw cells decreased NLRP1 protein expression (Figure 3C).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "contrast", ",", "talabostat", "treatment", ...
PMC11001582
Overall, these results reveal an age-dependent neurodegeneration in the spinal cord of our polyGR and polyPR knock-in mouse models.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overall", ",", "these", ...
PMC11718109
E Fluorescence image of a representative area of the MSN-seeded chamber where only axons of the tdTomato-TH-positive DA neurons (white) have innervated the MSN-containing chamber (unlabeled).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11699465
TMEM199 is involved in CD274 mRNA gene expression by the transcriptional regulation of the upstream transcription factors or cofactors of CD274, such as IFNGR1, IRF1, MTMR9, KAT8, and Trim28.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11758416
Note: Supernatant may be discarded or saved for use at later time to assess levels of granzyme B, Perforin, IFNγ, LDH etc.c.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC8540692
Contrarily, the highest tested concentration, e.g., 20 µM CCM, was cytotoxic to all the cell lines.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Contrarily", ",", "the", ...
PMC11704135
C NMR (CDCl3) δ(ppm) of compound 8: 192.12, 174.14, 167.51, 148.65, 141.82, 137.97, 131.78, 123.99 and 29.39.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11055510
RNA pull-down and Dual luciferase assay were used to explain the underlying mechanism by which circMAN1A2 regulates OC cell proliferation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RNA", "pull-down", "and", ...
PMC11283030
P < 0.05, **P < 0.01 vs. VC.Fig.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", "<", "0.05", ",", "*", "*", "P", "<", "0.01", "vs.", "VC.Fig", "." ...
PMC11727907
At the end of the experiments, a set of ARPE-19 cells were lysed in RIPA buffer supplemented with protease and phosphatase inhibitors.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11502443
Herein, we report the first differences in signaling between the two variants.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Herein", ",", "we", "report", "the", "first", "differences", "in", "s...
PMC11612508
Surgery is the most effective method, but total removal is nearly unattainable due to invasiveness.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Surgery", "is", "the", "most", "effective", "method", ...
PMC9454852
DHR 123 fluorescence was read with a plate-reader by using a 485 nm excitation filter and a 530 nm emission filter.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "DHR", "123", "flu...
PMC9429973
Moreover, MM MSC have prominent cancer-associated phenotype and increased transcription of some tandemly repeated sequences.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "MM", "MSC", "have", "prominent", ...
PMC9428827
The molecule was tested for low endotoxin levels, and the biological activity was evaluated using the CTLL-2 cell proliferation assay.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "molecule", ...
PMC11670407
In the present study, we found that OTULIN can act as a key molecule in promoting cisplatin resistance; this cisplatin-dependent upregulation of OTULIN expression markedly decreased the sensitivity of osteosarcoma cells to cisplatin-induced cell death.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11342785
The weaker (EC50∼ 5.92 μM) FUS-CORE synMAP produced more disperse and less tightly-packed MT bundles (40) (Fig. 2D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC7757104
It was also observed that certain OPNc-dependent protumorigenic functions were mediated by the PI3K/AKT signaling pathway, demonstrating the role of OPNc in ovarian cancer tumor progression through the activation of these signaling pathways (30).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11204465
Four oxisterigmatocystins analogues of oxisterigmatocystins E-H (16–19) were isolated from secondary metabolites of the fungus Botryotrichum piluliferum .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Four", "oxisterigmatocystins", "analogu...
PMC9429973
Methods: Archival BM trephines were sourced from patients with PGF (n=20), AA at Diagnosis (AA_DX) (n=15), AA at Progression (AA_PROG) to MDS/AML (n=15) and normal controls (NC) (n=20).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11285179
CEBPB and Sp1 can potentially regulate CCL28, while only CEBPB was highly expressed in hypoxic tumor cells (as listed in Supplementary Table 1).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973
Tinostamustine-pretreated myeloma cells showed a higher level of daratumumab binding, as demonstrated by anti-human-IgG1-AF488 staining.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tinostamustine-pretreated", "myeloma", "cells", "showed", "a...
PMC11697065
Commercial vectors are often engineered to drive constitutively high levels of recombinant protein transcription that consequently leads to a high protein folding burden and a strong selection pressure toward host cell adaptation , , .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...