OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC11001582	Source data a, Representative image of the cortex (area delineated in yellow), enhanced magnification of the motor cortex (area delineated in green), and quantification of NeuN-positive (red) cell density in the whole cortex and in motor cortex in WT, (GR)400 and (PR)400 mice at 12 months of age.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11786704	It is supported that PC capsules offer a new therapeutic option as a potentially effective strategy for the treatment of diabetic chronic wounds.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", ...
PMC9352806	We next used daf-16 deficient-mutant to verify the fat-lowering property of BMS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "next", "used", "daf-16", "deficient-mutant", "to", "verify", "the", "fat-l...
PMC10605143	Therefore, we assume that HSF1-dependent inhibition may occur at the chromatin level, especially since it was demonstrated that HSF1 can participate in chromatin organization .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC7153288	The stem sample was then ground in a mortar with sterile 0.9% NaCl and the plant extract was spread on the Soya Flour Mannitol (SFM) agar plate containing 30 μg/ml nalidixic acid, 50 μg/ml cycloheximide, and 50 μg/ml nystatin to suppress the growth of Gram-negative bacteria and fungi.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9727330	Colon cancer is one of the most commonly diagnosed cancers and a leading cause of cancer death worldwide.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Colon", "cancer", "is", "one", "of", ...
PMC11772585	Recently, the disruption of mitochondrial homeostasis, such as through efforts to reduce mitochondrial MMP and mass, has emerged as a potential therapeutic approach for cancer treatment [41–43].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11277157	We performed RNA-seq global analysis to assess the role of knockdown using siRNA for DJ-1 levels.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "performed", "RNA-seq", "global", "analysis", "to...
PMC8170755	The protein bands were then transferred to nitrocellulose membranes (Millipore) using a semi-dry transfer membrane system (Cleaver Scientific Ltd, Warwickshire, United Kingdom).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10932641	lncRNA can also serve as prognostic biomarkers for RCC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "lncRNA", "can", "also", "serve", "as", "prognostic", "biomarkers", "for", "RCC", "." ] } ]
PMC9503669	Src-family kinase activity, in cooperation with ZAP-70/Syk kinases, ultimately triggers activation of PI3K, enhancing membrane levels of PIP3 and activation of Arf1 and Arf6.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10975211	Antimicrobial peptides (AMPs) exhibit diverse structural characteristics, including α-helical, β-sheet, extended, and loop peptides.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Antimicrobial", "peptides", ...
PMC9429973	Image: Summary/Conclusion: In sum, our comprehensive analyses revealed fundamentally different mechanisms driving either type-1 or type-2 T-ALL relapse and indicate that differential capacities of disease evolution are already inherent to the molecular setup of the initial leukemia.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Eligible patients were those treated with RUX and then FEDR, who had spleen palpation at FEDR initiation, and who had completed ≥1 cycle of FEDR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10823017	In both cases, the data represent N=3 independent experiments, mean ± SEM. (**	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "both", "cases", ",", "the", "data", ...
PMC9429973	In October 2021, recruitment of the targeted 36 pts was completed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "October", "2021", ",", "recruitment", "of", "the", "targeted", "36", ...
PMC11699465	For instance, when TMEM199 was knocked down, a significant decrease in the CD274 mRNA expression level was observed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "instance", ",", ...
PMC11476222	Key challenges in the field include the need for less expensive and more efficient methods for recovering gangliosides from complex biological samples and the need for improved accuracy and precision in analyzing specific ganglioside entities.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9841531	For compounds with an inhibitory power over 50% against a single target or 20% (+SEM) against all three ABC transporters, full-blown concentration-effect curves between 100 nM and 100 μM final compound concentrations have been generated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11569208	To confirm that our novel bioengineered virus has increased infectivity across multiple tumor contexts, we tested both VSV∆51-NTC and VSV∆51-shACP2 in several cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11766350	rAAV is one of the most popular vectors to achieve this due to its versatile range of target cells and low immunogenicity .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "rAAV", "is",...
PMC11802855	The results showed that BMDMs co-cultured with CXCL7-OE cells generated a significantly higher number of multinucleated osteoclasts compared to the NC group, indicating that elevated CXCL7 expression enhances osteoclastogenesis (Fig. 7K).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11656657	Additionally, it has been reported that MDSC were highly enriched in mononuclear cell populations isolated from peripheral blood of G-CSF-mobilized haploidentical donors and they display a marked inhibitory effect in NBL patients treated with CAR.GD2 T-cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3765139	Expression of CD133 and CD117 in melanoma cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Expression", "of", "CD133", "and", "CD117", "in", "melanoma", "cell", "lines", "." ] } ]
PMC11599565	Interestingly, these changes do not occur in the histologically related primary invasive and metastatic melanoma.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interestingly", ",", "these", "changes", "do", "not", ...
PMC9429973	Risk factors for SPM in patients were older age and COPD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Risk", "factors", "for", "SPM", "in", "patients", "were", "older", "age", "and", ...
PMC11026382	This process is documented in Jupyter notebook 4_ModelAndDMSData.ipynb in the associated github repository.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "process", "is", "documented", "in", "Jupyter", "notebook", "4_Model...
PMC11806106	Increasing concentrations of dynorphine A were applied followed by a saturating concentration of dynorphine A and the antagonist naloxone.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Increasing", "concentrations", "of", ...
PMC11653533	Moreover, ethanol extract of F. carica has shown an antipyretic effect, where a dose of 100 mg/kg body weight of the extract conveyed a noteworthy reduction in yeast-provoked elevated body temperature of rats within four hours (Patil et al., 2010).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5173112	Data represent the mean (± s.d.)	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "represent", "the", "mean", "(", "±", "s.d", ".", ")" ] } ]
PMC11770199	In this study, we integrated a fusogenic protein, FAST p14 of reptilian reovirus, into colon cancer and melanoma cells, demonstrating its ability to induce cell fusion and syncytia formation with both itself and adjacent p14-negative cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11394730	Resveratrol is a highly effective scavenger of radicals produced by cells and triggered by metals, enzymes, hydroxyls, and superoxides.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Resveratrol", ...
PMC9046263	Briefly, PCR products for both primer sets for ERVK3-1 were amplified using Q5 High-Fidelity DNA polymerase (New England BioLabs, M0491S).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11621493	This positional preference was also observed in PMAT and PDAT reactions, but not in MMAT assays.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "positional", "preference", "was", "also",...
PMC9351137	In telophase, all the tested CRS were found at the midbody.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "telophase", ",", "all", "the", "tested", "CRS", "were", "found", "at...
PMC9622879	Hence, the daily energy cost of the community in the no-CEMS scenario is the highest among the three scenarios.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hence", ",", "the", "d...
PMC11240052	Despite continuous advancements in surgery and chemotherapy, the 5-year overall global survival rate of ovarian cancer is approximately 40% (6).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11765243	For Treg differentiation, cells were cultured 48 h in anti-CD3-coated wells in the presence of anti-CD28 antibody (1 µg/mL), anti-IL-4 (5 µg/mL), anti-IFN-γ (10 µg/mL), 20 ng/mL human IL-2, and 5 ng/mL TGF-β1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11751675	Parthenolide has garnered considerable attention due to its diverse biological activities, which include anti-inflammatory, antitumor, antibacterial, antifungal, and notably, antiviral properties.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7642379	Heatmap of gene set analysis using GO biological processes and Piano consensus scores showed a different expression pattern between suspension cells (293-H and 293-F) and adherent cells (293E and 293T).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "...
PMC8992508	Fold resistance was calculated as ratio between the IC50 values of the substrate (MX) in presence or absence of inhibitor by the IC50 of parental cells without inhibitors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6742971	However, such a model where low avidity T cells have immune regulatory roles would require that these cells are controlled by mechanisms that are distinct to the ones that control high avidity T cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2193049	The radioactive band corresponding to the reference GFPha–Ub could be detected in all lanes where cells had been transfected with UPR-based plasmids (Fig. 2, lanes a–d) but not in mock-transfected cells (lane e).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	78% (7/9) patients were refractory to their last treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "78", "%", "(", "7/9", ")", "patients", "were", "refractory", "to", "their"...
PMC7823217	Patient-derived 3D bioprinted cancer models could be successfully used for in vitro drug screening of anti-cancer drugs in order to develop personalized treatments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patient...
PMC8633974	All cells listed were propagated in vented cap 75 cm U-shaped flasks at 37°C and 5% CO2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "cells", "listed", ...
PMC11021472	Although the higher overall levels of the linear transcripts potentially make them more efficient miR-150 sponges, the subcellular localization experiments do not support this function.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973	Palpable spleen size was assessed at the time of diagnosis or referral and stratified in three categories: non-palpable, <10 cm and ≥10 cm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11740508	S7048, SelleckChem®) given by oral gavage ± 0.2 mg/kg decitabine (Cat. #	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "S7048", ",", "SelleckChem", "®", ")", "given", "...
PMC10093184	After two hours of incubation at 37 °C, excessive liquid was carefully removed from the insert and 1 × 10 cells/0.5 mL/insert was seeded in a growth medium with the FCS concentration reduced to 1%.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10213179	For the binding assay performed to calculate the de-dissociation constant (KD), resuspended cells (A673) were washed with BB (DPBS+/+ containing 100 μg/mL yeast tRNA and 100 μg/mL BSA) and counted.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11366496	In different situations, it may be necessary to combine one or more of the above methods.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "different", "situations", ",", "it", ...
PMC11306331	Dissolution efficacy from blue optogenetic MBP-dimerization was compared to chemogenetic MBP-dimerization.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Dissolution", "efficacy", "from", "blue", "optogenetic", "MBP-dimerization", "was", "compared", ...
PMC11541409	A. Current approved adjuvant therapies for GIST.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A.", "Current", "approved", "adjuvant", "therapies", "for", "GIST", "." ] } ]
PMC11066331	We used the peak intensities as the input variables for the ML algorithms.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "used", "the", "peak", "intensities", "as", "the", "input", "var...
PMC9672323	The proliferative rate of PBMCs was measured by MTT (Sigma Aldrich, St Louis, USA) assay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "proliferative", "rate", "o...
PMC11684297	For scanning electron microscopy, the samples were prepared as follows: 190 µl of IA with 10 µl of PBS (untreated control) and 190 µl of IA with 10 µl of ZnO-NF (50 µg/ml) (sample) were incubated at 37° C for 24 h for amyloid degradation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11790971	During image preprocessing, the 2PF and 3PF channels were normalized using pixel-wise division with the FAD and NADH solution images collected after imaging each replicate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11594588	A decrease in CoA concentration leads to cardiomyocyte hypertrophy .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "decrease", "in", "CoA", "concentration", "leads", "to", "cardiomyocyte", "hypertrophy", "." ] } ...
PMC9429973	Among adults aged <60 years, HCT was reported for 29/60 (48%) patients, including 29/50 (58%) with ≥3 months of follow-up.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11474209	Similarly, levels of MC-LR from natural blooms of Microcystis in Japan between 1989 and 1991 ranged from 27 to 622 µg/g dry weight of biomass.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9599726	We next investigated the link between TFRC and YAP expressions or activity in human GIST samples.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "next", "investigated", "the", "link", "between",...
PMC10547921	To simplify its structure, Wayne C. Widdison's SAR study showed that fluorine substitution at the C11 position usually increases cytotoxicity several times, and the C20 center must be in S configuration for the molecule to remain active.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4277423	In this study, we used lentiviral vectors to deliver Cas9 and sgRNAs into HIV-1 susceptible human CD4 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "In", "this", "study", ",...
PMC10820104	10 m; Knauer, Germany) utilizing MeOH and H2O as eluting solvents, employing a flow rate of 5 mL/min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "10", "m", ...
PMC11467800	The intercellular dynamics among cancer cell subpopulations are of paramount importance in cancer, contributing to tumour heterogeneity, driving tumour progression, facilitating metastasis, inducing therapy resistance and giving rise to dormant clones.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11271278	All the cell lines were tested negative for mycoplasma.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "the", "cell", "lines", "were", "tested", "negative", "for", "mycoplasma", "." ] } ]
PMC4485648	On the other hand, Chen et al (22) used SFN at 5 μM concentration in normoxia and obtained only minor effect on cell survival.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3888431	For a reference-based approach the Illumina reads were mapped to the CHO-K1 draft genome published by Xu and coworkers with TopHat (version 1.4.1, default parameters) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11317131	In place of gIII, the SP contains the coding sequence for the integrase to be evolved.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "place", "of", "gIII", ",", "the", ...
PMC11593713	We observed statistically significant differences in TOS, TAC, OSI values, and GPx and GR activities depending on the type of viral infection (Figure 1, Table S1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11757131	Therefore, further exploration of how 3-HIB affects the function of PMECs through autophagy is a worthwhile direction for future research.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", ...
PMC11703992	Complications, high probability of recurrence, and delays in medical attention further complicate treatment and worsen survival outcomes .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Complications", ",", "high", "pro...
PMC7987994	After one day of incubation with the extracts, cell metabolic activity was evaluated using resazurin assay (Fig. 1, day 3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	However, the data should be analysed along with the data of other SNPs in the study to determine poor outcome of imatinib treatment in CML patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Skin lesion biopsy was not diagnostic, for two consecutive times, suggesting the possibility of erythema nodosum or vasculitis, with normal immunophenotyping.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	Image: Summary/Conclusion: Point-of-Care anti-CD19 CAR T-cell therapy, performed following a very short production time, induced high CR rate with an acceptable safety profile in a cohort of patients with high-risk R/R FL.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Image: Summary/Conclusion: Our data demonstrate that the CDK7 inhibitor THZ1 induces the apoptosis of AML cells and exerts synergistic antileukemia activity with azacytidine, which provide the rationale for combination treatment with AZA and THZ1 for AML.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Landmark survival in the FEDR and non-FEDR groups was 71.6% and 53.5% at 12 months, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Landmark", "survival", "in", "the...
PMC11568601	The mice were given water and food ad libitum.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mice", "were", "given", "water", "and", "food", "ad", "libitum", "." ] } ]
PMC11449273	It’s noteworthy to mention that plakoglobin expression alone did induced elevated PUMA level, and this effect was further increased in the p53-175 or p53-273 transfectants (S4 Fig).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8193813	Stack and CEMS types located at the Midland and St. Charles facilities are shown in Table 2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Stack", "and", "CEMS", "types", "located", ...
PMC11656380	A flow cytometry histogram plot illustrates the uptake of 70 kDa-dextran (red line) in comparison to the control (black line). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	The preliminary results confirm the feasibility and safety of TAG, allowing the administration also in elderly pts, with manageable safety.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "preli...
PMC10040136	The cells were rinsed 3 times with 10 mL of PBS after being seeded, and then 10 mL of control media or MSC-CM was added to the dish at the 24 h interval.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Of the 59 pts considered ineligible for CAR-T cell therapy, 46 (62%) presented ≥2 ineligibility criteria.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Of", "the", "59", "pts...
PMC10729469	Untreated non-transgenic mice served as controls.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Untreated", "non-transgenic", "mice", "served", "as", "controls", "." ] } ]
PMC11285179	Correlation analysis showed that RXRα expression positively correlates with ANGPT1 expression (Fig. 3H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Correlation", "analysis", "showed", "that", "RXRα", "expression",...
PMC7602170	Parts of combination treatment strategies are being investigated in early-stage clinical studies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Parts", "of", "combination", "treatment", "strategies", "are", "being", "investigated"...
PMC11632064	P < 0.05, P < 0.1, one-way ANOVA with Dunnett’s multiple comparison test.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", "<", "0.05", ",", "P", "<", "0.1", ","...
PMC11721277	Fractions of each phase (100 μL) were collected in a pre-weighed tube and their activity and weight were measured.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fractions", "of", ...
PMC10547921	Additionally, compound 5 establishes a hydrogen bond to the main chain carbonyl group of Gly100 via their C9–OH group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "compoun...
PMC11746948	The xenograft experiment follows the humane endpoint.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "xenograft", "experiment", "follows", "the", "humane", "endpoint", "." ] } ]
PMC11604015	Another article found that CD7-negative recurrences were contributed to CD7 transcriptional silencing rather than genetic mutations, although the exact source of these CD7-negative recurrences was also unclear .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6034753	Although we have observed co-localisation of Meq and apoptin in the nucleus of transfected fibroblasts and in MSB-1 cells (Figure 1), we don't know whether Meq and its nuclear localisation signals are directly involved in the active nuclear translocation of apoptin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The clinical course of FL is variable, and it has median overall survival of 10 to 12 years.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "clinical", "course", "of",...
PMC11682525	In line with this expectation, hHFSCs exhibited remarkable resilience even when exposed to hypoxic conditions for up to 3 days.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "line", "wit...
PMC9429973	The randomized, placebo-controlled, phase 3 QUAZAR AML-001 trial evaluated oral azacitidine (Oral-AZA; formerly CC-486), a hypomethylating agent, in patients with AML in first remission (CR1) after IC, who were not eligible for hematopoietic stem cell transplantation (HSCT).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10154881	Mice bearing E.G‐7/N4 were inoculated intratumorally with 10 TCID50 of rMV‐SLAMblind (rMV) or saline (MOCK), twice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mice", "bearing", ...
PMC10891340	CCCP acts as an uncoupling agent that increases the versatility of the inner mitochondrial membrane, thereby depolarizing mitochondria.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CCCP", "acts", "as", "an", ...

PMC11001582

Source data a, Representative image of the cortex (area delineated in yellow), enhanced magnification of the motor cortex (area delineated in green), and quantification of NeuN-positive (red) cell density in the whole cortex and in motor cortex in WT, (GR)400 and (PR)400 mice at 12 months of age.

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PMC11786704

It is supported that PC capsules offer a new therapeutic option as a potentially effective strategy for the treatment of diabetic chronic wounds.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", ...

PMC9352806

We next used daf-16 deficient-mutant to verify the fat-lowering property of BMS.

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PMC10605143

Therefore, we assume that HSF1-dependent inhibition may occur at the chromatin level, especially since it was demonstrated that HSF1 can participate in chromatin organization .

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PMC7153288

The stem sample was then ground in a mortar with sterile 0.9% NaCl and the plant extract was spread on the Soya Flour Mannitol (SFM) agar plate containing 30 μg/ml nalidixic acid, 50 μg/ml cycloheximide, and 50 μg/ml nystatin to suppress the growth of Gram-negative bacteria and fungi.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9727330

Colon cancer is one of the most commonly diagnosed cancers and a leading cause of cancer death worldwide.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Colon", "cancer", "is", "one", "of", ...

PMC11772585

Recently, the disruption of mitochondrial homeostasis, such as through efforts to reduce mitochondrial MMP and mass, has emerged as a potential therapeutic approach for cancer treatment [41–43].

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PMC11277157

We performed RNA-seq global analysis to assess the role of knockdown using siRNA for DJ-1 levels.

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PMC8170755

The protein bands were then transferred to nitrocellulose membranes (Millipore) using a semi-dry transfer membrane system (Cleaver Scientific Ltd, Warwickshire, United Kingdom).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10932641

lncRNA can also serve as prognostic biomarkers for RCC.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "lncRNA", "can", "also", "serve", "as", "prognostic", "biomarkers", "for", "RCC", "." ] } ]

PMC9503669

Src-family kinase activity, in cooperation with ZAP-70/Syk kinases, ultimately triggers activation of PI3K, enhancing membrane levels of PIP3 and activation of Arf1 and Arf6.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10975211

Antimicrobial peptides (AMPs) exhibit diverse structural characteristics, including α-helical, β-sheet, extended, and loop peptides.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Antimicrobial", "peptides", ...

PMC9429973

Image: Summary/Conclusion: In sum, our comprehensive analyses revealed fundamentally different mechanisms driving either type-1 or type-2 T-ALL relapse and indicate that differential capacities of disease evolution are already inherent to the molecular setup of the initial leukemia.

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PMC9429973

Eligible patients were those treated with RUX and then FEDR, who had spleen palpation at FEDR initiation, and who had completed ≥1 cycle of FEDR.

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PMC10823017

In both cases, the data represent N=3 independent experiments, mean ± SEM. (**

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PMC9429973

In October 2021, recruitment of the targeted 36 pts was completed.

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PMC11699465

For instance, when TMEM199 was knocked down, a significant decrease in the CD274 mRNA expression level was observed.

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PMC11476222

Key challenges in the field include the need for less expensive and more efficient methods for recovering gangliosides from complex biological samples and the need for improved accuracy and precision in analyzing specific ganglioside entities.

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PMC9841531

For compounds with an inhibitory power over 50% against a single target or 20% (+SEM) against all three ABC transporters, full-blown concentration-effect curves between 100 nM and 100 μM final compound concentrations have been generated.

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PMC11569208

To confirm that our novel bioengineered virus has increased infectivity across multiple tumor contexts, we tested both VSV∆51-NTC and VSV∆51-shACP2 in several cell lines.

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PMC11766350

rAAV is one of the most popular vectors to achieve this due to its versatile range of target cells and low immunogenicity .

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PMC11802855

The results showed that BMDMs co-cultured with CXCL7-OE cells generated a significantly higher number of multinucleated osteoclasts compared to the NC group, indicating that elevated CXCL7 expression enhances osteoclastogenesis (Fig. 7K).

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PMC11656657

Additionally, it has been reported that MDSC were highly enriched in mononuclear cell populations isolated from peripheral blood of G-CSF-mobilized haploidentical donors and they display a marked inhibitory effect in NBL patients treated with CAR.GD2 T-cells .

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PMC3765139

Expression of CD133 and CD117 in melanoma cell lines.

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PMC11599565

Interestingly, these changes do not occur in the histologically related primary invasive and metastatic melanoma.

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PMC9429973

Risk factors for SPM in patients were older age and COPD.

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PMC11026382

This process is documented in Jupyter notebook 4_ModelAndDMSData.ipynb in the associated github repository.

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PMC11806106

Increasing concentrations of dynorphine A were applied followed by a saturating concentration of dynorphine A and the antagonist naloxone.

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PMC11653533

Moreover, ethanol extract of F. carica has shown an antipyretic effect, where a dose of 100 mg/kg body weight of the extract conveyed a noteworthy reduction in yeast-provoked elevated body temperature of rats within four hours (Patil et al., 2010).

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PMC5173112

Data represent the mean (± s.d.)

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PMC11770199

In this study, we integrated a fusogenic protein, FAST p14 of reptilian reovirus, into colon cancer and melanoma cells, demonstrating its ability to induce cell fusion and syncytia formation with both itself and adjacent p14-negative cancer cells.

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PMC11394730

Resveratrol is a highly effective scavenger of radicals produced by cells and triggered by metals, enzymes, hydroxyls, and superoxides.

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PMC9046263

Briefly, PCR products for both primer sets for ERVK3-1 were amplified using Q5 High-Fidelity DNA polymerase (New England BioLabs, M0491S).

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PMC11621493

This positional preference was also observed in PMAT and PDAT reactions, but not in MMAT assays.

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PMC9351137

In telophase, all the tested CRS were found at the midbody.

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PMC9622879

Hence, the daily energy cost of the community in the no-CEMS scenario is the highest among the three scenarios.

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PMC11240052

Despite continuous advancements in surgery and chemotherapy, the 5-year overall global survival rate of ovarian cancer is approximately 40% (6).

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PMC11765243

For Treg differentiation, cells were cultured 48 h in anti-CD3-coated wells in the presence of anti-CD28 antibody (1 µg/mL), anti-IL-4 (5 µg/mL), anti-IFN-γ (10 µg/mL), 20 ng/mL human IL-2, and 5 ng/mL TGF-β1.

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PMC11751675

Parthenolide has garnered considerable attention due to its diverse biological activities, which include anti-inflammatory, antitumor, antibacterial, antifungal, and notably, antiviral properties.

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PMC7642379

Heatmap of gene set analysis using GO biological processes and Piano consensus scores showed a different expression pattern between suspension cells (293-H and 293-F) and adherent cells (293E and 293T).

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PMC8992508

Fold resistance was calculated as ratio between the IC50 values of the substrate (MX) in presence or absence of inhibitor by the IC50 of parental cells without inhibitors.

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PMC6742971

However, such a model where low avidity T cells have immune regulatory roles would require that these cells are controlled by mechanisms that are distinct to the ones that control high avidity T cells.

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PMC2193049

The radioactive band corresponding to the reference GFPha–Ub could be detected in all lanes where cells had been transfected with UPR-based plasmids (Fig. 2, lanes a–d) but not in mock-transfected cells (lane e).

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PMC9429973

78% (7/9) patients were refractory to their last treatment.

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PMC7823217

Patient-derived 3D bioprinted cancer models could be successfully used for in vitro drug screening of anti-cancer drugs in order to develop personalized treatments.

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PMC8633974

All cells listed were propagated in vented cap 75 cm U-shaped flasks at 37°C and 5% CO2.

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PMC11021472

Although the higher overall levels of the linear transcripts potentially make them more efficient miR-150 sponges, the subcellular localization experiments do not support this function.

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PMC9429973

Palpable spleen size was assessed at the time of diagnosis or referral and stratified in three categories: non-palpable, <10 cm and ≥10 cm.

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PMC11740508

S7048, SelleckChem®) given by oral gavage ± 0.2 mg/kg decitabine (Cat. #

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PMC10093184

After two hours of incubation at 37 °C, excessive liquid was carefully removed from the insert and 1 × 10 cells/0.5 mL/insert was seeded in a growth medium with the FCS concentration reduced to 1%.

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PMC10213179

For the binding assay performed to calculate the de-dissociation constant (KD), resuspended cells (A673) were washed with BB (DPBS+/+ containing 100 μg/mL yeast tRNA and 100 μg/mL BSA) and counted.

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PMC11366496

In different situations, it may be necessary to combine one or more of the above methods.

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PMC11306331

Dissolution efficacy from blue optogenetic MBP-dimerization was compared to chemogenetic MBP-dimerization.

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PMC11541409

A. Current approved adjuvant therapies for GIST.

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PMC11066331

We used the peak intensities as the input variables for the ML algorithms.

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PMC9672323

The proliferative rate of PBMCs was measured by MTT (Sigma Aldrich, St Louis, USA) assay.

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PMC11684297

For scanning electron microscopy, the samples were prepared as follows: 190 µl of IA with 10 µl of PBS (untreated control) and 190 µl of IA with 10 µl of ZnO-NF (50 µg/ml) (sample) were incubated at 37° C for 24 h for amyloid degradation.

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PMC11790971

During image preprocessing, the 2PF and 3PF channels were normalized using pixel-wise division with the FAD and NADH solution images collected after imaging each replicate.

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PMC11594588

A decrease in CoA concentration leads to cardiomyocyte hypertrophy .

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PMC9429973

Among adults aged <60 years, HCT was reported for 29/60 (48%) patients, including 29/50 (58%) with ≥3 months of follow-up.

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PMC11474209

Similarly, levels of MC-LR from natural blooms of Microcystis in Japan between 1989 and 1991 ranged from 27 to 622 µg/g dry weight of biomass.

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PMC9599726

We next investigated the link between TFRC and YAP expressions or activity in human GIST samples.

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PMC10547921

To simplify its structure, Wayne C. Widdison's SAR study showed that fluorine substitution at the C11 position usually increases cytotoxicity several times, and the C20 center must be in S configuration for the molecule to remain active.

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PMC4277423

In this study, we used lentiviral vectors to deliver Cas9 and sgRNAs into HIV-1 susceptible human CD4 cells.

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PMC10820104

10 m; Knauer, Germany) utilizing MeOH and H2O as eluting solvents, employing a flow rate of 5 mL/min.

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PMC11467800

The intercellular dynamics among cancer cell subpopulations are of paramount importance in cancer, contributing to tumour heterogeneity, driving tumour progression, facilitating metastasis, inducing therapy resistance and giving rise to dormant clones.

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PMC11271278

All the cell lines were tested negative for mycoplasma.

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PMC4485648

On the other hand, Chen et al (22) used SFN at 5 μM concentration in normoxia and obtained only minor effect on cell survival.

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PMC3888431

For a reference-based approach the Illumina reads were mapped to the CHO-K1 draft genome published by Xu and coworkers with TopHat (version 1.4.1, default parameters) .

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PMC11317131

In place of gIII, the SP contains the coding sequence for the integrase to be evolved.

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PMC11593713

We observed statistically significant differences in TOS, TAC, OSI values, and GPx and GR activities depending on the type of viral infection (Figure 1, Table S1).

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PMC11757131

Therefore, further exploration of how 3-HIB affects the function of PMECs through autophagy is a worthwhile direction for future research.

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PMC11703992

Complications, high probability of recurrence, and delays in medical attention further complicate treatment and worsen survival outcomes .

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PMC7987994

After one day of incubation with the extracts, cell metabolic activity was evaluated using resazurin assay (Fig. 1, day 3).

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PMC9429973

However, the data should be analysed along with the data of other SNPs in the study to determine poor outcome of imatinib treatment in CML patients.

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PMC9429973

Skin lesion biopsy was not diagnostic, for two consecutive times, suggesting the possibility of erythema nodosum or vasculitis, with normal immunophenotyping.

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PMC9429973

Image: Summary/Conclusion: Point-of-Care anti-CD19 CAR T-cell therapy, performed following a very short production time, induced high CR rate with an acceptable safety profile in a cohort of patients with high-risk R/R FL.

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PMC9429973

Image: Summary/Conclusion: Our data demonstrate that the CDK7 inhibitor THZ1 induces the apoptosis of AML cells and exerts synergistic antileukemia activity with azacytidine, which provide the rationale for combination treatment with AZA and THZ1 for AML.

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PMC9429973

Landmark survival in the FEDR and non-FEDR groups was 71.6% and 53.5% at 12 months, respectively.

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PMC11568601

The mice were given water and food ad libitum.

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PMC11449273

It’s noteworthy to mention that plakoglobin expression alone did induced elevated PUMA level, and this effect was further increased in the p53-175 or p53-273 transfectants (S4 Fig).

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PMC8193813

Stack and CEMS types located at the Midland and St. Charles facilities are shown in Table 2.

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PMC11656380

A flow cytometry histogram plot illustrates the uptake of 70 kDa-dextran (red line) in comparison to the control (black line). (

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PMC9429973

The preliminary results confirm the feasibility and safety of TAG, allowing the administration also in elderly pts, with manageable safety.

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PMC10040136

The cells were rinsed 3 times with 10 mL of PBS after being seeded, and then 10 mL of control media or MSC-CM was added to the dish at the 24 h interval.

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PMC9429973

Of the 59 pts considered ineligible for CAR-T cell therapy, 46 (62%) presented ≥2 ineligibility criteria.

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PMC10729469

Untreated non-transgenic mice served as controls.

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PMC11285179

Correlation analysis showed that RXRα expression positively correlates with ANGPT1 expression (Fig. 3H).

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PMC7602170

Parts of combination treatment strategies are being investigated in early-stage clinical studies.

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PMC11632064

P < 0.05, P < 0.1, one-way ANOVA with Dunnett’s multiple comparison test.

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PMC11721277

Fractions of each phase (100 μL) were collected in a pre-weighed tube and their activity and weight were measured.

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PMC10547921

Additionally, compound 5 establishes a hydrogen bond to the main chain carbonyl group of Gly100 via their C9–OH group.

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PMC11746948

The xenograft experiment follows the humane endpoint.

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PMC11604015

Another article found that CD7-negative recurrences were contributed to CD7 transcriptional silencing rather than genetic mutations, although the exact source of these CD7-negative recurrences was also unclear .

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PMC6034753

Although we have observed co-localisation of Meq and apoptin in the nucleus of transfected fibroblasts and in MSB-1 cells (Figure 1), we don't know whether Meq and its nuclear localisation signals are directly involved in the active nuclear translocation of apoptin.

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PMC9429973

The clinical course of FL is variable, and it has median overall survival of 10 to 12 years.

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PMC11682525

In line with this expectation, hHFSCs exhibited remarkable resilience even when exposed to hypoxic conditions for up to 3 days.

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PMC9429973

The randomized, placebo-controlled, phase 3 QUAZAR AML-001 trial evaluated oral azacitidine (Oral-AZA; formerly CC-486), a hypomethylating agent, in patients with AML in first remission (CR1) after IC, who were not eligible for hematopoietic stem cell transplantation (HSCT).

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PMC10154881

Mice bearing E.G‐7/N4 were inoculated intratumorally with 10 TCID50 of rMV‐SLAMblind (rMV) or saline (MOCK), twice.

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PMC10891340

CCCP acts as an uncoupling agent that increases the versatility of the inner mitochondrial membrane, thereby depolarizing mitochondria.

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