OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC10502403	In the stimulated state, IFN-γ production was more dependent on ATP synthesis, which was supported by the higher OXPHOS gene expression observed in αβ-TCR-transduced γδ-T cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10968586	Moreover, in hypoxic MCF-7 cells, 75–200 μM HT reduced the amount of PARP-1, a DNA-binding protein involved in oxidative stress response, but inhibition of PARP-1 activity was achieved only with 200 μM HT .	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7215722	Colon carcinoma Caco-2 cells were obtained from Leibniz Institute DSMZ (Braunschweig, Germany) and cultured in Dulbecco’s Modified Eagle Media (DMEM, Sigma, United Kingdom) supplemented with 10% FCS (Sigma, United Kingdom), 4 mM l-glutamine, 1 mM pyruvic acid, 4.5 mg/mL D-glucose, 100 units/mL potassium penicillin G, and 100 μg/mL streptomycin sulfate in a 5% CO2, 95% air humidified atmosphere.	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The present study is a first-in-human clinical trial of this microbiome-derived peptide therapeutic cancer vaccine approach in patients with follicular lymphoma (FL) and marginal zone lymphoma (MZL).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5810978	A single genotype, genogroup II and genotype 4 (GII.4), is the leading cause of acute non-bacterial gastroenteritis in humans worldwide since around 2000 .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11247842	With the information that will be generated by these functional studies, we have the potential to better understand the biological connection between identified genetic variants and mastitis resistance and develop models to integrate knowledge on regulatory variation into genomic selection schemes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Results: A total of 67 patients were recruited in the study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "A", "total", "of", "67", "patients", "were", "recruited", ...
PMC9429973	The VGPR+CR rate by investigator was 36% with ZANU vs 22% with IBR (descriptive p = 0.02) in cohort 1, and 31% in cohort 2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3915447	The physicochemical properties of the nanoparticles were characterized by various techniques, and uniform nanoparticles with an average particle size of 110±15 nm were obtained.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	Based on these results, doses between 1.0 and 1.6 mg were tested in the IberDd cohort.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Based", "on", "these", "results", ",", "dos...
PMC11541409	In a study of GIST patient samples, glucose uptake mediated by glucose transporter 1 (GLUT1) and glycolysis activity involving hexokinase-1 (HK1), lactate dehydrogenase A (LDHA), and pyruvate kinase isozyme M2 (PKM2) were found to be upregulated in high-risk tumors compared to low-risk tumors .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10926885	Numerous tumour types have elevated NDE1, which is linked to a bad prognosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Numerous", "tumour", "types", "have", "elevated", "NDE1", ",", "...
PMC8193813	Table 6 presents the average O2 and NOx measurement results and the fuel supply rate at both locations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Table", "6", "presents", "the", "avera...
PMC11045125	A. Human cord blood B cells stably infected with the ΔEBNA2 EBV mutant were co-infected with or without a retrovirus expressing mouse wild-type Myc protein as indicated and maintained on a CD40L/IL21 expressing feeder layer without antibiotic selection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11670407	Patients’ tumor information is provided in supplementary file 1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "’", "tumor", "information", "is", "provided", "in", "supplementary", "file", "1", ...
PMC9429973	Having an accurate HbF prediction may enable triage of affected children, starting effective treatments and management earlier.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Having", "an", "accurate", "HbF", "pre...
PMC9429973	They also showed significant increase in transfusion intervals for an average of 20.7 days.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "They", "also", "showed", "significant", "increase", "in", "transfusion...
PMC11629461	The plasmid pKillerRed mem which we re‐named pKillerRed PM for its plasma membrane (PM) localization was purchased from Evrogen (#FP966) (Moscow, Russia).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11395280	Indeed, we found that in human HuT78 T-ALL cells, CCL19 rapidly induced arrestin-3 mediated internalization of approximately 80% of surface CCR7, while CCL21 internalization was arrestin-3 independent and internalized less than 20% of the available CCR7 .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11541409	Journal of Clinical Oncology, 2022.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Journal", "of", "Clinical", "Oncology", ",", "2022", "." ] } ]
PMC9856122	BBI alkaloid neferine was also assessed for anti-SARS-CoV-2 activity along with other 29 compounds.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "BBI", "alkaloid", "neferine", "was", "also", "assessed", "for", ...
PMC10203589	Therefore, to some extent, FGF18 may be an important regulator in the process of potential diagnostic biomarkers for early GC diagnosis (46, 47).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11721277	Analysis time is 20.00 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Analysis", "time", "is", "20.00", "min", "." ] } ]
PMC10745221	The HCT116 and H460 cells used in this study were the parent cell lines previously described in Yamamoto et.	[ { "tags": [ "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "HCT116", "and"...
PMC10823017	Twenty-four hours post-plating, the cells were transfected using 40nM of PKC-ι, and siRNA was used to knock down the PRKCI gene.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Twenty-...
PMC11615828	Ciliated cells were then treated with 0.1% DMSO or rapamycin (Rapa, 100 nM) to trap FKBP‐tagged IFT88 onto axonemes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ciliate...
PMC10547921	Instead of using single simple molecules as their payloads, several novel strategies for designing ADCs using more complex payloads have emerged.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Instead", "o...
PMC10988555	The NTO pairs for the remainder of relevant high-energy excitations are shown in Figures S2–S5 and confirm the LLCT/ π → π* nature of the transitions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10093184	Finally, slides were washed with distilled water, counterstained with nuclear fast red (aluminium solution (0.1%, Waldeck, Münster, Germany)), dehydrated, and mounted using DPX medium (Fluka, Buchs, Switzerland).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11534035	After 15 days of treatment, the same cells were analyzed again (Figure 3E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "15", "days", "of", "treatment", ",", "t...
PMC9429973	Genomic DNA was extracted from bone marrow or peripheral blood samples at baseline and follow-up timepoints, sequencing libraries were prepared and subjected to targeted NGS on an Ion S5 Prime Sequencer (Thermo Fisher Scientific) using a panel of 38 myeloid genes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7504302	Subsequent studies have further confirmed that, along with losses, the most frequent genetic alterations in these chromosome regions are inactivating mutations found in the NF2, CDKN2A, BAP1, and TP53 tumor suppressor genes, which play pivotal roles in restricting malignant transformation .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	All patients had the same transplantation modalities: 1) Non-myeloablative conditioning regimen as described by the Baltimore’s group (Fludarabine, cyclophosphamide and 2-Gray TBI); 2) Peripheral blood stem cells (PBSC) as graft source; 3) GVHD prophylaxis using PT-Cy, cyclosporine A and mycophenolate mofetil; 4) G-CSF from day+5 to neutrophil recovery.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11026382	A slice through the structure shows the interior distribution of mutational effects on catalysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "slice", "through", "the", "structure", "shows", "the", "int...
PMC11695546	Ozoneated derivatives, which are produced when ozone reacts with unsaturated substances like oil, offer a wide range of uses because of the high volatility of ozone as a gas (Cao et al. 2017; Song et al. 2018; Ng et al. 2024).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11676674	The findings of MN frequency analyzed by ImagestreamX indicated the same profile of micronuclei frequency obtained following the analysis by fluorescent microscope at the same tested C. monspeliensis extract concentrations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11770199	Eight hours after transfection, the hMSCs-p14 as effector cells were mixed with the HCT8 or A375 cells at the ratios of 1:5, 1:12.5, and 1:25.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC10914904	These small vault RNAs play roles in targeting pathways associated with nervous system development .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "small", "vault", "RNAs", "play", "roles", "in", "target...
PMC11506827	The WST-1 assay demonstrated a significant reduction in cell viability following the GEF pre-treatment and TRAIL treatment, which was reversed by the Z-VAD-FMK pre-treatment in both cell lines (Figure 6B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11706776	Other healthy tissues (Fig. 1E) or MSCs (Fig. 1F) barely express KCNN1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Other", "healthy", "tissues", "(", "Fig.", "1E", ...
PMC11420784	Scale bar, 5 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ",", "5", "μm", "." ] } ]
PMC10158546	When applied to in vitro cultures of scrapie-infected GT1–7 and N2a cells, Amphotericin B delayed PrP accumulation yet failed to prevent prion infection when used at a relatively high concentration of 4500 ng/mL .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11727062	Additionally, gambogic acid significantly inhibits the growth of A375 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Additionally", ",", "gambogic", "acid", "significantly", "inhibits", "the", "growth", ...
PMC9429973	Clinical trial information: NCT04844866.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Clinical", "trial", "information", ":", "NCT04844866", "." ] } ]
PMC5417661	The M phase effects of NOV202 were investigated in a several human cancer cell lines of different origin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "M", "phase", "effects", "of", ...
PMC11746948	m, n Orthotopic xenograft tumors from RKO cells transplanted into the cecum of nude mice, treated with 2-BP (20 mg/kg) and a combination of 2-BP and Lip-1 (i.p.,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4443654	It is of interest to repeat this experiment with our human datasets and across multiple cell types to detect finer delineation of chromatin state beyond A and B compartmentalization.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11754094	Electroporated cells were transferred into culture vessels containing culture medium without antibiotics.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Electroporated", "cells", "were", "transferred", "into", "culture", "vessels", "contai...
PMC11519583	Scale bar: 600 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ":", "600", "μm", "." ] } ]
PMC8348645	There is evidence accumulating over the increase in the use of the medicinal plant worldwide and serving as the source to produce drugs .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There",...
PMC11574029	Targeted NOTCH3 T24 cells (G) and 5637 cells (H) were injected into the tail vein of mice, and bioluminescence imaging was used to statistically analyze the luminescence intensity in the lungs of the mice.	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11742431	After treating 3D tumor spheroids with KVN and K14N proteins for a certain time and observing the changes of 3D tumor spheres, it was found that both KVN and K14N proteins could effectively inhibit the volume of tumor spheres.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4485786	Growth arrest and block of cytokinesis induced by a single dose of IFN-γ/TNF in diverse cell lines from multiple cancers, including glioblastoma, neuroblastoma, breast cancer, hepatocellular carcinoma, and colorectal carcinoma, strongly suggests senescence and differentiation as a new but ubiquitous mechanism of immune-regulated cancer control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11438317	Similarly, phosphorylation of LCK in Y394 and Y493 are shown.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Similarly", ",", "phosphorylation", "of", "LCK", "in", "Y394", "and", "Y493", "are", ...
PMC10988808	Clear cell renal cell carcinoma (ccRCC) is one of the most prevalent renal cancers, and the molecular mechanisms underlying its progression are still not fully understood.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8068766	The pathways enriched in lists with positive DEG scores (DEG scores > 1) indicate that the relevant genes were relatively upregulated in HepG2-2.2.15 when normalized to HepG2 cells within Se– vs. Se+ comparisons.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11543885	This may take several hours dependent on vacuum performance.41.Resuspend the peptides in 20 μL of solution A and store at −80°C until further analysis.42.Transfer the purified peptide into the glass vial and place it in the LC autosampler.43.Set up the orbitrap fusion Lumos mass spectrometry instrument with the parameters described in the materials and equipment setup section.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11653168	Such an approach provides a new option for T-ALL therapy that targets STAT3 signaling, a critical pathway in the pathogenesis of numerous malignancies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC4443654	Many of the variables examined here are heavily interdependent, and for example co-occur in clusters denoting functional chromatin states .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Many", "of", "the", "v...
PMC8633974	Furthermore, early-stage success of Intellia's Clinical Trial (NCT04601051) for in vivo CRISPR Cas9 editing for patients with hereditary transthyretin amyloidosis with polyneuropathy (ATTRv-PN) and shows the promise of using in vivo gene therapy .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10317042	Prior to treatment, mice were randomly assigned to treatment cohorts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Prior", "to", "treatment", ",", "mice", "were", "randomly", "assigned", "to", "treatm...
PMC11718031	Next, cells were passaged in a 250 mL shake flask with 100 mL working volume in CD-CHO basal medium.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Next", ",", "cells", "...
PMC11599565	If this theoretical “ovarian-annex resident neuronal lineage cell” has the full quality of a neuron or its precursors, how do they gain the epithelial condition?	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8524093	Several contributions have been made to understand the mechanisms associated to virus replication and pathogenesis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Several", "contributions", "have", "been", "made", "to", "u...
PMC7215832	Exposure to RX-3117 did not affect MTX uptake at pH 5.5.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Exposure", "to", "RX-3117", "did", "not", "affect", "MTX", "uptake", "at", "pH", ...
PMC10142392	In another example, multi-arm star polymer AB3 (A = PAzo, B = PEG) had a hydrophobic/hydrophilic ratio of 78/22, slightly outside the typical range for polymersome formation, but was nevertheless found to be well suited for polymersome assembly.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Rate of incident VTE among age- and sex-matched population residing in Olmsted County, MN from 2001-2015 was pulled from the Rochester Epidemiology Project.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11621565	After 30 min, the Stop Solution was added, and the OD of the plates was read by a microplate reader at an absorbance of 490 nm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11267036	For example, RIG-I acts as a tumor inhibitor via enhancing STAT1 activation in hepatocellular carcinoma and acute myeloid leukemia .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "example", ",", ...
PMC10040136	TGF-β inhibitors but not CXCR4 and TNF-α inhibitors antagonize co-culture-induced GIST resistance (A–C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TGF-β", "inhibitors", "but", "not", "CXCR4", ...
PMC10988808	All quantitative results are presented as mean ± standard deviation (SD).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "quantitative", "results", "are", "presented", "as", "mean", "±", ...
PMC11753435	All data were reported as average values with error bars representing SD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "data", "were", "reported", "as", "average", "values", "with", "error", ...
PMC10968586	Hepatocellular carcinoma (HCC) or hepatoma is the most frequent primary liver tumor and the sixth most common cancer worldwide, with a very modest survival rate and a complex management .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6835428	To attenuate this limitation, cationic lipids are often combined with non-cationic lipids such as DOPE, which display enhanced fusogenic activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "attenu...
PMC8806312	Survival-dependent receiver operating characteristic (ROC) curves for validation of prognostic value of the prognostic index. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Survival-dependent", "receiver", "operating", ...
PMC10196713	Total RNA was isolated using Sepasol-RNA I SuperG (Nacalai Tesque, Inc.) and subjected to reverse transcription to synthesize cDNA using a PrimeScript RT Reagent Kit (Takara Bio, Inc.).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Neoantigens were identified and analysed using the Roche/Foundation Medicine neoantigen pipeline where NAB is defined as the total number of predicted neoantigens per patient.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11180402	TET1 and TET2 detection involved membrane trimming prior to antibody incubation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TET1", "and", "TET2", "detection", "involved", "membrane", "trimming", "prior", "to", ...
PMC9388315	They also reported that when siRNA was used to inhibit LDHA gene expression, in addition to inhibiting glucose uptake into cell cytoplasm and lactate production, it can reduce cell growth and prevent overexpression of ErbB2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6934009	The acidic autophagic vacuole formation in A427 cells on treatment with wogonin was detected by fluorescence microscopy (Figure 6A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "acidic"...
PMC11499381	B,C,E,F) quantified intensity of the HA (AF-568; B, E) or myc (AF-647; C, F) signal within each independent experiment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11486946	One of the possible reasons why EGFR-targeted TKIs can be detected by mobility-based screening is described in Fig. 6a.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "of", "the", "possible", ...
PMC9611901	Some of the DNA damage detectable by the assay is also due to DNA repair processes causing additional lesions .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Some", "of", "the", "DNA", ...
PMC11591794	The most important side effect requiring dose limitation is cardiotoxicity and may occur in bone marrow suppression .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "most", "important", "side", "effect", ...
PMC9429973	As predicted, HSCT recipients displayed a less diverse TCR repertoire compared with HC as revealed by higher Simpson clonality (p= 0.0079).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9219615	Similarly, phosphorylation of Src kinases Src, Fyn, Yes, Lck, Lyn, Fgr, Blk, and Hck were detected using the Milliplex MAP 8-Plex human Src family kinase kit (Millipore).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10212663	Therefore, in our study, to exclude the interference of this synergistic effect in determining the direct tumor suppressive efficacy of denosumab, patients treated with denosumab combined with immunotherapy were excluded from analyses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11320834	Further development of this combination was not explored due to dose-limiting hematological adverse events and the resulting subtherapeutic MTD .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Further", "development", "of", "t...
PMC9874064	Data were retrieved from TCGA datasets (http://gepia.cancer-pku.cn/).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "were", "retrieved", "from", "TCGA", "datasets", "(", "http://gepia.cancer-pku.cn/", ")", "." ] ...
PMC9341513	In the simulations, the interactions of the promoter are driven by binding (and molecular bridging) of active proteins; this bridging is likely further promoted by CTCF/cohesion-driven loop extrusion.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11075223	It was found that the administration group had a significant effect on lipid metabolism pathways, especially alpha-linolenic acid metabolism, fatty acid metabolism and biosynthesis of unsaturated fatty acids.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11224020	Of note, this actin cloud was only observed when cells were fixed under confinement and was positioned on top or on either side of the nucleus (Fig. 3a and Extended Data Fig. 3a,b).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8740518	The aim of this study was to identify plasma metabolic biomarkers for better MM diagnosis and prognosis by use of a MM cell line-derived xenograft (CDX) model.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	It is defined by absence of neutrophil recovery (>500 ANC) on day +28.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "defined", "by", "absence", "of"...
PMC11001582	f, Western blotting analysis of C9orf72 protein levels in brain (left panel) and spinal cord (right panel) of WT, (GR)400 and (PR)400 mice at 3 months of age.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11640555	The use of therapies aimed at inhibiting the NT/Trk signaling pathway is promising to elicit an immune response against cancer reporting how NTs afford differential survival, proliferation, and tumorigenesis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10831439	Data were obtained after gating on live (viability dye−, VD−) lymphocytes (FSC-A vs SSC-A) and singlets (SSC-A vs SSC-W). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11190538	Therefore, the abovementioned results could confirm the viability and validity of the prepared yoghurt for over 14 days, the standard period for refrigerated yoghurt storage with the stability of C-PC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10317042	Several studies have reported that JQ1, a BET inhibitor (BETi), is effective in sarcoma cell lines (19, 20).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10812665	The cellular need for ATP argues for a high glycolytic rate, while the overload with NADH rather suggests that glycolysis should be reduced.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC10502403

In the stimulated state, IFN-γ production was more dependent on ATP synthesis, which was supported by the higher OXPHOS gene expression observed in αβ-TCR-transduced γδ-T cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10968586

Moreover, in hypoxic MCF-7 cells, 75–200 μM HT reduced the amount of PARP-1, a DNA-binding protein involved in oxidative stress response, but inhibition of PARP-1 activity was achieved only with 200 μM HT .

[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7215722

Colon carcinoma Caco-2 cells were obtained from Leibniz Institute DSMZ (Braunschweig, Germany) and cultured in Dulbecco’s Modified Eagle Media (DMEM, Sigma, United Kingdom) supplemented with 10% FCS (Sigma, United Kingdom), 4 mM l-glutamine, 1 mM pyruvic acid, 4.5 mg/mL D-glucose, 100 units/mL potassium penicillin G, and 100 μg/mL streptomycin sulfate in a 5% CO2, 95% air humidified atmosphere.

[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

The present study is a first-in-human clinical trial of this microbiome-derived peptide therapeutic cancer vaccine approach in patients with follicular lymphoma (FL) and marginal zone lymphoma (MZL).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC5810978

A single genotype, genogroup II and genotype 4 (GII.4), is the leading cause of acute non-bacterial gastroenteritis in humans worldwide since around 2000 .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11247842

With the information that will be generated by these functional studies, we have the potential to better understand the biological connection between identified genetic variants and mastitis resistance and develop models to integrate knowledge on regulatory variation into genomic selection schemes.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Results: A total of 67 patients were recruited in the study.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "A", "total", "of", "67", "patients", "were", "recruited", ...

PMC9429973

The VGPR+CR rate by investigator was 36% with ZANU vs 22% with IBR (descriptive p = 0.02) in cohort 1, and 31% in cohort 2.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC3915447

The physicochemical properties of the nanoparticles were characterized by various techniques, and uniform nanoparticles with an average particle size of 110±15 nm were obtained.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC9429973

Based on these results, doses between 1.0 and 1.6 mg were tested in the IberDd cohort.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Based", "on", "these", "results", ",", "dos...

PMC11541409

In a study of GIST patient samples, glucose uptake mediated by glucose transporter 1 (GLUT1) and glycolysis activity involving hexokinase-1 (HK1), lactate dehydrogenase A (LDHA), and pyruvate kinase isozyme M2 (PKM2) were found to be upregulated in high-risk tumors compared to low-risk tumors .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10926885

Numerous tumour types have elevated NDE1, which is linked to a bad prognosis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Numerous", "tumour", "types", "have", "elevated", "NDE1", ",", "...

PMC8193813

Table 6 presents the average O2 and NOx measurement results and the fuel supply rate at both locations.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Table", "6", "presents", "the", "avera...

PMC11045125

A. Human cord blood B cells stably infected with the ΔEBNA2 EBV mutant were co-infected with or without a retrovirus expressing mouse wild-type Myc protein as indicated and maintained on a CD40L/IL21 expressing feeder layer without antibiotic selection.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11670407

Patients’ tumor information is provided in supplementary file 1.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "’", "tumor", "information", "is", "provided", "in", "supplementary", "file", "1", ...

PMC9429973

Having an accurate HbF prediction may enable triage of affected children, starting effective treatments and management earlier.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Having", "an", "accurate", "HbF", "pre...

PMC9429973

They also showed significant increase in transfusion intervals for an average of 20.7 days.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "They", "also", "showed", "significant", "increase", "in", "transfusion...

PMC11629461

The plasmid pKillerRed mem which we re‐named pKillerRed PM for its plasma membrane (PM) localization was purchased from Evrogen (#FP966) (Moscow, Russia).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11395280

Indeed, we found that in human HuT78 T-ALL cells, CCL19 rapidly induced arrestin-3 mediated internalization of approximately 80% of surface CCR7, while CCL21 internalization was arrestin-3 independent and internalized less than 20% of the available CCR7 .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...

PMC11541409

Journal of Clinical Oncology, 2022.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Journal", "of", "Clinical", "Oncology", ",", "2022", "." ] } ]

PMC9856122

BBI alkaloid neferine was also assessed for anti-SARS-CoV-2 activity along with other 29 compounds.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "BBI", "alkaloid", "neferine", "was", "also", "assessed", "for", ...

PMC10203589

Therefore, to some extent, FGF18 may be an important regulator in the process of potential diagnostic biomarkers for early GC diagnosis (46, 47).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11721277

Analysis time is 20.00 min.

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Analysis", "time", "is", "20.00", "min", "." ] } ]

PMC10745221

The HCT116 and H460 cells used in this study were the parent cell lines previously described in Yamamoto et.

[ { "tags": [ "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "HCT116", "and"...

PMC10823017

Twenty-four hours post-plating, the cells were transfected using 40nM of PKC-ι, and siRNA was used to knock down the PRKCI gene.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Twenty-...

PMC11615828

Ciliated cells were then treated with 0.1% DMSO or rapamycin (Rapa, 100 nM) to trap FKBP‐tagged IFT88 onto axonemes.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ciliate...

PMC10547921

Instead of using single simple molecules as their payloads, several novel strategies for designing ADCs using more complex payloads have emerged.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Instead", "o...

PMC10988555

The NTO pairs for the remainder of relevant high-energy excitations are shown in Figures S2–S5 and confirm the LLCT/ π → π* nature of the transitions.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10093184

Finally, slides were washed with distilled water, counterstained with nuclear fast red (aluminium solution (0.1%, Waldeck, Münster, Germany)), dehydrated, and mounted using DPX medium (Fluka, Buchs, Switzerland).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11534035

After 15 days of treatment, the same cells were analyzed again (Figure 3E).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "15", "days", "of", "treatment", ",", "t...

PMC9429973

Genomic DNA was extracted from bone marrow or peripheral blood samples at baseline and follow-up timepoints, sequencing libraries were prepared and subjected to targeted NGS on an Ion S5 Prime Sequencer (Thermo Fisher Scientific) using a panel of 38 myeloid genes.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7504302

Subsequent studies have further confirmed that, along with losses, the most frequent genetic alterations in these chromosome regions are inactivating mutations found in the NF2, CDKN2A, BAP1, and TP53 tumor suppressor genes, which play pivotal roles in restricting malignant transformation .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

All patients had the same transplantation modalities: 1) Non-myeloablative conditioning regimen as described by the Baltimore’s group (Fludarabine, cyclophosphamide and 2-Gray TBI); 2) Peripheral blood stem cells (PBSC) as graft source; 3) GVHD prophylaxis using PT-Cy, cyclosporine A and mycophenolate mofetil; 4) G-CSF from day+5 to neutrophil recovery.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11026382

A slice through the structure shows the interior distribution of mutational effects on catalysis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "slice", "through", "the", "structure", "shows", "the", "int...

PMC11695546

Ozoneated derivatives, which are produced when ozone reacts with unsaturated substances like oil, offer a wide range of uses because of the high volatility of ozone as a gas (Cao et al. 2017; Song et al. 2018; Ng et al. 2024).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11676674

The findings of MN frequency analyzed by ImagestreamX indicated the same profile of micronuclei frequency obtained following the analysis by fluorescent microscope at the same tested C. monspeliensis extract concentrations.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11770199

Eight hours after transfection, the hMSCs-p14 as effector cells were mixed with the HCT8 or A375 cells at the ratios of 1:5, 1:12.5, and 1:25.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O"...

PMC10914904

These small vault RNAs play roles in targeting pathways associated with nervous system development .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "small", "vault", "RNAs", "play", "roles", "in", "target...

PMC11506827

The WST-1 assay demonstrated a significant reduction in cell viability following the GEF pre-treatment and TRAIL treatment, which was reversed by the Z-VAD-FMK pre-treatment in both cell lines (Figure 6B).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11706776

Other healthy tissues (Fig. 1E) or MSCs (Fig. 1F) barely express KCNN1.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Other", "healthy", "tissues", "(", "Fig.", "1E", ...

PMC11420784

Scale bar, 5 μm.

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ",", "5", "μm", "." ] } ]

PMC10158546

When applied to in vitro cultures of scrapie-infected GT1–7 and N2a cells, Amphotericin B delayed PrP accumulation yet failed to prevent prion infection when used at a relatively high concentration of 4500 ng/mL .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...

PMC11727062

Additionally, gambogic acid significantly inhibits the growth of A375 cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Additionally", ",", "gambogic", "acid", "significantly", "inhibits", "the", "growth", ...

PMC9429973

Clinical trial information: NCT04844866.

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Clinical", "trial", "information", ":", "NCT04844866", "." ] } ]

PMC5417661

The M phase effects of NOV202 were investigated in a several human cancer cell lines of different origin.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "M", "phase", "effects", "of", ...

PMC11746948

m, n Orthotopic xenograft tumors from RKO cells transplanted into the cecum of nude mice, treated with 2-BP (20 mg/kg) and a combination of 2-BP and Lip-1 (i.p.,

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC4443654

It is of interest to repeat this experiment with our human datasets and across multiple cell types to detect finer delineation of chromatin state beyond A and B compartmentalization.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11754094

Electroporated cells were transferred into culture vessels containing culture medium without antibiotics.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Electroporated", "cells", "were", "transferred", "into", "culture", "vessels", "contai...

PMC11519583

Scale bar: 600 μm.

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ":", "600", "μm", "." ] } ]

PMC8348645

There is evidence accumulating over the increase in the use of the medicinal plant worldwide and serving as the source to produce drugs .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There",...

PMC11574029

Targeted NOTCH3 T24 cells (G) and 5637 cells (H) were injected into the tail vein of mice, and bioluminescence imaging was used to statistically analyze the luminescence intensity in the lungs of the mice.

[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...

PMC11742431

After treating 3D tumor spheroids with KVN and K14N proteins for a certain time and observing the changes of 3D tumor spheres, it was found that both KVN and K14N proteins could effectively inhibit the volume of tumor spheres.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC4485786

Growth arrest and block of cytokinesis induced by a single dose of IFN-γ/TNF in diverse cell lines from multiple cancers, including glioblastoma, neuroblastoma, breast cancer, hepatocellular carcinoma, and colorectal carcinoma, strongly suggests senescence and differentiation as a new but ubiquitous mechanism of immune-regulated cancer control.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11438317

Similarly, phosphorylation of LCK in Y394 and Y493 are shown.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Similarly", ",", "phosphorylation", "of", "LCK", "in", "Y394", "and", "Y493", "are", ...

PMC10988808

Clear cell renal cell carcinoma (ccRCC) is one of the most prevalent renal cancers, and the molecular mechanisms underlying its progression are still not fully understood.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8068766

The pathways enriched in lists with positive DEG scores (DEG scores > 1) indicate that the relevant genes were relatively upregulated in HepG2-2.2.15 when normalized to HepG2 cells within Se– vs. Se+ comparisons.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11543885

This may take several hours dependent on vacuum performance.41.Resuspend the peptides in 20 μL of solution A and store at −80°C until further analysis.42.Transfer the purified peptide into the glass vial and place it in the LC autosampler.43.Set up the orbitrap fusion Lumos mass spectrometry instrument with the parameters described in the materials and equipment setup section.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11653168

Such an approach provides a new option for T-ALL therapy that targets STAT3 signaling, a critical pathway in the pathogenesis of numerous malignancies.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC4443654

Many of the variables examined here are heavily interdependent, and for example co-occur in clusters denoting functional chromatin states .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Many", "of", "the", "v...

PMC8633974

Furthermore, early-stage success of Intellia's Clinical Trial (NCT04601051) for in vivo CRISPR Cas9 editing for patients with hereditary transthyretin amyloidosis with polyneuropathy (ATTRv-PN) and shows the promise of using in vivo gene therapy .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10317042

Prior to treatment, mice were randomly assigned to treatment cohorts.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Prior", "to", "treatment", ",", "mice", "were", "randomly", "assigned", "to", "treatm...

PMC11718031

Next, cells were passaged in a 250 mL shake flask with 100 mL working volume in CD-CHO basal medium.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Next", ",", "cells", "...

PMC11599565

If this theoretical “ovarian-annex resident neuronal lineage cell” has the full quality of a neuron or its precursors, how do they gain the epithelial condition?

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8524093

Several contributions have been made to understand the mechanisms associated to virus replication and pathogenesis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Several", "contributions", "have", "been", "made", "to", "u...

PMC7215832

Exposure to RX-3117 did not affect MTX uptake at pH 5.5.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Exposure", "to", "RX-3117", "did", "not", "affect", "MTX", "uptake", "at", "pH", ...

PMC10142392

In another example, multi-arm star polymer AB3 (A = PAzo, B = PEG) had a hydrophobic/hydrophilic ratio of 78/22, slightly outside the typical range for polymersome formation, but was nevertheless found to be well suited for polymersome assembly.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Rate of incident VTE among age- and sex-matched population residing in Olmsted County, MN from 2001-2015 was pulled from the Rochester Epidemiology Project.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC11621565

After 30 min, the Stop Solution was added, and the OD of the plates was read by a microplate reader at an absorbance of 490 nm.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11267036

For example, RIG-I acts as a tumor inhibitor via enhancing STAT1 activation in hepatocellular carcinoma and acute myeloid leukemia .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "example", ",", ...

PMC10040136

TGF-β inhibitors but not CXCR4 and TNF-α inhibitors antagonize co-culture-induced GIST resistance (A–C).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TGF-β", "inhibitors", "but", "not", "CXCR4", ...

PMC10988808

All quantitative results are presented as mean ± standard deviation (SD).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "quantitative", "results", "are", "presented", "as", "mean", "±", ...

PMC11753435

All data were reported as average values with error bars representing SD.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "data", "were", "reported", "as", "average", "values", "with", "error", ...

PMC10968586

Hepatocellular carcinoma (HCC) or hepatoma is the most frequent primary liver tumor and the sixth most common cancer worldwide, with a very modest survival rate and a complex management .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC6835428

To attenuate this limitation, cationic lipids are often combined with non-cationic lipids such as DOPE, which display enhanced fusogenic activity.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "attenu...

PMC8806312

Survival-dependent receiver operating characteristic (ROC) curves for validation of prognostic value of the prognostic index. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Survival-dependent", "receiver", "operating", ...

PMC10196713

Total RNA was isolated using Sepasol-RNA I SuperG (Nacalai Tesque, Inc.) and subjected to reverse transcription to synthesize cDNA using a PrimeScript RT Reagent Kit (Takara Bio, Inc.).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Neoantigens were identified and analysed using the Roche/Foundation Medicine neoantigen pipeline where NAB is defined as the total number of predicted neoantigens per patient.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11180402

TET1 and TET2 detection involved membrane trimming prior to antibody incubation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TET1", "and", "TET2", "detection", "involved", "membrane", "trimming", "prior", "to", ...

PMC9388315

They also reported that when siRNA was used to inhibit LDHA gene expression, in addition to inhibiting glucose uptake into cell cytoplasm and lactate production, it can reduce cell growth and prevent overexpression of ErbB2.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC6934009

The acidic autophagic vacuole formation in A427 cells on treatment with wogonin was detected by fluorescence microscopy (Figure 6A).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "acidic"...

PMC11499381

B,C,E,F) quantified intensity of the HA (AF-568; B, E) or myc (AF-647; C, F) signal within each independent experiment.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11486946

One of the possible reasons why EGFR-targeted TKIs can be detected by mobility-based screening is described in Fig. 6a.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "of", "the", "possible", ...

PMC9611901

Some of the DNA damage detectable by the assay is also due to DNA repair processes causing additional lesions .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Some", "of", "the", "DNA", ...

PMC11591794

The most important side effect requiring dose limitation is cardiotoxicity and may occur in bone marrow suppression .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "most", "important", "side", "effect", ...

PMC9429973

As predicted, HSCT recipients displayed a less diverse TCR repertoire compared with HC as revealed by higher Simpson clonality (p= 0.0079).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC9219615

Similarly, phosphorylation of Src kinases Src, Fyn, Yes, Lck, Lyn, Fgr, Blk, and Hck were detected using the Milliplex MAP 8-Plex human Src family kinase kit (Millipore).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10212663

Therefore, in our study, to exclude the interference of this synergistic effect in determining the direct tumor suppressive efficacy of denosumab, patients treated with denosumab combined with immunotherapy were excluded from analyses.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11320834

Further development of this combination was not explored due to dose-limiting hematological adverse events and the resulting subtherapeutic MTD .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Further", "development", "of", "t...

PMC9874064

Data were retrieved from TCGA datasets (http://gepia.cancer-pku.cn/).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "were", "retrieved", "from", "TCGA", "datasets", "(", "http://gepia.cancer-pku.cn/", ")", "." ] ...

PMC9341513

In the simulations, the interactions of the promoter are driven by binding (and molecular bridging) of active proteins; this bridging is likely further promoted by CTCF/cohesion-driven loop extrusion.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11075223

It was found that the administration group had a significant effect on lipid metabolism pathways, especially alpha-linolenic acid metabolism, fatty acid metabolism and biosynthesis of unsaturated fatty acids.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11224020

Of note, this actin cloud was only observed when cells were fixed under confinement and was positioned on top or on either side of the nucleus (Fig. 3a and Extended Data Fig. 3a,b).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8740518

The aim of this study was to identify plasma metabolic biomarkers for better MM diagnosis and prognosis by use of a MM cell line-derived xenograft (CDX) model.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

It is defined by absence of neutrophil recovery (>500 ANC) on day +28.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "defined", "by", "absence", "of"...

PMC11001582

f, Western blotting analysis of C9orf72 protein levels in brain (left panel) and spinal cord (right panel) of WT, (GR)400 and (PR)400 mice at 3 months of age.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11640555

The use of therapies aimed at inhibiting the NT/Trk signaling pathway is promising to elicit an immune response against cancer reporting how NTs afford differential survival, proliferation, and tumorigenesis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10831439

Data were obtained after gating on live (viability dye−, VD−) lymphocytes (FSC-A vs SSC-A) and singlets (SSC-A vs SSC-W). (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11190538

Therefore, the abovementioned results could confirm the viability and validity of the prepared yoghurt for over 14 days, the standard period for refrigerated yoghurt storage with the stability of C-PC.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10317042

Several studies have reported that JQ1, a BET inhibitor (BETi), is effective in sarcoma cell lines (19, 20).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC10812665

The cellular need for ATP argues for a high glycolytic rate, while the overload with NADH rather suggests that glycolysis should be reduced.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...