OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC11483468	GST-TAT-LPTS39 protein inhibition of telomerase activity was measured by the TRAP assay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GST-TAT-LPTS39", "protein", "inhibition", "of", "telomerase", "activity", "was", "meas...
PMC10758402	Subsequently, the viral sensitizing potential of DMF in impacting HSV.n212 viral titers was evaluated in several cancer subtypes including breast (murine 4T1), colon (murine CT26.wt, human HT29), glioma (murine CT2A), sarcoma (murine S180), renal (human 786-0) and melanoma (patient derived OHRI-13) where we observed a significant increase compared to HSV.n212 alone ( Figures 1B, C ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11787381	control (white) = 109 ± 3 Neun+ cells/field).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "control", "(", "white", ")", "=", "109", "±", "3", "Neun+", "cells/field", ")",...
PMC6889484	For detection of P2A, the rabbit anti-P2A antibody (catalog #ABS31, Sigma) was used at a 1:10,000 dilution.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "detec...
PMC7602170	The authors suggested that programmed cell death may be avoided in the pathogenesis of GISTs .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "authors", "suggested", "that", "programmed", "cell", ...
PMC9429973	Results: Ninety-five patients, 65 (68.4%) from ICESP and 30 (31.6%) from HC-UFMG fulfilled the study criteria.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11518702	The extent to which these outcomes may involve strengthened adhesion will also be informative to establish.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "extent", "to", "which", "these", "outcomes", ...
PMC10158546	Kill curve with puromycin antibiotic on non-treated ReN cells revealed a concentration of 0.5 µg/mL was sufficient to kill all cells after 48 hours. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC6771295	In Mero-14 cells, SIRT3 silencing increased SIRT1 protein levels in untreated cells (Figure 3Bi, compare bar 1 to 5) and decreased SIRT5 protein levels in etoposide and resveratrol treated cells (Figure 3Biii, compare bars 3 and 4 to 7 and 8).	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11742864	Kristina Rogers et al. showed that DHA can alter epidermal growth factor receptor (EGFR)-associated signaling by disrupting its lipid raft binding, thus enhancing the efficacy of EGFR inhibitors and inhibiting tumor growth in lung cancer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11024707	In studies carried out previously, it was reported that miRNA-151a regulates close homolog of L1 (CHL1) playing a role in neural cell proliferation, differentiation, and axon guidance .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11604768	Each set of connect dots represents a single promoter.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "set", "of", "connect", "dots", "represents", "a", "single", "promoter", "." ] } ]
PMC7433824	Additionally, there is a growing interest in the potential antineoplastic of P4 in GBM. , ,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "there", "is", "a", "gr...
PMC9429973	Baseline QoL was dramatically impaired by the majority of SF-36 scales; 42% patients experienced severe/critical QoL impairment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Baseline", "QoL", "was", "dramati...
PMC9429973	Aims: The dynamics of CAR-T quantity and subtypes in PBS were evaluated, and correlated with responsiveness to treatment and treatment-related toxicities.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ...
PMC11269933	Specifically, the phosphorylation level of Ser11 in C. angulata was significantly upregulated (p < 0.05, 2.8-fold), while it showed a slight increase in C. gigas (1.63-fold).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11742231	IMIPMF demonstrates high performance with a reliable AUC value, highlighting its effectiveness despite only considering known miRNA-disease associations and miRNA expression data.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "IMIPMF"...
PMC11487720	The L929S cell stable transfectant, expressing EGFP-TRAF2(124–233), strongly resisted UV/cold shock-induced BCD.	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "L929S", "cell", "stable", "transfectant", ",", ...
PMC9429973	According to the bioinformatics analysis, FGF/FGFR3 was the most significant signaling pathway for PMBCL in our study, because it is able to activate all listed pathways via FGFR-receptor activation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10808409	Similar results have been reported.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Similar", "results", "have", "been", "reported", "." ] } ]
PMC11534035	Cells were cultured under consistent conditions, in a humidified atmosphere at 37˚C with 5% CO2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "cultured", "under", "consistent"...
PMC11522251	Conversely, the excessive expression of HOXB8 reduced the growth suppression in SW48 cells caused by cetuximab by triggering the STAT3 signaling pathway.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11323699	Statistical analysis was performed using the Gehan–Breslow–Wilcoxon test, denoted as p < 0.05 and **p < 0.001 Efficacy of a sequential combination of olaparib with TAX2 in a peritoneal carcinomatosis model.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8140214	They have different actions including antiallergic, anti-inflammatory, antiseptic, and antioxidant, and exert limited toxicity (Choi et al., 2017 ▶; Srivastava et al., 2016 ▶).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11541409	Therapeutic antibodies block the binding of ligands to their cognate receptors and induce antibody/complement-dependent cell cytotoxicity (ADCC/CDC) (Fig. 3C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therape...
PMC9429973	However, one month later, a right submandibular adenomegaly appeared.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "one", "month", "later", ",", "a", "right", "submandibular", "adenomeg...
PMC11201989	Upon activation of the Hh pathway, Smo accumulates in the cilium, resulting in the cilia accumulation of Gli2/3 associated with the production of Gli activators .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11240448	These cSTAR models suggested strategies of normalizing phosphorylation networks of BC cell lines using small molecule inhibitors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "cSTAR", "models", "suggested", "strategi...
PMC10490530	After establishing the pNF-κB–hLuz sensor, we decided to combine the p53-NLuc and pPIK3CA-FLuc2-tdT sensors to study a complex gene regulation of PIK3CA promoter by p53 and NF-κB (Figure 4a).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Image: Summary/Conclusion: Our overall positivity rate was 28.4% which includes mutations in any hereditary cancer gene, and 11.2% for HHDs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	Mobilization failure was only seen in group A, (n=14, 17%, P=0.006).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mobilization", "failure", "was", "only", "seen", ...
PMC10589262	The surface expression of MT-KIT in GIST430 cells was higher than in GIST882 cells due to the heterozygous mutation in GIST430 cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": ...
PMC11487720	UV irradiation induces WWOXf cells to undergo bubbling cell death (BCD) — an event due to the accumulation of nuclear nitric oxide (NO) gas that forcefully pushes the nuclear and cell membranes to form one or two bubbles at room temperature (22 °C) and below.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11469524	Therefore, time-series experiments were performed to determine the optimal time point for the pathway intervention experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "time-series", "experiments", "w...
PMC8041314	Twenty microliters of the dilutions of the compounds in KHB were pipetted into black 96-well plates (Greiner, Frickenhausen, Germany).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Twenty"...
PMC11665584	The macrophage subtypes shared common myeloid lineage markers H2-Eb1 and Cd74 (Supplemental Figure 7B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "macrophage", "subtypes", "shared", "common", "m...
PMC9429973	Patients living with PNH can experience anemia with associated fatigue, dyspnea, and require blood cell transfusions which can negatively impact quality of life (QoL).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11665584	Whereas the skin sample keratinocyte populations were roughly divided between IFE and hair follicle (HF) populations (control: 48% IFE, 37% HF; PITX1: 45% IFE, 39% HF), oral keratinocytes were only divided on stratified epithelial subtypes, reflecting the lack of hair follicles.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11765678	Because many of the clinically active anticancer drugs currently used in the clinic are substrates of ABC transporters, treatment failure often results in poor prognosis and ultimately increased mortality.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11400680	To be a fair comparison, we select mAP50, mAP75, and mAP50–95 as standard assessment criteria because all the methods that we compared used them.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Additional data with longer follow-up, including subgroup analyses and progression-free survival, will be presented.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additional", "data", "with", "longer", "follow-up", ",...
PMC11420784	After the initial infection, recurrence occurs in 25% of patients within 6 months, with 68% of recurrent infections caused by the original strain, despite the use of appropriate antibiotic therapy .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11543853	The cytoplasmic genome release may have a higher probability of resulting in successful infection than the endosomal one, because the RNases released from endosomes disperse in the cell cytoplasm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10652261	The release of phosphatidylserine from apoptotic cells inside the healthy cell membranes via disintegration of the cell membrane can be observed with Annexin V–PI to show late stages of cell death, or necrotic cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9428827	Although different tumors induce different suppressive mechanisms (17), we have previously studied that all the tumors used in the present work expand Tregs on mouse spleens above the normal levels, even when other suppressive populations can also be expanded.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10114490	Following the protocol depicted in Fig. 1, we obtained diHLC-T. Dox addition induced a drastic change in morphology manifested by lose of elongated morphology and acquisition of a compact polygonal cell mass (Additional file 1: Fig. S6A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11574271	A control plasmid containing a scramble shRNA was also used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "control", "plasmid", "containing", "a", "scramble", "shRNA", "was", "also", "used", "...
PMC11794847	8HVEM regulates GPT2 by interacting with its upstream transcription factor FOXA2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "8HVEM", "regulates", "GPT2", "by", "interacting", "with", "its", "upstream", "transcription...
PMC11767582	Cytotoxicity of the series of cis-restricted triazole analogues of CA-4 was investigated as described in the Materials and Methods section by growth inhibition assays, using two types of tumor cells, namely, the human colon cancer cell line HT-29 and human lung cancer cell line A-549, as well as one normal cell line, the human embryonic kidney cell line HEK-293 , as a way to estimate the selectivity of the compounds for tumor cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11495567	EGFR signals are passed on to rat sarcoma virus (RAS) proteins through such intermediates as growth factor receptor binding proteins and son-of-sevenless (SOS), a guanine nucleotide exchange factor (GEF) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11420784	This result may be due to a defect in the bacteria to escape fusiform vesicles in the absence of PldA. Consistent with in vitro results, the number of exocytosed bacteria in ΔpldA-infected BALB/c mouse bladders increased compared to that of the WT or ΔpldA+ at 6 hpi.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6684588	Peak tetanic force generated by ACE-083-injected or uninjected (contralateral) TA muscles as determined in situ.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Peak", "tetanic", "force", "generated", "by", ...
PMC11285179	As expected, CEBPB expression strongly correlated with CCL28 (Fig. 1F).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "expected", ",", "CEBPB", "expression", "strongly", "correlated", "wit...
PMC9776316	Although the initial clinical response of ovarian cancer patients to first-line platinum-based chemotherapy is often excellent, most patients relapse and develop resistance to treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11394730	Genistein is an anti-tumoricidal molecule in different types of cancer (Figure 6); it can induce apoptosis by mediating various signaling cascades, including caspases through extrinsic and intrinsic mitochondrial pathways .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10820104	Flow cytometry was performed with the BD FACSLyric flow cytometer (#87135, BD Biosciences, Heidelberg, Germany), whereby FlowJo software (version 10.8.1) was utilized for the analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11794568	In the TCGA database, there was no significant difference between CRIP1 expression and N-stage of melanoma tissues. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "TCGA", "database", ...
PMC9424261	The antibodies used for co-IP were anti-GSS (1:200, #ab124811, Abcam) or GSS (H-7) (1:50, sc-166882, Santa Cruz), anti-MDM2 (1:200, ab259265, Abcam), anti-SYVN1 (1:200, #14773, CST) and anti-ubiquitin (1:200, #3936, CST).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9874064	The PDX model can better stand for the pathological characteristics of tumor in clinical patients, and the drug efficacy screen results on PDX models can better represent the clinic reality, hence with greater clinic translational significance .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10674574	Some culture media for the Caco-2 line may contain amino acids (1% nonessential amino acid mixture) that are essential for cell growth .	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC10048572	The target variable was the presence of LOH or EMAST at one or more of the studied loci.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "target", "variable", "was", "th...
PMC10033453	WEHI 164 cells were plated at 5e5 cells per well in a 6-well plate and incubated overnight.	[ { "tags": [ "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "WEHI", "164", "cells", "were", ...
PMC11047729	Different concentrations of curcumin were applied to the cells that were incubated for 24 h. After this time, telomerase activity was measured using TRAP assay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10024132	Data are shown as mean ± SD from four different experiments. *	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "shown", "as", "mean", "±", "SD", "from", "four", "different...
PMC10940855	Similarly, activation of EFNB2 reverse signaling has been implicated in the progression of oral squamous cell carcinoma (70), glioblastoma (64, 71), and perivascular invasion and migration, in part by mediating anchorage-independent cytokinesis through RhoA (72).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	During the study period, we found that the number of patients with efficacy data were decreasing with time (baseline=183&116, Week 16=126 & 96, Week 32=90 & 62, Week 48=38 & 19 for spleen size measurement and total symptom score, respectively).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11694625	The N–H stretching vibrations are in the range of 3173–3203 cm, and the CN stretching vibrations were observed in the region of 1589–1608 cm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9910796	In contrast, the pacmanvirus cryo-EM structure contains an inner envelope enclosed by an external capsid, but not apparently an internal capsid similar to that of ASFV and faustovirus .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11720107	Therefore, we can assume that the present data align with the current state of knowledge.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "we", "can", "assume", "that", ...
PMC11300639	The sequences of siRNA and shRNA are provided in the Table S1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "sequences", "of", "siRNA", "and", "shRNA", "are", "provided", "in", ...
PMC11087301	The involvement of stem cells is indispensable for angiogenesis, as they can differentiate into different cell types within blood vessels or release exosomes that promote the growth of new blood vessels .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11012012	Also, Farage cells (an EBV-positive diffuse large B cell lymphoma (DLBCL) cell line) were found to express high levels of SLAMF1/CD150.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973	The estimated AUC-ROCs suggest that the adjusted model is more robust in stroke, hypertension, and CKD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "estimated", "AUC-ROCs", "suggest", ...
PMC11673128	To assess any changes in CD47 RNA expression after ALKi exposure over time, we performed real-time quantitative polymerase chain reaction (qPCR).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11371747	In full contrast, protection by 5 µM l-LV of TSIA was very efficient for all three antifolates, leading to dramatic shifts (>100–1000-fold) in TSIA IC50 values when compared to conditions without LV (Table 6).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6133382	Over the last decade, multiple broadly neutralizing monoclonal antibodies (bN-mAbs) to the HIV-1 envelope protein (Env) gp120 have been described.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	Therefore, we aims to study the telomere length shortening and its correlation with the alteration of genes involved in the telomere maintenance, DNA damage, and cellular senescence in AA patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11679326	Thus, the expression of MGAT5, which catalyzes the formation of β1,6-GlcNAc-branched N-glycans, acts as a key player in ensuring migration in glioblastoma stem cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11607764	Abnormal expression of PTBP1 was involved in sustaining the development of multiple myeloma.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Abnormal", "expression", "of", "PTBP1", "was", "involved", "in", "sustainin...
PMC11694625	Finally, the precipitation was filtered, washed thoroughly with ethanol and then purified by column chromatography (petroleum ether : ethyl acetate = 1 : 1) to give yellow solid, named compound 3a, with a yield of ca.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6222726	The leaflets are typically of oval shape, 4.5 to 15 cm long and 2 to 6 cm wide, ending in a long point.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11515150	In addition, 12 C CAR-NK cells showed cell lysis properties towards normal autologous and allogeneic T cells due to CD5 expression in normal T cells, indicating that T-cell immunodeficiency would be induced by 12 C CAR-NK cells targeting T cell malignancies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	This work was supported by the Polish National Science Centre (UMO-2018/31/D/NZ5/01299).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "work", "was", "supported", "by", "the", "Polish", "National", ...
PMC11551844	The procedure was repeated to obtain concentrated solutions of AuNPs-JDH, AuNPs-JDE and AuNPs-JC-2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "procedure", "was", "repeated", "to", "obtain", "concentrated", ...
PMC11585565	As demonstrated earlier, the levels of c.1474G > T, p.(Gly492Cys) and c.1475G > A, c.1484 C > T, p.(Gly492Asp) mRNA and protein were significantly lower compared with WT and p.(Thr495Ile) protein at 48-hours after transfection (Fig. 2b-d).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9100622	The A673 cell line and A673/TR/EF1 clone were maintained in DMEM (SH30022.01; GE healthcare, Chicago, IL, USA) with 10% fetal bovine serum (Sigma-Aldrich, St. Louis, MO, USA) and 1% Penicillin/Streptomycin (Thermofisher Scientific, Waltham, MA, USA); Blasticidin (10 μg/mL; Merk, Darmstadt, Germany) and Zeocin (100 μg/mL; Invitrogen, Waltham, MA, USA) were added to A673/TR/EF1 at 37 °C with 5% CO2.	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6181431	We conclude that mTOR pathway gene mutations did not contribute to rapalog resistance development in these six patients with advanced RCC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "conclude", ...
PMC11678130	However, one of the main issues associated with the utilization of 5-FU in chemotherapy is drug resistance ; over the last twenty years, significant importance has been placed on the discovery of effective strategies to enhance tumor sensitivity to 5-FU and to overcome its clinical resistance .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11380454	The software used for all the statistical analyses was IBM SPSS Statistics 21.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "software", "used", "for", "all", "the", "statistical", "analyses", ...
PMC11565047	They grew in DMEM media supplemented with 10 % fetal bovine serum (FBS) and 1 % streptomycin, penicillin, and sodium pyruvate, and were incubated at 37 °C with 5 % CO2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11064533	To investigate whether distinct functional classes of DEGs were differentially expressed in clumps compared to planktonic culture, DEGs were assigned to functional categories based on sequence similarity (Fig. 3B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11752740	Specifically, under combination therapy, MDR1 expression decreased by approximately 95% in SK-BR3 cells, compared to reductions of 73% and 70% observed with CFZ or pistachio hull extract alone, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11473843	Drug synergism was calculated using CompuSyn software (version 1.0) (http://www.combosyn.com), which is based on the median-effect principle (Chou) and the combination index-isobologram theorem (Chou–Talalay) (Chou, 2010).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The patient received her first dose of the BNT162b2 COVID-19 Vaccine two weeks before symptom onset.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "patient", "received", "her", "first", "dose", ...
PMC9065483	Full list of hits of the kinase inhibitor high-throughput screen EGFR is a receptor tyrosine kinase found on the cellular membrane, responsible for regulation of cell proliferation and survival events.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Summary/Conclusion: In this study, there is a high level of consensus amongst laboratories in the reporting and analysis of TP53 variants, except for protein nomenclature usage.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5716223	Previous data concerning the correlation between NGF and an increased activity in cycle Krebs enzymes also involved the activation of the JNK pathway .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Previou...
PMC9895440	Source data and exact p-values are provided as a Source Data file.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Source", "data", "and", "exact", "p-values", "are", "provided", "as", "a", ...
PMC5443223	CEP164 may be phosphorylated by ataxia telangiectasia mutated (ATM) kinase and Rad3-related protein (ATR) kinase in the DNA damage response (DDR) pathway and has a key role in the gap 2/mitosis (G2/M) checkpoint (7,8).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11774747	Indeed, Atara Biotherapeutics, under the guidance of Pierre Fabre, has been at the forefront of developing EBVSTs for treating EBV-associated malignancies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11483468

GST-TAT-LPTS39 protein inhibition of telomerase activity was measured by the TRAP assay.

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PMC10758402

Subsequently, the viral sensitizing potential of DMF in impacting HSV.n212 viral titers was evaluated in several cancer subtypes including breast (murine 4T1), colon (murine CT26.wt, human HT29), glioma (murine CT2A), sarcoma (murine S180), renal (human 786-0) and melanoma (patient derived OHRI-13) where we observed a significant increase compared to HSV.n212 alone ( Figures 1B, C ).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11787381

control (white) = 109 ± 3 Neun+ cells/field).

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PMC6889484

For detection of P2A, the rabbit anti-P2A antibody (catalog #ABS31, Sigma) was used at a 1:10,000 dilution.

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PMC7602170

The authors suggested that programmed cell death may be avoided in the pathogenesis of GISTs .

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PMC9429973

Results: Ninety-five patients, 65 (68.4%) from ICESP and 30 (31.6%) from HC-UFMG fulfilled the study criteria.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11518702

The extent to which these outcomes may involve strengthened adhesion will also be informative to establish.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "extent", "to", "which", "these", "outcomes", ...

PMC10158546

Kill curve with puromycin antibiotic on non-treated ReN cells revealed a concentration of 0.5 µg/mL was sufficient to kill all cells after 48 hours. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...

PMC6771295

In Mero-14 cells, SIRT3 silencing increased SIRT1 protein levels in untreated cells (Figure 3Bi, compare bar 1 to 5) and decreased SIRT5 protein levels in etoposide and resveratrol treated cells (Figure 3Biii, compare bars 3 and 4 to 7 and 8).

[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11742864

Kristina Rogers et al. showed that DHA can alter epidermal growth factor receptor (EGFR)-associated signaling by disrupting its lipid raft binding, thus enhancing the efficacy of EGFR inhibitors and inhibiting tumor growth in lung cancer.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11024707

In studies carried out previously, it was reported that miRNA-151a regulates close homolog of L1 (CHL1) playing a role in neural cell proliferation, differentiation, and axon guidance .

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PMC11604768

Each set of connect dots represents a single promoter.

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PMC7433824

Additionally, there is a growing interest in the potential antineoplastic of P4 in GBM. , ,

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PMC9429973

Baseline QoL was dramatically impaired by the majority of SF-36 scales; 42% patients experienced severe/critical QoL impairment.

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PMC9429973

Aims: The dynamics of CAR-T quantity and subtypes in PBS were evaluated, and correlated with responsiveness to treatment and treatment-related toxicities.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ...

PMC11269933

Specifically, the phosphorylation level of Ser11 in C. angulata was significantly upregulated (p < 0.05, 2.8-fold), while it showed a slight increase in C. gigas (1.63-fold).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11742231

IMIPMF demonstrates high performance with a reliable AUC value, highlighting its effectiveness despite only considering known miRNA-disease associations and miRNA expression data.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "IMIPMF"...

PMC11487720

The L929S cell stable transfectant, expressing EGFP-TRAF2(124–233), strongly resisted UV/cold shock-induced BCD.

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PMC9429973

According to the bioinformatics analysis, FGF/FGFR3 was the most significant signaling pathway for PMBCL in our study, because it is able to activate all listed pathways via FGFR-receptor activation.

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PMC10808409