PMCID string | Sentences string | ner list |
|---|---|---|
PMC11750165 | Our observations imply that a critical role of PEX1 in the cell-fate decision of proliferating neural precursors in the p3 domain during the continuing growth and development of the vertebrate nervous system. | [
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PMC11650848 | We deemed it most appropriate to use cell line pairs that had only one factor different between them, namely the presence of absence of DNA methylation. | [
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PMC11216402 | We identified TFs driving the mesenchymal (RUNX2, ZEB1, SNAI2, AP-1 dimer) and the epithelial (GATA4, GATA6, KLF5, HNF4A, FOXA2, GRHL2) states in GC. | [
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PMC11607764 | Consequently, PTBP1 has emerged as a promising candidate for tumor diagnosis, molecular subtyping, and prognosis assessment. | [
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PMC11536589 | The protein levels of MGST1 in AsPC1-MR cells transfected with different RNA interference (RNAi) molecules. | [
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PMC11661040 | GSK3 agonist: 30µM DIF-3) (*P < 0.05, **P < 0.01, ***P < 0.001) Inhibition of wnt pathway could reverse the effect of CGREF1 overexpression on osteosarcoma cells. ( | [
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PMC11400680 | As we are focusing on instance segmentation, our prompt generator (YOLOv9) detects each instance (individual cell or nucleus) and returns the corresponding bounding box prompt for each instance. | [
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PMC11089031 | The most enriched pathways were adaptive immune response, regulation of cytokine production, and T and B cell activation (Figure S1B, orange bars). | [
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PMC9964654 | The results obtained (Figure 5) showed a steady and controlled release of the gold complexes from the micelles. | [
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PMC9429973 | Circulating tumor DNA analysis of MRD at mo 3 and 6 was predictive of relapse (AUC 0.80 and 0.75, respectively). | [
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PMC9429973 | Methods: The primary objective was the comparison of Chronic Graft-versus-Host Disease-free and Relapse-free survival (cGRFS) from time of randomization. | [
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PMC11707832 | Similarly, developing small molecule drugs targeting MAN2B1 might face functional interference and side effects on MAN2A1. | [
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PMC9429973 | Eight of them underwent allogeneic hematopoietic stem cell transplant had head and neck SCC, esophageal cancer, breast cancer, and papillary thyroid cancer. | [
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PMC11093197 | Immunoblotting of total c‐Myc, phospho‐c‐Myc (Serine 62), and phospho‐c‐Myc (threonine 58) proteins. ( | [
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PMC11155445 | Compound (161g) was also a potent insecticidal agent with LC50 values of 0.0068 mM and 0.0085 mM against C. quinquefasciatus and A. stephensi (Fig. 87). | [
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PMC9429973 | Aims: The efficacy and safety of bosutinib in resistant and intolerant patients with CML treated with 2 (3L) and 3 (4L) prior TKIs was characterized. | [
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PMC10719213 | Prior to variant calling, we perform realignment for insertions and deletions (indels) based on indels in the input reads with minimum of three indel containing reads. | [
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PMC2191929 | Analysis of the cytotoxic activity of individual transfectant clones showed that cytolytic and nucleolytic activity correlated with granzyme expression but was independent of cytolysin expression within the range examined. | [
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PMC11763533 | Considering that, herein we also analyzed the possibility of using Amy-Luc as a temperature sensor. | [
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PMC9429973 | Table 1 and 2 summarizes the results from the univariate and multivariate analysis for 2 years OS and PFS, respectively. | [
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PMC11718109 | Live calcium imaging of DA neurons (day 50) (H) shows massive spike in calcium levels after high KCL stimulation (H’). | [
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PMC11794847 | Enrichment analysis revealed that differentially expressed genes were primarily associated with mitochondrial components and oxidative phosphorylation metabolic pathways (Fig. 5A–B). | [
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PMC5443223 | Following two washes with washing buffer (0.5% Tween in PBS), the membranes were incubated with horseradish peroxidase-conjugated secondary anti-rabbit antibody (1:3,000; ab6721; Abcam) for 1 h at room temperature. | [
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PMC11585587 | And RA induces apoptosis in MM cells by arresting the cell cycle, inducing the change of MMP, triggering the mitochondrial apoptosis pathway, and regulating the MAPK/ERK cascade signaling. | [
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PMC11473843 | The last treatment with the inhibitors was performed 2–3 h before lung harvesting. | [
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PMC11650848 | We highlighted that this region contains a CTCF site, but further investigation is needed to fully elucidate its complete function. | [
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PMC11240052 | p13 NCBI). | [
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PMC10154881 | Viral titers were determined as the TCID50 using the Reed–Muench method and Vero/N4 cells for rMV‐SLAMblind and rMV‐EGFP‐SLAMblind, as described previously. | [
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PMC4485648 | Accordingly, sulforaphane treatment leads to diminished pH regulation and reduced migration of ovarian carcinoma cells. | [
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PMC9693627 | It was assumed previously that PTCD2 is involved in the maturation of the mitochondrial pre-mRNA of apocytochrome b and ND5 . | [
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PMC11547972 | Amygdalin (5 mg/mL) slightly elevated G0/G1 phase A498 cells and lowered the number of A498 and KTCTL-26 cells in the S-phase. | [
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PMC3888431 | The redundant transcripts of both pipeline results were removed by aligning the reference-based transcripts to the non-reference-based transcripts. | [
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PMC11678130 | The A375 and HaCaT cells were each treated with different concentrations of QUE (5, 10, 25, or 50 µM), 5-FU (5, 10, 25, or 50 µM), and QUE (10 µM) + 5-FU (5, 10, 25, or 50 µM) for 24 h. The 5-FU stock solution was prepared in ultrapure distilled water, while the QUE stock solution was prepared in DMSO. | [
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PMC7348793 | It was originally developed for the propagation of pure populations of recombinant SV40 viruses; however, its uses also includes the propagation of polyomavirus and rotavirus , as well as research on ion channels , apoptosis and autophagy , immunology , cell biology , vitamin , hormone and cell signaling . | [
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PMC9429973 | It is reported that paeoniflorin has great potential in neuroprotection, which can reduce neuronal damage by reducing the secretion of IL6 and other inflammasomes. | [
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PMC11587541 | Spinal Muscular Atrophy (SMA) primarily results from the biallelic deletion of SMN1 exon 7, accounting for the majority of cases. | [
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PMC9429973 | Comorbidity rates did not differ between Group-1 and Group-2, with the exception of hypertension and chronic kidney disease, which were less frequently reported in Group-1 (P=0.0092 and P=0.0179, respectively). | [
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PMC9429973 | RNAseq analyses showed that PIK3IP1 is dramatically upregulated(Fig.1D). | [
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PMC10411253 | He had bilateral cryptorchidism and received an orchidopexy at 6 years of age. | [
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PMC11576293 | For C21H22N2O2SCl (M + H) 401.10850; found 401.10739. | [
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PMC11684821 | CD161 defines a transcriptional and functional phenotype across distinct human T cell lineages (43). | [
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PMC4005030 | The mechanism of the chemopreventive action of protocatechuic acid is mostly associated with antioxidant activity, including inhibition of generation as well as scavenging of free radicals and upregulating antioxidant enzymes. | [
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PMC11697703 | miR-193b and miR-365 gain-of-function decreases dendritic complexity in superficial-layer neurons (A) Experimental approach for miRs loss-of-function (LoF) and gain-of-function (GoF) in deep-layer neuron cultures. ( | [
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PMC9429973 | Secondary endpoints include number of pts bridging to SCT, progression-free survival, overall survival, best overall response, duration of response, TAG dose interruptions/administration of IV albumin supplementation in pts with CLS or CLS symptoms, as well as safety and incidence and severity of adverse events of special interest (which include CLS and hepatic, renal, and cardiac events). | [
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"O",
"O",
... |
PMC9429973 | Those testing positive for BCR-ABL1 were excluded. | [
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PMC9532503 | The resulting nucleotide sequences of both LC and HC were synthetized together with the signal sequences. | [
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PMC9429973 | Secreted by all types of cells, exosomes are nano-scaled particles which carry a molecular cargo that reflects their cell of origin. | [
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PMC11367939 | C Co-expression of ATG9A-EGFP and synaptophysin (untagged) in COS7 cells. | [
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PMC11655498 | Applications of the NLP techniques bear high potential in the assistance of unveiling new targets for EBV reactivation. | [
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PMC11589157 | Total RNA was extracted using a RNeasy Mini Kit (Qiagen 74104, Qiagen, Germany). | [
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PMC10726501 | Invasionassay was applied to detect the invasive capacities of GIST882 cells. ( | [
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PMC10213179 | After washing with PBS, cell pellets were lysed directly using a cytoplasmatic extraction buffer (10 mM HEPES [pH 7.6], 60 mM KCl, 1 mM EDTA, 0.075% [v/v] NP40, 1 mM DTT, and protease/phosphatase inhibitors) and vortexed. | [
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PMC9429973 | Statistical analysis of medians between cohorts were compared by the non-parametric Mann-Whitney (Graphpad Prism). | [
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PMC10900886 | Representative gating strategies for flow cytometry analyses. ( | [
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PMC11711871 | G, H Representative Western blot analyses of G adrenal (GR, n = 6; GR, n = 6) and H aortic rat sEH protein abundance (r sEH, 64kD, GR, n = 5; GR, n = 4) on a NSD (upper panel) or HSD (lower panel) and their quantification (left panels, NSD; right panels, HSD). | [
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PMC11655498 | Furthermore, advancements in various new technologies can provide valuable insights into the critical mechanisms underlying EBV reactivation from multiple perspectives. | [
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... |
PMC5839394 | R1 and R2 corresponded to the Rayleigh scattering peaks. | [
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PMC9429973 | Image: Summary/Conclusion: Substantial and clinically relevant improvements in QoL were consistently observed with PEG across both EORTC QLQ-C30, total LASA and FACIT-Fatigue scores and clinically significant improvements in fatigue and dyspnea are highly relevant to the symptomology of PNH. | [
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PMC9429973 | Pts received 3 cycles of Ibr, followed by 12 cycles of I+V (Ibr 420 mg/d orally; Ven ramp-up to 400 mg/d orally). | [
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PMC10452486 | Carreno and Hansen confidently claim that the binding of exogenous peptide ligand can influence the expression and half-life of B2m-free HLA variants at the cell surface. | [
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PMC11269933 | This study discovered that phosphorylation of the conserved PK Ser11 site in mollusks (Bivalvia and Gastropoda) significantly enhances its enzyme activity. | [
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PMC11653552 | To this aim, miR-590-3p was found to be released at elevated levels in the culture medium of MM cell lines panel compared to the levels from a lymphoblastoid cell line (LCL). | [
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... |
PMC11629192 | The CD19 B cells was measured in percentage. | [
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PMC11746942 | In this study, we found that S1PR3 expression was closely related to the severity of psoriasis. | [
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"O",
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PMC11674441 | Most breast cancers are detected at an early stage, and the risk of recurrence can be reduced through surgery and drug therapy to prevent recurrence, but there are still many cases of recurrence . | [
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PMC5673060 | Blue coloured proteins are from the cluster list and grey are added STRING interactors. | [
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PMC2196094 | To obtain the complete sequences of these proteases, the ∼500-bp insert fragments were used as probes in screenings of the RBL-1 cDNA library. | [
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... |
PMC11323699 | Fig. 6TAX2 efficacy in a metastatic mouse model of ovarian cancer. | [
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PMC11754784 | CEM, K562, Ramos and PMI-8826 cells were used as the model cancer cells. | [
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PMC11767725 | Elevated androgens, such as testosterone and dihydrotestosterone, stimulate sebaceous gland hypertrophy and sebum overproduction. | [
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"O",
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PMC10745221 | The methionine addiction of cancer cells is known as the Hoffman effect. | [
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PMC4277423 | The resulting vector was designated as pRRL-Cas9-HA-NLS. | [
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PMC11752740 | Fig. 9The effects of pistachio hull extract (E), carfilzomib (CFZ), and their combination on Caspase3 gene expression levels in SK-BR3 and MCF10A cell lines. | [
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"tags": [
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... |
PMC11588085 | We examined the stemness composition of OVCAR3-KRAB cells with XIST KD using mRNA SC-derived embryoid bodies index (EB-index), which reflects the transcriptomic signature of embryonic bodies made of pluripotent SCs, mesoderm, endoderm, and ectoderm progenitor cells (52). | [
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PMC11453018 | E RT-qPCR analysis of senolytics target gene expression following 24 and 72 hours of iP300w (1µM) treatment. | [
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"tags": [
"O",
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PMC11394227 | In CHO-PAb and CHO-PAb-QS cells, antibody folding efficiency, ER stress markers, ER and Golgi apparatus contents, anti-death ability, and redox status were measured and evaluated to reveal the mechanism of HsQSOX1b and survivin co-expression affecting the production efficiency of CHO cells. | [
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PMC9000591 | Accordingly, oxidative stress can exacerbate the inflammatory process, which mediates most chronic diseases, including cancer. | [
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"O",
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"O",
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PMC11656048 | EdU proliferation assays indicated that shikonin inhibits the proliferation of MG63 and 143B (Figures 1G, I) in a dose-dependent manner. | [
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"O",
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... |
PMC9429973 | M. Sciumè, A. Bosi, G. Ceparano, C. De Magistris, F. Serpenti, P. De Roberto, G. Galassi, F. Onida, N. S. Fracchiolla Hematology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy; Università degli Studi di Milano, Milan, Italy Background: Combination of venetoclax and hypomethylating agents (HMAs) has become a standard of care in adult patients with acute myeloid leukemia (AML) who are aged≥75 years or who have comorbidities that preclude use of intensive induction chemotherapy. | [
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"tags": [
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PMC10243817 | Oral glucocorticoid and intranasal steroid sprays were discontinued at least 3 months and 1 month before surgery, respectively. | [
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PMC11750161 | The cAMP homogeneous time-resolved fluorescence (HTRF) assay kit was purchased from Cisbio (Codolet, France). | [
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"tags": [
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PMC9429973 | Accordingly, patients with submono-nucleosomal cluster had a lower PFS. | [
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PMC11672142 | C NMR data are reported by chemical shift (ppm). | [
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PMC10196713 | SOD activities were monitored by using SOD Assay Kit-WST (Dojindo Laboratories, Inc.), according to the manufacturer's instructions. | [
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"tokens": [
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PMC11366496 | Based on univariate and multivariate Cox regression analyses, RNF122 mRNA expression level was correlated to WHO stage; hence, it was found to be an independent predictor of unfavorable survival outcomes in glioma patients (Table S2), indicating that RNF122 might be a potential glioma biomarker. | [
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"tags": [
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PMC11544122 | 2SNX9 binding to the carboxy-terminal tail of CXCR4.a–d SNX9 binding to the carboxyl-terminal tail (CT) of CXCR4 was assessed by GST pulldown. | [
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"tags": [
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PMC9583612 | In addition, GHGSat conducted satellite measurements concurrently at the enrolled assets when weather conditions allowed. | [
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PMC11750712 | Few studies to date have reported on use of CAR T in PTCL. | [
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PMC10605143 | In particular, the MYC oncogene could be responsible for higher levels of HSF1 expression in tumors (according to the Human Protein Atlas, the expression levels of both genes in tumors correlate well with each other). | [
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"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11798926 | How might SynDIG1’s localization and trafficking impact synapse development and plasticity? | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"How",
"might",
"SynDIG1",
"’s",
"localization",
"and",
"trafficking",
"impact",
... |
PMC11281366 | HIV-1 is protected from CML via the incorporation of several complement-regulatory proteins, such as CD46, CD55 and CD59, into viral particles . | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
... |
PMC11357960 | The following fluorescently-conjugated antibodies were used for cell phenotypic analysis: CD45- PerCP (BD Bioscience, USA; Cat#652803), CD3-FITC (BD Bioscience, USA; Cat#349201), CD4-APC-Cy7 (BD Bioscience, USA; Cat#557871), CD8-PE-Cy7 (BD Bioscience, USA; Cat#557746), CD19-APC (BD Bioscience, USA; Cat#652804), CD56- BV510 (BD Bioscience, USA; Cat#563041), CD69-Alexa Fluor 700 (BD Bioscience, USA; Cat#560739). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11286266 | Lower panel: Grey rectangles in top panels indicate the subcellular polyclonal population re-sorted to analyse single ATF6αΔ clones in parental and CRTΔ clones. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
... |
PMC11225860 | The accumulation of stagnant and apoptotic cells in G2 will fail to progress through mitosis and into G1, resulting in declining G1 populations. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
... |
PMC8097906 | Based on our previous anti-cancer studies in breast and bone cancer, we performed an anti-tumor screening with the focus on the anti-metastatic properties of two selected medicinal plant extracts: Vincetoxicum arnottianum Wight and Linum usitatissimum and four plant-derived compounds: genistein, daidzein, matairesinol and secoisolariciresinol on the pediatric RMA cell line RH-30 [21–23]. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC10197932 | AS shown in Figure 5.2 B, a small decrease in cytosolic Calcein-AM uptake was observed and most Calcein was retained in the viable lymphocytes (89.13% of Untreated (UT) cells, about 58.55% for treated (T) cells, and 54.33% for cells 2T). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11767817 | 5637 cells, at a density of 15 × 10, were seeded in a 96-well plate and incubated overnight. | [
{
"tags": [
"B-CellLine",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"5637",
"cells",
","... |
PMC11569208 | Multi-step and single-step growth curves of 786-0 infected with VSV∆51-NTC or VSV∆51-shACP2 (MOI 0.01 or 1). | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"Multi-step",
"and",
"single-... |
PMC8193813 | The boiler stacks are about 20m apart and reach over 20m in height above ground level. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"The",
"boiler",
"stacks",
"are",
"abou... |
PMC11683240 | B–C, PT (10 ng/ml) and different concentrations of α1AT or the respective amount of solvent (H2O) were added directly to CHO-K1 cells in FCS-free medium and incubated for 4 h at 37 °C. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
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