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PMC11777207
All patients provided written and informed consent and the study was approved by the institutional review board at the University of Colorado-Anschutz.
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PMC11144200
For the goal of evaluating whether LPS-RGD-Nb36-DOX may increase effector T-cell growth, specific categories of effector T cells had been pre-marked by 7-AAD as well as then co-cultivated with DC/Hep3B fusion cells or DC/A-427 fusion cells at a 10:1 ratio for 5 days.
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PMC11739696
Despite its rarity, this type of skin cancer accounts for the majority of skin cancer deaths.
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PMC11786704
The results showed that at pH 7.4 and 5.5, the release rate and amount of PC were slow.
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PMC8658661
Thus, it has been shown that CYP3A4, which is one of the key enzymes of drug cleavage , is 100–400 times less in HepG2 cells than in hepatocytes .
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PMC6835428
Among the different novel drugs, small interfering RNAs (siRNAs) are particularly attractive because of their specificity of action and efficacy, as documented in many experimental setups.
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PMC9429973
EPB42 (band 4.2)) may be sufficient to characterize most of the patients.
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PMC8073654
This compound also suppressed the in vitro invasion and migration of MDA-MB-231 cells and in vivo metastasis in a breast cancer mouse model (a luciferase-expressing metastatic human breast cancer cell (MDA-MB-231-Luc-D3H2LN) implanted in nonobese diabetic/severe combined immune-deficient (NOD/SCID) mice).
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PMC11754432
Primary pooled adult normal human epidermal keratinocytes (Promocell, Heidelberg, Germany) and NHEK/SVTERT3-5 (Evercyte, Vienna, Austria) were cultured in keratinocyte growth media 2 (Promocell) containing supplementMix (Promocell) and 50 µg/ml G418 (InvivoGen, Toulouse, France) termed KGM2.
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PMC10565698
Alpha-fetoprotein (AFP) is a well-known and extensively used clinical diagnostic biomarker for primary LC .
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PMC9164404
We found here that Abplatin might induce the change of BEL-7404 cell membrane, hence resulting in the disorder of glycerophospholipids and sphingolipids.
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PMC11703992
Notably, NF-κB and MAPK pathways were significantly enriched in protein pathways.
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PMC11779605
RNA quality and concentration were determined using the Eukaryote Total RNA Pico Series II assay run on the Bioanalyzer 2100 (Agilent Technologies, Santa Clara, CA, USA).
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PMC10538569
Briefly, at various indicated time intervals post co-culture between HIV-1-captured iDCs or mDCs and pRRL-GPI-scFv X5 or AB65-2A-GFP-transduced human primary CD4 T cells, small portion of cell mixture was harvested, washed with 1 ml FACS buffer, fixed and permeabilized by Cytofix/Cytoperm kit (Becton Dickinson).
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PMC11544771
Furthermore, we noticed that in response to the combined treatment, the percent cells in the sub-G1 phase were also significantly increased, suggesting that the number of apoptotic cells increased (Figure 4B).
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PMC11106977
Researchers have partially elucidated the mechanisms through which O-GlcNAcylation affects the activity of Runx2.
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PMC10482220
Therefore, it was important to know whether p21 would play a role in SG assembly and/or recruitment of G3BP to SGs.
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PMC6684588
The gastrocnemius muscle received unilateral injections of ACE-083 or vehicle (phosphate-buffered saline, PBS) twice weekly for 4 weeks. (
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PMC11190538
The elevated pH level of the C-phycocyanin-enriched yoghurt might be attributable to the C-phycocyanin pH (6.55), which demonstrates that C-phycocyanin has a significant impact.
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PMC9429973
Our nomogram provides a visual depiction of the relative contribution of each prognostic factor to the total point score and, thus, the weight of factors regarding probability for VTE development (Picture 1).
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PMC7039683
There are only five elements in the genome where all of these features converge, and each score in the top 2% bin or higher (Figure 4—figure supplement 2).
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PMC11697703
In this way, the miR-193b∼365 cluster may contribute to the distinct development of dendritic fields of these neuron subtypes.
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PMC10976516
The stroma is a multi-componential tissue, which consists of tumor-associated macrophages (TAMs), the (compact) extracellular matrix, tumor vasculature, and, to a large degree, cancer-associated fibroblasts (CAFs), which all together as non-epithelial, tumor-associated stromal cells (TACs) create a proficient tumor environment.
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PMC11127909
C qPCR examination of the mRNA levels of EFHD1 in OS cell lines, N = 3.
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PMC9118379
We further propose an examination of OMS combined with explosive search, i.e., using the three OMS tools (MSFragger, PIPI, and SpecOMS) to search against the SuperPep_V database to examine the reliability of variant PSMs.
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PMC11767725
The overproduction of sebum provides a nutrient-rich substrate for C. acnes, promoting its colonization and metabolic activity.
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PMC11244823
Interestingly, only three gG1-positive individuals stratified among the vaccinated animals in the gD1_83-positive group.
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PMC10047551
We conclude that there is a regulatory link between PD-L1 DNA methylation and expression.
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PMC11721277
However, for diagnostic purposes, a lower dose of these agents can be employed compared to their therapeutic use.
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PMC6627640
All downstream analysis presented in Figures and Tables included the biological triplicates of each cell line.
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PMC7039683
Embryos injected were examined by epifluorescence microscopy first at approximately 11 hpf, then each day subsequently until approximately four dpf.
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PMC9429973
However, very little data is available regarding the risk of secondary myeloid neoplasm (MNs) in pts with IBD except for the well-known association between azathioprine with therapy related MNs.
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PMC9954564
NanoDrop ND-1000 (Thermo Fisher Scientific Inc., Waltham, MA, USA), agarose gel electrophoresis, and Qubit™ dsDNA BR Assay (Life Technologies, Carlsbad, CA, USA) were used for the evaluation of purity level, integrity, and concentration of the genomic DNA, respectively.
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PMC11766174
Overall, this improvement offers a clear advantage of using CA-ICC over flow cytometry for the detection of the translationally active reservoir.
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PMC11683240
α1AT, α1-antitrypsin; PT, pertussis toxin.
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PMC11721587
Here, we show that signal-induced formation of kinase condensates to allosterically activate pathway transcription factors represents a unified mechanism for Hh signal transduction from Drosophila to mammals despite their differential requirement for primary cilia.
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PMC5311252
To further validate the results from the LUAD analysis, the breast cancer dataset (BRCA) was selected because it showed a generally high correlation between oncomotif-miRNAs and TS targets.
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PMC5839394
The same pattern was detected in exposed cells to IC50 of AgNPs-EPS for 24 h (data not shown).
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PMC10553757
A. Fry: None.
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PMC11782508
The growth profile and azurin production of P. aeruginosa strain 105 were investigated.
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PMC11748335
UTR, untranslated region; TSS, transcription start site; TTS, transcription termination site.
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PMC11770130
Carbamidomethylation on cysteine was set as a fixed modification, and acetylation on the protein N-terminus and oxidation of methionine were set as variable modifications.
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PMC11803210
Top 5 pathways from downregulated genes.
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PMC11726183
The molecular ion peaks in the HRMS spectra were represented as [M + H], and they perfectly matched the molecular weight of the synthesized molecules.
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PMC9429973
Consistently, histopathological analyses of th3 mice showed dysmegakaryopoiesis and this defect was confirmed in BM sections from BT patients.
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PMC9429973
Mean (SD) change from baseline to TAT in Hb level was 2.6 (1.8) and 2.7 (1.8) g/dL for patients with versus without prior rituximab use, respectively.
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PMC11126803
∗∗p < 0.01, ∗∗∗ p < 0.001, ns = not significant.
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PMC9429973
An attempt to target inflammatory vasculopathy and to modulate inflammatory response has been made based on evidence in other diseases such as in cardiovascular disease looking to administration of ω-3 fatty acids.
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PMC6461034
Centrifuge at 2,000 × g for 30 s at 4°C to pellet the beads.
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PMC9429973
In a randomized clinical trial, CPX-351 has shown superior overall survival (OS) compared to standard anthracycline-cytarabine schedule in these AML subtypes.
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PMC11474209
No.Cell-lineDose of MC-LRProtein/factorSignaling pathway involvedRepercussionToxicity/Phenotypic effects to be addressReferences1HL−77020.01–1 μMBLK, cGAScGAS-STING signaling pathwayCause an immune-mediated response and mutationHepatic disease2Human gastric cancer cell line (SGC−9701)0–10 μMKrt16 and ERαEstrogen signaling pathwayProliferation, invasion, migration, anti-apoptosis activityGastric cancer3Human uroepithelial cells (SV-HUC−1)1–1000 nMCyclin D1PI3K/AKT/GSK3β/ mTOR/HIF−1α/VEGFCyclin D1 and JAK2/STAT3/Bcl2 signaling pathwaysProliferation of urinary bladder, SV-HUC−1 cell angiogenesisBladder cancer4Human aortic vascular smooth muscle cell line (HAoSMC)0.01–1 μMCaspase−3 and caspase−9Integrin β1, Rho, ROCK, MLC, and integrin-mediated FAK/ROCK signaling pathwayROS generation, MMP loss, cytoskeleton impairment, S-phase arrest, and cell deathHinder the migration and proliferating of HAVSMCs5RWPE−1 cells (epithelial cell-derived cell line)10–500 nMMMP−2, MMP−9FOXM1/COX2Triggering of malignant phenotype in human prostate epithelial cellsProstate Cancer6Human hepatic stellate cell line (LX−2)500 nMα-SMA, collagen I, Gli1/2HedgehogProliferation, fibrosis, prevent cell viabilityHepatic fibrosis7HL−77021 μM, 5 μM and 10 μMIRS1, Akt, GSK−3, GS, PP2A and INS signaling proteinInsulin signaling pathway,Affect the phosphorylation levels of proteinsToxic effect hepatic glucose metabolism8HepaRG10, 100 and 1000 ng mLNrf−2, CHOP, NOXA, JUN and FOS, NF-κβ,PP1, PP2, UPR, p53, DR5, GADD34, ATF3, MAPk/p38Morphological changes, raised ROS and oxidative stress, accumulation of in outpace of ERDamage to liver9Human hepatoma cell line (HepG2 and SMMC−7721)0–10 µMPP2A/MAPK/p53, cdc25C, and cdc2MAPK/PP2A pathwayMigration, invasion and HepG2 proliferationHepatocellular carcinoma (HCC)10HepG21 µg/mLPP1A and PP2A-Oxidative stress and damage to DNACytotoxicity and genotoxic11HL77020–10 µMFoxOFoxO, KEGG, PI3K-AKT, MAPK, Ras signaling pathway, cell cycleAffect the hepatic circRNAs, toxicity to liver, ER stressLiver damage12Human normal intestinal epithelium cells (NCM460)5 or 10 μMp-p53PP2ADNA damage, elevated ROS levelGenotoxicity13Human neuroblastoma cell line (SK-N-SH)15 or 30 μmol/Lp62 and LC3 II/LC3 I-Cell viability, accumulation of autophagosomes, increased concentration of free intracellular calciumNeuronal toxicity14Human normal liver cell line (LO2)10 μg/Lp53, Bax, CTNNB1 and MMP7Wnt/β-catenin and p53 signaling pathwaysProgrammed cell death.
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"O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No.", "Cell-lineDose", "of", "MC-LRProtein/factorSignaling", "pathway", "involvedRepercussionToxicity/Phenotypic", "effects", "to", "be", "addressReferences1HL−77020.01–1", "μMBLK", ",", "cGAScGAS-STING", "signaling", "pathwayCause", "an", "immune-mediated", "response", "and", "mutationHepatic", "disease2Human", "gastric", "cancer", "cell", "line", "(SGC−9701)0–10", "μMKrt16", "and", "ERαEstrogen", "signaling", "pathwayProliferation", ",", "invasion", ",", "migration", ",", "anti-apoptosis", "activityGastric", "cancer3Human", "uroepithelial", "cells", "(SV-HUC−1)1–1000", "nMCyclin", "D1PI3K/AKT/GSK3β/", "mTOR/HIF−1α/VEGFCyclin", "D1", "and", "JAK2/STAT3/Bcl2", "signaling", "pathwaysProliferation", "of", "urinary", "bladder", ",", "SV-HUC−1", "cell", "angiogenesisBladder", "cancer4Human", "aortic", "vascular", "smooth", "muscle", "cell", "line", "(HAoSMC)0.01–1", "μMCaspase−3", "and", "caspase−9Integrin", "β1", ",", "Rho", ",", "ROCK", ",", "MLC", ",", "and", "integrin-mediated", "FAK/ROCK", "signaling", "pathwayROS", "generation", ",", "MMP", "loss", ",", "cytoskeleton", "impairment", ",", "S-phase", "arrest", ",", "and", "cell", "deathHinder", "the", "migration", "and", "proliferating", "of", "HAVSMCs5RWPE−1", "cells", "(", "epithelial", "cell-derived", "cell", "line)10–500", "nMMMP−2", ",", "MMP−9FOXM1/COX2Triggering", "of", "malignant", "phenotype", "in", "human", "prostate", "epithelial", "cellsProstate", "Cancer6Human", "hepatic", "stellate", "cell", "line", "(LX−2)500", "nMα-SMA", ",", "collagen", "I", ",", "Gli1/2HedgehogProliferation", ",", "fibrosis", ",", "prevent", "cell", "viabilityHepatic", "fibrosis7HL−77021", "μM", ",", "5", "μM", "and", "10", "μMIRS1", ",", "Akt", ",", "GSK−3", ",", "GS", ",", "PP2A", "and", "INS", "signaling", "proteinInsulin", "signaling", "pathway", ",", "Affect", "the", "phosphorylation", "levels", "of", "proteinsToxic", "effect", "hepatic", "glucose", "metabolism8HepaRG10", ",", "100", "and", "1000", "ng", "mLNrf−2", ",", "CHOP", ",", "NOXA", ",", "JUN", "and", "FOS", ",", "NF-κβ", ",", "PP1", ",", "PP2", ",", "UPR", ",", "p53", ",", "DR5", ",", "GADD34", ",", "ATF3", ",", "MAPk/p38Morphological", "changes", ",", "raised", "ROS", "and", "oxidative", "stress", ",", "accumulation", "of", "in", "outpace", "of", "ERDamage", "to", "liver9Human", "hepatoma", "cell", "line", "(", "HepG2", "and", "SMMC−7721)0–10", "µMPP2A/MAPK/p53", ",", "cdc25C", ",", "and", "cdc2MAPK/PP2A", "pathwayMigration", ",", "invasion", "and", "HepG2", "proliferationHepatocellular", "carcinoma", "(HCC)10HepG21", "µg/mLPP1A", "and", "PP2A-Oxidative", "stress", "and", "damage", "to", "DNACytotoxicity", "and", "genotoxic11HL77020–10", "µMFoxOFoxO", ",", "KEGG", ",", "PI3K-AKT", ",", "MAPK", ",", "Ras", "signaling", "pathway", ",", "cell", "cycleAffect", "the", "hepatic", "circRNAs", ",", "toxicity", "to", "liver", ",", "ER", "stressLiver", "damage12Human", "normal", "intestinal", "epithelium", "cells", "(NCM460)5", "or", "10", "μMp-p53PP2ADNA", "damage", ",", "elevated", "ROS", "levelGenotoxicity13Human", "neuroblastoma", "cell", "line", "(SK-N-SH)15", "or", "30", "μmol/Lp62", "and", "LC3", "II/LC3", "I-Cell", "viability", ",", "accumulation", "of", "autophagosomes", ",", "increased", "concentration", "of", "free", "intracellular", "calciumNeuronal", "toxicity14Human", "normal", "liver", "cell", "line", "(LO2)10", "μg/Lp53", ",", "Bax", ",", "CTNNB1", "and", "MMP7Wnt/β-catenin", "and", "p53", "signaling", "pathwaysProgrammed", "cell", "death", "." ] } ]
PMC11653533
Some phytochemicals such as β amyrins, stigmasterol, campesterol, ϒ sitosterol, oleic acid, isoamyl laurate, α and ϒ tocopherols in dried fruits of F. carica, however various studies have been reported that these phytochemicals have various biological potency, for example, β amyrins has very significant glycyrrhizin potency; stigmasterol has the potency to manufacture semi-synthetic progesterone hormone, as well as, potency to prevent certain kind of cancers, including ovarian, prostate, breast and colon cancers, it also act as an antioxidant, hypoglycemic and thyroid inhibitor; campesterol convey anti-inflammatory activity; ϒ sitosterol has antimicrobial and antioxidant activities, as well as, potency to reduce saturated fat and cholesterol, thus, may reduce the risk of heart diseases; oleic acid act as emollient; isoamyl laurate has the potency to conditioning hair; α tocopherols has antioxidant potency, which leads to slowing aging; ϒ tocopherols has inflammation and anticancer potency (Soni et al., 2014).
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PMC9143157
The tumor weight of the P-THP treatment group at 36 days after treatment was significantly lower than both the control (p < 0.001) and THP treatment group (p < 0.002), whereas no significant decrease of tumor weight was found in the THP treatment group compared to the control group (Figure 3C,D).
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PMC9429973
TALEN® gene editing technology was used to mediate inactivation of the TRAC and CD52 genes: TRAC KO is used to prevent Graft-vs-Host Disease, and CD52 KO to allow deeper host lymphocyte depletion by conferring resistance to lymphodepletion regimens including an anti-CD52 monoclonal antibody, such as alemtuzumab.
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PMC11424574
siRNA-ERK was designed and synthesized by GenePharma (Shanghai, China).
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PMC11703992
The concentric circles sequentially from the center represent weighted mode, weighted median, simple mode, MR-Egger and IVW.
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PMC10877303
Despite this, numerous therapeutics have been demonstrated in preclinical studies, and several of them have undergone clinical testing .
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PMC11551844
The sample was loaded on the column using the dry loading method.
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PMC10840195
For the Transwell invasion assays, 1 × 10 cells/mL of cells were cultured in the Transwell chamber with extracellular matrix gel (Sigma, E1270), which was diluted on ice with serum-free medium at a ratio of 1:8.
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PMC9000591
Moreover, the Callerya genus is well acknowledged for its pharmaceutical properties due to the existence of numerous valuable secondary compounds such as alkaloids, triterpenoids, coumarins, flavonoids, isoflavonoids, phenols, and phytosterols .
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PMC9024365
Our results demonstrate the effects of SD4 on clustering both GluA1 and GluA2 in heterologous cells.
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PMC9621239
Cell cycles were analysed using flow cytometry of Huh 7 cells.
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PMC11594074
Among the multitude of effects methylation has on cancer development, the hypermethylation of gene promoters, such as tumor suppressor genes, plays an important role in the carcinogenesis of liver cancer, breast cancer, and many other tumor types.
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PMC11719944
On the other hand, in CD8+ T cells, there was a statistically significant decrease in the central memory cell compartment in patients with T1D compared to the group of healthy individuals (20.87 ± 8.414 vs. 12.68 ± 11.88 cells/μL) (Figure 6b).
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PMC6627640
The cisplatin adduct assay was based on the protocol of Han et al. .
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PMC9895440
Statistics are unpaired t-tests.
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PMC10898159
THZ1 blocks the role of CDK7 on RNAPII, and thus decrease the transcriptions of odd-skipped related transcription factor 1(OSR1), which is one of super enhancer (SE) of KIT gene in GIST .
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PMC11306019
However, we opted not to use these compounds for extended treatment experiments, given that these polyphenols are known to have low bioavailability or could undergo extensive metabolism in the body (Luca et al., 2020; Alizadeh and Ebrahimzadeh, 2022).
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PMC11599565
Then, another glass capillary (VacuTip II) was used to release trypsin–EDTA solution within the vicinity of the cell of interest.
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PMC11286266
The ATF6α–CRT interaction is cartooned here as having both glycan (Gly)-dependent and -independent components.
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PMC11347429
The library was sequenced on Illumina HiSeq 4000 using the HiSeq 3000/4000 SBS Kit (300 cycles).
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PMC10253553
Anti-NDRG1 (#5196S), anti-phospho-NDRG1 (Thr346) (#5482), anti-β-actin (#4970), anti-Rictor (#2114), anti-S6 (#2217), anti-phospho-S6 (235/236) (#4858), anti-PARP (#9532), and anti-cleaved PARP (#5625) were purchased from Cell Signaling Technology (Danvers, MA, USA)).
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PMC10006224
Cohesin mediates sister chromatid cohesion and organizes the genome through the formation of chromatin loops.
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PMC10079526
U2OS cells were cultured in suspension and treated for 4 or 20 h with 1 µM 5-Aza-2’ or DMSO 0.1% control with or without MG132 10 µM for 4 h and 2.5 µM for 20 h. Total lysate input and His10-SUMO2- pulldown elutions were analyzed by immunoblotting using SMC6 antibody.
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PMC10729469
Guide RNAs (gRNAs) encoding the α- and β- chains of the TCR were electroporated into polyclonal Tregs isolated from non-transgenic mice (Fig. 1A).
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PMC11040965
We also found that the exogenous addition of miR29b to transfected U266 and RPMI 8226 cells reduces PI3K/AKT pathway activity, implying that a regulatory loop exists between miR29b and the PI3K/AKT pathway in which they mutually control each other.
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PMC11760643
Following incubation, 50 µL from all wells were transferred to corresponding wells of a new flat‐bottom 96‐well plate.
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PMC8708099
These changes might have been caused by stressful conditions, such as the addition of exogenous substances to the culture medium, especially that histamine is a well-known agent stimulating colorectal cell line proliferation, including Caco-2 .
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PMC9919300
We revealed that the cytotoxicity of the steatosis treatment was reverted by andrographolide, suggesting its potential protective effect alone (76.3% vs. 62.2%, p < 0.01) and in association (75.8% vs. 62.2%, p < 0.05) (Figure 2).
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PMC11271278
A HiChIP and ChIP-seq signal at chromosomal regions containing ETV1 and the hijacked enhancers in MDAPCA2B and LNCaP cells.
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PMC11621493
Murine Pla2g4d was identified, together with Pla2g4e and Pla2g4f, by performing homology searches using Pla2g4a and Pla2g4c exons as query sequences (31).
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PMC11672617
Annexin V (5 μL) and 7-AAD (1 μL) solutions were subsequently added to the reaction mixture and incubated for 15 min at room temperature in the dark.
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PMC8270637
The mice were sacrificed 14 days after transplantation.
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PMC9545474
She then worked with Profs P. J. Sadler FRS and N. P. E. Barry on the applications of metallated compounds at the University of Warwick and the University of Bradford before taking up an assistant professorship at Bradford.. She was appointed as tenured CNRS Researcher (chargée de recherche) at Institut Galien Paris‐Saclay (Université Paris‐Saclay, France) in 2021.
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PMC9429973
However, the best agent to prevent thrombotic events without increasing the bleeding incidence among these patients remains uncertain.
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PMC9429973
A common feature with all of the patients was relatively mild thrombocytopenia, and possibly an underlying predisposition for thrombosis.
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PMC11621565
The images are representative of two independent experiments, each performed in duplicate wells (n = 4).
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PMC11469524
In many disease contexts, these pathways are deregulated, for instance by mutations in key signaling proteins.
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PMC11258145
The results obtained for these models confirmed that curcumin had a significantly greater effect on the membrane parameters of neuroblastoma cells (SK-N-SH) with these effects observed even at the lipid:curcumin ratio of 64:1, while for promyelocytic cells (HL-60) only at the ratio 8:1.
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PMC11224020
To assess the physiological relevance of shape sensing by ARP2/3 and cPLA2, we evaluated whether cPLA2, WASp and Arpin deficiencies altered the number of migratory DCs present in skin-draining lymph nodes at steady state by flow cytometry.
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PMC11024707
Mi-RNA-125b-5p was originally identified as a tumor suppressor.
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PMC8973085
Prompted by these and as an extension of our preceding effort in the chemistry of pyridine, pyridinethione, and thienopyridine, we describe here the synthesis of a new series of substituted and condensed pyridines.
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PMC10818062
The underlying mechanism remains unclear.
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PMC10810426
This suggested that MLV reverse transcription occurred in both compartments of infected DCs.
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PMC9429973
Methods: We established a 19-color full spectrum flow cytometry panel with one tube containing CD45, CD34, CD117, CD13, CD33, HLA-DR, CD2, CD4, CD5, CD7, CD11b, CD14, CD15, CD19, CD22, CD38, CD56, CD64 and CD133.
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PMC9325715
The occurred changes can be explained by the utilized conditions, i.e. the reaction mixture comprised not only bLTF and Fe but also a small amount of citrate ions (the iron ammonium citrate salt was utilized as a source of Fe).
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PMC10840195
Representative WB results for sunitinib-treated A498 and SR-A498 cells (A).
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PMC9878562
We have previously shown that GC derived DLBCL VAL cells, require the functional expression of ACKR3 to disseminate into distant organs in NOD/SCID mice (32).
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PMC10222971
In contrast, the cytotoxic properties of derivative 3 (5-acetoxy-1,4-naphthoquinone) have been previously reported in the literature.
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PMC11750161
The Multalin multiple sequence alignment tool was used for the sequence analysis.
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