OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC11746942	The data are presented as the mean ± SD. ****	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "data", "are", "presented", "as", "the", "mean", "±", "SD", ".", "", "", "", "" ] } ]
PMC11453018	Fig. 7The restoration of LMNB1 and P15 expression in iP300w-treated cells delays senescence and induces apoptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "7The", "restoration", "of", "LMNB1", "and", "P15", "expression", "in", "iP300w-treated", "cells", "delays", "senescence", "and", "induces", "apoptosis", "." ] } ]
PMC11066331	Acetonitrile (ACN) was purchased from Penta (Prague, Czech Republic).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Acetonitrile", "(", "ACN", ")", "was", "purchased", "from", "Penta", "(", "Prague", ",", "Czech", "Republic", ")", "." ] } ]
PMC9429973	Furthermore, after microenvironmental stimulation, DUSP levels increased in CLL lymph nodes compared to peripheral blood (DUSP1: log2-fold change of 2.6, p=0.0094; DUSP6: log2-fold change of 1.8, p=2.2*10e-7; Herishanu et al, 2011) and stromal coculture.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "after", "microenvironmental", "stimulation", ",", "DUSP", "levels", "increased", "in", "CLL", "lymph", "nodes", "compared", "to", "peripheral", "blood", "(", "DUSP1", ":", "log2-fold", "change", "of", "2.6", ",", "p=0.0094", ";", "DUSP6", ":", "log2-fold", "change", "of", "1.8", ",", "p=2.2", "*", "10e-7", ";", "Herishanu", "et", "al", ",", "2011", ")", "and", "stromal", "coculture", "." ] } ]
PMC11612626	Also, we did not detect an effect of the compound A–treated cells on appetite, gait, skin turgor, or musculoskeletal or neurologic systems (Supplementary Fig. S7D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Also", ",", "we", "did", "not", "detect", "an", "effect", "of", "the", "compound", "A", "–", "treated", "cells", "on", "appetite", ",", "gait", ",", "skin", "turgor", ",", "or", "musculoskeletal", "or", "neurologic", "systems", "(", "Supplementary", "Fig.", "S7D", ")", "." ] } ]
PMC7582629	To improve the Raman sensing of breast cancer cells differentiation, the normalized average Raman spectra of those cell lines were examined and compared.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "improve", "the", "Raman", "sensing", "of", "breast", "cancer", "cells", "differentiation", ",", "the", "normalized", "average", "Raman", "spectra", "of", "those", "cell", "lines", "were", "examined", "and", "compared", "." ] } ]
PMC11172027	We will carry out further studies to confirm that other mechanisms may also be involved in the effects that NALM and NaSeLM exhibit.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "will", "carry", "out", "further", "studies", "to", "confirm", "that", "other", "mechanisms", "may", "also", "be", "involved", "in", "the", "effects", "that", "NALM", "and", "NaSeLM", "exhibit", "." ] } ]
PMC11725127	G, H) USP2 knockout MM.1S and RPMI 8226 cells were treated with 50 μg/mL CHX for the indicated time points.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "G", ",", "H", ")", "USP2", "knockout", "MM.1S", "and", "RPMI", "8226", "cells", "were", "treated", "with", "50", "μg/mL", "CHX", "for", "the", "indicated", "time", "points", "." ] } ]
PMC11536589	MGST1 production has been found to inhibit ferroptosis by suppressing lipid peroxidation, although it does not impede iron accumulation in PDAC cells (Kuang et al. 2021).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MGST1", "production", "has", "been", "found", "to", "inhibit", "ferroptosis", "by", "suppressing", "lipid", "peroxidation", ",", "although", "it", "does", "not", "impede", "iron", "accumulation", "in", "PDAC", "cells", "(", "Kuang", "et", "al.", "2021", ")", "." ] } ]
PMC11335267	As a negative control, note the absence of Alx3 immunoreactivity in COS cells transfected with empty vector. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "a", "negative", "control", ",", "note", "the", "absence", "of", "Alx3", "immunoreactivity", "in", "COS", "cells", "transfected", "with", "empty", "vector", ".", "(" ] } ]
PMC9622879	Hence, in time slot t, the day-ahead selling price can be determined as with .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hence", ",", "in", "time", "slot", "t", ",", "the", "day-ahead", "selling", "price", "can", "be", "determined", "as", "with", "." ] } ]
PMC9874064	CLSM imags of DNA damage related protein γ-H2AX expression (blue, DAPI; Green, γ-H2AX).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CLSM", "imags", "of", "DNA", "damage", "related", "protein", "γ-H2AX", "expression", "(", "blue", ",", "DAPI", ";", "Green", ",", "γ-H2AX", ")", "." ] } ]
PMC10759659	In the CHCC-HBV cohort, patients were selected as hepatitis B core antibody (HBcAb) and hepatitis B surface antigen (HBsAg) positive.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "CHCC-HBV", "cohort", ",", "patients", "were", "selected", "as", "hepatitis", "B", "core", "antibody", "(", "HBcAb", ")", "and", "hepatitis", "B", "surface", "antigen", "(", "HBsAg", ")", "positive", "." ] } ]
PMC11467964	Although STS accounts for approximately 1% of adult malignancies, its incidence is relatively higher among adolescents.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Although", "STS", "accounts", "for", "approximately", "1", "%", "of", "adult", "malignancies", ",", "its", "incidence", "is", "relatively", "higher", "among", "adolescents", "." ] } ]
PMC11591052	These activities include anabolic, adaptogenic, hypoglycemic, antioxidant, cardioprotective, hepatoprotective, and neuroprotective effects on healthy tissues .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "activities", "include", "anabolic", ",", "adaptogenic", ",", "hypoglycemic", ",", "antioxidant", ",", "cardioprotective", ",", "hepatoprotective", ",", "and", "neuroprotective", "effects", "on", "healthy", "tissues", "." ] } ]
PMC10698968	All cell lines were cultured in DMEM high glucose supplemented with 10% lot-selected FBS, 1% L-glutamine, and 1% Penicillin/Streptomycin (all from Life Technologies).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "cell", "lines", "were", "cultured", "in", "DMEM", "high", "glucose", "supplemented", "with", "10", "%", "lot-selected", "FBS", ",", "1", "%", "L-glutamine", ",", "and", "1", "%", "Penicillin/Streptomycin", "(", "all", "from", "Life", "Technologies", ")", "." ] } ]
PMC5261804	Patients without the JAK1-PIK3R1 PPI have improved survival compared to patients who retain this PPI.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "without", "the", "JAK1-PIK3R1", "PPI", "have", "improved", "survival", "compared", "to", "patients", "who", "retain", "this", "PPI", "." ] } ]
PMC9429973	We aim to investigate the efficacy and safety of MCBC conditioning regimen for allo-HSCT in R/R AML patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "aim", "to", "investigate", "the", "efficacy", "and", "safety", "of", "MCBC", "conditioning", "regimen", "for", "allo-HSCT", "in", "R/R", "AML", "patients", "." ] } ]
PMC11359735	All data pertinent to this work are contained within this article and are available upon request from M. A. J. F. and P. S. This article contains supporting information (26).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "data", "pertinent", "to", "this", "work", "are", "contained", "within", "this", "article", "and", "are", "available", "upon", "request", "from", "M.", "A.", "J.", "F.", "and", "P.", "S.", "This", "article", "contains", "supporting", "information", "(", "26", ")", "." ] } ]
PMC11352311	The wound areas at both time points were measured using the Image J 1.54 software, and the wound closure rates were calculated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "wound", "areas", "at", "both", "time", "points", "were", "measured", "using", "the", "Image", "J", "1.54", "software", ",", "and", "the", "wound", "closure", "rates", "were", "calculated", "." ] } ]
PMC9429973	IgG levels against SARS-CoV-2 spike protein were analyzed with Abbott SARS-CoV-2 IgG II Quant-test with ≥50 AU/ml as a threshold for positivity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "IgG", "levels", "against", "SARS-CoV-2", "spike", "protein", "were", "analyzed", "with", "Abbott", "SARS-CoV-2", "IgG", "II", "Quant-test", "with", "≥50", "AU/ml", "as", "a", "threshold", "for", "positivity", "." ] } ]
PMC11703992	The probability of cell–cell interactions was inferred subsequently.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "probability", "of", "cell", "–", "cell", "interactions", "was", "inferred", "subsequently", "." ] } ]
PMC11607638	The pancreas was excised, and rat pancreatic acini were isolated by collagenase P (0.2 g L, 10 mL) digestion in a shaking water bath (37°C, 110 cycles per min).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "pancreas", "was", "excised", ",", "and", "rat", "pancreatic", "acini", "were", "isolated", "by", "collagenase", "P", "(", "0.2", "g", "L", ",", "10", "mL", ")", "digestion", "in", "a", "shaking", "water", "bath", "(", "37", "°", "C", ",", "110", "cycles", "per", "min", ")", "." ] } ]
PMC10421378	For intestinal barrier formation, Caco-2 cells were seeded on the PET membranes (Millicell Cell Culture Inserts, 24 mm diameter, 0.4 µm pore size) (Millipore, Burlington, MA, USA, Merck Group) at an initial density of 4 × 10 cells/cm and cultured for 21 days with a medium change three times a week.	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "intestinal", "barrier", "formation", ",", "Caco-2", "cells", "were", "seeded", "on", "the", "PET", "membranes", "(", "Millicell", "Cell", "Culture", "Inserts", ",", "24", "mm", "diameter", ",", "0.4", "µm", "pore", "size", ")", "(", "Millipore", ",", "Burlington", ",", "MA", ",", "USA", ",", "Merck", "Group", ")", "at", "an", "initial", "density", "of", "4", "×", "10", "cells/cm", "and", "cultured", "for", "21", "days", "with", "a", "medium", "change", "three", "times", "a", "week", "." ] } ]
PMC11604768	Surprisingly, inhibitor treatment did not significantly alter the activation of THRB-1 promoters, despite these being associated with the 5-HT2A projection (Fig. 5a−d, Supplementary Fig. 9F).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Surprisingly", ",", "inhibitor", "treatment", "did", "not", "significantly", "alter", "the", "activation", "of", "THRB-1", "promoters", ",", "despite", "these", "being", "associated", "with", "the", "5-HT2A", "projection", "(", "Fig.", "5a−d", ",", "Supplementary", "Fig.", "9F", ")", "." ] } ]
PMC10454535	The Pierce BCA Protein Assay Kit (Thermo Fisher Scientific Inc.) was used to quantify protein samples, which were loaded at 20 μg per well into a 10 well 4–20% Mini-PROTEAN TGX precast gel (Bio-Rad Laboratories, Hercules, CA, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "Pierce", "BCA", "Protein", "Assay", "Kit", "(", "Thermo", "Fisher", "Scientific", "Inc.", ")", "was", "used", "to", "quantify", "protein", "samples", ",", "which", "were", "loaded", "at", "20", "μg", "per", "well", "into", "a", "10", "well", "4–20", "%", "Mini-PROTEAN", "TGX", "precast", "gel", "(", "Bio-Rad", "Laboratories", ",", "Hercules", ",", "CA", ",", "USA", ")", "." ] } ]
PMC11190062	Heatmap showing correlation between TLR genes and chromosomal abnormalities in MMRF CoMMpass dataset IA14.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Heatmap", "showing", "correlation", "between", "TLR", "genes", "and", "chromosomal", "abnormalities", "in", "MMRF", "CoMMpass", "dataset", "IA14", "." ] } ]
PMC7039683	Workflow of ATAC-seq in epithelium and mesenchyme cells isolated from palate shelves dissected from E14.5 embryos. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Workflow", "of", "ATAC-seq", "in", "epithelium", "and", "mesenchyme", "cells", "isolated", "from", "palate", "shelves", "dissected", "from", "E14.5", "embryos", ".", "(" ] } ]
PMC11319300	This was taken alongside CTCF data, Supplementary Table S3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "was", "taken", "alongside", "CTCF", "data", ",", "Supplementary", "Table", "S3", "." ] } ]
PMC9429973	We performed adoptive transfer (AT) of TCL1 derived CLL cells into Ebi3 and WT mice, as well as generated the transgenic mouse model Eµ-TCL1-Ebi3.The splenic TME of these mice was characterized using flow cytometry.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "performed", "adoptive", "transfer", "(", "AT", ")", "of", "TCL1", "derived", "CLL", "cells", "into", "Ebi3", "and", "WT", "mice", ",", "as", "well", "as", "generated", "the", "transgenic", "mouse", "model", "Eµ-TCL1-Ebi3.The", "splenic", "TME", "of", "these", "mice", "was", "characterized", "using", "flow", "cytometry", "." ] } ]
PMC4695073	The cases eligibility criteria were as follows: histologically proven and newly diagnosed NPC without treatment history; locally advanced and no distant metastasis; no serious complications or other primary tumors; treated with chemoradiotherapy containing platinum-based regimens (at least 2 chemotherapy cycles) and regularly followed up in Sun Yat-sen University Cancer Center .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cases", "eligibility", "criteria", "were", "as", "follows", ":", "histologically", "proven", "and", "newly", "diagnosed", "NPC", "without", "treatment", "history", ";", "locally", "advanced", "and", "no", "distant", "metastasis", ";", "no", "serious", "complications", "or", "other", "primary", "tumors", ";", "treated", "with", "chemoradiotherapy", "containing", "platinum-based", "regimens", "(", "at", "least", "2", "chemotherapy", "cycles", ")", "and", "regularly", "followed", "up", "in", "Sun", "Yat-sen", "University", "Cancer", "Center", "." ] } ]
PMC9429973	Median time to first response was 7 days (range 6–114), and to VGPR or better 54 days (range 6–219).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Median", "time", "to", "first", "response", "was", "7", "days", "(", "range", "6–114", ")", ",", "and", "to", "VGPR", "or", "better", "54", "days", "(", "range", "6–219", ")", "." ] } ]
PMC11040965	Beyond these limitations, with this paper, we describe a novel pathogenetic mechanism that completes the immunological picture, sketched in our previous reports , of what occurs in the bone marrow during MM development.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Beyond", "these", "limitations", ",", "with", "this", "paper", ",", "we", "describe", "a", "novel", "pathogenetic", "mechanism", "that", "completes", "the", "immunological", "picture", ",", "sketched", "in", "our", "previous", "reports", ",", "of", "what", "occurs", "in", "the", "bone", "marrow", "during", "MM", "development", "." ] } ]
PMC11592837	With mean values close to 1.0, drug-treated Jurkat cells exhibited similar MTCO3 fragment ratios until 2 h; afterward, they reached a plateau (1.61) with ETP and 1.41 with DOX, albeit without statistical significance to the control levels (Figure 7C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "With", "mean", "values", "close", "to", "1.0", ",", "drug-treated", "Jurkat", "cells", "exhibited", "similar", "MTCO3", "fragment", "ratios", "until", "2", "h", ";", "afterward", ",", "they", "reached", "a", "plateau", "(", "1.61", ")", "with", "ETP", "and", "1.41", "with", "DOX", ",", "albeit", "without", "statistical", "significance", "to", "the", "control", "levels", "(", "Figure", "7C", ")", "." ] } ]
PMC9429973	The 3-year cumulative incidence of NRM was 20%.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "3-year", "cumulative", "incidence", "of", "NRM", "was", "20", "%", "." ] } ]
PMC11155445	Second, via cyclization with α-bromoacetophenone in the presence of trimethylamine under sonication give thiazole-2-imine (18).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Second", ",", "via", "cyclization", "with", "α-bromoacetophenone", "in", "the", "presence", "of", "trimethylamine", "under", "sonication", "give", "thiazole-2-imine", "(", "18", ")", "." ] } ]
PMC11407042	Take the vial containing A549 cells from the nitrogen tank and thaw the A549 cells at 37°C in a water bath immediately.	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Take", "the", "vial", "containing", "A549", "cells", "from", "the", "nitrogen", "tank", "and", "thaw", "the", "A549", "cells", "at", "37", "°", "C", "in", "a", "water", "bath", "immediately", "." ] } ]
PMC11188874	A P-value ≤ 0.05 is flagged with one star () and a P-value ≤ 0.001 is flagged with three stars (**).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "P-value", "≤", "0.05", "is", "flagged", "with", "one", "star", "(", "", ")", "and", "a", "P-value", "≤", "0.001", "is", "flagged", "with", "three", "stars", "(", "", "", "", ")", "." ] } ]
PMC11092382	However, these findings are currently limited to cell-based experimental models, thus, confirmation of the independent anti-HBV activity of sophocarpine in in vivo is still lacking.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "these", "findings", "are", "currently", "limited", "to", "cell-based", "experimental", "models", ",", "thus", ",", "confirmation", "of", "the", "independent", "anti-HBV", "activity", "of", "sophocarpine", "in", "in", "vivo", "is", "still", "lacking", "." ] } ]
PMC11670407	l Representative IHC images of GPX4 and quantitative analysis of GPX4-positive cells (n = 6) (scale bars: 200 μm and 400 μm).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "l", "Representative", "IHC", "images", "of", "GPX4", "and", "quantitative", "analysis", "of", "GPX4-positive", "cells", "(", "n", "=", "6", ")", "(", "scale", "bars", ":", "200", "μm", "and", "400", "μm", ")", "." ] } ]
PMC10798140	It was also the most effective chemical against cell migration and adhesion, which could play an important role in drug resistance and cell metastasis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "was", "also", "the", "most", "effective", "chemical", "against", "cell", "migration", "and", "adhesion", ",", "which", "could", "play", "an", "important", "role", "in", "drug", "resistance", "and", "cell", "metastasis", "." ] } ]
PMC11593031	Based on patient age, tumor extent, lymph node infiltration or distant metastasis, and the extent of initial surgical tumor resection, NBs are classified into stages according to the International Neuroblastoma Staging System (INSS).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Based", "on", "patient", "age", ",", "tumor", "extent", ",", "lymph", "node", "infiltration", "or", "distant", "metastasis", ",", "and", "the", "extent", "of", "initial", "surgical", "tumor", "resection", ",", "NBs", "are", "classified", "into", "stages", "according", "to", "the", "International", "Neuroblastoma", "Staging", "System", "(", "INSS", ")", "." ] } ]
PMC5417661	It should, however, be noted that OvCar-4 cells treated with a higher 50 nM concentration of NOV202 underwent a massive cell death; at 24, 48 and 72 h time points the average CDI was 28.7%±6.8%, 48.3%±10.7% and 59.3%±13.2%, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "should", ",", "however", ",", "be", "noted", "that", "OvCar-4", "cells", "treated", "with", "a", "higher", "50", "nM", "concentration", "of", "NOV202", "underwent", "a", "massive", "cell", "death", ";", "at", "24", ",", "48", "and", "72", "h", "time", "points", "the", "average", "CDI", "was", "28.7%±6.8", "%", ",", "48.3%±10.7", "%", "and", "59.3%±13.2", "%", ",", "respectively", "." ] } ]
PMC8728081	The suspended Kajjali and Rasasindura particles were exposed to the adherent NIH3T3 cell line at various concentrations from 10 to 1000 ppm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "suspended", "Kajjali", "and", "Rasasindura", "particles", "were", "exposed", "to", "the", "adherent", "NIH3T3", "cell", "line", "at", "various", "concentrations", "from", "10", "to", "1000", "ppm", "." ] } ]
PMC11371747	Cells originating from the CaCo-2 and WiDr cell lines were adapted to grow in RPMI-1640 LF medium supplemented with 2.5 nM l-LV as a representative for a more physiological environment (Backus et al., 2000; Lemos et al., 2008).	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "originating", "from", "the", "CaCo-2", "and", "WiDr", "cell", "lines", "were", "adapted", "to", "grow", "in", "RPMI-1640", "LF", "medium", "supplemented", "with", "2.5", "nM", "l-LV", "as", "a", "representative", "for", "a", "more", "physiological", "environment", "(", "Backus", "et", "al.", ",", "2000", ";", "Lemos", "et", "al.", ",", "2008", ")", "." ] } ]
PMC11764090	Preventing ice crystal formation is regarded as a crucial mechanism of cold tolerance in plants.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Preventing", "ice", "crystal", "formation", "is", "regarded", "as", "a", "crucial", "mechanism", "of", "cold", "tolerance", "in", "plants", "." ] } ]
PMC9318744	Cell-free virus supernatant was harvested 72 h post-infection when < 70% cytopathic effects were evident.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell-free", "virus", "supernatant", "was", "harvested", "72", "h", "post-infection", "when", "<", "70", "%", "cytopathic", "effects", "were", "evident", "." ] } ]
PMC10523483	Cell survival of tBHP-treated H1.2 knockout A549 cells and the control group with/without GCLC overexpression, n = 5 per group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "survival", "of", "tBHP-treated", "H1.2", "knockout", "A549", "cells", "and", "the", "control", "group", "with/without", "GCLC", "overexpression", ",", "n", "=", "5", "per", "group", "." ] } ]
PMC11286266	The screen identified both anticipated and new candidate genes that regulate ATF6α activation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "screen", "identified", "both", "anticipated", "and", "new", "candidate", "genes", "that", "regulate", "ATF6α", "activation", "." ] } ]
PMC11727000	BRCA2 is a tumor suppressor best known for mutations associated with hereditary breast and ovarian cancer, but mutations are also associated with predisposition to other cancers including childhood leukemia and neuroblastoma .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "BRCA2", "is", "a", "tumor", "suppressor", "best", "known", "for", "mutations", "associated", "with", "hereditary", "breast", "and", "ovarian", "cancer", ",", "but", "mutations", "are", "also", "associated", "with", "predisposition", "to", "other", "cancers", "including", "childhood", "leukemia", "and", "neuroblastoma", "." ] } ]
PMC4695073	Briefly, total RNA was extracted using TRIzol reagent.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Briefly", ",", "total", "RNA", "was", "extracted", "using", "TRIzol", "reagent", "." ] } ]
PMC9429973	Image: Summary/Conclusion: SARS-CoV-2 vaccination in SAA may result in transient decline in blood counts but true relapse is rare.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Image", ":", "Summary/Conclusion", ":", "SARS-CoV-2", "vaccination", "in", "SAA", "may", "result", "in", "transient", "decline", "in", "blood", "counts", "but", "true", "relapse", "is", "rare", "." ] } ]
PMC9429973	Image: Summary/Conclusion: Our data show similar high efficacy of KRd and KTd in elderly NTE NDMM pts, including no difference in ORR (KRd and KTd, 87.3% and 95%, respectively), PFS and OS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Image", ":", "Summary/Conclusion", ":", "Our", "data", "show", "similar", "high", "efficacy", "of", "KRd", "and", "KTd", "in", "elderly", "NTE", "NDMM", "pts", ",", "including", "no", "difference", "in", "ORR", "(", "KRd", "and", "KTd", ",", "87.3", "%", "and", "95", "%", ",", "respectively", ")", ",", "PFS", "and", "OS", "." ] } ]
PMC10079526	Subsequently, foci were counted within the Macro.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Subsequently", ",", "foci", "were", "counted", "within", "the", "Macro", "." ] } ]
PMC9429973	Humoral non-response was defined as the absence of a humoral response.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Humoral", "non-response", "was", "defined", "as", "the", "absence", "of", "a", "humoral", "response", "." ] } ]
PMC11367146	p < 0.05 between untreated and IL1β-induced group; p < 0.05 and *p < 0.01 between IL-1β and VTE treated group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "p", "<", "0.05", "between", "untreated", "and", "IL1β-induced", "group", ";", "", "p", "<", "0.05", "and", "", "*", "p", "<", "0.01", "between", "IL-1β", "and", "VTE", "treated", "group", "." ] } ]
PMC11763111	C Flowchart shows that mice (n = 5) were injected intravenously with 3 × 10 CCRF-CEM-Luc-GFP cells, followed by 2.5 × 10 CAR-T/PCDH-T cells five days later.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "C", "Flowchart", "shows", "that", "mice", "(", "n", "=", "5", ")", "were", "injected", "intravenously", "with", "3", "×", "10", "CCRF-CEM-Luc-GFP", "cells", ",", "followed", "by", "2.5", "×", "10", "CAR-T/PCDH-T", "cells", "five", "days", "later", "." ] } ]
PMC11472569	EVs can protect miRNAs from degradation by RNases, unlike naked miRNAs, opening new avenues for overcoming MDR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "EVs", "can", "protect", "miRNAs", "from", "degradation", "by", "RNases", ",", "unlike", "naked", "miRNAs", ",", "opening", "new", "avenues", "for", "overcoming", "MDR", "." ] } ]
PMC9429973	The CALR mutated patients were younger in age but the median platelet counts, WBC count and Hemoglobin were not statistically different among different mutation groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "CALR", "mutated", "patients", "were", "younger", "in", "age", "but", "the", "median", "platelet", "counts", ",", "WBC", "count", "and", "Hemoglobin", "were", "not", "statistically", "different", "among", "different", "mutation", "groups", "." ] } ]
PMC7759933	The visual analysis of HepG2 spheroids by confocal microscopy verified the time-resolved viability of the cells in a 3D culture, which was more or less stable over the cultivation time.	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "visual", "analysis", "of", "HepG2", "spheroids", "by", "confocal", "microscopy", "verified", "the", "time-resolved", "viability", "of", "the", "cells", "in", "a", "3D", "culture", ",", "which", "was", "more", "or", "less", "stable", "over", "the", "cultivation", "time", "." ] } ]
PMC11612794	The images in the figures are the maximum intensity projection of the Z-stack generated with Fiji.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "images", "in", "the", "figures", "are", "the", "maximum", "intensity", "projection", "of", "the", "Z-stack", "generated", "with", "Fiji", "." ] } ]
PMC11509224	Diterpene alkaloids were also found from an Okinawan marine sponge (Agelas sp.) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Diterpene", "alkaloids", "were", "also", "found", "from", "an", "Okinawan", "marine", "sponge", "(", "Agelas", "sp.", ")", "." ] } ]
PMC7841189	In summary, the present study has provided further evidence that knockdown of LTBP2 inhibits invasion and tumorigenesis in thyroid carcinoma cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "summary", ",", "the", "present", "study", "has", "provided", "further", "evidence", "that", "knockdown", "of", "LTBP2", "inhibits", "invasion", "and", "tumorigenesis", "in", "thyroid", "carcinoma", "cells", "." ] } ]
PMC7868205	However, genotoxic effects were observed at 0.01–10 mg/mL in BEAS-2B, a normal lung epithelial cell line.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "genotoxic", "effects", "were", "observed", "at", "0.01–10", "mg/mL", "in", "BEAS-2B", ",", "a", "normal", "lung", "epithelial", "cell", "line", "." ] } ]
PMC11637716	Although SBDS mutations are responsible for about 90% of cases, we now know that genetic alterations leading to SDS or SDS‐like phenotypes may also be caused by pathogenic variants in DNAJC21, SRP54 and EFL1. , , , ,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Although", "SBDS", "mutations", "are", "responsible", "for", "about", "90", "%", "of", "cases", ",", "we", "now", "know", "that", "genetic", "alterations", "leading", "to", "SDS", "or", "SDS‐like", "phenotypes", "may", "also", "be", "caused", "by", "pathogenic", "variants", "in", "DNAJC21", ",", "SRP54", "and", "EFL1", ".", ",", ",", ",", "," ] } ]
PMC11790971	Data analytics and machine learning (ML) techniques have become crucial for understanding the complex relationships between cell profiles and the production phenotypes of CHO cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "Data", "analytics", "and", "machine", "learning", "(", "ML", ")", "techniques", "have", "become", "crucial", "for", "understanding", "the", "complex", "relationships", "between", "cell", "profiles", "and", "the", "production", "phenotypes", "of", "CHO", "cell", "lines", "." ] } ]
PMC10993311	The three DMGMs can be seen in Figure 3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "three", "DMGMs", "can", "be", "seen", "in", "Figure", "3", "." ] } ]
PMC8632470	However, various secondary metabolites, e.g., flavonoids, chalcones, coumarins, phenolics, acetylenes, and terpenes, have been identified in different parts of A. keiskei .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "various", "secondary", "metabolites", ",", "e.g.", ",", "flavonoids", ",", "chalcones", ",", "coumarins", ",", "phenolics", ",", "acetylenes", ",", "and", "terpenes", ",", "have", "been", "identified", "in", "different", "parts", "of", "A.", "keiskei", "." ] } ]
PMC9268620	In summary, the majority of caspase substrates that have been identified are involved in cell regulation, DNA repair, homeostasis, and cell survival.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "summary", ",", "the", "majority", "of", "caspase", "substrates", "that", "have", "been", "identified", "are", "involved", "in", "cell", "regulation", ",", "DNA", "repair", ",", "homeostasis", ",", "and", "cell", "survival", "." ] } ]
PMC9429973	CRS occurred in 68% of patients, was primarily associated with the initial doses, and was mostly Grade (Gr) 1 (51%) or Gr 2 (12%); Gr 3 (3%) and Gr 4 (2%) events were uncommon.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CRS", "occurred", "in", "68", "%", "of", "patients", ",", "was", "primarily", "associated", "with", "the", "initial", "doses", ",", "and", "was", "mostly", "Grade", "(", "Gr", ")", "1", "(", "51", "%", ")", "or", "Gr", "2", "(", "12", "%", ")", ";", "Gr", "3", "(", "3", "%", ")", "and", "Gr", "4", "(", "2", "%", ")", "events", "were", "uncommon", "." ] } ]
PMC10605143	In the following days, the medium was replaced with one containing DTHIB at a concentration ranging from 0 to 200 μM in DMSO (max.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "following", "days", ",", "the", "medium", "was", "replaced", "with", "one", "containing", "DTHIB", "at", "a", "concentration", "ranging", "from", "0", "to", "200", "μM", "in", "DMSO", "(", "max", "." ] } ]
PMC9622879	A mixed integer nonlinear programming (MINLP) model for this scheduling problem was built and solved by using General Algebraic Modeling System (GAMS) software.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "mixed", "integer", "nonlinear", "programming", "(", "MINLP", ")", "model", "for", "this", "scheduling", "problem", "was", "built", "and", "solved", "by", "using", "General", "Algebraic", "Modeling", "System", "(", "GAMS", ")", "software", "." ] } ]
PMC9429973	High transcriptional variability was observed between the PC clusters of the AL patients indicating a high degree of heterogeneity among the AL PCs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "High", "transcriptional", "variability", "was", "observed", "between", "the", "PC", "clusters", "of", "the", "AL", "patients", "indicating", "a", "high", "degree", "of", "heterogeneity", "among", "the", "AL", "PCs", "." ] } ]
PMC10729469	Notably, APP/PS1 mice treated with polyclonal Tregs showed significantly increased frequencies of total Tregs compared to untreated APP/PS1 mice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notably", ",", "APP/PS1", "mice", "treated", "with", "polyclonal", "Tregs", "showed", "significantly", "increased", "frequencies", "of", "total", "Tregs", "compared", "to", "untreated", "APP/PS1", "mice", "." ] } ]
PMC7351993	These results are consistent with the RIACS’s ability to provide molecular-vibrational images of cells in a high-speed flow with a subcellular spatial resolution as shown in Fig. 3a–d. Specifically, Fig. 3a shows intracellular lipids (green) in various types of microalgal cells cultured under nitrogen deficiency conditions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "results", "are", "consistent", "with", "the", "RIACS", "’s", "ability", "to", "provide", "molecular-vibrational", "images", "of", "cells", "in", "a", "high-speed", "flow", "with", "a", "subcellular", "spatial", "resolution", "as", "shown", "in", "Fig.", "3a", "–", "d.", "Specifically", ",", "Fig.", "3a", "shows", "intracellular", "lipids", "(", "green", ")", "in", "various", "types", "of", "microalgal", "cells", "cultured", "under", "nitrogen", "deficiency", "conditions", "." ] } ]
PMC8427838	Immunofluorescence staining with an antibody against K40-acetylated tubulin in 786-0 cells expressing empty vector (EV) or TMIGD1 revealed that the level of K40-acetylated tubulin in 786-0 cells expressing TMIGD1 was significantly higher than observed for the cells expressing EV (Fig. 5A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Immunofluorescence", "staining", "with", "an", "antibody", "against", "K40-acetylated", "tubulin", "in", "786", "-", "0", "cells", "expressing", "empty", "vector", "(", "EV", ")", "or", "TMIGD1", "revealed", "that", "the", "level", "of", "K40-acetylated", "tubulin", "in", "786", "-", "0", "cells", "expressing", "TMIGD1", "was", "significantly", "higher", "than", "observed", "for", "the", "cells", "expressing", "EV", "(", "Fig.", "5A", ")", "." ] } ]
PMC10114490	The metabolic products of coumarin (7-hydroxycoumarin, assay for CYP2A6 activities), bupropion (hydroxybupropion, assay for CYP2B6 activity), diclofenac (4-hydroxydiclofenac, assay for CYP2C9 activity), chlorzoxazone (6-hydroxychlorzoxazone, assay for CYP2E1 activity) and midazolam (1-hydroxymidazolam, assay for CYP3A4 activity) were determined by liquid chromatography–tandem mass spectrometry.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "metabolic", "products", "of", "coumarin", "(", "7-hydroxycoumarin", ",", "assay", "for", "CYP2A6", "activities", ")", ",", "bupropion", "(", "hydroxybupropion", ",", "assay", "for", "CYP2B6", "activity", ")", ",", "diclofenac", "(", "4-hydroxydiclofenac", ",", "assay", "for", "CYP2C9", "activity", ")", ",", "chlorzoxazone", "(", "6-hydroxychlorzoxazone", ",", "assay", "for", "CYP2E1", "activity", ")", "and", "midazolam", "(", "1-hydroxymidazolam", ",", "assay", "for", "CYP3A4", "activity", ")", "were", "determined", "by", "liquid", "chromatography", "–", "tandem", "mass", "spectrometry", "." ] } ]
PMC10165258	Right: Representation of each condition on a 2D parameter space.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Right", ":", "Representation", "of", "each", "condition", "on", "a", "2D", "parameter", "space", "." ] } ]
PMC11247842	The SNPs which were significant both in the current study and eQTL dataset were retained as potential regulatory variants with effect on udder health.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "SNPs", "which", "were", "significant", "both", "in", "the", "current", "study", "and", "eQTL", "dataset", "were", "retained", "as", "potential", "regulatory", "variants", "with", "effect", "on", "udder", "health", "." ] } ]
PMC6835428	The lacunae are in connection with lymphatic capillaries.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "lacunae", "are", "in", "connection", "with", "lymphatic", "capillaries", "." ] } ]
PMC11173119	Air-dried slides were covered with 7–10 μL antifade (Vector, Newark, CA, USA) under a coverslip.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Air-dried", "slides", "were", "covered", "with", "7–10", "μL", "antifade", "(", "Vector", ",", "Newark", ",", "CA", ",", "USA", ")", "under", "a", "coverslip", "." ] } ]
PMC11258145	The higher the degree of fatty acid saturation, meaning the stiffer the membrane initially, the lower doses of curcumin lead to significant disturbances.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "higher", "the", "degree", "of", "fatty", "acid", "saturation", ",", "meaning", "the", "stiffer", "the", "membrane", "initially", ",", "the", "lower", "doses", "of", "curcumin", "lead", "to", "significant", "disturbances", "." ] } ]
PMC11190538	Table 9Yogurt samplesCFU*10/mlTotal phenolic (GAE mg/g)Total antioxidants (GAE mg/g)C-PC Remain (%)DPPHABTS24 h7 days14 day24 h7 days14 day24 h7 days14 day24 h7 days14 dayAfter 14 daysC3.475.837.32226.00 ± 18.38307.50 ± 6.36271.50 ± 9.1959.51±2.3163.99 ±2.7458.99 ±3.1742.40 ±1.5175.13 ± 1.5771.68 ±0.73–T13.865.948.83685.00 ±19.80775.50±10.61789.50 ±14.8564.69±4.3262.20 ±5.5658.00 ±4.7262.65 ±7.33129.41±3.64123.09±1.7935.77 ± 3.25T23.355.718.24975.50 ±7.78984.50±7.78907.50±10.6164.04±2.3569.01 ±4.5661.17 ±5.2575.37 ±1.33161.12±2.63148.67±15.3639.08 ± 2.85T31.772.684.211132.50±17.681280.00 ±12.731306.50 ±2.1294.36±3.89108.40 ±4.02109.45 ±3.2385.73 ±4.00189.66±2.21198.48±2.3895.25 ± 3.75T41.912.744.461283.50±13.441444.50 ±9.191562.50 ± 9.19104.98 ±3.96127.21 ±5.09128.88 ±3.8289.97 ±4.66203.74 ±4.12201.38±1.2493.45 ± 2.58NB: All yogurt variants were fermented with L. rhamnosus KU985435, C: control without C-PC, T1: treatment with 150 mg free C-PC, T2: treatment with 300 mg free C-PC, T3: treatment with 150 mg C-PC nanophytosomes (at molar ratio 1:2), T4: treatment with 300 mg C-PC nanophytosomes (at molar ratio 1:2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Table", "9Yogurt", "samplesCFU*10/mlTotal", "phenolic", "(", "GAE", "mg/g)Total", "antioxidants", "(", "GAE", "mg/g)C-PC", "Remain", "(%)DPPHABTS24", "h7", "days14", "day24", "h7", "days14", "day24", "h7", "days14", "day24", "h7", "days14", "dayAfter", "14", "daysC3.475.837.32226.00", "±", "18.38307.50", "±", "6.36271.50", "±", "9.1959.51±2.3163.99", "±2.7458.99", "±3.1742.40", "±1.5175.13", "±", "1.5771.68", "±0.73–T13.865.948.83685.00", "±19.80775.50±10.61789.50", "±14.8564.69±4.3262.20", "±5.5658.00", "±4.7262.65", "±7.33129.41±3.64123.09±1.7935.77", "±", "3.25T23.355.718.24975.50", "±7.78984.50±7.78907.50±10.6164.04±2.3569.01", "±4.5661.17", "±5.2575.37", "±1.33161.12±2.63148.67±15.3639.08", "±", "2.85T31.772.684.211132.50±17.681280.00", "±12.731306.50", "±2.1294.36±3.89108.40", "±4.02109.45", "±3.2385.73", "±4.00189.66±2.21198.48±2.3895.25", "±", "3.75T41.912.744.461283.50±13.441444.50", "±9.191562.50", "±", "9.19104.98", "±3.96127.21", "±5.09128.88", "±3.8289.97", "±4.66203.74", "±4.12201.38±1.2493.45", "±", "2.58NB", ":", "All", "yogurt", "variants", "were", "fermented", "with", "L.", "rhamnosus", "KU985435", ",", "C", ":", "control", "without", "C-PC", ",", "T1", ":", "treatment", "with", "150", "mg", "free", "C-PC", ",", "T2", ":", "treatment", "with", "300", "mg", "free", "C-PC", ",", "T3", ":", "treatment", "with", "150", "mg", "C-PC", "nanophytosomes", "(", "at", "molar", "ratio", "1:2", ")", ",", "T4", ":", "treatment", "with", "300", "mg", "C-PC", "nanophytosomes", "(", "at", "molar", "ratio", "1:2", ")", "." ] } ]
PMC11650848	A high-level semantic language task was adapted for this task to compare differences in neural responses to two sentences.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "high-level", "semantic", "language", "task", "was", "adapted", "for", "this", "task", "to", "compare", "differences", "in", "neural", "responses", "to", "two", "sentences", "." ] } ]
PMC9429973	Pts were randomized 1:1, stratified by de novo AML vs. secondary AML, age (60-64 vs 65-70 vs ≥70 yrs), and institution.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Pts", "were", "randomized", "1:1", ",", "stratified", "by", "de", "novo", "AML", "vs.", "secondary", "AML", ",", "age", "(", "60", "-", "64", "vs", "65", "-", "70", "vs", "≥70", "yrs", ")", ",", "and", "institution", "." ] } ]
PMC6742971	Figure 2A shows data of an experiment in which we observed strong specific lysis of Me290 target cells even at the high concentration of a low avidity T cell clone (ratio 8:1 of low:high avidity clones).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Figure", "2A", "shows", "data", "of", "an", "experiment", "in", "which", "we", "observed", "strong", "specific", "lysis", "of", "Me290", "target", "cells", "even", "at", "the", "high", "concentration", "of", "a", "low", "avidity", "T", "cell", "clone", "(", "ratio", "8:1", "of", "low", ":", "high", "avidity", "clones", ")", "." ] } ]
PMC11528603	Further evaluation of the effects of SA-EA at IC50 demonstrated time-independent inhibition on proliferation of HL60 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Further", "evaluation", "of", "the", "effects", "of", "SA-EA", "at", "IC50", "demonstrated", "time-independent", "inhibition", "on", "proliferation", "of", "HL60", "cells", "." ] } ]
PMC11621565	The reaction was terminated at 85°C for 5 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "reaction", "was", "terminated", "at", "85", "°", "C", "for", "5", "min", "." ] } ]
PMC9895440	e Area under the curve (AUC) of Calbryte520-AM Ca flux upon stimulation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "e", "Area", "under", "the", "curve", "(", "AUC", ")", "of", "Calbryte520-AM", "Ca", "flux", "upon", "stimulation", "." ] } ]
PMC11471176	Iman A. Mansi: Resources, Methodology, Investigation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Iman", "A.", "Mansi", ":", "Resources", ",", "Methodology", ",", "Investigation", "." ] } ]
PMC9429973	New potential therapeutic targets (CREBBP, EP300, EZH2, SMARCB1, CD79A/B, BTK, CARD11, MYD88, THFAIP3, PIK3CA, PTEN and JAK) were identified in 55% (11/20) of newly diagnosed patients and in 41.2% (7/17) of relapsed/refractory patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "New", "potential", "therapeutic", "targets", "(", "CREBBP", ",", "EP300", ",", "EZH2", ",", "SMARCB1", ",", "CD79A/B", ",", "BTK", ",", "CARD11", ",", "MYD88", ",", "THFAIP3", ",", "PIK3CA", ",", "PTEN", "and", "JAK", ")", "were", "identified", "in", "55", "%", "(", "11/20", ")", "of", "newly", "diagnosed", "patients", "and", "in", "41.2", "%", "(", "7/17", ")", "of", "relapsed/refractory", "patients", "." ] } ]
PMC10850553	IA lesions (Unruptured aneurysm which never ruptures, Rupture-prone aneurysm or Ruptured aneurysm) or control arterial bifurcations were harvested subjected to immunohistochemical analyses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "IA", "lesions", "(", "Unruptured", "aneurysm", "which", "never", "ruptures", ",", "Rupture-prone", "aneurysm", "or", "Ruptured", "aneurysm", ")", "or", "control", "arterial", "bifurcations", "were", "harvested", "subjected", "to", "immunohistochemical", "analyses", "." ] } ]
PMC10158546	Figure 1.In vitro characteristics of ReN human neural progenitor-derived cultures. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Figure", "1.In", "vitro", "characteristics", "of", "ReN", "human", "neural", "progenitor-derived", "cultures", ".", "(" ] } ]
PMC11670407	In contrast, the results of the wound healing assay demonstrated that compared with the control, OTULIN knockdown alone impeded the migratory capacity of osteosarcoma cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "contrast", ",", "the", "results", "of", "the", "wound", "healing", "assay", "demonstrated", "that", "compared", "with", "the", "control", ",", "OTULIN", "knockdown", "alone", "impeded", "the", "migratory", "capacity", "of", "osteosarcoma", "cells", "." ] } ]
PMC11769516	Fusarium spp.	[ { "tags": [ "O", "O", "O" ], "tokens": [ "Fusarium", "spp", "." ] } ]
PMC11188874	D, Effect of HDAC6 WT, DC, and ΔBUZ mutants on proteasome ChT-like activity in HeLa cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "D", ",", "Effect", "of", "HDAC6", "WT", ",", "DC", ",", "and", "ΔBUZ", "mutants", "on", "proteasome", "ChT-like", "activity", "in", "HeLa", "cells", "." ] } ]
PMC10988555	As the IC50 values in A2780 cells are in the low micromolar range and to ensure ICP-AES sensitivity in terms of limit of detection, the 10× IC50 concentrations were used.	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "the", "IC50", "values", "in", "A2780", "cells", "are", "in", "the", "low", "micromolar", "range", "and", "to", "ensure", "ICP-AES", "sensitivity", "in", "terms", "of", "limit", "of", "detection", ",", "the", "10", "×", "IC50", "concentrations", "were", "used", "." ] } ]
PMC9429973	On the contrary, the decrease in the number of burst-forming cells of erythrocytopoiesis (BFU-E) after 10 months of cryostorage was significantly lower than at earlier periods of cell suspension thawing.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "On", "the", "contrary", ",", "the", "decrease", "in", "the", "number", "of", "burst-forming", "cells", "of", "erythrocytopoiesis", "(", "BFU-E", ")", "after", "10", "months", "of", "cryostorage", "was", "significantly", "lower", "than", "at", "earlier", "periods", "of", "cell", "suspension", "thawing", "." ] } ]
PMC11342785	Higher scores indicate a greater degree of disorder.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Higher", "scores", "indicate", "a", "greater", "degree", "of", "disorder", "." ] } ]
PMC3164356	To augment this gene set, we used CHO-K1 transcriptome data to annotate gene structures with the aid of the programs TopHat and Cufflinks.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "augment", "this", "gene", "set", ",", "we", "used", "CHO-K1", "transcriptome", "data", "to", "annotate", "gene", "structures", "with", "the", "aid", "of", "the", "programs", "TopHat", "and", "Cufflinks", "." ] } ]

PMC11746942

The data are presented as the mean ± SD. ****

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "data", "are", "presented", "as", "the", "mean", "±", "SD", ".", "*", "*", "*", "*" ] } ]

PMC11453018

Fig. 7The restoration of LMNB1 and P15 expression in iP300w-treated cells delays senescence and induces apoptosis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "7The", "restoration", "of", "LMNB1", "and", "P15", "expression", "in", "iP300w-treated", "cells", "delays", "senescence", "and", "induces", "apoptosis", "." ] } ]

PMC11066331

Acetonitrile (ACN) was purchased from Penta (Prague, Czech Republic).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Acetonitrile", "(", "ACN", ")", "was", "purchased", "from", "Penta", "(", "Prague", ",", "Czech", "Republic", ")", "." ] } ]

PMC9429973

Furthermore, after microenvironmental stimulation, DUSP levels increased in CLL lymph nodes compared to peripheral blood (DUSP1: log2-fold change of 2.6, p=0.0094; DUSP6: log2-fold change of 1.8, p=2.2*10e-7; Herishanu et al, 2011) and stromal coculture.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "after", "microenvironmental", "stimulation", ",", "DUSP", "levels", "increased", "in", "CLL", "lymph", "nodes", "compared", "to", "peripheral", "blood", "(", "DUSP1", ":", "log2-fold", "change", "of", "2.6", ",", "p=0.0094", ";", "DUSP6", ":", "log2-fold", "change", "of", "1.8", ",", "p=2.2", "*", "10e-7", ";", "Herishanu", "et", "al", ",", "2011", ")", "and", "stromal", "coculture", "." ] } ]

PMC11612626

Also, we did not detect an effect of the compound A–treated cells on appetite, gait, skin turgor, or musculoskeletal or neurologic systems (Supplementary Fig. S7D).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Also", ",", "we", "did", "not", "detect", "an", "effect", "of", "the", "compound", "A", "–", "treated", "cells", "on", "appetite", ",", "gait", ",", "skin", "turgor", ",", "or", "musculoskeletal", "or", "neurologic", "systems", "(", "Supplementary", "Fig.", "S7D", ")", "." ] } ]

PMC7582629

To improve the Raman sensing of breast cancer cells differentiation, the normalized average Raman spectra of those cell lines were examined and compared.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "improve", "the", "Raman", "sensing", "of", "breast", "cancer", "cells", "differentiation", ",", "the", "normalized", "average", "Raman", "spectra", "of", "those", "cell", "lines", "were", "examined", "and", "compared", "." ] } ]

PMC11172027

We will carry out further studies to confirm that other mechanisms may also be involved in the effects that NALM and NaSeLM exhibit.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "will", "carry", "out", "further", "studies", "to", "confirm", "that", "other", "mechanisms", "may", "also", "be", "involved", "in", "the", "effects", "that", "NALM", "and", "NaSeLM", "exhibit", "." ] } ]

PMC11725127

G, H) USP2 knockout MM.1S and RPMI 8226 cells were treated with 50 μg/mL CHX for the indicated time points.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "G", ",", "H", ")", "USP2", "knockout", "MM.1S", "and", "RPMI", "8226", "cells", "were", "treated", "with", "50", "μg/mL", "CHX", "for", "the", "indicated", "time", "points", "." ] } ]

PMC11536589

MGST1 production has been found to inhibit ferroptosis by suppressing lipid peroxidation, although it does not impede iron accumulation in PDAC cells (Kuang et al. 2021).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MGST1", "production", "has", "been", "found", "to", "inhibit", "ferroptosis", "by", "suppressing", "lipid", "peroxidation", ",", "although", "it", "does", "not", "impede", "iron", "accumulation", "in", "PDAC", "cells", "(", "Kuang", "et", "al.", "2021", ")", "." ] } ]

PMC11335267

As a negative control, note the absence of Alx3 immunoreactivity in COS cells transfected with empty vector. (

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PMC9622879

Hence, in time slot t, the day-ahead selling price can be determined as with .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hence", ",", "in", "time", "slot", "t", ",", "the", "day-ahead", "selling", "price", "can", "be", "determined", "as", "with", "." ] } ]

PMC9874064

CLSM imags of DNA damage related protein γ-H2AX expression (blue, DAPI; Green, γ-H2AX).

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PMC10759659

In the CHCC-HBV cohort, patients were selected as hepatitis B core antibody (HBcAb) and hepatitis B surface antigen (HBsAg) positive.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "CHCC-HBV", "cohort", ",", "patients", "were", "selected", "as", "hepatitis", "B", "core", "antibody", "(", "HBcAb", ")", "and", "hepatitis", "B", "surface", "antigen", "(", "HBsAg", ")", "positive", "." ] } ]

PMC11467964

Although STS accounts for approximately 1% of adult malignancies, its incidence is relatively higher among adolescents.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Although", "STS", "accounts", "for", "approximately", "1", "%", "of", "adult", "malignancies", ",", "its", "incidence", "is", "relatively", "higher", "among", "adolescents", "." ] } ]

PMC11591052

These activities include anabolic, adaptogenic, hypoglycemic, antioxidant, cardioprotective, hepatoprotective, and neuroprotective effects on healthy tissues .

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PMC10698968

All cell lines were cultured in DMEM high glucose supplemented with 10% lot-selected FBS, 1% L-glutamine, and 1% Penicillin/Streptomycin (all from Life Technologies).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "cell", "lines", "were", "cultured", "in", "DMEM", "high", "glucose", "supplemented", "with", "10", "%", "lot-selected", "FBS", ",", "1", "%", "L-glutamine", ",", "and", "1", "%", "Penicillin/Streptomycin", "(", "all", "from", "Life", "Technologies", ")", "." ] } ]

PMC5261804

Patients without the JAK1-PIK3R1 PPI have improved survival compared to patients who retain this PPI.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "without", "the", "JAK1-PIK3R1", "PPI", "have", "improved", "survival", "compared", "to", "patients", "who", "retain", "this", "PPI", "." ] } ]

PMC9429973

We aim to investigate the efficacy and safety of MCBC conditioning regimen for allo-HSCT in R/R AML patients.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "aim", "to", "investigate", "the", "efficacy", "and", "safety", "of", "MCBC", "conditioning", "regimen", "for", "allo-HSCT", "in", "R/R", "AML", "patients", "." ] } ]

PMC11359735

All data pertinent to this work are contained within this article and are available upon request from M. A. J. F. and P. S. This article contains supporting information (26).

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PMC11352311

The wound areas at both time points were measured using the Image J 1.54 software, and the wound closure rates were calculated.

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PMC9429973

IgG levels against SARS-CoV-2 spike protein were analyzed with Abbott SARS-CoV-2 IgG II Quant-test with ≥50 AU/ml as a threshold for positivity.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "IgG", "levels", "against", "SARS-CoV-2", "spike", "protein", "were", "analyzed", "with", "Abbott", "SARS-CoV-2", "IgG", "II", "Quant-test", "with", "≥50", "AU/ml", "as", "a", "threshold", "for", "positivity", "." ] } ]

PMC11703992

The probability of cell–cell interactions was inferred subsequently.

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PMC11607638

The pancreas was excised, and rat pancreatic acini were isolated by collagenase P (0.2 g L, 10 mL) digestion in a shaking water bath (37°C, 110 cycles per min).

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PMC10421378

For intestinal barrier formation, Caco-2 cells were seeded on the PET membranes (Millicell Cell Culture Inserts, 24 mm diameter, 0.4 µm pore size) (Millipore, Burlington, MA, USA, Merck Group) at an initial density of 4 × 10 cells/cm and cultured for 21 days with a medium change three times a week.

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PMC11604768

Surprisingly, inhibitor treatment did not significantly alter the activation of THRB-1 promoters, despite these being associated with the 5-HT2A projection (Fig. 5a−d, Supplementary Fig. 9F).

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PMC10454535

The Pierce BCA Protein Assay Kit (Thermo Fisher Scientific Inc.) was used to quantify protein samples, which were loaded at 20 μg per well into a 10 well 4–20% Mini-PROTEAN TGX precast gel (Bio-Rad Laboratories, Hercules, CA, USA).

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PMC11190062

Heatmap showing correlation between TLR genes and chromosomal abnormalities in MMRF CoMMpass dataset IA14.

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PMC7039683

Workflow of ATAC-seq in epithelium and mesenchyme cells isolated from palate shelves dissected from E14.5 embryos. (

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PMC11319300

This was taken alongside CTCF data, Supplementary Table S3.

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PMC9429973

We performed adoptive transfer (AT) of TCL1 derived CLL cells into Ebi3 and WT mice, as well as generated the transgenic mouse model Eµ-TCL1-Ebi3.The splenic TME of these mice was characterized using flow cytometry.

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PMC4695073

The cases eligibility criteria were as follows: histologically proven and newly diagnosed NPC without treatment history; locally advanced and no distant metastasis; no serious complications or other primary tumors; treated with chemoradiotherapy containing platinum-based regimens (at least 2 chemotherapy cycles) and regularly followed up in Sun Yat-sen University Cancer Center .

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PMC9429973

Median time to first response was 7 days (range 6–114), and to VGPR or better 54 days (range 6–219).

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PMC11040965

Beyond these limitations, with this paper, we describe a novel pathogenetic mechanism that completes the immunological picture, sketched in our previous reports , of what occurs in the bone marrow during MM development.

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PMC11592837

With mean values close to 1.0, drug-treated Jurkat cells exhibited similar MTCO3 fragment ratios until 2 h; afterward, they reached a plateau (1.61) with ETP and 1.41 with DOX, albeit without statistical significance to the control levels (Figure 7C).

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PMC9429973

The 3-year cumulative incidence of NRM was 20%.

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PMC11155445

Second, via cyclization with α-bromoacetophenone in the presence of trimethylamine under sonication give thiazole-2-imine (18).

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PMC11407042

Take the vial containing A549 cells from the nitrogen tank and thaw the A549 cells at 37°C in a water bath immediately.

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PMC11188874

A P-value ≤ 0.05 is flagged with one star (*) and a P-value ≤ 0.001 is flagged with three stars (***).

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PMC11092382

However, these findings are currently limited to cell-based experimental models, thus, confirmation of the independent anti-HBV activity of sophocarpine in in vivo is still lacking.

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PMC11670407

l Representative IHC images of GPX4 and quantitative analysis of GPX4-positive cells (n = 6) (scale bars: 200 μm and 400 μm).

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PMC10798140

It was also the most effective chemical against cell migration and adhesion, which could play an important role in drug resistance and cell metastasis.

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PMC11593031

Based on patient age, tumor extent, lymph node infiltration or distant metastasis, and the extent of initial surgical tumor resection, NBs are classified into stages according to the International Neuroblastoma Staging System (INSS).

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PMC5417661

It should, however, be noted that OvCar-4 cells treated with a higher 50 nM concentration of NOV202 underwent a massive cell death; at 24, 48 and 72 h time points the average CDI was 28.7%±6.8%, 48.3%±10.7% and 59.3%±13.2%, respectively.

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PMC8728081

The suspended Kajjali and Rasasindura particles were exposed to the adherent NIH3T3 cell line at various concentrations from 10 to 1000 ppm.

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PMC11371747

Cells originating from the CaCo-2 and WiDr cell lines were adapted to grow in RPMI-1640 LF medium supplemented with 2.5 nM l-LV as a representative for a more physiological environment (Backus et al., 2000; Lemos et al., 2008).

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PMC11764090

Preventing ice crystal formation is regarded as a crucial mechanism of cold tolerance in plants.

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PMC9318744

Cell-free virus supernatant was harvested 72 h post-infection when < 70% cytopathic effects were evident.

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PMC10523483

Cell survival of tBHP-treated H1.2 knockout A549 cells and the control group with/without GCLC overexpression, n = 5 per group.

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PMC11286266

The screen identified both anticipated and new candidate genes that regulate ATF6α activation.

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PMC11727000

BRCA2 is a tumor suppressor best known for mutations associated with hereditary breast and ovarian cancer, but mutations are also associated with predisposition to other cancers including childhood leukemia and neuroblastoma .

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PMC4695073

Briefly, total RNA was extracted using TRIzol reagent.

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PMC9429973

Image: Summary/Conclusion: SARS-CoV-2 vaccination in SAA may result in transient decline in blood counts but true relapse is rare.

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PMC9429973

Image: Summary/Conclusion: Our data show similar high efficacy of KRd and KTd in elderly NTE NDMM pts, including no difference in ORR (KRd and KTd, 87.3% and 95%, respectively), PFS and OS.

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PMC10079526

Subsequently, foci were counted within the Macro.

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PMC9429973

Humoral non-response was defined as the absence of a humoral response.

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PMC11367146

p < 0.05 between untreated and IL1β-induced group; *p < 0.05 and **p < 0.01 between IL-1β and VTE treated group.

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PMC11763111

C Flowchart shows that mice (n = 5) were injected intravenously with 3 × 10 CCRF-CEM-Luc-GFP cells, followed by 2.5 × 10 CAR-T/PCDH-T cells five days later.

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PMC11472569

EVs can protect miRNAs from degradation by RNases, unlike naked miRNAs, opening new avenues for overcoming MDR.

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PMC9429973

The CALR mutated patients were younger in age but the median platelet counts, WBC count and Hemoglobin were not statistically different among different mutation groups.

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PMC7759933

The visual analysis of HepG2 spheroids by confocal microscopy verified the time-resolved viability of the cells in a 3D culture, which was more or less stable over the cultivation time.

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PMC11612794

The images in the figures are the maximum intensity projection of the Z-stack generated with Fiji.

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PMC11509224

Diterpene alkaloids were also found from an Okinawan marine sponge (Agelas sp.) .

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PMC7841189

In summary, the present study has provided further evidence that knockdown of LTBP2 inhibits invasion and tumorigenesis in thyroid carcinoma cells.

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PMC7868205

However, genotoxic effects were observed at 0.01–10 mg/mL in BEAS-2B, a normal lung epithelial cell line.

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PMC11637716

Although SBDS mutations are responsible for about 90% of cases, we now know that genetic alterations leading to SDS or SDS‐like phenotypes may also be caused by pathogenic variants in DNAJC21, SRP54 and EFL1. , , , ,

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PMC11790971

Data analytics and machine learning (ML) techniques have become crucial for understanding the complex relationships between cell profiles and the production phenotypes of CHO cell lines.

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PMC10993311

The three DMGMs can be seen in Figure 3.

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PMC8632470

However, various secondary metabolites, e.g., flavonoids, chalcones, coumarins, phenolics, acetylenes, and terpenes, have been identified in different parts of A. keiskei .

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PMC9268620

In summary, the majority of caspase substrates that have been identified are involved in cell regulation, DNA repair, homeostasis, and cell survival.

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PMC9429973

CRS occurred in 68% of patients, was primarily associated with the initial doses, and was mostly Grade (Gr) 1 (51%) or Gr 2 (12%); Gr 3 (3%) and Gr 4 (2%) events were uncommon.

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PMC10605143

In the following days, the medium was replaced with one containing DTHIB at a concentration ranging from 0 to 200 μM in DMSO (max.

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PMC9622879

A mixed integer nonlinear programming (MINLP) model for this scheduling problem was built and solved by using General Algebraic Modeling System (GAMS) software.

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PMC9429973

High transcriptional variability was observed between the PC clusters of the AL patients indicating a high degree of heterogeneity among the AL PCs.

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PMC10729469

Notably, APP/PS1 mice treated with polyclonal Tregs showed significantly increased frequencies of total Tregs compared to untreated APP/PS1 mice.

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PMC7351993

These results are consistent with the RIACS’s ability to provide molecular-vibrational images of cells in a high-speed flow with a subcellular spatial resolution as shown in Fig. 3a–d. Specifically, Fig. 3a shows intracellular lipids (green) in various types of microalgal cells cultured under nitrogen deficiency conditions.

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PMC8427838

Immunofluorescence staining with an antibody against K40-acetylated tubulin in 786-0 cells expressing empty vector (EV) or TMIGD1 revealed that the level of K40-acetylated tubulin in 786-0 cells expressing TMIGD1 was significantly higher than observed for the cells expressing EV (Fig. 5A).

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PMC10114490

The metabolic products of coumarin (7-hydroxycoumarin, assay for CYP2A6 activities), bupropion (hydroxybupropion, assay for CYP2B6 activity), diclofenac (4-hydroxydiclofenac, assay for CYP2C9 activity), chlorzoxazone (6-hydroxychlorzoxazone, assay for CYP2E1 activity) and midazolam (1-hydroxymidazolam, assay for CYP3A4 activity) were determined by liquid chromatography–tandem mass spectrometry.

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PMC10165258

Right: Representation of each condition on a 2D parameter space.

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PMC11247842

The SNPs which were significant both in the current study and eQTL dataset were retained as potential regulatory variants with effect on udder health.

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PMC6835428

The lacunae are in connection with lymphatic capillaries.

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PMC11173119

Air-dried slides were covered with 7–10 μL antifade (Vector, Newark, CA, USA) under a coverslip.

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PMC11258145

The higher the degree of fatty acid saturation, meaning the stiffer the membrane initially, the lower doses of curcumin lead to significant disturbances.

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PMC11190538

Table 9Yogurt samplesCFU*10/mlTotal phenolic (GAE mg/g)Total antioxidants (GAE mg/g)C-PC Remain (%)DPPHABTS24 h7 days14 day24 h7 days14 day24 h7 days14 day24 h7 days14 dayAfter 14 daysC3.475.837.32226.00 ± 18.38307.50 ± 6.36271.50 ± 9.1959.51±2.3163.99 ±2.7458.99 ±3.1742.40 ±1.5175.13 ± 1.5771.68 ±0.73–T13.865.948.83685.00 ±19.80775.50±10.61789.50 ±14.8564.69±4.3262.20 ±5.5658.00 ±4.7262.65 ±7.33129.41±3.64123.09±1.7935.77 ± 3.25T23.355.718.24975.50 ±7.78984.50±7.78907.50±10.6164.04±2.3569.01 ±4.5661.17 ±5.2575.37 ±1.33161.12±2.63148.67±15.3639.08 ± 2.85T31.772.684.211132.50±17.681280.00 ±12.731306.50 ±2.1294.36±3.89108.40 ±4.02109.45 ±3.2385.73 ±4.00189.66±2.21198.48±2.3895.25 ± 3.75T41.912.744.461283.50±13.441444.50 ±9.191562.50 ± 9.19104.98 ±3.96127.21 ±5.09128.88 ±3.8289.97 ±4.66203.74 ±4.12201.38±1.2493.45 ± 2.58NB: All yogurt variants were fermented with L. rhamnosus KU985435, C: control without C-PC, T1: treatment with 150 mg free C-PC, T2: treatment with 300 mg free C-PC, T3: treatment with 150 mg C-PC nanophytosomes (at molar ratio 1:2), T4: treatment with 300 mg C-PC nanophytosomes (at molar ratio 1:2).

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PMC11650848

A high-level semantic language task was adapted for this task to compare differences in neural responses to two sentences.

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PMC9429973

Pts were randomized 1:1, stratified by de novo AML vs. secondary AML, age (60-64 vs 65-70 vs ≥70 yrs), and institution.

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PMC6742971

Figure 2A shows data of an experiment in which we observed strong specific lysis of Me290 target cells even at the high concentration of a low avidity T cell clone (ratio 8:1 of low:high avidity clones).

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PMC11528603

Further evaluation of the effects of SA-EA at IC50 demonstrated time-independent inhibition on proliferation of HL60 cells.

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PMC11621565

The reaction was terminated at 85°C for 5 min.

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PMC9895440

e Area under the curve (AUC) of Calbryte520-AM Ca flux upon stimulation.

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PMC11471176

Iman A. Mansi: Resources, Methodology, Investigation.

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PMC9429973

New potential therapeutic targets (CREBBP, EP300, EZH2, SMARCB1, CD79A/B, BTK, CARD11, MYD88, THFAIP3, PIK3CA, PTEN and JAK) were identified in 55% (11/20) of newly diagnosed patients and in 41.2% (7/17) of relapsed/refractory patients.

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PMC10850553

IA lesions (Unruptured aneurysm which never ruptures, Rupture-prone aneurysm or Ruptured aneurysm) or control arterial bifurcations were harvested subjected to immunohistochemical analyses.

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PMC10158546

Figure 1.In vitro characteristics of ReN human neural progenitor-derived cultures. (

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PMC11670407

In contrast, the results of the wound healing assay demonstrated that compared with the control, OTULIN knockdown alone impeded the migratory capacity of osteosarcoma cells.

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PMC11769516

Fusarium spp.

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PMC11188874

D, Effect of HDAC6 WT, DC, and ΔBUZ mutants on proteasome ChT-like activity in HeLa cells.

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PMC10988555

As the IC50 values in A2780 cells are in the low micromolar range and to ensure ICP-AES sensitivity in terms of limit of detection, the 10× IC50 concentrations were used.

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PMC9429973

On the contrary, the decrease in the number of burst-forming cells of erythrocytopoiesis (BFU-E) after 10 months of cryostorage was significantly lower than at earlier periods of cell suspension thawing.

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PMC11342785

Higher scores indicate a greater degree of disorder.

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PMC3164356

To augment this gene set, we used CHO-K1 transcriptome data to annotate gene structures with the aid of the programs TopHat and Cufflinks.

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