OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC7823217	B. (a) SEM images of cell clusters from suspension culture and from 3D bioprinted constructs. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "B.", "(", "a", ")", "SEM", "imag...
PMC11700247	Enhanced abscopal antitumor effects in A20 lymphoma model with fractionated RT. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Enhanced", "abscopal", "antitumor", "effects", "in", "A20", "lymphoma", "model", ...
PMC11531735	Whole head tumor fluorescent intensity per day and (C) brain tissue images after sacrifice on Day 24 showed significantly reduced tumor growth in treatment group as compared to control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11703992	If untreated, the risk of serious complications increases, including blindness, aortic aneurysm and dissection .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "If", "untreated", ",", "the", "risk", "of",...
PMC11087766	Three of the five PhiPA3 proteins have a homolog in PhiKZ: PhiKZ RecA, gp104, and gp171.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Three", "of", "the", "five", ...
PMC11746948	GAPDH served as the internal control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GAPDH", "served", "as", "the", "internal", "control", "." ] } ]
PMC9844987	Given that the underlying sources of variation are different, for example, genetic and environmental versus stochastic, this indicates that mechanisms that contribute to the buffering of stochastic noise at a single cell level can also contribute to the attenuation of genetic and environmental variation at an individual level.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The same occurs among more than 3000 patients from the US base between the years 2010-2014 vs 2014-2019 (53.96% vs 57.73%, p=0.016, HR 1.099 (1.018 - 1.187) (figure 2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11534035	Research by Ruckriegl et al. demonstrated that GPER1 knockdown in fast-growing invasive cervical cancer cell lines led to increased PAI1 expression (12).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	Patients taking givosiran were excluded.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "taking", "givosiran", "were", "excluded", "." ] } ]
PMC9672323	Glioblastoma exerts an immense immunosuppressive microenvironment, especially on T cells, the most prominent immune cells providing immunity against tumors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Glioblastoma", "exerts"...
PMC11705901	Notwithstanding the null findings for 3 of our chosen SNPs, we did show that polymorphisms of rs1042778 are associated with changes in transcription signal of OXTR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: Here we assess the performance of the EXENT assays for the quantification of M-proteins and whether free light chain evaluation by mass spectrometry (FLC-MS) offers added sensitivity during multiple myeloma monitoring.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9143157	In the MES-SA C9 high tumor xenograft model, which is a highly aggressive tumor with high metastasis potential, P-THP significantly suppressed the tumor growth, which was much better than the effect of THP (Figure 3A), while no apparent body weight loss or acute death occurred (Figure 3B).	[ { "tags": [ "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11791432	Fig. 7In vivo experiments verified the cancerigenetic role of ANXA1. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "7In", "vivo", "experiments", "verified", "the", "cancerigenetic", "role", "of", ...
PMC11279397	Notably, sterols demonstrate potential antiviral effects against various viruses including herpes simplex virus (HSV) , and HBV .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notably", ",", "sterols", ...
PMC10196713	Subsequently, the concentration of cisplatin was increased stepwise for the surviving cells, and the surviving cells up to a concentration of 6 µM were defined as OVK18cis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11468365	As a result, sensitivity and synergy are crucial features to consider when evaluating a drug combination.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "a", "result", ",", "sensitivity", "an...
PMC10362265	Molecular dynamics (MD) simulations, a widely used computational methodology to sample the conformational space of biomolecules , could be of use in analyzing the dynamics of IL18-IL18BP complexes, focusing on the impact of the conformation of the IL18 epitope between residues 68–81.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8345486	Three-dimensional spheroid cell cultures were applied in this study as a particular model for in vitro evaluation of cancer cell chemoresistance .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Three-dimensional", "sp...
PMC10588957	DATS induced pro-apoptotic autophagy via the AMPK/SIRT1 signalling pathway in the human HCC HepG2 cell line.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "DATS", "induced", "pro-apoptotic", "autophagy", "vi...
PMC10873328	Cells (3-5 × 10/well) were seeded in RPMI-1640 without FBS in the top chamber, and were allowed to migrate for 24 to 48 h. The membrane was then washed by PBS for three times and fixed in methyl alcohol for 30 min and stained with crystal violet.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11711063	Comparison of ZG16B transcript levels in normal versus breast cancer tissues (TCGA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Comparison", "of", "ZG16B", "transcript", "levels", "in", "normal", ...
PMC9412887	CSCs are also considered to be in charge of drug resistance and tumor recurrence due to their quiescence, epithelial-to-mesenchymal transition, resistance to DNA damage-induced apoptosis and interactions with the tumor microenvironment .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8751435	In sum, feature of CME‐induced pyroptosis is explored and validated in phenotype and genotype as described above.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "sum", ",", "feature", "of", ...
PMC10243817	Nevertheless, our data suggest an association between eosinophilic inflammation and MEX3B in CRS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Nevertheless", ",", "our", "data", "suggest", "an", "association", ...
PMC9878562	All together, these findings suggest that functional ACKR3 plasma membrane expression is necessary to support efficiently CXCR4-dependent cell migration.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "together", ",", ...
PMC11740207	If pathogenic HPCs accumulate sufficient telomerase-related mutations over their lifespan to drive uncontrolled proliferation and subsequent malignancy, it is plausible that they could proliferate and become malignant within the bone marrow.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10998613	We coexpressed CXCR4-AcGFP1 and β2AR-mCherry in DKO MDA-MB-231 at similar levels as above and incubated the cells for 20 min with 0.1 µM CXCL12 or 5 µM epinephrine, the natural ligands of CXCR4 and β2AR, respectively (Fig. 5A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11128598	HR efficiency was calculated as the ratio of GFP + to DsRed + cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HR", "efficiency", "was", "calculated", "as", "the", "ratio", "o...
PMC10024132	Unless otherwise indicated, all cell culture reagents were purchased from Invitrogen.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Unless", "otherwise", "indicated", ",", "all", "cell", "culture", "reagents", "w...
PMC11470999	Next, we established an experimental model of MBM by injecting B16Br‐Luc cells into the intracarotid artery of C57BL/6 mice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Next", ",", ...
PMC9429973	Aims: In order to evaluate long term influence of anti-CD20 directed therapy on CD20 expression in patients with chronic lymphocytic leukemia who showed only weak MRD responsiveness to therapy in different clinical trials, we aimed to establish a normalization approach based on the instrument standardization to reduce the proportion of technical variance within data.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11628904	Preventing keratinocyte motility by treating burned larvae with medium isotonic to their interstitium limited the spread of tissue damage and reduced burn wound colonisation by C. albicans.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10547921	Chemical structures of cryptophycin analogs 35–40; (B) Binding mode of cryptophycin-52 (36) in complex with tubulin (PDB code 7M20).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10955424	Here, we carried out ex vivo assays to track the capacity of malignant ascites derived from OC patients to promote chemoresistance in OC cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10988808	Quantification of protein expression revealed that overexpressed CCDC25 notably elevated the expression levels of E-cadherin and inhibited the expression of N-cadherin and Vimentin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Quantif...
PMC9429973	The maximum tolerated dose has not been reached.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "maximum", "tolerated", "dose", "has", "not", "been", "reached", "." ] } ]
PMC10391797	HDACi can improve the lysis effect and persistence of CAR-T cells in vivo. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HDACi", "can", "improve", "the", "lysis", "effect", "and", "pers...
PMC11752740	Additionally, exploring the application of this combination therapy in various cancer cell lines could shed light on its broader therapeutic potential.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ...
PMC5916734	The PCR product was purified and ligated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "PCR", "product", "was", "purified", "and", "ligated", "." ] } ]
PMC11484188	no. sc-32233; 1:2,000, Santa Cruz Biotechnology, Inc.), anti-ATG7 (cat.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "no.", "sc-32233", ";", "1:2,000", ",", "Santa", "Cruz", ...
PMC9429973	CRISPR screen findings were confirmed on the level of single molecules, using a competitive molecular in vivo approach and testing the PDX cells with and without knockout in the same mouse.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10810426	This action by anti-viral cytoplasmic proteins is important for host defense, particularly in sentinel cells of the immune system like DCs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "acti...
PMC11082662	The tumor microenvironment is a complex ecosystem that includes tumor cells, immune cells, stromal cells, and various bioactive molecules.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "tumor...
PMC10114490	HDF were isolated as described in detail in http://www.bu.edu/dbin/stemcells/protocols.php.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HDF", "were", "isolated", "as", "described", "in", "detail", "in", "http://www.bu.edu/dbin/stemcells/protocols.ph...
PMC11787651	The resultant propionylated histone peptides are also more hydrophobic and contain less charge, which allows them to better retain on C18 columns, and to be easily fragmented by collisionally activated methods to provide more interpretable tandem mass spectra.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	It is known that in the early stages, the PCR method with fragment analysis (PCR-FA) makes it possible to detect T-cell clonality in 75% of cases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10588957	This suggested that DATS promoted HepG2 cell apoptosis, and the pro-apoptotic ability increased with increasing concentrations.	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "suggested", "that", "DATS", "pro...
PMC9429973	Results: The study group included 15 males (57.7%) and 11 females (42.3%) with a mean age of 43.2 years.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973	Analyses that accounted for the PH assumption violation also indicated a survival benefit for Oral-AZA vs MIDO.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Analyses", "that", "accounted", "for", "the", ...
PMC9100622	Again, only modest effects were observed: Atorvastatin treatment for 72 h had no significant effects on the different cell-cycle phases of A673 and TC71 cells and significantly reduced the proportion of S-phase cells for POE with a parallel increase in G0/G1 cells (Figure 4A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLin...
PMC6160470	Western blot was performed on total cell lysates with antibodies against indicated proteins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Western", "blot", "was", "performed", "on", "total", "cell", "lysates", ...
PMC5854676	FTIR spectra were measured using a NICOLET 6700 FT-IR system.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "FTIR", "spectra", "were", "measured", "using", "a", "NICOLET", "6700", "FT-IR", "system", ...
PMC9429973	DNA was isolated using the Gene Read DNA FFPE Kit panel, Qiagen, USA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "DNA", "was", "isolated", "using", "the", "Gene", "Read", ...
PMC11046454	CD25, an immune regulatory molecule, expressing CAR-J after coculture with CEM cells conjugated with DNA of different density (DNA-CEM), CEM cells conjugated with FITC-DNA of different density (FITC-CEM), or CEM cells plus free FITC-DNA of different concentrations (FITC-DNA + CEM) at 37 °C for 24 h, as assayed with flow cytometry. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "...
PMC11782508	A final extension step at 72 °C for 5 min was included.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "final", "extension", "step", "at", "72", "°", "C", "for", ...
PMC11761919	Viral load in liver.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Viral", "load", "in", "liver", "." ] } ]
PMC11772449	In these studies, whether PFD is combined with cisplatin, it can be clearly observed that it significantly reduces the tumorigenesis of lung cancer and pancreatic cancer and limits the growth of cancer cells, which may be achieved by changing the tumor microenvironment (Kozono et al., 2013; Mediavilla-Varela et al., 2016).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9341513	It is not possible to do this in vivo, and these in silico situations cannot be engineered in reality.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "not",...
PMC11185260	Gray box indicates the treatment period. *	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gray", "box", "indicates", "the", "treatment", "period", ".", "*" ] } ]
PMC11730311	CHO-K1 cells expressing the hCGRP-R were exposed to increasing concentrations of antagonist and a fixed concentration of hαCGRP corresponding to its EC90 (24 pM).	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8494202	Finally, enhanced chemiluminescence was used to detect the cell cycle-related proteins, and signals were captured by Image Lab software.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Finally", ",", "e...
PMC9351137	The quantitative analysis of defects scored in RNAi-treated and control cells (Table 2) is based on the following numbers: at least 100 prometaphases and metaphases for MS, 70 metaphases for CM and ASM, 300 telophases for LIB and CB, and 5500 interphases for MC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7812570	As anticipated, GPI-m36.4 and GPI-FluIgG03 were efficiently expressed on the surface of 293FTTarget cells and did not significantly affect the expression levels of the receptor and coreceptors, as judged by fluorescence intensities (Supplementary Fig. S3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3734024	This study focused on determining the relationship of FasL killer B cells to IL-10-producing B cells and identifying potential growth factors for these cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	Minimal residual disease (MRD) negativity (<0.01%) at any time before disease progression, start of subsequent therapy, or HSCT was centrally reviewed by flow cytometry.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11484188	nos. 7074 and 7076, 1:10,000; Cell Signaling Technology, Inc.) for 2 h at room temperature and washed with TBS three times (10 min each time), then visualized with BeyoECL Plus (Beyotime Institute of Biotechnology).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11740207	While EMT and MET exemplify cellular plasticity, their occurrence does not inherently signify pluripotency.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "While", "EMT", "and", "MET", "exemplify", "cellular", "plas...
PMC9878278	SC were infected with ZIKV at MOI 1 and gene expression of IFN-β, MDA5, RIG-I, TLR3, TLR7, and TLR9 were measured using qRT-PCR at 48 h post-infection (hpi).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11767793	If some of the PEI was released from the Au-PEI@NIST shell, it most likely was not covalently bound, but rather intercalated in the particle shell.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11679326	Enzymatic addition of sugar residues to biopolymers has been found in all domains of life.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Enzymatic", "addition", "of", "sugar", "residues", "to", "b...
PMC11789597	The surface level of CD325 (CDH2) in MM cells expressing shNC or shCAV1 was determined using flow cytometry.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "surface", "level", ...
PMC7961460	The newly secreted HA interacts with specific receptors (i.e., CD44 and RHAMM) and activates signal transduction pathways that promote the malignant phenotype .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC7039683	Figure 5—figure supplement 2.Summary of ATAC-seq in HIOEC and HEPM cells.(A) Heatmap plots of ATAC-seq of HIOEC- and HEPM-specific NFRs. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": ...
PMC7757104	Based on these results, we hypothesized that OPNc cells may be suitable candidates for novel approaches to CDDP treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Based", "on", "these", ...
PMC11755467	Using alternative methods and cellular systems, a number of studies have described additional miRNAs with the potential to target HIV-1 RNA, thereby impacting HIV-1 replication .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11658074	p < 0.05, ***p < 0.001 AT has a protective effect on the skin under ultraviolet B (UVB) irradiation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11686380	Dissected cortices were disrupted mechanically and enzymatically with trypsin and DNase I for 15 min at 37 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Dissected", "cortices", "were", "...
PMC11792766	Summary of no‐observed‐adverse‐effect‐concentrations (NOAECs) for exposed HepG2 and Caco‐2 cell lines to ethanol as determined via the MTT, lactate dehydrogenase (LDH), and neutral red uptake (NRU) assays.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11320834	All measurements were repeated three times.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "measurements", "were", "repeated", "three", "times", "." ] } ]
PMC11397654	These derivatives could be further used to develop inhibiting agents able to prevent the HPV L1 pentamer formation, targeting the viral infection in its initial phase.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10582049	The cluster of ADH1B cells was formed by 234 (71.8%) and 92 (28.2%) CAFs from the indolent and aggressive tumors, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11478724	In recent years, MicroRNAs have been the focus of numerous studies because of their potential role in cancer, diagnosis, prognosis, and gene therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9065483	Representative images can be found in Figure S11. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Representative", "images", "can", "be", "found", "in", "Figure", "S11", ".", "(" ] } ]
PMC11756937	The cells were fed every other day post-nucleofection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cells", "were", "fed", "every", "other", "day", "post-nucleofection", "." ] } ]
PMC9611901	The main problem with glutaraldehyde is that this compound causes DNA–protein cross-linking .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "main", "problem", "with", "glutaraldehyde", "is", "that", ...
PMC11782508	MCF7 cells were treated with a defined concentration of purified azurin (77.81 ± 0.56 µg/mL) for 48 h. Following treatment, cells were harvested, fixed with 66% ethanol (v/v) for at least 2 h at 4 °C, and stored until analysis.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8524093	Interestingly, despite the role of cellular immunity to CHIKV infection, an acute lymphopenia during the initial phase of disease is usually observed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10957991	In agreement with this, in mammary epithelial cells TRPV4 affected differentiation of α-SMA-expressing myoepithelial cells stiffness-dependently and the levels of TRPV4 itself were also dependent on the rigidity of the underlying matrix (Figs. 1, 2, S3, S4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11471176	This discerning observation was gleaned from an activity kit employed within a concomitant research endeavor conducted by a parallel investigative group, albeit the specific data remains regrettably undisclosed at this juncture.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	In univariate analysis, Int-risk cytogenetics and NPM1 at Dx, and MRD response on-study, were significantly prognostic of LTS in both arms, whereas MRD– status at BL (post-IC) was associated with LTS only in the PBO arm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11047729	It has antioxidant, inflammatory, and autoimmune properties and can be used in therapy for neurogenerative diseases and several types of cancer .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", ...
PMC7642379	A comparison between gene expression fold changes and copy number variation of the differentially expressed genes (log2-fold change > ± 1) for each progeny cell line compared to HEK293 showed a trend of gained gene copies amongst the majority of genes with up-regulated mRNA levels (Supplementary Fig. S4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11365427	Impact of VAPB expression interference on cell proliferation assessed by EDU assay. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Impact", "of", "VAPB", "expression", "interference", "on", "cell", "prolife...
PMC11721587	K and L) ChIP qPCR analysis of chromatin-associated Gli2, Sufu, and Ulk3 on Ptch1 (K) and Gli1 (L) promoters in control or Gli2-depleted NIH3T3 cells treated with or without Shh.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10932641	The cells were washed with PBS three times, and the serum-free medium was replaced and cultured in a 5% CO2 incubator with saturated humidity at 37 ℃.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11401350	T cells were stimulated by IL-7/IL-15 or through the TCR and transduced as outlined in Fig. 2C with the indicated vectors at equivalent viral particle levels (10 ng p24).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11519077	As a result, IL-1β-induced Caco-2 cells can be proposed as a cell model of IBD .	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "a", "result", ",", "IL-1β-induced", "Ca...
PMC9960565	Then, an aqueous solution of 0.28 g of AgNO3 (1.69 mmol, 2 eq. mol) in 6.5 mL of UPW was added dropwise to the mixture under stirring.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7823217

B. (a) SEM images of cell clusters from suspension culture and from 3D bioprinted constructs. (

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PMC11700247

Enhanced abscopal antitumor effects in A20 lymphoma model with fractionated RT. (

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PMC11531735

Whole head tumor fluorescent intensity per day and (C) brain tissue images after sacrifice on Day 24 showed significantly reduced tumor growth in treatment group as compared to control.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11703992

If untreated, the risk of serious complications increases, including blindness, aortic aneurysm and dissection .

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PMC11087766

Three of the five PhiPA3 proteins have a homolog in PhiKZ: PhiKZ RecA, gp104, and gp171.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Three", "of", "the", "five", ...

PMC11746948

GAPDH served as the internal control.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GAPDH", "served", "as", "the", "internal", "control", "." ] } ]

PMC9844987

Given that the underlying sources of variation are different, for example, genetic and environmental versus stochastic, this indicates that mechanisms that contribute to the buffering of stochastic noise at a single cell level can also contribute to the attenuation of genetic and environmental variation at an individual level.

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PMC9429973

The same occurs among more than 3000 patients from the US base between the years 2010-2014 vs 2014-2019 (53.96% vs 57.73%, p=0.016, HR 1.099 (1.018 - 1.187) (figure 2).

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PMC11534035

Research by Ruckriegl et al. demonstrated that GPER1 knockdown in fast-growing invasive cervical cancer cell lines led to increased PAI1 expression (12).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC9429973

Patients taking givosiran were excluded.

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "taking", "givosiran", "were", "excluded", "." ] } ]

PMC9672323

Glioblastoma exerts an immense immunosuppressive microenvironment, especially on T cells, the most prominent immune cells providing immunity against tumors.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Glioblastoma", "exerts"...

PMC11705901

Notwithstanding the null findings for 3 of our chosen SNPs, we did show that polymorphisms of rs1042778 are associated with changes in transcription signal of OXTR.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Aims: Here we assess the performance of the EXENT assays for the quantification of M-proteins and whether free light chain evaluation by mass spectrometry (FLC-MS) offers added sensitivity during multiple myeloma monitoring.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9143157

In the MES-SA C9 high tumor xenograft model, which is a highly aggressive tumor with high metastasis potential, P-THP significantly suppressed the tumor growth, which was much better than the effect of THP (Figure 3A), while no apparent body weight loss or acute death occurred (Figure 3B).

[ { "tags": [ "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...

PMC11791432

Fig. 7In vivo experiments verified the cancerigenetic role of ANXA1. (

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PMC11279397

Notably, sterols demonstrate potential antiviral effects against various viruses including herpes simplex virus (HSV) , and HBV .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notably", ",", "sterols", ...

PMC10196713

Subsequently, the concentration of cisplatin was increased stepwise for the surviving cells, and the surviving cells up to a concentration of 6 µM were defined as OVK18cis.

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PMC11468365

As a result, sensitivity and synergy are crucial features to consider when evaluating a drug combination.

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PMC10362265

Molecular dynamics (MD) simulations, a widely used computational methodology to sample the conformational space of biomolecules , could be of use in analyzing the dynamics of IL18-IL18BP complexes, focusing on the impact of the conformation of the IL18 epitope between residues 68–81.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8345486

Three-dimensional spheroid cell cultures were applied in this study as a particular model for in vitro evaluation of cancer cell chemoresistance .

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PMC10588957

DATS induced pro-apoptotic autophagy via the AMPK/SIRT1 signalling pathway in the human HCC HepG2 cell line.

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PMC10873328

Cells (3-5 × 10/well) were seeded in RPMI-1640 without FBS in the top chamber, and were allowed to migrate for 24 to 48 h. The membrane was then washed by PBS for three times and fixed in methyl alcohol for 30 min and stained with crystal violet.

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PMC11711063

Comparison of ZG16B transcript levels in normal versus breast cancer tissues (TCGA).

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PMC9412887

CSCs are also considered to be in charge of drug resistance and tumor recurrence due to their quiescence, epithelial-to-mesenchymal transition, resistance to DNA damage-induced apoptosis and interactions with the tumor microenvironment .

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PMC8751435

In sum, feature of CME‐induced pyroptosis is explored and validated in phenotype and genotype as described above.

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PMC10243817

Nevertheless, our data suggest an association between eosinophilic inflammation and MEX3B in CRS.

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PMC9878562

All together, these findings suggest that functional ACKR3 plasma membrane expression is necessary to support efficiently CXCR4-dependent cell migration.

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PMC11740207

If pathogenic HPCs accumulate sufficient telomerase-related mutations over their lifespan to drive uncontrolled proliferation and subsequent malignancy, it is plausible that they could proliferate and become malignant within the bone marrow.

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PMC10998613

We coexpressed CXCR4-AcGFP1 and β2AR-mCherry in DKO MDA-MB-231 at similar levels as above and incubated the cells for 20 min with 0.1 µM CXCL12 or 5 µM epinephrine, the natural ligands of CXCR4 and β2AR, respectively (Fig. 5A).

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PMC11128598

HR efficiency was calculated as the ratio of GFP + to DsRed + cells.

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PMC10024132

Unless otherwise indicated, all cell culture reagents were purchased from Invitrogen.

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PMC11470999

Next, we established an experimental model of MBM by injecting B16Br‐Luc cells into the intracarotid artery of C57BL/6 mice.

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PMC9429973

Aims: In order to evaluate long term influence of anti-CD20 directed therapy on CD20 expression in patients with chronic lymphocytic leukemia who showed only weak MRD responsiveness to therapy in different clinical trials, we aimed to establish a normalization approach based on the instrument standardization to reduce the proportion of technical variance within data.

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PMC11628904

Preventing keratinocyte motility by treating burned larvae with medium isotonic to their interstitium limited the spread of tissue damage and reduced burn wound colonisation by C. albicans.

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PMC10547921

Chemical structures of cryptophycin analogs 35–40; (B) Binding mode of cryptophycin-52 (36) in complex with tubulin (PDB code 7M20).

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PMC10955424

Here, we carried out ex vivo assays to track the capacity of malignant ascites derived from OC patients to promote chemoresistance in OC cells.

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PMC10988808

Quantification of protein expression revealed that overexpressed CCDC25 notably elevated the expression levels of E-cadherin and inhibited the expression of N-cadherin and Vimentin.

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PMC9429973

The maximum tolerated dose has not been reached.

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PMC10391797

HDACi can improve the lysis effect and persistence of CAR-T cells in vivo. (

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PMC11752740

Additionally, exploring the application of this combination therapy in various cancer cell lines could shed light on its broader therapeutic potential.

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PMC5916734

The PCR product was purified and ligated.

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PMC11484188

no. sc-32233; 1:2,000, Santa Cruz Biotechnology, Inc.), anti-ATG7 (cat.

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PMC9429973

CRISPR screen findings were confirmed on the level of single molecules, using a competitive molecular in vivo approach and testing the PDX cells with and without knockout in the same mouse.

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PMC10810426

This action by anti-viral cytoplasmic proteins is important for host defense, particularly in sentinel cells of the immune system like DCs.

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PMC11082662

The tumor microenvironment is a complex ecosystem that includes tumor cells, immune cells, stromal cells, and various bioactive molecules.

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PMC10114490

HDF were isolated as described in detail in http://www.bu.edu/dbin/stemcells/protocols.php.

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PMC11787651

The resultant propionylated histone peptides are also more hydrophobic and contain less charge, which allows them to better retain on C18 columns, and to be easily fragmented by collisionally activated methods to provide more interpretable tandem mass spectra.

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PMC9429973

It is known that in the early stages, the PCR method with fragment analysis (PCR-FA) makes it possible to detect T-cell clonality in 75% of cases.

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PMC10588957

This suggested that DATS promoted HepG2 cell apoptosis, and the pro-apoptotic ability increased with increasing concentrations.

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PMC9429973

Results: The study group included 15 males (57.7%) and 11 females (42.3%) with a mean age of 43.2 years.

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PMC9429973

Analyses that accounted for the PH assumption violation also indicated a survival benefit for Oral-AZA vs MIDO.

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PMC9100622

Again, only modest effects were observed: Atorvastatin treatment for 72 h had no significant effects on the different cell-cycle phases of A673 and TC71 cells and significantly reduced the proportion of S-phase cells for POE with a parallel increase in G0/G1 cells (Figure 4A).

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PMC6160470

Western blot was performed on total cell lysates with antibodies against indicated proteins.

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PMC5854676

FTIR spectra were measured using a NICOLET 6700 FT-IR system.

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PMC9429973

DNA was isolated using the Gene Read DNA FFPE Kit panel, Qiagen, USA.

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PMC11046454

CD25, an immune regulatory molecule, expressing CAR-J after coculture with CEM cells conjugated with DNA of different density (DNA-CEM), CEM cells conjugated with FITC-DNA of different density (FITC-CEM), or CEM cells plus free FITC-DNA of different concentrations (FITC-DNA + CEM) at 37 °C for 24 h, as assayed with flow cytometry. (

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PMC11782508

A final extension step at 72 °C for 5 min was included.

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PMC11761919

Viral load in liver.

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PMC11772449

In these studies, whether PFD is combined with cisplatin, it can be clearly observed that it significantly reduces the tumorigenesis of lung cancer and pancreatic cancer and limits the growth of cancer cells, which may be achieved by changing the tumor microenvironment (Kozono et al., 2013; Mediavilla-Varela et al., 2016).

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PMC9341513

It is not possible to do this in vivo, and these in silico situations cannot be engineered in reality.

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PMC11185260

Gray box indicates the treatment period. *

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PMC11730311

CHO-K1 cells expressing the hCGRP-R were exposed to increasing concentrations of antagonist and a fixed concentration of hαCGRP corresponding to its EC90 (24 pM).

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PMC8494202

Finally, enhanced chemiluminescence was used to detect the cell cycle-related proteins, and signals were captured by Image Lab software.

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PMC9351137

The quantitative analysis of defects scored in RNAi-treated and control cells (Table 2) is based on the following numbers: at least 100 prometaphases and metaphases for MS, 70 metaphases for CM and ASM, 300 telophases for LIB and CB, and 5500 interphases for MC.

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PMC7812570

As anticipated, GPI-m36.4 and GPI-FluIgG03 were efficiently expressed on the surface of 293FTTarget cells and did not significantly affect the expression levels of the receptor and coreceptors, as judged by fluorescence intensities (Supplementary Fig. S3).

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PMC3734024

This study focused on determining the relationship of FasL killer B cells to IL-10-producing B cells and identifying potential growth factors for these cells.

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PMC9429973

Minimal residual disease (MRD) negativity (<0.01%) at any time before disease progression, start of subsequent therapy, or HSCT was centrally reviewed by flow cytometry.

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PMC11484188

nos. 7074 and 7076, 1:10,000; Cell Signaling Technology, Inc.) for 2 h at room temperature and washed with TBS three times (10 min each time), then visualized with BeyoECL Plus (Beyotime Institute of Biotechnology).

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PMC11740207

While EMT and MET exemplify cellular plasticity, their occurrence does not inherently signify pluripotency.

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PMC9878278

SC were infected with ZIKV at MOI 1 and gene expression of IFN-β, MDA5, RIG-I, TLR3, TLR7, and TLR9 were measured using qRT-PCR at 48 h post-infection (hpi).

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PMC11767793

If some of the PEI was released from the Au-PEI@NIST shell, it most likely was not covalently bound, but rather intercalated in the particle shell.

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PMC11679326

Enzymatic addition of sugar residues to biopolymers has been found in all domains of life.

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PMC11789597

The surface level of CD325 (CDH2) in MM cells expressing shNC or shCAV1 was determined using flow cytometry.

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PMC7961460

The newly secreted HA interacts with specific receptors (i.e., CD44 and RHAMM) and activates signal transduction pathways that promote the malignant phenotype .

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PMC7039683

Figure 5—figure supplement 2.Summary of ATAC-seq in HIOEC and HEPM cells.(A) Heatmap plots of ATAC-seq of HIOEC- and HEPM-specific NFRs. (

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PMC7757104

Based on these results, we hypothesized that OPNc cells may be suitable candidates for novel approaches to CDDP treatment.

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PMC11755467

Using alternative methods and cellular systems, a number of studies have described additional miRNAs with the potential to target HIV-1 RNA, thereby impacting HIV-1 replication .

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PMC11658074

p < 0.05, ***p < 0.001 AT has a protective effect on the skin under ultraviolet B (UVB) irradiation.

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PMC11686380

Dissected cortices were disrupted mechanically and enzymatically with trypsin and DNase I for 15 min at 37 °C.

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PMC11792766

Summary of no‐observed‐adverse‐effect‐concentrations (NOAECs) for exposed HepG2 and Caco‐2 cell lines to ethanol as determined via the MTT, lactate dehydrogenase (LDH), and neutral red uptake (NRU) assays.

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PMC11320834

All measurements were repeated three times.

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PMC11397654

These derivatives could be further used to develop inhibiting agents able to prevent the HPV L1 pentamer formation, targeting the viral infection in its initial phase.

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PMC10582049

The cluster of ADH1B cells was formed by 234 (71.8%) and 92 (28.2%) CAFs from the indolent and aggressive tumors, respectively.

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PMC11478724

In recent years, MicroRNAs have been the focus of numerous studies because of their potential role in cancer, diagnosis, prognosis, and gene therapy.

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PMC9065483

Representative images can be found in Figure S11. (

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PMC11756937

The cells were fed every other day post-nucleofection.

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PMC9611901

The main problem with glutaraldehyde is that this compound causes DNA–protein cross-linking .

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PMC11782508

MCF7 cells were treated with a defined concentration of purified azurin (77.81 ± 0.56 µg/mL) for 48 h. Following treatment, cells were harvested, fixed with 66% ethanol (v/v) for at least 2 h at 4 °C, and stored until analysis.

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PMC8524093

Interestingly, despite the role of cellular immunity to CHIKV infection, an acute lymphopenia during the initial phase of disease is usually observed.

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PMC10957991

In agreement with this, in mammary epithelial cells TRPV4 affected differentiation of α-SMA-expressing myoepithelial cells stiffness-dependently and the levels of TRPV4 itself were also dependent on the rigidity of the underlying matrix (Figs. 1, 2, S3, S4).

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PMC11471176

This discerning observation was gleaned from an activity kit employed within a concomitant research endeavor conducted by a parallel investigative group, albeit the specific data remains regrettably undisclosed at this juncture.

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PMC9429973

In univariate analysis, Int-risk cytogenetics and NPM1 at Dx, and MRD response on-study, were significantly prognostic of LTS in both arms, whereas MRD– status at BL (post-IC) was associated with LTS only in the PBO arm.

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PMC11047729

It has antioxidant, inflammatory, and autoimmune properties and can be used in therapy for neurogenerative diseases and several types of cancer .

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PMC7642379

A comparison between gene expression fold changes and copy number variation of the differentially expressed genes (log2-fold change > ± 1) for each progeny cell line compared to HEK293 showed a trend of gained gene copies amongst the majority of genes with up-regulated mRNA levels (Supplementary Fig. S4).

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PMC11365427

Impact of VAPB expression interference on cell proliferation assessed by EDU assay. (

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PMC11721587

K and L) ChIP qPCR analysis of chromatin-associated Gli2, Sufu, and Ulk3 on Ptch1 (K) and Gli1 (L) promoters in control or Gli2-depleted NIH3T3 cells treated with or without Shh.

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PMC10932641

The cells were washed with PBS three times, and the serum-free medium was replaced and cultured in a 5% CO2 incubator with saturated humidity at 37 ℃.

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PMC11401350

T cells were stimulated by IL-7/IL-15 or through the TCR and transduced as outlined in Fig. 2C with the indicated vectors at equivalent viral particle levels (10 ng p24).

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PMC11519077

As a result, IL-1β-induced Caco-2 cells can be proposed as a cell model of IBD .

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PMC9960565

Then, an aqueous solution of 0.28 g of AgNO3 (1.69 mmol, 2 eq. mol) in 6.5 mL of UPW was added dropwise to the mixture under stirring.

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