OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC4360730	These slims also allow for a wider exposure and overview of the ENCODE data (https://www.encodeproject.org/help/getting-started#browse).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "slims", "also", "allow", "for", "a...
PMC11723947	Treg can also act indirectly on T cells, by modulating dendritic cell maturation and function using co-inhibitory receptors such as CTLA-4 or Tim3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11543885	This reflects a crucial experiment to investigate the ability of APEX2 labeling to capture changes in the microenvironment of activated versus inactivated NLRP3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", ...
PMC11013014	Acid 20 (0.59 g, 0.289 mmol), pentafluorophenol (0.58 g, 0.318 mmol), and EDC (0.58 g, 0.318 mmol) are mixed in DMF (5 mL) at 0 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8623816	Thus, the use of RsRV5 as a biological control agent for rice sheath blight still needs to overcome great difficulties.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "the"...
PMC11541241	The target of rapamycin (TOR) was first identified in yeast (Saccharomyces cerevisiae) by screening mutants insensitive to rapamycin (RAP), which is a medicine isolated from the bacterium Streptomyces hygroscopicus and efficiently represses TOR kinase activity (Heitman et al., 1991; Sehgal et al., 1975; Vézina et al., ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11686380	Cells were then fixed and subjected to immunostaining with anti-GFP and anti-Myc.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "then", "fixed", "and", "subjected", "to", "immunostaining", "wi...
PMC11429241	The experiment was repeated twice.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "experiment", "was", "repeated", "twice", "." ] } ]
PMC9429973	Human-curated natural language processing with assistance from machine learning algorithms was used to extract EMR data.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Human-curated", "natural", "language", "processing", "with",...
PMC11686380	p < 0.0001 (vs control) by one-way ANOVA and Dunnett’s post hoc test. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "p", "<", "0.0001", "(", "vs", "control", ...
PMC11786704	Images of skin wounds treated with PBS (control), PC solution and PC capsules in an acute wound model. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Images", "of...
PMC9429973	Two pts (1R/R and 5R/R) in the R/R cohort experienced PD and subsequently succumbed to lymphoma, both of which harbored TP53 mutations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	Aims: The purpose of this study is to examine the effects of macrophage depletion on bone marrow and splenic erythropoiesis under chronic stress conditions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11228511	Mean ± SD. ****	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mean", "±", "SD", ".", "", "", "", "" ] } ]
PMC6889484	Flow cytometry analysis of the transduced cells showed that expression of the A3 (A3dr) or 3G (3Gdr) truncated proteins of A3G-D128K in the lentivector producer cells resulted in <2-fold inhibition of transduction (∼50% and ∼87% eYFP cells compared to cells transduced with eYFPip, respectively).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612794	In M phase, the Dsn1 basic motif is precluded from the Nsl1 acidic surface by the CENP-T and Dsn1 dual phosphoregulation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "M", ...
PMC11747949	All these proangiogenic and pro‐inflammatory chemokines play a role in osteosarcoma progression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "these", "proangiogenic", "and", "pro‐inflammatory", "chemokines", "play", "a", ...
PMC8193046	For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	Methods: NGS-based MRD measurements (clonoSEQ) from peripheral blood (PB) at follow-up month 3 were grouped into uMRD <10 (MRD6), 10 ≤ and <10 (MRD4/5), and detectable MRD ≥10 (MRD+).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11055443	However, it is necessary to further investigate the activation or inhibition of the inflammatory cytokines production and also the signaling pathways involved in Caco-2 cells treated with secretome in future studies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", ...
PMC10728200	Further studies are needed to fully elucidate the mechanisms underlying the impact of RSL3 on GPX4 mRNA levels and to better understand the intricate regulatory networks involved in ferroptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9954564	Except for Roas2, they are all expressed in the skin (Human Protein Atlas portal—http://www.proteinatlas.org (accessed on 1 December 2021)).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11634794	However, overexpression of the LAMP1 gene led to a decrease in the expression of LC3C instead, which was restored upon subsequent knockdown of LAMP1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11803918	Upon red light irradiation, hybrid exosomes could produce a large amount of O2 in a time-dependent manner (Figure 5A–C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11361748	Briefly, cells were incubated with PLA probes for 1 h at 37°C, with the ligation mixture for 30 min at 37°C, and with the amplification mixture for 100 min at 37°C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10998613	In contrast, when CXCR4-VN was coexpressed with CXCR4-VC, the BiFC signal was observed in the plasma membrane and in the cytoplasm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC11257203	Then, cytochalasin-B (3 μg/mL) was added to the samples, leading to the inhibition of cytokinesis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "cytochalasin-B", "("...
PMC11755467	For annealing, equimolar concentrations of both fragments were incubated at 95 °C for 5 min and allowed to cool to room temperature for at least 1 h. 10 units of T4 dsRNA Ligase 2 (NEB) were then added to the solution and incubated for 1 h at 37 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Additionally, HSP-CAR30 has shown promising efficacy in heavily treated HL patients that is being explored in a phase 2 trial already started.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additio...
PMC10955424	Ascites fluid derived from OC patients promoted chemoresistance causing moderate (20 %) and significant (30 %) reduction in cPARP levels as summarized in Fig. 1E.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Results: A total of 158 patients were treated with R-CHOP during the study period but 20 patients were excluded because of poor records (N = 8), planned R-CHOP cycle number other than six (N = 7, e.g., abbreviated cycles plus radiation therapy), and treatment incompletion (N = 5).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10898159	This mechanism of ETV1 in GIST differs from that in the other ETS-dependent tumors, such as genomic translocation or amplification in prostate cancer .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	Overall response rate and safety profile were evaluated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overall", "response", "rate", "and", "safety", "profile", "were", "evaluated", "." ] } ]
PMC11650848	When comparing intervention groups for these genotypes against symbol search and cancellation scores there were significant differences through ANOVA analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "When", "comparing", "interve...
PMC11574271	Fig. 7The inhibitory effect of BMS-777607 on RON-mediated activity and the suppressive effect of ectopic expression of miR-659-3p on bladder cancer cells tumorigenic in vivo.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11745600	To develop a novel therapy for diabetes (particularly through cell transplantation), it is crucial to assess the effectiveness and safety of the cells using diabetic animal models.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11547972	This theory may explain why amygdalin has been shown to exert synergism under differing conditions, including drugs with different modes of action.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", ...
PMC11394730	Piperine has the potential to increase ROS as well as intracellular calcium levels, which can activate the Fenton reaction and lead to cell death.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11342785	H, demonstration of the PKA-regulated synMAP circuit design from (G).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "H", ",", "demonstration", "of", "the", "PKA-regulated", "synMAP", "circuit"...
PMC8609870	Gu et al. observed that polymorphisms in lncRNA HULC may be related to the susceptibility to RSA in the Southern Chinese population.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gu", "et", ...
PMC8584666	GPI-80 belongs to the VNN1/pantetheinase family.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GPI-80", "belongs", "to", "the", "VNN1/pantetheinase", "family", "." ] } ]
PMC9429973	CD3+ T-cell proliferation as measured by Ki67 expression and pSYK activation were assessed by quantitative single-cell immunofluorescence microscopy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CD3", "+", "T-cell", "proliferati...
PMC10723784	In addition, carboplatin in combination with 100 nM CBG achieved significantly lower (p < .001) IC50 values of 36.5 ± 3.2 μM, 32.1 ± 2.7 μM, and 29.5 ± 0.5 μM at 48, 72, and 96 h, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11721295	To obtain mechanistic insight into fibroblast reprogramming, we subclustered the fibroblast population from the scRNA-seq data set and visualized it by UMAP (Figure 3D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11745823	According to experimental needs, the transfected cells were specifically treated to detect the activity of the target regulatory sequence under different conditions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Accordi...
PMC9429973	Kaplan-Meier method was used to assess TTP and generate survival curves, with log-rank test for comparison between groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Kaplan-Meier", "method", "was", "...
PMC9119314	In addition, 4–6 exhibited potent (nM) activity against T. brucei with good selectivity with respect to Hep G2 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O" ], "tokens": [ "...
PMC9429973	Results: A strong positive correlation between elevated levels of CD33CD11bCD14CD15monocytic MDSCs, but not CD33CD11bCD14CD15 granulocytic MDSC and MDR was depicted in non-responder patients compared to responder cohorts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Patients in two groups presented the same overall response rate but a higher possibility of complete remission was observed in allogenic ones.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "...
PMC10079526	Cells were fixed and immunostained for DNMT1 and DNA double strand break marker γH2Ax.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "fixed", "and", "immunostained", "for", "DNMT1", ...
PMC9592219	The invasion ability of HCC cells was evaluated by Transwell assay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "invasion", "ability", "of", "HCC", "cells", "was", "evaluated", "by", "Transwe...
PMC11711127	The phenomena of molecular mimicry as a precedent for some autoimmune diseases may provide contextual evidence for this (2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "phenomena", ...
PMC9000591	Among the obtained fractions, SE4 showed the most notable antioxidant activity, followed by SE3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Among", "the", "obtained", "fractions", ",", "SE4", ...
PMC7342409	The above-mentioned imatinib-resistant cell lines and GIST882 were inoculated into nude mice to observe their tumorigenicity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "above-mentioned", "imatinib-resistant", "cell", ...
PMC10671321	The cells were seeded in plates coated with collagen type I. This medium was added at 90% of cell confluence.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cells", "w...
PMC9429973	Summary/Conclusion: Elevated levels of complement biomarkers were associated with a worse TPO-RA treatment response.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Summary/Conclusion", ":", "Elevated", "levels", "of", "complement...
PMC11783017	The data that support the findings of this study are available from the corresponding author upon reasonable request.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "data", "that", "support", "the"...
PMC9429973	Median time to count recovery in R/R AML pts was 33 days (range, 24-78).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Median", "time", "to", "count", ...
PMC11401350	T cells were activated either using anti-CD3 and anti-CD28 antibodies, or IL-7/IL-15 cytokine stimulation for 3 days.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "T", "cells", "were", "activated", "eit...
PMC10568263	The obtained products were collected by centrifugation and washed several times with ethanol and DI water.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "obtained", "products", "were", "collected", "by...
PMC8270637	Subsequently, H9 cells were centrifuged and resuspended in 500 μL of PBS.	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Subsequently", ",", "H9", "cells", "were", "centrifuged", "and", "...
PMC11746948	h Immunoblots of GPX4 and ZDHHC20 in A375 cells infected with lentiviruses encoding empty vector or ZDHHC20.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "h", "Immunoblots", "of", "GPX4", "and", ...
PMC9503669	B9 inhibited wild-type HIV-1 replication with an IC50 value in the three-digit nanomolar range in two different cell lines but did not affect replication of Nef-defective HIV-1, supporting a Nef-dependent mechanism of action.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11754094	= −0.15), resulting in a low correlation with small indels (Pearson corr.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "=", "−0.15", ")", ",", "resulting", "in", "a", "low",...
PMC11513571	All samples were performed in duplicate wells for each stimulant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "samples", "were", "performed", "in", "duplicate", "wells", "for", "each", "stimulant", ...
PMC11634794	Nevertheless, at present, we have only preliminarily demonstrated the correlation between LAMP1 and the autophagy-related gene LC3C at the protein expression level.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11727145	Furthermore, the purpose set forth herein was to simplify the model.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "the", "purpose", "set", "forth", "herein", "was", "to", ...
PMC11740207	This phenomenon has been observed in various malignancies, including gliomas and mammary tumors, where AD helps control MSC populations and contributes to the heterogeneity of the tumor microenvironment (Tassan et al., 2017; Castro-Oropeza et al., 2018; Majumdar and Liu, 2020; Hitomi et al., 2021; Li et al., 2022; Chao...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11537649	Lnc NEAT1 was knocked down in A375 cells with miR-152-3p inhibitor or CDK6 overexpressing. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lnc", "NEAT1", "was", "knocked", "down",...
PMC11377827	The catalytic sites Cys110, His668 and Asn108 are labelled. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "catalytic", "sites", "Cys110", ",", "His668", "and", "Asn108", "are", "labelle...
PMC10882807	Next, the slices were incubated with anti-EIF4A3 (1:100, Proteintech, China) overnight at 4℃ and subsequently with horseradish peroxidase-conjugated anti-mouse/rabbit secondary antibody (1:1000, Changdao Biotechnology, China) for 1 h at room temperature.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10218459	The cell viability decreased with the increasing duration of treatment with CPP.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cell", "viability", "decreased", "with", "the", "increasing", "duration", ...
PMC11343332	The results were analyzed by the comparative CT method, and the 2−∆∆CT method was used for the fold change calculation described by Schmittgen and Livak .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11659734	Nine concentrations of BPE were selected for the chromosome aberration test, based on the results of the in vitro micronucleus test (range from 1.25 to 100 μM).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9646302	GST-HA-RAC1 and FLAG-LAPTM5 were overexpressed, and the aforementioned protocol was repeated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GST-HA-RAC1", "and", "FLAG-LAPTM5", "were", "overexpressed", ",", "and", "the", ...
PMC6461034	Second, in a more clinical application, INKA scoring was applied to pTyr‐phosphoproteomic data on patient tumor biopsies (Fig 5C and D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11534035	The knockdown group showed 93.04±2.613% of the cells remained vital compared to the control group's 100% (p<0.05).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "knock...
PMC6742971	The percentage of specific lysis was calculated as 100 × (experimental – spontaneous release)/(total – spontaneous release).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "percentage", "of", "specif...
PMC11190538	For measurements, the ABTS solution was diluted with ethanol to achieve an absorbance of 0.700 at 734 nm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "measurements", ",", "the",...
PMC9429973	Results: The median age at treatment was 58 [22-88] years.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "The", "median", "age", "at", "treatment", ...
PMC7602170	Gupta and colleagues confirmed that a considerable number of GIST cells enter a reversible resting state by activating autophagy-dependent survival mechanisms after imatinib treatment .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10329074	Blue marks normal tissue, red marks tumor tissue, and purple marks metastatic tumor tissue. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Blue", "marks", "normal", "tissue", ",", "r...
PMC11721064	Following euthanasia, all rats were used for skin keratinocytes and corneal epithelial cells isolation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Following", "euthanasia", ",", "all", "rats", "were", "used...
PMC8916024	Four indicator genera were found, namely Flavobacterium, Silanimonas, Geobacter, and Zavarzinella, which were significantly more abundant in the gut of juvenile snails than in the gut of adult snails (P < 0.05, Fig. 3A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	No dose-limiting toxicities (DLTs) were reported and maximum tolerated dose (MTD) was not reached (n=323).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "dose-limiting", ...
PMC8992508	Cytotoxicity data show that their inhibitory effect is substantially higher than their toxicity, and results confirmed that they are able to reverse the BCRP-mediated resistance toward SN-38 and to inhibit the ATPase activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9964635	It is considered an important therapeutic target because of its deregulation of solid tumor types .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "considered", "an", "important", "therapeutic", ...
PMC10748106	Across cultures and civilizations, iridoid-rich plants have been employed for their medicinal properties .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Across", "cultures", "and", "civilizations", ",", "iridoid-rich", "pla...
PMC9429973	E. Tranter, B. Obermayer-Wasserscheid, M.-L. Hütter-Krönke, C. Junkuhn, I.-W. Blau, G. L. Vuong, L. Bullinger, I.-K. Na Department of hematology, oncology and tumor immunology, Charité Universitaetsmedizin Berlin; Berlin Institute of Health (BIH); Core Unit Bioinformatics – CUBI, Berliner Institut für Gesundheitsforsch...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11409031	Following comprehensive quality assessment and clustering for dimensionality reduction, a total of 15 cell clusters were recognized and categorized into eight different cell types, demonstrating substantial diversity across various cell populations (Fig. 1A and B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11798926	Data are represented as mean ± SEM; n = 13–20 cells per group (A); n = 10 cells per group (B); n = 13–16 cells per group (C), each group from 2 to 3 independent experiments; ns not significant; p < 0.05; p < 0.01; p < 0.001; **p < 0.0001.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11672142	The EPR spectra of the pH 2 and 8 species are very similar, revealing a low-spin (S = 1/2) Fe(III) species (Figure S15).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10490530	The obtained results from the co-expression of the above constructs in A2780 and SKOV3 ovarian cancer cells indicated that stabilized p53 transcriptionally down-regulated PIK3CA and attenuated the transcriptional activity of NF-κB. The ChIP assay supported the conclusion drawn based on the results of the triple lucifer...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC10940855	Loss of EPHB1–Ephrin B2 signaling impairs multiple myeloma pathogenesis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Loss", "of", "EPHB1–Ephrin", "B2", "signaling", "impairs", "multiple", "myeloma", "pathogenesis", "." ]...
PMC11687663	Ramachandran plots for all residue types are displayed in Fig 16S in S1 File.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ramachandran", "plots", "for", "all", "residue", "types", "are", ...
PMC11750712	T cell fratricide during manufacture is avoided by depletion of TRBC1 T cells before transduction.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "T", "cell", "fratricide", "during", "manufacture", "is", "a...
PMC11576293	So, from such a perspective, we thought the experimental determination of lipophilicity would give information and a clear idea of the relationship between lipophilicity and antiproliferative activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6600592	Cyclohexyl (E)-4 -methoxyimino-4-(4-chlorophenyl)butanoate (4D-2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cyclohexyl", "(E)-4", "-methoxyimino-4-(4-chlorophenyl)butanoate", "(", "4D-2", ")", "." ] } ]
PMC11297139	Thus, our data indicate that ARID1A builds nuclear condensates via PrLD-induced phase separation and recruits BAF subunits with the aid of Pfam homology domain.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11536589	Images are the removed tumors in the mice that were killed on day 16.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Images", "are", "the", "removed", "tumors", "in", "the", "mice",...

PMC4360730

These slims also allow for a wider exposure and overview of the ENCODE data (https://www.encodeproject.org/help/getting-started#browse).

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PMC11723947

Treg can also act indirectly on T cells, by modulating dendritic cell maturation and function using co-inhibitory receptors such as CTLA-4 or Tim3.

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PMC11543885

This reflects a crucial experiment to investigate the ability of APEX2 labeling to capture changes in the microenvironment of activated versus inactivated NLRP3.

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PMC11013014

Acid 20 (0.59 g, 0.289 mmol), pentafluorophenol (0.58 g, 0.318 mmol), and EDC (0.58 g, 0.318 mmol) are mixed in DMF (5 mL) at 0 °C.

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PMC8623816

Thus, the use of RsRV5 as a biological control agent for rice sheath blight still needs to overcome great difficulties.

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PMC11541241

The target of rapamycin (TOR) was first identified in yeast (Saccharomyces cerevisiae) by screening mutants insensitive to rapamycin (RAP), which is a medicine isolated from the bacterium Streptomyces hygroscopicus and efficiently represses TOR kinase activity (Heitman et al., 1991; Sehgal et al., 1975; Vézina et al., ...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11686380

Cells were then fixed and subjected to immunostaining with anti-GFP and anti-Myc.

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PMC11429241

The experiment was repeated twice.

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "experiment", "was", "repeated", "twice", "." ] } ]

PMC9429973

Human-curated natural language processing with assistance from machine learning algorithms was used to extract EMR data.

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PMC11686380

p < 0.0001 (vs control) by one-way ANOVA and Dunnett’s post hoc test. (

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PMC11786704

Images of skin wounds treated with PBS (control), PC solution and PC capsules in an acute wound model. (

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PMC9429973

Two pts (1R/R and 5R/R) in the R/R cohort experienced PD and subsequently succumbed to lymphoma, both of which harbored TP53 mutations.

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PMC9429973

Aims: The purpose of this study is to examine the effects of macrophage depletion on bone marrow and splenic erythropoiesis under chronic stress conditions.

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PMC11228511

Mean ± SD. ****

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mean", "±", "SD", ".", "*", "*", "*", "*" ] } ]

PMC6889484

Flow cytometry analysis of the transduced cells showed that expression of the A3 (A3dr) or 3G (3Gdr) truncated proteins of A3G-D128K in the lentivector producer cells resulted in <2-fold inhibition of transduction (∼50% and ∼87% eYFP cells compared to cells transduced with eYFPip, respectively).

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PMC11612794

In M phase, the Dsn1 basic motif is precluded from the Nsl1 acidic surface by the CENP-T and Dsn1 dual phosphoregulation.

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PMC11747949

All these proangiogenic and pro‐inflammatory chemokines play a role in osteosarcoma progression.

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PMC8193046

For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)

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PMC9429973

Methods: NGS-based MRD measurements (clonoSEQ) from peripheral blood (PB) at follow-up month 3 were grouped into uMRD <10 (MRD6), 10 ≤ and <10 (MRD4/5), and detectable MRD ≥10 (MRD+).

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PMC11055443

However, it is necessary to further investigate the activation or inhibition of the inflammatory cytokines production and also the signaling pathways involved in Caco-2 cells treated with secretome in future studies.

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PMC10728200

Further studies are needed to fully elucidate the mechanisms underlying the impact of RSL3 on GPX4 mRNA levels and to better understand the intricate regulatory networks involved in ferroptosis.

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PMC9954564

Except for Roas2, they are all expressed in the skin (Human Protein Atlas portal—http://www.proteinatlas.org (accessed on 1 December 2021)).

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PMC11634794

However, overexpression of the LAMP1 gene led to a decrease in the expression of LC3C instead, which was restored upon subsequent knockdown of LAMP1.

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PMC11803918

Upon red light irradiation, hybrid exosomes could produce a large amount of O2 in a time-dependent manner (Figure 5A–C).

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PMC11361748

Briefly, cells were incubated with PLA probes for 1 h at 37°C, with the ligation mixture for 30 min at 37°C, and with the amplification mixture for 100 min at 37°C.

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PMC10998613

In contrast, when CXCR4-VN was coexpressed with CXCR4-VC, the BiFC signal was observed in the plasma membrane and in the cytoplasm.

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PMC11257203

Then, cytochalasin-B (3 μg/mL) was added to the samples, leading to the inhibition of cytokinesis.

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PMC11755467

For annealing, equimolar concentrations of both fragments were incubated at 95 °C for 5 min and allowed to cool to room temperature for at least 1 h. 10 units of T4 dsRNA Ligase 2 (NEB) were then added to the solution and incubated for 1 h at 37 °C.

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PMC9429973

Additionally, HSP-CAR30 has shown promising efficacy in heavily treated HL patients that is being explored in a phase 2 trial already started.

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PMC10955424

Ascites fluid derived from OC patients promoted chemoresistance causing moderate (20 %) and significant (30 %) reduction in cPARP levels as summarized in Fig. 1E.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Results: A total of 158 patients were treated with R-CHOP during the study period but 20 patients were excluded because of poor records (N = 8), planned R-CHOP cycle number other than six (N = 7, e.g., abbreviated cycles plus radiation therapy), and treatment incompletion (N = 5).

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PMC10898159

This mechanism of ETV1 in GIST differs from that in the other ETS-dependent tumors, such as genomic translocation or amplification in prostate cancer .

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PMC9429973

Overall response rate and safety profile were evaluated.

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PMC11650848

When comparing intervention groups for these genotypes against symbol search and cancellation scores there were significant differences through ANOVA analysis.

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PMC11574271

Fig. 7The inhibitory effect of BMS-777607 on RON-mediated activity and the suppressive effect of ectopic expression of miR-659-3p on bladder cancer cells tumorigenic in vivo.

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PMC11745600

To develop a novel therapy for diabetes (particularly through cell transplantation), it is crucial to assess the effectiveness and safety of the cells using diabetic animal models.

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PMC11547972

This theory may explain why amygdalin has been shown to exert synergism under differing conditions, including drugs with different modes of action.

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PMC11394730

Piperine has the potential to increase ROS as well as intracellular calcium levels, which can activate the Fenton reaction and lead to cell death.

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PMC11342785

H, demonstration of the PKA-regulated synMAP circuit design from (G).

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PMC8609870

Gu et al. observed that polymorphisms in lncRNA HULC may be related to the susceptibility to RSA in the Southern Chinese population.

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PMC8584666

GPI-80 belongs to the VNN1/pantetheinase family.

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PMC9429973

CD3+ T-cell proliferation as measured by Ki67 expression and pSYK activation were assessed by quantitative single-cell immunofluorescence microscopy.

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PMC10723784

In addition, carboplatin in combination with 100 nM CBG achieved significantly lower (p < .001) IC50 values of 36.5 ± 3.2 μM, 32.1 ± 2.7 μM, and 29.5 ± 0.5 μM at 48, 72, and 96 h, respectively.

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PMC11721295

To obtain mechanistic insight into fibroblast reprogramming, we subclustered the fibroblast population from the scRNA-seq data set and visualized it by UMAP (Figure 3D).

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PMC11745823

According to experimental needs, the transfected cells were specifically treated to detect the activity of the target regulatory sequence under different conditions.

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PMC9429973

Kaplan-Meier method was used to assess TTP and generate survival curves, with log-rank test for comparison between groups.

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PMC9119314

In addition, 4–6 exhibited potent (nM) activity against T. brucei with good selectivity with respect to Hep G2 cells.

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PMC9429973

Results: A strong positive correlation between elevated levels of CD33CD11bCD14CD15monocytic MDSCs, but not CD33CD11bCD14CD15 granulocytic MDSC and MDR was depicted in non-responder patients compared to responder cohorts.

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PMC9429973

Patients in two groups presented the same overall response rate but a higher possibility of complete remission was observed in allogenic ones.

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PMC10079526

Cells were fixed and immunostained for DNMT1 and DNA double strand break marker γH2Ax.

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PMC9592219

The invasion ability of HCC cells was evaluated by Transwell assay.

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PMC11711127

The phenomena of molecular mimicry as a precedent for some autoimmune diseases may provide contextual evidence for this (2).

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PMC9000591

Among the obtained fractions, SE4 showed the most notable antioxidant activity, followed by SE3.

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PMC7342409

The above-mentioned imatinib-resistant cell lines and GIST882 were inoculated into nude mice to observe their tumorigenicity.

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PMC10671321

The cells were seeded in plates coated with collagen type I. This medium was added at 90% of cell confluence.

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PMC9429973

Summary/Conclusion: Elevated levels of complement biomarkers were associated with a worse TPO-RA treatment response.

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PMC11783017

The data that support the findings of this study are available from the corresponding author upon reasonable request.

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PMC9429973

Median time to count recovery in R/R AML pts was 33 days (range, 24-78).

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PMC11401350

T cells were activated either using anti-CD3 and anti-CD28 antibodies, or IL-7/IL-15 cytokine stimulation for 3 days.

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PMC10568263

The obtained products were collected by centrifugation and washed several times with ethanol and DI water.

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PMC8270637

Subsequently, H9 cells were centrifuged and resuspended in 500 μL of PBS.

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PMC11746948

h Immunoblots of GPX4 and ZDHHC20 in A375 cells infected with lentiviruses encoding empty vector or ZDHHC20.

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PMC9503669

B9 inhibited wild-type HIV-1 replication with an IC50 value in the three-digit nanomolar range in two different cell lines but did not affect replication of Nef-defective HIV-1, supporting a Nef-dependent mechanism of action.

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PMC11754094

= −0.15), resulting in a low correlation with small indels (Pearson corr.

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PMC11513571

All samples were performed in duplicate wells for each stimulant.

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PMC11634794

Nevertheless, at present, we have only preliminarily demonstrated the correlation between LAMP1 and the autophagy-related gene LC3C at the protein expression level.

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PMC11727145

Furthermore, the purpose set forth herein was to simplify the model.

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PMC11740207

This phenomenon has been observed in various malignancies, including gliomas and mammary tumors, where AD helps control MSC populations and contributes to the heterogeneity of the tumor microenvironment (Tassan et al., 2017; Castro-Oropeza et al., 2018; Majumdar and Liu, 2020; Hitomi et al., 2021; Li et al., 2022; Chao...

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PMC11537649

Lnc NEAT1 was knocked down in A375 cells with miR-152-3p inhibitor or CDK6 overexpressing. (

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PMC11377827

The catalytic sites Cys110, His668 and Asn108 are labelled. (

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PMC10882807

Next, the slices were incubated with anti-EIF4A3 (1:100, Proteintech, China) overnight at 4℃ and subsequently with horseradish peroxidase-conjugated anti-mouse/rabbit secondary antibody (1:1000, Changdao Biotechnology, China) for 1 h at room temperature.

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PMC10218459

The cell viability decreased with the increasing duration of treatment with CPP.

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PMC11343332

The results were analyzed by the comparative CT method, and the 2−∆∆CT method was used for the fold change calculation described by Schmittgen and Livak .

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PMC11659734

Nine concentrations of BPE were selected for the chromosome aberration test, based on the results of the in vitro micronucleus test (range from 1.25 to 100 μM).

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PMC9646302

GST-HA-RAC1 and FLAG-LAPTM5 were overexpressed, and the aforementioned protocol was repeated.

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PMC6461034

Second, in a more clinical application, INKA scoring was applied to pTyr‐phosphoproteomic data on patient tumor biopsies (Fig 5C and D).

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PMC11534035

The knockdown group showed 93.04±2.613% of the cells remained vital compared to the control group's 100% (p<0.05).

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PMC6742971

The percentage of specific lysis was calculated as 100 × (experimental – spontaneous release)/(total – spontaneous release).

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PMC11190538

For measurements, the ABTS solution was diluted with ethanol to achieve an absorbance of 0.700 at 734 nm.

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PMC9429973

Results: The median age at treatment was 58 [22-88] years.

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PMC7602170

Gupta and colleagues confirmed that a considerable number of GIST cells enter a reversible resting state by activating autophagy-dependent survival mechanisms after imatinib treatment .

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PMC10329074

Blue marks normal tissue, red marks tumor tissue, and purple marks metastatic tumor tissue. (

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PMC11721064

Following euthanasia, all rats were used for skin keratinocytes and corneal epithelial cells isolation.

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PMC8916024

Four indicator genera were found, namely Flavobacterium, Silanimonas, Geobacter, and Zavarzinella, which were significantly more abundant in the gut of juvenile snails than in the gut of adult snails (P < 0.05, Fig. 3A).

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PMC9429973

No dose-limiting toxicities (DLTs) were reported and maximum tolerated dose (MTD) was not reached (n=323).

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PMC8992508

Cytotoxicity data show that their inhibitory effect is substantially higher than their toxicity, and results confirmed that they are able to reverse the BCRP-mediated resistance toward SN-38 and to inhibit the ATPase activity.

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PMC9964635

It is considered an important therapeutic target because of its deregulation of solid tumor types .

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PMC10748106

Across cultures and civilizations, iridoid-rich plants have been employed for their medicinal properties .

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PMC9429973

E. Tranter, B. Obermayer-Wasserscheid, M.-L. Hütter-Krönke, C. Junkuhn, I.-W. Blau, G. L. Vuong, L. Bullinger, I.-K. Na Department of hematology, oncology and tumor immunology, Charité Universitaetsmedizin Berlin; Berlin Institute of Health (BIH); Core Unit Bioinformatics – CUBI, Berliner Institut für Gesundheitsforsch...

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PMC11409031

Following comprehensive quality assessment and clustering for dimensionality reduction, a total of 15 cell clusters were recognized and categorized into eight different cell types, demonstrating substantial diversity across various cell populations (Fig. 1A and B).

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PMC11798926

Data are represented as mean ± SEM; n = 13–20 cells per group (A); n = 10 cells per group (B); n = 13–16 cells per group (C), each group from 2 to 3 independent experiments; ns not significant; *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.

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PMC11672142

The EPR spectra of the pH 2 and 8 species are very similar, revealing a low-spin (S = 1/2) Fe(III) species (Figure S15).

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PMC10490530

The obtained results from the co-expression of the above constructs in A2780 and SKOV3 ovarian cancer cells indicated that stabilized p53 transcriptionally down-regulated PIK3CA and attenuated the transcriptional activity of NF-κB. The ChIP assay supported the conclusion drawn based on the results of the triple lucifer...

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PMC10940855

Loss of EPHB1–Ephrin B2 signaling impairs multiple myeloma pathogenesis.

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PMC11687663

Ramachandran plots for all residue types are displayed in Fig 16S in S1 File.

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PMC11750712

T cell fratricide during manufacture is avoided by depletion of TRBC1 T cells before transduction.

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PMC11576293

So, from such a perspective, we thought the experimental determination of lipophilicity would give information and a clear idea of the relationship between lipophilicity and antiproliferative activity.

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PMC6600592

Cyclohexyl (E)-4 -methoxyimino-4-(4-chlorophenyl)butanoate (4D-2).

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PMC11297139

Thus, our data indicate that ARID1A builds nuclear condensates via PrLD-induced phase separation and recruits BAF subunits with the aid of Pfam homology domain.

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PMC11536589

Images are the removed tumors in the mice that were killed on day 16.

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