Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
 Community
1
PMCID
string
Sentences
string
ner
list
PMC10840195
Each zebrafish was injected with 150–200 tumour cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "zebrafish", "was", "injected", "with", "150–200", "tumour", "cells", "." ] } ]
PMC11718809
Due to sampling limitations, we selected only two yaks at peak lactation (LP; 120 days postpartum, non-pregnant) and three yaks in the dry period (DP; calved the previous year, non-pregnant) for sampling.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11665584
Next, the expression of these genes during pseudotime in the skin IFE keratinocytes was assessed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Next", ",", "the", "expression", "of", "these", ...
PMC11763533
The angular coefficient is the inclination of the curve, and the higher the coefficient, the higher the inclination and, therefore, the larger the color change per unit of pH. Cells transfected with Amy-luciferase showed a higher angular coefficient (0.28) and greater spectral variation from pH 6.0 to 8.0 (Δλ = 26 nm),...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11509224
The cytotoxic potential of compounds 18 and 19 against A549, MDA-MB-231, human colorectal carcinoma cells (HT-29), and human pancreatic adenocarcinoma cells (PSN1) was evaluated.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7724160
Cells passages for four different time spans (P12, P21, P25 and P37) were analysed in duplicate.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "passages", "for", ...
PMC11740508
The combination was well tolerated at approved doses with either drug in the AML study, perhaps not surprising as myelosuppression is typically not evaluable in AML.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11348300
In all results displayed here, HS values were normalized to their maximum value in each specimen, corresponding to the HS value after the mice were killed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11419566
The use of gene therapy for medical purposes is still fraught with security problems, and it has long been a controversial issue in ethics to prohibit human trials.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11585587
Fig. 8Docking complexes of MAPK1 and RA.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "8Docking", "complexes", "of", "MAPK1", "and", "RA", "." ] } ]
PMC11638255
e Network representation of selected pathways in (d) displaying differentially expressed genes as branches.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "e", "Network", "representation", "of", "selected", "pa...
PMC4270159
Two control and four experimental wells (6 wells total) are needed for each cell line in Cohorts 1–3.i.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Two", "control", "and", ...
PMC11774747
Additionally, expanding these trials to larger cohorts will be essential to fully understand the therapeutic potential and to refine the approach for broader clinical application.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11629461
The above plasmids (pminiSOG PM , pcDNA /NOX5, pminiSOG‐NOX5) and pCMV3‐DUOX2 were sequence verified.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "above", "plasmids", "(", "pminiSOG", ...
PMC9429973
Molecular analysis of the subclones in the diagnostic samples by scNOVA-CITE revealed converging characteristics leading to stem-like phenotypes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Molecular", "analysis", "of", "the", "...
PMC11026382
Thus, even a well-designed catalytically active synthetic enzyme could fail to rescue growth if placed in the wrong cellular context.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "even...
PMC11342785
To determine the relationship between TPPP’s IDRs and its biological activity, we applied three in vitro assays in parallel: 1) a droplet formation assay to determine whether a TPPP construct could phase separate in the presence of crowding reagents; 2) a TIRF-based assay for measuring binding to immobilized single MTs...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11496728
CHO-WT; (B) CHO-KO-1; (C) CHO-KO-2; (D) CHO-KO-3. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CHO-WT", ";", "(", "B", ")", "CHO-KO-1", ...
PMC11539788
UM-UC-3, HEK-293T, and SV-HUC-1 cells were maintained in DMEM (Gibco, USA).
[ { "tags": [ "B-CellLine", "O", "B-CellLine", "I-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "UM-UC-3", ",", "HEK-293",...
PMC9429973
The majority (90.8%) were de novo type and 72.3% had intermediate-risk(IR) cytogenetics, with 88.5% receiving Daunorubicin + Ara-C (DA 7 + 3) induction.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11754432
To investigate the mechanism of how ALOX15B silencing augments keratinocyte inflammation, keratinocytes were treated with the individual components of the cytokine cocktail (Fig. S5).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2118063
Expression of IRF8 transcripts in human tonsillar and PBBs. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Expression", "of", "IRF8", "transcripts", "in", "human", "tonsillar", "and", "PBBs", ".", ...
PMC8358006
The hundreds of whole exomes and genomes of ESCCs have been sequenced in the past few years, and numerous key aberrations have been identified.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11590005
The maximum scores are 63 points in the ‘denial of prejudice’ domain, and 35 points in the ‘affirmation of differences’ domain.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11739696
Level of ROS generation and mitochondrial membrane potential integrity were analyzed using 2,7-Dichlorofluorescein diacetate and 123-Rhodamine dyes, respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Level", "of", "ROS", "generation"...
PMC11711663
Future research should explore radiomics features from multiple modalities, such as CT and MRI, to potentially enhance prediction accuracy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Future", "research", ...
PMC11741906
Results of the pathway analysis indicated that the MAPK signaling pathway may be regulated by miRNAs associated with cisplatin resistance in ovarian cancer.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results...
PMC9429973
OS state consists in an unbalance between the production of reactive oxygen species (ROS) and the ability to neutralize them by antioxidant defenses.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9504875
Furthermore, K63-linked polyubiquitination of RIG-I is inhibited in the presence of N protein.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "K63-linked", "polyubiquitination", "of", "RIG-I", ...
PMC11594641
The mean particle size was comparable between WT and KO A375 sEVs and between WT and KO DMBC12 sEVs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mean", "particle", "size",...
PMC11791432
tumor growth monitored by bioluminescence imaging in NC group and treatment group; (B) Line graph of bioluminescence intensity at different timepoints; (C) KM curves in both groups.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
For safety expansion, patients will receive Ven QD for up to 24 cycles and oral Aza QD on D1-14 of each cycle for up to 24 cycles at the RPTD.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11754436
Quantitative analysis of apoptosis-related protein in MG63 cells, *Represent comparison with the NC group. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Quantitative", "analysis", "of", "apoptosis-re...
PMC11637276
We considered it an on target hit if 2 out of 4 siRNAs reduced or increased Matrigel uptake.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "considered", "it", "an", "on", ...
PMC11762280
Our study demonstrated that ZBP1 was highly expressed in human sun-exposed skin, and ZBP1 knockout reduced keratinocyte death along with the expression of N-GSDMD, cleaved PARP, cleaved caspase-3 and p-MLKL, suggesting that ZBP1 is a key molecule in UVB-induced keratinocyte PANoptosis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9118379
Notably, of the 320 variant PSMs, 149 (46.6%), 62 (19.4%), and 58 (18.1%) PSMs were supported by all three, two, and one OMS tools, respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11576293
Yield 54%; m. p. 258–260°C; H NMR (300 MHz, CDCl3) δ (ppm) = 8.14 (d., 2H, Ar-H, J = 9 Hz), 7.71 (m, 3H, Ar-H and pyrimidine–C5-H), 7.44 (d.d.,
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11723947
This pathogenic immune response can be inhibited by co-injection of large numbers of Treg but at a Treg:Tconv ratio of 2:1 the suppressor cells fail to efficiently repress xenospecific wild-type T cells (Fig. 7d-h).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11055443
In the group of 5 × 10 CFU, V. cholerae had no invasion to the test and control wells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "group", "...
PMC11791478
Tissue factor (TF, also known as thromboplastin, coagulation factor III, or CD142) is a 47-kDa transmembrane glycoprotein that plays an important role in coagulation (1–3).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6461034
Eluting peptides are ionized at a potential of +2 kV and introduced into a Q Exactive mass spectrometer (Thermo Fisher, Bremen, Germany).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8041314
The 2D similarity search was performed by using the MACCS fingerprints as implemented in MOE.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "2D", "similarity", "search", "was", "performed", "by...
PMC11682172
T cell proteome were also analyzed separately and screened for specific T cell markers.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "T", "cell", "proteome", "were", "also", "analyzed", "separately", ...
PMC9243326
According to the species distribution statistics of the NR database, P. canaliculata has the most homologous sequences, revealing that P. canaliculata is closely related to C. chinensis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11001582
In some animals, a silver chloride wire was then attached to a small indentation in the skull overlying cerebellum using cyanoacrylate glue (to act as a ground/reference electrode) and dental cement (Jet) was used to secure the wire and build a well encircling the craniotomy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9512971
Based on the overall balance between the expected time above EC50 and safety risks, 600 mg qid was determined to be an appropriate dose for this study.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11534035
Every primary tumor consists of uniquely mutant cells along with a complex tumor microenvironment and personalizing treatment to individual cancer types, even within one diagnosis, is necessary to optimize therapeutic outcomes and improve patient prognosis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11506670
At 0, 48, and 72 h post-transfection, the number of metabolically active cells in each setup was determined by adding 10 µL of CellTiter 96 Aqueous One-Cell Proliferation Assay Reagent (Cat.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11206502
Because of the growing interest in autophagy induction as a therapeutic approach in bladder carcinoma (BC), we aimed to assess the effects of HB on metabolic phenotype and autophagy levels in 5637 human bladder carcinoma cells (BC).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11635087
Color online) Isolation of chloroplasts from schyzon. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Color", "online", ")", "Isolation", "of", "chloroplasts", "from", "schyzon", ".", "(" ] } ]
PMC11055323
In contrast, SS18-SSX1 has enhanced condensates formation tendency mediated by ICBS mechanism via H2AK119ub histone modification and remodels 3D genome structure (right panel).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9964654
The complex presents a significant ability to inhibit the growth of the Gram-positive bacterium S. aureus Newman (MIC = 15.3 ± 1.3 μg/mL), the yeast Candida glabrata (MIC = 7.0 ± 0.8 µg/mL), and ovarian cancer cells A2780 (IC50 = 0.9 ± 0.2 µM) and A2780cisR (IC50 = 1.7 ± 0.5 µM), which are sensitive and resistant to ci...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10578720
As expected, the expression of SIRT3 (a strong deacetylase) and its interactions with CS and PDHC in macrophages were significantly weakened under HBV stimulation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
S. Aggarwal, S. Kumar, A. Bela, O. Topaloglu Health Economics and Outcomes Research, NOVEL Health Strategies, Chevy Chase; Health Economics and Outcomes Research; Systematic Literature Review Group, NOVEL Health Strategies, Columbia, United States of America Background: Chronic lymphocytic leukemia (CLL) is the most co...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7987994
It has been shown that for obtaining relevant in vitro cytotoxicity results with magnesium-based materials, it is necessary to use up to 10 times more extraction medium than recommended in the standard.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11590005
Given the evidence of racism in the patient-student-professor-institutional system, it is also necessary to understand how modern racism manifests in dental students.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Given",...
PMC11206251
After shaking, the cells were allowed to stand at room temperature for 3 min, and then centrifuged at 4 °C and 12,000 rpm for 15 min.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11190538
On the first day, all yoghurt samples were reviewed and found to be similar in flavor, body and texture, color, and overall acceptance.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11627398
However, this hypothesis needs to be further investigated in future studies.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "this", "hypothesis", "needs", "to", "be", "further", "investigat...
PMC11682525
The hHFSCs were subjected to a hypoxic environment for durations of 24, 48, and 72 hours.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "hHFSCs", "were", "subjected", "...
PMC11545737
In agreement with this finding, Deo and colleagues found that E. coli OMVs triggered caspase-11-dependent cell death of BMDMs .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "agreement", "with", ...
PMC10907726
Osteosarcoma cells were inoculated in a plate (96-wells) (Corning, USA) with 5000 cells per well and cultured in 37 °C cell incubator overnight.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Summary/Conclusion: Treatment with Gilteritinib and Quizartinib as monotherapy is an effective and tolerable option for patients with R/R FLT3-mutated AML in real-life, with similar response rates and toxicity to those reported in Phase 3 trials, despite the fact that the study population from our series was more heter...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3931643
These observations suggest that in isolation, mTOR kinase inhibition and disruption of eIF4F is generally insufficient to kill DLBCLs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "observations", "sug...
PMC11615101
The scores were given on a scale of 1–4: severity, 1: no visible edema, swelling, and redness; 2: moderately involved joints; 3: highly involved joints with edema, redness, and swelling; and 4: joints severely affected by edema, swelling, and redness.41 ELISA was performed (ELK Biotechnology, China), and the levels of ...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11770130
By contrast, the adipocyte-specific Ntsr2 depletion (Adipoq-cre::Ntsr2, referred to Ntsr2 AKO mice) presented the elevation of food intake, but the local treatment of NTS induced remarkable decreases of food intake in an NTSR2-dependent manner.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11721295
Cell lines were tested and selected for subsequent experiments if RAS and p53 were expressed compared with negative control (A549, human KRAS), as seen in Figure 5B.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", ...
PMC11534377
The stable body weight across all groups suggests that the treatments did not induce significant toxicity that affected the overall health of the mice.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11335267
In humans, since the original identification of ALX3 by Twigg et al. as the causative gene for a characteristic form of congenital frontonasal dysplasia, it has been described that this disease can include intellectual disability, ankyloglossia, hearing loss, and agenesis of the corpus callosum.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9412887
Studies have confirmed that hypoxic tumor cells overexpress HIF-1α and P-gp, which observably promote the progress of cancer cells resistant to small-molecule targeted drugs .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11790971
Moreover, pattern recognition techniques have been used to predict performance across different scales by analyzing dynamic behavior over time.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "pattern", ...
PMC11487720
Similarly, six randomly selected WWOXd cells, including MDA-MB-231, NB69, Wwox knockout MEF, L929R, NIH-3T3, and 4T1, were subjected to UV exposure followed by time-lapse microscopy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "B-Cell...
PMC9429973
Patients mostly visited (ie inpatient and outpatient visits, and visits related to diagnostic procedures and treatment) specialist medical practitioners (15.46 [13.73–17.40]), while relatively few visited general medical practitioners (1.72 [1.46–2.02]).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11566417
Angiogenesis assays were conducted using an Abcam angiogenesis kit, per manufacturer’s instructions and as done previously .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Angiogenesis", "assays", "were", "conducted"...
PMC11243198
After fixing the cells, formalin was removed, and 50 μL of PBS added.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "fixing", "the", "cells", ",", "formalin", "was", ...
PMC9429973
Methods: We examined peripheral blood (PB) and bone marrow (BM) samples of 5 AML patients (PTs) relapsing after SCT, and PB of 5 healthy individuals (H), including 2 stem cells donors.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11790971
Five frames were captured and summed for each FOV.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Five", "frames", "were", "captured", "and", "summed", "for", "each", "FOV", "." ] } ]
PMC11482552
Background: Reliable Human Papillomavirus (HPV) testing and genotyping are essential for quality assurance in HPV-based primary screening, disease management and for monitoring the impact of HPV vaccination.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11643491
This solution was added dropwise to 10 mL of an aqueous solution containing 1% PVA while sonicating at 160 watts for 2 min using a probe sonicator (Sonic Rupture 400, OMNI international, Kennesaw, GA, USA), followed by 3 h of stirring for complete evaporation of the organic solvent.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9920575
Thus, the antitumor potential of the Sechium genus is evidenced by another study carried out with a hybrid of S. edule in leukemia cell lines, and the extract showed an antiproliferative and proapoptotic effect with an IC50 lower than 1.3 μg/mL .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11095939
AAV8-TBG-GFP served as negative control.
[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "AAV8-TBG-GFP", "served", "as", "negative", "control", "." ] } ]
PMC11597291
In another study by Vinothini et al. , GO was grafted with methyl acrylate (MA) via in situ atom transfer radical polymerization, in order to create biodegradable GO surfaces for the conjugation of FA and the loading of PCT through π–π stacking interactions (GO-g-MA/FA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11742670
The Framework of the Proposed Model.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "Framework", "of", "the", "Proposed", "Model", "." ] } ]
PMC9429973
Kd values show VIP152 is the most selective CDK9 inhibitor versus all other CDKs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Kd", "values", "show", "VIP152", "is", "the", "most", "selective...
PMC10380508
These findings suggest that higher expression of PAX2 and possibly of PAX8 are associated with better clinical outcomes in RCC.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "findings", "suggest...
PMC9386809
The Roche assay kit has been used for performing MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "Roche", "assay", "kit", "has", "been", "used", ...
PMC11423992
It is one of the most prevalent malignancies worldwide, recognized as a member of the ‘top 10 malignant tumors’, constituting approximately 5% of all cancer cases .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6267596
Together these data suggest that DIAP cells can undergo reductive cell division(s) by multiple different mechanism and may be responsible for therapy failure.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11119602
Whereas parental cells grew as a distinct monolayer, the continuous treatment of HepG2 cells with 8 µM cisplatin for 4 days caused the HepG2/cr cells to cluster and layer up on one another, producing a colony-like phenotype.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "...
PMC9429973
A history of at least one TKI stop was in 29 pts.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "history", "of", "at", "least", "one", "TKI", "stop", "was", "in", ...
PMC10955424
Fatty acids and fatty acids derivatives were found in both types of ascites; however, they were enriched in the malignant ascites.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fatty",...
PMC11394730
Moreover, Anthocyanins have been reported to have a variety of potential anti-tumor effects, which are related to antioxidant, anti-inflammation, anti-mutagenesis, induction of differentiation, inhibition of proliferation through modulation of signal transduction pathways, induction of cell cycle arrest and stimulation...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6268318
Acetone, MeOH, and aqueous extracts of C. quadrangulare were tested for their trypanocidal activity against epimastigotes of Trypanosoma cruzi, the causative agent of Chagas disease.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11772449
The appropriate concentration of SDS-PAGE was selected to separate the protein sample (20–40 μg), and the protein was transferred to the PVDF membrane using the transfer solution (Millipore, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11243198
The 3D structures of BAS 07019774 and GANT61-D were generated using energy minimization in MOE.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "3D", "structures", "of", "BAS", "07019774", ...
PMC11116779
Untreated A549 cells show electron-dense particles and autophagic vacuole (mainly multilamellar bodies), characteristics of adenocarcinoma cells (Figures 6A,B), which was increased in A549 cells treated with PS-NPs 100 μg/mL (Figures 6C,D) or 500 μg/mL (Figures 6E,F) in a concentration-dependent manner.
[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11367146
The (B) (i) Protein-protein interaction (PPI) network analysis between 149 common targets obtained from the STRING database.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC11680562
The CuO NPs' properties were evaluated using various methodologies before their incorporation into the gel.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "CuO", "NPs", "'", "properties", "were", "...
PMC8750422
To evaluate the clinical effect of GPR87 on lung metastasis, we used a xenograft mouse model.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "evaluate", "the", "clinical", "effect", ...
PMC11585254
Mikel Garcia-Marcos (Boston University) and Kirill Martemyanov (University of Florida Scripps) (Masuho et al., 2015).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mikel", "Gar...