Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
 Community
1
PMCID
string
Sentences
string
ner
list
PMC11742231
To accomplish this, the study employs an adaptive fusion module that integrates the two-view features using a control gate weight.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "accomplish", ...
PMC10840195
This study provides an experimental basis for the drug resistance mechanism of RCC to sunitinib.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "study", "provides", "an", "experimental", "basis", ...
PMC9429973
Computational systems biology provides a tool to overcome this challenge.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Computational", "systems", "biology", "provides", "a", "tool", "to", "overcome", "this", "challe...
PMC11720808
The culture medium was changed every two days.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "culture", "medium", "was", "changed", "every", "two", "days", "." ] } ]
PMC11777207
Scale bars, 100 μm in (B) and (D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bars", ",", "100", "μm", "in", "(", "B", ")", "and", ...
PMC9786247
Equal RNA amounts from each sample were reverse transcribed into cDNA, as described previously .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Equal", "RNA", "amounts", "from", "each", "sample", "were",...
PMC10055960
As in compound 8, downfield shifts are observed in the pyridyl doublet signals, supporting the mono-axial site functionalization of the proposed compounds 9 and 10 (Figure 4).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Univariate analysis showed that age ≥60 years (P=0.012), ECOG-PS physical performance 2-4 points (P =0.043), IPI score 3-5 points (P=0.001), β2-Mg elevation(≥5.5 mg/L) (P=0.007), systemic chemotherapy cycles less than 4 times (P<0.001) were the adverse prognostic factors affecting the overall survival of patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10178190
By contrast, combining Crizotinib with HGF (20 ng/mL) abolishes HGF’s effect (Figure 5B).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "By", "contrast", ",", "combining"...
PMC9341513
To see how this large change in 3D structure correlates with gene expression, we performed additional qPCR experiments comparing the expression of the four genes in the locus between the cell lines.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
In addition, we found that OICR-9429 and CX-4945 had a significant synergistic effect on cell proliferation arrest in CEM (Figure 1B) and MOLT4 cells compared with a single drug (P<0.05).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "B-CellLin...
PMC7154001
The generated metabolite profiles, either the types and amounts can be significantly influenced by factors such as species, gender, and route and dose of administration.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8662250
Immunoreactive bands referred to TLR4, angiotensin converting enzyme 2 (ACE‐2), RhoA GTPase, NLRP3, and Caspase‐1 protein expression and (b–f) relative densitometric analysis of each protein (arbitrary units normalized on the expression of the housekeeping protein GAPDH).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11736898
Vitamin D exhibits anti-proliferative and anti-inflammatory properties, suggesting it could have therapeutic utility in keloid disorder.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Vitamin", "D", "exhibits", "anti-proliferative", ...
PMC9429973
Grade ≥3 neutropenia was uncommon.
[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Grade", "≥3", "neutropenia", "was", "uncommon", "." ] } ]
PMC11638255
Tumors were grown for 1 week until tumors reached 8–10 mm (maximal burden: 1500 mm) then treated with saline or TETA for 7 days (400 mg/kg) via oral gavage and tumor kinetics measured as described above followed by tumor collection for flow cytometric analysis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Results: Three groups of patients were identified: homozygous β+ (N=158), compound heterozygous ββ (N=206), and homozygous β0 (N=145).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9065483
Then using the published TFactS tool, we found that the top predicted transcription factor to correlate with this differential gene expression profile was STAT1, confirming our previous and current findings.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9275501
Tumor multidrug resistance (MDR) refers to the phenomenon that tumor cells are resistant to a series of chemotherapy drugs with different structures and mechanisms when they are resistant to a kind of chemotherapeutic drug, which is an important reason for the failure of chemotherapy in clinic (Kunjachan et al., 2013; ...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11594641
Nanoparticle tracking analysis of the small extracellular vesicles was performed using the NanoSight NS3000 instrument (Malvern Instruments, Malvern, UK) with the NTA 3.4 Build 3.4.003 version.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11381192
Tumour microenvironment harbours diverse stress factors that affect the progression of multiple myeloma (MM), and the survival of MM cells heavily relies on crucial stress pathways.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10530622
Thus, inflammation and oxidative stress might be referred as a “common soil” for all abovementioned mechanisms and can also be the cause and/or consequence of oxalate toxicity.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7342409
GIST882: normal control group; GIST882-ir: imatinib-resistant cell lines; GIST882-ir +im: imatinib-resistant cell lines + imatinib; GIST882-ir +CQ: imatinib-resistant cell lines + chloroquine; GIST882-ir +im+ CQ: imatinib-resistant cell lines + imatinib + chloroquine.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8922418
Depending on the phylogenetic analysis of the conserved Cas proteins with comparison of gene repertoires and arrangements in CRISPR-Cas loci, CRISPR-Cas systems can be classified into three distinct types and ten subtypes (Makarova and Koonin, 2015).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11365427
Asparagine, as an intracellular amino acid regulator, is synthesized by asparagine synthetase.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Asparagine", ",", "as", "an", "intracellular", "amino", "acid", ...
PMC11243198
Glioma cell lines T98G and U87MG were plated in 384-well (clear, flat-bottomed) plates in EMEM/10% FBS (50 µL) at densities of 1500 and 2500 cells/well, respectively.
[ { "tags": [ "O", "O", "O", "B-CellLine", "I-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC10898159
SH3BP2 promotes the expression of mutant KIT by up-regulation of the expression of MITF and ETV1.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SH3BP2", "promotes", "the", "expression", "of", "mutan...
PMC8097906
10 nM) treatment compared to the vehicle control (0.1% DMSO).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "10", "nM", ")", "treatment", "compared", "to", "the", "vehicle",...
PMC8382973
The 2P23 gel demonstrated full activity against HIV-1, confirming the effective delivery of the 2P23 peptide in the gel formulation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "2P23", "ge...
PMC9429973
In PEGASUS, 34% (n=27) of patients were on ATT prior to study entry.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "PEGASUS", ",", "34", "%", "(", ...
PMC11026382
The best fit parameters result in a growth rate plateau near 0.9 for the most fit mutant combinations (experimental growth rates between 0.7 and 1.0), but allow resolution of growth rates amongst the least fit mutant combinations (growth rates less that 0.7).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11748363
IR spectra were recorded on a NICOLET 6700 FT‐IR spectrophotometer (Nicolet, Madison, WI, USA) using the ATR‐Ge method.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "IR", ...
PMC9429973
Among the 170 pts with CLL/SLL, the median age was 69 (36-88) years.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Among", "the", "170", "pts", "with", ...
PMC11615101
The graph showing the fold change of TNF-α mRNA expression in different treated groups. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "graph", "showing", "the", "fold", "change", "of", ...
PMC11564322
Stock solutions of the test compounds were prepared in DMSO and were added to RPMI 1640 without phenol red.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Stock", "solutions", "of", "the",...
PMC11507371
Fluorescence (ex/em: 540/590 nm) was measured immediately with a Tecan Infinite M200 Microplate Reader (Tecan group AG, Männedorf, Switzerland).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11791264
To test this idea, we investigated if SETD7 interacted with methylated LC3B in SETD7 OE HEK293T cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O" ], "tokens": [ "To", "test", "this", ...
PMC11794588
Lupeol and cisplatin together had a synergistic impact that in vitro chemosensitized HNSCC cell lines with significant NF-kappaB activity.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lupeol", "and", "cisplatin", "tog...
PMC11549062
The results showed that the expressions of Caspase‐3, PDGFR‐β, PTP1B, and Rab5 were significantly increased in the group of ApoE mice fed with a western diet.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11763111
The RNA sample from two independent replicates of the experiment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "RNA", "sample", "from", "two", "independent", "replicates", "of", "the", "experiment", ...
PMC11514418
Pancreatic cancer is a highly malignant tumor with a rapid progression rate and a high susceptibility to infiltration and metastasis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Pancreatic", "cancer", "is",...
PMC11188874
In the United States, multiple myeloma accounts for 1.8% of new cancer cases and 13% of hematologic cancers (2).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11615218
Some other engineering strategies have focused on restoring activator protein 1 (AP-1) function to prevent T-cell exhaustion by overexpressing the transcription factor c-Jun and the basic leucine zipper ATF-like transcription factor (BATF) .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11574271
Goat anti-MMP12 antibodies were from Abcam.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Goat", "anti-MMP12", "antibodies", "were", "from", "Abcam", "." ] } ]
PMC7057940
A total of 30 metaphases were evaluated for each patient and each cell line.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "total", "of", "30", "metaphases", "were", "evaluated", "for...
PMC9429973
Analyzing the treatment patterns and outcomes for patients with CD30-expressing lymphoma in a real-world setting will bridge the existing knowledge gap.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Analyzing", "the", ...
PMC11750165
To validate their interaction, colocalization assay was performed by cotransfecting their expression constructs into P19 cells and COS cells (Fig. 2).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC5311252
To further evaluate our findings, we selected three oncomotif-miRNA targets (TGFBR2, CDKN1A and E2F1) for western blot validation in four different cell lines (U1810, A549, NCI-H1703 and SK-MES-1) using miR-372-3p mimics.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11720107
Particularly, (+)-catechin , or kaempferol, are well-known full and partial PPARγ agonists, respectively .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Particularly", ",", "(+)-catechin", ",", "or", "kaempf...
PMC10968586
According to further in vitro experimental assays, OLE anti-angiogenetic and lymphangiogenetic action relies on the inhibition of lipid and M2-macrophage accumulation .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "According", ...
PMC11585254
The BRET response between β-arrestin1 or β-arrestin2 and the proximal phospho-site cluster variant showed no change when compared with WT CXCR5 (Fig. 2, B and C), while the BRET response with the medial phospho-site cluster variant was only partially reduced (Fig. 2, B and C).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11682172
Coronin 1A protein fraction levels before and after 72 h incubation with non-targeting siSham or siRNA CORO1A were equally reduced in all three cell lines.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11528603
After 24-hour treatment, total RNA was isolated using Trisure solution (Bioline, UK) according to the instruction of the manufacturer.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After",...
PMC11541241
They revealed that silencing SsTOR retarded the hyphal growth and the formation of sclerotia and compound appressoria of S. sclerotiorum.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "They", "revealed", "that", ...
PMC6379402
The advantage of our methodology is that it is universal and can accommodate single-cell gene expression and other single-cell omics data.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "advantage", ...
PMC11621493
The medium was replaced with fresh DMEM+/+ after 24 h. Cell culture experiments were performed 48 h post transfection.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "medium", "was", "replaced"...
PMC11377827
HeLa or A549 cells were transfected with siRNA SMARTpools for USP43 (Dharmacon, L-023019-00-0005), USP43 siRNA (Eurofins) (5′-GAAGAUGGUUGCAGAGGAA-3′), MISSION siRNA Universal Negative Control (SIC002, Merck), Scrambled negative control (Eurofins): (5′-CAGUCGCGUUUGCGACUGG-3′), or 14-3-3 PAN siRNA (5′-AAGCTGGCCGAGCAGGCTG...
[ { "tags": [ "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC3915447
Synthesis of folate loaded magnetite NPs MNPs (Fe3O4) were prepared by co-precipitation technique, with some modifications in the previously reported method (Karen et al., 1997; Xu and Du, 2003).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11045125
Based on the results obtained with the new model system, we discovered that authentic human BL cell lines, although clearly of GC B cell origin, also express both IGLL1 (a surrogate light chain normally expressed in pre-B cells) and IL7R (an essential survival receptor normally expressed in pro-B cells), and that at le...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11740508
Deficient repair has been successfully exploited therapeutically by inhibition of Poly (ADP-Ribose) Polymerase 1 and 2 (PARP1 and PARP2; review ).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11024707
In a study comparing salivary mi-RNAs obtained from children with ASD, mi-RNA-125b was significantly less expressed in the ASD group compared to controls and correlated with scores on the social subscale of ADOS .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8557138
Transgenic nude mice ubiquitously expressing green fluorescent protein (GFP), were transplanted with red fluorescent protein (RFP) expressing cancer cell lines, for better visualization of cellular interactions between the host and the tumor (Yang et al. 2004).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10745221
DNA and RNA methylation were not explored in this study, but they could be altered as a result of a lower dependence on methionine.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC8753818
After 24 h, cells were exposed to NaBu (11 mM) for 48 h and then they were lysed using lysis buffer (Tris/phosphate 25 mM, Triton X100 1%, Glycerol 10%, DTT 2 mM).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Image: Summary/Conclusion: We here present an academically-developed, IGHV leader-based NGS assay for the detection and quantification of MRD in CLL beyond MRD 10.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9444294
Recently, a rabbit monoclonal antibody was developed and made commercially available, which specifically detects the fusion junction site epitope of SS18-SSX as found in at least 95% of synovial sarcomas.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11730320
Based on the current consesus, reliable detection of CNVs from WES can be accomplished when CNVs span at least three exons, thus this type of deletion would not be reliably detectable either.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11721064
The supernatant was discarded, and the pellet was resuspended in KSFM to obtain a single-cell suspension.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "supernatant", "was", "discarded", ",", ...
PMC9429973
Thus, there remains a substantial unmet need for developing well-tolerated disease-modifying treatments that reduce bone marrow fibrosis to improve haematologic parameters, splenomegaly, symptom burden and quality of life.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11704135
The MIC was determined as the lowest concentration of the pyrimidine derivatives that showed no color change, indicating complete inhibition of growth.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC11040965
Moreover, the exogenous addition of miR29b and the consequent reduction of PI3K/AKT signaling decreased the expression of DNMT3B mRNA (P = 0.0156) and protein (P = 0.0078) (Fig. 3D, E), suggesting a relationship among miR29b, PI3K/AKT pathway and DNMT3B.Fig.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10656496
First three panels include red and green filters while fourth panel is red filter alone to show persistence of SAOS2 growth. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "First", ...
PMC11513011
Ca release can occur through inhibition of calcium re-uptake channels or through disruption of cellular organelles that accumulate Ca, such as endoplasmic reticulum, Golgi apparatus, and lysosomes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2944824
In a p53 reporter gene activity assay, Hr expressing and mock transfected cells displayed increases in luciferase activity after treatment with staurosporine and tunicamycin compared to non treated cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11547972
Nanoencapsulation has been shown to be an innovative technique to enhance drug efficacy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Nanoencapsulation", "has", "been", "shown", "to", "be", "an", "innovative",...
PMC2196094
A cDNA clone encoding the entire coding region of the major rat MC chymase RMCP-1 was isolated (Fig. 2 A, see also Fig. 5 A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6835428
It has been proposed that HGSOC predilection for the omentum is due to cancer cell metabolism, which requires fatty-acid β-oxidation .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "has", "been...
PMC11617590
Mia PaCa‐2 cells were seeded at 5 × 10 cells/mL/well and were treated for 24 h with sulforaphane (SFN) at concentrations of 0, 25, and 100 μM. The Muse Annexin V & Dead Cell Reagent was used to determine apoptosis.
[ { "tags": [ "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11718031
It was found that the use of IS CHO-CD G17.4, IS CHO-CD-17.7, and CD-FortiCHO media led to higher peak cell counts of around 13–14 million cells/mL, compared to only 10 million cells/mL in the control medium CD-CHO.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8978939
Using anti-fibronectin antibody combined with a secondary antibody conjugated with Cy5, matrix deposition by all cell lines was analyzed according to the protocol of Debnath et al. (30).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Extrapolative analysis of allele frequency distribution from all other variants (excl.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Extrapolative", "analysis", "of", "allele", "frequency", "distribution", "from", "all"...
PMC8358006
DNA was bisulfite converted with the EZ DNA Methylation Gold Kit (Zymo Research) for use with the TruSeq library preparation methods.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "DNA", ...
PMC11761919
Additionally, the chemical modification of inulin has been widely studied (Hou et al., 2022; Mi et al., 2021), for example phthaloylated inulin polymer is synthesized through esterification reaction between the functional groups in phthalic anhydride and inulin (Hong et al., 2021).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10671321
There is no evidence that the CTD could be involved in secretion of the hetero-oligomers.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "is", "no", "evidence", "that", "the", "CTD", ...
PMC11697065
Clones expressing high levels of aggregated antibody may experience a growth disadvantage compared to those expressing lower aggregates leading to a skewing of clone selection toward clones with a low aggregation phenotype.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9545714
An illustration describing these two modalities is sketched in Figure 2 below.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", "illustration", "describing", "these", "two", "modalities", "is", "sketched", ...
PMC11323699
After in vivo imaging and mouse euthanasia, subcutaneous tumor or peritoneal tumor mass and metastatic nodules, were collected and imaged with instrument sensitivity set to “Normal” using the same protocol as described above for healthy mice.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11291490
This discrepancy may be attributed to the fact that the inactivated vaccine primarily processes its antigens through the MHC II pathway for presentation to CD4 T cells, thereby assisting B lymphocytes in generating a humoral immune response.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10094712
Therefore, according to the results shown in Figure 4B, there was an increase in the expression of the spliced form of the XBP1s transcription factor.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6835428
Moreover, increased expression level of FR correlates with OC stage, poor response to chemotherapy, and worse survival.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "increased",...
PMC8609870
However, the effects of these treatments are not satisfactory.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "effects", "of", "these", "treatments", "are", "not", "satisfactory", ...
PMC7642379
As expected, the two 293-F lineages (293-F and Freestyle 293-F) showed very similar profiles.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "expected", ",", "the", "two", "293-F"...
PMC7348793
Briefly, unmodified PCR fragments generated with Platinum Superfi DNA polymerase (Thermo Fisher Scientific, Waltham, MA, USA) were gel-purified using the Qiaquick gel extraction kit (Qiagen, Germantown, MD, USA) and ligated into EcoRV-digested pBluescriptII SK+ vector in the presence of an EcoRV enzyme to prevent vecto...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5415764
As expected, PTX+TET/iRGD LPNs presented the highest cytotoxicity against A2780/PTX cells and effectively promoted ROS production, enhanced apoptosis and cell cycle arrests particularly.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC9046263
HML-6 contains an intact open reading frame encoding a small envelope protein, ERVK3-1.
[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HML-6", "contains", "an", "intact", "open", "...
PMC11420784
C, Western blotting of LC3-II in WT, ΔpldA, or ΔpldA+ infected 5637 cells treated with 3-MA.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ "C", ",", "Western", "blo...
PMC10713411
Cell viability of si-NC- or si-TRIB3-transfected A498 cells. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "Cell", "viability", "of", "si-NC-", "or", "si-TRIB3-transfected", "A498", "cells", ".", "(" ] ...
PMC7812570
A Diagram of the lentiviral transfer vector expressing GPI-anchored antibodies.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "Diagram", "of", "the", "lentiviral", "transfer", "vector", "expressing", "GPI-anchored", "a...
PMC9952933
After CAP treatment, growth kinetics and a viability assay were performed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "CAP", "treatment", ",", "growth", "kinetics", "and", "a", "viability", ...
PMC9429973
In 3 months evaluation, 7/10 (70%,2 cases received infusion for less than 3 months) patients in the humanized group maintained in CR, which was higher than the murinized group with CR rate of 5/14 (35.71%). (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...