Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
 Community
1
PMCID
string
Sentences
string
ner
list
PMC11543853
Rhinovirus A and B serotypes are classified into major and minor groups depending on whether they utilize intercellular adhesion molecule 1 or low-density lipoprotein receptor (LDLR) family members for cell entry.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Nine of the cases were studied with OGM (Bionano Genomics).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Nine", "of", "the", "cases", "were", "studied", "with", "OGM", "(", "Biona...
PMC5916734
For all panels, the error bars represent a standard deviation (n=3–4), one representative experiment out of three runs is shown Southern blot analysis of genomic DNA from the 3B12-86 cell line using a probe targeting the FIX ORF sequence revealed one restriction fragment 1921 bps long (Fig. 4C), thus indicating that th...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11387401
For three RNA interactors, we observed significantly impaired HIV-1 infectivity when the SupT1s were pretreated for 48 h with two target-specific ASOs, compared to a condition treated with a scrambled control ASO (Fig. 5A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10507284
Taken together, these above results suggest that TROAP may play a carcinogenic role in STS, leading to poor prognosis in STS patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11544122
These data are consistent with β2AR and AT1AR undergoing β-arrestin-dependent endocytosis, and suggests that CXCR4 uses a β-arrestin-independent mode of endocytosis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "dat...
PMC11541409
Deletion in exon 11 creates a TKD conformation, which permits imatinib entry.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Deletion", "in", "exon", "11", "creates", "a", "TKD", "conformation", ...
PMC9844987
Shown are also the ROC for a decision tree (baseline) model based on CpG content and TBP binding sites alone (average cross validation AUC = 0.68, orange; test set AUC = 0.71, red).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9812014
The alkaloid castanospermine is also an inhibitor of HIV.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "alkaloid", "castanospermine", "is", "also", "an", "inhibitor", "of", "HIV", "." ] } ]
PMC11247842
Interestingly, the SNPs in the GC gene region have trans-effects on expression of several genes on multiple chromosomes in the CattleGTEx .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interestingly", ...
PMC11696659
Luis Paz-Ares reports financial support was provided by Asociación Española contra el Cáncer.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Luis", "Paz-Ares", "reports", "financial", "support", "was", "provided", "b...
PMC9429973
T. Barbui, A. Carobbio, A. Masciulli, A. Iurlo, M. A. Sobas, E. M. Elli, E. Rumi, V. De Stefano, F. Lunghi, M. Marchetti, R. Daffini, M. Gasior Kabat, B. Cuevas, M. L. Fox, M. M. Andrade Campos, F. Palandri, P. Guglielmelli, G. Benevolo, C. Harrison, M. A. Foncillas, M. Bonifacio, A. Alvarez-Larran, J.-J. Kiladjian, E....
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9424261
Similarly, ferroptosis can also be detected by quantifying the content of GSH.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Similarly", ",", "ferroptosis", "can", "also", "be", "detected", "by", ...
PMC10203589
In addition, with the inhibition of FGF18, the expression of c-Jun (effector of MAPK signaling) was also decreased.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "additi...
PMC9024365
Stargazin/TARP-γ2 influences AMPARs through interaction with two distinct protein domains (Tomita et al., 2003, 2005), of which the transmembrane (TM) domains TM3 and TM4 and extracellular loop 2 of stargazin/TARP-γ2 have been found to be critically important (Ben-Yaacov et al., 2017).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11435360
Cell lysate was homogenized, and total RNA was isolated using a QIAshredder and an RNeasy Mini Kit (Qiagen, Toronto, ON, Canada), respectively, and reverse transcribed into cDNA using a OneScript Plus cDNA synthesis Kit (ABM, Milton, ON, Canada) in conjunction with Oligo(dT)12-18 primers.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11052306
On the contrary, dendrimer 2-G3-Cu48 strikingly reduced the caspase-3 content and activity but promoted the translocation of the Bax protein to the mitochondrial compartment, resulting in the release of apoptosis-inducing factor.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11496491
This study calculated the gene number and gene list corresponding to each term through topGO, and further annotated and analyzed the differential genes and GO term.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10547921
Figure 10Design and SAR analysis of Topoisomerase I inhibitors. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Figure", "10Design", "and", "SAR", "analysis", "of", "Topoisomerase", "I", "inhibitors", ".", ...
PMC11787355
Recent studies have employed PTPRZ1 along with other markers to define glioblastoma stem cells (GSC) in single-cell transcriptomic and flow cytometric analyses.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11753949
Cells were plated on 35mm grid, glass-bottom MatTek dishes P35G-1.5–14-CGRD), infected or transfected as indicated, fixed in 2.5% glutaraldehyde in 0.1M cacodylate buffer, and imaged by light microscopy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11392912
The collagen dose was given subcutaneously on the first and fourteenth day through the tail vein and miRNA (Clo-miR-14) treatment was given intraperitoneally (IP) 2 days prior to the induction of CIA and thereafter on every third day till the thirteeth day.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11659734
These preliminary results, obtained in a single experiment, suggest that BPP may induce chromosomal damage in the experimental conditions applied in this study.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC6771295
SIRT1 or SIRT5 silencing in Mero-14 cells did not affect significantly cell viability in the presence of rotenone, etoposide or resveratrol (Figure 1B, compare bars 1–6 to 7–12 and 19–24).
[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11286266
Representative immunoblots from two independent experiments show the expression levels of endogenous KDEL (Lys-Asp-Glu-Leu) receptors in cell lysates from plain CHO-K1 cells, XC45-6S dual unfolded protein response (UPR) reporter cells and a derivative CRTΔ clone (2P).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "B-CellLin...
PMC11451940
The crystal data and structure refinements are summarised in Table S1 in the ESI.‡ In 4, the copper(ii) atom is octahedrally coordinated in a distorted fashion, having an N3O3 donor arrangement, while the zinc(ii) atoms in 5 and 6 are octahedrally bonded, showing the N2O4 donor sets.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11188874
Images were obtained using an Odyssey CLx system for LI-COR applications.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Images", "were", "obtained", "using", "an", "Odyssey", "CLx", "system", "for", "LI-CO...
PMC11402217
C–E) Plate colony formation effects of XD23 and quantitative results in 143B (D) and MG63 cells (E). (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "...
PMC11247842
The second lead SNP, rs208358909, is a synonymous mutation in the STAT6 gene, which is involved in several central pathways of the immune system and in mammary gland development.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11566417
b Representative images of accepted markers for bovine MDEC identification are compared across the four cell line conditions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "b", "Representative", "images", "of", ...
PMC11394730
Resveratrol’s chemical structure consists primarily of two aromatic rings linked by a methylene bridge.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Resveratrol", "’s", "chemical", "structure", "consists", "primari...
PMC9895440
CD nomenclature is used for CD107a (official protein name LAMP1).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CD", "nomenclature", "is", "used", "for", "CD107a", "(", "official", "protein", ...
PMC11286266
However, given their roles in selectively regulating IRE1 signalling (Adamson et al., 2016; Shoulders et al., 2013), we deemed their identification to reflect a bias towards IRE1 activators arising from the selection scheme for ATF6α and IRE1 cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11718031
The impact of various media-feed combinations on viable cell counts and viability is shown in Fig. 3.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "impact", "of", "various", "media-feed", ...
PMC11155445
Complexes were found more potent than acyl thiourea ligands and exhibited considerable activity against HeLa but showed excellent activity against HCT116 and HepG2.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Complex...
PMC10988808
CCDC25 attenuates tumor growth and promotes apoptosis within the tumor tissue.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CCDC25", "attenuates", "tumor", "growth", "and", "promotes", "apoptosis", "within", "the", ...
PMC11224020
Data are representative of two independent experiments (n = 33 cells in 4 µm; n = 43 cells in 3 µm).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11621493
Statistically significant differences are shown as: ∗P < 0.05; ∗∗P < 0.01; and ∗∗∗P < 0.001.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistically", "significant", "differe...
PMC11190062
Cell viability was measured by CellTiter Glo assay after 24 hours.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "viability", "was", "measured", "by", "CellTiter", "Glo", "assay", "after", "2...
PMC11755467
Analysis was performed using GraphPad Prism 8.0 by p value calculation using the Mann–Whitney U test, two-tailed (Enoxacin 50 µM versus DMSO control) while DMSO control = nominator (fold inhibition 1) and fold inhibition = AUC (x) * 100/UC (DMSO control).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9621239
D-F) Average mutation frequency across different fragments within the X gene was assessed via average entropy. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "D-F", ")", "Average", "mutation", "fre...
PMC11695623
Therefore, the low infiltration levels of DC, CD8+ T cells, B cells and NK cells in the high expression group of DCUN1D5 also have implications for our further study.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11320834
The resulting stabilization of the covalent complex turns the normal enzyme into an agent, causing DNA damage .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "resulting", "stabilization", "of", ...
PMC8864075
TWIST1-targeted flavonoid provided a new strategy to inhibit EMT progress for the treatment of NSCLC.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TWIST1-targeted", "flavonoid", "provided", "a", "new", "strategy"...
PMC9429973
To further explore the relevance of TET2 silencing and its potential implications in clonal expansion, preleukemic CD2-Lmo2 mice were sacrificed at different time points (8 and 24 weeks).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11453018
The preferential binding of EWS::FLI1 to GGAA microsatellites creates enhancers that amplify expression of the oncogene, promoting tumor aggression and treatment resistance .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC11763111
The staining procedure for TCF7 was performed as described above, except that tumor cells and PMA stimulation were not included.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "staining", ...
PMC7090062
Membranes were then incubated with horseradish peroxidase (HRP)-conjugated secondary antibodies (all at 1:2000 dilution).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Membranes", "were", "then", "incubated", "with", "hors...
PMC11063646
8011.
[ { "tags": [ "O", "O" ], "tokens": [ "8011", "." ] } ]
PMC11656657
Furthermore, despite many efforts to identify targeted therapies, such as the utilization of tyrosine kinase inhibitors in the treatment of patients with soft-tissue and bone sarcomas, or the administration of intensive chemotherapy and/or radiation, followed by surgical intervention, clinical outcomes have not shown s...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10197932
In contrast, US on myeloid cancer cells have a more pronounced and drastic effect, indeed they undergo complete necrosis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "contrast", ...
PMC11697189
Therefore, in addition to the clinicopathological characteristics, it is imperative to identify prognostic indicators at the gene level, integrate individual differences, and develop new treatment models to improve the overall clinical outcomes of patients in ccRCC.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11087766
The line indicates mean and error bars indicate SD.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "line", "indicates", "mean", "and", "error", "bars", "indicate", "SD", "." ] } ]
PMC11499955
This multiplex approach consists of adding the mixture of the four labelled antibodies on tissue slices (14 μm thick) from mice bearing subcutaneous A431 tumours and quantifying the four released TMPP tags after addition of DBCO.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", ...
PMC6461034
K562 chronic myelogenous leukemia cells with a BCR‐ABL fusion.
[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "K562", "chronic", "myelogenous", "leukemia", "cells", "with", "a", "BCR‐ABL", "fusion", "." ] ...
PMC11323699
Consequently, the median survival significantly increased to 48 days as compared with survival in the control (38 days) and olaparib-resistant mice (41 days).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6102174
Scutellaria baicalensis (Huangqin) is a widely used Chinese herbal medicine in antiinflammatory and anticancer therapy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scutellaria", "baicalensis", "(", "Huangqin", ")"...
PMC11704135
It inhibited the growth of S. epidermidis, S. haemolyticus, and C. albicans at a concentration of 30 mg/mL, while the remaining organisms required a concentration of 60 mg/mL for inhibition.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7709199
The best diffracting crystals were obtained from CSF-1RD1–D3 N240Q expressed in HEK293 GD cells in a condition consisting of 0.2 M lithium sulfate monohydrate, 0.1 M Tris pH 8.5, 28%(w/v) PEG 3350.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11627398
Furthermore, the correlation coefficients between hub genes and TFs were then calculated (S10 Table).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "the", "correlation", "coeffic...
PMC11755519
Classification of extracellular vesicles according to their size and formation mechanism.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Classification", "of", "extracellular", "vesicles", "according", "to", "their", "size", "an...
PMC5963610
Lung metastasis were quantified by weighing the lungs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lung", "metastasis", "were", "quantified", "by", "weighing", "the", "lungs", "." ] } ]
PMC11705862
The sections were incubated for 1 h with blocking solution containing 5% goat serum (Jackson Immunoresearch) and 0.25% Triton X-100 in PBS, and then incubated with rabbit-anti-IRIS-1 or rabbit-anti-IRIS-2 (Capra, #613.610 and #612.609 respectively) together with either chicken-anti-GFAP (1:500, Merck) or Mouse anti-Neu...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11502962
Interactions numbers and interaction weights of cell-to-cell. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interactions", "numbers", "and", "interaction", "weights", "of", "cell-to-cell", ".", "(" ] } ]
PMC8343815
The rate of cell survival was calculated by dividing the absorbance of treated cells to the absorbance of control cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "rate", "of", "c...
PMC11694066
The sample was minced into small pieces that were subsequently digested in 5 mL of Hank’s Balanced Salt Solution buffer with calcium and magnesium (#24020091, Gibco), containing 7.4 mg/mL collagenase type II (#17101-015, Gibco) for 1 hour at 37°C.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11765879
To evaluate the safety of ZSC extract and its selectivity toward cancer cells, the non-cancerous cell line MCF-10A was used as a control.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "token...
PMC11703896
Rapamycin induced cytotoxic effect by promoting apoptosis and autophagy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Rapamycin", "induced", "cytotoxic", "effect", "by", "promoting", "apoptosis", "and", "autophagy", "." ]...
PMC10940855
shRNA-mediated silencing of EPHB4 in BMEC-60 cells reduced the capacity of BMEC-60 cells to support multiple myeloma growth in coculture (Supplementary Fig. S2C and S2D).
[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11224020
Of note, Was-knockout (WASp) DCs exhibited a round morphology, consistent with previous reports by others (Supplementary Video 5).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC8864075
GPI promotes the EMT process of breast cancer cells by inhibiting miR-200 and inducing ZEB1/2 (Teng et al., 2014).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GPI", "promo...
PMC11757230
All data are presented as the mean ± standard deviation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "data", "are", "presented", "as", "the", "mean", "±", "standard", "deviation", "." ...
PMC9429973
The superior clinical outcomes and patient experience with axi-cel over SOC should help inform treatment choices in second-line R/R LBCL for patients ≥65 years.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11655536
The CI value ranged from 0.041 to 1.055 in RPMI-8226 cells and 0.524 to 1.192 in ARH-77 cells, indicating a synergistic anti-proliferative effect for treatment with HA and carfilzomib in most combinations we tested, although in some concentrations the combination presented nearly additive and slightly antagonized effec...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC10170482
We found that F-actin fiber reorganization in soft 3D CS results in higher intracellular fiber tension in comparison with stiff MC conditions (Figure 7E).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9780037
The capacity of cyt c to induce the apoptosis of cancer cells has inspired the development of a diverse set of molecular tools for its delivery and release into the cytoplasm of cancer cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6461034
Tissue was processed as in “Tissue lysate preparation for phosphoproteomics” described below.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tissue", "was", "processed", "as", "in", "“", "Tissue", "lysate"...
PMC5673955
every division cycle, and cells are only able to divide a limited number of times.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "every", "division", "cycle", ",", "and", "cells", ...
PMC11704135
After the incubation period, 10 μl of a 0.5% aqueous solution of triphenyl tetrazolium chloride (TTC) was added to each well, followed by a further incubation of 60 min.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11190238
Although ATP-independent loops are also formed in the absence of cohesin translocation along DNA, it was observed that cohesin-mediated loop formation tends to favor long-range functional interactions between enhancer and their cognate promoters.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11750712
DAPI (blue) is used for nuclear counterstaining.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "DAPI", "(", "blue", ")", "is", "used", "for", "nuclear", "counterstaining", "." ] } ]
PMC10253553
We propose that new therapies that selectively target the kinase that phosphorylates NDRG1 (Thr346) in renal cancer cells might be efficacious in ccRCC.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11222184
Following this, the membranes underwent blocking with 5% skim milk powder in TBST for 1 h. Primary antibodies including anti-HSP27 (1:1000), anti-HSP70 (1:500), anti-HSP90 (1:500) were incubated overnight at 4 °C.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11429241
Consequently, we optimized the seeding density to 14,000 cells per well, which was used next with the different 3D-printed scaffolds described in Section 3.1.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9960565
Then, 0.16 g of G1.5COONa PAMAM (0.06 mmol) was dissolved in 8.5 mL of UPW and subsequently added to the cisplatin solution with a constant mild stirring.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11206251
Significant scientific evidence shows the importance of TCM in the development of new drugs to treat HCC, which is a major disease that threatens human life and health, so research into anti-HCC drugs can’t wait.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11531735
Subsequently, we monitored tumor growth by employing the IVIS imaging system to capture fluorescent signals emanating from the head region of the mice at multiple time points, specifically on Days 3, 7, 10, 15, 17, 21, or 24, until a humane endpoint was reached, and the mice were euthanized via CO2 asphyxiation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8270637
All cell lines were cultured in RPMI 1640 Medium with 10% fetal bovine serum, 100 U/mL penicillin, and 100 μg/mL streptomycin in a humidified atmosphere containing 5% CO2 at 37°C.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11640555
Previous findings also indicate that many anti-cancer drugs reduce inflammation or oxidative stress in cancer cells, pathways that are crucial to be targeted for exerting anti-survival or pro-apoptotic effects .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11098378
Luciferase assays with were performed as described with minor modifications .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Luciferase", "assays", "with", "were", "performed", "as", "described", "with", "minor", "modific...
PMC9429973
It inactivates Bruton’s tyrosine kinase (BTK) by forming a covalent bond in the enzyme catalytic domain at position C481.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "inacti...
PMC9429973
Median age was 51.5 and 49.5 years in the gilteritinib and SC groups, respectively; most pts had not received prior FLT3 inhibitors (87.9% and 93.2%).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11779605
Pemigatinib is also approved for relapsed or refractory myeloid/lymphoid neoplasms with FGFR1 gene rearrangement (34).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Pemigatinib", "is", "also", "approved", "for", ...
PMC11244823
Equid alphaherpesviruses 1 (EHV-1) and 4 (EHV-4) are closely related and both endemic in horses worldwide.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Equid", "alphaherpesviruses", ...
PMC10788478
Guinot et al. analyzed 53 lung cancers for LGR6 expression and found that elevated LGR6 expression was preferentially observed in lung adenocarcinomas at advanced stages, in which the number of Ki‐67‐positive cells was increased.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11185260
BT-12, CHLA-06, and A-204 cells were transfected with scL-SMARCB1 for 24h and treated with increasing concentrations of cisplatin for an additional 72h.
[ { "tags": [ "B-CellLine", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC11543935
Since the measured region was exclusively the ablation area, separated by a biopsy punch, a higher decrease of the cell viability was expected since the field strength of E = 1000 V/cm is stated to lead to irreversible cell damage.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11730000
RA decreased intracellular generation of ROS in CHO-K1 cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "RA", "decreased", "intracellular", "generation", "of", "ROS", "in", "CHO-K1", "cells", "." ] ...
PMC11437637
In the laparotomy group, after surgery, only the counts of total lymphocytes, CD3+, CD4+ T, CD8+ T, and double positive T cells were significantly different from those before surgery (P < 0.05, Table 6).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11772585
HSC-1 and A431 cells in the logarithmic growth phase were transfected with a lentivirus-mediated shRNA targeting human METTL1 (shMETTL1) obtained from Genco Biotechnology (Beijing, China) to knock down METTL1 expression.
[ { "tags": [ "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...