Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
 Community
1
PMCID
string
Sentences
string
ner
list
PMC11683240
The separations were performed at a flow rate of 3 ml/min using the gradient program (min/% B) 0/5, 5/25, 65/55, and 70/80, being A, 0.1% TFA in water, and B, 0.1% TFA in acetonitrile.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11754432
Immunocytochemistry (C) of lysosomal marker LAMP1 (Magenta) and EGFR (Green).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Immunocytochemistry", "(", "C", ")", "of", "lysosomal"...
PMC11701801
Next, the ethanol in the tissue was replaced by xylene, miscible with paraffin.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Next", ",", "the", "ethanol", "in", "the", "tissue", ...
PMC9966931
In addition, we report for the first time a biocatalytic process for the obtention of these bioactive hybrid molecules.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", ...
PMC11366496
p < 0.05, **p < 0.01 and ***p < 0.001.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "p", "<", "0.05", ",", "*", "*", "p", "<", ...
PMC11656380
Next, we explored the role of the cell-penetrating part by replacing the HIV-1 TAT sequence with octa-arginine (R8).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Next", ",", "we",...
PMC10996034
The slivers were dehydrated and sealed with neutral gum.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "slivers", "were", "dehydrated", "and", "sealed", "with", "neutral", "gum", "." ] } ]
PMC9429973
Standard of care treatment includes induction with high-dose methotrexate based chemoimmunotherapy followed by consolidation with autologous stem cell transplant or whole brain radiation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Standar...
PMC9429973
Analysis of the FVIII T1/2 results of 9h~24h, 9h~48h and 24h~48h we found that there were 8 out of 30 cases (26.67%) of T1/2 were basically stable at the same level, while 53.33% (16/30) of the children had significant changes at each time period.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10362265
Because the human tetramer did not have any experimental coordinates, we used an initial MD simulation to relax the constructed human tetramer, which was generated after a symmetry operation of the crystal heterodimer (7al7) and by forming two symmetric disulfide bonds between C74 of hIL18 and C131 of hIL18BP (Fig. S1c...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8427838
The data derived from the Cancer Genome Atlas (TCGA) data set via Kaplan Meier plotter Having observed a correlation between better survival rate and high moesin and ezrin expression levels in human RCC, we asked whether moesin and ezrin mRNA levels are altered in RCC using the same TCGA data set via Fire Brows (http:/...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11726848
Thus, the study of how tumor cells die remains an unsolved task in radiobiology, and it is more advantageous to trigger immunogenic and tolerogenic cell death by the mode of exposure.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11593031
Since its establishment, the cell line has been used for countless studies, such as research into the mechanisms of proliferation and differentiation of neuronal cells, their signaling pathways, and the cytotoxic effects of chemical compounds, drugs, or toxins.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8303372
The time of treatment delivery was chosen as the reference for normalizing each of the curves associated to the experiment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "time", "of", "t...
PMC9429973
These results highlights the importance of finding underlying cause of elevated blood values to reduce risk of recurrent thromboembolic event.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "results", "highligh...
PMC11453018
Fig. 6EWS::FLI1/ regulates LMNB1 and P15 and cellular senescence in ES.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "6EWS::FLI1/", "regulates", "LMNB1", "and", "P15", "and", "cellular", "senescence", ...
PMC11638255
d Representative flow cytometry plots of CD11bLy6G neutrophil frequency of tumors plotted in (c).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "d", "Representative", "flow", "cytometry", "plots...
PMC11604768
GPCRs are present in every cell in the body and are involved in all known biological process from the detection of light in the retina and neurotransmitter relays in the brain to immune cell antigen detection and bone growth.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10376064
The Aβ peptides are produced mainly by β- and γ-secretase cleavage of the β-amyloid-precursor protein (APP) .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "Aβ", "peptides", "are", "produc...
PMC9370419
Then, 38 µL of the reaction reagent, 2 µL of the enzyme mixture, and 0.2 µL of the internal standard were added to 10 µL samples.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9895440
Tumor volume was calculated according to the formula: D/2 x d x d, with D and d being the longest and shortest tumor diameter in mm, respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11594588
These include surgery or trauma, malignancy, prolonged immobilization, pregnancy, congestive heart failure, obesity, advanced age, and a history of venous thrombosis .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4485786
Moreover, the sarcomas did not contain sufficient numbers of CD4 or CD8 T cells to explain cancer control by killing or apoptosis (Fig. S3).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11394227
As caspase is a pivotal factor in signaling during caspase-dependent apoptosis, it is a logical target for anti-apoptotic engineering .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "caspase", "is", ...
PMC11471157
For the rotational culture of mammalian cells, a cell shaker (CS-LR, TAITEC, Tokyo Japan) was employed set to a rotation speed of 50 rpm.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Image: Summary/Conclusion: The results of this analysis indicate that patients with SM-AHN treated with avapritinib in clinical trials had significantly longer OS compared to patients treated with BAT.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11461833
We analysed the datasets with the R package Deseq2.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "analysed", "the", "datasets", "with", "the", "R", "package", "Deseq2", "." ] } ]
PMC11638764
Interestingly, as shown in Figure 1E , p97 expression slightly increased across all three compartments following CB-5083 treatment, with the NER compartment showing the highest log2 fold change of 2.46 (p-value = 0.0018) This may reflect a feedback mechanism in which the inhibition of p97 results in its upregulation as...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11730305
Fig. 10Flow cytometry analysis (a) control and (b) Co3O4@Glu- Ellagic acid NPs treated cancer cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "10Flow", "cytometry", "an...
PMC2118063
These genes include PRDM1 (BLIMP1) (2), a direct target of BCL6, and XBP1 (7), a target of PAX5.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11683130
Pustular psoriasis can be further divided into localized (e.g. palmoplantar pustulosis) and generalized pustular psoriasis (GPP) (14).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Pustula...
PMC11543885
Clustering.i.
[ { "tags": [ "O", "O" ], "tokens": [ "Clustering.i", "." ] } ]
PMC11711663
In our results, we determine that both CVLs are within control since they are less than both RCVL1 and RCVL2, respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC11317131
For each target sequence, twin epegRNA were used (listed on the x-axis).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "each", "target", "sequence", ",", "twin", "epegRNA",...
PMC9429973
A marked decrease of H3K9/27Ac occupancy in the CD9 locus was observed in AML than in ALL cells (4.8-14.2-fold, P<0.05), and strongly correlated with CD9 repression (r=0.585-0.719, P<0.01).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11718809
Four circRNAs were randomly selected for validation, and their primers were designed using the Primer3 Plus Software (v3.3.0) .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Four", "circRNAs", ...
PMC9429973
Furthermore, serum creatinine (sCr) was identified as the key risk factor in non-Hispanic patients, with those having sCr ≥ 1.6 (mg/dL) showing a much smaller chance of improvement (17%) on day 100 post-transplant compared with patients with sCr < 1.6 (79%).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10507284
Excitingly, the external validation results are consistent with previous survival analyses exhibiting that the STS patient with a lower TROAP expression has an improved prognosis (Figures 1J–L).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9884169
Thus, MCT4 was selected, and the GEPIA database revealed 402 bladder cancer patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "MCT4", "was", "selected", ",", "and", "t...
PMC11769516
In addition, it increases oxidative stress reactions, induces apoptosis of neuronal cells and affects the development of the nervous system.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "additi...
PMC10040136
The proportion of MSC was significantly higher in the drug-resistant group compared to the drug-sensitive group (D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "proportion", "of", "MSC", ...
PMC9429973
Aims: The aim of the present study was to evaluate health-related quality of life (HRQOL) of patients under anticoagulant therapy after DVT, PE or AF and to assess convenience and satisfaction of their anticoagulant treatment with vitamin K antagonists.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11496491
The insulin growth factor-like family member (IGFL1), whose expression was verified to be downregulated by PCR, belongs to the IGF-like (IGFL) family.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3203927
Neural basal media, penicillin/streptomycin, L-glutamine, recombinant human leukemia inhibitory factor (hLIF), basic fibroblast growth factor (bFGF), B-27 supplement and phosphate buffered saline (PBS) were obtained from Gibco (Gaithersburg, MD).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11739504
Quantification of the percentage of ciliated cells in Kat2b-depleted cells compared to control shRNA cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Quantification", "of", "the", "percentage", "of", "ciliated", ...
PMC9895440
Statistics are paired-2-way ANOVA with Holm-Sidak correction.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistics", "are", "paired-2-way", "ANOVA", "with", "Holm-Sidak", "correction", "." ] } ]
PMC11621493
The next day, the medium was changed to DMEM +/+.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "next", "day", ",", "the", "medium", "was", "changed", "to", "DMEM",...
PMC10607604
Unlike the 17q LOH, the consequences of which have been largely attributed to the tumor suppressor TP53 located at 17p13, 4q LOH has not been clearly associated with the inactivation of potential tumor suppressor gene(s).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6617630
ChIP assay was performed using the ChIP Assay Kit (EMD Millipore Billerica, MA, USA) with antibodies to BRD4 (Cell Signaling Technology, Cambridge, MA, USA) or IgG following the manufacturer’s instructions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11228511
Lamin C is located at the nuclear rim and in the nucleoplasm. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lamin", "C", "is", "located", "at", "the", "nuclear", "rim", "and", ...
PMC11394227
The ER and the Golgi apparatus are two closely related organelles within the cell, which are involved in synthesizing, processing, and transporting secreted proteins.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Two patients discontinued the study (one withdrew consent, the other due to an AE [silent thyroiditis]).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Two", "patients", ...
PMC11750712
Seventy-two hours after spinoculation, the T cells were harvested and replated in complete R10 media supplemented with 10 ng ml IL-7 (Miltenyi Biotec, 130-095-367) and 10 ng ml IL-15 (Miltenyi Biotec, 130-095- 760).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6450504
The cells were detached on the next day with the aid of enzyme-free cell disassociation buffer (EMD Millipore), washed twice with 2% BSA (w/v) in PBS pH 7.4 containing 0.1% (w/v) sodium azide (staining buffer) and incubated for 45 minutes on ice with phycoerythrin-labeled anti-P-glycoprotein antibody (UIC2, Abcam).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11765678
Membranes were washed 3 × 5 min in 1× tris-buffered saline (TBS; Bio-Rad, Hercules, CA, USA, 1706435) plus 0.1% tween-20 (Sigma, St. Louis, MO, USA, P7949) (TBST).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10243817
By flow cytometric analysis, we consistently found that the frequencies of TGF-βR3 epithelial cells were markedly reduced in eosinophilic CRSwNP compared with other types of CRS and controls (Figure 4D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10958426
In short, the CNV-expression correlation should be a very specific and unique features of gene regulation in cancer cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "short", ",", "th...
PMC11467800
Invasiveness/motility capacity of K562 and K562‐IR cells. (
[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "Invasiveness/motility", "capacity", "of", "K562", "and", "K562‐IR", "cells", ".", "(" ] } ]
PMC9429973
Protein expression was measured using western blot while gene expression was measured using RT-qPCR.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Protein", "expression", "was", "measured", "using", "western", "blot",...
PMC10197932
Briefly, UT and 2T- treated lymphocytes were incubated with Dynabeads for 48 hours and with protein transport inhibitor (4 hours before the analysis), then fixed and stained for surface marker CD8 and intracellular Granzyme B. Figure 7C show that Granzyme B granules formation, after beads stimulation, is similar in bot...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11543885
Figure reprinted with permission from Liang et al. Timing: 2 days Timing: 2 days This section describes the on-beads trypsin digestion of biotinylated proteins from the lysate of flag-NLRP3-APEX2 expressing HEK293 cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4816271
Cytotoxicity was also severely ablated in CID treated cells although some activity was detectable at the highest effector:target ratios.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cytotoxicity", "was", ...
PMC9429973
This is due to the establishment of a quality assurance system, the choice of collection site, the selection of donors and finally the improvement of the quality of screening which has contributed to guaranteeing optimal transfusion safety.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11441402
After a 24-h settling period, each assay was performed and cell density was measured as total number of cells counted (A–B) or absorbance (C–D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11023271
Consistent with our prediction, FAF-BSA failed to down-regulate RIPK4 in either HaCaT or A431 cells (Fig 5D and 5E).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "...
PMC11791432
Low-quality cells were excluded according to the following quality control criteria: 1) On a per sample basis, genes detected in <3 cells were excluded and cells with total genes detected <250 were excluded; 2) When 8 samples were pooled, 500< Cells with total detected genes <6000; 3) Select cells with mitochondrial ex...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10094992
The pellet was diluted in 8 mL of PBS and carefully stratified over 4 mL Ficoll-Paque Plus and then centrifugated at 1800 rpm for 15 min.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11747949
Proteome analysis on 143B cells, harvested from mono‐culture and coculture with healthy donor PBMCs, was performed using Proteome Profiler Human XL Oncology Array Kit (#ARY026, R&D) following manufacturer's instructions.
[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
These improvements were sustained in a long-term extension (LTE, NCT03853798) study that included pts who completed the fixed-dose period of the ACTIVATE study.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10808409
Aliquots of 2 ml were withdrawn at 5, 10, 15, 30, 60, 120, 180, 240, 300, and 360 min, and replaced with equal volumes of fresh release medium.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11723947
n GSEA of genes downregulated in HP1α-deficient vs control Tconv performed using transcriptomes of human Teff and Tex.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "n", "GSEA", "of", "genes", "downregula...
PMC11435360
The primer sequence for -actin was designed using Primer-BLAST software version 1.1.0 (NCI), and primer sequences for CSE, CBS, and 3-MST were designed as previously described (Table 1) .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6450504
Lipid concentration used for each cell line is indicated below each graph and incubation time was 4h.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lipid", "concentration", "used", "for", "each", ...
PMC11411004
In addition, the use of a more diverse cell population is necessary to clarify whether the effect of our strategy in this study is cell specific or universal.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9412887
More importantly, mild hyperthermia could accelerate the binding of Pt to DNA and promote the formation of irreparable crosslinking of Pt-DNA strands, resulting in the destruction of DNA repair.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10747139
Furthermore, 28 moderately induced apoptosis and oxidative stress, while 29 triggered autophagy and mitochondrial membrane-potential depletion.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "28", "moderately", ...
PMC9436459
Albafuran C (50), the first type A-II MDAAs to be reported, was isolated from M. alba by Mitsuo et al. in 1982 , and its C-3" epimer australisine C (55) was obtained from M. australis by Zhang et al. in 2007 .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11422150
In this study, we have yet to provide evidence of the specific target site of hAMSC action, which warrants further investigation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC11144200
Zhuhai, China) and maintained in an SPF environment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Zhuhai", ",", "China", ")", "and", "maintained", "in", "an", "SPF", "environment", "." ...
PMC11615218
Finally, Haradhvala et al. observed that responses to tisa-cel were associated with a striking expansion of CD8 CAR-TCM-like cell populations from the infusion product in LBCL patients .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11697703
This is consistent with our previous results showing upregulation of miR-193b and miR-365 in this condition.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "is", "consistent", "with", "our", "previous", ...
PMC11472639
The effects of exercise on MREM MDSC subsets are presented in Supplementary Table 3.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "effects", "of", "exercise", "on", "MREM", "MDSC", "subset...
PMC11422497
P < 0.05, **P < 0.01, na: no statistical significance.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", "<", "0.05", ",", "*", "*", "P", "<", "0.01...
PMC11541409
A phase IB clinical trial (NCT02164240) (n = 13) was conducted to evaluate the safety and effectiveness of rapid alternation of sunitinib and regorafenib on metastatic and/or unresectable GIST with prior failure to at least imatinib, sunitinib, and regorafenib (fourth-line and beyond), SD was observed in 4 patients, mP...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11792766
HepG2 presented a significant decrease of 46.2% in their mean viability in response to exposure to 0.2% v/v acetic acid, whereas a total loss of viability was observed for Caco‐2 cells at 0.5% v/v acetic acid concentration.
[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10551595
Considering the treatment failure caused by resistance to GCCs and the negative side effects attributed to their high‐dose application, combination therapies with plant‐based drugs have been considered.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10993311
Multiple linear regression analysis showed that maternal DNA methylation was associated with maternal TG and fasting insulin, fetal abdominal circumference, and fetal and neonate HC.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8164677
3D-structures of selected protein targets were retrieved from online protein data bank (http://www.rcsb.org/pdb/home/home.do).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "3D-structures", "of", "selected", "protein", "targets", "were", ...
PMC11015054
To the upper chamber, 100 μL of each cell type was added in serum‐free medium at a concentration ranging from 2 to 3.5 × 10/mL. The lower chamber was filled with medium containing 10% FBS.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11720107
The expression of the studied proteins was determined in cell culture lysates collected in RIPA.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "expression", "of", "the", "studied", "proteins", "wa...
PMC11656657
Indeed, Kaczanowska et al. recently conducted a Phase I trial (NCT02107963) of GD2 CAR T-cells (GD2-CAR.OX40.28.z.iC9), demonstrating the feasibility and safety of the approach in children and young adults with OS and neuroblastoma (NBL).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11578343
To demonstrate that mz‐visco‐NPS is capable of distinguishing different viscoelastic properties, we screened MCF‐7 cells whose cytoskeleton was perturbed with the actin polymerization inhibitor, Latrunculin‐A (Lat‐A) (Figure 2A). ,
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11604768
Four copies of a given binding motif were arranged in six configurations (TRE units) and positioned immediately 5’ to one of three minimal promoters to create short, synthetic promoters (hereafter promoters) driving expression of a protein coding transcript (Luc2) with a barcoded 3’ UTR (Fig. 1, Supplementary Fig. 1).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11224020
These results show that cPLA2 does not accumulate in the nuclei of DCs confined at a height of 2 µm despite their nucleus being extensively stretched.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11285179
The filters were blocked in Tris-buffered saline containing 0.2% Tween plus 5% non-fat milk and incubated with primary antibodies overnight at 4 °C.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11723947
Xenoantigen-activated human CD4 T cells produce large amount of IFN-γ and GM-CSF (Fig. 7d-f), acquire cytotoxic capacity (Fig. 7g), and express T-bet, the master regulator of the Th1 lineage (Fig. 7h).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10988808
A CCDC25 expression indifferent types of cancer was investigated with the TIMER database.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "CCDC25", "expression", "indifferent", "types", "of", "cancer", "was", ...
PMC10380508
Here, we performed real-time quantitative polymerase chain reaction (RT-qPCR) analysis on a series of human RCC cell lines, revealing significant co-expression of PAX2, PAX6, and PAX8.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11457557
And more recently, Genetic wide association studies (GWAS) and epigenetics have been used to identify the susceptible variants or genes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "And", ...
PMC11747949
Again data shows divergent CCR2 antagonist response in hypoxia as compared to normoxia.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Again", "data", "shows", "divergent", "CCR2", "antagonist", "response", "in...