OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC11637276	Consistently, A2780-Rab25 cell migration was impaired upon p38 inhibition or siRNA down-regulation of MAP3K1, MAPK11, PPP2R1A, and α2 integrin (S10A–S10D Fig).	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10197932	Moreover, cancer cells are more susceptible to microtubules and other cytoskeleton components damage caused by ultrasound without affecting healthy cells 57.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", "...
PMC11422150	Macrophages and microglia are pivotal cellular components participating in the inflammatory process, potentially exacerbating secondary SCI and neurological impairment through the secretion of pro-inflammatory cytokines and other harmful substances (Hausmann, 2003).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612626	Peptide peak intensity was ∼2-fold greater in compound A–treated cells than in controls (Fig. 5B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Peptide", "peak", "intensity", "w...
PMC11380454	Figure 9A and Figure S6A show that the treatment of tumor-bearing mice with SAS at 1 or 1.5 mg/kg or with AS101 at all concentrations tested significantly decreased tumor volume.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11400680	To assess the performance of our segmentation model, we calculated the mean IoU, mAP50, and mAP50–95 of all images across the three levels of test sets.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Results: A total of 21 patients were enrolled in the study,12(57.14%) patients with first relapse multiple myeloma.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "A", "t...
PMC11634027	A slight decrease in Ds levels was detected by western blotting when the D motif was deleted, but it was not statistically significant (Fig. 3J,K).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11803918	Surface staining of cells and latex beads was conducted using the following antibodies: anti-CD63 (H2C6), anti-TCR-γδ (B6), anti-MHC-I (W6/32), anti-MHC-II (Tü39), anti-CD86 (GL-1), anti-CCR5 (2D7), anti-NKG2D (1D11), and anti-PD-1 (RUO).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9424261	The following primary antibodies were used for IB: anti-HERPUD1 (1:1000, ab150424, Abcam, Cambridge, UK), anti-GCLC (1:1000, ab190685, Abcam), anti-CBS (1:1000, ab140600, Abcam), anti-CTH (1:1000, ab189916, Abcam), anti-SHMT2 (1:1000, #33443, Cell Signaling Technology (CST), Boston, MA, USA), anti-GSS (1:1000, #ab12481...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4816271	A normal function of the CH2-CH3 region of the Fc region of immunoglobulins is the binding of Fc receptors on immune effector cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", ...
PMC11092382	Additionally, sophocarpine was found to attenuate liver injury in patients with concanavalin A-induced hepatitis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "sophocarpine", "was", "found", "to", "...
PMC9872547	Incubation condition consisted of CO2 (5%) at 37°C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Incubation", "condition", "consisted", "of", "CO2", "(", "5", "%", ")...
PMC11703896	Beevi et al. 2010).	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Beevi", "et", "al.", "2010", ")", "." ] } ]
PMC7136814	All drugs were prepared and stored as per manufacturer indications.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "drugs", "were", "prepared", "and", "stored", "as", "per", "manufacturer", "indications", ...
PMC10878518	Statistical differences in the MFI of CAR and the expression of hTERT mRNA between sarcoma cells and normal fibroblasts were calculated using an unpaired t-test.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11519788	These data indicated that SPOP was a VEZF1 target gene.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "data", "indicated", "that", "SPOP", "was", "a", "VEZF1", "target", "gene", "." ...
PMC11604768	f Example cell line-specific promoters responsive to treatment with 10% FBS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "f", "Example", "cell", "line-specific", "promoters", "responsive", "to", "treatment", ...
PMC11763126	For identification, the peptide samples were dissolved in loading buffer and separated using a nano-flow liquid chromatography system (UltiMate 3000 RSLCnano).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11740508	A–E, G; **, p < 0.0001; , p < 0.001; , p < 0.01; , p < 0.1; ns, not significant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11785489	All human samples analyzed in this study were downloaded from online repositories from prior publications (Table S1), which list demographic characteristics.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC6901583	The Transwell invasion assay involved seeding of 4 × 10 cells suspended in medium lacking serum in the membranes of the upper chamber without/with Matrigel (BD Biosciences) coating.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11337594	Data in A is shown as mean + SEM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "in", "A", "is", "shown", "as", "mean", "+", "SEM", "." ] } ]
PMC11569208	Cells were lysed 24 h later and RNA was extracted.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "lysed", "24", "h", "later", "and", "RNA", "was", "extracted", "." ] ...
PMC11539788	Although the role of RNF19A is poorly understood, the literature has confirmed the dysregulation or dysfunction of RNF19A in various cancers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Although", "...
PMC5574817	The cells were then transferred into a T25 flask containing 5 mL of complete medium and incubated at 37 °C for 48 h. After 48-h maintenance in complete medium without selection antibiotic, both sets of cells (with cDNA clone and blank control) were supplemented with complete medium containing Geneticin in increasing co...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11502327	Lang et al. (41) found that the proliferation rate of Human ovarian cancer A2780 cells line(A2780) and SKOV-3 cells treated with Scutellarein was significantly reduced, and the invasion and migration ability of OC cells were inhibited to the greatest extent when the concentration was 100 μM. In addition, many substance...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "...
PMC11055323	Scale bars, 1 µm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bars", ",", "1", "µm", "." ] } ]
PMC9250505	Animals had free access to food and water at all times.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Animals", "had", "free", "access", "to", "food", "and", "water", "at", "all", "...
PMC11725127	Relative band intensities of USP2 in (G). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Relative", "band", "intensities", "of", "USP2", "in", "(", "G", ")", ".", "(" ] } ]
PMC6684588	P ≤ 0.001 vs. vehicle-injected muscle by one-way ANOVA with Tukey’s adjustment. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", "≤", "0.001", "vs.", "vehicle-injected", "muscle", "by", "on...
PMC9429973	All clinical and laboratory data, prognostic profiling, treatment patterns and responses, adverse events and survival were compiled.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "clinical", "and", ...
PMC11629461	These data suggest that photodynamic action with in‐frame miniSOG activated the in‐frame NOX5, likely via O2 as the reactive intermediate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "data", "...
PMC5963610	Gangliosides are one of the immunosuppressive molecules released by tumors to their microenvironment .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gangliosides", "are", "one", "of", "the", "immunosuppressive", "molecules", ...
PMC10040136	The results show that there is a significant correlation between the results obtained by the two methods (Fig. 2F, G).Fig.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "resul...
PMC9429973	The most frequent toxicity ≥ grade 3 was hematologic, with anemia in 23.8%, thrombocytopenia in 23.8% and neutropenia in 9.5%.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11727638	In conclusion, a 3D lymphoma model was developed by culturing lymphoma-derived TK and KML-1 cells using the on-chip Cell Dome system.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "...
PMC11696659	A, difference between the 99th percentile of the telomere lengths of a sample and the 1st percentile of the telomere lengths of that sample (p < 0.0001).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10578720	Metabolic and immune phenotypes of macrophages were analyzed using metabolomic and flow cytometry techniques.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Metabolic", "and", "immune", "phenotypes", "of", "macrophages", "were"...
PMC11257988	ITC experiments showed that these salt bridge-forming inhibitors bound to both GDP and GTP-bound KRASG12D and effectively disrupted KRAS-CRAF interaction, but did not bind to wild-type or G12C mutant KRAS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10178190	Platinum resistance of OV-90 cells, while not affected by JAK/STAT inhibitors, showed significant apoptosis (high-density cPARP band) in response to Dasatinib in cells exposed to TA HS-5 CM (Figure 4C).	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	PET/CT and cfDNA are complementary increasing SE and SP to predict progression and POD 24 with a high accuracy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PET/CT", "and", "cfDNA", "are", ...
PMC11534035	To support this claim, our research revealed a significant decrease in proliferation, migration, and tumorigenic potential in both the A431 and CAL39 cell lines following treatment with a GPER1 agonist, or a knockdown of PAI1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "...
PMC11106977	BMSCs are a heterogeneous group of multipotent stem cells, including osteochondral and adipocyte progenitors, that exhibit niche forming and immunomodulatory capabilities .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "BMSCs",...
PMC7917457	∗∗∗p < 0.001.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "∗∗∗p", "<", "0.001", "." ] } ]
PMC8633974	The top 35 gRNA candidates were inspected in WebLogo to identify the 8 gRNAs with the highest degrees of conservation among HIV-1 strains.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC7887261	MPZL2 is located at 11q23.3, a known GWAS locus for LC and hearing loss.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MPZL2", "is", "located", "at", "11q23.3", ",", "a", "...
PMC11092382	Antitumor effects of sophocarpine through multiple signaling pathways.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Antitumor", "effects", "of", "sophocarpine", "through", "multiple", "signaling", "pathways", "." ] } ]
PMC11564405	The primary inclusion criteria encompassed: (1) the initial treatment was surgical resection; and (2) the medical records and pathological specimens were complete.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6114978	Approximately 42% of cell lines demonstrated loss of expression of MST1 at the RNA level, while 25% of cell lines demonstrated loss of expression of MST2 at the RNA level (Figure 5A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11473843	Dotplot showing the results of KEGG pathway enrichment analysis of genes that are activated or suppressed in A549 treated with XMD8-92 and Seliciclib in combination (10 µM). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11568601	C TGT-induced cell apoptosis (TUNEL staining, 400×) and enhanced cleaved caspase-3, p-IRE1 and CHOP levels (IHC staining, 400×) in the xenograft model (mean ± SD, n = 3, Scale bar = 20 μm). *	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9424261	The GSH synthesis pathway and the pivotal enzymes required in the synthesis process are shown in Fig. 4C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "GSH", "synthesis", "pathway", "...
PMC11661040	The results showed that knocking down CGREF1 could significantly inhibit tumor growth.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", "showed", "that", "knocking", "down", "CGREF1", "could", "signi...
PMC8609870	But so far, there has been no study on lncRNA-miRNA-AQP1 in RSA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "But", "so", "far", ",", "there", "has", "been", "no", "study", ...
PMC11718817	Cells were used for experiments until passage 20.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "used", "for", "experiments", "until", "passage", "20", "." ] } ]
PMC9412887	A three-dimensional spherical model of multicellular tumor showed that the hypoxic condition was aggravated after treatment with ultrasound alone but relieved when treated with CEPH and ultrasound, indicating that SDT was an oxygen-consuming procedure but PFOB in CEPH could alleviate the hypoxia induced by SDT and enha...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7039683	Motifs shared with zGPAEs are in bold.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Motifs", "shared", "with", "zGPAEs", "are", "in", "bold", "." ] } ]
PMC9429973	Results: Eighty pts were enrolled from 14 centres, with a median follow up of 36 mos (range 24-60).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11637284	Right, combined violin and sina diagrams of DAPI-stained kDNA area measurements, indicated as arbitrary units (a. u.), of the same cell lines but without mini-p166-HA expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11656048	OS has been the most common primary bone malignant tumor in children and adolescents (Wang et al., 2020).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "OS", "has", "been...
PMC11045125	The DNA sequence and EBNA2 protein sequence produced by the CRISPR/CAS9 mutagenesis is shown in Fig 1A.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "DNA", "sequence", "and", "EBNA2", "p...
PMC11700247	This indicates that crossprimed endogenous T cells, induced by RT's crosspresentation, collaborate with CART-19 cells to prevent antigen escape.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "indi...
PMC5417661	As expected, paclitaxel was an effective stabilizer of tubulin polymerization at the 3.0 µM concentration tested.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "expected", ",", "paclitaxel", "was", ...
PMC11742231	Furthermore, Ha extended computational approaches to lncRNA-disease associations by proposing EMFLDA, a matrix factorization method that applies lncRNA expression profiles.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ...
PMC11406030	When cells experience stress, they release nuclear LMTK3 into the cytoplasm, cell membrane, and/or extracellular space.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "When", "cells", "experience", "st...
PMC11738017	Teclistamab and elranatamab are clinically approved anti-BCMA TCEs, and each of them contain a single anti-BCMA binding domain with a reported BCMA affinities (KD) of 0.18 nM and 0.038 nM, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11627060	Fluorescence-activated cell sorting (FACS) was employed for cell cycle analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fluorescence-activated", "cell", "sorting", "(", "FACS", ")", "was", "employed", ...
PMC11684297	The yield percentage was 86.4%.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "yield", "percentage", "was", "86.4", "%", "." ] } ]
PMC11545868	If this gene is not working properly due to a mutation, it will divide indefinitely and progress to cancer .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "If", "this", "gene", "...
PMC11680578	Table 1Combination index (CI) value of paclitaxel (PTX) and rosiglitazone (RGZ).Rosiglitazone (nM)Paclitaxel (nM)CI values50010.11194100010.11320250010.11207500010.0969810,00010.1060625,00010.16282 Combination index (CI) value of paclitaxel (PTX) and rosiglitazone (RGZ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11267830	Samples were resuspended in PI solution (0.05 mg/ml PI, 0.1% sodium citrate, and 0.1% Triton X-100) and incubated at room temperature for 20 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11172027	If one compares the efficiency of NALM in both cell lines, it appears to be the same.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "If", "one", "compares", "the", "effici...
PMC11765678	Combining ferroptosis inducers with chemotherapeutics offers a novel strategy to enhance treatment efficacy and overcome resistance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Combining", "ferroptosis", "inducers", "with", "chemotherape...
PMC9429973	Among these deregulated genes, IKZF1 and its target genes accounted for > 6% of the whole typical expression profile.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Among", "these", ...
PMC11696576	Control samples were spiked at, low, medium, and high concentration levels.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Control", "samples", "were", "spiked", "at", ",", "low", ",", ...
PMC10818573	We used B95-8 cell DNA as the amplification template and performed the RPA reaction for 5, 10, 15, or 20 min.	[ { "tags": [ "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC11786767	To further confirm the role of Ki-67 in controlling lipid distribution across chromosomes and the perichromosomal layer, we studied the effect of Ki-67 knockdown in COS-7 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellL...
PMC11544122	Data represent the mean ± SEM from five to ten independent experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "represent", "the", "mean", "±", "SEM", "from", "five", "to", "ten"...
PMC11680049	Further studies focused on exploring the localization characteristics of active secondary metabolites—specifically, polyphenolic and terpenoid compounds—which are integral to understanding the physiological and biochemical status of callus and suspension cultures influenced by various factors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11738017	Box plot comparing the PFS of patients with or without antigen loss at relapse. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Box", "plot", "comparing", "the", "PFS", "of", "patients", ...
PMC11267036	Meanwhile, DHM notably elevated E-cadherin expression and reduced N-cadherin expression in xenograft mice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Meanwhile", ",", "DHM", "notably", "elevated", "E-cadherin", "expressi...
PMC9325715	The calculated values indicate that the majority of iron should bond loosely to the protein and do not induce the formation of new metal-binding sites.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9325715	In the case of Ova-albumin, the relatively high Langmuir constant can be explained by the formation of Zn/ZnO nanoparticles.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "case", "o...
PMC11453018	Notably, iP300w displayed superior efficacy against CIC::DUX4 sarcoma compared to A-485 , another P300/CBP inhibitor from the same spirocyclic chemical series found to be effective against certain hematological malignancies, androgen receptor-positive prostate cancer, and NUT midline carcinoma .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11371747	Influx competition profiles, at 5 µM [H]-l-LV extracellular concentrations, are shown in Figure 3A.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Influx", "competition", "profiles", ",", "at", "5", ...
PMC11291490	Attenuated vaccines pose the risk of virulence regression and may create new strains.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Attenuated", "vaccines", "pose", "the", "risk", "of", "virulence", "regress...
PMC10818573	To determine which of the newly added components affected the normal reaction, different templates (ddH2O, HeLa DNA, and B95-8 DNA) were chosen to validate the initial RPA system.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine"...
PMC9429973	For 3 patients (7%), the treatment was watchful waiting.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "3", "patients", "(", "7", "%", ")", ",", "the", "treatme...
PMC11707577	3D spheroids were generated through the hanging drop method.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "3D", "spheroids", "were", "generated", "through", "the", "hanging", "drop", "method", "." ] } ]
PMC11576293	Moreover, assessment of the bioactivity score (F) of the new compounds using Swiss ADMET showed their substantial bioavailability (score above zero) and hence a higher probability of medicinal impact and biological activities in clinical trials.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11551844	AuNPs-contignasterol displayed lower activity than contignasterol in the A172 cell line.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "AuNPs-contignasterol", "displayed", "lower", "activity", "than", "contignasterol", "in", ...
PMC7351993	In fact, SIP has been used to overcome difficulties of fluorescent probes (which are bulky and perturbative for metabolites), fluorescent fusion proteins (which are not available to all types of biomolecules and cells), and mass spectrometry (which only gives the average metabolic information of many cells and cannot b...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8382973	Due to the rectovaginal application of the 2P23 gel, no significant change in Shannon alpha diversity of the rectal or vaginal microbiota was observed (Figure 9A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Progression-free survival (PFS) and overall survival (OS) rates at 1 year were 77% and 89%, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Progres...
PMC11489351	D, quantification of immunoblots prepared as in (C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "D", ",", "quantification", "of", "immunoblots", "prepared", "as", "in", "(", "C", ...
PMC4485648	The expansive tumor growth then leads to architectural and physiological changes in the tumor tissue microenvironment, including a reduced oxygen delivery by the aberrant vasculature.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10547921	It showed weaker inhibitory activity on tubulin polymerization than maytansine, implying that the ester moiety at the C3 position of maytansine and maytansinoids plays an important role in biological activity and cell permeability.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11758416	Be sure to plate excess wells of T cells if T cell death following stimulation is expected, see problem 2 below.i.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Be", "sure",...
PMC9429973	Findings for transferrin saturation were similar.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Findings", "for", "transferrin", "saturation", "were", "similar", "." ] } ]

PMC11637276

Consistently, A2780-Rab25 cell migration was impaired upon p38 inhibition or siRNA down-regulation of MAP3K1, MAPK11, PPP2R1A, and α2 integrin (S10A–S10D Fig).

[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10197932

Moreover, cancer cells are more susceptible to microtubules and other cytoskeleton components damage caused by ultrasound without affecting healthy cells 57.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", "...

PMC11422150

Macrophages and microglia are pivotal cellular components participating in the inflammatory process, potentially exacerbating secondary SCI and neurological impairment through the secretion of pro-inflammatory cytokines and other harmful substances (Hausmann, 2003).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11612626

Peptide peak intensity was ∼2-fold greater in compound A–treated cells than in controls (Fig. 5B).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Peptide", "peak", "intensity", "w...

PMC11380454

Figure 9A and Figure S6A show that the treatment of tumor-bearing mice with SAS at 1 or 1.5 mg/kg or with AS101 at all concentrations tested significantly decreased tumor volume.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11400680

To assess the performance of our segmentation model, we calculated the mean IoU, mAP50, and mAP50–95 of all images across the three levels of test sets.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Results: A total of 21 patients were enrolled in the study,12(57.14%) patients with first relapse multiple myeloma.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "A", "t...

PMC11634027

A slight decrease in Ds levels was detected by western blotting when the D motif was deleted, but it was not statistically significant (Fig. 3J,K).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11803918

Surface staining of cells and latex beads was conducted using the following antibodies: anti-CD63 (H2C6), anti-TCR-γδ (B6), anti-MHC-I (W6/32), anti-MHC-II (Tü39), anti-CD86 (GL-1), anti-CCR5 (2D7), anti-NKG2D (1D11), and anti-PD-1 (RUO).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9424261

The following primary antibodies were used for IB: anti-HERPUD1 (1:1000, ab150424, Abcam, Cambridge, UK), anti-GCLC (1:1000, ab190685, Abcam), anti-CBS (1:1000, ab140600, Abcam), anti-CTH (1:1000, ab189916, Abcam), anti-SHMT2 (1:1000, #33443, Cell Signaling Technology (CST), Boston, MA, USA), anti-GSS (1:1000, #ab12481...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC4816271

A normal function of the CH2-CH3 region of the Fc region of immunoglobulins is the binding of Fc receptors on immune effector cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", ...

PMC11092382

Additionally, sophocarpine was found to attenuate liver injury in patients with concanavalin A-induced hepatitis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "sophocarpine", "was", "found", "to", "...

PMC9872547

Incubation condition consisted of CO2 (5%) at 37°C.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Incubation", "condition", "consisted", "of", "CO2", "(", "5", "%", ")...

PMC11703896

Beevi et al. 2010).

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Beevi", "et", "al.", "2010", ")", "." ] } ]

PMC7136814

All drugs were prepared and stored as per manufacturer indications.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "drugs", "were", "prepared", "and", "stored", "as", "per", "manufacturer", "indications", ...

PMC10878518

Statistical differences in the MFI of CAR and the expression of hTERT mRNA between sarcoma cells and normal fibroblasts were calculated using an unpaired t-test.

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PMC11519788

These data indicated that SPOP was a VEZF1 target gene.

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PMC11604768

f Example cell line-specific promoters responsive to treatment with 10% FBS.

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PMC11763126

For identification, the peptide samples were dissolved in loading buffer and separated using a nano-flow liquid chromatography system (UltiMate 3000 RSLCnano).

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PMC11740508

A–E, G; ****, p < 0.0001; ***, p < 0.001; **, p < 0.01; *, p < 0.1; ns, not significant.

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PMC11785489

All human samples analyzed in this study were downloaded from online repositories from prior publications (Table S1), which list demographic characteristics.

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PMC6901583

The Transwell invasion assay involved seeding of 4 × 10 cells suspended in medium lacking serum in the membranes of the upper chamber without/with Matrigel (BD Biosciences) coating.

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PMC11337594

Data in A is shown as mean + SEM.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "in", "A", "is", "shown", "as", "mean", "+", "SEM", "." ] } ]

PMC11569208

Cells were lysed 24 h later and RNA was extracted.

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PMC11539788

Although the role of RNF19A is poorly understood, the literature has confirmed the dysregulation or dysfunction of RNF19A in various cancers.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Although", "...

PMC5574817

The cells were then transferred into a T25 flask containing 5 mL of complete medium and incubated at 37 °C for 48 h. After 48-h maintenance in complete medium without selection antibiotic, both sets of cells (with cDNA clone and blank control) were supplemented with complete medium containing Geneticin in increasing co...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11502327

Lang et al. (41) found that the proliferation rate of Human ovarian cancer A2780 cells line(A2780) and SKOV-3 cells treated with Scutellarein was significantly reduced, and the invasion and migration ability of OC cells were inhibited to the greatest extent when the concentration was 100 μM. In addition, many substance...

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PMC11055323

Scale bars, 1 µm.

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bars", ",", "1", "µm", "." ] } ]

PMC9250505

Animals had free access to food and water at all times.

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PMC11725127

Relative band intensities of USP2 in (G). (

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PMC6684588

P ≤ 0.001 vs. vehicle-injected muscle by one-way ANOVA with Tukey’s adjustment. (

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PMC9429973

All clinical and laboratory data, prognostic profiling, treatment patterns and responses, adverse events and survival were compiled.

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PMC11629461

These data suggest that photodynamic action with in‐frame miniSOG activated the in‐frame NOX5, likely via O2 as the reactive intermediate.

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PMC5963610

Gangliosides are one of the immunosuppressive molecules released by tumors to their microenvironment .

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PMC10040136

The results show that there is a significant correlation between the results obtained by the two methods (Fig. 2F, G).Fig.

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PMC9429973

The most frequent toxicity ≥ grade 3 was hematologic, with anemia in 23.8%, thrombocytopenia in 23.8% and neutropenia in 9.5%.

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PMC11727638

In conclusion, a 3D lymphoma model was developed by culturing lymphoma-derived TK and KML-1 cells using the on-chip Cell Dome system.

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PMC11696659

A, difference between the 99th percentile of the telomere lengths of a sample and the 1st percentile of the telomere lengths of that sample (p < 0.0001).

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PMC10578720

Metabolic and immune phenotypes of macrophages were analyzed using metabolomic and flow cytometry techniques.

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PMC11257988

ITC experiments showed that these salt bridge-forming inhibitors bound to both GDP and GTP-bound KRASG12D and effectively disrupted KRAS-CRAF interaction, but did not bind to wild-type or G12C mutant KRAS.

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PMC10178190

Platinum resistance of OV-90 cells, while not affected by JAK/STAT inhibitors, showed significant apoptosis (high-density cPARP band) in response to Dasatinib in cells exposed to TA HS-5 CM (Figure 4C).

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PMC9429973

PET/CT and cfDNA are complementary increasing SE and SP to predict progression and POD 24 with a high accuracy.

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PMC11534035

To support this claim, our research revealed a significant decrease in proliferation, migration, and tumorigenic potential in both the A431 and CAL39 cell lines following treatment with a GPER1 agonist, or a knockdown of PAI1.

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PMC11106977

BMSCs are a heterogeneous group of multipotent stem cells, including osteochondral and adipocyte progenitors, that exhibit niche forming and immunomodulatory capabilities .

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PMC7917457

∗∗∗p < 0.001.

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PMC8633974

The top 35 gRNA candidates were inspected in WebLogo to identify the 8 gRNAs with the highest degrees of conservation among HIV-1 strains.

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PMC7887261

MPZL2 is located at 11q23.3, a known GWAS locus for LC and hearing loss.

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PMC11092382

Antitumor effects of sophocarpine through multiple signaling pathways.

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PMC11564405

The primary inclusion criteria encompassed: (1) the initial treatment was surgical resection; and (2) the medical records and pathological specimens were complete.

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PMC6114978

Approximately 42% of cell lines demonstrated loss of expression of MST1 at the RNA level, while 25% of cell lines demonstrated loss of expression of MST2 at the RNA level (Figure 5A).

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PMC11473843

Dotplot showing the results of KEGG pathway enrichment analysis of genes that are activated or suppressed in A549 treated with XMD8-92 and Seliciclib in combination (10 µM). (

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PMC11568601

C TGT-induced cell apoptosis (TUNEL staining, 400×) and enhanced cleaved caspase-3, p-IRE1 and CHOP levels (IHC staining, 400×) in the xenograft model (mean ± SD, n = 3, Scale bar = 20 μm). *

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PMC9424261

The GSH synthesis pathway and the pivotal enzymes required in the synthesis process are shown in Fig. 4C.

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PMC11661040

The results showed that knocking down CGREF1 could significantly inhibit tumor growth.

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PMC8609870

But so far, there has been no study on lncRNA-miRNA-AQP1 in RSA.

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PMC11718817

Cells were used for experiments until passage 20.

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PMC9412887

A three-dimensional spherical model of multicellular tumor showed that the hypoxic condition was aggravated after treatment with ultrasound alone but relieved when treated with CEPH and ultrasound, indicating that SDT was an oxygen-consuming procedure but PFOB in CEPH could alleviate the hypoxia induced by SDT and enha...

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PMC7039683

Motifs shared with zGPAEs are in bold.

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PMC9429973

Results: Eighty pts were enrolled from 14 centres, with a median follow up of 36 mos (range 24-60).

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PMC11637284

Right, combined violin and sina diagrams of DAPI-stained kDNA area measurements, indicated as arbitrary units (a. u.), of the same cell lines but without mini-p166-HA expression.

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PMC11656048

OS has been the most common primary bone malignant tumor in children and adolescents (Wang et al., 2020).

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PMC11045125

The DNA sequence and EBNA2 protein sequence produced by the CRISPR/CAS9 mutagenesis is shown in Fig 1A.

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PMC11700247

This indicates that crossprimed endogenous T cells, induced by RT's crosspresentation, collaborate with CART-19 cells to prevent antigen escape.

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PMC5417661

As expected, paclitaxel was an effective stabilizer of tubulin polymerization at the 3.0 µM concentration tested.

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PMC11742231

Furthermore, Ha extended computational approaches to lncRNA-disease associations by proposing EMFLDA, a matrix factorization method that applies lncRNA expression profiles.

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PMC11406030

When cells experience stress, they release nuclear LMTK3 into the cytoplasm, cell membrane, and/or extracellular space.

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PMC11738017

Teclistamab and elranatamab are clinically approved anti-BCMA TCEs, and each of them contain a single anti-BCMA binding domain with a reported BCMA affinities (KD) of 0.18 nM and 0.038 nM, respectively.

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PMC11627060

Fluorescence-activated cell sorting (FACS) was employed for cell cycle analysis.

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PMC11684297

The yield percentage was 86.4%.

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PMC11545868

If this gene is not working properly due to a mutation, it will divide indefinitely and progress to cancer .

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PMC11680578

Table 1Combination index (CI) value of paclitaxel (PTX) and rosiglitazone (RGZ).Rosiglitazone (nM)Paclitaxel (nM)CI values50010.11194100010.11320250010.11207500010.0969810,00010.1060625,00010.16282 Combination index (CI) value of paclitaxel (PTX) and rosiglitazone (RGZ).

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PMC11267830

Samples were resuspended in PI solution (0.05 mg/ml PI, 0.1% sodium citrate, and 0.1% Triton X-100) and incubated at room temperature for 20 min.

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PMC11172027

If one compares the efficiency of NALM in both cell lines, it appears to be the same.

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PMC11765678

Combining ferroptosis inducers with chemotherapeutics offers a novel strategy to enhance treatment efficacy and overcome resistance.

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PMC9429973

Among these deregulated genes, IKZF1 and its target genes accounted for > 6% of the whole typical expression profile.

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PMC11696576

Control samples were spiked at, low, medium, and high concentration levels.

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PMC10818573

We used B95-8 cell DNA as the amplification template and performed the RPA reaction for 5, 10, 15, or 20 min.

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PMC11786767

To further confirm the role of Ki-67 in controlling lipid distribution across chromosomes and the perichromosomal layer, we studied the effect of Ki-67 knockdown in COS-7 cells.

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PMC11544122

Data represent the mean ± SEM from five to ten independent experiments.

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PMC11680049

Further studies focused on exploring the localization characteristics of active secondary metabolites—specifically, polyphenolic and terpenoid compounds—which are integral to understanding the physiological and biochemical status of callus and suspension cultures influenced by various factors.

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PMC11738017

Box plot comparing the PFS of patients with or without antigen loss at relapse. (

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PMC11267036

Meanwhile, DHM notably elevated E-cadherin expression and reduced N-cadherin expression in xenograft mice.

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PMC9325715

The calculated values indicate that the majority of iron should bond loosely to the protein and do not induce the formation of new metal-binding sites.

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PMC9325715

In the case of Ova-albumin, the relatively high Langmuir constant can be explained by the formation of Zn/ZnO nanoparticles.

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PMC11453018

Notably, iP300w displayed superior efficacy against CIC::DUX4 sarcoma compared to A-485 , another P300/CBP inhibitor from the same spirocyclic chemical series found to be effective against certain hematological malignancies, androgen receptor-positive prostate cancer, and NUT midline carcinoma .

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PMC11371747

Influx competition profiles, at 5 µM [H]-l-LV extracellular concentrations, are shown in Figure 3A.

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PMC11291490

Attenuated vaccines pose the risk of virulence regression and may create new strains.

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PMC10818573

To determine which of the newly added components affected the normal reaction, different templates (ddH2O, HeLa DNA, and B95-8 DNA) were chosen to validate the initial RPA system.

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PMC9429973

For 3 patients (7%), the treatment was watchful waiting.

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PMC11707577

3D spheroids were generated through the hanging drop method.

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PMC11576293

Moreover, assessment of the bioactivity score (F) of the new compounds using Swiss ADMET showed their substantial bioavailability (score above zero) and hence a higher probability of medicinal impact and biological activities in clinical trials.

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PMC11551844

AuNPs-contignasterol displayed lower activity than contignasterol in the A172 cell line.

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PMC7351993

In fact, SIP has been used to overcome difficulties of fluorescent probes (which are bulky and perturbative for metabolites), fluorescent fusion proteins (which are not available to all types of biomolecules and cells), and mass spectrometry (which only gives the average metabolic information of many cells and cannot b...

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PMC8382973

Due to the rectovaginal application of the 2P23 gel, no significant change in Shannon alpha diversity of the rectal or vaginal microbiota was observed (Figure 9A).

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PMC9429973

Progression-free survival (PFS) and overall survival (OS) rates at 1 year were 77% and 89%, respectively.

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PMC11489351

D, quantification of immunoblots prepared as in (C).

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PMC4485648

The expansive tumor growth then leads to architectural and physiological changes in the tumor tissue microenvironment, including a reduced oxygen delivery by the aberrant vasculature.

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PMC10547921

It showed weaker inhibitory activity on tubulin polymerization than maytansine, implying that the ester moiety at the C3 position of maytansine and maytansinoids plays an important role in biological activity and cell permeability.

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PMC11758416

Be sure to plate excess wells of T cells if T cell death following stimulation is expected, see problem 2 below.i.

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PMC9429973

Findings for transferrin saturation were similar.

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