OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC9545714	Some of these supplements have demonstrated health benefits, while the effects of others are controversial.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Some", "of", "these", "supplements", "have", "demonstr...
PMC10073922	Despite the tumor specificity of various TSPs, low transcriptional efficiency usually hinders their utilization for gene therapy strategies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Despite", "the", "tumor", "specif...
PMC11752740	The MTT assay revealed IC50 values of 2.014 mg/mL and 1.031 mg/mL in the SK-BR3 cell line, and 3.265 mg/mL and 2.994 mg/mL in the MCF10A cell line at 24- and 48-hours post-treatment with Pistachio hull extract.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11718109	Scale bars, 10 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bars", ",", "10", "μm", "." ] } ]
PMC10114490	Lentivirus was collected and concentrated using Lenti-X concentrator following manufacturer´s instructions (Takara).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lentivirus", "was", "collected", "and", "concentrated", "using", "Lent...
PMC11779960	Additionally, we have recently published early data from an ongoing phase I/II clinical study evaluating TRBC1 targeted autologous chimeric antigen receptor (CAR) T cells (NCT03590574) in patients with relapsed/refractory TRBC1 T cell lymphoma.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11792740	Targeting these factors offers a promising strategy to reverse exhaustion and restore T-cell functionality.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Targeting", "these", "factors", "offers", "a", "promising", "strategy"...
PMC9019892	Imatinib, nintedanib and sunitinib were dissolved in 0.5% Methylcellulose and 0.4% Tween 80 solution.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Imatinib", ",", "nintedanib", "and", "sunitinib",...
PMC11790599	The scale bar is 500 nm. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "scale", "bar", "is", "500", "nm", ".", "(" ] } ]
PMC6222635	In the HSQC spectrum, we also found the signals (93.58, 5.10) and (99.03, 4.87).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "HSQC...
PMC11597167	Overall, these results highlight the potential of certain phenolic compounds, particularly quercetin, EGCG, and rosmarinic acid, as promising BACE1 inhibitors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	Long-term persistence of WU-NK-101 and anti-THP-1 efficacy could be further enhanced upon repeated dosing and using fluorescently labeled WU-NK-101 cells, homing and penetration into the BM was observed.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "...
PMC11629461	Technologies for spatially and temporally controlled activation of NOX are, however, not readily available.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Technologies", "for", "spatially", "and", "temporally", ...
PMC11322866	The results showed that compared with the control group, GSK126-treated cells had a higher level of p21 ( Figure 1B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "resul...
PMC9429973	Median follow-up was 12 months (8.7-15.1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Median", "follow-up", "was", "12", "months", "(", "8.7", "-", "15.1", ")", "." ] } ]
PMC7090062	Statistical analysis was performed by one-way ANOVA using GraphPad Prism software (San Diego, CA, USA); and P < 0.05 was considered to indicate statistical significance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11026382	Briefly, the forward and reverse reads were merged using USEARCH.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Briefly", ",", "the", "forward", "and", "reverse", "reads", "were", "merged", "using"...
PMC11792888	Single treatments produced a significant accumulation of cells arrested at the G2/M phase for both scorpion venom (28.76 ± 3.40%) and etoposide (38.96 ± 1.95%) alone compared to the control (13.05 ± 1.94%) (p < 0.05).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11738017	TCE binding assay.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "TCE", "binding", "assay", "." ] } ]
PMC7582629	The two approaches can validate each other for a more robust analysis .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "two", "approaches", "can", "validate", "each", "other", "for", "a", ...
PMC8864075	siRNA sequences were designed and synthesized by GenePharma (Shanghai, China).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "siRNA", "sequences", "were", "designed", "and", "synthesized", "by", "GeneP...
PMC11672881	CU has been reported to disrupt glutamine metabolism, reducing tumor growth availability, and promoting apoptosis in melanoma cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CU", "has", "been", "r...
PMC11769522	Canine progenitor epidermal keratinocytes (CPEKs) were incubated with IL-4, IL-13, an IL4/IL13 mixture, IFN-γ, TNF-α, or an IFN-γ/TNF-α mixture.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9351137	We found that the midbody localizations of BAF53a, Tip60, and MKLP1 are significantly affected in HeLa cells treated for 35 min with ZM447439, compared to that in DMSO-treated controls (Fig. 7A–C and Table 4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11711871	The residual tension (RDT) corresponded to the tension (after subtraction of the corresponding RT) following contraction with Phe (10 M), measured at the time the first dose of vasodilator was added.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11756514	C-type lectins of the innate immune system. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "C-type", "lectins", "of", "the", "innate", "immune", "system", ".", "(" ] } ]
PMC11634794	The statistical analysis was performed using SPSS statistical software and Graphpad Prism8.4.3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "statistical", "analysis", "was", "performed", "using", "SPSS", "statistical", ...
PMC11525028	Treatment with both inhibitors resulted in impaired cell proliferation and metastasis of osteosarcoma in vitro and in vivo.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Treatment", "with", "both", "inhibitors", ...
PMC11694625	ESI-HRMS: m/z calculated for [C30H22N8+H]: 495.20457, found: 495.20380.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ESI-HRMS", ":", "m/z", "calculated", "for", "[", "C30H22N8+H", "...
PMC9918897	Based on our results, another important aspect could be the reduction in alcohol content.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Based", "on", "our", "results", ",", "another", "important"...
PMC11742864	Although the relationship between ROS and cell apoptosis needs to be further explored, the anti-tumor properties of ω-3 LCPUFAs that were mediated by ROS are confirmed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11680982	Fig. 2Efficacy of CDK4/6 inhibitor combined with endocrine therapy in the ZR-75-1 cell line in vitro and in vivo. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": ...
PMC11519583	Fig. 5Wnt11-Ror2 signaling suppresses cellular senescence of MPs by maintaining nuclear membrane integrity.a Representative images of MPs, taken 2 days after transfection with the indicated siRNAs, were obtained following staining with Phalloidin (green) and DAPI (magenta).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7987994	The velocity, however, is not specified.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "velocity", ",", "however", ",", "is", "not", "specified", "." ] } ]
PMC11643491	Ex vivo, A375+ cells were more invasive in the spheroid collagen invasion assay and in vivo induced 64% larger tumors when injected into mice compared to A375− cells .	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11512230	It was found that TMV SP adsorbed more effectively on the established sarcoma cell line A673 than on fibroblasts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "It", "was", "found", "th...
PMC11699178	The annotation indicated a significant overexpression of HIF-1α in ovarian cancer tissues (Fig. 2F), which was also widely expressed in the scRNA-seq data set (Fig. 2G).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10158546	By embedding ReN cells within Matrigel, they can also be differentiated as thin-3D cultures.	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "By", "embedding", "ReN", "cells", "within", "Matrigel", ...
PMC9429973	27 (34%) pts had a past history of clinically significant cardiovascular disease or high risk profile for cardiovascular disease.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "27", "(", ...
PMC11594806	Interestingly, extracellular ATP (eATP) can increase plasma membrane permeability by opening P2X7 receptor (P2X7R) pores, facilitating the entry of cytotoxic agents like doxorubicin (DOX) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10671321	Using different biochemical methods and various cell systems including iPSC from the patient, we show that the pathogenic variant in the ColQ D-CTD neither affects the association of this mutated ColQ with AChE, nor the formation of the collagen triple helix, nor the secretion of the hetero-oligomer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11670407	To ensure that the altered ubiquitination was of GPX4 itself and not its interactors, total lysates were boiled to denature the protein to break noncovalent bonds prior to antibody immunoprecipitation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11758416	The number of L cells for a 10:1 (Effector:Target) ratio would then be 5E3 L cells per well.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "numbe...
PMC9111184	2 × 10 cells/cm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "2", "", "×", "10", "cells/cm", "." ] } ]
PMC11543885	Quencher Buffer (100 mL) CRITICAL: Freshly prepared before use.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Quencher", "Buffer", "(", "100", "mL", ")", "CRITICAL", ":", "Freshly", "p...
PMC9429973	The median age of the participants was 28 years (7-52) with a sex ratio of 1.52.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "median", "age", ...
PMC10719213	DNA (5 μg) was digested with PvuII then separated on a 0.8% agarose gel followed by alkaline transfer to Hybond-XL membrane (GE Healthcare).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7823217	Hypoxia or low oxygen can lead to excessive cell proliferation within tumor tissue; highly proliferative cancer cells can generate local hypoxia within tumors under in vivo conditions increasing the percentage of non-proliferating viable hypoxic tumor and/or cancer stem cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Comparative analysis were made from the expression property of CAR protein, in vitro and in vivo anti-leukemia efficacy to screen out the best candidate CD123 CAR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	This model can be utilized as a systemic model of MCL via intravenous (iv) tail vein or subcutaneous (sc) flank engraftment and reach early removal criteria by approximately day 21 showing disease pathology consistent with MCL.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11626627	Additionally, our study has not yet incorporated validation using clinical samples, including the application of novel gene-targeted non-coding RNA drugs in clinical settings.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11705547	TAMs have also been shown to promote cisplatin resistance in tumor cells by enhance WTAP-mediated N6-methyladenosine RNA methylation through the CXCL16/CXCR6 axis .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TAMs", "have...
PMC6222726	The problem connected with its use is the scarce amount isolated from natural sources.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "problem", "connected", "with", "its", "use", "is", "the",...
PMC7812570	Despite considerable progress, it is still disappointing that allogeneic transplantation of CCR5 gene-edited HSCs has achieved only minor therapeutic efficacy in patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Despite...
PMC11534035	CAL39 cells treated with 2.5 μM of G36, however, showed significantly less gap area at the measured time intervals compared to the ethanol control cells (10h: M=0.358±0.064 vs. control=0.657±0.050; p<0.01; 20h: M=0.041±0.025 vs. control=0.202±0.053; p<0.05).	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11502443	Five microliters of acceptor beads coated with a Captsure tag immobilizing an ERK1/2, AKT, or CREB-specific antibody was added and incubated at room temperature in the dark for 1 h. Five microliters of donor beads coated with streptavidin, which captures a biotinylated antibody specific for the phosphorylated protein, ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11637276	To discern whether PPP2R1A regulated ECM internalisation through its phosphatase activity or via the regulation of actin polymerisation, we assessed collagen I uptake in the presence of okadaic acid, a PP2A inhibitor , and found that 50 nM okadaic acid significantly reduced collagen I internalisation after 6 h treatmen...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9164404	Abplatin labelled with Cy7.5 was i.v.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Abplatin", "labelled", "with", "Cy7.5", "was", "i.v", "." ] } ]
PMC11337594	Add 0.8 mL of complete culture medium to the lower chamber of the Transwell as a chemoattractant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Add", "0.8", "mL", "of", "complete", "cultu...
PMC9964635	The structures of all of the triazole-based scaffolds were confirmed by spectroscopy and physiochemical methods.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "structures", "of", "all", "of", "the", "triazole-bas...
PMC11354239	The TNFSF4 gene encodes a tumor necrosis factor superfamily member, the OX40 ligand (OX40L), which is known to increase NK cell expansion and promote NK cell function by activating the OX40 cascade .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7840816	Therefore, there is an urgent need to explore the molecular mechanisms responsible for PTC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "there", "is", "an", "urgent", "need", ...
PMC11290772	The NK cells were cultured from PBMCs of those patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "NK", "cells", "were", "cultured", "from", "PBMCs", "of", "those", "patients", "." ...
PMC10994876	Following a 15-min incubation on ice, the cellular debris was removed by centrifugation at 12,000 × g at 4 °C for 20 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10547921	It was first approved by the European Medicines Agency (EMA) in September 2017.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "was", "first", "approved", "by", "the", "European", ...
PMC11470999	UPS involves covalently attaching ubiquitin molecules to target proteins, marking them for degradation by the proteasome.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "UPS", "involves", "covalently", "attaching", "ubi...
PMC11740399	Fig. 4Compound 3K enhanced the anti-tumor activity of OXA and induced cell apoptosis by inhibiting PKM2 and FASN.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "4Compound", "3", "K", ...
PMC11790971	a–c t-SNE plots illustrating the distributions of cells from four cell lines in passage 0, passage 1, and passage 2, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11791264	Subsequently, the supernatant containing the lentivirus was harvested at 48 and 72 h post-transfection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Subsequently", ",", "the", "supernatant", "containing", "the", ...
PMC11787381	Multifactorial diseases, like AD, require pleiotropic approaches to be more clinically relevant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Multifactorial", "diseases", ",", "like", "AD", ",", "require", ...
PMC9429973	Aims: To assess outcomes in ZUMA-3 by prior number of therapy lines, prior blinatumomab, prior allogeneic stem cell transplant (alloSCT), and subsequent alloSCT.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11637276	As PAK1 can be activated by Cdc42, this raises the intriguing hypothesis that PAK1 might promote MAP3K1-dependent p38 activation, leading to ECM uptake, downstream of collagen I binding to α2β1 integrin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4270159	Semi-logarithmic graph for each condition of primary kinase inhibitor (log) vs normalized cell viability (linear) for each cell line [comparable to Figure 2B].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11761919	seral LDH. (	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "seral", "LDH", ".", "(" ] } ]
PMC9545474	Interestingly, none of the complexes showed selectivity towards non‐small‐cell lung cancerous cells (H460) versus normal cells (PNT2), while a 2–3×selectivity towards cancerous ovarian cells (A2780 and A2780cisR) versus normal cells (PNT2) was observed for complexes 6 and 8.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10719213	After TMRM staining, cells were analyzed by flow cytometry (Accuri C6, Becton Dickinson or a BD LSR II).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "TMR...
PMC11694066	Nine independent and randomly selected sites were scanned per well.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Nine", "independent", "and", "randomly", "selected", "sites", "were", "scanned", "per", "well", ...
PMC11240052	In addition, SIRT-1 mRNA and protein expression were down regulated in miR-211-5p overexpressed ovarian cancer cell lines and up regulated in ovarian cancer cell lines with low expression miR-211-5p (Figure 4d, e).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8427838	The cells were washed once with PBS and fixed with freshly prepared 4% paraformaldehyde for 15 min at room temperature.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cells", "w...
PMC11345828	NH4Cl, sat.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "NH4Cl", ",", "sat", "." ] } ]
PMC9429973	Summary/Conclusion: In this study, serum albumin and NLR emerge as reliable predictors for survival for FL patients in Latin America.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Summary/Conclusion...
PMC7351993	If this sorting experiment was manually performed by conventional Raman microscopy with pipetting, it would take more than 10 days, but we performed it within 10 min (about 400 times faster).Fig.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8303372	The obtained results showed a difference in toxicity between the two forms only at a concentration of 350 µmol/L. In this case, GA-f caused a higher toxic effect than GA-NPs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11627398	However, excess copper can cause cellular toxicity, ultimately leading to cell death .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "excess", "copper", "can", "cause", "cellular", "...
PMC5916734	Panel A – gene copy numbers for the FIX ORF region and the selection marker region (IRES).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Panel", "A", "–", "gene", "...
PMC11718109	Unlike glutamate and GABA transmitters which are primarily stored in small clear synaptic vesicles (SSVs), the vesicles storing dopamine are reportedly heterogenous in their identities.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11777207	P < 0.001, ****P < 0.0001; ns, P > 0.05.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", "<", "0.001", ",", "", "", "*",...
PMC9599726	The mean difference in green fluorescence intensity of treated cells compared to untreated cells (DMSO) for multiple independent experimental replicates are shown as scatter plots ± SD, generated using Prism 9 software (GraphPad Software, Inc., La Jolla, CA, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11078693	After the glass lid is placed on top of the over-field chamber, there will be no air gap under the lid, and no meniscus to refract trans-illumination light.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11306331	p > 0.05; : p < 0.05, : p < 0.01, **: p < 0.001.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC8750422	Following treatment, the cells were washed with PBS and lysates were prepared using a lysis buffer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Following", "treatment", ",", "the", "cells", ...
PMC11531735	All analyses were performed using R Statistical Software, p value was 0.048.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "analyses", "were", "performed", "using", "R", "Statistical", "Softwa...
PMC11361748	For topical treatment of Gö6976, 100 μm Go6976 (Cell Signaling Technology #12060S) dissolved in 10 μl acetone was applied to the dorsal side of mouse ear 30 min before the second TPA treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9622879	Other important problems of the system-centric CEMS are how to protect the private information of prosumers and a single point of failure at the central operation unit of the community.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10728200	One possibility is that RSL3, by inhibiting GPX4 activity and leading to lipid peroxidation, triggers a cellular stress response that results in alterations in gene expression, including GPX4 mRNA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11767725	However, another small study observed that only high-density lipoprotein cholesterol (HDL-C) levels were significantly lower in the patient group compared to the control group .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11532793	Results are presented for the different number of samples per group and for both Gibbs- and bootstrap-based DTE pipelines with Salmon and edgeR-v4.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results...
PMC11721064	Conversely, LN-treated groups formed regularly arranged, cobblestone-shaped structures.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Conversely", ",", "LN-treated", "groups", "formed", "regularly", "arranged", ",", "cobblestone-shaped"...
PMC11766174	Three days after infection, the cultured PBMCs were collected.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Three", "days", "after", "infection", ",", "the", "cultured", "PBMCs", "were", "collected", ...
PMC9429973	The median duration of follow-up was 38.9 months (IQR 3.5-110).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "median", "duration", "of", "follow-up", "was", "38.9", "m...

PMC9545714

Some of these supplements have demonstrated health benefits, while the effects of others are controversial.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Some", "of", "these", "supplements", "have", "demonstr...

PMC10073922

Despite the tumor specificity of various TSPs, low transcriptional efficiency usually hinders their utilization for gene therapy strategies.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Despite", "the", "tumor", "specif...

PMC11752740

The MTT assay revealed IC50 values of 2.014 mg/mL and 1.031 mg/mL in the SK-BR3 cell line, and 3.265 mg/mL and 2.994 mg/mL in the MCF10A cell line at 24- and 48-hours post-treatment with Pistachio hull extract.

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PMC11718109

Scale bars, 10 μm.

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bars", ",", "10", "μm", "." ] } ]

PMC10114490

Lentivirus was collected and concentrated using Lenti-X concentrator following manufacturer´s instructions (Takara).

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PMC11779960

Additionally, we have recently published early data from an ongoing phase I/II clinical study evaluating TRBC1 targeted autologous chimeric antigen receptor (CAR) T cells (NCT03590574) in patients with relapsed/refractory TRBC1 T cell lymphoma.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11792740

Targeting these factors offers a promising strategy to reverse exhaustion and restore T-cell functionality.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Targeting", "these", "factors", "offers", "a", "promising", "strategy"...

PMC9019892

Imatinib, nintedanib and sunitinib were dissolved in 0.5% Methylcellulose and 0.4% Tween 80 solution.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Imatinib", ",", "nintedanib", "and", "sunitinib",...

PMC11790599

The scale bar is 500 nm. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "scale", "bar", "is", "500", "nm", ".", "(" ] } ]

PMC6222635

In the HSQC spectrum, we also found the signals (93.58, 5.10) and (99.03, 4.87).

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PMC11597167

Overall, these results highlight the potential of certain phenolic compounds, particularly quercetin, EGCG, and rosmarinic acid, as promising BACE1 inhibitors.

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PMC9429973

Long-term persistence of WU-NK-101 and anti-THP-1 efficacy could be further enhanced upon repeated dosing and using fluorescently labeled WU-NK-101 cells, homing and penetration into the BM was observed.

[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "...

PMC11629461

Technologies for spatially and temporally controlled activation of NOX are, however, not readily available.

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PMC11322866

The results showed that compared with the control group, GSK126-treated cells had a higher level of p21 ( Figure 1B).

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PMC9429973

Median follow-up was 12 months (8.7-15.1).

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PMC7090062

Statistical analysis was performed by one-way ANOVA using GraphPad Prism software (San Diego, CA, USA); and P < 0.05 was considered to indicate statistical significance.

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PMC11026382

Briefly, the forward and reverse reads were merged using USEARCH.

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PMC11792888

Single treatments produced a significant accumulation of cells arrested at the G2/M phase for both scorpion venom (28.76 ± 3.40%) and etoposide (38.96 ± 1.95%) alone compared to the control (13.05 ± 1.94%) (p < 0.05).

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PMC11738017

TCE binding assay.

[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "TCE", "binding", "assay", "." ] } ]

PMC7582629

The two approaches can validate each other for a more robust analysis .

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PMC8864075

siRNA sequences were designed and synthesized by GenePharma (Shanghai, China).

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PMC11672881

CU has been reported to disrupt glutamine metabolism, reducing tumor growth availability, and promoting apoptosis in melanoma cells .

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PMC11769522

Canine progenitor epidermal keratinocytes (CPEKs) were incubated with IL-4, IL-13, an IL4/IL13 mixture, IFN-γ, TNF-α, or an IFN-γ/TNF-α mixture.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC9351137

We found that the midbody localizations of BAF53a, Tip60, and MKLP1 are significantly affected in HeLa cells treated for 35 min with ZM447439, compared to that in DMSO-treated controls (Fig. 7A–C and Table 4).

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PMC11711871

The residual tension (RDT) corresponded to the tension (after subtraction of the corresponding RT) following contraction with Phe (10 M), measured at the time the first dose of vasodilator was added.

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PMC11756514

C-type lectins of the innate immune system. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "C-type", "lectins", "of", "the", "innate", "immune", "system", ".", "(" ] } ]

PMC11634794

The statistical analysis was performed using SPSS statistical software and Graphpad Prism8.4.3.

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PMC11525028

Treatment with both inhibitors resulted in impaired cell proliferation and metastasis of osteosarcoma in vitro and in vivo.

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PMC11694625

ESI-HRMS: m/z calculated for [C30H22N8+H]: 495.20457, found: 495.20380.

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PMC9918897

Based on our results, another important aspect could be the reduction in alcohol content.

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PMC11742864

Although the relationship between ROS and cell apoptosis needs to be further explored, the anti-tumor properties of ω-3 LCPUFAs that were mediated by ROS are confirmed.

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PMC11680982

Fig. 2Efficacy of CDK4/6 inhibitor combined with endocrine therapy in the ZR-75-1 cell line in vitro and in vivo. (

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PMC11519583

Fig. 5Wnt11-Ror2 signaling suppresses cellular senescence of MPs by maintaining nuclear membrane integrity.a Representative images of MPs, taken 2 days after transfection with the indicated siRNAs, were obtained following staining with Phalloidin (green) and DAPI (magenta).

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PMC7987994

The velocity, however, is not specified.

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PMC11643491

Ex vivo, A375+ cells were more invasive in the spheroid collagen invasion assay and in vivo induced 64% larger tumors when injected into mice compared to A375− cells .

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PMC11512230

It was found that TMV SP adsorbed more effectively on the established sarcoma cell line A673 than on fibroblasts.

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PMC11699178

The annotation indicated a significant overexpression of HIF-1α in ovarian cancer tissues (Fig. 2F), which was also widely expressed in the scRNA-seq data set (Fig. 2G).

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PMC10158546

By embedding ReN cells within Matrigel, they can also be differentiated as thin-3D cultures.

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PMC9429973

27 (34%) pts had a past history of clinically significant cardiovascular disease or high risk profile for cardiovascular disease.

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PMC11594806

Interestingly, extracellular ATP (eATP) can increase plasma membrane permeability by opening P2X7 receptor (P2X7R) pores, facilitating the entry of cytotoxic agents like doxorubicin (DOX) .

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PMC10671321

Using different biochemical methods and various cell systems including iPSC from the patient, we show that the pathogenic variant in the ColQ D-CTD neither affects the association of this mutated ColQ with AChE, nor the formation of the collagen triple helix, nor the secretion of the hetero-oligomer.

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PMC11670407

To ensure that the altered ubiquitination was of GPX4 itself and not its interactors, total lysates were boiled to denature the protein to break noncovalent bonds prior to antibody immunoprecipitation.

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PMC11758416

The number of L cells for a 10:1 (Effector:Target) ratio would then be 5E3 L cells per well.

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PMC9111184

2 × 10 cells/cm.

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PMC11543885

Quencher Buffer (100 mL) CRITICAL: Freshly prepared before use.

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PMC9429973

The median age of the participants was 28 years (7-52) with a sex ratio of 1.52.

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PMC10719213

DNA (5 μg) was digested with PvuII then separated on a 0.8% agarose gel followed by alkaline transfer to Hybond-XL membrane (GE Healthcare).

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PMC7823217

Hypoxia or low oxygen can lead to excessive cell proliferation within tumor tissue; highly proliferative cancer cells can generate local hypoxia within tumors under in vivo conditions increasing the percentage of non-proliferating viable hypoxic tumor and/or cancer stem cells .

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PMC9429973

Comparative analysis were made from the expression property of CAR protein, in vitro and in vivo anti-leukemia efficacy to screen out the best candidate CD123 CAR.

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PMC9429973

This model can be utilized as a systemic model of MCL via intravenous (iv) tail vein or subcutaneous (sc) flank engraftment and reach early removal criteria by approximately day 21 showing disease pathology consistent with MCL.

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PMC11626627

Additionally, our study has not yet incorporated validation using clinical samples, including the application of novel gene-targeted non-coding RNA drugs in clinical settings.

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PMC11705547

TAMs have also been shown to promote cisplatin resistance in tumor cells by enhance WTAP-mediated N6-methyladenosine RNA methylation through the CXCL16/CXCR6 axis .

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PMC6222726

The problem connected with its use is the scarce amount isolated from natural sources.

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PMC7812570

Despite considerable progress, it is still disappointing that allogeneic transplantation of CCR5 gene-edited HSCs has achieved only minor therapeutic efficacy in patients.

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PMC11534035

CAL39 cells treated with 2.5 μM of G36, however, showed significantly less gap area at the measured time intervals compared to the ethanol control cells (10h: M=0.358±0.064 vs. control=0.657±0.050; p<0.01; 20h: M=0.041±0.025 vs. control=0.202±0.053; p<0.05).

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PMC11502443

Five microliters of acceptor beads coated with a Captsure tag immobilizing an ERK1/2, AKT, or CREB-specific antibody was added and incubated at room temperature in the dark for 1 h. Five microliters of donor beads coated with streptavidin, which captures a biotinylated antibody specific for the phosphorylated protein, ...

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PMC11637276

To discern whether PPP2R1A regulated ECM internalisation through its phosphatase activity or via the regulation of actin polymerisation, we assessed collagen I uptake in the presence of okadaic acid, a PP2A inhibitor , and found that 50 nM okadaic acid significantly reduced collagen I internalisation after 6 h treatmen...

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PMC9164404

Abplatin labelled with Cy7.5 was i.v.

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PMC11337594

Add 0.8 mL of complete culture medium to the lower chamber of the Transwell as a chemoattractant.

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PMC9964635

The structures of all of the triazole-based scaffolds were confirmed by spectroscopy and physiochemical methods.

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PMC11354239

The TNFSF4 gene encodes a tumor necrosis factor superfamily member, the OX40 ligand (OX40L), which is known to increase NK cell expansion and promote NK cell function by activating the OX40 cascade .

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PMC7840816

Therefore, there is an urgent need to explore the molecular mechanisms responsible for PTC.

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PMC11290772

The NK cells were cultured from PBMCs of those patients.

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PMC10994876

Following a 15-min incubation on ice, the cellular debris was removed by centrifugation at 12,000 × g at 4 °C for 20 min.

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PMC10547921

It was first approved by the European Medicines Agency (EMA) in September 2017.

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PMC11470999

UPS involves covalently attaching ubiquitin molecules to target proteins, marking them for degradation by the proteasome.

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PMC11740399

Fig. 4Compound 3K enhanced the anti-tumor activity of OXA and induced cell apoptosis by inhibiting PKM2 and FASN.

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PMC11790971

a–c t-SNE plots illustrating the distributions of cells from four cell lines in passage 0, passage 1, and passage 2, respectively.

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PMC11791264

Subsequently, the supernatant containing the lentivirus was harvested at 48 and 72 h post-transfection.

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PMC11787381

Multifactorial diseases, like AD, require pleiotropic approaches to be more clinically relevant.

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PMC9429973

Aims: To assess outcomes in ZUMA-3 by prior number of therapy lines, prior blinatumomab, prior allogeneic stem cell transplant (alloSCT), and subsequent alloSCT.

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PMC11637276

As PAK1 can be activated by Cdc42, this raises the intriguing hypothesis that PAK1 might promote MAP3K1-dependent p38 activation, leading to ECM uptake, downstream of collagen I binding to α2β1 integrin.

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PMC4270159

Semi-logarithmic graph for each condition of primary kinase inhibitor (log) vs normalized cell viability (linear) for each cell line [comparable to Figure 2B].

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PMC11761919

seral LDH. (

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PMC9545474

Interestingly, none of the complexes showed selectivity towards non‐small‐cell lung cancerous cells (H460) versus normal cells (PNT2), while a 2–3×selectivity towards cancerous ovarian cells (A2780 and A2780cisR) versus normal cells (PNT2) was observed for complexes 6 and 8.

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PMC10719213

After TMRM staining, cells were analyzed by flow cytometry (Accuri C6, Becton Dickinson or a BD LSR II).

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PMC11694066

Nine independent and randomly selected sites were scanned per well.

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PMC11240052

In addition, SIRT-1 mRNA and protein expression were down regulated in miR-211-5p overexpressed ovarian cancer cell lines and up regulated in ovarian cancer cell lines with low expression miR-211-5p (Figure 4d, e).

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PMC8427838

The cells were washed once with PBS and fixed with freshly prepared 4% paraformaldehyde for 15 min at room temperature.

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PMC11345828

NH4Cl, sat.

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PMC9429973

Summary/Conclusion: In this study, serum albumin and NLR emerge as reliable predictors for survival for FL patients in Latin America.

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PMC7351993

If this sorting experiment was manually performed by conventional Raman microscopy with pipetting, it would take more than 10 days, but we performed it within 10 min (about 400 times faster).Fig.

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PMC8303372

The obtained results showed a difference in toxicity between the two forms only at a concentration of 350 µmol/L. In this case, GA-f caused a higher toxic effect than GA-NPs.

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PMC11627398

However, excess copper can cause cellular toxicity, ultimately leading to cell death .

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PMC5916734

Panel A – gene copy numbers for the FIX ORF region and the selection marker region (IRES).

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PMC11718109

Unlike glutamate and GABA transmitters which are primarily stored in small clear synaptic vesicles (SSVs), the vesicles storing dopamine are reportedly heterogenous in their identities.

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PMC11777207

P < 0.001, ****P < 0.0001; ns, P > 0.05.

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PMC9599726

The mean difference in green fluorescence intensity of treated cells compared to untreated cells (DMSO) for multiple independent experimental replicates are shown as scatter plots ± SD, generated using Prism 9 software (GraphPad Software, Inc., La Jolla, CA, USA).

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PMC11078693

After the glass lid is placed on top of the over-field chamber, there will be no air gap under the lid, and no meniscus to refract trans-illumination light.

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PMC11306331

p > 0.05; *: p < 0.05, **: p < 0.01, ***: p < 0.001.

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PMC8750422

Following treatment, the cells were washed with PBS and lysates were prepared using a lysis buffer.

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PMC11531735

All analyses were performed using R Statistical Software, p value was 0.048.

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PMC11361748

For topical treatment of Gö6976, 100 μm Go6976 (Cell Signaling Technology #12060S) dissolved in 10 μl acetone was applied to the dorsal side of mouse ear 30 min before the second TPA treatment.

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PMC9622879

Other important problems of the system-centric CEMS are how to protect the private information of prosumers and a single point of failure at the central operation unit of the community.

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PMC10728200

One possibility is that RSL3, by inhibiting GPX4 activity and leading to lipid peroxidation, triggers a cellular stress response that results in alterations in gene expression, including GPX4 mRNA.

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PMC11767725

However, another small study observed that only high-density lipoprotein cholesterol (HDL-C) levels were significantly lower in the patient group compared to the control group .

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PMC11532793

Results are presented for the different number of samples per group and for both Gibbs- and bootstrap-based DTE pipelines with Salmon and edgeR-v4.

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PMC11721064

Conversely, LN-treated groups formed regularly arranged, cobblestone-shaped structures.

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PMC11766174

Three days after infection, the cultured PBMCs were collected.

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PMC9429973

The median duration of follow-up was 38.9 months (IQR 3.5-110).

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