OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC11545737	Tripeptide monomers are recognized by the Nucleotide Binding Oligomerization Domain 1 (NOD1) receptor, which induces NF-κB dependent production of TNF-α, IL-6, IL-8 and IL-1β in fallopian tube mucosa and macrophages .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The most common adverse events of grades 3-4 were infections and cytopenias.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "most", "common", "adverse", "events", "of", "grades", "3"...
PMC9325715	The pH of all prepared solutions was adjusted to 7.4 with 0.1 M sodium hydroxide or 0.1 M hydrochloric acid.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "pH", "of", "all...
PMC11770199	Mice were treated every 3 d for a total of 4 times. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mice", "were", "treated", "every", "3", "d", "for", "a", "total", ...
PMC11621493	Abundance of sn-1,2 and sn-1,3-DAG isomers, based on band intensities shown in (H). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Abundance", "of", "sn-1,2", "and", "sn-1,3-DAG", ...
PMC11774251	A-F) Representative immunofluorescence staining of K1 (A), K6 (C), and K17 (E) from the skin lesions of mice in the sham group, control group, and Tan-I treated group and quantification of K1 (B), K6 (D) and K17 (F) cells percent in epidermis cells. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11194678	LLPS of STAU1 promotes mutant HTT aggregation in the cellular HD model. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "LLPS", "of", "STAU1", "promotes", "mutant", "HTT", "aggregation", "in", ...
PMC10040136	And PI3K-AKT signaling is one of the downstream signaling pathways of KIT/PDGFRA .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "And", "PI3K-AKT", "signaling", "is", "one", "of", "the", "downstream", "signalin...
PMC11655536	However, considering the complexity of the microenvironment of MM cells in clinical settings, the therapeutic effect of HA both as a NHE1 inhibitor and a P2X7 antagonist needs to be comprehensively evaluated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11737091	The median survival time for patients with metastatic ccRCC is less than one year.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "median", "survival", "time", "for", "patients", "with", "...
PMC11673128	Interestingly, the combined effect of lorlatinib and anti-CD47 mAb was greater after long-term TKIs incubation, likely secondary to the CD47 upregulation found as a late-induced event (Figure 2C and Figure 3B, right panel).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11025866	These changes in gene expression identified by RNA-seq were validated by RT-qPCR (Fig 5).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "changes", "in", "gene", "expression", "identi...
PMC11703992	The detailed potential associations between DDIT4/ARHGAP15 and GCA are shown in Fig. S4B, C. These associations involved rs11688752 (GCA-ARHGAP15) and rs11812792 (GCA-DDIT4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11267036	After 21 days of administration, all the mice were euthanized by CO2 asphyxiation, away from other animals.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "21", "days", "of", ...
PMC11300639	l IHC staining of the tissue microarray of ccRCC (n = 38) with CDK4 or TSC1 antibodies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "l", "IHC", "staining", "of", ...
PMC11789597	p < 0.05 was considered statistically significant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "p", "<", "0.05", "was", "considered", "statistically", "significant", "." ] } ]
PMC8540692	More than 24,500 new cases of the brain & other nervous system tumors and more than 18,500 deaths are estimated to occur in 2021 in the United States .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10936243	By using a questionnaire, we were able to obtain information on the resources provided by participants to post-operative cats.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "By", "using", "a", "qu...
PMC11694625	The specific experimental process is as follows: MCF-7 cells were treated with 3b or 3c (3.5 μM and 7 μM) and incubated for 24 h at 37 °C, 5% CO2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10878518	In the malignant and intermediate group, GFP expression was significantly increased in tumors with high CAR and hTERT expressions between 24 and 48 h after OBP-401 infection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10079526	SUMO conjugation enables protein-protein interactions, regulating protein localization, degradation or enzymatic activity .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SUMO", "conjugation", "enables", "protein-protein", "interactions", ",", ...
PMC11672617	This optimal, sublethal level of mitochondria-derived ROS ions is insufficient to cause significant oxidative damage to cellular components.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "optimal", ",", "sublethal...
PMC9429973	Then we applied the brain mask and a threshold taking only the largest component.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", "we", "applied", "the", "brain", "mask", "and", "a", ...
PMC9429973	Results: As of the data cutoff on Dec 31, 2021, 60 patients in Cohort A had received ≥1 dose of elranatamab; the last patient’s first dose was ~2 months prior to the cutoff.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9841531	This finding led us to the conclusion that the observed effects are due to the selective inhibition of MCT1, which is expressed in A-549 and MCF-7 cancer cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", ...
PMC9429973	Results: Table 1 shows the characteristics of 4 CLL pts who developed biopsy-proven DLBCL.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "Table", "1", "shows", "the", "characteristi...
PMC11434983	However, since parameters such as cell p53/p21 signaling affect the radiosensitivity profile of cancer cells, the complexes will be tested in various cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11684269	GLUT enhances T cell proliferation, differentiation, and function by fueling glycolysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GLUT", "enhances", "T", "cell", "proliferation", ",", "differentiation", ",...
PMC10957991	Ca -influx, mediated by TRPV4, guides various physiological functions, including nociception through pressure-sensing and has a role in the development of functional vascular system.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11607764	We derived the human protein–protein interaction (PPI) network from the STRING database (https://string-db.org/), which covered lots of physical and functional interactions between the expressed protein.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8753818	However, recent studies have reported that caspase-3 and caspase-7 must have definite functions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "recent", "studies", "have", "reported", "that", ...
PMC9429973	Whilst there was no difference in the expression levels of TLR9 in M-CLL vs U-CLL cells, U-CLL samples expressed significantly higher basal levels of CD69 (B-cell activation marker), and their TLR9-induced migratory response negatively correlated with their basal migration.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11190538	The mixture was further subjected to freezing (−20 °C for 30–100 min) and thawing for 3–10 freeze-thaw cycles in total , stirred at 150 rpm at 4 °C for 30 min, sonicated ten times at 40 °C, 50/60 HZ, 195 W with 10-s sonication and 10-s intervals (Ultrasonics-HD, J.P. Selecta, S.A., Spain), centrifuged at 4 °C for 8 min...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11055510	Then, tumors were extracted and photographed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "tumors", "were", "extracted", "and", "photographed", "." ] } ]
PMC11772585	D The ATP production was evaluated through ATP assay kit (n = 5).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "D", "The", "ATP", "production", "was", "evaluated", "throug...
PMC6742971	It is obviously desirable that vaccines and immunotherapy preferentially activate high avidity T cells, which are more powerful than low avidity T cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10578720	We investigated the effect of HBV on the acetylation levels of human THP-1 macrophages and identified potential targets of acetylation that play a role in glucose metabolism.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10094712	It is unlikely that the recombinant protein may be involved in the regulation of the mRNA expression of the native protein.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "unlik...
PMC6160470	In order to describe the biological properties of the compounds, we used an MDR cell model.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "order", "to", "describe", "the", "bio...
PMC11724582	CAFs regulate extracellular matrix components to a large extent, and the Hippo signaling pathway is known to be related to CAFs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CAFs", "regu...
PMC11751675	Six guaianolide sesquiterpene lactone glucosides (9–14) with one germacronolide were isolated from the roots of Ixeris dentata, namely, 11β,13-dihydrozaluzanin-3-O-β-glucopyranoside (9), ixerin F (10), macrocliniside A (11), 8-epiisolipidiol-3-O-β-glucopyranoside (12), ixerisoside A (13), and ixerin M (14) were evaluat...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3888431	Similar to the individual assemblies, the non-reference (de novo) method produces a larger number of sequences than the reference-based strategy, since minor sequence differences like insertion or deletions based on sequencing errors cannot be resolved by these methods.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11781181	A gene set enrichment analysis (GSEA) revealed that mitochondrial biogenesis was disrupted in the TEN Exo group (Fig. 2E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", ...
PMC8996378	The results showed that compound 78 circumvented MDR induced by ABCB1 overexpression (Wong et al., 2005).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", "showed", "that"...
PMC11774112	A combination index (CI) value <1, =1 or >1 indicates synergism, an additive effect or antagonism, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10667689	The enzymatic activity of G6PD was elevated at 48 h after treatment with Gal-9 compared to the PMA and control group in both the THP-1 (A) and HL-60 (B) cell lines (***p < 0.001).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", ...
PMC10212663	Faget et al. and Rao et al. confirmed by public transcriptome data analysis that activation of the RANKL/RANK pathway was related with worse survival in patients with lung adenocarcinoma (LUAD).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11424574	Therefore, our findings indicate that MTA2 overexpression promotes osteosarcoma progression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "our", "findings", "indicate", "that", "MTA2", "overexpression", "promotes...
PMC11367146	When apoptosis rate increases in chondrocytes, it will lead to cartilage tear and progression of OA .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "When", "apoptosis", "rate", "increases", "in", ...
PMC9318744	In our system, the omicron variant demonstrated decreased infectivity compared with the WT virus and the delta variant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "our", "system", ",", ...
PMC11742864	ω-3 LCPUFAs were reported to lower the COX-2 expression and the synthesis of PGE2, showing the potential for anti-inflammatory or anti-proliferative activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ω-3", ...
PMC10024132	•γ9δ2 T cells can serve as effector cells for blinatumomab action.•Effector memory γ9δ2 T cells survive for at least 7 days in vivo.•Blinatumomab-secreting γ9δ2 T cells are functional in CD19+ tumor cell killing.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11670407	All patients signed a written informed consent.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "patients", "signed", "a", "written", "informed", "consent", "." ] } ]
PMC9429973	Archived tumor samples of included R/R DLBCL patients were submitted to COO subtyping with DLBCL-COO assay (Canhelp Genomics, Hangzhou, China).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC6337547	This review focuses on the chemical and pharmacological properties of polyphenols in Chinese Salvia species.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "review", "focuses", "on", "the", "chemical", "and",...
PMC11759543	Proteins were extracted after adding the doses of doxorubicin and vorinostat for another 24 h. Protein expression was analyzed by Western blot.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Proteins", "...
PMC11711063	Genomic sequences were obtained from the NCBI Nucleotide database.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Genomic", "sequences", "were", "obtained", "from", "the", "NCBI", "Nucleotide", "database", "." ] } ]
PMC11612626	Data were searched with the target PTM as a variable modification, common example PTMs, and product ion spectra.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "were", "searched", ...
PMC7887261	The ATM p.V2716A genotype was from the OncoArray study; the MLNR p.Q334V deletion genotype was from the Affymetrix study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "ATM",...
PMC11628904	N = 7–9 replicates from 3 subjects.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "N", "=", "7–9", "replicates", "from", "3", "subjects", "." ] } ]
PMC10094992	The monoclonal antibodies specific for Poly (ADP-ribose) polymerase1 (PARP-1) and α-Tubulin were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11761919	As for the neutralizing antibody induced by Fiber2 protein, a previous published article (Xie et al., 2022) reported that Fiber2 is not necessary for inducing neutralized antibodies against FAdV-4.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11206502	The median lethal dose (LD50) of HB in Sprague Dawley and Wistar rats and BALB/c mice ranges from 63 to 75 mg/kg, meaning that HB shows moderate toxicity .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11777207	We previously characterized a signaling motif within the cytoplasmic tail of PD-L1 that promoted dermal DC migration to the dLN upon polyI:C immunization and cutaneous Listeria monocytogenes infection in mice (26).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9019892	The discovery of imatinib (Glivec), a targeted tyrosine kinase inhibitor, has led to dramatic changes in the clinical management of GISTs .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC4816271	We therefore used a different binder family, which was humanized.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "therefore", "used", "a", "different", "binder", "family", ",", "which", "was", ...
PMC9065483	RNA was extracted from cell lysates at 8 and 24 hpi and probed for VSV-M and VSV-N gene expression by qPCR (n = 4, mean ± SD; ∗p < 0.05, ∗∗p < 0.01 by one-way ANOVA, n.s.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11772585	Moreover, METTL1 knockdown weakened cSCC tumorigenesis in nude mice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "METTL1", "knockdown", "weakened", "cSCC", "tumorigenesis", "in", "nude", "mice"...
PMC11469524	Thus, by integrated phosphoproteomic analysis, we have uncovered a conserved core B cell receptor-regulated signaling network.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "by", "integrated", "phosp...
PMC11464982	A growth inhibition test was performed at seven concentrations ranging from 88 to 5640 U/mL (corresponding to 158 to 10,100 μg TOS/mL) in a short‐term treatment (6 h followed by 18 h recovery period) with or without metabolic activation (S9‐mix), and in continuous treatments (24 h without recovery) in the absence of S9...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11687167	More than a decade ago, Ruan et al. identified a possible role for NF-κB in regulating RORγt gene expression in Th17 cell differentiation and function .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9780037	In conclusion, sensitive quantification of cyt c in patient serum emerges as a noninvasive prognosis biomarker to assess the effectiveness of cancer therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11472639	Cells were treated with a fixable viability stain 510 (FVS510, BV510), following manufacturer instructions (BD Biosciences, Wokingham, UK) for 15-min at room temperature, washed by centrifugation at 500×g for 5-min, 21 °C and resuspended in 100 μL of MACS buffer (PBS, 10% [v/v] HI-FCS, and 2 mM EDTA [Invitrogen™, Therm...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11711127	Equally, as mentioned, expression of Ly49 identifies CD8+ Tregs and is homologous to the inhibitory killer cell immunoglobulin-like receptors (KIRs) on human NK cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10932641	Same sex mates were housed together in individually ventilated cages with three mice per cage.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Same", "sex", "mates", "were", "housed", "together", "in", ...
PMC11521786	C57BL/6 mice were immunized with murine ErbB3-ECD (200 μg) adjuvanted in VSSP (200 μg)/Montanide (intramuscularly (im.), 50 μL).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11521786	All cells were grown at 37°C in a humidified atmosphere containing 5% CO2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "cells", "were", "grown", "at", "37", "°",...
PMC4270159	Crizotinib blocks HGF-induced pMET and pERK activation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Crizotinib", "blocks", "HGF-induced", "pMET", "and", "pERK", "activation", "." ] } ]
PMC8984067	In this research, an up-conversion nanoplatform (anti-EpCAM-UCNPs-Ce6) comodified by Ce6 and anti-EpCAM was successfully fabricated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this", "research", ",", "an", ...
PMC11240052	In the newest article, the role of this gene in ovary function and polycystic ovary syndrome (PCOS) has been shown (45).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9479186	When OXPHOS changes, it will affect the change of ROS content, which will lead to a variety of tumor biological phenotypes (23, 30, 31).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11591052	These data demonstrate the positive impact of 20E on glycolysis and one-carbon metabolism in both C2C12 and NIH3T3 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O" ], "tokens": [ "These", "data", "demo...
PMC11752740	All analyses were conducted using SPSS-18 software.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "analyses", "were", "conducted", "using", "SPSS-18", "software", "." ] } ]
PMC9454178	Collectively, these results revealed that CDK7 mediates c-KIT expression through OSR1.Fig.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Collectively", ",", "these", "results", "revealed", "that", "CDK7", "mediates", ...
PMC11566417	CM was also collected from bovine adipose tissue-derived (AD), bone marrow-derived (BM) and peripheral-blood derived (PB) mesenchymal stem/stromal cells (MSCs) and used in antimicrobial assays.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Patients with MM were included if they received a second line of treatment with KRd induction followed by a second auto-HCT between January 2016 and December 2018.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11590870	Tryptophan has been found to enter cancer cells by the endocytic pathway and binds to the major groove of nuclear DNA .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tryptophan", "has", ...
PMC9454852	We thus conducted clonogenic assays to measure the effect of BOLD-100 on cell viability for a longer term.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "thus", "conducted", "clonogenic", ...
PMC11122631	Marine prostanoids are found in different genera of soft corals, such as C. viridis, Plexaura homomalla , and Telesto riisei .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Marine", "pr...
PMC10788478	In both HCC15 and A427 cells, siRNA‐mediated LGR6 knockdown resulted in in vitro growth inhibition (Figure 1b–d), suggesting that LGR6 overexpression promotes tumor growth of CTNNB1‐mutated NSCLC cells.	[ { "tags": [ "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11144200	However, in clinical trials or animal models that are relevant to medicine, the majority of techniques have not been able to lessen the toxicity of DOX .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10024132	The level of cytotoxicity was comparable to that observed after combined treatment with γ9δ2 T cells and blinatumomab.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "level", "of", "cytotoxicity", "...
PMC11794847	After our in vitro observations, we felt that it was imperative to verify these results within a more complex, physiologically relevant system.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10874773	These suggested that the compounds oligandriortholactone (104) and neomajucin (44) showed weak inhibitory activities of β-glucuronidase release from rat PMNs induced by PAF (Tang et al., 2009).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11640247	GFP intensity in individual cells expressing Rac3-R66W in bin 1–3 at P0.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GFP", "intensity", "in", "individual", "cells", "expressing", "Rac3-R66W", "in", ...
PMC11755467	Sequences GATTGTTACT and TAACAGTC correspond to these sites, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Sequences", "GATTGTTACT", "and", "TAACAGTC", "correspond", "to", "these", "sites", ",", "respect...
PMC10932641	All nude mice were successfully inoculated, and there were no premature deaths among them.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "nude", "mice", "were", "successfully", "inoculated", ...
PMC11787355	In gliomas, PTPRZ1 takes part in cancer cell proliferation, migration, and invasiveness.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "gliomas", ",", "PTPRZ1", "takes", "part", "in", ...
PMC8873393	The model proposes that CSB recruits CSA to TSS sites, mediating the ubiquitination and degradation of the ATF3 repressor on chromatin to elicit the restart of RNA synthesis after genotoxic stress .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10545062	During the CCP, there were 20 test boluses (fluid responsive: 95.0%, fluid nonresponsive: 5.0%) in the SCC (5 mL/kg) group, and 21 test boluses (fluid responsive: 95.2%, fluid partially responsive: 4.8%, fluid nonresponsive: 0%) in the SCC+ (3 mL/kg) group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11545737

Tripeptide monomers are recognized by the Nucleotide Binding Oligomerization Domain 1 (NOD1) receptor, which induces NF-κB dependent production of TNF-α, IL-6, IL-8 and IL-1β in fallopian tube mucosa and macrophages .

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PMC9429973

The most common adverse events of grades 3-4 were infections and cytopenias.

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PMC9325715

The pH of all prepared solutions was adjusted to 7.4 with 0.1 M sodium hydroxide or 0.1 M hydrochloric acid.

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PMC11770199

Mice were treated every 3 d for a total of 4 times. (

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PMC11621493

Abundance of sn-1,2 and sn-1,3-DAG isomers, based on band intensities shown in (H). (

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PMC11774251

A-F) Representative immunofluorescence staining of K1 (A), K6 (C), and K17 (E) from the skin lesions of mice in the sham group, control group, and Tan-I treated group and quantification of K1 (B), K6 (D) and K17 (F) cells percent in epidermis cells. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11194678

LLPS of STAU1 promotes mutant HTT aggregation in the cellular HD model. (

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PMC10040136

And PI3K-AKT signaling is one of the downstream signaling pathways of KIT/PDGFRA .

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PMC11655536

However, considering the complexity of the microenvironment of MM cells in clinical settings, the therapeutic effect of HA both as a NHE1 inhibitor and a P2X7 antagonist needs to be comprehensively evaluated.

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PMC11737091

The median survival time for patients with metastatic ccRCC is less than one year.

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PMC11673128

Interestingly, the combined effect of lorlatinib and anti-CD47 mAb was greater after long-term TKIs incubation, likely secondary to the CD47 upregulation found as a late-induced event (Figure 2C and Figure 3B, right panel).

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PMC11025866

These changes in gene expression identified by RNA-seq were validated by RT-qPCR (Fig 5).

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PMC11703992

The detailed potential associations between DDIT4/ARHGAP15 and GCA are shown in Fig. S4B, C. These associations involved rs11688752 (GCA-ARHGAP15) and rs11812792 (GCA-DDIT4).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11267036

After 21 days of administration, all the mice were euthanized by CO2 asphyxiation, away from other animals.

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PMC11300639

l IHC staining of the tissue microarray of ccRCC (n = 38) with CDK4 or TSC1 antibodies.

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PMC11789597

p < 0.05 was considered statistically significant.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "p", "<", "0.05", "was", "considered", "statistically", "significant", "." ] } ]

PMC8540692

More than 24,500 new cases of the brain & other nervous system tumors and more than 18,500 deaths are estimated to occur in 2021 in the United States .

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PMC10936243

By using a questionnaire, we were able to obtain information on the resources provided by participants to post-operative cats.

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PMC11694625

The specific experimental process is as follows: MCF-7 cells were treated with 3b or 3c (3.5 μM and 7 μM) and incubated for 24 h at 37 °C, 5% CO2.

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PMC10878518

In the malignant and intermediate group, GFP expression was significantly increased in tumors with high CAR and hTERT expressions between 24 and 48 h after OBP-401 infection.

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PMC10079526

SUMO conjugation enables protein-protein interactions, regulating protein localization, degradation or enzymatic activity .

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PMC11672617

This optimal, sublethal level of mitochondria-derived ROS ions is insufficient to cause significant oxidative damage to cellular components.

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PMC9429973

Then we applied the brain mask and a threshold taking only the largest component.

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PMC9429973

Results: As of the data cutoff on Dec 31, 2021, 60 patients in Cohort A had received ≥1 dose of elranatamab; the last patient’s first dose was ~2 months prior to the cutoff.

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PMC9841531

This finding led us to the conclusion that the observed effects are due to the selective inhibition of MCT1, which is expressed in A-549 and MCF-7 cancer cell lines.

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PMC9429973

Results: Table 1 shows the characteristics of 4 CLL pts who developed biopsy-proven DLBCL.

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PMC11434983

However, since parameters such as cell p53/p21 signaling affect the radiosensitivity profile of cancer cells, the complexes will be tested in various cell lines.

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PMC11684269

GLUT enhances T cell proliferation, differentiation, and function by fueling glycolysis.

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PMC10957991

Ca -influx, mediated by TRPV4, guides various physiological functions, including nociception through pressure-sensing and has a role in the development of functional vascular system.

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PMC11607764

We derived the human protein–protein interaction (PPI) network from the STRING database (https://string-db.org/), which covered lots of physical and functional interactions between the expressed protein.

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PMC8753818

However, recent studies have reported that caspase-3 and caspase-7 must have definite functions.

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PMC9429973

Whilst there was no difference in the expression levels of TLR9 in M-CLL vs U-CLL cells, U-CLL samples expressed significantly higher basal levels of CD69 (B-cell activation marker), and their TLR9-induced migratory response negatively correlated with their basal migration.

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PMC11190538

The mixture was further subjected to freezing (−20 °C for 30–100 min) and thawing for 3–10 freeze-thaw cycles in total , stirred at 150 rpm at 4 °C for 30 min, sonicated ten times at 40 °C, 50/60 HZ, 195 W with 10-s sonication and 10-s intervals (Ultrasonics-HD, J.P. Selecta, S.A., Spain), centrifuged at 4 °C for 8 min...

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PMC11055510

Then, tumors were extracted and photographed.

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PMC11772585

D The ATP production was evaluated through ATP assay kit (n = 5).

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PMC6742971

It is obviously desirable that vaccines and immunotherapy preferentially activate high avidity T cells, which are more powerful than low avidity T cells.

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PMC10578720

We investigated the effect of HBV on the acetylation levels of human THP-1 macrophages and identified potential targets of acetylation that play a role in glucose metabolism.

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PMC10094712

It is unlikely that the recombinant protein may be involved in the regulation of the mRNA expression of the native protein.

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PMC6160470

In order to describe the biological properties of the compounds, we used an MDR cell model.

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PMC11724582

CAFs regulate extracellular matrix components to a large extent, and the Hippo signaling pathway is known to be related to CAFs.

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PMC11751675

Six guaianolide sesquiterpene lactone glucosides (9–14) with one germacronolide were isolated from the roots of Ixeris dentata, namely, 11β,13-dihydrozaluzanin-3-O-β-glucopyranoside (9), ixerin F (10), macrocliniside A (11), 8-epiisolipidiol-3-O-β-glucopyranoside (12), ixerisoside A (13), and ixerin M (14) were evaluat...

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PMC3888431

Similar to the individual assemblies, the non-reference (de novo) method produces a larger number of sequences than the reference-based strategy, since minor sequence differences like insertion or deletions based on sequencing errors cannot be resolved by these methods.

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PMC11781181

A gene set enrichment analysis (GSEA) revealed that mitochondrial biogenesis was disrupted in the TEN Exo group (Fig. 2E).

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PMC8996378

The results showed that compound 78 circumvented MDR induced by ABCB1 overexpression (Wong et al., 2005).

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PMC11774112

A combination index (CI) value <1, =1 or >1 indicates synergism, an additive effect or antagonism, respectively.

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PMC10667689

The enzymatic activity of G6PD was elevated at 48 h after treatment with Gal-9 compared to the PMA and control group in both the THP-1 (A) and HL-60 (B) cell lines (***p < 0.001).

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PMC10212663

Faget et al. and Rao et al. confirmed by public transcriptome data analysis that activation of the RANKL/RANK pathway was related with worse survival in patients with lung adenocarcinoma (LUAD).

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PMC11424574

Therefore, our findings indicate that MTA2 overexpression promotes osteosarcoma progression.

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PMC11367146

When apoptosis rate increases in chondrocytes, it will lead to cartilage tear and progression of OA .

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PMC9318744

In our system, the omicron variant demonstrated decreased infectivity compared with the WT virus and the delta variant.

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PMC11742864

ω-3 LCPUFAs were reported to lower the COX-2 expression and the synthesis of PGE2, showing the potential for anti-inflammatory or anti-proliferative activity.

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PMC10024132

•γ9δ2 T cells can serve as effector cells for blinatumomab action.•Effector memory γ9δ2 T cells survive for at least 7 days in vivo.•Blinatumomab-secreting γ9δ2 T cells are functional in CD19+ tumor cell killing.

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PMC11670407

All patients signed a written informed consent.

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PMC9429973

Archived tumor samples of included R/R DLBCL patients were submitted to COO subtyping with DLBCL-COO assay (Canhelp Genomics, Hangzhou, China).

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PMC6337547

This review focuses on the chemical and pharmacological properties of polyphenols in Chinese Salvia species.

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PMC11759543

Proteins were extracted after adding the doses of doxorubicin and vorinostat for another 24 h. Protein expression was analyzed by Western blot.

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PMC11711063

Genomic sequences were obtained from the NCBI Nucleotide database.

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PMC11612626

Data were searched with the target PTM as a variable modification, common example PTMs, and product ion spectra.

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PMC7887261

The ATM p.V2716A genotype was from the OncoArray study; the MLNR p.Q334V deletion genotype was from the Affymetrix study.

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PMC11628904

N = 7–9 replicates from 3 subjects.

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PMC10094992

The monoclonal antibodies specific for Poly (ADP-ribose) polymerase1 (PARP-1) and α-Tubulin were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA).

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PMC11761919

As for the neutralizing antibody induced by Fiber2 protein, a previous published article (Xie et al., 2022) reported that Fiber2 is not necessary for inducing neutralized antibodies against FAdV-4.

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PMC11206502

The median lethal dose (LD50) of HB in Sprague Dawley and Wistar rats and BALB/c mice ranges from 63 to 75 mg/kg, meaning that HB shows moderate toxicity .

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PMC11777207

We previously characterized a signaling motif within the cytoplasmic tail of PD-L1 that promoted dermal DC migration to the dLN upon polyI:C immunization and cutaneous Listeria monocytogenes infection in mice (26).

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PMC9019892

The discovery of imatinib (Glivec), a targeted tyrosine kinase inhibitor, has led to dramatic changes in the clinical management of GISTs .

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PMC4816271

We therefore used a different binder family, which was humanized.

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PMC9065483

RNA was extracted from cell lysates at 8 and 24 hpi and probed for VSV-M and VSV-N gene expression by qPCR (n = 4, mean ± SD; ∗p < 0.05, ∗∗p < 0.01 by one-way ANOVA, n.s.

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PMC11772585

Moreover, METTL1 knockdown weakened cSCC tumorigenesis in nude mice.

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PMC11469524

Thus, by integrated phosphoproteomic analysis, we have uncovered a conserved core B cell receptor-regulated signaling network.

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PMC11464982

A growth inhibition test was performed at seven concentrations ranging from 88 to 5640 U/mL (corresponding to 158 to 10,100 μg TOS/mL) in a short‐term treatment (6 h followed by 18 h recovery period) with or without metabolic activation (S9‐mix), and in continuous treatments (24 h without recovery) in the absence of S9...

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PMC11687167

More than a decade ago, Ruan et al. identified a possible role for NF-κB in regulating RORγt gene expression in Th17 cell differentiation and function .

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PMC9780037

In conclusion, sensitive quantification of cyt c in patient serum emerges as a noninvasive prognosis biomarker to assess the effectiveness of cancer therapy.

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PMC11472639

Cells were treated with a fixable viability stain 510 (FVS510, BV510), following manufacturer instructions (BD Biosciences, Wokingham, UK) for 15-min at room temperature, washed by centrifugation at 500×g for 5-min, 21 °C and resuspended in 100 μL of MACS buffer (PBS, 10% [v/v] HI-FCS, and 2 mM EDTA [Invitrogen™, Therm...

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PMC11711127

Equally, as mentioned, expression of Ly49 identifies CD8+ Tregs and is homologous to the inhibitory killer cell immunoglobulin-like receptors (KIRs) on human NK cells.

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PMC10932641

Same sex mates were housed together in individually ventilated cages with three mice per cage.

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PMC11521786

C57BL/6 mice were immunized with murine ErbB3-ECD (200 μg) adjuvanted in VSSP (200 μg)/Montanide (intramuscularly (im.), 50 μL).

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PMC11521786

All cells were grown at 37°C in a humidified atmosphere containing 5% CO2.

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PMC4270159

Crizotinib blocks HGF-induced pMET and pERK activation.

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PMC8984067

In this research, an up-conversion nanoplatform (anti-EpCAM-UCNPs-Ce6) comodified by Ce6 and anti-EpCAM was successfully fabricated.

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PMC11240052

In the newest article, the role of this gene in ovary function and polycystic ovary syndrome (PCOS) has been shown (45).

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PMC9479186

When OXPHOS changes, it will affect the change of ROS content, which will lead to a variety of tumor biological phenotypes (23, 30, 31).

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PMC11591052

These data demonstrate the positive impact of 20E on glycolysis and one-carbon metabolism in both C2C12 and NIH3T3 cells.

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PMC11752740

All analyses were conducted using SPSS-18 software.

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PMC9454178

Collectively, these results revealed that CDK7 mediates c-KIT expression through OSR1.Fig.

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PMC11566417

CM was also collected from bovine adipose tissue-derived (AD), bone marrow-derived (BM) and peripheral-blood derived (PB) mesenchymal stem/stromal cells (MSCs) and used in antimicrobial assays.

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PMC9429973

Patients with MM were included if they received a second line of treatment with KRd induction followed by a second auto-HCT between January 2016 and December 2018.

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PMC11590870

Tryptophan has been found to enter cancer cells by the endocytic pathway and binds to the major groove of nuclear DNA .

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PMC9454852

We thus conducted clonogenic assays to measure the effect of BOLD-100 on cell viability for a longer term.

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PMC11122631

Marine prostanoids are found in different genera of soft corals, such as C. viridis, Plexaura homomalla , and Telesto riisei .

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PMC10788478

In both HCC15 and A427 cells, siRNA‐mediated LGR6 knockdown resulted in in vitro growth inhibition (Figure 1b–d), suggesting that LGR6 overexpression promotes tumor growth of CTNNB1‐mutated NSCLC cells.

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PMC11144200

However, in clinical trials or animal models that are relevant to medicine, the majority of techniques have not been able to lessen the toxicity of DOX .

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PMC10024132

The level of cytotoxicity was comparable to that observed after combined treatment with γ9δ2 T cells and blinatumomab.

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PMC11794847

After our in vitro observations, we felt that it was imperative to verify these results within a more complex, physiologically relevant system.

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PMC10874773

These suggested that the compounds oligandriortholactone (104) and neomajucin (44) showed weak inhibitory activities of β-glucuronidase release from rat PMNs induced by PAF (Tang et al., 2009).

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PMC11640247

GFP intensity in individual cells expressing Rac3-R66W in bin 1–3 at P0.

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PMC11755467

Sequences GATTGTTACT and TAACAGTC correspond to these sites, respectively.

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PMC10932641

All nude mice were successfully inoculated, and there were no premature deaths among them.

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PMC11787355

In gliomas, PTPRZ1 takes part in cancer cell proliferation, migration, and invasiveness.

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PMC8873393

The model proposes that CSB recruits CSA to TSS sites, mediating the ubiquitination and degradation of the ATF3 repressor on chromatin to elicit the restart of RNA synthesis after genotoxic stress .

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PMC10545062

During the CCP, there were 20 test boluses (fluid responsive: 95.0%, fluid nonresponsive: 5.0%) in the SCC (5 mL/kg) group, and 21 test boluses (fluid responsive: 95.2%, fluid partially responsive: 4.8%, fluid nonresponsive: 0%) in the SCC+ (3 mL/kg) group.

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