OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC10831439	Annexin V/VD gates were set on singlets and CTV+ cells. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Annexin", "V/VD", "gates", "were", "set", "on", "singlets", "and", "CTV+", "cells", ...
PMC3915447	RPMI-1640 medium and all the additives were purchased from GIBCO Co. (Grand Island, NY, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RPMI-1640", "medium", "and", "all...
PMC11767725	Probiotics and postbiotics, aimed at enhancing microbial diversity, can suppress inflammation and dysbiosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Probiotics", "and", "postbiotics", ",", "aimed", "at", "enh...
PMC11285179	Because the action of CCL28 leads to vascular normalization, making the vascular network healthier and more regular, it may also increase the density and functionality of tumor blood vessels, providing more nutrients and oxygen to promote tumor growth.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11352311	The structures of esculin and proteins were processed by deleting water molecules and adding hydrogens using the AutoDockTools 1.5.7 software.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "structures", "of", ...
PMC7812570	In the past decade, we have focused on developing peptide-based HIV-1 fusion inhibitors, reporting a group of peptides and lipopeptides with extremely potent antiviral activity; we have also focused on identifying and characterizing human neutralizing antibodies from HIV-1-infected individuals, such as A16, Y498, and m...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11745823	RIT1 is highly expressed in glioma and is inversely correlated with prognosis. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RIT1", "is", "highly", "expressed", "in", "glioma", "and", "is", "inv...
PMC11489351	We expect that our work will open new lines of research studying pHi regulation of Notch1 as a target to prevent or treat Notch1-related diseases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11045125	Raw RNA-seq reads were aligned to a combined human genome (human release 32, GRCh38.p13, obtained from Gencode) and the AG876 Type 2 genome (GenBank accession number NC_009334) using STAR 2.7.6a .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11594641	Our findings indicate that Rab27 possesses a more significant impact on the functioning of less-invasive melanoma cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Our", "findings", "indicate", "that", "Rab27", ...
PMC10667689	Ethical approval was not required for the studies on animals in accordance with the local legislation and institutional requirements because only commercially available established cell lines were used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9895440	Informed consent was obtained from all individual participants included in the study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Informed", "consent", "was", "obtained", "from", "all", "individual", "participants", ...
PMC11036064	.	[ { "tags": [ "O" ], "tokens": [ "." ] } ]
PMC8494202	CMap analysis predicted four drugs that could negatively regulate CKAP2L.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CMap", "analysis", "predicted", "four", "drugs", "that", "could", "negatively", "regulate", "CKA...
PMC11543935	The H&E stainings in Fig. 5B-C display at the insertion point of the electrode plate anomalies that have similarities to a burn wound, while the alcian blue staining eliminates the possibility of a dye error.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6684588	Data are means ± SD of three separate experiments each performed in triplicate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "means", "±", "SD", "of", "three", "separate", "experim...
PMC8973725	Five random fields were selected on each slide for scoring, and the mean score of each slide was used in the final analyses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11467964	The primer sequences used are presented in Supporting Information S2: Table S3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "primer", "sequences", "used", "are", "presented", "in", "Supporting"...
PMC9429973	CD7-CART may result in better disease control which will translate into less disease recurrence after transplant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CD7-CART", "may", "result", "in", "better", "disease",...
PMC9429973	The high ULBP-2/5/6 group showed a superior overall survival rate compared to the low ULBP-2/5/6 group (P < 0.01), but there was no significant difference between high and low MIC-A/B groups (P = 0.31) or between the high and low ULBP-1 groups (P = 0.52).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5916734	Unlike its orthologs in other mammals, VKORC1 from Chinese hamster carries a RRR motif flanking the first transmembrane domain and shows much lower homology with the human vkorc1 gene (Fig. 2D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9352806	In each cycle, the most intensive 12 precursor ions with intensity above 100 were chosen for MS/MS at collision energy (CE) of 45 eV (12 MS/MS events with accumulation time of 50 msec each).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	A. Dorofeeva, I. Shipounova, A. Luchkin, Z. Fidarova, E. Mikhailova National Research Center for Hematology, Moscow, Russia Background: Aplastic anemia (AA) is a heterogeneous blood system disease characterized by the bone marrow (BM) aplasia in and pancytopenia.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10335954	C Result from TRIP13 inhibition on cell clone formation ability of AGS and MGC-803 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O" ], "tokens": [ "C", "Result", "from", "TRIP13", "inhibition", "...
PMC10055960	This may be due to a mechanism of action where an additive effect of the suitable physico-chemical properties of the acetate-bearing compound 8 results in enhanced activity when compared to complex 3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5854676	The mathematical model for fluorescence (a.u) is shown in Fig. 13.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mathematical", "model", "for", "fluorescence", "(", "a.u", ")", ...
PMC9895440	Images from immunofluorescence images were recorded on a Nikon Ti with a Yokogawa CSU-W1 spinning disk module on a Photometrics 95B (22 mm back-illuminated sCMOS) camera.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Score change from baseline across visits for all subscales of EORTC QLQ-C30 was analyzed with mixed models.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Score", "change", "from", "baseline", "across", ...
PMC7053076	Data are expressed as mean ± SEM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "expressed", "as", "mean", "±", "SEM", "." ] } ]
PMC9429973	Patients had received a PI, IMiD, and anti-CD38 antibody.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "had", "received", "a", "PI", ",", "IMiD", ",", "and", "anti-CD38", ...
PMC9545714	The human skin is exposed to various sources of oxidative stress including ultraviolet light, ozone, and other air pollutants and metabolism of resident microorganisms. , ,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8540692	Only one freeze-thaw cycle was used regarding Aza to ensure maximal stability.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Only", "one", "freeze-thaw", "cycle", "was", "used", "regarding", "Aza", "to", ...
PMC11085211	Each H NMR spectrum consisted of 256 scans (corresponding to 16 min) with a relaxation delay (RD) of 2 s, acquisition time of 0.707 s, and spectral width of 9595.8 Hz (corresponding to δ 16.0).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11754094	These results suggest that the sequence close to the prime editing site might contribute to the potential for large-deletion events.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "results", "suggest"...
PMC9429973	I. Schwaner, H. Hebart, C. Losem, T. Wolff, K. Famulla, J. Huelsenbeck, B. Schmidt, T. Nösslinger, D. Rossi Onkologie Kurfürstendamm, Berlin; Kliniken Ostalb, Mutlangen; MVZ Onkologie und Hämatologie, Neuss; Onkologie Lerchenfeld, Hamburg; AbbVie Deutschland GmbH & Co KG, Wiesbaden; Hämatologisch-Onkologische Gemeinsch...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7192625	The network representation is particularly useful when using PCHi-C networks, where we can subdivide the whole network into interactions involving only promoters (PP subnetwork) or those involving a promoter and an Other-end (PO subnetwork).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	A heavy comorbidity burden, namely 3 or more comorbidities (HR 2.956; 95% CI 1.403-6.227), advanced age, namely ≥70 years (HR .809; 95% CI 1.651-4.779), myelofibrosis (HR 2.501; 95% CI 1.384-4.519), and ICU admission (HR 2.669; 95% CI 1.641-4.342) independently predicted FR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11490153	All qPCR amplifications were performed in triplicate, and primers are listed in Table 1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "qPCR", "amplifications", "were", "performed", "in", ...
PMC11621565	At 10 µg/ml, no change appeared, while at 40 µg/ml there was a 1.77-fold increase (p = 0.007).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "10", ...
PMC11496491	The results of GO enrichment analysis of DEGs were presented in terms of cell component CC, biological process BP and molecular function MF.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC7723249	IFN-γ was not detected.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "IFN-γ", "was", "not", "detected", "." ] } ]
PMC9318744	In conclusion, we developed a suitable human cell model for SARS-CoV-2 susceptibility.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "conclusion", ",", "we", "developed", "a", "suitable", "human", ...
PMC10297204	However, the anti-tumor effects of ethanol adjuvant therapy on the STS field has not been established.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "anti-tumor", "effects", ...
PMC10243817	Recently, epithelial cells have been indicated as an origin of collagens in idiopathic pulmonary fibrosis (44).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Recently", ",", "epithelial", "ce...
PMC9429973	Image: Summary/Conclusion: In summary, our data show that the LSCs react differently than normal HSCs to changes in AHR signalling.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Image",...
PMC9583612	Because measurements by both SeekOps and Bridger were contemporaneous, potential diurnal variations in emissions are not expected to bias this approach.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Because", "m...
PMC11701801	I, Representative immunohistochemical staining of cleaved PARP and cleaved caspase-3 in xenografts derived from SMARCA4/SMARCA2-deficient DMS114 cell lines and isolated from mice treated once daily for 20 days with 30 mg/kg CP-C27: Scale bar, 100 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11678368	The M–Cl bonds are positioned above and below the molecular plane in trans configuration.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "M", "–", "Cl", "bonds", "are", "positione...
PMC11638255	c Volcano plot of genes upregulated and downregulated in TEPA-treated high versus low regions of interest.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "c", "Volcano", "plot", "of", "genes", "upregulated", ...
PMC11155445	Novel acyl thiourea (149) was synthesized and subjected toward drug-likeness property and binding affinity with σ1R crystal structure 5HK1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Novel", "acyl", "...
PMC11585254	The next day, cells were seeded at a density of 20,000 cells per well of a white-walled clear-bottom 96-well plate and grown overnight at 37°C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7987994	Although the choice dramatically influences the results of cytotoxicity, we have not found any papers comparing those two modes of exposition.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Although", "...
PMC11695546	Many studies illustrated the possibility of using crude coconut oil as adjuvant therapy in animals infected with H. pylori and developed gastric ulcer [Selvarajah et al. 2015; Meng et al. 2019).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6267596	Quality clustering analysis performed after calculating the Z-score (Figure 3b) which found 1,234 genes were up-regulated, and 3,186 genes were down-regulated in treatments vs. controls.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11758416	Adjust the flask size based on the cell number required.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Adjust", "the", "flask", "size", "based", "on", "the", "cell", "number", "required", "." ...
PMC11754094	Compared with targets with a TC motif, those without a TC motif had a lower frequency of either large-deletion events or small indels due to AYBE (Fig. 4b,d).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11026382	Again dotted lines indicate multiple intermediate reactions summarized with a single line.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Again", "dotted", "lines", "indicate", "multiple", "intermediate", "reactions", "summa...
PMC11612626	High-throughput screening was performed to identify compound A, a novel molecule that selectively increased immunoproteasome activity and expanded the number and diversity of MHC-I–bound peptides presented on multiple myeloma cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10588957	We examined whether DATS had an inhibitory effect on the growth of HepG2 cells, as well as the mechanism of DATS-induced pro-apoptotic autophagy, and clarified the potential role of the AMPK/SIRT1 signalling pathway.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	AITL is an aggressive malignancy with a poor prognosis, and its clinical manifestations vary greatly among individuals.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "AITL", "is", "an", "aggressive", "mali...
PMC11243198	Notably, BAS 07019774 showed significant effects on both U87MG and T98G cell viability (with IC50 values of 9.5 and 29.5 μM, respectively) (Figure 5B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC11627398	SLC31A1, also known as copper transporter 1 (CTR1), is a key copper transporter .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SLC31A1", ",", "also", "known", "as", "copp...
PMC11310713	Scale bars, 100 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bars", ",", "100", "μm", "." ] } ]
PMC11594641	Silver staining of the SDS-polyacrylamide gels was performed to visualize the protein content of the sEVs and cell lysates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Silver", "staining", "of", "the",...
PMC11534035	On average, the tumor sphere formation at 15 days after transfection (Figure 6A) showed an average reduction in knockdown compared to control cells; however, the difference was not statistically significant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11539788	Next, the beads were washed with IP lysis buffer, followed by boiling in 50 µl of SDS loading buffer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Next", ",", "the"...
PMC4355729	Linear correlation analysis was used to determine relationship between PIK3R1 and NCAD mRNA expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Linear", "correlation", "analysis", "was", "used", "to", "determine", ...
PMC3995603	The HPLC chromatograms of the standard solution and water extract of A. capillaries are shown in Figure 1B and C. The contents of the six constituents ranged from 0.44–43.14 mg/g.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11574271	Images of tumors from individual mice were captured on day 32 following the injection of J82 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Images", "of", "tumors", "from", "indivi...
PMC9429973	In some patients, imaging was the only technique applied to detect residual disease.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "some", "patients", ",", "imaging", "was", "the", "only", ...
PMC11705630	Moreover, we found increased mRNA expressions of ISGF3 target genes in GLDC knock-downed ACHN and Caki-2 cells (Fig. 3B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "...
PMC11694625	The results of docking suggested that CDK2 may be one of the targets for 3b and 3c.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", "of", "docking", "suggested", ...
PMC9780037	Using this modification procedure, each cyt c molecule was bound to either four or eight PEG molecules.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Using", "this", "modification", "procedure",...
PMC9895440	Despite its upregulation in exhausted TILs, SNX9 is rather ubiquitously expressed in humans.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Despite", "its", "upregulation", "in", "exhausted", "TILs", ",", ...
PMC8010066	All tests were done in triplicate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "tests", "were", "done", "in", "triplicate", "." ] } ]
PMC8303372	The level of significance was set at 0.05.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "level", "of", "significance", "was", "set", "at", "0.05", "." ] } ]
PMC9587866	1,7-dihydroxy-3-methylanthracene-9.10-dione also exhibited a downregulatory effect on CTSD gene, helping EWS cells to metastasize.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "1,7-dihydroxy-3-methylanthracene-9.10-dione", "also", "exhibited", "...
PMC5963610	Activation of EGFR results in the phosphorylation of several downstream proteins, which promote cell proliferation, invasion and metastasis .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Activation", "of", "EGFR", ...
PMC9509578	Their findings indicated that smaller AuNPs have more efficient binding with P-gp, whereas larger-size nanoparticles avoid effective recognition by P-gp .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Their", "findings", ...
PMC11095939	However, they did not observe the decreased mRNA levels of both LXR isoforms (Nr1h3 and Nr1h2) mainly because they monitored the transcriptional levels at 1 d post-PHx, which was not early enough to capture the upstream changes in transcriptional regulation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5963610	It is important, however, to take into account the potential difference between NGcGM3 and NAcGM3 gangliosides in terms of their interaction with the EGFR and the uPAR/integrin pathways.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11583010	E, tumor volume measured using a caliper [V = (L × W × H) × π/6)].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "E", ",", ...
PMC11721587	WB analysis of Fu and Ci phosphorylation (top) and qRT-PCR of ptc mRNA (bottom) in Cl8 cells treated with increasing dose of Hh for 6 hours. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", ...
PMC10728200	C Western blotting was performed to assess the level of GPX4 in GIST-T1 cells transfected with GPX4 overexpression plasmids or control plasmid, and treated with IM (50 nM for T1 and 200 nM for 882) in the absence or presence of MG132 (5 μM) for 24 h. D STUB1 overexpression inhibited the stability of the GPX4 protein in...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11406030	No signs of toxicity were detected, even at a very high dose of 40 mg/kg, which will allow optimization of the dose and administration frequency depending on the stability of the peptides in the serum, which we propose to determine.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11745823	The WB was utilised to evaluate MCM7, PCNA, PI3K, phosphorylated PI3K (p‐PI3K), AKT, phosphorylated AKT (p‐AKT) and c‐Myc expression levels.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Indications for neuroimaging [(magnetic resonance imaging (MRI) or magnetic resonance angiography (MRA)] in our center include recurrent episodes of syncope, epileptic seizures, neurocognitive changes, time-averaged maximum mean velocity (TAMMV) of the middle cerebral or intracranial internal carotid arteries (ICA) mea...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9219615	was thus retested for its ability to induce cell death in other cell types.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "was", "thus", "retested", "for", "its", "ability", "to", "induce...
PMC9429973	None transformed into blastic-phase disease.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "None", "transformed", "into", "blastic-phase", "disease", "." ] } ]
PMC11387401	Other proteins displaying strong, abundant RNA interactions are Nucleocapsid, Tat, Integrase, Gag, and Rev. The few interactions found for GP41, Vpr, and Vif are rather weak and sparse (Fig. 2C).Figure 2Overlap and correlation between HIV-1 protein–RNA interactors identified by four nRIPseq workflows.(A) Venn diagrams ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8735881	For example, it was found that 10E8 exhibited increased activity in neutralizing HIV-1 mutants resistant to a fusion inhibitor peptide (C34) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11459296	Analysis of IFNγ secretion revealed significantly higher levels in all three cell types following stimulation (Figure 2E–G).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Analysis", "of", ...
PMC10291556	Lactate production.	[ { "tags": [ "O", "O", "O" ], "tokens": [ "Lactate", "production", "." ] } ]
PMC11129910	Mammalian expression vectors with different oncogene inserts and control vectors were transfected into Phoenix cells cultured in DMEM media, and Lipofectamine was used as the transfection agent (Invitrogen, NY, USA) along with viral packaging vectors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9813422	Viral gene expression is regulated by epigenetic changes in viral episomes through EMPs and associated proteins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Viral", "gene", "expression", "is", "regulated", "by",...
PMC11502327	The mechanism is related to reducing the production of integrin α5β1 heterodimer, stimulating the proliferation of immune cells, and enhancing the activity of macrophages and T cells (62).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11476666	In the postformation culture, RSV seemed to be the more effective molecule, decreasing the CD44 expression levels in a significant manner (p < 0.05) in comparison to untreated and DMSO-treated cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9895440	Fig. 5Deletion of SNX9 improves CAR T cell anti-tumor efficacy.a Schematic representation of the CAR T cell transfer experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "5Deletion", "of", "SNX9",...
PMC9429973	Cytoreduction at registration comprised 44% of patients on hydroxycarbamide, 18% on Pegylated interferon, 16% on ruxolitinib and 8% on no therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11471157	Fig. 2Morphology of various cell spheroids with or without DFP Phase contrast microscopy revealed that HaCaT cells, NIH/3T3 cells and CAF cells initiate cell spheroid formation from Day 1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "...

PMC10831439

Annexin V/VD gates were set on singlets and CTV+ cells. (

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PMC3915447

RPMI-1640 medium and all the additives were purchased from GIBCO Co. (Grand Island, NY, USA).

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PMC11767725

Probiotics and postbiotics, aimed at enhancing microbial diversity, can suppress inflammation and dysbiosis.

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PMC11285179

Because the action of CCL28 leads to vascular normalization, making the vascular network healthier and more regular, it may also increase the density and functionality of tumor blood vessels, providing more nutrients and oxygen to promote tumor growth.

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PMC11352311

The structures of esculin and proteins were processed by deleting water molecules and adding hydrogens using the AutoDockTools 1.5.7 software.

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PMC7812570

In the past decade, we have focused on developing peptide-based HIV-1 fusion inhibitors, reporting a group of peptides and lipopeptides with extremely potent antiviral activity; we have also focused on identifying and characterizing human neutralizing antibodies from HIV-1-infected individuals, such as A16, Y498, and m...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11745823

RIT1 is highly expressed in glioma and is inversely correlated with prognosis. (

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PMC11489351

We expect that our work will open new lines of research studying pHi regulation of Notch1 as a target to prevent or treat Notch1-related diseases.

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PMC11045125

Raw RNA-seq reads were aligned to a combined human genome (human release 32, GRCh38.p13, obtained from Gencode) and the AG876 Type 2 genome (GenBank accession number NC_009334) using STAR 2.7.6a .

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PMC11594641

Our findings indicate that Rab27 possesses a more significant impact on the functioning of less-invasive melanoma cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Our", "findings", "indicate", "that", "Rab27", ...

PMC10667689

Ethical approval was not required for the studies on animals in accordance with the local legislation and institutional requirements because only commercially available established cell lines were used.

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PMC9895440

Informed consent was obtained from all individual participants included in the study.

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PMC11036064

.

[ { "tags": [ "O" ], "tokens": [ "." ] } ]

PMC8494202

CMap analysis predicted four drugs that could negatively regulate CKAP2L.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CMap", "analysis", "predicted", "four", "drugs", "that", "could", "negatively", "regulate", "CKA...

PMC11543935

The H&E stainings in Fig. 5B-C display at the insertion point of the electrode plate anomalies that have similarities to a burn wound, while the alcian blue staining eliminates the possibility of a dye error.

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PMC6684588

Data are means ± SD of three separate experiments each performed in triplicate.

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PMC8973725

Five random fields were selected on each slide for scoring, and the mean score of each slide was used in the final analyses.

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PMC11467964

The primer sequences used are presented in Supporting Information S2: Table S3.

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PMC9429973

CD7-CART may result in better disease control which will translate into less disease recurrence after transplant.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CD7-CART", "may", "result", "in", "better", "disease",...

PMC9429973

The high ULBP-2/5/6 group showed a superior overall survival rate compared to the low ULBP-2/5/6 group (P < 0.01), but there was no significant difference between high and low MIC-A/B groups (P = 0.31) or between the high and low ULBP-1 groups (P = 0.52).

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PMC5916734

Unlike its orthologs in other mammals, VKORC1 from Chinese hamster carries a RRR motif flanking the first transmembrane domain and shows much lower homology with the human vkorc1 gene (Fig. 2D).

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PMC9352806

In each cycle, the most intensive 12 precursor ions with intensity above 100 were chosen for MS/MS at collision energy (CE) of 45 eV (12 MS/MS events with accumulation time of 50 msec each).

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PMC9429973

A. Dorofeeva, I. Shipounova, A. Luchkin, Z. Fidarova, E. Mikhailova National Research Center for Hematology, Moscow, Russia Background: Aplastic anemia (AA) is a heterogeneous blood system disease characterized by the bone marrow (BM) aplasia in and pancytopenia.

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PMC10335954

C Result from TRIP13 inhibition on cell clone formation ability of AGS and MGC-803 cells.

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PMC10055960

This may be due to a mechanism of action where an additive effect of the suitable physico-chemical properties of the acetate-bearing compound 8 results in enhanced activity when compared to complex 3.

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PMC5854676

The mathematical model for fluorescence (a.u) is shown in Fig. 13.

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PMC9895440

Images from immunofluorescence images were recorded on a Nikon Ti with a Yokogawa CSU-W1 spinning disk module on a Photometrics 95B (22 mm back-illuminated sCMOS) camera.

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PMC9429973

Score change from baseline across visits for all subscales of EORTC QLQ-C30 was analyzed with mixed models.

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PMC7053076

Data are expressed as mean ± SEM.

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PMC9429973

Patients had received a PI, IMiD, and anti-CD38 antibody.

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PMC9545714

The human skin is exposed to various sources of oxidative stress including ultraviolet light, ozone, and other air pollutants and metabolism of resident microorganisms. , ,

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PMC8540692

Only one freeze-thaw cycle was used regarding Aza to ensure maximal stability.

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PMC11085211

Each H NMR spectrum consisted of 256 scans (corresponding to 16 min) with a relaxation delay (RD) of 2 s, acquisition time of 0.707 s, and spectral width of 9595.8 Hz (corresponding to δ 16.0).

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PMC11754094

These results suggest that the sequence close to the prime editing site might contribute to the potential for large-deletion events.

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PMC9429973

I. Schwaner, H. Hebart, C. Losem, T. Wolff, K. Famulla, J. Huelsenbeck, B. Schmidt, T. Nösslinger, D. Rossi Onkologie Kurfürstendamm, Berlin; Kliniken Ostalb, Mutlangen; MVZ Onkologie und Hämatologie, Neuss; Onkologie Lerchenfeld, Hamburg; AbbVie Deutschland GmbH & Co KG, Wiesbaden; Hämatologisch-Onkologische Gemeinsch...

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PMC7192625

The network representation is particularly useful when using PCHi-C networks, where we can subdivide the whole network into interactions involving only promoters (PP subnetwork) or those involving a promoter and an Other-end (PO subnetwork).

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PMC9429973

A heavy comorbidity burden, namely 3 or more comorbidities (HR 2.956; 95% CI 1.403-6.227), advanced age, namely ≥70 years (HR .809; 95% CI 1.651-4.779), myelofibrosis (HR 2.501; 95% CI 1.384-4.519), and ICU admission (HR 2.669; 95% CI 1.641-4.342) independently predicted FR.

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PMC11490153

All qPCR amplifications were performed in triplicate, and primers are listed in Table 1.

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PMC11621565

At 10 µg/ml, no change appeared, while at 40 µg/ml there was a 1.77-fold increase (p = 0.007).

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PMC11496491

The results of GO enrichment analysis of DEGs were presented in terms of cell component CC, biological process BP and molecular function MF.

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PMC7723249

IFN-γ was not detected.

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PMC9318744

In conclusion, we developed a suitable human cell model for SARS-CoV-2 susceptibility.

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PMC10297204

However, the anti-tumor effects of ethanol adjuvant therapy on the STS field has not been established.

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PMC10243817

Recently, epithelial cells have been indicated as an origin of collagens in idiopathic pulmonary fibrosis (44).

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PMC9429973

Image: Summary/Conclusion: In summary, our data show that the LSCs react differently than normal HSCs to changes in AHR signalling.

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PMC9583612

Because measurements by both SeekOps and Bridger were contemporaneous, potential diurnal variations in emissions are not expected to bias this approach.

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PMC11701801

I, Representative immunohistochemical staining of cleaved PARP and cleaved caspase-3 in xenografts derived from SMARCA4/SMARCA2-deficient DMS114 cell lines and isolated from mice treated once daily for 20 days with 30 mg/kg CP-C27: Scale bar, 100 μm.

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PMC11678368

The M–Cl bonds are positioned above and below the molecular plane in trans configuration.

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PMC11638255

c Volcano plot of genes upregulated and downregulated in TEPA-treated high versus low regions of interest.

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PMC11155445

Novel acyl thiourea (149) was synthesized and subjected toward drug-likeness property and binding affinity with σ1R crystal structure 5HK1.

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PMC11585254

The next day, cells were seeded at a density of 20,000 cells per well of a white-walled clear-bottom 96-well plate and grown overnight at 37°C.

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PMC7987994

Although the choice dramatically influences the results of cytotoxicity, we have not found any papers comparing those two modes of exposition.

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PMC11695546

Many studies illustrated the possibility of using crude coconut oil as adjuvant therapy in animals infected with H. pylori and developed gastric ulcer [Selvarajah et al. 2015; Meng et al. 2019).

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PMC6267596

Quality clustering analysis performed after calculating the Z-score (Figure 3b) which found 1,234 genes were up-regulated, and 3,186 genes were down-regulated in treatments vs. controls.

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PMC11758416

Adjust the flask size based on the cell number required.

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PMC11754094

Compared with targets with a TC motif, those without a TC motif had a lower frequency of either large-deletion events or small indels due to AYBE (Fig. 4b,d).

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PMC11026382

Again dotted lines indicate multiple intermediate reactions summarized with a single line.

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PMC11612626

High-throughput screening was performed to identify compound A, a novel molecule that selectively increased immunoproteasome activity and expanded the number and diversity of MHC-I–bound peptides presented on multiple myeloma cells.

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PMC10588957

We examined whether DATS had an inhibitory effect on the growth of HepG2 cells, as well as the mechanism of DATS-induced pro-apoptotic autophagy, and clarified the potential role of the AMPK/SIRT1 signalling pathway.

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PMC9429973

AITL is an aggressive malignancy with a poor prognosis, and its clinical manifestations vary greatly among individuals.

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PMC11243198

Notably, BAS 07019774 showed significant effects on both U87MG and T98G cell viability (with IC50 values of 9.5 and 29.5 μM, respectively) (Figure 5B).

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PMC11627398

SLC31A1, also known as copper transporter 1 (CTR1), is a key copper transporter .

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PMC11310713

Scale bars, 100 μm.

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PMC11594641

Silver staining of the SDS-polyacrylamide gels was performed to visualize the protein content of the sEVs and cell lysates.

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PMC11534035

On average, the tumor sphere formation at 15 days after transfection (Figure 6A) showed an average reduction in knockdown compared to control cells; however, the difference was not statistically significant.

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PMC11539788

Next, the beads were washed with IP lysis buffer, followed by boiling in 50 µl of SDS loading buffer.

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PMC4355729

Linear correlation analysis was used to determine relationship between PIK3R1 and NCAD mRNA expression.

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PMC3995603

The HPLC chromatograms of the standard solution and water extract of A. capillaries are shown in Figure 1B and C. The contents of the six constituents ranged from 0.44–43.14 mg/g.

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PMC11574271

Images of tumors from individual mice were captured on day 32 following the injection of J82 cells.

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PMC9429973

In some patients, imaging was the only technique applied to detect residual disease.

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PMC11705630

Moreover, we found increased mRNA expressions of ISGF3 target genes in GLDC knock-downed ACHN and Caki-2 cells (Fig. 3B).

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PMC11694625

The results of docking suggested that CDK2 may be one of the targets for 3b and 3c.

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PMC9780037

Using this modification procedure, each cyt c molecule was bound to either four or eight PEG molecules.

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PMC9895440

Despite its upregulation in exhausted TILs, SNX9 is rather ubiquitously expressed in humans.

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PMC8010066

All tests were done in triplicate.

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PMC8303372

The level of significance was set at 0.05.

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PMC9587866

1,7-dihydroxy-3-methylanthracene-9.10-dione also exhibited a downregulatory effect on CTSD gene, helping EWS cells to metastasize.

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PMC5963610

Activation of EGFR results in the phosphorylation of several downstream proteins, which promote cell proliferation, invasion and metastasis .

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PMC9509578

Their findings indicated that smaller AuNPs have more efficient binding with P-gp, whereas larger-size nanoparticles avoid effective recognition by P-gp .

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PMC11095939

However, they did not observe the decreased mRNA levels of both LXR isoforms (Nr1h3 and Nr1h2) mainly because they monitored the transcriptional levels at 1 d post-PHx, which was not early enough to capture the upstream changes in transcriptional regulation.

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PMC5963610

It is important, however, to take into account the potential difference between NGcGM3 and NAcGM3 gangliosides in terms of their interaction with the EGFR and the uPAR/integrin pathways.

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PMC11583010

E, tumor volume measured using a caliper [V = (L × W × H) × π/6)].

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PMC11721587

WB analysis of Fu and Ci phosphorylation (top) and qRT-PCR of ptc mRNA (bottom) in Cl8 cells treated with increasing dose of Hh for 6 hours. (

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PMC10728200

C Western blotting was performed to assess the level of GPX4 in GIST-T1 cells transfected with GPX4 overexpression plasmids or control plasmid, and treated with IM (50 nM for T1 and 200 nM for 882) in the absence or presence of MG132 (5 μM) for 24 h. D STUB1 overexpression inhibited the stability of the GPX4 protein in...

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PMC11406030

No signs of toxicity were detected, even at a very high dose of 40 mg/kg, which will allow optimization of the dose and administration frequency depending on the stability of the peptides in the serum, which we propose to determine.

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PMC11745823

The WB was utilised to evaluate MCM7, PCNA, PI3K, phosphorylated PI3K (p‐PI3K), AKT, phosphorylated AKT (p‐AKT) and c‐Myc expression levels.

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PMC9429973

Indications for neuroimaging [(magnetic resonance imaging (MRI) or magnetic resonance angiography (MRA)] in our center include recurrent episodes of syncope, epileptic seizures, neurocognitive changes, time-averaged maximum mean velocity (TAMMV) of the middle cerebral or intracranial internal carotid arteries (ICA) mea...

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PMC9219615

was thus retested for its ability to induce cell death in other cell types.

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PMC9429973

None transformed into blastic-phase disease.

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PMC11387401

Other proteins displaying strong, abundant RNA interactions are Nucleocapsid, Tat, Integrase, Gag, and Rev. The few interactions found for GP41, Vpr, and Vif are rather weak and sparse (Fig. 2C).Figure 2Overlap and correlation between HIV-1 protein–RNA interactors identified by four nRIPseq workflows.(A) Venn diagrams ...

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PMC8735881

For example, it was found that 10E8 exhibited increased activity in neutralizing HIV-1 mutants resistant to a fusion inhibitor peptide (C34) .

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PMC11459296

Analysis of IFNγ secretion revealed significantly higher levels in all three cell types following stimulation (Figure 2E–G).

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PMC10291556

Lactate production.

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PMC11129910

Mammalian expression vectors with different oncogene inserts and control vectors were transfected into Phoenix cells cultured in DMEM media, and Lipofectamine was used as the transfection agent (Invitrogen, NY, USA) along with viral packaging vectors.

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PMC9813422

Viral gene expression is regulated by epigenetic changes in viral episomes through EMPs and associated proteins.

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PMC11502327

The mechanism is related to reducing the production of integrin α5β1 heterodimer, stimulating the proliferation of immune cells, and enhancing the activity of macrophages and T cells (62).

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PMC11476666

In the postformation culture, RSV seemed to be the more effective molecule, decreasing the CD44 expression levels in a significant manner (p < 0.05) in comparison to untreated and DMSO-treated cells.

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PMC9895440

Fig. 5Deletion of SNX9 improves CAR T cell anti-tumor efficacy.a Schematic representation of the CAR T cell transfer experiments.

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PMC9429973

Cytoreduction at registration comprised 44% of patients on hydroxycarbamide, 18% on Pegylated interferon, 16% on ruxolitinib and 8% on no therapy.

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PMC11471157

Fig. 2Morphology of various cell spheroids with or without DFP Phase contrast microscopy revealed that HaCaT cells, NIH/3T3 cells and CAF cells initiate cell spheroid formation from Day 1.

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