Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
 Community
1
PMCID
string
Sentences
string
ner
list
PMC11298021
Stem-loop based cDNA synthesis kit for miRNAs’ expression analysis was purchased from AnaCell company (Tehran, Iran) and applied as previously described.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11786767
Further investigations are needed to reveal if all these lipids or specific types of lipids are enriched around the periphery of condensed chromosomes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Further...
PMC9429973
There was no significant difference in the incidence of fever and duration of fever between two groups(P＞0.05)． Summary/Conclusion: The efficacy of PEG-rhG-CSF in promoting hematopoietic recovery after allogeneic hematopoietic stem cell transplantation is good, without severe untoward effects.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3019555
This result is consistent with the lack of 2ME2-mediated microtubule depolymerization in 1A9/2MRC cells (Fig. S1 A; Escuin et al., 2009) and further supports the notion that microtubule disruption is required for and precedes HIF-1α translation inhibition.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11607638
In this regard, high throughput screening of novel small molecules targeting the mosquito sulfakinin receptor will be helpful. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this", "regard", ...
PMC11496728
The primary antibody was recovered after 12 h, and the membrane was washed with the pre-prepared TBST three times, 10 min each time.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10198699
This includes the relevant jurisdiction’s statute law and common law, which may have its roots in centuries or millennia past.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "incl...
PMC9000591
The SI values of SE3 and SE4 were 1.92 and 1.34, respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "SI", "values", "of", "SE3", "and", "SE4", "were", "1.92", ...
PMC11085211
Additionally, UHPLC-MS was performed both in the support of NMR analysis and in an attempt to identify the molecules present at the lowest concentrations.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11737091
Similarly, the results of the KEGG enrichment analysis revealed that multiple pathways significantly enriched were related to cell division, such as the cell cycle (hsa04110) and homologous recombination (hsa03440).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Because epcoritamab and R have distinct mechanisms of action and generally non-overlapping toxicity profiles, combining these treatments may safely enhance antitumor response.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Because...
PMC8584319
Furthermore, the phosphorylation status of 4E-BP1 in AZD8055-treated HepG2 cells did not change after pre-treatment with the ERK1/2 inhibitor refametinib or the p38 inhibitor SB203580 for 1 h before AZD8055 treatment (Figure 3c,d).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8469018
Another known mechanism of action of leflunomide is the inhibition of tyrosine kinase activity associated with cytokines and growth factor receptors .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Another", "known", ...
PMC10898159
BRD4 (function as “readers”), HAND1 and BRAX1 positive regulate the core TF network.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "BRD4", "(", "function", "as", "“", ...
PMC11623887
Erythema infectiosum, arthropathies, myocarditis, transient aplastic crisis, fetal death and/or hydrops fetalis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Erythema", "infectiosum", ",", "arthropathies", ",", "...
PMC5261804
SRC was a component of 3 of the top 20 PPIs, and the top two PPIs across all cell lines were CTNNB1-SRC and SRC-AKT1, suggesting that the SRC-AKT1-CTNNB1 pathway is of potentially general interest for targeting PPIs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11502066
Mutated GPCR genes have been indeed identified in more than a fifth of studied malignancies, with the highest mutation rate in gastrointestinal adenocarcinomas .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11297139
ARID1A has been shown to be frequently mutated in cancers, and recurrent mutations in ARID1A have been identified in a wide variety of cancers, including ovarian, breast, and pancreatic cancers.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11787651
Dynamic collision energy was enabled and ranged from 14 to 46 V. The LC gradient and SWATH isolation scheme were optimized for either a 10-min linear gradient from 5 to 32% solvent B or a 5-min linear gradient from 5 to 30% solvent B. TOF MS accumulation time was 100 ms, and MS2 accumulation time was 10 ms.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11703896
Specifically, this study seeks to explore whether rapamycin can exhibit binding affinity to key cancer-related receptors, including EGFR, MET, FGFR, ROS1, and ALK, and to characterize the molecular interactions underlying these potential bindings.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10812665
Strictly speaking, these findings refer to the 24 h time point.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Strictly", "speaking", ",", "these", "findings", "refer", "to", "the", "24", ...
PMC5311252
CDKN1A (p21) is a cyclin-dependent kinase (CDK) inhibitor that binds to and inhibits the activity of cyclin/CDK complexes resulting in RB1-dependent inhibition of activating E2F transcription factors.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
A total of 355 patients (5.7%) developed 376 SPMs, of which 56% were solid organ malignancies, and 44% were hematologic neoplasms.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11244823
However, only two of the 14 “true positive” sera reacting with gD1_83 antigen came from unvaccinated horses, whereas 11 came from horses with documented history of repeated vaccination against EHV-1 and one serum came from a horse with unknown vaccination status.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11628904
C. albicans colonisation of control and isotonic medium treated tissue 1 hpb. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "C.", "albicans", "colonisation", "of", "control", "and", "isotonic", "mediu...
PMC10093184
Our analysis only revealed a correlation between CD270 and CD274 expression (high expression in COS3600 and COS4074) but not with CD276, despite the strong correlation between all three markers observed by Cascio .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "...
PMC11521786
To detect the presence of the enzyme caspase 3 (in its active form) in the treated cells, a MAb specific for a fragment resulting from the proteolytic activation of this enzyme, conjugated with the Alexa-Fluor488 fluorophore, was used.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11502962
Cell clusters were visualized by uniform manifold approximation and projection (UMAP) in these two tumors.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "clusters", "were", "visualized", "by", ...
PMC11637276
Scale bar, 20 μm. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ",", "20", "μm", ".", "(" ] } ]
PMC9429973
Alterations in mitochondrial activity and metabolic profile, in response to IO, are expected to negatively impact HSC function.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Alterations", "in", "mitocho...
PMC10589262
To detect the cellular localization of MT-KIT (GIST cells: GIST430 and GIST882) and wild-type KIT (colon cancer cells: DLD-1 and Colo320DM), immunocytochemistry (ICC) analysis was performed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O"...
PMC11049294
Furthermore, no difference in fluorescence intensity could be detected upon DGJ addition of Fl-Gb3-treated Jurkat GLA KO cells (Figure 3E).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9681981
The sedimented bacteria were washed using 1 ml of PBS, containing 0.1% cysteine, and stored at -70°C until the time of real-time polymerase chain reaction (RT-qPCR) assay.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11422497
circ_SMA4 Promotes GISTs cell Invasion and Migration In Vitro. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "circ_SMA4", "Promotes", "GISTs", "cell", "Invasion", "and", "Migration", "In", "Vitro", ".", ...
PMC11597291
Then, the cells were treated with PCT and nCGO-PEG/PCT particles at indicated concentrations (0, 1, 5, 10, 17, 25 μg/mL of drug) for varied time periods of 5, 24, and 48 h. The blank nCGO-PEG (no drug) and nCGO (no PEG, no drug) particles were also evaluated as controls at similar concentrations to the drug-loaded ones...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11277157
JNK phosphorylation and Bcl2 dissociation are affected by DJ-1 levels.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "JNK", "phosphorylation", "and", "Bcl2", "dissociation", "are", "affected", "by", "DJ-1", "levels...
PMC9509578
Their results indicated that increased drug release is dependent on the redox environment in MCF-7/ADR drug-resistant cells, ultimately resulting in downregulation of P-gp expression.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC3019555
Together, these results indicate that, in concert with the microtubule cytoskeleton, P-bodies regulate HIF-1α translation and that HIF-1α mRNA can return to a translationally active state once the cellular stress of microtubule disruption is relieved.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Interestingly, these sites were predominantly associated with enhancers of genes expressed in mature myeloid cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interestingly", ",", "these", "sites", "were", "predom...
PMC9046263
As these cell lines genomes fundamentally differ from the standard human genome, this may have similarly affected our analysis of HERVs in our cell lines of interest.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
They correlated with EORTC QLQ-AA/PNH PF (R=0.499, P=0.006), ST (R=0.395, P=0.034) and FA (r=-0.517, p=0.004).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11307990
Statistical analysis was conducted using GraphPad Prism software.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "analysis", "was", "conducted", "using", "GraphPad", "Prism", "software", "." ] } ]
PMC11767793
An analysis of assay variability factors have determined that the lack of standardization here is a major issue.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", "analysis", "of", "assay", "varia...
PMC9429973
The patient specific pO2 at which sickling starts (PoS) along with RBC deformability at normoxia (EImax) and upon deoxygenation (EImin) can be measured by oxygen gradient ektacytometry (Laser Optical Rotational Red Cell Analyzer (LoRRca)).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8469018
Stock solution of teriflunomide (A771726) was prepared in DMSO, and then serially diluted with methanol to solutions of 0.25, 0.5, 1, 2.5, 5, 10, 25, 50, and 100 µg/mL. A working internal standard solution of warfarin (100 µg/mL) was prepared in methanol.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Donor lymphocyte infusion (DLI) is an immunotherapy that can be used after alloHSCT in patients with high-risk disease (prophylaxis), mixed donor chimerism or minimal residual disease (preemptive) and relapse (therapeutic).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
In patients with lymphoma, humoral response is weaker and almost universally abrogated in patients who received anti-CD20 monoclonal antibodies.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "patients", "with", ...
PMC11087055
The expression of Brachyury indicated that ΔDEP-GFP-PS cells maintained their identity (Figure 1E) but displayed a shorter and wider morphogenesis than the control PS (Figure 1C–E, n≥4 for each).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11746942
Notably, CYM alone did not activate STAT3 (Fig. S3E), indicating that S1PR3 acts as an amplifier of IL-6-mediated STAT3 activation rather than an independent activator.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10887351
Cero et al. described the importance of β3-ARs in human brown/beige adipocytes to maintain the multiple components of the lipolytic and thermogenic cellular machinery , since the β3-AR silencing compromised the genes essential for FFA metabolism mitochondrial mass and thermogenesis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Seven patients (7.1%) had a severe infection (meningitis, sepsis, osteomyelitis) caused by Streptococcus Pneumoniae in 3/7 cases.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11537649
The deeper regulatory mechanism will be explored to promote clinical translation and application.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "deeper", "regulatory", "mechanism", "will", "be", "explored", "to", ...
PMC11534377
For example, studies have shown that 5-Aza enhances the efficacy of radiotherapy in head and neck squamous cell carcinoma (HNSCC) and pancreatic cancer by modulating the tumor microenvironment and enhancing the immune response .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11593713
Human adenovirus 5 (Adenoviridae, DNA virus) is one of the adenovirus serotypes that can infect humans.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Human", "adenovirus", "5", "(", ...
PMC11206251
In addition, the effect of PEIM on the levels of inflammatory factors (TNF-α, IL-1β, and IL-6) was determined using the ELISA kit.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11496728
Cell pools were expanded, and monoclonal cells were screened using limiting dilution.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "pools", "were", "expanded", ",", "and", "monoclonal", "cells", ...
PMC10976516
Another important aspect of combinational ICI with chemotherapy or OV therapies in clinical trials so far is the occurrence of patients undergoing complete tumor regression (so-called "elite responders").
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11467964
Despite these strong findings, limitations still exist.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Despite", "these", "strong", "findings", ",", "limitations", "still", "exist", "." ] } ]
PMC11680562
As a result, the drug release rate decreases over time because the available surface area for release decrease.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "a", "result", ",", "t...
PMC9429973
MFI and HbA output were positively correlated, and the top DNA donors resulted in HbA expression on par with physiologic levels.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MFI", "and",...
PMC10914904
vtRNAs may remain unprocessed and protected from methylation by the SRSF2 protein.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "vtRNAs", "may", "remain", "unprocessed", "and", "protected", "from", "methylation", ...
PMC7759933
Each of these techniques offers various advantages; however, many are technically challenging, expensive, and need appropriate facilities .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "of", "the...
PMC11319300
Data is visualised using the WashU Epigenome Browser.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "is", "visualised", "using", "the", "WashU", "Epigenome", "Browser", "." ] } ]
PMC9985266
The beads were washed with NETN buffer three times to remove nonspecific binding.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "beads", "were", "washed", "with", "NETN", "buffer", "three", "...
PMC4485786
Influence of FcIL-7, NHS-IL12/FcIL-7, and NHS-IL12/IL-2MAB602 on innate immunity. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Influence", "of", "FcIL-7", ",", "NHS-IL12/FcIL-7", ",", "and", "NHS-IL12/IL-2MAB602",...
PMC8735881
Fourth, GPI-10E8 and its bifunctional derivatives (CMI02 and CMI06) were highly effective in transduced human CEMss-CCR5 cells to inhibit both CCR5- and CXCR4-tropic HIV-1 isolates and the modified cells experienced a robust survival selection under HIV-1 infection.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", ...
PMC11706776
Overall, these results indicate that KCNN1 expression and SK1 activity are involved in the control of membrane potential and calcium influx in ES cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11708541
Govindappa et al., discussed strategies to improve the possible therapeutic outcome of 4-AP in PNI-induced bone loss and muscle repair.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Govindappa", "et", ...
PMC11478724
The results indicated that both drugs when used alone and in combination, increased the amount of ROS production.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", "indicated", "th...
PMC9479186
According to the detection of complex1 activity, we found that the activity of NDUFC1 silenced group decreased, whereas the content of ROS increased.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11583010
Measurements were performed in a CLARIOstar 96-well plate spectrophotometer (BMG Labtech).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Measurements", "were", "performed", "in", "a", "CLARIOstar", "96-well", "pl...
PMC11283030
Quantitative PCR was carried out with SYBR Green qPCR Mix (Beyotime, China) on StepOne Plus Real-Time PCR amplifier (ABI, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9268183
Altogether, these results show the importance of plants (both cultivated and their wild crop relatives), whose regular intake in diets can be beneficial and cancer preventive.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10196713
Among these three candidate genes, expression of Fdx1 in both A2780cis and OVK18cis cells was significantly higher than that in their parental cells, as assessed by RT-qPCR analysis; while the expression of Timp1 in both A2780cis and OVK18cis cells was not significantly higher than that in their parental cells and the ...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9684669
Direct inhibition of CAMKII or CREB1 had the same phenotypic effects as terfenadine in the combined treatment, including lower expression of ABCB1 and baculoviral IAP repeat-containing 5 (BIRC5, also known as survivin) and increased doxorubicin-induced apoptosis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8382973
As a consequence, the antiviral property of PrEP is abrogated (15–22).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "a", "consequence", ",", "the", "antiviral", "property", "o...
PMC11653533
Kaempferol and naringenin are common flavonoids known for a variety of bioactivities, particularly antioxidant, anticarcinogenic, anti-inflammatory, antidiabetic antimicrobial and lipid-lowering activities (Hasnat et al., 2024).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10728200
To quantitatively analyze colocalization, ImageJ software (Version 1.53, National Institutes of Health, Bethesda, MD) was utilized in conjunction with the Colocalization Finder plugin for calculating Pearson’s correlation coefficients .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11320834
The liposomal formulation of topotecan revealed the highest increase in antitumor activity in Ascites, and the studied drug combinations showed the highest dose-reduction index for OLL.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11502962
THP-1 monocytes were grown in RPMI 1640 (HyClone) supplemented with 10% FBS and 1% penicillin/streptomycin.
[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "THP-1", "monocytes", "were", ...
PMC9878278
Further, ZIKV did not induce a robust inflammatory response (Strange et al., 2018a), which may be one of the reasons why infection is not associated with severe cell death of SC unlike other susceptible cells like human neuronal progenitor cells (Ferraris et al., 2019) and retinal epithelial and endothelial cells (Sing...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11706776
After siRNA transfection, viability assays were performed on re-seeded cells, using an Omni device from CytoSMART (Axion Biosystems, Atlanta, GA, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11684821
When transduced with the MC.7.G5 TCR, CD8 T cells from patients with melanoma referred to as MM909.11 and MM909.24 were able to respond to the patient-autologous melanoma lines (18).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11377827
Schematic model of the role of USP43 in the HIF response.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Schematic", "model", "of", "the", "role", "of", "USP43", "in", "the", "HIF", "r...
PMC10123657
This result suggested that the mild mechanical dissociation of leukemic cells from the 3D co-culture did not cause significant cell membrane damage and protein leakage from the adherent OP9 cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11438317
3Identification of the Tyr targeted by LYP in several potential substrates.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "3Identification", "of", "the", "Tyr", "targeted", "by", "LYP", "in", "several", "pote...
PMC11429241
The morphology of the 3D-printed scaffolds was characterized using a scanning electron microscope (TM-3000, Hitachi, Chiyoda, Tokyo) The samples were not additionally prepared for SEM.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10840195
Cells were washed with PBS 3 times, the scratched cells were removed, serum-free medium with mitomycin C (10 µg/mL, Sigma‒Aldrich) was added, and cells were replaced into a 37 °C 5% CO2 incubator.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11200978
Analysis of Caspase 3 revealed the presence of minimal cleavage products, suggesting lesser apoptotic involvement at 6 h post freeze (Figure 7).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973
F. Huisman, D. Al-sarayfi, M. Bellido, R. Mous, J. S. Vermaat, A. P. Kater, M. Nijland, M. Brink Department of Hematology, University Medical Center Groningen, University of Groningen, Groningen; Department of Hematology, UMC Utrecht Cancer Center, Utrecht; Department of Hematology, Leiden University Medical Center, Le...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
In addition to diagnostics, the bone marrow biopsy also aids staging, management and monitoring.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", "to", "diagnostics", ",", "the", ...
PMC10588957
Reportedly, allicin induces p53-mediated autophagic cell death in liver cancer cells by activating the p-AMPK and TSC2 signalling pathways and inhibiting the mTOR and cytoplasmic p53 signalling pathways (7).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11285179
Antibody stripping and antigen retrieval were performed after each round of TSA.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Antibody", "stripping", "and", "antigen", "retrieval", "were", "performed", "after", ...
PMC11766332
miRNA epigenetic regulation in ASD has been extensively studied for both diagnostic purposes and understanding patho-mechanisms .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "miRNA", "epigenetic", "regulation", "in", "ASD", "has"...
PMC9429973
No patients had VTE recurrence or bleeding complications at the time of follow up.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "patients", "had", "VTE", "recurrence", "or", "bleeding", "...
PMC9429973
Then patients with ICUS were followed up.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", "patients", "with", "ICUS", "were", "followed", "up", "." ] } ]
PMC11638764
One key protein, origin recognition complex subunit 6 (ORC6), which is critical for cell replication and has been implicated in various cancers (Prasanth et al., 2002; Lin et al., 2003) , showed a substantial reduction in the CER and NER compartments ( Fig. 1G ).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11470999
His pull‐down assays revealed that CIP2A interacts with His‐VHL, and this interaction is enhanced with increasing PF concentrations (Figure 6H).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "His", ...
PMC6379402
The analysis of lung cancer is based on 483 cancer and 59 paired control tissue expression data from TCGA project LUAD.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "analysis", ...
PMC10547921
When excessive hydrophobic payloads conjugate to an antibody, the resulting ADC tends to aggregate and becomes unstable.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "When", "excessive", "hydrophobic", "payloads...