Datasets:
OTAR3088
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BioData-CellLine_annotated

Dataset card Data Studio Files
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PMC11194678
Scale bar: 3 μm.
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PMC9250505
Xenograft studies were performed according to the Animal Research: Reporting In Vivo Experiments (ARRIVE) 2.0 guidelines.
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PMC11228511
Scale bar, 2 µm.)
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PMC11640247
ns, not significant.
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PMC11655498
EBV-encoded nuclear protein SM is essential for lytic gene expression.
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PMC9429973
The pt treated in DL 1 did not show adequate GC502 cellular expansion.
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PMC10196713
As expected, Fdx1 depletion in OVK18cis cells resulted in a significant increase in mitochondrial membrane potential after treatment with cisplatin (Fig. 4F).
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PMC9429973
Transfused Hbb mice were treated with 120 mg/kg vamifeport once daily for 4 weeks.
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PMC10778532
Finally, western blot analysis was in favor of a more mesenchymal profile (Figure 4F and Figures S7–S9) as illustrating a downregulation of E cadherin in treated VHL-C162F cells associated with upregulation of N-cadherin, Slug and AXL (Figure 4F, Figures S3, S7 and S8).
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PMC9429973
Results: The final list consisted of 84 papers (case reports/series, abstracts, short communications).
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PMC11473843
Heatmaps in (C, E) display a relative color scheme across samples that uses the minimum and maximum values in each row to convert the values into a scale ranging from 0 to 1.
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PMC11740207
In AD, one SC divides into another SC and a PSC that will differentiate into a specific cell type.
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PMC8916024
In this way, it can guide the production of the snail industry more scientifically and effectively, and provide scientific materials for promoting the development of snail commercial feed.
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PMC11257203
Then after, the samples were treated with hypotonic KCL (0.075 M) to lyse red blood cells.
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PMC7504302
Following a manual curation, we found that among the genes with significant depletion scores DDB1, EEF2, EIF3A, HSPE1, RAN, RPS15A, RUVBL1, SNRPD1, UBA1, and VCP genes were common in both datasets and all five cell lines.
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PMC11725127
The eluted protein was then purified, concentrated, aliquoted, and snap-frozen using the same conditions as for USP2.
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PMC11777207
Error bars indicate SEM.
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PMC9429973
Image: Summary/Conclusion: Age is not a risk factor for the development of complications, given that an incidence similar to that reported in younger patients and related to known risk factors is observed.
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PMC9429973
IMC was performed to analyze the spatial position relationship and protein expression characteristics of different subgroups in the tumor microenvironment of AITL.
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PMC11591052
Furthermore, 20E displays adjuvant antineoplastic manifestation in transformed cells .
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PMC9119314
The indoloquinoline alkaloid cryptolepine (1) is the major alkaloid present in the roots of this species and is of interest as a lead to new antimalarial drugs.
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PMC9681981
The effect of exposure to Caco-2 cells on the etx gene expression was statistically significant (P<0.01).
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PMC11267830
To generate stable DCAF15-knockout cell lines using the Cas9/CRISPR system, the Cas9 gene was initially delivered into T-ALL cells through lentivirus transduction, followed by puromycin selection.
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PMC6160470
This suggests that the crown ether interaction site with P-gp either overlaps with the substrate and/or ATPase binding site, or it is linked to it in a negative allosteric fashion.
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PMC11290772
Through successful development and characterization, we have demonstrated the efficacy of ROBO1-NK cells derived from patients' own PBMCs in effectively lysing ovarian cancer cell lines, primary ovarian cancer cells, and tumor organoids.
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PMC11532793
Using the edgeR-v4 QL pipeline and Salmon’s Gibbs sampling algorithm, we performed a DTE analysis of the Illumina short paired-end read RNA-seq experiment from the human adenocarcinoma cell lines data.
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PMC11200978
Given that pyroptosis is primarily involved in inflammatory reactions and pathogen defense , we hypothesized that pyroptosis was not involved and, as such, cleaved (activated) Gasdermin D would not be detected.
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PMC10040136
The cells were identified using MSC-related markers, they expressed CD73, CD90, CD105, and CD166 but not CD34, CD45, or HLA-DR (C).
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PMC11541409
Updates in Surgery, 2023.
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PMC9429973
The median follow up was 12.5 months.
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PMC11413393
Guide RNA sequences targeting PRMT1, PRMT3, PRMT4/CARM1, PRMT6, RPA3 and the human ROSA26 locus were selected from the Broad Insitutute’s ‘Brunello Library’ (https://portals.broadinstitute.org/gppx/crispick/public, Supplementary Table 2).
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PMC11437637
Cap the tube cap, and vortex gently to mix for about 15 seconds.
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PMC7039683
For comparison, we also carried out ATAC-seq on the human embryonic palate mesenchyme (HEPM) cell line .
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PMC9318744
As shown in Figure 2B, viral nucleocapsid protein (NP) was detected in most ACE2plusC3 cells 48 h post-infection.
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PMC11768281
In particular, CD4+ and CD8+ T cells are the most frequently studied for their roles in both cellular and humoral immunity.
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PMC11583010
Cells or cell lines (10,000–50,000) expressing nectin-4 (naturally or transfected) were incubated with dose range (5 ng/mL–5 μg/mL) of the indicated antibodies.
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PMC11377827
The cells were washed five times in 1x DPBS and mounted in glycerol-based mountant with DAPI.
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PMC11521786
Although active immunotherapy constitutes an alternative for the treatment of cancer, it presents the additional challenge of activating the immune system of cancer patients suppressed by the tumor itself (37).
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PMC9429973
F. Ravandi-Kashani, A. Kishtagari, H. Carraway, G. Schiller, E. Curran, B. Yadav, A. Cacovean, S. Morris, T. Butler, J. Lancet Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston; Vanderbilt-Ingram Cancer Center, Nashville; Cleveland Clinic Foundation, Clevela...
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PMC9429973
Similarly, its Ref-1 function, which reduces oxidized transcription factors and thereby regulates transcriptional networks, has not been studied in primary adult hematopoietic cells.
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PMC5415764
Our data provided more support for the potent proapoptotic effects of P+T/iRGD LPNs.
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PMC8701144
The SwissProt database was used for the database searches.
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PMC11441402
The automated cell imaging system reliably measured viable numbers of cells, regardless of whether the cell line was adherent or suspension, as demonstrated by the number of cells counted being consistent across all three cell lines.
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PMC11457557
Growth factor receptor bound protein 2 (GRB2) is involved in VEGF signaling and DR is associated with a genetic mutation near GRB2 on chromosome 17q25.1.
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PMC9812014
The inhibitory concentrations for these alkaloids against HBV were 0.2 or 0.4 mM. These results suggest that these alkaloids are more potent than the Lamivudine drug .
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PMC11806182
B miRNA-gene interaction network for up-regulated miRNAs.
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PMC11694625
Deviations within the CDK pathway have been observed in various types of cancer.
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PMC10523483
Overexpression of H1.2 in A549 cells. (
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PMC11637284
Right, combined violin and sina diagrams of DAPI-stained kDNA area measurements, indicated as arbitrary units (a. u.), in the uninduced and induced TAC60 RNAi-cell line.
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PMC11759543
The combination of drugs, but not a single drug, induces a significant apoptosis effect, including the cleavage of PARP, caspase 8, caspase 9, and caspase 3.
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PMC11785489
Because the number of amino acids in a TCR sequence varies from cell to cell, shorter TCR sequences contain gaps at some IMGT positions.
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PMC11753435
We begin with an ensemble of bona fide, interacting peptides, which appear in cocrystals in the RCSB PDB (these peptides are taken from our training set).
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PMC6450504
After extrusion, liposomes were added to bPEI-PE films at the mol ratios of 0.1% and 0.5% (mol% of bPEI-PE:liposomal lipids).
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PMC11347429
Based on the MDS components in Figure 6A , we assigned ethnicity to almost all participants from our cohort to four ancestral groups ( Figure 6B ): African-American (AfAm, n = 46), Asian (n = 2), Caucasian (Caucs, n = 169), Mexican American Indians (Mex_AmInd, n = 4).
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PMC9429973
Overall incidence of PN was comparable between treatment arms (Pola-R-CHP: 52.9%; R-CHOP: 53.9%); most events were grade 1, and incidence of grade 2 (Pola-R-CHP: 12.2%; R-CHOP: 15.5%) and grade 3 (Pola-R-CHP: 1.6%; R-CHOP: 1.1%) events were comparable between treatment arms.
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PMC11755519
It was also discovered that the level of ErbB2 protein contained in invasive exosomes derived from bladder cancer cells is CRK dependent.
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PMC9454852
An alteration of the ER homeostasis, as with a shift in the redox state, could lead to an ER stress condition .
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PMC5173112
Western blotting was used to detect the protein expression of IL-8 in ALDH and ALDH 786-O and A-704 cells. (
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PMC11723947
In average, mean (SD) x10 cells were recovered per cryovial with a mean cell viability of mean (SD) % after the exclusion of N subject PBMC that did not meet a 20 ± 4 h post-thaw viability criteria of ≥ 80%.
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PMC11738017
MM cells were cultured alone for the first 48 hours to allow the accumulation of sBCMA in the culture media, thereby mimicking in vivo conditions.
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PMC11591030
Moreover, AOP at concentrations ranging from 50 to 250 μg/mL effectively reduced the increase in the 8-OHdG and ROS content, with no significant difference observed between the AOP and VA treatment groups (p < 0.05).
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PMC7081114
As shown in Figure 4, the shKIF21B group had lower cell viability compared to the shCtrl group with the difference being statistically significant at 4 d and 5 d post-transfection.
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PMC11507371
Following 10 min incubation at 37 °C, 500 μL pre-warmed serum was added.
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PMC11397654
It is worth noting that the N-methyl-D-glucamine itself did not show any cytotoxicity against both cell lines.
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PMC9454852
We previously observed in REN cells the presence of csGRP78 and also the secreted form in the conditioned medium .
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PMC11730000
The reported anticancer activity of EGCG, including its ability to induce apoptosis in cancer cells, is attributed to these prooxidant characteristics.
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PMC5363531
mD→PEM was the most valuable treatment in impairing TS transcriptional activity.
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PMC9429973
We calculated an EASIX score for all patients and an ‘EASIX-F’ score based on the values provided by Greenbaum et al (EASIX-F1) and our own interquartile values (EASIX-F2).
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PMC11727638
The sections were stained with hematoxylin and eosin and observed using a fluorescence microscope.
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PMC11791203
AO, which stains both live and dead cells, emits green fluorescence, while EB intercalates with DNA and fluoresces red in cells with disrupted membrane integrity.
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PMC9429973
Health-related data were collected at the first consultation (baseline) and during follow-up visits.
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PMC11750712
CAR T detection in lymph nodes by PCR and IF PTCL is an area of unmet clinical need.
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PMC6442998
Total RNA was extracted using RNeasy MiniKit (Qiagen, Valencia, CA, USA) according to the manufacturer’s instructions.
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PMC11519583
The representative data from one of two independent experiments are shown.
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PMC11306331
For all microscopy experiments, optogenetic stimulation was carried out using a 450 nm LED light source (X-Cite XLED) was applied with an LED and delivered to the region being imaged through a digital micromirror device (DMD; Mightex Polygon 400) for 1 sec per acquisition cycle (with 10 sec between acquisitions).
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PMC8481254
To date, the roles of CA in diabetes-associated liver cancer have not yet been determined.
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PMC8873393
Uncovering how dramatic changes to the transcriptional program contribute to TC-NER (transcription-coupled nucleotide excision repair) is important in DNA repair research.
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PMC11252553
mL-1)+62.5(R2=0.9943) Eq(2) The scavenging effect of different concentrations of Taurine (...) & cysteine (---) on DPPH radical at 517 nm.
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PMC10932641
NC, negative control; lncRNA, long noncoding RNA; SI, silent; OE, overexpressive.
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PMC10818062
At the PM, PI4P, synthesized from PI by PI4KIIIα, is further phosphorylated to PI(4,5)P2, which is hydrolyzed upon BCR activation by PLC into IP3 and DAG.
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PMC3915447
FA (10, 30, 50, 70, 100, 150 and 200 µM) was added to the culture medium containing CCRF CEM cells and incubation was done for 72 hours at 37 C Effect of SPIO-FA on the apoptosis of CCRF CEM cells for 72 hours.
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PMC10734950
Thus, F8 was able to depolarize the mitochondria in CCRF-CEM cells.
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PMC9429973
Moreover, CD44 presented in acceptor cells is involved in the development of drug resistance in leukemic cells, by promoting activity of efflux transporters.
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PMC8389560
ImageJ, Origin 2016 (OriginLab, Northampton, MA, USA), and Prism GraphPad 7 (GraphPad Software, RRID: SCR_002798) software was used for data and statistical analysis.
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PMC11577421
In contrast, NP_BSA– experienced a barrier effect from the glycocalyx, attributable to the absence of attractive BSA-GAG interactions in this case.
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PMC10329237
All data represent the mean ± SD from triplicate samples for each treatment. **
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PMC11218145
Representative traces of Ca dynamics are shown on the left TB affects the Ca transmission from ER to mitochondria.
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PMC11754094
Using the Repair-seq dataset and genes associated with DNA repair in the Human Protein Atlas website, we selected 794 genes associated with DNA repair and categorized them into specific repair processes or pathways.
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PMC11655536
Human bone marrow (BM) samples from MM patients were collected according to a protocol approved by the Institutional Review Board of The First Affiliated Hospital of Jinan University, with patients informed consent acquired in accordance with the Declaration of Helsinki.
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PMC11703992
The trajectory predicted in GCA and old samples both indicated that CD4+ Memory T cells were in the later-middle stage of differentiation, while CD4+ Memory T cells in GCA showed an individual terminal stage in differentiation trajectory.
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PMC8973085
After observing a yellow precipitate, the mixture was allowed to cool.
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PMC9503685
GraphPad Prism program was used to statistically evaluate the results.
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PMC3730428
SAHA was obtained from Selleck Chemicals (Houston, TX, USA).
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PMC11321678
We then compared the gene score (a proxy for gene expression) and motif deviation score (a proxy for TF binding activity) for each TF across all single cells.
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PMC11711066
Astragaloside IV (As‐IV), a key component of traditional Japanese Hozai tonics, has a steroid skeleton like estrogen.
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PMC11502327
In alkaloids, the position of benzoyl, benzyl, and alkyl is related to their anti-tumor effect, and the structure that plays a key role or irreplaceable role in the compound is often called a “privileged scaffold”.
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PMC9587298
The ESI-MS and MS/MS fragmentation were identical to the fragmentation when using isolated standards (Fig. 2, Fig. 3, Fig. 4).
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PMC11424574
Importantly, there was no noticeable difference in body weight between the shLuc and shMTA2 mice (Figure 6C).
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PMC10654497
We cultured Beas-2B, A549, and H1299 cell lines in high glucose DMEM medium containing 10% fetal bovine serum (FBS).
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PMC10243817
The overlapping mRNAs in RNA-Seq and iRIP-Seq experiments are considered as those bound and regulated by MEX3B in BEAS-2B cells, and we identified 7 overlapping genes (Figure 2D).
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